Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_024937353.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_015596535.1 1 Reactome: R-HSA-156581 "Methylation" XP_024941858.1 10 KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23 "Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Galactose metabolism";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_015609275.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015596957.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_015585954.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015587361.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_024937672.1 3 Reactome: R-HSA-70350;Reactome: R-HSA-9639288;Reactome: R-HSA-168928 "Fructose catabolism";"Amino acids regulate mTORC1";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_015607497.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015604731.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592 "Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1" XP_024935744.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_024940094.1 18 Reactome: R-HSA-5689901;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;MetaCyc: PWY-7511;Reactome: R-HSA-6796648;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Metalloprotease DUBs";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Protein ubiquitination";"TP53 Regulates Transcription of DNA Repair Genes";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_015593163.1 12 MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)" XP_015605880.1 26 Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-69205;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-8866654;Reactome: R-HSA-6804114;Reactome: R-HSA-5656169;Reactome: R-HSA-4615885;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-1362277;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-6782135 "Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G1/S-Specific Transcription";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Polymerase switching";"Removal of the Flap Intermediate";"E3 ubiquitin ligases ubiquitinate target proteins";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Termination of translesion DNA synthesis";"SUMOylation of DNA replication proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Transcription of E2F targets under negative control by DREAM complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER" XP_015588634.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" XP_015584727.1 14 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5656121 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Polymerase switching";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI" XP_015603042.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024941196.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_024945497.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_024944109.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_015604954.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_015600565.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024943421.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_015592193.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015609474.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015609793.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015607475.1 10 MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158 "1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism" XP_024936158.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015594086.1 27 Reactome: R-HSA-5358751;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5250924;Reactome: R-HSA-5358752;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-399956;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-5467337;Reactome: R-HSA-5610783;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;KEGG: 04714+2.7.11.1;Reactome: R-HSA-196299 "S45 mutants of beta-catenin aren't phosphorylated";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"B-WICH complex positively regulates rRNA expression";"T41 mutants of beta-catenin aren't phosphorylated";"Human cytomegalovirus infection";"Misspliced GSK3beta mutants stabilize beta-catenin";"CRMPs in Sema3A signaling";"mTOR signaling pathway";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of RUNX2 expression and activity";"APC truncation mutants have impaired AXIN binding";"Degradation of GLI2 by the proteasome";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Thermogenesis";"Beta-catenin phosphorylation cascade" XP_015592431.1 5 Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756;Reactome: R-HSA-936440 "ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling" XP_015595689.1 4 KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931 "Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_015606041.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024939051.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015598943.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_024943353.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_015609881.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015589469.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation" XP_015609508.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015586022.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015593176.1 26 Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862 "PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"Circadian Clock";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_024935879.1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142 "Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_024941640.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_015606136.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_015603036.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015599024.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015590424.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_024942744.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015601774.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015605357.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607623.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015589790.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015597223.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024936501.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015600273.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962 "Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex" XP_015585802.1 12 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection" XP_015593803.1 17 Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5358565 "Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Polymerase switching";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_015605194.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015596442.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_015609271.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_015584759.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015603681.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024942771.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024947530.1 5 KEGG: 00240+2.4.2.4;MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.4;Reactome: R-HSA-73621 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism" XP_024938893.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_015606217.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015610331.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015599639.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015598376.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015593144.1 18 KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409 "Ether lipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_015595372.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015597670.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_015600190.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024945203.1 9 Reactome: R-HSA-69202;Reactome: R-HSA-6804114;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-69231;Reactome: R-HSA-69205 "Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin D associated events in G1";"G1/S-Specific Transcription" XP_024938208.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion homeostasis";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade" XP_024937954.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015589078.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_015585499.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015588588.1 7 KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205 "Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose" XP_024942631.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015589614.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015609332.1 42 Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-606279;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-110328;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-977225 "RMTs methylate histone arginines";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Meiotic synapsis";"HDACs deacetylate histones";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Deposition of new CENPA-containing nucleosomes at the centromere";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Amyloid fiber formation" XP_015606279.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_015608860.1 4 Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I" XP_024936159.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015610588.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015600587.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015598486.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015603192.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription" XP_015602701.1 40 Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-168325;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-6782210 "PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Viral Messenger RNA Synthesis";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_015587428.1 33 Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-180910 "Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs" XP_024945160.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_015592365.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024943740.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015589900.1 2 MetaCyc: PWY-5629;KEGG: 00311+1.21.3.1 "Isopenicillin N biosynthesis";"Penicillin and cephalosporin biosynthesis" XP_015605150.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024945168.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_024937469.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_015588784.1 12 Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2122948 "Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_024945246.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_015600699.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis" XP_024942942.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015590323.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024936040.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015590284.1 7 Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015592645.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_015595339.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015592155.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_024937915.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015610143.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_015594352.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015600415.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_015590326.1 4 KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270;MetaCyc: PWY-4261 "Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate";"Glycerol degradation I" XP_015605007.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015607430.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083 "ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions" XP_015584696.1 9 KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III" XP_024936111.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015607202.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_024940847.1 18 MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4 "Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism" XP_015595402.1 20 Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121 "HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI" XP_015600433.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015600998.1 2 Reactome: R-HSA-804914;Reactome: R-HSA-9029569 "Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_015593472.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024944367.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015600660.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015606819.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015599193.1 9 Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-5674135;Reactome: R-HSA-9639288 "Macroautophagy";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"MAP2K and MAPK activation";"Amino acids regulate mTORC1" XP_015599467.1 14 MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8055 "Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis" XP_015586547.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015585717.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015601384.1 11 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015606109.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_024943104.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015598006.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_015584995.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_024936556.1 12 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection" XP_015593361.1 9 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_015598273.2 9 MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18 "Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Glutathione metabolism" XP_024944452.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_015603080.1 6 MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433 "Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation" XP_024939252.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015594264.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024936014.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_015609015.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015601451.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_024945811.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015587616.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_024939713.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015598681.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015587514.1 11 Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"HS-GAG biosynthesis" XP_015590256.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024945498.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024947249.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015595013.2 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015597032.1 5 Reactome: R-HSA-171007;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-168638 "p38MAPK events";"DSCAM interactions";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway" XP_015591560.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015602310.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015597895.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_024937127.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-70263 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"Biotin transport and metabolism";"Gluconeogenesis" XP_015587433.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015596919.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_015597341.1 11 Reactome: R-HSA-4043916;MetaCyc: PWY-3861;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-6992;MetaCyc: PWY-7456;MetaCyc: PWY-7586 "Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_015586479.1 24 Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-4086398;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-456926 "Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (s) signalling events";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Ca2+ pathway";"Glucagon-type ligand receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)" XP_024945341.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938 "Dual incision in TC-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)" XP_024945252.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024946454.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161 "RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation" XP_024940443.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_024943650.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024942386.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015607198.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_015592383.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015594871.1 12 Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_024944042.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015586577.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024942160.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_024936865.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_015591810.1 5 KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336;MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-6798695 "Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation" XP_015587362.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_024943108.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024945624.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204 "Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)" XP_024936640.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_015608440.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_024944903.1 7 MetaCyc: PWY-4702;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25 "Phytate degradation I";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system" XP_015609582.1 6 KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-5497 "Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)" XP_015595611.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015598897.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751 "Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity" XP_024943102.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015584905.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015605304.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024939578.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015608167.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024947652.1 13 Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485 "FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ion homeostasis";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis" XP_015595634.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_015586603.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015595549.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015586568.1 11 Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-167161 "RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation" XP_015589316.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024946911.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024946172.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER" XP_015607816.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_024942410.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015607109.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024940281.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_015586775.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_024946735.1 4 KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;MetaCyc: PWY-8026;Reactome: R-HSA-6807062 "Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol" XP_024936209.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024936220.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015597840.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015604168.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015609418.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation" XP_024936732.1 3 KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857 "Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis" XP_024944385.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015596006.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024936434.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555 "Purine metabolism";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events" XP_015589509.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015608259.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024946840.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_024937394.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015605732.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_015587342.1 4 KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" XP_024943643.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_024946276.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015595685.1 4 MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4 "Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis" XP_015601064.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_015610327.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015591640.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport" XP_015607194.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015586869.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361 "Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_015607624.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024937523.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_015586652.1 9 Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_015586843.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015594462.2 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-606279 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_015605147.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024943957.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015590920.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_015594701.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015603503.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024935824.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024941173.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_015605919.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_015584925.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_024941063.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_024946592.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015599833.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015592868.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_015602408.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_024945756.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015593798.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-9013973 "TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7" XP_024943270.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015586320.1 17 Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-174437;Reactome: R-HSA-5696400 "Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER" XP_024942425.1 24 Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-392451 "Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma" XP_024945261.1 21 Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7219;MetaCyc: PWY-7176 "Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis" XP_024936332.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015608513.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_015607675.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015590231.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024937770.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024943678.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024939041.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024940181.1 9 KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015594248.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_015596714.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015601368.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015597541.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946 "Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants" XP_015597846.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015608383.1 57 Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858 "Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"UCH proteinases";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity" XP_015591572.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024936141.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015589494.1 4 Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" XP_015591743.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024946037.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_024940977.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_015607250.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" YP_002889389.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015589423.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_015607500.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_024943436.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate" XP_015589033.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "DNA replication initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_024946887.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_015605290.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_015588789.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_024942602.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_024946118.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015592323.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418594 "PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events" XP_015605814.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_024947511.1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723 "Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of PTEN mRNA translation" XP_015600764.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_015599185.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015607280.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024938338.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_024943296.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024938933.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_015605413.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024941663.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015606467.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015597747.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_024942605.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015589942.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-167152;Reactome: R-HSA-167238 "Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation" XP_024938780.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024940554.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015598323.1 6 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_015607508.1 8 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_015586471.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_024946001.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015587679.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_015602441.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling" XP_015607740.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024936706.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942 "Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism" XP_015607679.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015587413.1 9 Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_015599603.1 9 MetaCyc: PWY-6703;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-6147;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6983 "Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis" XP_015602967.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015605401.1 3 MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K" XP_015587071.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_024945663.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_024942412.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015586560.1 10 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Activation of AMPK downstream of NMDARs" XP_015606105.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015592270.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024944461.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015604875.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015597105.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015597588.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_015592372.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015587511.1 20 MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis" XP_015605834.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_024943488.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015600823.1 15 Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756 "Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation" XP_015600140.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015600319.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_015603913.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_024936764.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015608452.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015598916.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788 "TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling" XP_024942062.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024942080.1 9 Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790 "TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer" XP_015594002.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015600242.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024945166.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024938169.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_015605616.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015604734.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015587143.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015597901.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation" XP_024946738.1 4 Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062 "Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol" XP_024940493.1 5 KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407 "Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_015584833.1 52 Reactome: R-HSA-73780;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-113418;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-73980;Reactome: R-HSA-6803529;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-1834949;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-9018519 "RNA Polymerase III Chain Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Cytosolic sensors of pathogen-associated DNA";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression" XP_015596451.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015588918.1 14 Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-6798695;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-1474228;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Neutrophil degranulation";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Degradation of the extracellular matrix";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_024947678.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_015603968.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_024936761.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015605761.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_015600783.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015586270.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015602493.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_024944488.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015603947.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_015595158.1 8 MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism" XP_015593067.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024947628.1 5 Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841 "Metabolism of folate and pterines";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate transformations II (plants)" XP_015594041.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_015605778.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015604351.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024944895.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015590853.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_024937949.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024945159.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_015594330.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015605372.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024946871.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_024943441.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_015585700.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_015602157.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015597853.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389960 "Folding of actin by CCT/TriC";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC" XP_015586274.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_024939014.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024943350.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_024945037.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015602540.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015605412.1 30 Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-69231;Reactome: R-HSA-2894862;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-917937;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-2644606;Reactome: R-HSA-2871837;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764 "SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Neddylation";"Prolactin receptor signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Iron uptake and transport";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FCERI mediated NF-kB activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling" XP_024943489.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015588740.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_024945244.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015585675.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015593181.1 26 Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-5617472;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-1234158;Reactome: R-HSA-381340 "Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Attenuation phase";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation" XP_015598138.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_015588928.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_024947404.1 42 Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-110330 "Meiotic synapsis";"HDACs deacetylate histones";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HCMV Late Events";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Packaging Of Telomere Ends";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_024944664.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024943743.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015587974.1 9 KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-196780 "Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Biotin transport and metabolism" XP_015592825.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015601778.1 33 Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638 "SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins" XP_024935582.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015605063.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_024941167.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_015594346.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015596893.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_015599437.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_024941130.1 6 Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-76005 "WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+" XP_015605936.1 12 MetaCyc: PWY-6683;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4 "Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Selenocompound metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenate reduction";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfur metabolism";"Purine metabolism" XP_015604296.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400 "Fanconi Anemia Pathway";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER" XP_015601218.1 4 Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8856828 "Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis" XP_024937831.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_024941100.1 3 Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis" XP_015586913.1 12 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25 "HS-GAG degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"Neutrophil degranulation";"Other glycan degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_015589036.1 2 Reactome: R-HSA-1433559;Reactome: R-HSA-8951664 "Regulation of KIT signaling";"Neddylation" XP_015598707.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024936457.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_015608742.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015595524.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_015605733.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_015584691.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_015604409.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015588420.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_024945830.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_015598307.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_015609085.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_015608717.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015600769.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015596742.1 5 MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24 "Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_024947548.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_015599228.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015602207.2 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015603227.1 4 KEGG: 00500+3.1.3.9;KEGG: 00052+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.9 "Starch and sucrose metabolism";"Galactose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis" XP_015608885.1 3 Reactome: R-HSA-382556;Reactome: R-HSA-5678771;Reactome: R-HSA-1989781 "ABC-family proteins mediated transport";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"PPARA activates gene expression" XP_015601586.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015592606.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015596435.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015589670.1 26 Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276 "Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_015607750.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_015590101.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015588769.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015607601.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015601222.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_015596066.1 14 Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;Reactome: R-HSA-434316;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-500657;Reactome: R-HSA-112043;Reactome: R-HSA-399997;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-418217;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052 "Ca2+ pathway";"Phosphatidylinositol signaling system";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Presynaptic function of Kainate receptors";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_015605291.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_015594455.1 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I" XP_015605374.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015595707.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015600360.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015589966.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024943020.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_024943508.1 15 Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693571 "Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)" XP_024939395.1 12 Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_024941075.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015603508.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024937694.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" XP_024943674.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024944636.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015600262.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_015604836.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015587773.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_015591246.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_024940729.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024938493.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015594343.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328 "SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_015609523.1 26 Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276 "COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_015593461.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_024947544.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024946841.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024947085.1 7 MetaCyc: PWY-4302;MetaCyc: PWY-6692;Reactome: R-HSA-611105;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;MetaCyc: PWY-5083 "Aerobic respiration III (alternative oxidase pathway)";"Fe(II) oxidation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Complex I biogenesis";"NAD/NADH phosphorylation and dephosphorylation" XP_015600437.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_024946623.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_015590392.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015605873.1 11 Reactome: R-HSA-9013957;Reactome: R-HSA-5213460;Reactome: R-HSA-5218900;Reactome: R-HSA-69416;Reactome: R-HSA-3371378;Reactome: R-HSA-75157;Reactome: R-HSA-5357786;Reactome: R-HSA-2562578;Reactome: R-HSA-140534;Reactome: R-HSA-75158;Reactome: R-HSA-933543 "TLR3-mediated TICAM1-dependent programmed cell death";"RIPK1-mediated regulated necrosis";"CASP8 activity is inhibited";"Dimerization of procaspase-8";"Regulation by c-FLIP";"FasL/ CD95L signaling";"TNFR1-induced proapoptotic signaling";"TRIF-mediated programmed cell death";"Caspase activation via Death Receptors in the presence of ligand";"TRAIL signaling";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10" XP_015593522.1 7 Reactome: R-HSA-2029485;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4 "Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Synthesis of PG";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Ether lipid metabolism" XP_024941230.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024941791.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024937981.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015587436.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024941611.1 4 Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism" XP_015607476.1 10 MetaCyc: PWY-6361;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_015596953.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_015588640.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_024946005.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_024945875.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs" XP_015600169.1 6 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures" XP_015585500.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024940956.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357 "Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1" XP_015588071.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015602676.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015593372.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015601672.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_024942280.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024942108.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling" XP_024942397.1 6 KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Galactose metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" XP_015596700.1 7 Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10 "Pyrimidine biosynthesis";"UMP biosynthesis I";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism" XP_015584908.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_015591094.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015591284.1 2 KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19 "Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism" XP_015605454.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015595298.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015589318.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015587653.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015592600.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024941904.1 4 Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_015595673.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015592358.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015597015.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024936156.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024944894.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024943047.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_015589802.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015597076.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024944081.1 33 Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453 "Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response" XP_015597641.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_024944365.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024942630.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015595184.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_015589220.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024945592.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015585869.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_024945254.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015595824.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015609888.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751 "Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated" XP_015604625.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024947762.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015603120.2 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_015589470.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids" XP_015610119.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015592814.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_015588992.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015591886.1 5 Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;MetaCyc: PWY-7204;MetaCyc: PWY-7282 "Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_024942205.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015591183.1 22 Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated" XP_015598083.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015603957.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015602899.1 39 Reactome: R-HSA-5654228;Reactome: R-HSA-5654704;Reactome: R-HSA-5654688;Reactome: R-HSA-5654221;Reactome: R-HSA-2033514;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-190375;Reactome: R-HSA-5654720;Reactome: R-HSA-2219530;Reactome: R-HSA-5658623;Reactome: R-HSA-1839130;Reactome: R-HSA-5654732;Reactome: R-HSA-190373;Reactome: R-HSA-5654706;Reactome: R-HSA-5654227;Reactome: R-HSA-190372;Reactome: R-HSA-5654710;Reactome: R-HSA-190322;Reactome: R-HSA-5654689;Reactome: R-HSA-8853338;Reactome: R-HSA-1839122;Reactome: R-HSA-2033519;Reactome: R-HSA-5654699;Reactome: R-HSA-5654219;Reactome: R-HSA-5655253;Reactome: R-HSA-5654700;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-5654695;Reactome: R-HSA-5654687;Reactome: R-HSA-5654733;Reactome: R-HSA-5655302;Reactome: R-HSA-5654693;Reactome: R-HSA-5654726;Reactome: R-HSA-5654727;Reactome: R-HSA-190371;Reactome: R-HSA-5654719;Reactome: R-HSA-5654712 "Phospholipase C-mediated cascade, FGFR4";"SHC-mediated cascade:FGFR3";"SHC-mediated cascade:FGFR1";"Phospholipase C-mediated cascade, FGFR2";"FGFR3 mutant receptor activation";"PIP3 activates AKT signaling";"PI3K Cascade";"FGFR2c ligand binding and activation";"PI-3K cascade:FGFR4";"Constitutive Signaling by Aberrant PI3K in Cancer";"FGFRL1 modulation of FGFR1 signaling";"Signaling by activated point mutants of FGFR3";"Negative regulation of FGFR3 signaling";"FGFR1c ligand binding and activation";"FRS-mediated FGFR3 signaling";"Phospholipase C-mediated cascade, FGFR3";"FGFR3c ligand binding and activation";"PI-3K cascade:FGFR3";"FGFR4 ligand binding and activation";"PI-3K cascade:FGFR1";"Signaling by FGFR3 point mutants in cancer";"Signaling by activated point mutants of FGFR1";"Activated point mutants of FGFR2";"SHC-mediated cascade:FGFR2";"Phospholipase C-mediated cascade: FGFR1";"Signaling by FGFR2 in disease";"FRS-mediated FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI-3K cascade:FGFR2";"Downstream signaling of activated FGFR1";"Negative regulation of FGFR4 signaling";"Signaling by FGFR1 in disease";"FRS-mediated FGFR1 signaling";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR2 signaling";"FGFR3b ligand binding and activation";"SHC-mediated cascade:FGFR4";"FRS-mediated FGFR4 signaling" XP_015600320.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015602472.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_024944886.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015585896.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis" XP_024939330.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_024945572.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015609017.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015594676.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015606303.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024936402.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_015596884.1 8 Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665 "Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells" XP_015602189.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_024946351.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024936440.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787 "Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Hedgehog 'off' state" XP_015598437.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015608486.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_015610178.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015610112.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015598659.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015608245.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015595481.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015606974.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174178 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015608676.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080 "Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)" XP_024943005.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_015592917.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162 "HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape" XP_015600483.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015602351.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015585629.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024940253.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_024945496.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015609012.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024944885.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015588951.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_024937105.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015595699.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_015595686.1 4 KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931 "Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_015586687.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015609110.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_015602050.1 2 KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128 "mTOR signaling pathway";"MAPK6/MAPK4 signaling" XP_015605303.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015608613.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015586457.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_024946168.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_015599147.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015607569.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015608278.1 13 Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7198 "Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_015595355.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015596350.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015590011.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015597484.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_015585916.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_015589369.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_015592792.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_015594728.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_015592584.1 17 Reactome: R-HSA-5693616;Reactome: R-HSA-1433557;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-75035;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473 "Presynaptic phase of homologous DNA pairing and strand exchange";"Signaling by SCF-KIT";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"PI3K-Akt signaling pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Activation of ATR in response to replication stress";"Thermogenesis";"Human papillomavirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint" XP_015585804.1 12 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"G alpha (q) signalling events";"Rho GTPase cycle";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK" XP_015602360.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015593901.1 18 Reactome: R-HSA-5685938;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;MetaCyc: PWY-7511;Reactome: R-HSA-6796648;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Protein ubiquitination";"TP53 Regulates Transcription of DNA Repair Genes";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)" XP_015590958.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015601960.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_024936152.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015603145.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_015588868.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024942311.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015598915.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789 "TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs" XP_015587899.1 57 Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5678895 "SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"Degradation of AXIN";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis" XP_015591530.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015593632.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024939399.1 12 Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208 "ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling" XP_024940685.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024942117.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024944189.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015603212.1 10 Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-400206 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha" XP_015591716.1 5 KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667 "Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I" XP_024939387.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024943168.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_015602694.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015585692.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015595698.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015605011.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015599518.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_024942119.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015604051.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015605416.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024937283.1 7 Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500 "TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle" XP_015595082.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024936544.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_024940362.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_015595313.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015589474.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878 "EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-mediated anterograde transport" XP_015603195.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" XP_024941832.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_015598500.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_015602566.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_024936365.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_015593895.1 18 Reactome: R-HSA-6796648;MetaCyc: PWY-7511;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;Reactome: R-HSA-5685938;Reactome: R-HSA-5689901;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214 "TP53 Regulates Transcription of DNA Repair Genes";"Protein ubiquitination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"HDR through Single Strand Annealing (SSA)";"Metalloprotease DUBs";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins" XP_024939969.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167161 "Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation" XP_024944357.1 24 Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-8964315 "G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK" XP_015609720.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_015598579.1 6 KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism" XP_015594337.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015593496.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024939740.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024938809.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015608544.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_015604848.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_024940957.1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine" XP_015600482.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015585768.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_015590394.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024947399.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024944469.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015604112.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024935455.1 6 KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-5514 "Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_015604520.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024944176.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015596982.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782 "Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis" XP_015591196.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024943149.1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568 "ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase" XP_015604416.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167246 "Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_015596997.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_024945358.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion" XP_024938587.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_015605128.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_024939261.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024937446.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015587694.1 4 KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27 "Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism" XP_015600317.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_015597309.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015585173.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_024943115.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015604974.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_024944485.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015586662.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015590822.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_015602193.1 17 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 05163+2.7.11.1;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-174178;Reactome: R-HSA-68877;Reactome: R-HSA-9022692;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Thermogenesis";"Relaxin signaling pathway";"EML4 and NUDC in mitotic spindle formation";"Human cytomegalovirus infection";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Mitotic Prometaphase";"Regulation of MECP2 expression and activity";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway" XP_015602156.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015584915.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015590766.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295 "Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation" XP_024936978.1 22 Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221 "Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Negative regulation of MAPK pathway" XP_015602420.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_015589985.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722 "Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis" XP_015609854.1 22 Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-6811558 "Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_015587663.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_024938850.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_024938586.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_024938360.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015606049.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015591668.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_015609119.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_015602002.1 3 KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639 "Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis" XP_024936527.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_015598231.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_015586499.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015606167.1 3 Reactome: R-HSA-6790901;Reactome: R-HSA-8951664;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015590296.1 3 MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996 "Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)" XP_015587759.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_015585974.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015592299.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_024938257.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_015594349.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015584952.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_015608426.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015595124.1 7 Reactome: R-HSA-983231;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_024940437.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_015599044.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_015592616.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_015608564.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015585876.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015589636.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015597921.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_024937945.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024938967.1 4 KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_015585653.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_015595835.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_024942218.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015587190.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015595775.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_015598653.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015602938.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_015587880.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway" XP_015598180.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-69481 "NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"G2/M Checkpoints" XP_024938356.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024942287.1 3 Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_015595860.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_024937326.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015588136.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024936499.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015594320.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024945814.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_015598227.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167238 "RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation" XP_024944899.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015590974.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024938594.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015607660.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_015594515.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_015608869.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_015605356.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607212.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015591962.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_024938343.1 5 Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695 "Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation" XP_024937858.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015610319.1 5 MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;Reactome: R-HSA-9033500 "Plasmalogen biosynthesis";"Ether lipid metabolism";"Peroxisomal protein import";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins" XP_024944511.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015603325.1 4 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Glycerophospholipid metabolism" XP_015594410.1 16 Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-1660499;Reactome: R-HSA-194840;Reactome: R-HSA-6811558;Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-912631;Reactome: R-HSA-114604 "CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Synthesis of PIPs at the plasma membrane";"Rho GTPase cycle";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-7 signaling";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Regulation of signaling by CBL";"GPVI-mediated activation cascade" XP_015585332.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015586736.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_015600768.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015590558.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024937491.1 5 MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)" XP_015594524.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015597551.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction" XP_015610472.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_015585167.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_015585478.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024947295.1 42 Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427413 "HDACs deacetylate histones";"Meiotic synapsis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"HCMV Late Events";"Amyloid fiber formation";"Packaging Of Telomere Ends";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression" XP_015585404.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_024941229.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024935684.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_024943073.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015597020.1 3 Reactome: R-HSA-5576890;Reactome: R-HSA-1296072;Reactome: R-HSA-5576893 "Phase 3 - rapid repolarisation";"Voltage gated Potassium channels";"Phase 2 - plateau phase" XP_015585681.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015608646.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024937126.1 9 MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-196780 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Biotin transport and metabolism" XP_015595074.1 6 MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_015587611.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_024939574.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015589464.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015591140.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism" XP_024937229.1 10 KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11 "Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Galactose metabolism" XP_024946759.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_024936881.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_015585587.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_024942163.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_015608319.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024940325.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015591366.1 5 Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-532668;MetaCyc: PWY-7918 "Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)" XP_024941019.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_015594772.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015593730.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_015592374.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015599321.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015606216.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015597041.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_024945020.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024937212.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_015598712.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_015590282.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_015585322.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_015593657.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015598356.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015584999.1 56 Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5668541 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway" XP_024945633.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_015603210.1 10 Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538 "MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA" XP_015605447.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_015600522.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015601727.1 6 MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21 "Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism" XP_015603754.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024947760.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015596910.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580 "FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence" XP_024947702.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway" XP_015595663.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_015590437.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_024941303.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_015604725.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024936485.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015605720.1 19 Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-8876725;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-3214858;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Protein methylation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"RMTs methylate histone arginines";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex" XP_024939001.1 8 Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_015605801.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_015605757.1 3 KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate" XP_024937396.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015598676.1 6 MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;MetaCyc: PWY-7442 "Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis" XP_024942757.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9609690 "Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"snRNP Assembly";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events" XP_024941837.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015596421.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024939632.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024947357.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024945250.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_015598672.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024940501.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024944696.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_015601435.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015609527.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015592788.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015592428.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015585691.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015601293.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862 "RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_015596238.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015603142.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015609842.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_015604245.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766 "Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown" XP_024936719.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015603314.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_015589268.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015607213.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024939339.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-202433;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules";"Regulation of actin dynamics for phagocytic cup formation" XP_015586285.1 11 Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670 "Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway" XP_024936447.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_015600591.1 14 MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5108;MetaCyc: PWY-5078;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5104;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;KEGG: 00966+2.6.1.42 "L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation III";"L-isoleucine biosynthesis V";"L-isoleucine degradation II";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"Glucosinolate biosynthesis" XP_024937434.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024942373.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_015604516.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015595734.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015605069.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_015595785.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_015599690.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015603710.1 3 KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685 "Pyrimidine metabolism";"Purine metabolism";"Detoxification of Reactive Oxygen Species" XP_015585807.1 12 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482 "Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"NRAGE signals death through JNK";"Relaxin signaling pathway";"G alpha (q) signalling events";"Rho GTPase cycle";"Human cytomegalovirus infection";"Human papillomavirus infection";"G alpha (12/13) signalling events" XP_015591467.1 40 KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7216;MetaCyc: PWY-5789;MetaCyc: PWY-6944;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-7779;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-7401;MetaCyc: PWY-6863;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6945;KEGG: 00623+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7656;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00362+4.2.1.17+1.1.1.35 "Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Androstenedione degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Limonene and pinene degradation";"Pyruvate fermentation to butanol II (engineered)";"Methyl tert-butyl ether degradation";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid degradation";"Fatty acid salvage";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Toluene degradation";"Benzoyl-coa degradation I (aerobic)";"Spodoptera littoralis pheromone biosynthesis";"Lysine degradation";"Pyruvate fermentation to butanol I";"Butanoate metabolism";"Propanoate metabolism";"2-methylpropene degradation";"Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Caprolactam degradation";"Geraniol degradation";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Aminobenzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoate degradation" XP_015603279.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015599337.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_024937933.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015595842.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041 "Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_024946889.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_015603170.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_015593495.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015589192.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015607464.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015606485.1 3 Reactome: R-HSA-2514859;Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60 "Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation";"Lysine degradation" XP_015609236.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024939669.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_015597953.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015609510.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_024938810.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015602806.1 19 Reactome: R-HSA-4420097;Reactome: R-HSA-8964616;Reactome: R-HSA-418885;Reactome: R-HSA-5663213;Reactome: R-HSA-389359;Reactome: R-HSA-428543;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-182971;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5687128;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-114604 "VEGFA-VEGFR2 Pathway";"G beta:gamma signalling through CDC42";"DCC mediated attractive signaling";"RHO GTPases Activate WASPs and WAVEs";"CD28 dependent Vav1 pathway";"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"EGFR downregulation";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"MAPK6/MAPK4 signaling";"Myogenesis";"RHO GTPases Activate Formins";"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"GPVI-mediated activation cascade" XP_024937401.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024939218.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015595570.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_015590073.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015603911.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_015605696.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_015607414.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015591175.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015600125.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_024940492.1 5 Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling" XP_015600822.1 15 Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939 "Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)" XP_015588597.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy" XP_015592381.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_015586733.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_015584664.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_015602216.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_015585933.1 14 Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167158 "Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex" XP_015600884.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511 "Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination" XP_015587253.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria" XP_024940495.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015599921.1 16 Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-166058;Reactome: R-HSA-5602498;Reactome: R-HSA-975871;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-975155;Reactome: R-HSA-6811558;Reactome: R-HSA-5603037;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-1810476;Reactome: R-HSA-1257604;Reactome: R-HSA-975138;Reactome: R-HSA-5602680 "IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 dependent cascade initiated on endosome";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR5)";"ER-Phagosome pathway";"Interleukin-1 signaling";"RIP-mediated NFkB activation via ZBP1";"PIP3 activates AKT signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR5)" XP_024936745.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_015595924.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024940483.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_015602347.1 7 Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1 "Signaling by Retinoic Acid";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_015585753.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024936098.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_024941539.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_015592377.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024939116.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_015599637.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015585463.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015598783.1 13 Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-9645460 "Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway" XP_015585540.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024942508.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015600942.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_024943107.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015602238.1 12 MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053 "Anandamide biosynthesis I";"Ether lipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II" XP_015607159.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024941894.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015592400.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015601411.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015593949.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024939539.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015609177.1 9 Reactome: R-HSA-70263;MetaCyc: PWY-7003;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis" XP_024943131.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_015598360.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_015604203.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-1268020 "Processing of SMDT1";"Mitochondrial protein import" XP_015609818.1 6 Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10 "Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_015596920.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_015597669.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_015608636.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015596834.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015585955.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024947229.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024946830.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_015593271.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015601851.1 6 KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23 "Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Glycosaminoglycan degradation" XP_015604521.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015608102.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015599903.1 4 KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"UCH proteinases" XP_015593357.1 9 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)" XP_015595548.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015584918.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015601209.1 4 KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_015590444.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy" XP_015599085.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_024945781.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_015584834.1 52 Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-5578749 "RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs" XP_024947268.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015598662.1 6 MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2 "ATP biosynthesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Cristae formation";"Oxidative phosphorylation" XP_024937042.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_024941104.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015586779.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024935973.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015595440.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_015598461.1 8 KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901 "Cysteine and methionine metabolism";"Pyruvate metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Superpathway of glucose and xylose degradation" XP_024939882.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015590420.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_015606112.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_024938754.1 6 MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_024940447.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_015607171.1 10 MetaCyc: PWY-7344;MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7328;Reactome: R-HSA-5609977 "UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)" XP_024939489.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_024945104.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024944538.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_024937248.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_015586534.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015588824.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015600825.1 15 Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_024945648.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024937331.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024944661.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015601993.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1" XP_024945647.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015597512.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_015599279.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_015588787.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" XP_015589979.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_015600665.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis" XP_015607652.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_015597016.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015594733.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_024942836.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_024937763.1 3 Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation" XP_024941071.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015587820.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_024939537.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024936239.1 8 KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism" XP_015602709.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_015595831.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015587425.1 32 Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-112382 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of RNA Pol II elongation complex" XP_024938012.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015595764.2 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_015584787.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_024938971.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024940863.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015597902.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation" XP_024938240.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015585889.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015592618.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_024935892.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015596637.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024944925.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_024944434.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_024941224.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015610224.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_015593904.1 3 Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361 "Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins" XP_024945634.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_024943517.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015584778.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015608258.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015598155.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_015603161.1 3 KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)" XP_015600750.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749 "SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transcriptional regulation by small RNAs" XP_024947090.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015602949.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015590285.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6" XP_015603417.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015597718.1 4 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_024939278.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024935667.1 2 Reactome: R-HSA-167827;Reactome: R-HSA-167826 "The proton buffering model";"The fatty acid cycling model" XP_024939277.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_015604911.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015596722.1 9 Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475 "HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_015594252.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_015603463.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024938438.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015610231.1 6 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_024943169.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_015596311.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_015594351.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015596281.1 16 Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128 "Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling" XP_015594532.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015592370.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024937416.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015585498.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024936789.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015587231.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015607840.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_015588975.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015591673.1 13 KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7227 "Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_015585585.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_015595956.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-141430 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_015598954.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription" XP_024939493.1 4 MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" XP_024938369.1 4 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17 "Glycerol degradation I";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions" XP_024935693.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_024938331.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_015607839.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_015604901.1 6 Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648 "Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes" XP_015590556.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015601376.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015595701.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_015595628.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_015592872.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)" XP_015609227.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024947650.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809 "CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization" XP_024941971.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_015592315.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_024942844.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015602237.1 12 KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4 "Ether lipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism" XP_015588108.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015609481.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015603071.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015586868.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024941395.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-3232118;Reactome: R-HSA-5693565;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of transcription factors";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint" XP_024944602.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024939747.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024943297.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024936497.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024937894.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_024938159.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_015610118.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015602855.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-442720 "Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_015599291.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015593508.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015598139.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_015586004.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015607871.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_015585686.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015584942.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_015586175.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024946575.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024936546.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015603124.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_024945490.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024947476.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024944370.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015590775.1 11 Reactome: R-HSA-1632852;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599 "Macroautophagy";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases" XP_015597981.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6798695 "Fanconi Anemia Pathway";"Neutrophil degranulation" XP_024937747.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015604368.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024939336.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015605347.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015591282.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015599899.1 3 Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_024943166.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_015604683.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2 "Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism" XP_015602450.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015593143.1 18 MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166 "Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Ether lipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Synthesis of PA" XP_015607479.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes" XP_015604892.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_024940178.1 9 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_015591586.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_015595335.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_024938923.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015595384.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015599647.1 30 Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-2564830;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Cytosolic iron-sulfur cluster assembly";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation" XP_015586706.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_015595823.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024942232.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015609016.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015600775.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_015589479.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase" XP_015599566.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024944644.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-2219530 "PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_015602746.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015603568.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015596670.1 5 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_024942279.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015584795.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015593524.1 7 Reactome: R-HSA-2029485;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561 "Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Glycerophospholipid metabolism";"Synthesis of PG";"Ether lipid metabolism";"Choline biosynthesis III" XP_024936508.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015597030.1 5 Reactome: R-HSA-168638;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-171007 "NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"DSCAM interactions";"p38MAPK events" XP_015594590.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_024939742.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015588999.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_015597018.1 3 Reactome: R-HSA-1296072;Reactome: R-HSA-5576890;Reactome: R-HSA-5576893 "Voltage gated Potassium channels";"Phase 3 - rapid repolarisation";"Phase 2 - plateau phase" XP_015607054.1 10 Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;MetaCyc: PWY-7849;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;Reactome: R-HSA-977225;Reactome: R-HSA-3000171 "Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Retinoid metabolism and transport";"Neutrophil degranulation";"Urate conversion to allantoin I";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions" XP_024941247.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015597548.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6798695 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"Neutrophil degranulation" XP_015596114.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-2160916 "AURKA Activation by TPX2";"Hyaluronan uptake and degradation" XP_024935832.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_024942288.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938 "Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)" XP_015585867.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_024946822.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_015605195.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024940646.1 10 Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-2871837 "Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Neddylation";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation" XP_024943954.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_015601757.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015599408.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_015601055.1 8 Reactome: R-HSA-191273;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391 "Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" XP_024938878.1 8 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;Reactome: R-HSA-5173105 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"O-linked glycosylation" XP_015590611.1 7 KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-7158;MetaCyc: PWY-6134 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylketonuria";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV" XP_024939541.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_024942095.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015586600.1 14 Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-9634638 "EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_024944242.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_024945243.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024943777.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418594 "PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events" XP_024947262.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024937762.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015592876.1 6 MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168 "Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)" XP_015589178.1 7 MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Pentose phosphate pathway" XP_024945685.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607281.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024943857.1 179 Reactome: R-HSA-180585;Reactome: R-HSA-936440;Reactome: R-HSA-179409;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-450302;Reactome: R-HSA-5689603;Reactome: R-HSA-6804756;Reactome: R-HSA-201681;Reactome: R-HSA-156902;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-937042;Reactome: R-HSA-174184;Reactome: R-HSA-5205685;Reactome: R-HSA-8856828;Reactome: R-HSA-975110;Reactome: R-HSA-168928;Reactome: R-HSA-5687128;Reactome: R-HSA-9013973;Reactome: R-HSA-209543;Reactome: R-HSA-2173788;Reactome: R-HSA-8941858;Reactome: R-HSA-209560;Reactome: R-HSA-5362768;Reactome: R-HSA-2173795;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-445989;Reactome: R-HSA-2894862;Reactome: R-HSA-69231;Reactome: R-HSA-4641263;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-3134975;Reactome: R-HSA-5654727;Reactome: R-HSA-174490;Reactome: R-HSA-5689896;Reactome: R-HSA-110320;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-8856825;Reactome: R-HSA-9013507;Reactome: R-HSA-1236974;Reactome: R-HSA-9636383;Reactome: R-HSA-192823;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-1799339;Reactome: R-HSA-2559580;Reactome: R-HSA-9033241;Reactome: R-HSA-5696395;Reactome: R-HSA-8863795;Reactome: R-HSA-1169408;Reactome: R-HSA-5654732;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-72764;Reactome: R-HSA-168927;Reactome: R-HSA-2173796;Reactome: R-HSA-2122948;Reactome: R-HSA-4641258;Reactome: R-HSA-2979096;Reactome: R-HSA-975957;Reactome: R-HSA-1358803;Reactome: R-HSA-69017;Reactome: R-HSA-2691232;Reactome: R-HSA-6782210;Reactome: R-HSA-9615710;Reactome: R-HSA-174178;Reactome: R-HSA-5693607;Reactome: R-HSA-1236382;Reactome: R-HSA-5658442;Reactome: R-HSA-72706;Reactome: R-HSA-5654726;Reactome: R-HSA-532668;Reactome: R-HSA-6791226;Reactome: R-HSA-2871837;Reactome: R-HSA-2559585;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-72689;Reactome: R-HSA-8948751;Reactome: R-HSA-6782135;Reactome: R-HSA-9637628;Reactome: R-HSA-400253;Reactome: R-HSA-5607761;Reactome: R-HSA-5696394;Reactome: R-HSA-5656121;Reactome: R-HSA-5676590;Reactome: R-HSA-5689901;Reactome: R-HSA-9613829;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-983168;Reactome: R-HSA-6804760;Reactome: R-HSA-6783310;Reactome: R-HSA-937072;Reactome: R-HSA-6804757;Reactome: R-HSA-2559582;Reactome: R-HSA-382556;Reactome: R-HSA-5656169;Reactome: R-HSA-168638;Reactome: R-HSA-977225;Reactome: R-HSA-5668541;Reactome: R-HSA-8849469;Reactome: R-HSA-937039;Reactome: R-HSA-174084;Reactome: R-HSA-156827;Reactome: R-HSA-9646399;Reactome: R-HSA-174154;Reactome: R-HSA-2122947;Reactome: R-HSA-8939902;Reactome: R-HSA-8876493;Reactome: R-HSA-9010553;Reactome: R-HSA-162588;Reactome: R-HSA-69541;Reactome: R-HSA-5696397;Reactome: R-HSA-2408557;Reactome: R-HSA-182971;Reactome: R-HSA-1253288;Reactome: R-HSA-110314;Reactome: R-HSA-5654733;Reactome: R-HSA-8875360;Reactome: R-HSA-975956;Reactome: R-HSA-8948747;Reactome: R-HSA-180534;Reactome: R-HSA-2672351;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-937041;Reactome: R-HSA-8866652;Reactome: R-HSA-187577;Reactome: R-HSA-917937;Reactome: R-HSA-5689877;Reactome: R-HSA-1169091;Reactome: R-HSA-975144;Reactome: R-HSA-2644606;Reactome: R-HSA-912631;Reactome: R-HSA-5675221;Reactome: R-HSA-3769402;Reactome: R-HSA-5696400;Reactome: R-HSA-9014325;Reactome: R-HSA-901032;Reactome: R-HSA-5607764;Reactome: R-HSA-174048;Reactome: R-HSA-9645460;Reactome: R-HSA-5610780;Reactome: R-HSA-2173791;Reactome: R-HSA-110312;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-6781823;Reactome: R-HSA-936964;Reactome: R-HSA-8866654;Reactome: R-HSA-205043;Reactome: R-HSA-211733;Reactome: R-HSA-5675482;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9633012;Reactome: R-HSA-5685942;Reactome: R-HSA-5357905;Reactome: R-HSA-69481;Reactome: R-HSA-5684264;Reactome: R-HSA-5678895;Reactome: R-HSA-175474;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-3322077;Reactome: R-HSA-5655862;Reactome: R-HSA-1295596;Reactome: R-HSA-5693565;Reactome: R-HSA-3785653 "Vif-mediated degradation of APOBEC3G";"Negative regulators of DDX58/IFIH1 signaling";"APC-Cdc20 mediated degradation of Nek2A";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"activated TAK1 mediates p38 MAPK activation";"UCH proteinases";"Regulation of TP53 Activity through Phosphorylation";"TCF dependent signaling in response to WNT";"Peptide chain elongation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"IRAK2 mediated activation of TAK1 complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Pink/Parkin Mediated Mitophagy";"Clathrin-mediated endocytosis";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"MAPK6/MAPK4 signaling";"TICAM1-dependent activation of IRF3/IRF7";"p75NTR recruits signalling complexes";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX3 expression and activity";"NF-kB is activated and signals survival";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Cyclin D associated events in G1";"Regulation of FZD by ubiquitination";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of FGFR2 signaling";"Membrane binding and targetting of GAG proteins";"Ovarian tumor domain proteases";"Translesion Synthesis by POLH";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cargo recognition for clathrin-mediated endocytosis";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"ER-Phagosome pathway";"Prevention of phagosomal-lysosomal fusion";"Viral mRNA Translation";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"SRP-dependent cotranslational protein targeting to membrane";"Oxidative Stress Induced Senescence";"Peroxisomal protein import";"Formation of Incision Complex in GG-NER";"Downregulation of ERBB2 signaling";"ISG15 antiviral mechanism";"Negative regulation of FGFR3 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Eukaryotic Translation Termination";"TICAM1, RIP1-mediated IKK complex recruitment";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of DVL";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Downregulation of ERBB2:ERBB3 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Late endosomal microautophagy";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Processing of DNA double-strand break ends";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of RAS by GAPs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Negative regulation of FGFR1 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Major pathway of rRNA processing in the nucleolus and cytosol";"FCERI mediated NF-kB activation";"Oncogene Induced Senescence";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Formation of a pool of free 40S subunits";"Regulation of PTEN stability and activity";"Dual incision in TC-NER";"Modulation by Mtb of host immune system";"Circadian Clock";"Dectin-1 mediated noncanonical NF-kB signaling";"DNA Damage Recognition in GG-NER";"Translesion synthesis by POLI";"NIK-->noncanonical NF-kB signaling";"Metalloprotease DUBs";"Chaperone Mediated Autophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of TP53 Activity through Methylation";"Fanconi Anemia Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of TP53 Degradation";"Senescence-Associated Secretory Phenotype (SASP)";"ABC-family proteins mediated transport";"Termination of translesion DNA synthesis";"NOD1/2 Signaling Pathway";"Amyloid fiber formation";"TNFR2 non-canonical NF-kB pathway";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"IRAK1 recruits IKK complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"L13a-mediated translational silencing of Ceruloplasmin expression";"Aggrephagy";"APC/C:Cdc20 mediated degradation of Securin";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX2 expression and activity";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of expression of SLITs and ROBOs";"Budding and maturation of HIV virion";"Stabilization of p53";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Selenocysteine synthesis";"EGFR downregulation";"Downregulation of ERBB4 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Negative regulation of FGFR4 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of PTEN localization";"Vpu mediated degradation of CD4";"Stimuli-sensing channels";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"IKK complex recruitment mediated by RIP1";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"SCF(Skp2)-mediated degradation of p27/p21";"Iron uptake and transport";"Josephin domain DUBs";"Activation of NF-kappaB in B cells";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of signaling by CBL";"Negative regulation of MAPK pathway";"Deactivation of the beta-catenin transactivating complex";"Dual Incision in GG-NER";"TICAM1,TRAF6-dependent induction of TAK1 complex";"ER Quality Control Compartment (ERQC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Alpha-protein kinase 1 signaling pathway";"Degradation of GLI1 by the proteasome";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Translesion synthesis by REV1";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Formation of TC-NER Pre-Incision Complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"E3 ubiquitin ligases ubiquitinate target proteins";"NRIF signals cell death from the nucleus";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of necroptotic cell death";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"HDR through Homologous Recombination (HRR)";"Regulation of TNFR1 signaling";"G2/M Checkpoints";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Defective CFTR causes cystic fibrosis";"Assembly Of The HIV Virion";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Glycogen synthesis";"Translesion synthesis by POLK";"Spry regulation of FGF signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myoclonic epilepsy of Lafora" XP_015598286.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_015602524.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins" XP_015591333.1 13 Reactome: R-HSA-2871809;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-202433;Reactome: R-HSA-2871796;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2029485;MetaCyc: PWY-6351;MetaCyc: PWY-6367 "FCERI mediated Ca+2 mobilization";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Generation of second messenger molecules";"FCERI mediated MAPK activation";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism" XP_024935934.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024939715.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024942775.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015601320.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015610194.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015597701.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024942764.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024942928.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024946020.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_015608014.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015589801.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015597550.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction" XP_015608789.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_024941004.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024942498.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_015605192.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024939317.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015603612.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024947557.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024936357.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024937335.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015589453.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_024937941.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024938849.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015589943.1 40 Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-6803529 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"FGFR2 alternative splicing" XP_015609524.1 26 Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024943732.1 3 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_015587461.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015607676.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015585346.1 8 MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "ATP biosynthesis";"Photosynthesis";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_015587083.1 14 Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944 "Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2" XP_024947488.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015605813.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_015587718.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Activation of RAC1";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_015595135.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_024946698.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_015609689.1 4 MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_015607220.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_024938813.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_015595925.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_015591806.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes" XP_015587460.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015602168.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024942372.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_024943344.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015592012.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_015609578.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015590946.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024944335.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015586574.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024942710.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015594003.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015601409.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015600808.2 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_015601437.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024945023.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_024947254.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024943847.1 16 Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955 "Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation" XP_015607598.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015591539.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015592692.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015607055.1 10 MetaCyc: PWY-5691;Reactome: R-HSA-3000171;Reactome: R-HSA-977225;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;KEGG: 00230+3.5.2.17;Reactome: R-HSA-6798695;Reactome: R-HSA-975634;MetaCyc: PWY-7849 "Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"Amyloid fiber formation";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Purine metabolism";"Neutrophil degranulation";"Retinoid metabolism and transport";"Urate conversion to allantoin III" XP_024940185.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024936427.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_024942157.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_024939264.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_015603478.1 4 KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol" XP_015594864.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_015598660.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015588984.1 13 KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-7821;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00230+3.6.1.66 "Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Purine catabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Purine metabolism" XP_015595655.1 17 Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-202424 "Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ca2+ pathway";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling" XP_015598351.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024940896.1 13 KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857 "Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Keratan sulfate degradation" XP_024945976.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_024938227.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Ion homeostasis" XP_015608781.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015594768.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024944343.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015601916.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_024940864.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024942807.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300 "Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors" XP_024942149.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024938805.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015586744.1 6 Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654693 "FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling" XP_015587719.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015597506.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_024944356.1 24 Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_015610410.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_024936615.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_024941489.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015603148.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_015599682.1 19 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"Chylomicron remodeling";"Chylomicron clearance";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"LDL remodeling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"VLDL assembly";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class A Receptors" XP_024939706.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024947822.1 8 Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750 "Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6" XP_024935898.1 14 Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-174411 "PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere" XP_024943803.1 3 KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271 "Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_015591676.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024943484.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015606018.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015597861.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_015602492.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_015589872.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_024941747.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015608360.1 4 KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603 "Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine" XP_015601840.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024945436.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_015607691.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015602789.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" YP_002889388.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015589422.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_015595092.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024938404.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_015602150.1 7 Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598 "TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"PCP/CE pathway";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins" XP_015589910.1 6 Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52 "Serine biosynthesis";"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_024939577.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_024941575.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015589799.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015601519.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_024945331.1 3 KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate" XP_015596433.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787 "Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Hedgehog 'off' state" XP_015593165.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024946587.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_015593850.1 18 KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7198 "Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_024939400.1 12 Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015585194.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_015608747.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_024940645.1 10 Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264 "Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation" XP_024939279.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015596197.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015605948.1 16 Reactome: R-HSA-1257604;Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530 "PIP3 activates AKT signaling";"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_024942239.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024940630.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_015605123.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015602708.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_015590852.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_015596952.1 6 MetaCyc: PWY-6906;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210 "Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine" XP_024943251.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_015601603.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_015608009.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015585268.1 3 KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857 "Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis" XP_015589325.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015586594.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108 "RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_015610399.1 8 MetaCyc: PWY-6611;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826 "Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Surfactant metabolism" XP_024936481.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461 "Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation" XP_024941223.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015593328.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994 "ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_024942332.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024945967.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015595076.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004 "Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity" XP_024946818.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_015610114.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_024944462.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015600805.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015604951.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015604512.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024937934.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015603305.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_024946933.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_015606892.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015589594.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_015589599.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Ion homeostasis" XP_015593398.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464 "Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins" XP_015592617.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_015599606.1 9 KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-6147 "Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I" XP_015597197.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015609742.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_015587761.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" YP_002889384.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024937239.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015603437.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024945434.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-4608870;Reactome: R-HSA-8856828;Reactome: R-HSA-5340588;Reactome: R-HSA-373080;Reactome: R-HSA-8856825;Reactome: R-HSA-4641263;Reactome: R-HSA-4086398 "WNT5A-dependent internalization of FZD4";"Asymmetric localization of PCP proteins";"Clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Class B/2 (Secretin family receptors)";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Ca2+ pathway" XP_015586638.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_024938365.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015600265.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" XP_015600407.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015591641.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768 "ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_015596496.1 4 KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_015599691.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_024936074.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024946033.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015589319.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015602749.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024946499.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015585786.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015604755.1 4 Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889 "ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes" XP_015590808.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015584889.1 2 Reactome: R-HSA-196299;Reactome: R-HSA-4641262 "Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_015590504.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015589460.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690 "Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events" XP_015593809.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015587593.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015606054.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024943478.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_024947638.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024938055.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015609124.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015600359.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015590962.1 3 KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_024938887.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015605478.1 57 Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-69481 "Neutrophil degranulation";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints" XP_024947559.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024943130.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_015586610.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_015589298.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_015587014.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015587830.1 5 KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate" XP_015597665.1 13 Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101 "Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation" XP_024944565.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_024943226.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689 "Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_015587313.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024940602.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024937076.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_024943823.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_024942168.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024946809.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015596549.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024935967.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015589807.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024935742.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_015592476.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_015585057.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_024945846.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_024944867.1 5 MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism" XP_015595308.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024943032.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_024937944.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015598428.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_015592138.1 6 KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-6922 "Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis" XP_024943045.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_024945519.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024940670.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-166208 "HSF1-dependent transactivation";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling" XP_015604820.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_015587701.1 17 MetaCyc: PWY-6620;MetaCyc: PWY-6627;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-7179;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-6644;MetaCyc: PWY-6608;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1 "Guanine and guanosine salvage";"Salinosporamide A biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Purine metabolism";"Pyrimidine metabolism" XP_024937389.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015606853.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_024947243.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015588810.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024938499.1 26 Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-190861 "Kinesins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly" XP_015604517.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024942765.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015585470.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015610522.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_024941221.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024941406.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015604114.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024944996.1 5 Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37 "PRC2 methylates histones and DNA";"DNA methylation";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism" XP_015601554.1 16 Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243 "Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Vif-mediated degradation of APOBEC3G";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery" XP_024944323.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015593732.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_015597552.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952 "Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions" XP_015605004.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_024946014.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-8951664;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation";"rRNA modification in the nucleus and cytosol" XP_024937883.1 3 Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2 "Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway" XP_024940140.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" XP_024939712.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015585824.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024940121.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_024940582.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_015607796.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015607338.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" XP_015596775.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024945909.1 11 Reactome: R-HSA-9013957;Reactome: R-HSA-5213460;Reactome: R-HSA-5218900;Reactome: R-HSA-69416;Reactome: R-HSA-3371378;Reactome: R-HSA-75157;Reactome: R-HSA-5357786;Reactome: R-HSA-2562578;Reactome: R-HSA-140534;Reactome: R-HSA-75158;Reactome: R-HSA-933543 "TLR3-mediated TICAM1-dependent programmed cell death";"RIPK1-mediated regulated necrosis";"CASP8 activity is inhibited";"Dimerization of procaspase-8";"Regulation by c-FLIP";"FasL/ CD95L signaling";"TNFR1-induced proapoptotic signaling";"TRIF-mediated programmed cell death";"Caspase activation via Death Receptors in the presence of ligand";"TRAIL signaling";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10" XP_024943581.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015591616.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_015605824.1 7 Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_015589137.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015588609.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015590191.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024936322.1 19 Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038 "Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Chylomicron clearance";"Retinoid metabolism and transport";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"VLDL assembly";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL remodeling";"LDL clearance" XP_015587046.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024938358.1 4 Reactome: R-HSA-72731;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_015584831.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024936221.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015605228.1 10 KEGG: 04660+2.7.10.2;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04150+2.7.11.1 "T cell receptor signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"TNFR1-induced NFkappaB signaling pathway";"mTOR signaling pathway" XP_015592722.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015606625.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_024939917.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_024943006.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015608390.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_024938229.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952 "Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Ion homeostasis";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling by BRAF and RAF fusions" XP_015603984.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024939327.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015594156.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015602191.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024937723.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_015602587.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024941066.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015597907.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024937346.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015593908.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015609179.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015596209.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_024946415.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_024939396.1 12 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015599663.1 6 Reactome: R-HSA-5609978;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370 "Defective GALT can cause Galactosemia";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism" XP_015609670.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion" XP_015601567.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015589996.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_015599448.1 5 MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368 "Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_024936403.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_015609237.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015604968.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)" XP_015587446.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015591568.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015610324.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024945311.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" XP_024946962.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015610411.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_015590904.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015592425.1 11 KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964 "Arginine biosynthesis";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II" XP_015589671.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015592197.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015600358.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015606749.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024945757.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015594734.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_024947562.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_015610569.1 6 Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606 "Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_015599464.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_015601857.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838 "Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Activation of SMO" XP_024936007.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015600771.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway" XP_024945642.1 6 Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-912446 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination" XP_015587422.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024941353.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015590565.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015599328.1 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" XP_024945176.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_015590554.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024939347.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_015591866.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_015591972.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015608775.1 28 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-3371453;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-3371511 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of HSF1-mediated heat shock response";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"HSF1 activation" XP_015592921.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607 "Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends" XP_015587569.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Photosynthesis";"ATP biosynthesis";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Ion channel transport";"Transferrin endocytosis and recycling" XP_024945425.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015595167.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015587666.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_024936735.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024937104.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015601991.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73930;Reactome: R-HSA-73933 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)" XP_015608400.1 10 KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3 "Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis" XP_015601839.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015585476.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015594331.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_024939592.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_015591724.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015609264.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015604182.1 4 MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II" XP_015586170.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_015601191.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024947756.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024945394.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015600899.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_015605450.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015586896.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_015586523.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015607515.1 8 Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_015597080.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015593135.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_024942166.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015605148.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024945721.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015609848.1 3 MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117 "Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I" XP_015600963.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024947010.1 9 KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation" XP_024945279.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_015598362.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_015591180.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-5660862 "Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_024938296.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_015599958.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_024940993.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_015609295.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_015593192.1 3 Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117 "Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis" XP_024938904.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_024941710.1 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8040;MetaCyc: PWY-8072 "D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"Alanine racemization" XP_015605414.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015586308.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69205 "Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription" XP_015602677.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_015594163.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015593062.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_015591152.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015584969.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_024946278.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015595816.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024941727.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015587164.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015603896.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_015591487.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015585894.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015608543.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497 "Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_024936107.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway" XP_024937191.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_015605093.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_015599762.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_024947167.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_015604286.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_024947860.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_015591974.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024940373.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015605064.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_024936182.1 10 MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7587 "Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)" XP_015604054.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024936092.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015608583.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015584998.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815 "Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D" XP_024942125.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015595677.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_024937291.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500 "D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle" XP_024939340.1 26 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-389960 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC" XP_024947808.1 24 Reactome: R-HSA-8963896;Reactome: R-HSA-8853659;Reactome: R-HSA-9634600;Reactome: R-HSA-163560;Reactome: R-HSA-5610780;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-422356;Reactome: R-HSA-432040;Reactome: R-HSA-5610785;Reactome: R-HSA-4420097;Reactome: R-HSA-111931;Reactome: R-HSA-163358;KEGG: 04150+2.7.11.11;Reactome: R-HSA-392517;Reactome: R-HSA-381676;Reactome: R-HSA-9010642;Reactome: R-HSA-5610787;Reactome: R-HSA-5621575;Reactome: R-HSA-5610783;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-442720 "HDL assembly";"RET signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Triglyceride catabolism";"Degradation of GLI1 by the proteasome";"PKA activation";"DARPP-32 events";"PKA activation in glucagon signalling";"Regulation of insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"GLI3 is processed to GLI3R by the proteasome";"VEGFA-VEGFR2 Pathway";"PKA-mediated phosphorylation of CREB";"PKA-mediated phosphorylation of key metabolic factors";"mTOR signaling pathway";"Rap1 signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ROBO receptors bind AKAP5";"Hedgehog 'off' state";"CD209 (DC-SIGN) signaling";"Degradation of GLI2 by the proteasome";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_015588029.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015602795.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015609331.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015610471.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_015591714.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015584680.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015596356.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015608624.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015599318.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_015604499.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024938219.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-111932 "Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Ion homeostasis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB" XP_015589502.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015593950.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015588695.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015601884.1 7 Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_015590832.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015610513.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_015585407.2 8 KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"Galactose metabolism";"Streptomycin biosynthesis" XP_015599943.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_024947514.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015604255.1 18 KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;MetaCyc: PWY-6638;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7383 "Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_015603395.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-109704 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade" XP_015608047.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015609530.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024943799.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_015596761.1 9 Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "GPVI-mediated activation cascade";"NRAGE signals death through JNK";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_015586196.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-176408 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase" XP_024946872.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024935930.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015592853.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_015592734.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_015604105.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_024946601.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_015608532.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015590029.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_024943986.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024940832.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024945537.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_015605012.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015588675.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-174113 "Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1" XP_015588470.1 3 MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade" XP_024940581.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015601072.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024936709.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015600414.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_024947361.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024940774.1 5 Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)" XP_015592850.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_015589454.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015604187.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism" XP_015599327.1 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" XP_024946068.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015586067.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_024946989.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015599201.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024946724.1 10 MetaCyc: PWY-4661;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_015604055.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_024939338.1 3 Reactome: R-HSA-202433;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Generation of second messenger molecules";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_024936105.1 5 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway" XP_015610375.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_024935604.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024942629.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_015593084.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015600007.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_024935691.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015598559.1 19 MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;MetaCyc: PWY-5538 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate VI" XP_015603917.1 12 Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25 "Transport and synthesis of PAPS";"Monobactam biosynthesis";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Sulfate activation for sulfonation";"Selenate reduction";"Purine metabolism";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism" XP_015591226.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_015598845.1 5 Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3 "Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_015596911.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_015592913.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_015601812.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910 "HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs" XP_024940334.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024940360.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_015597136.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_024944529.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_015588344.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_015594333.2 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_024947560.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015586758.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015588459.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024940433.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015591327.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_015585451.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015587459.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024946894.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_015604272.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024942672.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_024937436.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024944029.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_024944364.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024942271.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015604717.2 6 Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017 "Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_015587412.1 9 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_015595732.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024939877.1 18 Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417 "Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Synthesis of PA";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)" XP_015590811.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024936621.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024945517.1 6 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;Reactome: R-HSA-189085 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate" XP_015599834.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_015585672.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024936183.1 10 MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051 "Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I" XP_024945590.1 3 Reactome: R-HSA-8964058;Reactome: R-HSA-1369062;Reactome: R-HSA-9029569 "HDL remodeling";"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_015593269.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_024945249.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_015597660.1 13 KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_024941005.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024935814.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015605353.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024935792.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024935674.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015586906.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015604480.1 9 Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-2173796;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex" XP_015590227.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_015599931.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_015600644.1 7 KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_024938913.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015601084.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015606969.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_015604289.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015589226.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015594705.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_015601230.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_015608683.1 3 Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801 "Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)" XP_015599226.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015598136.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_015589080.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_024940980.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015585254.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_015586146.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024943692.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015592841.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024943059.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_015608020.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024936423.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_015586580.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024940796.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015601256.1 7 Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-5696394;Reactome: R-HSA-606279;Reactome: R-HSA-5689880 "HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"UCH proteinases";"Telomere Extension By Telomerase";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere";"Ub-specific processing proteases" XP_024939436.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_015596282.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692 "Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity" XP_024938272.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015608384.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015592914.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_024937775.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015592291.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_024944932.1 5 Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148 "Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015594653.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024935499.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024942600.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_024938701.1 5 Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614 "Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage" XP_024947251.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015603469.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_015605848.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015596638.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015597044.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_015600085.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015592936.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_024935833.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_024944341.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024938853.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_024940964.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_015599510.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_015608146.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_015592183.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015602707.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015593450.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism" XP_015594695.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024937918.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis" XP_015608570.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015596956.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_015597877.1 33 Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-69273;Reactome: R-HSA-167161;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-69656;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-69231;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-69202;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167246 "RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin A/B1/B2 associated events during G2/M transition";"HIV Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of the Early Elongation Complex";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Cyclin D associated events in G1";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_024941507.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015607056.1 14 MetaCyc: PWY-7124;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-1042 "Ethylene biosynthesis V (engineered)";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)" XP_015608948.1 42 Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-110330;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-110329 "Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"HDACs deacetylate histones";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Amyloid fiber formation";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine" XP_024940757.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024943118.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015601885.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;MetaCyc: PWY-7511 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination" XP_024943652.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015605113.1 3 KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45 "Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_015592477.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation" XP_024935837.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_024943932.1 7 KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-7255;MetaCyc: PWY-6840;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2 "Glutathione metabolism";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism" XP_024939593.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_015592052.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_015584708.1 11 Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-674695 "Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events" XP_015602981.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_015594522.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_024935838.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_015586698.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_024947769.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_024941968.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_015587667.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_015609961.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024943933.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_015585224.1 4 MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722 "Choline degradation IV";"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)" XP_015585348.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015589675.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_015603187.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015595830.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015596577.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_015591832.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015607402.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_015592666.2 11 Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-1268020;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-611105 "Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"Mitochondrial protein import";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport" XP_015584989.1 13 MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-1722;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3 "Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes" XP_015603648.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015591651.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174178 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015601321.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_024946580.1 10 Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-7344 "Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis" XP_015597947.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015595600.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_015600191.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015586879.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015599465.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015597537.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135 "Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation" XP_015590069.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015598973.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_015594730.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015608780.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015592873.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)" XP_015603420.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_024944051.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Signaling by BRAF and RAF fusions";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_024940953.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330 "Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_024942278.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024946807.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015607145.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024937106.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024941512.1 20 Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5696397 "Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_024938421.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_015588996.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_024936090.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015590768.2 5 MetaCyc: PWY-2161B;KEGG: 00510+2.4.1.142;KEGG: 00790+3.4.19.9;KEGG: 00513+2.4.1.142;Reactome: R-HSA-6798695 "Glutamate removal from folates";"N-Glycan biosynthesis";"Folate biosynthesis";"Various types of N-glycan biosynthesis";"Neutrophil degranulation" XP_024942573.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_024939719.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_015602619.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-113507 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation" XP_024939174.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015601387.1 11 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_024936516.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_015595976.1 6 Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993 "WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors" XP_015585158.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015606558.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015586617.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_024936240.1 8 KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1 "Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_015596816.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015608448.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015595033.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764 "ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling" XP_015607304.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024946612.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_015588637.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_024945525.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067 "Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_015595455.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_015606282.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_015609665.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809 "Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization" XP_015596285.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2" XP_024941937.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024939044.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015600568.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015590777.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015605075.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_015603228.1 4 Reactome: R-HSA-70263;KEGG: 00010+3.1.3.9;KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9 "Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism" XP_024940910.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024939092.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_015602221.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015599098.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_024937228.1 10 KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11 "Galactose metabolism";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism" XP_015596764.1 9 Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "GPVI-mediated activation cascade";"NRAGE signals death through JNK";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"Rho GTPase cycle";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_024937636.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015599431.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_015593607.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_015592875.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)" XP_015591382.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_024936792.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015585550.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015587363.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_015591482.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_024941067.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015591809.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4 "Neutrophil degranulation";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_024943039.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_024937819.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015592725.1 18 Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409 "Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_015590938.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015596101.1 11 MetaCyc: PWY-5381;MetaCyc: PWY-6607;MetaCyc: PWY-7185;MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-7821;MetaCyc: PWY-6608;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5 "Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Purine metabolism";"Inosine 5'-phosphate degradation";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism" XP_015605298.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024942511.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015604276.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015605940.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport" XP_015598215.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015588320.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_015608755.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015598555.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015600216.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024942429.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015591294.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015598287.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_015586723.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015589497.1 34 Reactome: R-HSA-159227;Reactome: R-HSA-9639288;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464 "Transport of the SLBP independent Mature mRNA";"Amino acids regulate mTORC1";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of RNA binding proteins" XP_024947510.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015606465.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015601228.2 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_015589418.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_024939629.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015585592.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_015605397.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015607688.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024935676.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_015604453.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015604633.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024944676.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_024936903.1 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-380994 "Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_015604627.1 4 MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20 "Taurine biosynthesis I";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism" XP_024940499.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024936122.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024944209.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_024945608.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015584971.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_015593493.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024939217.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_024936494.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015601412.1 3 Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-383280 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015610187.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_015609412.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_015592587.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015595363.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015597228.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015606462.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_015588168.1 5 MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)" XP_015599277.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_015608170.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024944239.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015594838.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024947206.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024947025.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024938655.1 13 MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-6859 "Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis" XP_024942808.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690 "Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events" XP_015597913.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015585130.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_015595340.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015610115.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015599040.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024940174.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133 "Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1" XP_024937964.1 15 Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-176034;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6796648 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interactions of Tat with host cellular proteins";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes" XP_024944698.1 4 MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662 "Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_015602378.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_015599089.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_024937730.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024943117.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024936184.1 10 MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8051 "Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis I" XP_015595786.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_015592271.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015607164.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015585840.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015595412.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_024942745.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015600668.1 7 MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445 "Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation" XP_015599133.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024943937.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015588715.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024936079.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_024940035.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_015586477.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_024943151.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_015601860.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024937923.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins" XP_024937233.1 10 KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385 "Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)" XP_015599504.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_024936302.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015593612.1 4 Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling" XP_015589109.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015587578.1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678 "SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" XP_015602424.1 4 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Laminin interactions" XP_024938340.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_015601304.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_015587784.1 5 MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III" XP_015586548.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015601120.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_015602807.1 17 Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473 "Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint" XP_024939000.1 8 Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade" XP_024943896.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_024947353.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015592385.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015591008.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_024943237.1 4 KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" XP_015587327.1 12 MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-5871 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)" XP_015591546.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024940824.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_024947350.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015607694.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024939308.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015600011.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_015594300.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_015597758.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_015597165.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_015593492.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015605066.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_015605302.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024944614.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015599664.1 6 MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-5609978 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia" XP_024940075.1 18 MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-6545 "CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_015606016.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024939405.1 12 Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015598115.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_024937350.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015595083.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015590332.1 15 MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-2221 "Superpathway of glucose and xylose degradation";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_015598213.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015606307.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024936568.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015599417.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_024937614.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015602297.1 12 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-6804756 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Human papillomavirus infection";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation" XP_015610086.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_024940199.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015589302.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015605230.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015600381.1 17 Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-1834949;Reactome: R-HSA-5685942;Reactome: R-HSA-3270619;Reactome: R-HSA-5685939 "DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Cytosolic sensors of pathogen-associated DNA";"HDR through Homologous Recombination (HRR)";"IRF3-mediated induction of type I IFN";"HDR through MMEJ (alt-NHEJ)" XP_024941503.1 9 Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475 "HS-GAG biosynthesis";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_024941620.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_015589767.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-70268 "Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_015603018.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015605881.1 26 Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69205;Reactome: R-HSA-5358565;Reactome: R-HSA-69183;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-4615885;Reactome: R-HSA-5651801;Reactome: R-HSA-1362277;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-6804114;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-8866654;Reactome: R-HSA-69166;Reactome: R-HSA-110312;Reactome: R-HSA-69091 "Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"G1/S-Specific Transcription";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the lagging strand";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"SUMOylation of DNA replication proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Transcription of E2F targets under negative control by DREAM complex";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Translesion synthesis by POLI";"E3 ubiquitin ligases ubiquitinate target proteins";"Removal of the Flap Intermediate";"Translesion synthesis by REV1";"Polymerase switching" XP_024946569.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015601455.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_015588956.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015609558.1 4 KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_015592528.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_015586633.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024945963.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015603813.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015588867.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_024947770.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015608135.1 9 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series" XP_015606299.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015599250.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Circadian Clock";"RMTs methylate histone arginines";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_015603405.1 7 Reactome: R-HSA-416476;Reactome: R-HSA-140837;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015587693.1 4 KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27 "Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism" XP_024942714.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015608220.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9 "Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_024939928.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_015585209.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015590359.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214 "Estrogen-dependent gene expression";"Meiotic synapsis";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins" XP_015609539.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015608344.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024939410.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015592824.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015593395.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024940064.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_015598487.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_024936445.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015600762.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015598767.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676 "Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_015610295.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_024940438.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_024942197.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015604275.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_024945095.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_015602352.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_024944997.1 5 Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-5334118 "SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"DNA methylation" XP_024940469.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015606814.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024941254.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_024941464.1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" XP_015587828.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_015603739.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015606638.1 4 Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196791 "Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Vitamin D (calciferol) metabolism" XP_024945241.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015606283.1 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation" XP_015591033.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_024939140.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015601545.1 179 Reactome: R-HSA-9633012;Reactome: R-HSA-5685942;Reactome: R-HSA-5357905;Reactome: R-HSA-69481;Reactome: R-HSA-5684264;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-175474;Reactome: R-HSA-349425;Reactome: R-HSA-3322077;Reactome: R-HSA-5655862;Reactome: R-HSA-1295596;Reactome: R-HSA-5693565;Reactome: R-HSA-3785653;Reactome: R-HSA-9645460;Reactome: R-HSA-5610780;Reactome: R-HSA-2173791;Reactome: R-HSA-110312;Reactome: R-HSA-6781823;Reactome: R-HSA-450321;Reactome: R-HSA-936964;Reactome: R-HSA-975163;Reactome: R-HSA-8866654;Reactome: R-HSA-205043;Reactome: R-HSA-5675482;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-975144;Reactome: R-HSA-1169091;Reactome: R-HSA-2644606;Reactome: R-HSA-912631;Reactome: R-HSA-5675221;Reactome: R-HSA-3769402;Reactome: R-HSA-5696400;Reactome: R-HSA-9014325;Reactome: R-HSA-901032;Reactome: R-HSA-174048;Reactome: R-HSA-5607764;Reactome: R-HSA-8948747;Reactome: R-HSA-975956;Reactome: R-HSA-180534;Reactome: R-HSA-2672351;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-937041;Reactome: R-HSA-8866652;Reactome: R-HSA-187577;Reactome: R-HSA-917937;Reactome: R-HSA-5689877;Reactome: R-HSA-156827;Reactome: R-HSA-9646399;Reactome: R-HSA-174154;Reactome: R-HSA-2122947;Reactome: R-HSA-8876493;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-162588;Reactome: R-HSA-69541;Reactome: R-HSA-5696397;Reactome: R-HSA-2408557;Reactome: R-HSA-182971;Reactome: R-HSA-1253288;Reactome: R-HSA-5654733;Reactome: R-HSA-110314;Reactome: R-HSA-8875360;Reactome: R-HSA-382556;Reactome: R-HSA-5656169;Reactome: R-HSA-168638;Reactome: R-HSA-977225;Reactome: R-HSA-5668541;Reactome: R-HSA-8849469;Reactome: R-HSA-174084;Reactome: R-HSA-937039;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-983168;Reactome: R-HSA-6804760;Reactome: R-HSA-6783310;Reactome: R-HSA-937072;Reactome: R-HSA-6804757;Reactome: R-HSA-2559582;Reactome: R-HSA-8948751;Reactome: R-HSA-6782135;Reactome: R-HSA-9637628;Reactome: R-HSA-400253;Reactome: R-HSA-5607761;Reactome: R-HSA-5696394;Reactome: R-HSA-5656121;Reactome: R-HSA-5676590;Reactome: R-HSA-5689901;Reactome: R-HSA-9613829;Reactome: R-HSA-5654726;Reactome: R-HSA-532668;Reactome: R-HSA-6791226;Reactome: R-HSA-2871837;Reactome: R-HSA-2559585;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-72689;Reactome: R-HSA-1358803;Reactome: R-HSA-2691232;Reactome: R-HSA-69017;Reactome: R-HSA-6782210;Reactome: R-HSA-9615710;Reactome: R-HSA-174178;Reactome: R-HSA-5693607;Reactome: R-HSA-1236382;Reactome: R-HSA-5658442;Reactome: R-HSA-72706;Reactome: R-HSA-2559580;Reactome: R-HSA-9033241;Reactome: R-HSA-8863795;Reactome: R-HSA-5696395;Reactome: R-HSA-1169408;Reactome: R-HSA-5654732;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-72764;Reactome: R-HSA-168927;Reactome: R-HSA-2173796;Reactome: R-HSA-2122948;Reactome: R-HSA-4641258;Reactome: R-HSA-2979096;Reactome: R-HSA-975957;Reactome: R-HSA-1236974;Reactome: R-HSA-9013507;Reactome: R-HSA-9636383;Reactome: R-HSA-192823;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-1799339;Reactome: R-HSA-5654727;Reactome: R-HSA-3134975;Reactome: R-HSA-174490;Reactome: R-HSA-5689896;Reactome: R-HSA-110320;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-445989;Reactome: R-HSA-6781827;Reactome: R-HSA-69231;Reactome: R-HSA-2894862;Reactome: R-HSA-4641263;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-937042;Reactome: R-HSA-5205685;Reactome: R-HSA-174184;Reactome: R-HSA-8856828;Reactome: R-HSA-168928;Reactome: R-HSA-975110;Reactome: R-HSA-5687128;Reactome: R-HSA-9013973;Reactome: R-HSA-209543;Reactome: R-HSA-8941858;Reactome: R-HSA-2173788;Reactome: R-HSA-209560;Reactome: R-HSA-5362768;Reactome: R-HSA-2173795;Reactome: R-HSA-180585;Reactome: R-HSA-936440;Reactome: R-HSA-179409;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-450302;Reactome: R-HSA-5689603;Reactome: R-HSA-6804756;Reactome: R-HSA-201681;Reactome: R-HSA-156902;Reactome: R-HSA-69601;Reactome: R-HSA-1234176 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"HDR through Homologous Recombination (HRR)";"Regulation of TNFR1 signaling";"G2/M Checkpoints";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Assembly Of The HIV Virion";"Autodegradation of the E3 ubiquitin ligase COP1";"Glycogen synthesis";"Translesion synthesis by POLK";"Spry regulation of FGF signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myoclonic epilepsy of Lafora";"Alpha-protein kinase 1 signaling pathway";"Degradation of GLI1 by the proteasome";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Translesion synthesis by REV1";"Formation of TC-NER Pre-Incision Complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"E3 ubiquitin ligases ubiquitinate target proteins";"NRIF signals cell death from the nucleus";"Regulation of necroptotic cell death";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of signaling by CBL";"Negative regulation of MAPK pathway";"Deactivation of the beta-catenin transactivating complex";"Dual Incision in GG-NER";"TICAM1,TRAF6-dependent induction of TAK1 complex";"ER Quality Control Compartment (ERQC)";"APC/C:Cdc20 mediated degradation of Cyclin B";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN localization";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Vpu mediated degradation of CD4";"Stimuli-sensing channels";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"IKK complex recruitment mediated by RIP1";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"SCF(Skp2)-mediated degradation of p27/p21";"Iron uptake and transport";"Josephin domain DUBs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Aggrephagy";"APC/C:Cdc20 mediated degradation of Securin";"NOTCH1 Intracellular Domain Regulates Transcription";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"Budding and maturation of HIV virion";"Stabilization of p53";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Selenocysteine synthesis";"EGFR downregulation";"Downregulation of ERBB4 signaling";"Negative regulation of FGFR4 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"InlB-mediated entry of Listeria monocytogenes into host cell";"ABC-family proteins mediated transport";"Termination of translesion DNA synthesis";"NOD1/2 Signaling Pathway";"Amyloid fiber formation";"TNFR2 non-canonical NF-kB pathway";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Autodegradation of Cdh1 by Cdh1:APC/C";"IRAK1 recruits IKK complex";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of TP53 Activity through Methylation";"Fanconi Anemia Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of TP53 Degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of PTEN stability and activity";"Dual incision in TC-NER";"Modulation by Mtb of host immune system";"Circadian Clock";"Dectin-1 mediated noncanonical NF-kB signaling";"DNA Damage Recognition in GG-NER";"Translesion synthesis by POLI";"NIK-->noncanonical NF-kB signaling";"Metalloprotease DUBs";"Chaperone Mediated Autophagy";"Negative regulation of FGFR1 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Major pathway of rRNA processing in the nucleolus and cytosol";"FCERI mediated NF-kB activation";"Oncogene Induced Senescence";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Formation of a pool of free 40S subunits";"Downregulation of ERBB2:ERBB3 signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"CDK-mediated phosphorylation and removal of Cdc6";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Late endosomal microautophagy";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Processing of DNA double-strand break ends";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of RAS by GAPs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Oxidative Stress Induced Senescence";"Peroxisomal protein import";"Downregulation of ERBB2 signaling";"Formation of Incision Complex in GG-NER";"ISG15 antiviral mechanism";"Negative regulation of FGFR3 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Eukaryotic Translation Termination";"TICAM1, RIP1-mediated IKK complex recruitment";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of DVL";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ER-Phagosome pathway";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Prevention of phagosomal-lysosomal fusion";"Viral mRNA Translation";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of FGFR2 signaling";"Regulation of innate immune responses to cytosolic DNA";"Membrane binding and targetting of GAG proteins";"Ovarian tumor domain proteases";"Translesion Synthesis by POLH";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FZD by ubiquitination";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"IRAK2 mediated activation of TAK1 complex";"Pink/Parkin Mediated Mitophagy";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Clathrin-mediated endocytosis";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MAPK6/MAPK4 signaling";"TICAM1-dependent activation of IRF3/IRF7";"p75NTR recruits signalling complexes";"Regulation of RUNX3 expression and activity";"Downregulation of TGF-beta receptor signaling";"NF-kB is activated and signals survival";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Vif-mediated degradation of APOBEC3G";"Negative regulators of DDX58/IFIH1 signaling";"APC-Cdc20 mediated degradation of Nek2A";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"activated TAK1 mediates p38 MAPK activation";"UCH proteinases";"Regulation of TP53 Activity through Phosphorylation";"TCF dependent signaling in response to WNT";"Peptide chain elongation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_024944613.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015595990.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_024935678.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_015590232.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015586225.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379 "ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"HCMV Late Events" XP_015605457.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015596011.1 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" XP_015604588.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_015604348.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_015590926.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_024943068.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015600148.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015594507.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024941940.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015585251.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-2029485 "G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis" XP_015609477.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015586714.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024944203.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015597298.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_024945857.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_024945958.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015598670.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015590932.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_024937802.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_015607521.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_015586241.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015598985.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_024936741.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024940065.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_015609712.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_015598913.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_015589360.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024941642.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_024940141.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_015601294.1 12 Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508 "B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription" XP_015599770.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015595927.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_015603153.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015592069.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_015605270.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015595345.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_024938394.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_015597199.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_024937345.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015608725.1 42 Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-110330;Reactome: R-HSA-912446;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-1912408;Reactome: R-HSA-606279;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-110329;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic recombination";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Pre-NOTCH Transcription and Translation";"Deposition of new CENPA-containing nucleosomes at the centromere";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"HCMV Late Events";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"HDACs deacetylate histones";"Meiotic synapsis" XP_015586458.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_015589461.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878 "EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-mediated anterograde transport" XP_015601670.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_024944360.1 24 Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-4086398 "G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Ca2+ pathway" XP_015598510.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_024944186.1 9 KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00130+2.6.1.5;KEGG: 00950+2.6.1.5 "Tyrosine metabolism";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Tyrosine catabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Isoquinoline alkaloid biosynthesis" XP_015594513.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_024939064.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_024943123.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015598137.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_015596826.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015610264.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_015595233.1 4 KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I" XP_015595637.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_015585333.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015601405.1 5 MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006 "Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_015592231.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_015601045.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_015591087.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_015600645.1 7 MetaCyc: PWY-7176;MetaCyc: PWY-7219;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_024936033.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603 "Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"UCH proteinases" XP_024936514.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024941798.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024947798.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015610122.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015593617.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_015590295.1 3 MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987 "Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis" XP_015588942.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305 "Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D" XP_015594081.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_015610126.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015593483.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_024939456.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_015593881.1 5 Reactome: R-HSA-209543;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-9020702 "p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"Interleukin-1 signaling" XP_024947568.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015604522.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024942843.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024943487.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024945833.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_024940487.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_015587542.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_015604052.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015587364.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_015601593.1 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_015593606.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_024935794.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015587780.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024939804.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_024945929.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_015602491.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_024935466.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099 "Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling" XP_024945162.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_015608391.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015596329.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols" XP_015608779.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015587711.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-400206 "Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly";"Circadian Clock";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha" XP_015586611.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_024946571.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024945974.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_015589191.1 24 Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-2730905;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218921;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-354192;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-202424 "VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Role of LAT2/NTAL/LAB on calcium mobilization";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"VEGFR2 mediated cell proliferation";"Human cytomegalovirus infection";"RSK activation";"Integrin signaling";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"Activation of AKT2";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Downstream TCR signaling" XP_015599186.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015608812.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024945966.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015600382.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_015593615.1 4 Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination" XP_015596374.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_015593147.1 18 Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416 "Synthesis of PA";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_015609291.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_015590022.1 7 KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_024942394.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024936592.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024943681.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024940213.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015597939.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015589583.1 5 KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I" XP_015598608.1 24 Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-392851 "G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor" XP_015592795.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_024936731.1 3 KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857 "Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis" XP_015610121.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024938437.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015589690.1 8 KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171 "Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis" XP_024939705.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024940209.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation" XP_024942413.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015590038.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_015589806.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015592280.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024939335.1 7 Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_024945816.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_015600195.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_015599962.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471 "Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response" XP_015607749.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_015586018.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015598243.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024937400.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015593600.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_024940721.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015590952.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015601834.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_015586040.1 7 KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-71336;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Chitin derivatives degradation" XP_015591078.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015601859.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024938061.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015605411.1 30 Reactome: R-HSA-202424;Reactome: R-HSA-917937;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-69231;Reactome: R-HSA-187577;Reactome: R-HSA-2894862;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-2644606;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264 "Downstream TCR signaling";"Iron uptake and transport";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"Cyclin D associated events in G1";"SCF(Skp2)-mediated degradation of p27/p21";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Prolactin receptor signaling";"Neddylation";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation" XP_015595410.1 6 KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_024945099.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024942705.1 12 KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-1187;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-601 "Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan" XP_024939650.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015588194.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_015602643.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024937725.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_024941060.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_024938429.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_015602308.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-8875656 "Downstream signal transduction";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"MET receptor recycling" XP_015605725.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_024946861.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_015605210.1 6 KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch biosynthesis" XP_015604602.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024938064.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015610236.1 6 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_015596444.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015593867.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_015589213.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024947632.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_024941015.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015600324.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_015608737.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024947479.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_015603655.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_024947657.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-139853 "DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels" XP_015587591.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015589112.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015602054.1 2 KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128 "mTOR signaling pathway";"MAPK6/MAPK4 signaling" XP_015598379.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015590088.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_024936536.1 7 Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188 "Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" XP_015607488.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024944918.1 29 KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5693565;Reactome: R-HSA-6803207;Reactome: R-HSA-69541;Reactome: R-HSA-5693579;Reactome: R-HSA-6804760;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-349425;Reactome: R-HSA-6803204;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1 "Thermogenesis";"Regulation of TP53 Degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Stabilization of p53";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Methylation";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)";"Autodegradation of the E3 ubiquitin ligase COP1";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection" XP_015595856.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_015602281.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_015595917.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015590502.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015591420.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015603501.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015606543.1 42 Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-606279;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-912446;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-110330 "Meiotic synapsis";"HDACs deacetylate histones";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Processing of DNA double-strand break ends";"HCMV Late Events";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"Deposition of new CENPA-containing nucleosomes at the centromere";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic recombination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_015602159.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015609410.1 12 MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1 "Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism" XP_015595674.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015606436.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_024945283.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_015607810.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_024944358.1 24 Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-420092 "G alpha (s) signalling events";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors" XP_015587854.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_015587495.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_024943034.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015590710.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015604125.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_015586795.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_024944535.1 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" XP_015592762.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897 "RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes" XP_015589716.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015594087.1 27 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5467337;Reactome: R-HSA-8939902;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4641262;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-3371453;Reactome: R-HSA-5250924;Reactome: R-HSA-198323;Reactome: R-HSA-5358751;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-399956;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5467340 "Human papillomavirus infection";"Degradation of GLI2 by the proteasome";"APC truncation mutants have impaired AXIN binding";"Regulation of RUNX2 expression and activity";"Human immunodeficiency virus 1 infection";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Thermogenesis";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human cytomegalovirus infection";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Regulation of HSF1-mediated heat shock response";"B-WICH complex positively regulates rRNA expression";"AKT phosphorylates targets in the cytosol";"S45 mutants of beta-catenin aren't phosphorylated";"Relaxin signaling pathway";"mTOR signaling pathway";"CRMPs in Sema3A signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"AXIN missense mutants destabilize the destruction complex" XP_024935795.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015584822.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_015585517.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015586413.1 7 Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;MetaCyc: PWY-3385;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-7782 "Synthesis of PE";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Plasmalogen biosynthesis" XP_015594736.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_024939633.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024939586.1 31 MetaCyc: PWY-5973;MetaCyc: PWY-8012;MetaCyc: PWY-5367;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-6799;MetaCyc: PWY-5994;MetaCyc: PWY-8047;MetaCyc: PWY-8049;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5142;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5366;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-7388;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-6113;MetaCyc: PWYG-321;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-6519 "Cis-vaccenate biosynthesis";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Pederin biosynthesis";"Fatty acid biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Superpathway of mycolate biosynthesis";"";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I" XP_015597546.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946 "Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants" XP_015585897.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_024939538.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024942203.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015603001.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_015600155.2 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015598760.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676 "Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_015599346.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024947244.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024947312.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024943865.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015609249.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015598846.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024935651.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_024947677.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_015596969.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_024938385.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_015601766.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_015592574.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015597923.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_015603507.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015603065.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024940180.1 27 Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4641262;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5467337;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-399956;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-5250924;Reactome: R-HSA-3371453;Reactome: R-HSA-5358751;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1 "S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Thermogenesis";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human papillomavirus infection";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"APC truncation mutants have impaired AXIN binding";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"CRMPs in Sema3A signaling";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Human cytomegalovirus infection";"Misspliced GSK3beta mutants stabilize beta-catenin";"B-WICH complex positively regulates rRNA expression";"Regulation of HSF1-mediated heat shock response";"S45 mutants of beta-catenin aren't phosphorylated";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway" XP_024945970.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015604752.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015605047.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015610338.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_015605300.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024947779.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015606298.1 4 KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_015599548.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015600508.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_015599808.1 16 KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00020+6.2.1.4;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-5392 "Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II" XP_015586565.1 5 Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency" XP_024944292.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_015598568.1 19 KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5537;MetaCyc: PWY-5913 "Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)" XP_015588599.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation" XP_015594661.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015602945.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_015590015.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015592156.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015602161.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_024937704.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_015586707.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_015604593.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_015602241.1 18 Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4 "Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism" XP_015589076.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_024940337.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607600.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015589603.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Ion homeostasis";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade" XP_015604324.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015605967.1 24 Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids" XP_015600980.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015588974.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015606240.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_024941896.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024942665.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015599761.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_015603895.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024947311.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015585045.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015589625.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607 "Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends" XP_015602800.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015607247.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024941931.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_024935908.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887 "tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation" XP_024946725.1 10 MetaCyc: PWY-4661;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_015604824.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015595422.2 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024943053.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_024940537.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024941399.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015607446.1 4 Reactome: R-HSA-6807062;MetaCyc: PWY-8026;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72 "Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis" XP_015603905.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015604283.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_024946621.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015587392.1 15 Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944 "Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2" XP_015608827.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism" XP_024938829.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015594021.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024940342.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024941022.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_024945239.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_024943817.1 22 MetaCyc: PWY-7592;MetaCyc: PWY-7053;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7727;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7606;MetaCyc: PWY-7602;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-7049 "Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)" XP_024946890.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_024943535.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024938593.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_015585265.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_015595857.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_015594369.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_015599545.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_015593463.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_024942589.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024944321.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_015591483.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_015596747.1 10 Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695 "Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation" XP_024944201.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024938937.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_015601456.1 22 MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7053;MetaCyc: PWY-7592;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6958;MetaCyc: PWY-8041;MetaCyc: PWY-7726;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7727;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-7728;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-7619;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_015603873.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015587306.1 2 Reactome: R-HSA-201681;Reactome: R-HSA-3772470 "TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists" XP_015601492.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015589972.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_024936384.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024946165.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_015600584.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate" XP_015586773.1 6 Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939;Reactome: R-HSA-69166 "Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate" XP_024941437.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_024943061.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015603726.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015606910.1 7 Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)" XP_015589669.1 26 Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024938501.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_015603869.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_015601203.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024936059.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015600667.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation" XP_015592258.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015600129.1 5 KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841 "Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)" XP_015602766.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015604173.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607527.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015584692.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_015606403.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024946404.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024942719.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_024944112.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015597875.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-6784531 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus" XP_024937980.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024944887.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024937965.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167152 "RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat" XP_015585170.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015599306.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015609294.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_024946273.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024946352.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015589420.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_024942594.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_024938216.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-877300 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Interferon gamma signaling" XP_015590406.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024943916.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024940378.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_015585117.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015608650.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015601267.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015591768.1 42 Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-69473;Reactome: R-HSA-5625886 "RNA Polymerase I Promoter Escape";"HCMV Late Events";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Amyloid fiber formation";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Meiotic synapsis";"HDACs deacetylate histones";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_015600268.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" XP_015589042.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_024941526.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015590673.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015592900.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_024942338.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_015586157.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015600896.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_015602983.1 8 Reactome: R-HSA-5659996;Reactome: R-HSA-71336;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6;KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-6791461;MetaCyc: PWY-5723 "RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt" XP_015594001.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015584917.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_015609680.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509 "Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling" XP_024938998.1 8 Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade" XP_015587373.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024945719.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015604036.1 4 KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50 "Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines";"Arginine and proline metabolism" XP_015603498.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015589049.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015587434.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_024937917.1 3 Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638 "Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_015606802.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-7199;MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5 "Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism" XP_024935689.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_024937325.1 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)" XP_015593631.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015584990.1 13 MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-5030;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3 "Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes" XP_024939047.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024945954.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024943192.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_015598449.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015590548.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015600114.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_015606309.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024946821.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_024945492.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024940340.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015605065.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_015607346.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_015589672.1 26 Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025 "Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation" XP_015609118.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_024936916.1 6 Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731 "FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3" XP_015592859.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024941527.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015593959.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-156711 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events" XP_024941957.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_015608983.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015589106.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015608654.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_015610193.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024943812.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024945874.1 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_015586776.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015597109.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_024945968.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015591079.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015607310.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015592133.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015596286.1 16 Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897 "Ca2+ pathway";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes" XP_015610093.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_024936739.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015588976.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015610265.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_024943565.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_015609743.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_024941014.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015597214.1 4 MetaCyc: PWY-8040;MetaCyc: PWY-7383;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1 "Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"D-Alanine metabolism" XP_015598278.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation" XP_015598253.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024947256.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015596007.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015604497.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741 "Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_015604735.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024942999.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_015591540.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-532668 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_015589452.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_024938333.1 6 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171 "Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions" XP_015592157.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015587458.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024940692.1 56 Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-187577 "Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21" XP_024945872.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_015605932.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_015610087.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015602353.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015607216.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_015590617.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_015599634.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015588979.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_015585083.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_015586741.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_024936725.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_015602288.1 20 MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-6837 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" XP_015597789.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_015598209.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015591821.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_015604370.1 13 MetaCyc: PWY-6842;Reactome: R-HSA-196836;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7533;KEGG: 00053+1.8.5.1 "Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Gliotoxin biosynthesis";"Ascorbate and aldarate metabolism" XP_015591548.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015588273.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024944896.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes" XP_024936511.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024942241.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_015602247.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015588657.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_024944350.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024946642.1 8 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_015588272.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024945439.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024943574.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_024937679.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288 "Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1" XP_015609856.1 13 Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7227 "Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_015607935.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015594697.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015607470.1 10 Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6554 "Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)" XP_015597406.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015605852.1 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_015597966.1 23 Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-4086398;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-456926 "Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (s) signalling events";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"Ca2+ pathway";"Glucagon-type ligand receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)" XP_015591105.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015593786.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024939745.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015592940.1 7 MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-7625 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)" XP_024947396.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015600761.1 14 MetaCyc: PWY-6999;MetaCyc: PWY-6608;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6596;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00232+1.17.3.2;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6538 "Theophylline degradation";"Guanosine nucleotides degradation III";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Purine catabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Caffeine metabolism";"Purine metabolism";"Inosine 5'-phosphate degradation";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)" XP_015597244.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289 "Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation" XP_015594731.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015588791.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_015599392.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_024946006.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015595165.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015587251.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015585298.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024947829.1 4 Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_024944196.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_015587399.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015592421.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_015602390.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_015586242.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015593166.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024945399.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015608938.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024946044.1 14 Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_015594043.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" XP_024935841.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening" XP_024945942.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015596120.1 5 Reactome: R-HSA-4755579;Reactome: R-HSA-193048;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199 "Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_015594144.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_024946609.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_015593689.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_015585066.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_024937098.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism" XP_015591664.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_015585862.1 3 MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation" XP_015590273.1 12 MetaCyc: PWY-7118;KEGG: 00620+2.3.3.9;KEGG: 00660+4.1.3.25;MetaCyc: PWY-7294;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5744;MetaCyc: PWY-7854;KEGG: 00720+4.1.3.25;MetaCyc: PWY-5749;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7295 "Chitin degradation to ethanol";"Pyruvate metabolism";"C5-Branched dibasic acid metabolism";"D-xylose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Glyoxylate assimilation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"Glyoxylate and dicarboxylate metabolism";"L-arabinose degradation IV" XP_015600999.1 2 Reactome: R-HSA-804914;Reactome: R-HSA-9029569 "Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_015595336.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_015586237.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_015595697.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_024943719.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_015585593.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_015597917.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_015609260.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024937748.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_015598665.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015596396.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024943703.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_024941305.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015586411.1 10 MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00710+2.7.2.3;MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-7003;Reactome: R-HSA-70263 "Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Gluconeogenesis" XP_024938488.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_015592619.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_015597679.2 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_015587319.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015591738.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015589866.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015600618.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_024939870.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_015595744.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015585258.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876 "Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs" XP_015587959.1 5 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_015593852.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation" XP_024939325.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_024939403.1 12 Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-166208 "Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling" XP_015602551.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_024939879.1 26 Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-5621575;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508 "Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"Circadian Clock";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription" XP_024941074.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015599708.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_015598781.1 13 Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-9645460 "CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway" XP_024943562.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_024938788.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_015590329.2 15 MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-7383 "Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_024944985.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_024946820.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_015605354.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024941624.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_015588839.1 17 MetaCyc: PWY-6722;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-3371599 "Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Jadomycin biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency" XP_015602646.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015592235.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024944291.1 17 Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_015601452.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015592740.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015607495.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes" XP_024943561.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471 "Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response" XP_024937107.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024935791.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015585646.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_015604398.1 13 Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"mTOR signalling";"PIP3 activates AKT signaling";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes" XP_015585723.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379 "Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events" XP_024941662.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015603284.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015597911.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015585870.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_024943329.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658 "COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_015584718.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_015602801.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_024946806.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015604518.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015609970.1 14 Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5696397 "PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_015607696.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024935921.1 4 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_015602090.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024944337.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024940862.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015604885.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024943015.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_024936234.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024935687.1 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_015592787.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024937976.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015598339.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015586145.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015609185.1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling" XP_024945019.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015606841.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_015586701.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_015589315.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015590063.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_015597493.1 10 KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-2201 "Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate transformations I" XP_015608424.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015610584.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015606449.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport" XP_015597497.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_015602666.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015601877.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015606840.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_024945431.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_015600063.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_015601969.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015586815.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024945058.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015608865.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_015595228.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015592823.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024937974.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024945011.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015585255.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_015590281.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015610380.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_015599076.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015591171.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_024938134.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015610582.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_015608939.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015602951.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024939741.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015601438.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015585205.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024947764.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015600927.1 5 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-201722 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex" XP_024944987.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_015589113.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024940157.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015595607.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015588548.1 1 Reactome: R-HSA-419771 "Opsins" XP_024943741.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015606995.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_024947518.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_015607983.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015585732.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015589065.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024936086.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015585162.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes" XP_024944663.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024940271.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015606045.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015605410.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_024944230.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_024941923.1 3 Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639 "Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis" XP_015592178.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-202433;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules";"RHO GTPases Activate WASPs and WAVEs" XP_015598606.1 6 KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-7442 "Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis" XP_015586222.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015595501.1 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" XP_024941932.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_015599397.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_024942931.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_024945538.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_015585683.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015602452.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015591429.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015598451.1 9 Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-9617324 "Synaptic adhesion-like molecules";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_015605121.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015605174.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015603862.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" XP_024942735.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_024940507.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_015584701.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015597510.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015609645.1 8 Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695 "SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation" XP_015606912.1 7 Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607 "SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends" XP_015585210.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015610293.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024947453.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024946137.1 13 MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism" XP_015600993.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_015604847.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_024947260.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024940359.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_015595966.2 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_015606813.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015588985.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_024936492.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015598434.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015599179.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024941323.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015595928.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024945105.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015592887.1 5 Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006 "Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_015592125.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024941402.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015607570.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024945054.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_015592842.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024938217.1 19 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001 "Ion homeostasis";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade" XP_024943680.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015586315.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery" XP_015585952.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015602103.1 42 Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-110328 "HDACs deacetylate histones";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_015591436.1 8 Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_024942718.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_015605751.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_024936504.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015608449.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024944999.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015589808.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024942377.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_015601582.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015605322.1 29 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167152 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat" XP_024941320.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015608889.2 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_015595224.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015598391.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_015603045.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015592855.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_015594784.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024946721.1 10 MetaCyc: PWY-6362;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6554 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)" XP_015592732.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015600634.1 12 MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5857;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-5870;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856 "Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)" XP_015605377.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024938062.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015591272.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015585081.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_015597843.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015585377.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015592615.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_015601668.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_024937046.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024941622.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_015607792.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024940593.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379 "ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"snRNP Assembly";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"HCMV Late Events" XP_024935497.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015597350.1 11 Reactome: R-HSA-446205;MetaCyc: PWY-3881;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-882;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8 "Synthesis of GDP-mannose";"Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism" XP_024935950.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015587675.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024937271.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs" XP_024935948.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015598148.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_015587015.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015602286.1 6 MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-622;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis";"Glycogen synthesis" XP_015609197.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024947139.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_015588070.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_024939874.1 18 MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925 "Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Synthesis of PA";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Ether lipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG" XP_015584974.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_024940772.1 5 MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis" XP_015607262.1 52 Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-76066;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-73780;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-1834949;Reactome: R-HSA-8851708;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-76061;Reactome: R-HSA-6803529;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-73980 "NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Cytosolic sensors of pathogen-associated DNA";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"FGFR2 alternative splicing";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Termination" XP_024940965.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_024943773.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024940494.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015594569.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_024938060.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015598234.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858 "snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines" XP_024946845.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015589546.1 13 MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-5537 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V" XP_015602442.1 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015590879.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_015599904.1 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" XP_015607340.1 11 MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-7124;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42 "TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)" XP_024938145.1 7 Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11 "Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system" XP_015600263.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_024942035.1 19 MetaCyc: PWY-5392;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5172;Reactome: R-HSA-71403;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5 "Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes" XP_015598563.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015587302.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024947793.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015589467.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy" XP_015602989.1 6 MetaCyc: PWY-7356;MetaCyc: PWY-6907;MetaCyc: PWY-6898;MetaCyc: PWY-6908;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2 "Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism" XP_024947072.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9 "Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_015598200.2 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015599529.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_015587451.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015596330.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis" XP_015604118.1 15 Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938 "HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)" XP_024943046.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015597195.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024937230.1 10 MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11 "1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway" XP_015594691.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024938658.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015588838.1 17 Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;MetaCyc: PWY-4381;MetaCyc: PWY-5743;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679 "Biotin transport and metabolism";"Fatty acid biosynthesis";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Carnitine metabolism";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis" XP_015605008.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015597625.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015589222.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015589993.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_015589899.1 2 KEGG: 00311+1.21.3.1;MetaCyc: PWY-5629 "Penicillin and cephalosporin biosynthesis";"Isopenicillin N biosynthesis" XP_015586502.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015593616.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_015595260.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_015599938.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_015585734.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015586255.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015606113.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_015603316.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024943907.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_015603358.1 1 Reactome: R-HSA-73614 "Pyrimidine salvage" XP_024937825.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015605815.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_024945164.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024942029.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation" XP_015607690.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024944912.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_024944102.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015607107.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015604739.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015606607.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015599135.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015597555.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants" XP_015599539.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015597173.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015592703.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" YP_002889395.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015601103.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015605154.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_024941404.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015593734.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880 "UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases" XP_024941689.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024942925.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015602467.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024938178.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_015607201.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_015587857.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015597139.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015585506.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015586777.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_024940922.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024937399.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015602096.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024935770.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015593171.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015606221.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024936124.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_024941750.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015610144.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670 "Sialic acid metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis" XP_015595730.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015610218.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_015587766.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_015598752.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676 "Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_024935549.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015603037.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024935969.1 5 Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16 "Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation" XP_015585403.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_015586148.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_015585453.1 42 Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-110328;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-606279;Reactome: R-HSA-3214841;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-110329;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632 "Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"Deposition of new CENPA-containing nucleosomes at the centromere";"PKMTs methylate histone lysines";"Packaging Of Telomere Ends";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Cleavage of the damaged pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"HDACs deacetylate histones";"Meiotic synapsis" XP_015585654.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_015606793.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)" XP_024943049.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_024936513.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024941228.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015595321.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024936618.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015599343.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015609521.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_024941295.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_015586903.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015599246.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_024947772.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015586478.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_024938220.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-442982 "Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ion homeostasis";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_024941748.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015609194.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015593957.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69205 "Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription" XP_015588607.1 9 Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897 "mTOR signalling";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes" XP_024940468.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_024935793.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024943846.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015599069.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024947767.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_024938334.1 6 Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_015590610.1 7 MetaCyc: PWY-7158;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1 "L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_015609792.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015609971.1 14 Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400 "Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER" XP_015604647.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015598235.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858 "snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines" XP_024938756.1 3 KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_024936910.1 11 Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" XP_015594052.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_024944472.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_024945752.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_015591475.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_015603277.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015608542.1 24 Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276 "COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Gap junction assembly";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_015604641.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015607678.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024938800.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024937574.1 5 MetaCyc: PWY-6012-1;Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012;MetaCyc: PWY-6289 "Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism";"Petrobactin biosynthesis" XP_015608168.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015604358.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_024935596.1 13 Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928663 "G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"PI3K-Akt signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse" XP_015605711.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015605536.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024944616.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024938339.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_024946163.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015591242.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015607050.1 12 KEGG: 00630+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-6672;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7857 "Glyoxylate and dicarboxylate metabolism";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"Propanoate metabolism";"Methane metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Adlupulone and adhumulone biosynthesis" XP_015602171.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_015585201.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024937700.1 14 MetaCyc: PWY-181;MetaCyc: PWY-2201;MetaCyc: PWY-1622;Reactome: R-HSA-196757;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1 "Photorespiration ";"Folate transformations I";"Formaldehyde assimilation I (serine pathway)";"Metabolism of folate and pterines";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Methane metabolism" XP_015598732.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015590813.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015594404.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_015606099.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_015598147.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_024944882.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015596877.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015589279.1 17 Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8951664;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178 "Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Neddylation";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015586804.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024944608.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015589501.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_024942603.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015602434.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015595121.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015606308.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_024945503.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015596985.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation" XP_024946119.1 5 Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2 "Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" XP_024940270.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_024944615.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015607525.1 8 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_024936791.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024941497.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015585835.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015589451.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015597395.1 10 KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23 "Glycosaminoglycan degradation";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" XP_015588298.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041 "Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" XP_015591795.1 5 Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism" XP_015593643.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_015592366.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024937110.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_024943199.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_024944904.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015598774.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024941166.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_024935685.1 6 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" XP_015590432.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN" XP_015588537.1 9 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway" XP_015599463.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015587403.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_024940341.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015599944.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015588011.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015600760.1 14 KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6538;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;KEGG: 00232+1.17.3.2;MetaCyc: PWY-5497;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6607;Reactome: R-HSA-8851680;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-6999 "Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine metabolism";"Inosine 5'-phosphate degradation";"Caffeine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine catabolism";"Guanosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Theophylline degradation" XP_015594407.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015600157.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015586068.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_015589798.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015601178.1 3 Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144 "Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_015597012.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015593826.1 14 Reactome: R-HSA-611105;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7279;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403 "Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)" XP_024940206.1 5 Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;MetaCyc: PWY-922 "Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I" XP_024943358.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_024943239.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" YP_002889391.1 7 MetaCyc: PWY-3781;Reactome: R-HSA-611105;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;MetaCyc: PWY-4302 "Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"Fe(II) oxidation";"Complex I biogenesis";"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)" XP_015603952.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_024936142.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins" XP_024947795.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015604773.1 60 KEGG: 00720+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00930+4.2.1.17+1.1.1.35;Reactome: R-HSA-77348;MetaCyc: PWY-7007;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;Reactome: R-HSA-1482798;KEGG: 00640+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00650+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;Reactome: R-HSA-77310;MetaCyc: PWY-5138;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-6946;MetaCyc: PWY-7401;Reactome: R-HSA-77285;KEGG: 00310+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-6944;MetaCyc: PWY-5789;MetaCyc: PWY-7216;MetaCyc: PWY-7606;Reactome: R-HSA-77350;MetaCyc: PWY-5136;MetaCyc: PWY-5177;KEGG: 00280+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-1361;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-6945;MetaCyc: PWY-7654;MetaCyc: PWY-7094;Reactome: R-HSA-77288;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346 "Carbon fixation pathways in prokaryotes";"Geraniol degradation";"Fatty acid degradation";"Caprolactam degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Methyl ketone biosynthesis (engineered)";"Caprolactam degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Tryptophan metabolism";"2-methylpropene degradation";"Acyl chain remodeling of CL";"Propanoate metabolism";"Lysine degradation";"Pyruvate fermentation to butanol I";"Butanoate metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"Aminobenzoate degradation";"Benzoate degradation";"Benzoate degradation";"beta-Alanine metabolism";"Butanoate metabolism";"Fatty acid degradation";"Tryptophan metabolism";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Lysine degradation";"Limonene and pinene degradation";"Pyruvate fermentation to butanol II (engineered)";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Methyl tert-butyl ether degradation";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fatty acid beta-oxidation II (plant peroxisome)";"Glutaryl-coa degradation";"Valine, leucine and isoleucine degradation";"Valine, leucine and isoleucine degradation";"Toluene degradation";"Spodoptera littoralis pheromone biosynthesis";"Benzoyl-coa degradation I (aerobic)";"Phenylalanine metabolism";"Fermentation to 2-methylbutanoate";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid salvage";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid elongation";"Fatty acid degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA" XP_024947704.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines" XP_015588837.1 17 Reactome: R-HSA-2426168;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-3371599 "Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Propanoate metabolism";"Jadomycin biosynthesis";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency" XP_024946167.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_024943162.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_015584887.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins" XP_024946585.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_015593799.1 5 Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233 "TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway" XP_015588972.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015594958.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015591172.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015601034.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024946275.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015602558.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_015603123.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024941592.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015610417.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_024936275.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024936250.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes" XP_015607524.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015594433.1 2 MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_015595153.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024941734.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024945512.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_024946371.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_024937937.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024943314.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_015603209.1 10 Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692 "Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity" XP_015609281.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_024945932.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015602381.1 13 Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2022090;Reactome: R-HSA-419037;Reactome: R-HSA-1650814;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157 "Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Collagen degradation";"Collagen chain trimerization";"Integrin cell surface interactions";"ECM proteoglycans";"Assembly of collagen fibrils and other multimeric structures";"NCAM1 interactions";"Collagen biosynthesis and modifying enzymes";"Extracellular matrix organization";"Laminin interactions" XP_015591737.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015587193.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015597248.1 12 KEGG: 04150+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648 "mTOR signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK" XP_024939595.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_024942450.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015595666.1 3 KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis" XP_015586608.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015598354.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015598673.1 6 MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442 "Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis" XP_015607461.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024945018.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015595665.1 8 Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-113501 "Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"DNA replication initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" XP_024942371.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_024938852.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015602215.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_024939591.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_015589766.1 7 Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1 "Signaling by Retinoic Acid";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_024944412.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015593942.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015596453.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015608103.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015606836.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015585915.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_024937806.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_015609378.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_024940849.1 18 KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803 "Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing" XP_015609906.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_015592583.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015606470.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015589897.1 4 Reactome: R-HSA-446193;KEGG: 00311+1.21.3.1;Reactome: R-HSA-5633231;MetaCyc: PWY-5629 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Penicillin and cephalosporin biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Isopenicillin N biosynthesis" XP_015596892.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)" XP_015605238.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation" XP_015606102.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_024942329.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024944777.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015610378.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening" XP_015604914.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_015596903.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015599221.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_024942362.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_015585918.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_024936972.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024938350.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015600042.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_024947566.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_015590573.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015608207.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_015587965.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015607661.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_015604740.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015587623.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015605463.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015607681.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015588280.1 5 MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)" XP_015599665.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_015602799.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024946746.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_024946284.1 4 Reactome: R-HSA-196791;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Vitamin D (calciferol) metabolism";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015598443.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_024938209.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-877300 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion homeostasis";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling" XP_024944206.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015592800.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_024936382.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015586660.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015597924.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_015608527.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015603396.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling" XP_015593677.1 10 MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-7571;KEGG: 00650+2.3.3.10;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781 "Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Ferrichrome A biosynthesis";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression" XP_024943693.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_015595930.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_015607811.1 17 Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-139915;Reactome: R-HSA-69202;Reactome: R-HSA-111448;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-113501;Reactome: R-HSA-8953750;Reactome: R-HSA-69231;Reactome: R-HSA-1538133 "Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"Activation of PUMA and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Activation of NOXA and translocation to mitochondria";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional Regulation by E2F6";"Cyclin D associated events in G1";"G0 and Early G1" XP_024946173.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER" XP_015607861.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation" XP_015592904.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015589074.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_015600954.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_015599914.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024947231.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_015605296.1 42 Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-1912408;Reactome: R-HSA-606279;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-110330;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-2559580 "Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"HCMV Late Events";"Amyloid fiber formation";"Packaging Of Telomere Ends";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Pre-NOTCH Transcription and Translation";"Deposition of new CENPA-containing nucleosomes at the centromere";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones";"Meiotic synapsis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"Oxidative Stress Induced Senescence" XP_024946070.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015598663.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015589795.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_015597719.1 4 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_024939052.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015607000.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_015586904.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_024946737.1 4 KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026 "Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)" XP_015604950.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8055 "Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis" XP_024936346.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024940878.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015600383.1 17 Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-3270619;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-1834949;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"IRF3-mediated induction of type I IFN";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)" XP_015594789.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024937829.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015587517.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_024935681.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_015588269.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_024938966.1 11 Reactome: R-HSA-168138;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-109704;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137 "Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"PI3K Cascade";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" XP_024946644.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024936662.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_015603646.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015598084.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024937777.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015600828.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015601968.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024937942.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015610262.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_015588788.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_024941396.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1 "G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state";"Purine metabolism" XP_024944645.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-2219530 "PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_024946414.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015605155.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_015587455.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015594161.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024942706.1 12 KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-1187;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-601 "Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan" XP_015586589.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015595913.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015604814.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015595965.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_024936348.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024941132.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_015610171.1 7 MetaCyc: PWY-7185;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-6545 "UTP and CTP dephosphorylation I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_015607626.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015594299.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_015607852.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015600228.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_024939746.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024943374.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015602955.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015597096.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_015589803.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024944194.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015591324.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_015590139.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015598953.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897 "mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes" XP_015586282.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555 "Purine metabolism";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events" XP_024944898.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024943545.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015590847.1 6 KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes" XP_015609960.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024944246.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024943953.1 6 Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110373 "Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_024940536.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024942809.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_024938255.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_015593618.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015598759.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844 "Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_015593722.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_015584682.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_024937213.1 14 Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-6453 "Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Synthesis of PC";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Stigma estolide biosynthesis" XP_015604034.1 4 KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines" XP_024944992.1 15 Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693571 "Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)" XP_015588106.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024940822.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015587406.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_015587552.1 7 Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2 "Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism" XP_015585739.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024942363.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_015599538.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015590995.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015590255.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015596302.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_015605089.1 11 MetaCyc: PWY-7790;MetaCyc: PWY-5154;Reactome: R-HSA-500753;KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7400;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7791 "UMP biosynthesis II";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis III" XP_015599113.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_024940601.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024945931.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_024947208.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_024947579.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015594457.1 4 MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49 "Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway" XP_015593810.1 5 Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_015606427.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_015595633.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_015605276.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015595327.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-418594 "Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events" XP_024943352.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_015601716.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015597542.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_024942924.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015602089.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024945400.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_015609408.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_024945964.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015594053.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" XP_015600031.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024936875.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_015605086.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_015589689.1 8 KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism" XP_015608726.1 42 Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-2559580;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582 "PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Amyloid fiber formation";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Escape";"HCMV Late Events";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"HDACs deacetylate histones";"Oxidative Stress Induced Senescence";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)" XP_015606285.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_024944188.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024947561.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_015588085.2 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_024937681.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through Homologous Recombination (HRR)" XP_024943418.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_024938803.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015594660.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024937697.1 7 MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-882 "GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_024941499.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024935677.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_015606250.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024944459.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015608864.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_015585680.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015588973.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015601199.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015594325.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015584709.1 11 Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery" XP_015597906.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024945154.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015593601.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_015598513.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_015586182.1 11 Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway" XP_024942235.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024937729.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015602005.1 10 Reactome: R-HSA-5689880;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1 "Ub-specific processing proteases";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"HATs acetylate histones";"Human immunodeficiency virus 1 infection" XP_015587682.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis" XP_015601085.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024941525.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015609254.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_015586440.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" XP_015597081.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024941405.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015607677.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015598299.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_015599520.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_015597909.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015609543.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024937360.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015604531.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024937957.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015589314.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015592601.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015607496.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015586475.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_015604742.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024943109.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015591075.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015606554.1 5 MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-6906 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)";"Chitin derivatives degradation" XP_024945856.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_015587285.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015585643.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_015605381.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_024942341.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_024938700.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024936868.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024936000.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015590028.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015596813.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684 "SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"UCH proteinases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state" XP_024940785.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159 "TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling" XP_015609247.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_024936512.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015587961.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_015602426.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015599166.1 12 Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-601 "Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan" XP_015602948.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015604347.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_015591831.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024940778.1 8 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling by Hippo";"Relaxin signaling pathway" XP_015606428.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_015605876.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_015610298.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_015595001.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024946701.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_024943177.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_015587764.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015599506.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_015601337.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024941183.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_015592489.1 13 Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-437239 "LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Recycling pathway of L1" XP_015585650.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_015595612.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_015597133.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015590305.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_024945754.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_024936404.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_024937410.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024942170.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015589169.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015606555.1 5 Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6906 "Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation" XP_015585688.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015608580.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015585917.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_024938030.1 4 Reactome: R-HSA-1234176;Reactome: R-HSA-3232142;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SUMOylation of ubiquitinylation proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_024936006.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015584852.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607284.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024947165.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015605019.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_015588944.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857 "Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation" XP_015589551.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024945722.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024936356.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_015587188.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015603961.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024937956.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015598270.1 14 MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-6969 "Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_024946967.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024936451.1 3 MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217 "Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage" XP_024939173.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015587370.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024940927.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_015590235.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024938419.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_015606700.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_024944254.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_015607411.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_015584898.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_024939341.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024939597.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_024942949.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015599578.1 5 MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis" XP_015595485.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_015595776.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_024943010.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015608021.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015603164.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015593772.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024941668.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015599455.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_015596668.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-430039 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_024945973.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_015589793.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015609101.2 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)" XP_024945055.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024941667.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015593326.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024938656.1 13 MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-6859 "Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis" XP_015586609.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_024941105.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015586709.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015601624.1 52 Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-749476;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-5578749 "RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Abortive And Retractive Initiation";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs" XP_015588766.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_015606466.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015596886.1 8 Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873 "Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation" XP_015588202.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_015599134.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015600948.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_015609265.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024937056.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024940672.1 5 Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-165159 "AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling" XP_015601065.1 4 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_015599956.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_024941481.1 5 KEGG: 00100+1.3.1.72;Reactome: R-HSA-2022377;Reactome: R-HSA-6807047;MetaCyc: PWY-8026;Reactome: R-HSA-6807062 "Steroid biosynthesis";"Metabolism of Angiotensinogen to Angiotensins";"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol" XP_015595671.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015588601.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy" XP_024936256.1 7 Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606 "Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015590642.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015596527.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015592490.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_024938959.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174178 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_024944782.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015591554.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015586901.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015604871.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015600141.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015609801.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_015605418.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015595360.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015606835.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015608482.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_015591425.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024935961.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024936038.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015605746.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_015605074.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_024936385.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024938671.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015599145.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_015601458.1 22 MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7727;MetaCyc: PWY-7725;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7053;MetaCyc: PWY-7592;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6958 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis I (lower eukaryotes)" XP_015608251.1 4 Reactome: R-HSA-8964539;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Glutamate and glutamine metabolism";"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015599225.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015589108.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015598574.1 6 KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Galactose metabolism" XP_024937608.1 4 MetaCyc: PWY-2781;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75 "Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Zeatin biosynthesis" XP_024940414.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015593804.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_015589579.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015593801.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane" XP_024944595.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_024936334.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015607629.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972 "Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_015591176.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_015603703.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015607303.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015587598.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_015603731.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015606867.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015605817.1 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_015596561.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_015591961.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024939213.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-9609523 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015591426.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015598658.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015609747.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_015597985.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629 "ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_024942189.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_024943051.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_024940357.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_015600222.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024941583.1 2 Reactome: R-HSA-8934593;Reactome: R-HSA-69231 "Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1" XP_015599940.1 16 Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-166058;Reactome: R-HSA-5602498;Reactome: R-HSA-975871;Reactome: R-HSA-975155;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-1257604;Reactome: R-HSA-9020702;Reactome: R-HSA-1810476;Reactome: R-HSA-5602680;Reactome: R-HSA-975138 "TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"PIP3 activates AKT signaling";"Interleukin-1 signaling";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" XP_015588945.1 5 Reactome: R-HSA-2022857;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14 "Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation" XP_015594767.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024940159.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015593213.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015598477.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024935962.1 6 Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_015596540.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_024946402.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015605832.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_024944866.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527 "Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation" XP_024947564.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_015591966.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015597753.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015609513.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024940037.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy" XP_015592259.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_015603476.1 4 KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism" XP_015585378.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015595309.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024943720.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_015598256.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024936912.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782 "Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis" XP_024941973.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_015604910.1 11 Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_024944085.1 17 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9022692;Reactome: R-HSA-68877;Reactome: R-HSA-174178;Reactome: R-HSA-141444;Reactome: R-HSA-4615885 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"EML4 and NUDC in mitotic spindle formation";"Relaxin signaling pathway";"Regulation of MECP2 expression and activity";"Mitotic Prometaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins" XP_024943147.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_015586138.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015607065.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015596380.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_015586728.1 5 KEGG: 00240+2.7.1.21;Reactome: R-HSA-73614;Reactome: R-HSA-69205;KEGG: 00983+2.7.1.21;MetaCyc: PWY-7199 "Pyrimidine metabolism";"Pyrimidine salvage";"G1/S-Specific Transcription";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage" XP_024938995.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_015596353.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015597202.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015602169.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_015608808.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015597964.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015593972.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024939449.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015605909.2 7 Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015603339.1 1 MetaCyc: PWY-6938 "NADH repair" XP_015584707.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015600406.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015597483.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_024939397.1 12 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015602413.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_024942385.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015593771.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015600006.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_015592736.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_015587725.1 5 MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-7863 "5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis" XP_015607200.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_024941898.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015597912.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015595583.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_015610512.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_015609018.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_024940996.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_015609542.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015599528.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015597181.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024940848.1 18 KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803 "Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing" XP_015600480.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015592095.1 42 Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-2559580 "Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"Processing of DNA double-strand break ends";"HCMV Late Events";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDACs deacetylate histones";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"Oxidative Stress Induced Senescence" XP_024942115.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015592802.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_024944872.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015593857.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015604753.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_015595702.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015604349.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015589326.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015587568.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_015603026.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_015597637.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_015605561.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015590439.1 6 MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484 "Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_024942331.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015609838.1 1 Reactome: R-HSA-419771 "Opsins" XP_015594365.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_015595761.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167246 "Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_024939446.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015605722.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015592097.1 25 Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483 "EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs" XP_024936405.1 22 MetaCyc: PWY-7592;MetaCyc: PWY-7053;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6958;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7727;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7726;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-5353;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7728;MetaCyc: PWY-7049 "Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)" XP_015609411.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_024941498.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015597785.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_024941641.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_015601674.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_024942411.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024942849.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024939306.1 26 Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion" XP_015605607.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_015599579.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_015584903.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015589986.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6811440 "Clathrin-mediated endocytosis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network" XP_015596713.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024945158.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024947405.1 42 Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-110330;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-427389;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-2559580;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-5250924 "HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected purine";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"HCMV Late Events";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"Oxidative Stress Induced Senescence";"HDACs deacetylate histones";"Meiotic synapsis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression" XP_015598802.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015610278.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015606972.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-75953 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation" XP_015597702.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024937415.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015596669.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-430039 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_024946768.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024947538.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_015586666.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015586768.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion" XP_015606855.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_015594655.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015595693.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_024936840.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_024941745.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_024941749.1 6 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_015607423.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015584965.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_015594464.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015589317.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015594991.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015589183.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_024946178.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_015607178.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015596808.1 4 KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" XP_024944453.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015590330.1 15 Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-2221 "Glycolysis";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_015595047.1 10 Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-2644606 "NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_024941647.1 3 Reactome: R-HSA-5576890;Reactome: R-HSA-1296072;Reactome: R-HSA-5576893 "Phase 3 - rapid repolarisation";"Voltage gated Potassium channels";"Phase 2 - plateau phase" XP_015585203.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015590014.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015589173.1 4 Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_015588598.1 8 Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_015594403.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015586695.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_015597439.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015610525.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_024945824.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_015589871.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_024936857.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_024944013.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_024941080.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024942952.1 5 Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189 "Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)" XP_015587650.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" XP_015592181.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015600617.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_015596537.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_024945841.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_015589073.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_024947654.1 13 Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509 "Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling" XP_015610321.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015606917.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024940826.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_015584785.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_024942666.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024945469.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015602804.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015603081.1 6 MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290 "Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_015605179.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_024940954.1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine" XP_015594246.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_024940624.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024937520.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_015598459.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024947508.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_024941897.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024943050.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_015600189.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024939468.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_024940513.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015587174.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_015604729.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_024942720.1 9 Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Macroautophagy" XP_024939750.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024940797.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024942664.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015592767.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Macroautophagy";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_015598711.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_024945312.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" XP_015602963.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_015604292.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015596955.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_015596825.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015603571.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_015585806.1 12 KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"G alpha (q) signalling events";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"NRAGE signals death through JNK";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015585114.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015590910.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015607242.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015585025.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015593630.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015591181.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_024942838.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015603272.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015606920.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_015605020.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_024935835.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_024942231.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015610198.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015595995.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_024937417.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024947653.1 13 Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356 "PLC beta mediated events";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Ion homeostasis";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion" XP_015610398.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015604845.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015592791.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_015596817.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015595070.1 6 Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653 "Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_015606238.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18 "Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015594859.1 29 Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-167200 "Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_015586837.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_015591752.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024943132.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_015598938.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015604730.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930 "ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor" XP_015600158.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015600479.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015609559.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis" XP_015606997.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_015601071.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_024946052.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_015610204.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015608626.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024939398.1 12 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015605955.1 6 KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate" XP_015588801.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_015596443.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015586601.1 14 Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-168333;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_024942123.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015585853.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_015603015.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015593707.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015598317.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_015605614.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_015602772.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_015591285.1 2 KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19 "Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis" XP_015585219.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015604969.1 5 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_015590425.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_015608243.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015610176.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015593614.1 4 Reactome: R-HSA-975144;Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex" XP_015589639.1 15 MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-7383;MetaCyc: PWY-7218 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_015598157.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_015599951.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_024945427.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015607568.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024943718.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_024947240.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015603198.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015594612.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_015587664.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_024937824.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015608634.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015602196.1 17 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9022692;Reactome: R-HSA-174178;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Regulation of MECP2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Human cytomegalovirus infection";"EML4 and NUDC in mitotic spindle formation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway" XP_015595537.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015600267.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616 "Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication" XP_015593789.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_015586672.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024938996.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015609741.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_015588503.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_024945686.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015594953.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-166208 "HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling" XP_024946217.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015585736.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024945285.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_015586732.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024936349.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015595721.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_024941249.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015609467.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015588700.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_015592724.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_024936017.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_024944368.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024945843.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_024942847.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015592927.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_015595861.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015593679.1 10 MetaCyc: PWY-922;MetaCyc: PWY-7571;MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7524 "Mevalonate pathway I";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression";"Mevalonate pathway III (archaea)" XP_015603872.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_024943882.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_024945741.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024936130.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015605442.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_015599332.1 58 Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5689901;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-8948751 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Metalloprotease DUBs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity" XP_024937234.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015609998.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_015599605.1 9 KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-6147 "Folate biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I" XP_024943200.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_024937727.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024938423.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_024941665.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015610412.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_015605124.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015598165.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024938015.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_015607933.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_024939658.1 11 Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108 "Circadian Clock";"Estrogen-dependent gene expression";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_015584765.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015604900.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015600567.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015588795.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015598514.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_015608530.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_015610354.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_024942651.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_024947435.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_015585808.1 12 Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015591712.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024937830.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015610189.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015600096.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015591600.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024938569.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_015585029.1 56 Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174178 "Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"UCH proteinases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015599278.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024947338.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024939749.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015603273.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024944231.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015604604.1 4 KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2 "Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015606409.2 1 Reactome: R-HSA-445355 "Smooth Muscle Contraction" XP_024936064.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015601358.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_015610148.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024946111.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024945445.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024936001.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015595451.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138 "Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" XP_015599446.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_015601571.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_024942390.1 4 Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015585693.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015589973.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015609109.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_015593698.1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_024943447.1 7 MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5466 "Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis" XP_024947270.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_015607751.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_015600134.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015585215.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_024943033.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_015599877.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024937856.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024940370.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_024945253.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015594663.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024945832.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_015604285.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_024937388.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015585689.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015597582.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_024941910.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015586596.1 9 Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-381340 "Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation" XP_015602633.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024947565.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_024937006.1 4 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-8849175 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism" XP_015592958.1 6 Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Circadian Clock";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024938907.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015605812.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_024941623.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_024947230.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024947535.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_015597554.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695 "Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation" XP_015606391.1 3 Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2 "Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism" XP_015609968.1 16 Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174178 "Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015607823.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015594512.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_024936249.1 6 MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol" XP_024942198.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_024946726.1 10 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6362;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_024945171.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_015608176.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024936076.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_024941728.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015584991.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_024943834.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015592420.1 17 MetaCyc: PWY-7221;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7176 "Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis" XP_015592378.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015602679.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_024945156.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015604367.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024944105.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015587334.1 12 MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5870 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" XP_024935468.1 13 MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-7384;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-5538 "Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI" XP_015610270.1 42 Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-69473;Reactome: R-HSA-5625886 "RNA Polymerase I Promoter Escape";"HCMV Late Events";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Amyloid fiber formation";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Meiotic synapsis";"HDACs deacetylate histones";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_024945070.1 4 Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906 "Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_015588830.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015595742.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015588848.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_015600951.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_024939631.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015604294.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015592388.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015585594.1 11 MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-2029485;MetaCyc: PWY-6453 "Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis" XP_024947543.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024938802.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015584907.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_015587089.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_015602794.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024942572.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_015584826.1 57 Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-532668;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-187577 "Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21" XP_015600108.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_015605422.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024943675.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024945617.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024936515.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015609800.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_024938862.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015592801.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_024944039.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024946295.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_015609219.1 5 KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336;MetaCyc: PWY-7180;Reactome: R-HSA-6798695;MetaCyc: PWY-8060 "Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation";"2-deoxy-D-ribose degradation I" XP_024947395.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015604534.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_024938663.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015595075.1 6 MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_024942845.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024943940.1 20 KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7176;Reactome: R-HSA-380320;MetaCyc: PWY-7205;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7210 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_015598173.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_024940252.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015590713.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015604789.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015604744.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015594051.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_015607279.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024935906.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015588589.1 7 KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205 "Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose" XP_015584711.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015591269.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015607793.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024942368.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_024939790.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-110381;Reactome: R-HSA-5685939;Reactome: R-HSA-5696397;Reactome: R-HSA-5649702 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_015592179.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015592918.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552 "Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin" XP_015596858.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_024937214.1 14 MetaCyc: PWY-6453;Reactome: R-HSA-75109;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483191 "Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Ether lipid metabolism";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC" XP_024943999.1 6 KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism" XP_024938347.1 8 KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171 "Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis" XP_024939260.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024943308.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015586239.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024941549.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_015595303.1 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_015596357.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015589086.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024936906.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_015599094.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_015601482.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_024937621.1 57 Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764 "ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling" XP_024936873.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_015599890.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015593858.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399 "Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_015598839.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_015599710.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015593790.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_015595229.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015588741.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015591283.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_024943747.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015588917.1 14 Reactome: R-HSA-6798695;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-1474228;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802 "Neutrophil degranulation";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3" XP_015590709.1 5 KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210 "Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Purine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_015597333.1 14 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2467813;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Separation of Sister Chromatids";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2" XP_024939771.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015608350.1 57 Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236 "Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_015605851.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_015599395.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015588365.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_015604957.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_024947509.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015605297.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015586422.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_015594042.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_024947248.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015586893.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism" XP_015595740.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024947797.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024946071.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015600171.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_024937675.1 2 Reactome: R-HSA-196843;Reactome: R-HSA-83936 "Vitamin B2 (riboflavin) metabolism";"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015597538.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952 "Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions" XP_024935782.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024939402.1 12 Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015589616.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015597809.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_015584730.1 14 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5656121 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI" XP_024936161.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015599144.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_015589588.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946 "Ion transport by P-type ATPases";"Ion homeostasis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants" XP_024946350.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015594220.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015605176.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_024945200.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015607454.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_015598453.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_024943676.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024946988.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015603419.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024947747.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_015599581.1 5 MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis" XP_024937235.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015589977.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_015598572.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024942635.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015609181.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015602398.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_024947741.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_015598174.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_024944192.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_015597504.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_024946817.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_015592402.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015606086.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015588318.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015597488.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_015603431.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015600410.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_024939176.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015595819.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024940407.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_015603868.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_024938858.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015604971.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015594794.1 7 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862 "PPARA activates gene expression";"Generic Transcription Pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_024938787.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_015610353.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015595738.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024947247.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024935800.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_024940553.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015609764.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_015596244.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015591576.1 4 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing" XP_015598709.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_024945529.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015607384.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_015587407.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_024942604.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015604557.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_024936327.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_015602289.1 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6 "beta-Alanine metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism" XP_015604923.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015609919.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024935504.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_015610175.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_015601380.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024938834.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015604838.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_015604844.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024935956.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_015599660.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_024936883.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_015590292.1 3 MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987 "Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis" XP_024942599.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015590718.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_015596546.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024946500.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024940432.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015604049.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015587454.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015605759.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_015588082.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024945858.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_015586969.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_015607578.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_024945284.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_024936106.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway" XP_015607292.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_024936191.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_024936686.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_024940409.1 16 Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-194840;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-1660499;Reactome: R-HSA-6811558 "Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"Rho GTPase cycle";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Synthesis of PIPs at the plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_015605470.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_015607294.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_015603143.1 10 MetaCyc: PWY-5022;MetaCyc: PWY-6537;MetaCyc: PWY-6536;KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;KEGG: 00410+2.6.1.19;Reactome: R-HSA-916853;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6535 "4-aminobutanoate degradation V";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"Propanoate metabolism";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"beta-Alanine metabolism";"Degradation of GABA";"Butanoate metabolism";"4-aminobutanoate degradation I" XP_015591878.1 3 KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691 "Purine metabolism";"Caffeine metabolism";"Urate conversion to allantoin I" XP_015597505.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015587311.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024944623.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015609857.1 13 MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1 "Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes" XP_024944017.1 10 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-5689880;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"HATs acetylate histones";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_024941510.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015587845.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_024936711.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_024945829.1 33 Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746 "RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein" XP_024946987.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015590934.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_024936378.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015600631.1 12 MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-6978;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-6708 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_024941618.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_015595949.1 10 MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7199;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210;Reactome: R-HSA-69205;MetaCyc: PWY-3841;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleosides salvage";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_015589357.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_024939961.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024936973.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024939450.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024947421.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_015602151.1 7 Reactome: R-HSA-4086400;Reactome: R-HSA-5663220;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598 "PCP/CE pathway";"RHO GTPases Activate Formins";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins" XP_015587410.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015586774.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_015605608.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_015608262.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015590023.1 7 KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism" XP_015598753.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_015587378.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015599099.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_015594405.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015593264.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_024942713.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015590919.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_015598547.1 4 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-8866427 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation" XP_015593608.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_015593273.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_015598441.1 3 MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis" XP_015593140.1 18 MetaCyc: PWY-8053;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-8051 "Anandamide biosynthesis II";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Acyl chain remodelling of PC";"Anandamide biosynthesis I" XP_015598942.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015595140.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015593094.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_024939636.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024943125.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015601693.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015590903.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015604278.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024939664.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" XP_024939211.1 5 Reactome: R-HSA-9609523;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_015608033.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_015590445.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_015609620.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_024936172.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024942185.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_015586257.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015594542.1 11 KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"Human cytomegalovirus infection";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"p38MAPK events";"mTOR signaling pathway" XP_015595304.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024947358.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024945845.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_015594777.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015609515.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024940676.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015598674.1 6 MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663 "Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I" XP_024943165.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_015598527.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_015588672.1 57 Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-69481 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints" XP_015599796.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024938234.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015589210.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024937359.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015599530.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_015601119.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_015586782.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_015606956.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015589997.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_024936329.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015609409.1 12 MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857 "L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Lupulone and humulone biosynthesis";"Pyruvate metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis" XP_015589920.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015606043.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024941656.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015591569.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015609287.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_015607237.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015586579.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024936790.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015591199.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_024938863.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024941010.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015607795.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015590300.1 6 Reactome: R-HSA-194840;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368 "Rho GTPase cycle";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation" XP_024946891.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_024945277.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_024936125.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_024937031.1 10 MetaCyc: PWY-6362;Reactome: R-HSA-1855204;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-4661;MetaCyc: PWY-6366;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.159;Reactome: R-HSA-983231;MetaCyc: PWY-6365 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Factors involved in megakaryocyte development and platelet production";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis" XP_024939492.1 4 MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis" XP_024938449.1 11 Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015605380.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE" XP_015594706.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_015587456.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015596395.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015599536.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015594228.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_024942089.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015596493.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_024945593.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024946888.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_024942770.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015596053.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015591237.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015587429.1 33 Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377 "Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins" XP_015601700.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015609850.1 3 MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0 "Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III" XP_015594251.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_024945536.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_024935959.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_015610400.1 8 MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826 "Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Surfactant metabolism" XP_024938725.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024946577.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024944674.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015606480.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024944856.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_015589037.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_024947824.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015594568.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_015599960.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_024937119.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_015593262.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_015589221.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015608394.1 19 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-5419276;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-5389840;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-5368286;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Mitochondrial translation termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Mitochondrial translation elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Mitochondrial translation initiation";"Peptide chain elongation" XP_024942911.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_015595463.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_015602202.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_015600193.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_015595672.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015591533.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015592375.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024947448.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis" XP_015603699.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015591958.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_015593422.1 9 Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_015590230.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC" XP_024940988.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_024942019.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_015608425.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015605081.1 7 Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-165054 "MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA" XP_015599060.1 6 Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "mRNA Splicing - Major Pathway";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_015596977.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_015609522.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_015601231.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_024945574.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015594160.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024940868.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015602295.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015589585.1 5 MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16 "CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism" XP_015598175.1 5 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs" XP_015595300.1 8 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_024941550.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_015606302.1 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539 "Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism" XP_015593640.1 8 MetaCyc: PWY-7817;MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148;KEGG: 04658+3.1.3.16 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG";"Th1 and Th2 cell differentiation" XP_024944617.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015590685.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_015593680.1 10 MetaCyc: PWY-7391;KEGG: 00900+2.3.3.10;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7524 "Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Valine, leucine and isoleucine degradation";"Mevalonate pathway III (archaea)" XP_024938875.1 8 MetaCyc: PWY-7979;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633 "Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_024943490.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015592683.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024941068.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015607930.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619 "Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis" XP_015587067.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015599600.1 15 Reactome: R-HSA-9665247;Reactome: R-HSA-9665249;Reactome: R-HSA-9665251;Reactome: R-HSA-9665250;Reactome: R-HSA-9665233;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-9665246;Reactome: R-HSA-5637810;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9665244;Reactome: R-HSA-9634285;Reactome: R-HSA-9665245 "Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by EGFRvIII";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib" XP_024935741.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015600041.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024942334.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015605373.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015603351.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024940765.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015593699.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015608395.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015607666.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-69017 "Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6" XP_015603010.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024939784.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015603533.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_024946856.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015601823.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_015587790.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_024938156.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015585652.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_024940379.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_015593460.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_024940488.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_015609417.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_015608206.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_024946589.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024944499.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024943106.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015587062.1 10 MetaCyc: PWY-6362;MetaCyc: PWY-4661;MetaCyc: PWY-6366;Reactome: R-HSA-1855204;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855167;Reactome: R-HSA-983231;MetaCyc: PWY-6365;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.159 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"Factors involved in megakaryocyte development and platelet production";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system" XP_015599456.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015595343.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024943057.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_024940944.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_024938150.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024940439.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_024938806.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015595664.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174430 "Removal of the Flap Intermediate";"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Polymerase switching";"Telomere C-strand synthesis initiation" XP_024942596.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_024947545.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015600950.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_015601915.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_015606053.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015591807.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_015586314.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_024947340.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015596052.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015591541.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_015590806.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015608232.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_015608736.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-196025 "Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions" XP_015599949.1 16 Reactome: R-HSA-1257604;Reactome: R-HSA-9020702;Reactome: R-HSA-1810476;Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-209543;Reactome: R-HSA-975155;Reactome: R-HSA-3134963;Reactome: R-HSA-975110;Reactome: R-HSA-5603041 "PIP3 activates AKT signaling";"Interleukin-1 signaling";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"p75NTR recruits signalling complexes";"MyD88 dependent cascade initiated on endosome";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)" XP_024941407.1 9 Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783 "Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type" XP_015596655.1 33 Reactome: R-HSA-6782135;Reactome: R-HSA-69202;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-69656;Reactome: R-HSA-69231;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-69273;Reactome: R-HSA-167158;Reactome: R-HSA-8939236 "Dual incision in TC-NER";"Cyclin E associated events during G1/S transition";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin D associated events in G1";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the HIV-1 Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_015585008.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_024943019.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_015587624.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015595164.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription" XP_015594431.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015607767.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015605943.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024935598.1 13 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928663;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human papillomavirus infection";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse";"PI3K-Akt signaling pathway";"Thermogenesis" XP_024937238.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_024938214.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-877300 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion homeostasis";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling" XP_024947791.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024946898.1 14 MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724 "Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_015584726.1 9 Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-1362277 "Activation of the pre-replicative complex";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Transcription of E2F targets under negative control by DREAM complex" XP_015606000.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_024940790.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015597587.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_015588982.1 13 MetaCyc: PWY-7821;MetaCyc: PWY-7184;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;KEGG: 00760+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9 "Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Starch and sucrose metabolism" XP_015587713.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108 "RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_015586588.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_015609671.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion" XP_015588375.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015604530.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024937245.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_024937088.1 2 Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"Formation of apoptosome" XP_024942077.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15 "Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_015585118.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024939710.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015603700.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_024943128.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_024945564.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015593499.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015608766.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015602791.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024942333.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_024947732.1 1 Reactome: R-HSA-977225 "Amyloid fiber formation" XP_015604200.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_024936806.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_015598169.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015592313.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_015608442.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015593190.1 5 Reactome: R-HSA-9646399;Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-977225 "Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Amyloid fiber formation" XP_024939469.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_015587558.1 7 MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897 "Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes" XP_024943691.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_024936237.1 8 KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171 "Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis" XP_015606478.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024940336.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015600334.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024942848.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015591009.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_015601272.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015586412.1 7 Reactome: R-HSA-1483191;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7818;MetaCyc: PWY-7886 "Synthesis of PC";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis" XP_024946862.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015601105.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024936102.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_024938160.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_015600564.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024936852.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_015588952.2 2 Reactome: R-HSA-196843;Reactome: R-HSA-83936 "Vitamin B2 (riboflavin) metabolism";"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015604045.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015600972.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015589087.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015597067.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024947245.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024943008.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024946433.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015589421.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_015606870.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_024944592.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_015588576.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation" XP_015608622.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015596455.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_024941975.1 11 Reactome: R-HSA-4043916;MetaCyc: PWY-3861;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-7586 "Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_015600734.1 6 MetaCyc: PWY-5941;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238;MetaCyc: PWY-6737;Reactome: R-HSA-70221 "Glycogen degradation II";"Starch degradation III";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation V";"Glycogen breakdown (glycogenolysis)" XP_015610079.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_024945240.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024936247.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015605292.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_015608604.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_024943784.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_015586970.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_015600673.1 3 KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis" XP_015591581.1 10 MetaCyc: PWY-7921;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;Reactome: R-HSA-162699;MetaCyc: PWY-7661;MetaCyc: PWY-7922;Reactome: R-HSA-4719360;MetaCyc: PWY-7979;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377 "Protein O-mannosylation I (yeast)";"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_015596384.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_024943170.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_015599955.2 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_015608863.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_015592171.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015608193.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024941250.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_024936071.1 4 MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803 "Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing" XP_024935828.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015587724.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_015595890.1 9 KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11 "Inositol phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system" XP_015591280.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015586160.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_015600100.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024947437.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_015609702.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_024943540.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164 "MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade" XP_015599404.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015590455.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015606998.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_015605026.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_015598564.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_024945955.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024945890.1 12 KEGG: 00230+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4 "Purine metabolism";"Purine metabolism";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfite oxidation III";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Selenocompound metabolism" XP_015598899.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_024938215.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952 "CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion homeostasis";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"RAF activation";"Signaling by BRAF and RAF fusions" XP_015604915.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015609835.1 22 Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257 "CTLA4 inhibitory signaling";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion" XP_015607686.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024946576.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024944197.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024940385.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_015586578.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024936367.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_015608648.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015606611.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024935873.1 6 Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606 "Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_015586812.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024939037.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_024936983.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015607534.1 8 Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_015589297.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_024936642.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_024944532.1 6 KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122 "Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis" XP_024946917.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_024944699.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483 "Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)" XP_015608524.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_024946761.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015596196.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024937936.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015607908.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_024938233.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015596446.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_024943804.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024943996.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024936684.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_015604835.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_015598223.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015602674.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024939381.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024939467.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_015610386.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_015604558.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_024943760.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024940450.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_015595640.1 7 Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472 "Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"HCMV Early Events";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_015589001.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024945072.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;MetaCyc: PWY-6517;Reactome: R-HSA-446210 "Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine" XP_024938213.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946 "Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Ion homeostasis";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants" XP_015606276.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024947547.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_015600271.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689 "Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_024947221.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467 "Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs" XP_015589139.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_024946734.1 4 MetaCyc: PWY-8026;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047 "Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol" XP_015607755.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_024940446.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_024936537.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_015598550.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_024942864.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_015598744.1 8 KEGG: 00350+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-5049;Reactome: R-HSA-209905;KEGG: 00950+1.14.16.2;MetaCyc: PWY-3581 "Tyrosine metabolism";"(S)-reticuline biosynthesis II";"Folate biosynthesis";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"Catecholamine biosynthesis";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis I" XP_015605127.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024946850.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_024946606.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_015595487.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024936052.1 52 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-73780;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-167242;Reactome: R-HSA-427413;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-73980;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-168325 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NoRC negatively regulates rRNA expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Termination";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis" XP_015598222.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015593655.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024945321.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024939146.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_015591200.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_015606042.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_024936139.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015606392.1 3 Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2 "Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism" XP_015587678.1 5 Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism" XP_015584758.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1" XP_015592198.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015607566.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015599385.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" XP_015594392.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_015587973.1 9 MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142;Reactome: R-HSA-196780;Reactome: R-HSA-70263 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"Gluconeogenesis" XP_015592354.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_024937302.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_015607172.1 10 Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328 "Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" XP_015588636.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_015593909.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015598788.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015589896.1 4 Reactome: R-HSA-5633231;MetaCyc: PWY-5629;Reactome: R-HSA-446193;KEGG: 00311+1.21.3.1 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Isopenicillin N biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Penicillin and cephalosporin biosynthesis" XP_024946588.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015607429.1 7 Reactome: R-HSA-8856828;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36 "Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system" XP_024937290.1 7 KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism" XP_024936083.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015605674.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015593041.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015590301.1 6 KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36 "Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_015586743.1 6 Reactome: R-HSA-9028731;Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706 "Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling" XP_015597490.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_024940175.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_024947780.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024943238.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024940208.1 5 MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-922 "Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I" XP_015594580.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_015607695.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015585662.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015592856.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_024944007.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids" XP_024944178.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015593896.1 18 Reactome: R-HSA-6796648;Reactome: R-HSA-5693568;MetaCyc: PWY-7511;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5689901;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565 "TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Protein ubiquitination";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Metalloprotease DUBs";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015585772.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015587489.1 8 Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"HCMV Early Events";"Transcriptional Regulation by E2F6" XP_024940214.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015588606.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015589584.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_024942215.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_015609841.1 1 Reactome: R-HSA-419771 "Opsins" XP_015588922.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015601760.1 7 KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-7255;MetaCyc: PWY-8043;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2 "Glutathione metabolism";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism" XP_015595597.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_024944312.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015605239.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_024945079.1 3 Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383 "Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation" XP_024944534.1 6 Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290 "O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_015602240.1 12 KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053 "Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II" XP_024940367.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_024946045.1 14 Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169 "Translesion synthesis by POLK";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis" XP_015604397.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024937571.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_015604972.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015589046.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024938703.1 5 KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)" XP_024938181.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins" XP_024947534.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_024940408.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_015606755.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_015599609.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_015604363.1 6 MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273 "Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" XP_024941639.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_015596509.2 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_024940412.1 16 Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-1660499;Reactome: R-HSA-8853659;Reactome: R-HSA-512988;Reactome: R-HSA-194840;Reactome: R-HSA-1266695;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-9009391 "Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Synthesis of PIPs at the plasma membrane";"RET signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Rho GTPase cycle";"Interleukin-7 signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling" XP_015603925.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_024944890.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024938597.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015602011.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_015604181.1 4 MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II" XP_015597728.1 17 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation" XP_015600894.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024938063.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024945073.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517 "Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II" XP_015594979.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015599902.1 4 Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255 "HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis" XP_024946921.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability" XP_015605571.1 4 Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1" XP_024942367.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_015588061.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024945644.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_024947773.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024947487.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015593333.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"mTOR signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_024941003.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015609248.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015596818.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024942959.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015598764.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430 "Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_015596287.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_015585777.1 3 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019;Reactome: R-HSA-71336 "Pyrimidine metabolism";"Pseudouridine degradation";"Pentose phosphate pathway" XP_015603509.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015587414.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024945800.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015586632.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015599436.1 4 Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516 "Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin" XP_015587374.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024945515.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015584752.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_015609584.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_024944179.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_024935829.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015585826.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015591531.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024947558.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607878.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_024943016.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_015588374.1 6 KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_024935998.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024937955.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024944235.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015591577.1 18 Reactome: R-HSA-70263;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690 "Gluconeogenesis";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"TCA cycle II (plants and fungi)" XP_015591427.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015605190.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015601138.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_015598214.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015602852.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015605878.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041 "Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis" XP_015601896.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015590031.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_024941606.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_024944407.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024947584.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_015600772.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_024938835.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024942208.1 8 KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268 "Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Pyruvate metabolism" XP_015604365.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015595859.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_015591536.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015584774.1 5 Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109 "Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_015589785.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_024938804.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015589111.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015601767.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_015594142.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015591354.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015606893.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_024940339.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015586184.1 11 Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-2029482;Reactome: R-HSA-983231 "RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"Cyclin D associated events in G1";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production" XP_015585937.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery" XP_015585116.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024944180.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_024941664.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024938242.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_024941361.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_015605358.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024937289.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2 "Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism" XP_015593066.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_024938408.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_015601177.1 3 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_015586079.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_024943856.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015588632.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_024938424.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_024946964.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015585671.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015607824.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015590237.1 3 KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_024944637.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015610415.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_015594860.1 29 Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167161 "Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation" XP_015590792.1 11 Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Macroautophagy" XP_015596195.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015594857.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_015587063.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024935821.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_015598758.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676 "Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_015585461.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_024938460.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_024938427.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_015604116.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015610384.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions" XP_015585206.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024945720.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015592851.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_024938808.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015597203.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024945620.1 8 Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69183 "Telomere C-strand synthesis initiation";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand" XP_015598543.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015606810.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024946069.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015609433.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway" XP_015602995.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_015589199.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_015585457.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015598786.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015588739.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015586259.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024942926.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_015586459.1 10 Reactome: R-HSA-72702;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-382556;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72731;Reactome: R-HSA-381042;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ABC-family proteins mediated transport";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Recycling of eIF2:GDP";"PERK regulates gene expression";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015591999.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015586550.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024947763.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015585115.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024945107.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024937532.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_024943492.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_024940914.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015603183.1 20 MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6 "Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Fatty acid degradation" XP_015603963.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015586310.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607 "G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends" XP_015601589.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015604046.1 3 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" XP_024938180.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024942910.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_024946895.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_015595638.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_024945956.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_024946591.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015591306.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015590021.1 7 MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11 "2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system" XP_015607981.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015608743.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024936563.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015594465.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015608767.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024940169.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015606859.1 29 Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-912446;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-3108214;Reactome: R-HSA-3371511;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-68962;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-6783310;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-5693616 "G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Meiotic recombination";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA damage response and repair proteins";"HSF1 activation";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Activation of the pre-replicative complex";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Fanconi Anemia Pathway";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_015603782.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024940506.1 11 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015610397.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_024937355.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015591350.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015592578.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_015602956.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_024940963.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_015605615.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_015586595.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206 "Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha" XP_024944177.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015603737.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015587284.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024944528.1 20 MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6 "Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid degradation" XP_015595141.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015598775.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_015587875.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015607829.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_015605399.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_015601592.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_024944783.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024943867.1 4 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_015602178.1 33 Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-180746 "Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Mitotic Prometaphase";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein" XP_024945128.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_024938174.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport" XP_015593025.1 3 Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50 "MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_015585694.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024947570.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015586474.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_015607868.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_024940951.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_015592444.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_015601723.1 7 MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I" XP_015587239.1 14 KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-75109;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Ether lipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Plasmalogen biosynthesis";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis I" XP_024943174.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_015602451.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024943390.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_015586020.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015598650.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015600039.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_015590827.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024939640.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015602636.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015606252.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024947542.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024937979.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024940916.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015596980.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015601824.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_015603910.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_015605953.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_024935519.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_024935960.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015597687.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_015591117.1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_015605849.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015603283.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_024945320.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015597574.1 5 KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661 "Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation" XP_015599905.1 18 MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7221 "UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis" XP_015601553.1 16 Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery" XP_015585242.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_024941079.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024945755.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015594619.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_024938097.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015596240.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015604172.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015599350.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" XP_015586542.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015599831.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_015596774.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015589358.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_015587955.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_024936377.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024936967.1 5 KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-7279 "Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)" XP_015602239.1 12 MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_015585227.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015604842.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015586420.1 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" XP_024941064.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015598630.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" YP_002889385.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015584996.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane" XP_015599227.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_024938764.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015589595.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946 "Ion transport by P-type ATPases";"Ion homeostasis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants" XP_015604589.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_015603779.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015599942.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015600013.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015586258.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015590262.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015604438.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway" XP_015605910.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-1834949 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_015597664.1 13 Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101 "Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation" XP_024939551.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_024946706.1 16 MetaCyc: PWY-1622;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-6886;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-2221 "Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_015593514.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015605609.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_015607826.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015596204.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_024938592.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015585642.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_024941588.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_024945667.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_015604323.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015599468.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024936884.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_024938207.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324 "Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_024945453.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024942049.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015610035.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024946982.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024937044.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_015605534.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015605350.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015610586.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024942543.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_024947536.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_015603194.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-8939243;Reactome: R-HSA-2559580 "Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence" XP_015585944.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015595182.1 8 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling by Hippo";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_024938843.1 22 Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221 "Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Negative regulation of MAPK pathway" XP_015593898.1 18 Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5689901;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;MetaCyc: PWY-7511;Reactome: R-HSA-6796648 "SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Metalloprotease DUBs";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Protein ubiquitination";"TP53 Regulates Transcription of DNA Repair Genes" XP_015586099.1 7 Reactome: R-HSA-5685939;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-110362 "HDR through MMEJ (alt-NHEJ)";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair" XP_024942667.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015603278.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015604098.1 5 KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300 "Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA" XP_024947325.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024947515.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015588169.1 5 MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692 "Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation" XP_015603505.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024936902.1 5 Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012 "Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_015589436.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015593721.2 7 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy" XP_015585340.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15 "Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_015590061.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015597079.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024940775.1 8 Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_015601357.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_015607302.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024937395.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015595361.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015609117.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_015595172.1 2 Reactome: R-HSA-8849473;Reactome: R-HSA-6791226 "PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015596785.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015605402.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024936715.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015586110.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015599289.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015608830.1 4 Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Cristae formation";"Mitochondrial protein import" XP_024938838.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_024937972.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015587165.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015601229.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_015584888.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_015586177.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024944864.1 5 KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22 "Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism" XP_015603427.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015599073.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015608615.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015604515.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015607106.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024938864.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015597629.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015588618.1 10 Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_015597205.1 6 Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-73863 "RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_015607958.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015597019.1 3 Reactome: R-HSA-5576893;Reactome: R-HSA-1296072;Reactome: R-HSA-5576890 "Phase 2 - plateau phase";"Voltage gated Potassium channels";"Phase 3 - rapid repolarisation" XP_024940512.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015597900.2 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification" XP_024943420.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_015589476.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy" XP_024943357.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_024941627.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920 "Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability" XP_015596210.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015586645.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024936333.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015601247.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015604873.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015585698.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_015587168.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_015602559.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_024938450.1 11 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway" XP_024940736.1 6 MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;Reactome: R-HSA-196807 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism" XP_015595585.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015595448.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015599398.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015603702.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015592797.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_015598371.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015588543.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024935935.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015589645.1 11 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949 "Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)";"Human papillomavirus infection";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA" XP_024944678.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015593513.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_024936538.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_015585511.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015587855.1 2 MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_015609904.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221 "AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Negative regulation of MAPK pathway" XP_015607293.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015588681.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440 "Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_015601249.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_015601377.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015604552.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024943043.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050 "Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_015586683.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_024938144.1 7 MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11 "2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system" XP_015588336.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015590010.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024940338.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024944468.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_024935789.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015608393.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_015588270.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_015610123.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015596739.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024940195.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation" XP_024940484.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_015584858.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015592403.1 25 Reactome: R-HSA-8931987;Reactome: R-HSA-8949275;Reactome: R-HSA-8939246;Reactome: R-HSA-8877330;Reactome: R-HSA-8939245;Reactome: R-HSA-8939243;Reactome: R-HSA-8940973;Reactome: R-HSA-8941332;Reactome: R-HSA-8936459;Reactome: R-HSA-8951936;Reactome: R-HSA-8941284;Reactome: R-HSA-8939236;Reactome: R-HSA-8939242;Reactome: R-HSA-8939247;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-8941333;Reactome: R-HSA-8941326;Reactome: R-HSA-8941858;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-8951911;Reactome: R-HSA-8939256;Reactome: R-HSA-8934593;Reactome: R-HSA-8935964 "RUNX1 regulates estrogen receptor mediated transcription";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 regulates p14-ARF";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates bone development";"Regulation of RUNX3 expression and activity";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in WNT signaling";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates expression of components of tight junctions" XP_024942510.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015601728.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015586661.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024937120.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_024939795.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_024945398.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024944952.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015607165.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_015602160.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015586077.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport" XP_024941676.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_015587314.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015598298.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_024942387.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015585665.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015586173.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-499943;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3 "Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism" XP_024944874.1 4 Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-9615017 "AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_015596536.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_024941912.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015596283.1 16 Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580 "Regulation of PTEN mRNA translation";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence" XP_024936039.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015585635.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015587339.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_024941671.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015604037.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_024938914.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015595784.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_024945069.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015585871.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_015602282.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_015597547.1 9 Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608 "Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation" XP_015599324.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Ion channel transport";"Amino acids regulate mTORC1" XP_015606184.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_024938147.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015594796.1 7 Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-212436;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-381340 "PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation" XP_015591431.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015602850.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024940345.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024939038.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_015588463.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024941103.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015610129.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015593413.1 9 Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351 "PLC beta mediated events";"Inositol phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_024942154.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015609678.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-381676 "Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_024945834.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_024942471.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_024939142.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024939817.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015607503.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_015599086.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_015609845.1 22 Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated" XP_015595921.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024939820.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015593487.1 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_015590304.1 6 KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368 "Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation" XP_024946036.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_024942912.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_024941252.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015589363.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_024938513.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015603780.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024939718.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_024940777.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_015608996.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)" XP_015604850.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_024938753.1 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181 "Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism" XP_024939374.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024935887.1 9 Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-5981 "Synthesis of PA";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III" XP_024946466.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_024936177.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015586210.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015591725.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015600293.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024943397.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024945017.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015584860.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_015603740.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024940335.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015604383.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" XP_024938235.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024941703.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_024940467.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015591822.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_024944889.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024936287.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024943710.1 6 MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221 "Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_024946835.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_015607877.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_015601139.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_015593494.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015601557.1 16 Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery" XP_015609710.1 5 Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211976 "Xenobiotics";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Endogenous sterols" XP_015587699.1 17 Reactome: R-HSA-74259;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6644;MetaCyc: PWY-6627;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-6620;MetaCyc: PWY-6608;Reactome: R-HSA-6798695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6609;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1 "Purine catabolism";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Purine metabolism" XP_015596062.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_024943440.1 14 KEGG: 00770+2.6.1.42;MetaCyc: PWY-5057;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5104;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5103;MetaCyc: PWY-5108;Reactome: R-HSA-70895;MetaCyc: PWY-5078;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5076 "Pantothenate and CoA biosynthesis";"L-valine degradation II";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis IV";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis V";"Branched-chain amino acid catabolism";"L-isoleucine degradation II";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation III" XP_024942190.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_015594250.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_015591101.1 8 Reactome: R-HSA-5083633;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5083629 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_024939567.1 29 Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation" XP_024947279.1 18 KEGG: 00400+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;MetaCyc: PWY-6638;MetaCyc: PWY-5913 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)" XP_015606384.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_015595160.1 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection" XP_015596831.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024947264.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024946463.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_024935554.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_015601253.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_015607196.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_015604057.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015592937.1 7 MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-7625 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)" XP_015598361.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_024935680.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_024938172.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_015597198.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_015609127.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015596639.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169 "Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis" XP_024938056.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015598141.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_015605151.1 7 Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80 "Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism" XP_015588699.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757 "Dual incision in TC-NER";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation" XP_024940983.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_015605209.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024943171.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_015591481.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_015598489.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_015610017.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_024936869.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015592888.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015587612.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_024947261.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015596284.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692 "Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity" XP_015586415.1 7 KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7818;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7782 "Glycerophospholipid metabolism";"Synthesis of PE";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis" XP_015590190.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015605780.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_024947253.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024943014.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_015585936.1 14 Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-113418 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex" XP_024943582.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_015607869.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041 "Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" XP_024945456.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015609157.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015595320.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015596541.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_015592093.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015594253.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_015591734.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015601790.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015595550.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_024947768.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015587016.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024945758.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015589772.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_024941581.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015592793.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_024943463.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015589168.1 27 Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-77588;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-975956;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-191859;Reactome: R-HSA-167152;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-111367;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159230;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-72203 "RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"snRNP Assembly";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP Dependant Mature mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Capped Intron-Containing Pre-mRNA" XP_015603359.1 2 KEGG: 00561+2.3.1.274;MetaCyc: PWY-5981 "Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III" XP_024939559.1 10 KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-4041 "Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle" XP_015609939.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015585122.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_015601784.1 20 MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-6545;Reactome: R-HSA-380320;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;Reactome: R-HSA-380270;KEGG: 00240+2.7.4.6 "Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of NuMA to mitotic centrosomes";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine metabolism" XP_015599041.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_024938332.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_015594092.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_024943700.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015590324.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015591216.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024938752.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024937948.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015588329.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015585735.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024942122.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015605965.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_015587951.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_024946719.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015591556.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015607565.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015592359.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation" XP_024940982.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_024943391.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_015587651.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" XP_024944641.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015609958.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015608348.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_015596889.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_015600246.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones" XP_024942601.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015589547.1 4 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis" XP_015586951.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024935697.1 5 Reactome: R-HSA-9033500;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782 "TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis" XP_015589898.1 2 MetaCyc: PWY-5629;KEGG: 00311+1.21.3.1 "Isopenicillin N biosynthesis";"Penicillin and cephalosporin biosynthesis" XP_024936509.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015605474.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_015587178.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_015591729.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024944662.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024941677.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_015605158.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_024938871.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_015606385.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_015599268.1 11 Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Circadian Clock";"RMTs methylate histone arginines";"RORA activates gene expression" XP_015593883.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015603027.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_015593934.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-202424 "G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"UCH proteinases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling" XP_015598588.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024936765.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" XP_015585949.1 12 Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_024940817.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024940923.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024939873.1 18 MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482925 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG" XP_015608318.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024937975.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015591197.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024940333.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015587093.1 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation" XP_024936622.1 11 Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213 "Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"Myogenesis";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs" XP_015600633.1 12 MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;MetaCyc: PWY-5857;MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39 "Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_015588930.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015602590.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015586883.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015602900.1 39 Reactome: R-HSA-190322;Reactome: R-HSA-5654732;Reactome: R-HSA-5654706;Reactome: R-HSA-190373;Reactome: R-HSA-190372;Reactome: R-HSA-5654227;Reactome: R-HSA-5654710;Reactome: R-HSA-5658623;Reactome: R-HSA-1839130;Reactome: R-HSA-2219530;Reactome: R-HSA-5654720;Reactome: R-HSA-190375;Reactome: R-HSA-109704;Reactome: R-HSA-2033514;Reactome: R-HSA-1257604;Reactome: R-HSA-5654688;Reactome: R-HSA-5654221;Reactome: R-HSA-5654704;Reactome: R-HSA-5654228;Reactome: R-HSA-5654719;Reactome: R-HSA-5654712;Reactome: R-HSA-5654727;Reactome: R-HSA-190371;Reactome: R-HSA-5654693;Reactome: R-HSA-5654726;Reactome: R-HSA-5655302;Reactome: R-HSA-5654733;Reactome: R-HSA-5654687;Reactome: R-HSA-5654695;Reactome: R-HSA-5654700;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-5654219;Reactome: R-HSA-5655253;Reactome: R-HSA-2033519;Reactome: R-HSA-5654699;Reactome: R-HSA-1839122;Reactome: R-HSA-5654689;Reactome: R-HSA-8853338 "FGFR4 ligand binding and activation";"Negative regulation of FGFR3 signaling";"FRS-mediated FGFR3 signaling";"FGFR1c ligand binding and activation";"FGFR3c ligand binding and activation";"Phospholipase C-mediated cascade, FGFR3";"PI-3K cascade:FGFR3";"FGFRL1 modulation of FGFR1 signaling";"Signaling by activated point mutants of FGFR3";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI-3K cascade:FGFR4";"FGFR2c ligand binding and activation";"PI3K Cascade";"FGFR3 mutant receptor activation";"PIP3 activates AKT signaling";"SHC-mediated cascade:FGFR1";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR3";"Phospholipase C-mediated cascade, FGFR4";"SHC-mediated cascade:FGFR4";"FRS-mediated FGFR4 signaling";"Negative regulation of FGFR2 signaling";"FGFR3b ligand binding and activation";"FRS-mediated FGFR1 signaling";"Negative regulation of FGFR1 signaling";"Signaling by FGFR1 in disease";"Negative regulation of FGFR4 signaling";"Downstream signaling of activated FGFR1";"PI-3K cascade:FGFR2";"FRS-mediated FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Phospholipase C-mediated cascade: FGFR1";"Signaling by FGFR2 in disease";"Activated point mutants of FGFR2";"SHC-mediated cascade:FGFR2";"Signaling by activated point mutants of FGFR1";"PI-3K cascade:FGFR1";"Signaling by FGFR3 point mutants in cancer" XP_024942156.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015608284.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024942096.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide" XP_015598578.1 6 MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism" XP_015588348.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_015596979.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_015610442.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015610181.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024944640.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015603442.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024938414.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_015607692.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015598669.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015598271.1 14 KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-3781;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254 "Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)" XP_015592473.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_015584855.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015586696.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_015603197.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015597938.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015596895.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024942161.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_015606811.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015591209.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_015585415.1 18 Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-167158 "RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex" XP_024941309.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015602375.1 9 KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00270+2.6.1.5;KEGG: 00960+2.6.1.5 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine catabolism";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis" XP_015590223.1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015599038.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_015595745.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015594471.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015588351.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015606327.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024942345.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_015586891.1 4 Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10 "Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015602638.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015595453.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138 "Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" XP_015598255.1 11 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport" XP_015604047.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_024946625.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015588585.1 7 MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8 "Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism" XP_015591100.1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_015605396.1 20 Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5685942 "Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)" XP_024939212.1 5 Reactome: R-HSA-9609523;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015609955.1 13 KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572 "Human immunodeficiency virus 1 infection";"EPHB-mediated forward signaling";"Human papillomavirus infection";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse" XP_024943423.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_024946607.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_015585778.1 3 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70;Reactome: R-HSA-71336 "Pseudouridine degradation";"Pyrimidine metabolism";"Pentose phosphate pathway" XP_015585787.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_024940905.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024939707.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015587803.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_024937774.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015594570.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_024943252.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_015608746.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_015587481.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015603614.2 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_024944366.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015602539.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015596102.1 11 KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-5381;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-7821 "Purine metabolism";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Tunicamycin biosynthesis" XP_015606005.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_024945879.1 24 Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-9619483 "EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs" XP_015596239.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015607410.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015606130.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015607946.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-8041 "Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis" XP_015590557.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015607406.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_024942788.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015593261.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_015602199.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024944466.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_015605070.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_024940921.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024942191.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_015590849.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_015605682.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015606213.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015594643.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_024947475.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015585608.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_015605067.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_015603039.1 7 MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00240+3.5.2.3;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698;MetaCyc: PWY-5697;MetaCyc: PWY-7791 "UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"UMP biosynthesis III" XP_024946842.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024936215.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015601024.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024944909.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015597040.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_015597948.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024946808.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015588629.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015596375.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_015589975.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015594348.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024946722.1 10 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6362;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_015592355.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015587712.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-191859 "Circadian Clock";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly" XP_024940515.1 4 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import";"Mitochondrial translation elongation" XP_015606234.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015586147.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015606033.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_024943074.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_015593605.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_024940511.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024944348.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024941790.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024945393.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_024936564.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015596830.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015586460.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-5696397 "Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"DNA replication initiation";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_015591007.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015590037.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_015587970.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_015596110.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101 "MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation" XP_015589970.1 18 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6790901 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol" XP_015600351.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878 "COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport" XP_024945316.1 18 MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6638;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00401+2.6.1.1 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis" XP_015587337.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_015588684.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024935454.1 6 MetaCyc: PWY-5514;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;KEGG: 00520+5.4.2.3 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism" XP_015608526.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015602004.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015596968.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015595953.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015600898.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_015607501.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_024939941.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_015608832.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase" XP_024940741.1 10 Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-111459 "Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage" XP_015598803.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015598936.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_015610177.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024938168.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015600613.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_015584960.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_024946744.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024938439.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015602597.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015588339.1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7176 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis" XP_015592278.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015585473.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_015585645.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_024942597.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_015600404.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015590869.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_015591081.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024947419.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_024939141.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015597189.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_024938536.1 8 Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism" XP_015600361.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024945056.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015609306.1 24 Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Aggrephagy";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024946462.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_024938179.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_024943997.1 6 KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807 "Galactose metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)" XP_015600953.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_024941255.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015586908.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015597577.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_015589359.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024947401.1 42 Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-110330;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-110331 "HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected purine";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"HCMV Late Events";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"Packaging Of Telomere Ends";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"HDACs deacetylate histones";"Meiotic synapsis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine" XP_015588366.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_024943422.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_015592196.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins" XP_015601914.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_024944537.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015585266.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_015605914.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_015601200.1 4 KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_015603214.1 10 Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-3899300 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors" XP_024941589.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_015595181.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_024941576.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015599032.1 5 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_015604982.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024935787.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024945577.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024947827.1 4 MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_015602957.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015607018.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_015587094.1 6 Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16 "Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation" XP_015593083.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_024938403.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_015606971.1 10 Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756 "HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation" XP_015601381.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015584791.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_024940919.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015601994.1 3 KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271 "Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism" XP_024947539.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_015609797.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015598981.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_015596383.1 34 Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-69202;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-8939236;Reactome: R-HSA-69273;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-69656;Reactome: R-HSA-73772;Reactome: R-HSA-69231;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73863 "Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin E associated events during G1/S transition";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin A/B1/B2 associated events during G2/M transition";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination" XP_015607017.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_015590533.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024939125.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_024947826.1 4 MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis" XP_015599331.1 58 Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-5689901;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174178 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Metalloprotease DUBs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_024945441.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015585132.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway" XP_015593274.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015599714.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015600391.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_024945010.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015607669.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-8853884 "Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX" XP_015599737.1 8 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Recycling pathway of L1";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_015607689.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024936657.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015605417.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015596582.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910 "HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs" XP_015601242.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024941604.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_015589786.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_024944589.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015592499.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_024941972.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_024940411.1 16 Reactome: R-HSA-1266695;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-1660499;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-194840 "Interleukin-7 signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Rho GTPase cycle" XP_015590828.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024946570.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015606970.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation" XP_024942164.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_024946158.1 1 Reactome: R-HSA-445355 "Smooth Muscle Contraction" XP_015593359.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_024942842.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015603216.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024935571.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015586117.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_015586681.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_015605765.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_015592586.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024942167.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015586972.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_015589000.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015585904.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_015604810.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015601054.1 8 Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34 "Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis" XP_015586572.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_015600292.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015606999.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_024946643.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015605274.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015600701.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation" XP_024942186.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_015597661.1 13 Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101 "Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"CS/DS degradation" XP_015603229.1 4 KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.9 "Galactose metabolism";"Starch and sucrose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis" XP_015604130.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015601460.1 22 MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-6433;MetaCyc: PWY-7727;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6958;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7053;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7724 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_024944926.1 5 Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_015587782.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015598615.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_015584955.1 5 Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;MetaCyc: PWY-6168;MetaCyc: PWY-5523 "Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)" XP_024937387.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_024936455.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_015609111.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_024936353.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_024946873.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015591264.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015607244.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015602758.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015607162.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015590228.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_015586810.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_015589863.1 6 MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-5651;MetaCyc: PWY-7717 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I" XP_024945680.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015591648.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467;Reactome: R-HSA-2173796 "Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_015602584.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_015594926.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024938057.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015591365.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_015605709.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_015586591.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_015590443.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_015588181.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015586680.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024939644.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015603880.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015591095.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024942272.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_015599112.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024939659.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-1368082 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"Estrogen-dependent gene expression";"Circadian Clock";"RORA activates gene expression" XP_015601132.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024947872.1 2 Reactome: R-HSA-419771;Reactome: R-HSA-8951664 "Opsins";"Neddylation" XP_024947569.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015594704.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015604451.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_015605877.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876 "Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_024939143.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261 "Triglyceride catabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I" XP_024943845.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015588639.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_015608219.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9 "Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_015607922.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_015604538.1 7 Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-69205 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G1/S-Specific Transcription" XP_024946743.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043 "G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events" XP_015604548.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_015596667.1 5 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015602185.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_024947636.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015610470.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_024946855.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_024938654.1 13 MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-7709;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-6383 "All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" XP_024944897.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015603733.1 4 Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-9615017 "AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_024937857.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015596559.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015601555.1 16 Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167290 "Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation" XP_024937327.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015601758.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_024942155.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_024938342.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_015598523.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_015586858.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_015590294.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_015597138.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015589804.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015591748.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_024945036.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024944045.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015590431.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation" XP_024942927.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_024938271.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015609677.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-112043 "Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"PLC beta mediated events" XP_015591720.1 7 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism" XP_015589340.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015608208.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_024937767.1 17 MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2 "Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis";"Pyruvate metabolism";"Jadomycin biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism" XP_015609186.1 14 Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5628897 "Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes" XP_015603499.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015609686.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_015589581.1 5 KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I" XP_015596806.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_015592704.1 16 Reactome: R-HSA-437239;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-164939;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900 "Recycling pathway of L1";"Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"Formation of annular gap junctions";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Nef mediated downregulation of CD28 cell surface expression";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4" XP_015593275.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_024942591.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024935826.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_015608647.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015585226.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_015606017.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024942541.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_024938221.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244 "Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ion homeostasis";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation" XP_015606205.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_015605369.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024936003.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015609171.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024947086.1 7 MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-4302 "NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Complex I biogenesis";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)" XP_024940366.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_015585953.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024937638.1 9 Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_015594145.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015591321.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_024945504.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015591445.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015585080.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_024940776.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015609947.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-110314 "HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex" XP_015603685.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024945380.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_015595991.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015603423.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_015603774.1 7 KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Phytate degradation I";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol" XP_024938598.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_015604395.1 4 Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_024944369.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015587856.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024937336.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_024936503.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024945785.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_024944638.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024942121.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015598728.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015597021.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024945579.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015601194.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015588268.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_015602686.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_015595743.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_024945157.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024941065.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_024947298.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015603551.1 5 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway" XP_015593609.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_024936970.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015607170.1 10 MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-3821 "UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification" XP_015606429.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_015603684.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024937227.1 10 MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11 "Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Methane metabolism" XP_015588223.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_015608363.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_015584912.1 5 KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221 "Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway" XP_015610390.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening" XP_024937693.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN" XP_024935694.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_024937329.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024943452.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_015588610.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015596125.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015597375.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024939723.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_024935949.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015587968.1 5 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA" XP_015598546.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_024936729.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_015586655.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015606852.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_015592612.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015604616.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015592883.1 5 KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006 "Glutathione metabolism";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_024942270.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015598756.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle" XP_015590809.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024938876.1 8 MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109 "Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis" XP_015593725.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_015585349.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024942668.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024943373.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_024943759.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015599927.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024938672.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015586133.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024936084.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_024941397.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1 "G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"Purine metabolism" XP_015592274.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_015586828.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_015609098.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_015598145.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_024941359.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_015602703.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024942715.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024935964.1 6 Reactome: R-HSA-2029485;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1489509;Reactome: R-HSA-1250196;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"DAG and IP3 signaling";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_024947354.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015590854.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_015608627.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015604736.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015586441.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_015591532.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015606039.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015596712.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024945838.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_024947238.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024947577.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015585505.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015588799.1 4 Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193 "Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_015605269.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015607830.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_015607199.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_015593687.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024936435.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "PKA activation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_015604655.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015607169.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_015584712.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_015585989.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_015598041.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;Reactome: R-HSA-1475029 "3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide" XP_015599078.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015602833.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024938359.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_024945957.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024936187.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7587 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_024940068.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_015605462.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024936051.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015598168.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015596763.1 9 Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "GPVI-mediated activation cascade";"NRAGE signals death through JNK";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_015592799.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_015604563.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015601815.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015606253.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024935932.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_024942359.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_015603966.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024938456.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_024942138.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015604414.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_015599583.1 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891 "Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)" XP_015592889.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015586140.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015597508.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_024945650.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015596748.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751 "Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity" XP_015607221.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024942099.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_015598754.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-181430 "Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle" XP_024947359.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024940482.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_024941339.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_024947761.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015594696.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015599466.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-5221030 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA" XP_015589869.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015585985.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024943111.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024941625.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_015587625.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015601722.1 7 MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-7282;Reactome: R-HSA-73817 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_015602536.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" XP_015591423.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015591015.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport" XP_015605444.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_015598210.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015588997.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_015606687.1 11 Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530 "Signaling by ERBB2";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_015607208.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_015609289.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_024946864.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024937916.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015587018.1 16 Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-3214847 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HATs acetylate histones" XP_015607853.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_015603208.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-400206 "NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha" XP_015588190.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_024945818.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024938836.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015594468.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015593714.1 13 Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101 "Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation" XP_015586509.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_024947674.1 6 MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259 "Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Purine catabolism" XP_015593686.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024939575.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015585731.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024947863.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_024936507.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015592912.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015586855.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_024941746.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_015600809.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_015607248.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_024937978.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024946739.1 4 MetaCyc: PWY-8026;Reactome: R-HSA-6807062;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72 "Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis" XP_015588045.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_015604743.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015597703.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024942214.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_015587398.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015605809.1 15 Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176412 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C" XP_015604912.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015597301.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_024944639.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015606854.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_015610537.1 4 Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024937943.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024938877.1 8 MetaCyc: PWY-7979;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_024940050.1 5 Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233 "TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway" XP_015592735.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_015601889.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_015596430.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation" XP_015602287.1 20 MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-6920 "Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)" XP_015587252.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria" XP_015599053.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_024939702.1 16 Reactome: R-HSA-70263;MetaCyc: PWY-7124;MetaCyc: PWY-6886;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1622;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6142 "Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Methane metabolism";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_015600949.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_015592357.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-165054 "Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA" XP_024941655.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015597602.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_015591715.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015597095.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_024947020.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_015604183.1 4 MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906 "N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_015595473.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_015596115.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015597485.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_015609709.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015587350.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015604702.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024937328.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015588850.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_015595588.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015601892.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_024935886.1 9 MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385 "Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)" XP_015585838.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024943926.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015602630.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024944475.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015607437.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015594139.1 5 MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2 "Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis" XP_015604450.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015598009.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015588986.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_024939893.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_024947540.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_024943375.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_024943348.1 4 KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I" XP_024936150.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015608546.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_024937330.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015602357.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015607241.1 1 KEGG: 00051+2.7.1.202 "Fructose and mannose metabolism" XP_015603306.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024943220.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_024946740.1 4 KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026 "Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)" XP_015593080.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015606868.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015587536.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015603921.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_015584729.1 14 Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169 "Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Polymerase switching";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis" XP_024937352.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024935500.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015585098.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015602449.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015601887.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_024938992.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015608861.1 4 Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_015598840.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_015586961.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024947825.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_024943000.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_015598664.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015596718.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015605472.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_015596787.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015601609.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015584997.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" XP_024935506.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_024945847.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_015604870.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015597842.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015610254.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_015595306.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024943505.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015593907.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015586051.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_024940368.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015609896.1 22 Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015606707.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015602094.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_024947087.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-5628897 "Respiratory electron transport";"Complex I biogenesis";"TP53 Regulates Metabolic Genes" XP_015593525.1 7 MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;Reactome: R-HSA-2029485 "Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PG";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis" XP_024945248.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_024945837.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_015586909.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_024937971.1 15 MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-6901 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Glycerol degradation to butanol";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Superpathway of glucose and xylose degradation" XP_024946574.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015599091.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024935665.1 2 Reactome: R-HSA-167827;Reactome: R-HSA-167826 "The proton buffering model";"The fatty acid cycling model" XP_024937773.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015592977.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015585412.1 18 Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955 "RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"mRNA Capping";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation" XP_024944191.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015588475.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation" XP_015605957.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_024945971.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024936638.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174084 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_015605460.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015593905.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_015606014.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_015589225.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024937284.1 7 KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism" XP_015595576.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_015599188.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_024935668.1 4 KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis" XP_015592899.1 16 MetaCyc: PWY-1622;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-6886;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-2221 "Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_015599881.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015610379.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_015600194.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_015603113.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024947774.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015609639.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024944917.1 29 Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-6804760;Reactome: R-HSA-5693579;Reactome: R-HSA-69541;Reactome: R-HSA-5693565;Reactome: R-HSA-6803207;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685942;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-6803204;Reactome: R-HSA-349425;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"PI3K-Akt signaling pathway";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Methylation";"Homologous DNA Pairing and Strand Exchange";"Stabilization of p53";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Degradation";"Thermogenesis";"HDR through Homologous Recombination (HRR)";"Human papillomavirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Autodegradation of the E3 ubiquitin ligase COP1";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection" XP_024941251.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015607367.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015596341.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015586902.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015608888.1 6 KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11 "Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_024945848.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_015588772.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015592758.1 10 MetaCyc: PWY-5892;MetaCyc: PWY-7996;MetaCyc: PWY-5890;Reactome: R-HSA-2142789;MetaCyc: PWY-5849;MetaCyc: PWY-5891;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163 "Menaquinol-12 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-10 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_015591479.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_015604737.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015607222.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_024938095.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015594514.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_015603959.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015593267.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_024946043.1 14 Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_015594993.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024945591.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024937828.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024944173.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015590482.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_015590211.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024943642.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024945535.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024935957.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_015605275.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024945435.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation";"Transferrin endocytosis and recycling" XP_015602051.1 2 Reactome: R-HSA-5687128;KEGG: 04150+2.7.11.24 "MAPK6/MAPK4 signaling";"mTOR signaling pathway" XP_015609128.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015586917.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-5578749 "snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs" XP_015589468.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy" XP_024946699.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_015602769.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_015595203.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015602099.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024941969.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_015593394.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry" XP_015590568.1 7 MetaCyc: PWY-7295;MetaCyc: PWY-6969;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-7854;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294 "L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Pyruvate metabolism";"D-xylose degradation IV" XP_024941018.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_024941970.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_024946451.1 4 Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247 "Peroxisomal protein import";"beta-Alanine metabolism";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids" XP_015586316.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" XP_015589969.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_015586691.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_024935503.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_024945878.1 15 Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176407 "Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_024947184.1 6 KEGG: 00250+6.3.4.4;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00030+2.7.6.1 "Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pentose phosphate pathway" XP_024937045.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024946986.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015591848.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_015604543.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024944911.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_015595629.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_024943557.1 16 Reactome: R-HSA-975871;Reactome: R-HSA-975155;Reactome: R-HSA-3134963;Reactome: R-HSA-209543;Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-975138;Reactome: R-HSA-5602680;Reactome: R-HSA-9020702;Reactome: R-HSA-1810476;Reactome: R-HSA-1257604;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-1236974 "MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"p75NTR recruits signalling complexes";"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR5)";"Interleukin-1 signaling";"RIP-mediated NFkB activation via ZBP1";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway" XP_024947651.1 13 Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-4086398 "VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway" XP_015589568.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015603380.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024944175.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015608461.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_024942260.1 11 Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "MHC class II antigen presentation";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_015610388.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_024937678.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription" XP_024941587.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_015593539.1 29 Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-75955 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation" XP_024947578.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015587261.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_024937905.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_015607746.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015589870.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_024939168.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015586793.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015588654.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015599604.1 9 MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-5663 "Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I" XP_015592386.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015598373.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015609290.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_015594544.1 11 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway" XP_024944989.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_024944622.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015592925.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024946401.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate" XP_024940076.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015597576.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024938436.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024941933.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015608309.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015606911.1 7 Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-983168 "Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024944233.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015597075.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024941021.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_015596715.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024935818.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_015602964.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_015605850.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015594371.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015602427.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015603531.1 5 Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668 "Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_024936574.1 3 MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation" XP_024937486.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_015607914.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_024940918.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015592614.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_015585515.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024936364.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_024945562.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015585829.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024947790.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015589602.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892 "HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation" XP_024943658.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015600845.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024946465.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_015603776.1 7 MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363 "Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_015609694.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_015588316.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015587349.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015589424.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_015602197.1 17 Reactome: R-HSA-9022692;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-174178;Reactome: R-HSA-9648025;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Regulation of MECP2 expression and activity";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"EML4 and NUDC in mitotic spindle formation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_015587668.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_015592314.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_015589874.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015597729.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_015596887.1 8 Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-5099900 "Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4" XP_015601811.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531 "Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus" XP_015598984.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_015585868.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_015586358.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_015596978.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_015587726.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910 "HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs" XP_015604212.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024941471.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169 "Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis" XP_015587453.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_024944991.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" XP_015608653.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_024940418.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_015603680.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024941914.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024935679.1 6 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis" XP_015587173.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_015587496.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_015607863.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6598 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis" XP_015586682.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_024937272.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148 "RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015596294.1 10 Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-917729 "Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Inhibition of membrane repair";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_015610179.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015598288.2 8 KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27 "Pyruvate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis" XP_024942922.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_024943103.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024946161.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015585075.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024942238.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015604889.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_015605149.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015592789.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_015593723.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_024943164.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_024937962.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152 "RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat" XP_015600758.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015595409.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_015593329.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994 "ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_015604956.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_015601241.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_024940764.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024938425.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_024946110.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_015605398.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs" XP_024943129.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_015594725.1 11 Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-72163;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-210744 "Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_015603866.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_024943664.1 13 MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_015599662.1 6 Reactome: R-HSA-5609978;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370 "Defective GALT can cause Galactosemia";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism" XP_015596645.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" YP_002889390.1 7 Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083;MetaCyc: PWY-4302 "Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Complex I biogenesis";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration III (alternative oxidase pathway)" XP_024939635.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024939322.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024935968.1 5 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway" XP_024947864.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_015590783.1 11 Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1632852;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;Reactome: R-HSA-109704;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Macroautophagy";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases" XP_024936704.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_015595437.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015595000.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024941650.1 5 Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007 "VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"mTOR signaling pathway";"p38MAPK events" XP_024937958.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024940865.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN" XP_015591297.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015598773.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024938458.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_015596888.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_015601544.1 179 Reactome: R-HSA-5693565;Reactome: R-HSA-3785653;Reactome: R-HSA-1295596;Reactome: R-HSA-5655862;Reactome: R-HSA-175474;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-3322077;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5685942;Reactome: R-HSA-9633012;Reactome: R-HSA-5357905;Reactome: R-HSA-5684264;Reactome: R-HSA-211733;Reactome: R-HSA-5675482;Reactome: R-HSA-205043;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-110312;Reactome: R-HSA-2173791;Reactome: R-HSA-8866654;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-6781823;Reactome: R-HSA-936964;Reactome: R-HSA-5610780;Reactome: R-HSA-9645460;Reactome: R-HSA-174048;Reactome: R-HSA-5607764;Reactome: R-HSA-901032;Reactome: R-HSA-9014325;Reactome: R-HSA-5675221;Reactome: R-HSA-912631;Reactome: R-HSA-5696400;Reactome: R-HSA-3769402;Reactome: R-HSA-1169091;Reactome: R-HSA-975144;Reactome: R-HSA-2644606;Reactome: R-HSA-917937;Reactome: R-HSA-5689877;Reactome: R-HSA-8866652;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-937041;Reactome: R-HSA-180534;Reactome: R-HSA-2672351;Reactome: R-HSA-975956;Reactome: R-HSA-8948747;Reactome: R-HSA-1253288;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-5654733;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-69541;Reactome: R-HSA-9010553;Reactome: R-HSA-162588;Reactome: R-HSA-2408557;Reactome: R-HSA-174154;Reactome: R-HSA-8876493;Reactome: R-HSA-8939902;Reactome: R-HSA-2122947;Reactome: R-HSA-9646399;Reactome: R-HSA-156827;Reactome: R-HSA-174084;Reactome: R-HSA-937039;Reactome: R-HSA-8849469;Reactome: R-HSA-5668541;Reactome: R-HSA-5656169;Reactome: R-HSA-977225;Reactome: R-HSA-168638;Reactome: R-HSA-382556;Reactome: R-HSA-6804757;Reactome: R-HSA-937072;Reactome: R-HSA-2559582;Reactome: R-HSA-6804760;Reactome: R-HSA-6783310;Reactome: R-HSA-983168;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-5696394;Reactome: R-HSA-5656121;Reactome: R-HSA-9613829;Reactome: R-HSA-5689901;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-8948751;Reactome: R-HSA-9637628;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2559585;Reactome: R-HSA-2871837;Reactome: R-HSA-5654726;Reactome: R-HSA-532668;Reactome: R-HSA-72706;Reactome: R-HSA-5658442;Reactome: R-HSA-5693607;Reactome: R-HSA-1236382;Reactome: R-HSA-9615710;Reactome: R-HSA-174178;Reactome: R-HSA-2691232;Reactome: R-HSA-69017;Reactome: R-HSA-1358803;Reactome: R-HSA-6782210;Reactome: R-HSA-2122948;Reactome: R-HSA-975957;Reactome: R-HSA-2979096;Reactome: R-HSA-4641258;Reactome: R-HSA-72764;Reactome: R-HSA-450408;Reactome: R-HSA-2173796;Reactome: R-HSA-168927;Reactome: R-HSA-5654732;Reactome: R-HSA-5696395;Reactome: R-HSA-8863795;Reactome: R-HSA-1169408;Reactome: R-HSA-8852276;Reactome: R-HSA-2559580;Reactome: R-HSA-9033241;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9636383;Reactome: R-HSA-9013507;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-8856825;Reactome: R-HSA-5689896;Reactome: R-HSA-110320;Reactome: R-HSA-8854050;Reactome: R-HSA-174490;Reactome: R-HSA-5654727;Reactome: R-HSA-3134975;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-4641263;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-2894862;Reactome: R-HSA-69231;Reactome: R-HSA-6781827;Reactome: R-HSA-445989;Reactome: R-HSA-8951664;Reactome: R-HSA-209560;Reactome: R-HSA-2173795;Reactome: R-HSA-5362768;Reactome: R-HSA-9013973;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788;Reactome: R-HSA-8941858;Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-174184;Reactome: R-HSA-937042;Reactome: R-HSA-975110;Reactome: R-HSA-168928;Reactome: R-HSA-8856828;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-201681;Reactome: R-HSA-6804756;Reactome: R-HSA-156902;Reactome: R-HSA-450302;Reactome: R-HSA-5689603;Reactome: R-HSA-179409;Reactome: R-HSA-180585;Reactome: R-HSA-936440;Reactome: R-HSA-174113;Reactome: R-HSA-4641257 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myoclonic epilepsy of Lafora";"Spry regulation of FGF signaling";"Translesion synthesis by POLK";"Assembly Of The HIV Virion";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Glycogen synthesis";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"HDR through Homologous Recombination (HRR)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of TNFR1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of necroptotic cell death";"NRIF signals cell death from the nucleus";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Translesion synthesis by REV1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"E3 ubiquitin ligases ubiquitinate target proteins";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Formation of TC-NER Pre-Incision Complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Degradation of GLI1 by the proteasome";"Alpha-protein kinase 1 signaling pathway";"APC/C:Cdc20 mediated degradation of Cyclin B";"CLEC7A (Dectin-1) signaling";"ER Quality Control Compartment (ERQC)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Negative regulation of MAPK pathway";"Regulation of signaling by CBL";"Dual Incision in GG-NER";"Deactivation of the beta-catenin transactivating complex";"Activation of NF-kappaB in B cells";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Iron uptake and transport";"Josephin domain DUBs";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"IKK complex recruitment mediated by RIP1";"Vpu mediated degradation of CD4";"Stimuli-sensing channels";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of PTEN localization";"Downregulation of ERBB4 signaling";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of FGFR4 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Stabilization of p53";"Regulation of expression of SLITs and ROBOs";"Budding and maturation of HIV virion";"Selenocysteine synthesis";"APC/C:Cdc20 mediated degradation of Securin";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of RUNX2 expression and activity";"NOTCH1 Intracellular Domain Regulates Transcription";"Aggrephagy";"L13a-mediated translational silencing of Ceruloplasmin expression";"Autodegradation of Cdh1 by Cdh1:APC/C";"IRAK1 recruits IKK complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"TNFR2 non-canonical NF-kB pathway";"Termination of translesion DNA synthesis";"Amyloid fiber formation";"NOD1/2 Signaling Pathway";"ABC-family proteins mediated transport";"Regulation of TP53 Degradation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of TP53 Activity through Methylation";"Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"DNA Damage Recognition in GG-NER";"Translesion synthesis by POLI";"Chaperone Mediated Autophagy";"Metalloprotease DUBs";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"Regulation of PTEN stability and activity";"Modulation by Mtb of host immune system";"Dual incision in TC-NER";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Oncogene Induced Senescence";"FCERI mediated NF-kB activation";"Negative regulation of FGFR1 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of RAS by GAPs";"Processing of DNA double-strand break ends";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Late endosomal microautophagy";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of ERBB2:ERBB3 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of DVL";"Eukaryotic Translation Termination";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TICAM1, RIP1-mediated IKK complex recruitment";"Negative regulation of FGFR3 signaling";"Formation of Incision Complex in GG-NER";"Downregulation of ERBB2 signaling";"ISG15 antiviral mechanism";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxidative Stress Induced Senescence";"Peroxisomal protein import";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Prevention of phagosomal-lysosomal fusion";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cargo recognition for clathrin-mediated endocytosis";"Ovarian tumor domain proteases";"Translesion Synthesis by POLH";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Membrane binding and targetting of GAG proteins";"Negative regulation of FGFR2 signaling";"Regulation of innate immune responses to cytosolic DNA";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of FZD by ubiquitination";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Cyclin D associated events in G1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Neddylation";"NF-kB is activated and signals survival";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TICAM1-dependent activation of IRF3/IRF7";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX3 expression and activity";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"IRAK2 mediated activation of TAK1 complex";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Clathrin-mediated endocytosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TCF dependent signaling in response to WNT";"Regulation of TP53 Activity through Phosphorylation";"Peptide chain elongation";"activated TAK1 mediates p38 MAPK activation";"UCH proteinases";"APC-Cdc20 mediated degradation of Nek2A";"Vif-mediated degradation of APOBEC3G";"Negative regulators of DDX58/IFIH1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN" XP_024946760.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015586464.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_015594453.1 17 Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-112382;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-674695 "HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Th1 and Th2 cell differentiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events" XP_015600010.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_015603980.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024936383.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015604825.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015594763.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015585496.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024936716.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015599602.1 9 Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-6147;MetaCyc: PWY-7442;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-6703 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis" XP_024935502.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_024947869.1 2 Reactome: R-HSA-419771;Reactome: R-HSA-8951664 "Opsins";"Neddylation" XP_024944349.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024936301.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015592839.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_024935977.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_024943433.1 13 Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-167590 "Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"LDL clearance";"Recycling pathway of L1";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation" XP_015586223.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024941616.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_015596762.1 9 Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "Rho GTPase cycle";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_024936319.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026 "VLDL assembly";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"VLDL clearance";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"LDL remodeling";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Chylomicron clearance" XP_015596656.1 33 Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-69656;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-69231;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-69273;Reactome: R-HSA-167162;Reactome: R-HSA-69202;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167200 "Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Cyclin D associated events in G1";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II HIV Promoter Escape";"Cyclin E associated events during G1/S transition";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_015603146.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_015589419.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_015603196.1 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" XP_015607867.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_024938942.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_024946593.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015608078.1 4 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782861 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)" XP_015609719.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_015600466.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_024935553.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_024942773.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015602232.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_015610203.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_015606419.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024944297.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_024935933.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015590194.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015597915.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015600461.1 19 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Chylomicron remodeling";"Chylomicron clearance";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"LDL remodeling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"VLDL assembly";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class A Receptors" XP_015607203.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_015592654.1 56 Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8948751 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity" XP_024942206.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015588364.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_015600375.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_015602755.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015600478.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015609415.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024936691.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_024942736.1 4 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69205 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"G1/S-Specific Transcription" XP_024944207.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_015599640.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015595270.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_015594820.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015595356.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015595319.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015584695.1 9 MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-7411;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902 "CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis" XP_024944046.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024946997.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015601250.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015593849.1 18 MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7221 "UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis" XP_015608080.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_015599681.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_015609583.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_024940497.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015608721.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_024941219.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015608614.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024941118.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024947828.1 4 MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis" XP_015585834.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015605844.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_024936091.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_015601986.1 3 KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999 "Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle" XP_015587117.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015594326.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015592283.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015594045.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_024937304.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015587394.1 15 Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884 "Ca2+ pathway";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX" XP_015593886.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_015597806.1 10 MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8055 "Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis" XP_015599242.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "Estrogen-dependent gene expression";"Circadian Clock";"RMTs methylate histone arginines";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" XP_015594024.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015590026.1 7 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_015607028.1 5 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015595780.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_015606406.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_024936268.1 11 Reactome: R-HSA-2029485;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052 "Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis" XP_015602236.1 9 Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-5649702;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9656255;Reactome: R-HSA-9657050 "Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Binding";"Defective OGG1 Localization" XP_015594327.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024939579.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015600897.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015608357.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)" XP_024942494.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_024939305.1 25 Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-380270;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-9619483 "EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Kinesins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Recruitment of mitotic centrosome proteins and complexes";"Gap junction assembly";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs" XP_015587836.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_015585501.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024944296.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015601413.1 3 Reactome: R-HSA-8939236;Reactome: R-HSA-383280;Reactome: R-HSA-983231 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_024937525.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_015599411.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015593537.1 29 Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-167246 "NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript" XP_015603159.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024935498.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024942202.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015597707.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1" XP_015593641.1 8 MetaCyc: PWY-7817;MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 04658+3.1.3.16;Reactome: R-HSA-1483148;KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Th1 and Th2 cell differentiation";"Synthesis of PG";"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_015600488.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015587813.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_024939594.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_015604893.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015598655.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015587338.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_015597038.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_024947329.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015590960.1 6 MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism" XP_015605156.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_015596899.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015603217.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024936727.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_015605445.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_015597724.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_015589075.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_024937884.1 3 Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807 "Interleukin-20 family signaling";"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling" XP_015588456.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015601367.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_024941006.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015606627.1 30 Reactome: R-HSA-8876198;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-111447;Reactome: R-HSA-392451;Reactome: R-HSA-198693;Reactome: R-HSA-6804759;Reactome: R-HSA-8941332;Reactome: R-HSA-211163;Reactome: R-HSA-199418;Reactome: R-HSA-389513;Reactome: R-HSA-69656;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-198323;Reactome: R-HSA-1358803;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-8948751;Reactome: R-HSA-1257604;Reactome: R-HSA-9634638;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1 "RAB GEFs exchange GTP for GDP on RABs";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"Human papillomavirus infection";"Regulation of TP53 Activity through Acetylation";"Regulation of TP53 Degradation";"Thermogenesis";"Activation of BAD and translocation to mitochondria";"G beta:gamma signalling through PI3Kgamma";"AKT phosphorylates targets in the nucleus";"Regulation of TP53 Activity through Association with Co-factors";"RUNX2 regulates genes involved in cell migration";"AKT-mediated inactivation of FOXO1A";"Negative regulation of the PI3K/AKT network";"CTLA4 inhibitory signaling";"Cyclin A:Cdk2-associated events at S phase entry";"Relaxin signaling pathway";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the cytosol";"Downregulation of ERBB2:ERBB3 signaling";"Human cytomegalovirus infection";"Cyclin E associated events during G1/S transition";"Regulation of PTEN stability and activity";"PIP3 activates AKT signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway" XP_015591727.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015607972.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015604827.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015595490.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015605606.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_015597414.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024938845.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015602796.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_024945780.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_024939668.1 9 Reactome: R-HSA-5674400;Reactome: R-HSA-168638;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-418889;Reactome: R-HSA-198323;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111464 "Constitutive Signaling by AKT1 E17K in Cancer";"NOD1/2 Signaling Pathway";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Caspase activation via Dependence Receptors in the absence of ligand";"AKT phosphorylates targets in the cytosol";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_024936885.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_015594611.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_024939711.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015604788.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015603199.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015600682.1 3 Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_015596619.1 3 KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_024943654.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015595817.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_015603338.1 1 MetaCyc: PWY-6938 "NADH repair" XP_015597871.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8953750 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6" XP_024936157.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015597685.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015591683.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024938900.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015594391.1 57 Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556 "CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport" XP_015586598.1 9 Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-381340 "Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation" XP_024946166.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_024941062.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015598706.1 13 MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7198 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_015586143.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024947655.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809 "CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization" XP_024936137.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015605779.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015592768.1 14 Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852 "MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Macroautophagy" XP_015585676.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024941528.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024935801.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_015609465.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015602380.1 13 Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178 "Integrin cell surface interactions";"Collagen chain trimerization";"Collagen degradation";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"Laminin interactions";"Extracellular matrix organization";"NCAM1 interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans" XP_015593358.1 9 Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_015605201.1 10 KEGG: 05165+2.7.1.153;KEGG: 04150+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05163+2.7.1.153;KEGG: 04151+2.7.1.153 "Human papillomavirus infection";"mTOR signaling pathway";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_024936288.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015604131.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015585809.1 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"NRAGE signals death through JNK";"Relaxin signaling pathway";"G alpha (q) signalling events";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_015604464.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_024944512.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024942236.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015608568.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015584929.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015609642.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015585774.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024936088.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015585803.1 12 Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Rho GTPase cycle";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_024942136.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015606187.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_015585516.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015606754.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015585207.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_024942028.1 5 MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317 "Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)" XP_015584966.1 8 Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Telomere C-strand synthesis initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"DNA replication initiation";"Removal of the Flap Intermediate" XP_015584844.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_015609646.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-9627069 "Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity" XP_024936180.1 10 MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8053 "Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II" XP_024939973.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_024938228.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324 "Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_024944411.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015607607.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015596538.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_024941860.1 10 Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292 "Neutrophil degranulation";"Galactose metabolism";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"MPS VII - Sly syndrome" XP_015606023.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_024942468.1 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1 "Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism" XP_024937192.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_015585830.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015586860.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015602750.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024939883.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015601858.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015602711.2 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_024941919.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_024938151.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015587340.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_015604265.1 18 MetaCyc: PWY-5913;MetaCyc: PWY-6638;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00270+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00400+2.6.1.1 "Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_024941578.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024938054.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024937769.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015587595.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_015588296.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_015608838.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015600252.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015587359.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_015610195.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015584817.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015590331.1 15 MetaCyc: PWY-7003;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40 "Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism" XP_024935673.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024938859.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_024945682.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015604970.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_015590039.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_024936533.1 7 Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;MetaCyc: PWY-5188 "Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)" XP_024939573.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015600501.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024946464.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_015594377.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015606957.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015586135.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015593482.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_024938157.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_024942240.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_015589328.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015599167.1 12 MetaCyc: PWY-6842;MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-1187;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936 "Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)" XP_024938880.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_015605818.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_015606410.1 1 Reactome: R-HSA-445355 "Smooth Muscle Contraction" XP_015599565.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015585267.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_015605068.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_015598353.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015602523.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_015598275.2 9 KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842 "Glutathione metabolism";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II" XP_015584694.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_024945426.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015605879.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_015585664.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024945894.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_024947759.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015605080.1 7 Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-180746 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein" XP_024944204.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024938669.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015592898.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024944371.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015609823.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" XP_024936138.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015603734.1 4 Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-198693 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus" XP_024938807.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024946292.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_024936246.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015603773.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015591723.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015585379.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024942027.1 5 MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6 "D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism" XP_015603906.1 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_015610030.1 4 Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399 "Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Aggrephagy" XP_024938873.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015599410.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015591461.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_015586688.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015586697.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_024940689.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015601332.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015600380.1 17 Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-1834949 "Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Cytosolic sensors of pathogen-associated DNA" XP_015595521.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015595788.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024935501.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024947433.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_015585948.1 12 Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-73980 "Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination" XP_024941984.1 3 Reactome: R-HSA-5694530;Reactome: R-HSA-948021;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport" XP_015605738.1 3 Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627 "O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6" XP_015589190.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_024938096.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015588929.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_024942134.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024945801.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015591170.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_024941338.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_024943048.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015599885.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015593142.1 18 Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-1482788 "Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Anandamide biosynthesis I";"Acyl chain remodelling of PC" XP_024936905.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_015610473.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_015604539.1 7 Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest" XP_015602023.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_015594577.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015597711.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015584688.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029 "3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide" XP_015585812.1 12 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway" XP_024941766.1 12 KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6613;Reactome: R-HSA-196780;KEGG: 00970+2.1.2.9;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;MetaCyc: PWY-6277 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Biotin transport and metabolism";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_015586760.1 14 MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411 "Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)" XP_015605052.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_024942414.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024947280.1 3 MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590 "Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation" XP_015597882.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015600731.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_015586784.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024942305.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_015591728.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024943116.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024942213.1 3 KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1 "Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway" XP_024943493.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_024947423.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024945651.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015587463.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015607572.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-674695 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events" XP_015591492.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_015586599.1 14 Reactome: R-HSA-9634638;Reactome: R-HSA-69273;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-5663220;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-9648025 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"RHO GTPases Activate Formins";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation" XP_024940066.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_024941215.1 15 Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944 "Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2" XP_015597697.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" XP_024947541.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024941944.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015601481.1 5 KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7159;MetaCyc: PWY-7766 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)" XP_015601146.1 4 Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_024942378.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024945959.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015592369.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015592833.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015610294.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_024935974.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015591422.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024938452.1 11 KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015609817.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024937592.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024936126.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_015600830.1 32 Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-168325;Reactome: R-HSA-9018519;Reactome: R-HSA-73779 "Formation of the Early Elongation Complex";"mRNA Capping";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Viral Messenger RNA Synthesis";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_015584856.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024943731.1 3 Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144 "Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_015591320.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_015609303.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015603152.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024938728.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015608056.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015586663.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024935785.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015591161.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024943920.1 5 MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis" XP_015597478.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394 "UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER" XP_024938451.1 11 KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection" XP_024943491.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_015590142.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_015600632.1 12 MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-6978;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5873 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)" XP_015608492.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024944865.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism" XP_015594005.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"Hedgehog 'off' state" XP_024941410.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015602631.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015595688.1 4 KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030 "Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_015604184.1 4 Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59 "Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_024941463.1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" XP_024941909.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015591179.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-71240 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane";"Tryptophan catabolism" XP_024942449.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015586766.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_024941789.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015607650.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_015601282.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_015599070.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015585380.1 6 MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol" XP_015588644.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_015604728.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_015607459.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_024939145.1 6 MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952 "Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation" XP_015605180.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015588502.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_015595086.1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_015604439.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression" XP_015606329.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024941938.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015602358.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015602768.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_015596579.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_015587789.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_024937030.1 10 MetaCyc: PWY-6365;Reactome: R-HSA-983231;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6366;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855204;MetaCyc: PWY-6362 "D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_015590936.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_024946854.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024947351.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015604362.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_015595223.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_024936186.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7587 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_015604115.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015599756.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_024941905.1 4 Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16 "Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_015597507.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_015597520.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_015593491.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024939540.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015597680.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" XP_024941988.1 7 Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-9018676;Reactome: R-HSA-9018896;Reactome: R-HSA-6798695;Reactome: R-HSA-9023661;Reactome: R-HSA-9020265 "Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Neutrophil degranulation";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins" XP_015594616.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015600159.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway" XP_024941702.1 57 Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-8939902 "Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity" XP_024937362.1 5 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_015589014.1 19 Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-202733 "Chylomicron remodeling";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Chylomicron clearance";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"LDL remodeling";"VLDL assembly";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"VLDL clearance";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall" XP_015585513.1 2 MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_024942076.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15 "Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_024944293.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_015605079.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015603043.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015594662.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024945631.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_015596801.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024940413.1 16 Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-388841;Reactome: R-HSA-1266695;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-389357 "Regulation of signaling by CBL";"GPVI-mediated activation cascade";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"Costimulation by the CD28 family";"Interleukin-7 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling" XP_015603268.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024944199.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_024940711.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_015585903.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_015591735.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_015586172.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_015590012.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015607276.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015598782.1 13 Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-2871837 "TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation" XP_024947241.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024944340.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015597553.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6798695 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"Neutrophil degranulation" XP_024946992.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015607841.1 18 KEGG: 00280+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-5362517;MetaCyc: PWY-5084;Reactome: R-HSA-71064;KEGG: 00260+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00380+1.8.1.4;KEGG: 00020+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00620+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-71403;Reactome: R-HSA-70895;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4;MetaCyc: PWY-5046 "Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Signaling by Retinoic Acid";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Glycine, serine and threonine metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glycine degradation";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Branched-chain amino acid catabolism";"Lysine degradation";"Glycolysis / Gluconeogenesis";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA" XP_015594787.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024944486.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_015607604.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015598144.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_015593708.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015606639.1 4 Reactome: R-HSA-196791;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8856825 "Vitamin D (calciferol) metabolism";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis" XP_024941636.1 18 KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417 "Ether lipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Synthesis of PA";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)" XP_024941398.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787 "Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Hedgehog 'off' state" XP_024946960.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015602617.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex" XP_024947830.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189 "Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)" XP_015586002.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015597860.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_015584728.1 14 Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-69091 "Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Polymerase switching" XP_024945950.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015590613.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_015599898.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5362798 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell" XP_015603342.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015596394.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_015607831.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_024935831.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024941403.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_024937947.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015600895.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024945962.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015584788.1 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" XP_024943432.1 3 KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis" XP_015606111.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_024944863.1 5 KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Galactose metabolism" XP_015606461.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_024942595.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_015604559.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015610333.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015601759.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_024947337.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024943941.1 20 MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7205;Reactome: R-HSA-380320;KEGG: 00983+2.7.4.6;Reactome: R-HSA-380270;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222 "Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Recruitment of NuMA to mitotic centrosomes";"Drug metabolism - other enzymes";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_015592127.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024937197.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024940348.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015598167.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015609506.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015592685.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_024943354.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_015597134.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024936005.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024941939.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024947724.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_024946839.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8853884 "Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX" XP_024943858.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024943167.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_024945555.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015603875.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_024935786.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015609641.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024944232.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015597062.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024942404.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_024947228.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015595818.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024939744.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024946277.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015608491.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024937724.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation" XP_024943733.1 7 KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;MetaCyc: PWY-6471;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15 "Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis" XP_024940818.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015600101.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015598671.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024946893.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_024943787.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_024936502.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015593367.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate" XP_024946932.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_024943507.1 15 Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607 "Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends" XP_024942094.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_024936235.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_015606542.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024939875.1 18 Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482922 "Synthesis of PA";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PI" XP_015600486.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_015597834.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015586153.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_024945467.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015607424.1 42 Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847 "Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Amyloid fiber formation";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Meiotic synapsis";"HDACs deacetylate histones";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"HATs acetylate histones" XP_024943655.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_015595328.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN" XP_015607522.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015591721.1 7 KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16 "Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism" XP_015607928.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024941191.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_024938148.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024940376.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_015602435.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015588431.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919 "Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils" XP_015606432.2 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_024945783.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_015589079.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_024935823.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015591268.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015597575.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015590966.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024939386.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015598435.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015605076.1 4 KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975 "Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate" XP_015586319.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_024936495.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024939824.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_024943504.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015588192.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_024939328.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_015594646.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_015591332.1 13 Reactome: R-HSA-2871796;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;MetaCyc: PWY-6367;Reactome: R-HSA-2029485;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277 "FCERI mediated MAPK activation";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"D-myo-inositol-5-phosphate metabolism";"Role of phospholipids in phagocytosis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)" XP_015600900.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015591074.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024940194.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024938223.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-877300 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling" XP_015586824.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_015591726.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015602264.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015610426.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_024943236.1 4 KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" XP_015593859.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399 "Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_015600803.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015593768.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis" XP_015609557.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024936375.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015598452.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015592387.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024947424.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_024942380.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_015593139.1 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_024937286.1 7 Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500 "TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle" XP_015590636.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015607161.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024940109.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024935465.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_024943966.1 11 Reactome: R-HSA-391160;Reactome: R-HSA-912694;Reactome: R-HSA-9008059;Reactome: R-HSA-114604;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-389948;Reactome: R-HSA-388841;Reactome: R-HSA-877312;Reactome: R-HSA-432142;Reactome: R-HSA-210990 "Signal regulatory protein family interactions";"Regulation of IFNA signaling";"Interleukin-37 signaling";"GPVI-mediated activation cascade";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PD-1 signaling";"Costimulation by the CD28 family";"Regulation of IFNG signaling";"Platelet sensitization by LDL";"PECAM1 interactions" XP_024936807.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_024940272.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024945392.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_024942283.1 8 MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5739;KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;Reactome: R-HSA-6787639;MetaCyc: PWY-5740 "GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis" XP_015584931.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_015592290.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_015587312.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015586136.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024938324.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024944881.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024941924.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024938939.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_024940120.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_015590364.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-2660826;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-177929 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TNF signaling";"Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Signaling by EGFR" XP_024947239.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015607637.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015598780.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_024939892.1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897 "Regulation of PTEN gene transcription";"Neutrophil degranulation";"mTOR signalling";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes" XP_024942647.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_015585252.1 6 Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_015596207.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015586668.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015587401.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;MetaCyc: PWY-7511 "Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Protein ubiquitination" XP_024940962.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_015596908.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24 "FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway" XP_024939630.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015604837.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_015599643.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015584684.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_024944114.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_015607744.1 4 Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-186763 "Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Downstream signal transduction" XP_024937807.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015592356.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746 "Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein" XP_015590990.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015587255.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015603897.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024937973.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024936486.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015602455.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-165054 "HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA" XP_015585728.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015594430.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015599648.1 30 Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-2564830;Reactome: R-HSA-73779 "RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_024945859.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_015609674.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809 "CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization" XP_015604929.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015607553.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024945233.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_024938980.1 11 KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;Reactome: R-HSA-5668599;Reactome: R-HSA-1660499;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1632852;Reactome: R-HSA-168138;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-109704 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Macroautophagy";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"PI3K Cascade" XP_015608523.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_024942056.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015597328.1 12 KEGG: 00670+2.1.2.9;Reactome: R-HSA-196780;MetaCyc: PWY-6613;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.3.1 "One carbon pool by folate";"Biotin transport and metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism" XP_015606756.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_024941658.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015587515.1 11 Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332 "HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_024942825.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_024942772.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015594540.1 11 Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580 "VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"p38MAPK events";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Oxidative Stress Induced Senescence" XP_015597521.1 10 MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13 "Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione metabolism" XP_015609261.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015595256.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015597327.1 12 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6613;Reactome: R-HSA-196780;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.3.1;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"One carbon pool by folate";"Purine metabolism" XP_015585376.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015602077.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_015599882.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015608724.1 42 Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-73772;Reactome: R-HSA-427389;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847 "Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HCMV Late Events";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Amyloid fiber formation";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Meiotic synapsis";"HDACs deacetylate histones";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"HATs acetylate histones" XP_015607685.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015600700.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis" XP_024944187.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_015601068.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015609744.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_015607920.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_015595168.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015592890.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015591330.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015597791.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_015602195.1 17 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-174178;Reactome: R-HSA-9022692;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"EML4 and NUDC in mitotic spindle formation";"Human cytomegalovirus infection";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of MECP2 expression and activity";"Mitotic Prometaphase" XP_024942361.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_024936867.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015599148.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024936453.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_015605349.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015587355.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015601982.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_015609473.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_024940320.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024946363.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015591276.1 57 Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-8939902 "Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity" XP_015609581.1 6 MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259 "Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Purine catabolism" XP_015606860.1 56 Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5668541 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway" XP_015607858.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015588635.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_015584700.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_024941660.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015587700.1 17 KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;KEGG: 00760+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-5532;MetaCyc: PWY-6627;Reactome: R-HSA-74217;MetaCyc: PWY-6644;Reactome: R-HSA-74259;MetaCyc: PWY-7179;MetaCyc: PWY-6620 "Pyrimidine metabolism";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage" XP_015605378.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015589523.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination" XP_015585119.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015596735.1 7 Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381033 "IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones" XP_015585361.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024938906.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015606824.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015593848.1 18 MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;Reactome: R-HSA-499943 "Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates" XP_024945126.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015593138.1 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_024936510.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015592471.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation" XP_024935896.1 5 KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation" XP_024945753.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_015595408.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_015589463.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation" XP_024947137.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_024941321.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015605273.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015586009.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_024942365.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_015599479.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_015594523.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_015609170.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015603678.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015601051.1 8 Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34 "Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis" XP_015587279.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015586081.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_024940207.1 5 MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273 "Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" XP_015599567.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015606251.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024938896.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692 "HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"PPARA activates gene expression";"Regulation of MECP2 expression and activity" XP_024940410.1 15 Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-6811558;Reactome: R-HSA-1660499;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-1266695;Reactome: R-HSA-389357;Reactome: R-HSA-1433557 "GPVI-mediated activation cascade";"Regulation of signaling by CBL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Synthesis of PIPs at the plasma membrane";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"Interleukin-7 signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT" XP_024944193.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015589466.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation" XP_024938599.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_015605449.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024947352.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024946215.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_024943306.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_015598755.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle" XP_015598987.1 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_015610521.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015586414.1 7 MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-7818;MetaCyc: PWY-3385;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82 "Plasmalogen biosynthesis";"Synthesis of PC";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism" XP_024945165.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015607024.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_024940915.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015585084.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_015592798.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_024944298.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_015610523.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_024941008.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015598011.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024940415.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_024940356.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_015607396.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_024945911.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_024941678.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_015594409.1 16 Reactome: R-HSA-1266695;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-1660499;Reactome: R-HSA-194840 "Interleukin-7 signaling";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Synthesis of PIPs at the plasma membrane";"Rho GTPase cycle" XP_024941002.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024943343.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015604325.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015598289.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_024939806.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_015599245.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_015606820.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015594791.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015584683.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_015585330.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024938341.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_015593481.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_024936567.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015594006.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787 "Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Hedgehog 'off' state" XP_024940693.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236 "Degradation of AXIN";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_024946187.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015587763.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_015591229.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_024939342.1 6 MetaCyc: PWY-6922;MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13 "L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_024944593.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_015585995.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024936550.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_024940273.1 2 Reactome: R-HSA-83936;Reactome: R-HSA-2564830 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"Cytosolic iron-sulfur cluster assembly" XP_015589102.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024937386.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_024938314.1 13 KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-5537 "C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V" XP_015605552.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_015590933.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_024941619.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_015606805.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate" XP_015607756.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_024946365.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015584932.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_024944200.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_024937960.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015596445.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_024936452.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_015606804.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_024941009.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024939048.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015589211.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024944778.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015595447.1 13 KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857 "Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation" XP_015595357.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015586546.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024947320.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015599096.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_015605289.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024943356.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_015584909.1 5 Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221 "RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway" XP_024939945.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_015601598.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_015588800.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_015605918.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_015607466.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015610188.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015603907.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_015601585.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015587544.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015588596.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288 "Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1" XP_015586564.1 5 Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;Reactome: R-HSA-380994 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_015597235.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_024938366.1 4 Reactome: R-HSA-446193;KEGG: 00311+1.21.3.1;MetaCyc: PWY-5629;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Penicillin and cephalosporin biosynthesis";"Isopenicillin N biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_024944172.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_024940503.1 11 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015597896.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015587448.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015589450.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015601627.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015598142.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_024942488.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024940161.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015598229.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_015597479.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones" XP_024947520.1 9 MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7003;Reactome: R-HSA-70263 "Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Gluconeogenesis" XP_015607462.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024938759.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015594470.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015597920.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_015590712.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015602828.1 24 Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-418592 "Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"ADP signalling through P2Y purinoceptor 1" XP_015597640.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_024944871.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024944253.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_015606598.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_015598993.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024935842.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase" XP_015604152.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_015598480.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015600098.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015593906.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015601987.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90 "Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_015599540.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015608260.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015605078.1 4 MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate" XP_024946405.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015601331.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_015590526.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_015605427.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015605954.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_024940924.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024938260.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_015598779.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_024940967.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_015594631.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015587278.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_024941908.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024944460.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024946882.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_024937398.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015597063.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024940351.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015608445.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6 "Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015598049.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_024937854.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024938149.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015586206.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_015585861.1 3 MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation" XP_015605951.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_015597910.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015609556.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015596557.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015595113.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_024939055.1 10 MetaCyc: PWY-7921;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;MetaCyc: PWY-7661;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;MetaCyc: PWY-7979;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377 "Protein O-mannosylation I (yeast)";"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein N-glycosylation (Haloferax volcanii)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_015594865.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_015589296.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015609875.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000 "AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"RAF activation" XP_015592070.1 17 Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-69166 "HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Removal of the Flap Intermediate" XP_015590982.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024946946.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015596300.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015608104.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_024945468.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024945272.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_015586629.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015599531.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_024939673.1 18 Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1483166 "Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Synthesis of PA" XP_015609263.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015589649.1 11 Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1 "Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway" XP_015588357.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024941500.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015590804.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024938094.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015602847.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015610190.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015597832.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_024936700.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015589674.1 26 Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497 "Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_024944924.1 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_024935836.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_015593636.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015590274.1 4 Reactome: R-HSA-6782315;Reactome: R-HSA-156581;Reactome: R-HSA-72764;Reactome: R-HSA-6790901 "tRNA modification in the nucleus and cytosol";"Methylation";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol" XP_015591987.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015596305.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024944893.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024936989.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015607916.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_015605825.1 7 Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"Nephrin family interactions";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins" XP_024941890.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015595722.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_015592158.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_024936603.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015601810.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-3108214 "SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins" XP_015608906.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_024943098.1 4 Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255 "HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis" XP_015598575.1 19 MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538 "Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI" XP_015585684.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024939610.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024942388.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015603943.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_015606958.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024945623.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_015592497.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_015592107.1 5 Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787 "GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state" XP_015585347.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015602432.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015597852.1 7 Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-6596 "Neutrophil degranulation";"Purine metabolism";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I" XP_024937951.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015603025.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015590195.1 3 Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314 "Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex" XP_015587876.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015599888.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_024939605.1 3 Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193 "Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_015589987.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015597226.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015598989.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_015600702.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis" XP_024941675.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_015585741.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015607653.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_024947246.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024945649.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015606082.1 4 MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849;MetaCyc: PWY-5691 "Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin I" XP_024937963.1 9 Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes" XP_015604129.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_024935788.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015588677.1 57 Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827 "Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex" XP_015596558.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015601676.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_024938177.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_015603020.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_015598651.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015607206.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_015604050.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015601556.1 16 Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-6796648;Reactome: R-HSA-112382 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Neddylation";"Vif-mediated degradation of APOBEC3G";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex" XP_015599301.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_015586731.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_015607736.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015596126.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015586630.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015598818.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)" XP_015587907.2 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_015590393.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015587975.1 9 Reactome: R-HSA-196780;Reactome: R-HSA-70263;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146 "Biotin transport and metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism" XP_015601333.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_015585331.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024945687.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015587510.1 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_024937292.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500 "Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle" XP_024935535.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_015599876.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024946579.1 10 Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-7344 "Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis" XP_015602579.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015607641.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015590234.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024939412.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015598766.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_015598427.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_015608891.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_024947656.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-114508 "Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ion homeostasis";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Effects of PIP2 hydrolysis" XP_015598396.1 57 Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541 "Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"UCH proteinases";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway" XP_015597716.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_024936870.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015607385.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_015605459.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015603470.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_015608866.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_024936728.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_015596652.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_015598524.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_015599527.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015585866.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_015595112.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015584853.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015604953.1 5 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-983231 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production" XP_015603230.1 11 Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-389948;Reactome: R-HSA-877312;Reactome: R-HSA-388841;Reactome: R-HSA-9008059;Reactome: R-HSA-114604;Reactome: R-HSA-391160;Reactome: R-HSA-912694;Reactome: R-HSA-210990;Reactome: R-HSA-432142 "Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PD-1 signaling";"Regulation of IFNG signaling";"Costimulation by the CD28 family";"Interleukin-37 signaling";"GPVI-mediated activation cascade";"Signal regulatory protein family interactions";"Regulation of IFNA signaling";"PECAM1 interactions";"Platelet sensitization by LDL" XP_015602249.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024936151.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015607659.1 6 KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_015593521.1 7 MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4 "Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Glycerophospholipid metabolism" XP_015596556.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015602853.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024942375.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_015607059.1 7 MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25 "Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system" XP_015593731.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_024940739.1 6 MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_015598181.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015605819.1 4 KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193 "Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I" XP_024942769.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015603035.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_015588278.1 52 Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091 "Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells" XP_024938874.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015609666.1 13 Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-422356 "PLC beta mediated events";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion" XP_024943193.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_015589778.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015596885.1 8 Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828 "Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis" XP_024941800.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024935771.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015607943.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024944198.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_024945975.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_015594971.1 6 Reactome: R-HSA-173599;MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346 "Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)" XP_024938175.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy" XP_024938603.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015586922.1 12 Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292 "Neutrophil degranulation";"Galactose metabolism";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"MPS VII - Sly syndrome" XP_024945109.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_015608809.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015595289.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_024938158.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_024936320.1 19 Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8963901 "Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"VLDL assembly";"LDL remodeling";"LDL clearance";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Chylomicron clearance";"Chylomicron assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Chylomicron remodeling" XP_024943813.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024938367.1 2 MetaCyc: PWY-5629;KEGG: 00311+1.21.3.1 "Isopenicillin N biosynthesis";"Penicillin and cephalosporin biosynthesis" XP_024946843.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015599692.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_015590170.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA" XP_024938212.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-442982 "Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Ion homeostasis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_024937786.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_024938400.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_015589342.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015607132.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5744;Reactome: R-HSA-196780 "3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Biotin transport and metabolism" XP_015595635.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_015595405.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024936487.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015599454.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation" XP_015600409.1 4 MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14 "Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism" XP_015590801.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015587716.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588 "snRNP Assembly";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_024947327.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_024936369.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_015600196.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_015598652.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015599764.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015606856.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_015608246.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_015600928.1 5 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-201722 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex" XP_024946067.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015599190.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_015588349.1 4 MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_015586092.1 13 MetaCyc: PWY-6842;Reactome: R-HSA-196836;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1 "Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"Glutathione metabolism" XP_015587012.1 5 MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-7082 "Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" XP_015586647.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015589873.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015599945.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015600904.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015598279.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_024944195.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015605816.1 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_015593063.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_015604756.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_024945889.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_015594546.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015595486.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024943347.1 4 MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14 "Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism" XP_015600099.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015596129.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024937240.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_024946622.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_015602040.1 5 MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6 "D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_015588767.1 57 Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-69481 "NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"G2/M Checkpoints" XP_015591085.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68949 "Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin" XP_024938958.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-2467813 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids" XP_015607278.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024938059.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024944406.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015608048.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015598847.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024946885.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_024938099.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015600751.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910 "HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs" XP_024946608.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_024942448.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024936004.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015601052.1 8 MetaCyc: PWY-7524;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391 "Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" XP_024936379.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_024936648.1 2 Reactome: R-HSA-5655302;Reactome: R-HSA-1839117 "Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants" XP_015593727.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_024943075.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024943435.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_015609952.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_015586142.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015605710.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024942284.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015595279.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_015603647.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015588191.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_024942424.1 24 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-432040 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_015593092.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015598570.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs" XP_024935618.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015592796.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_015600523.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015603421.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015599743.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_015598156.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_015601479.1 5 MetaCyc: PWY-5531;MetaCyc: PWY-7159;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_015610382.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_024940282.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_024940720.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015609525.1 26 Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295 "Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation" XP_015596725.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_024947141.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_024938236.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends" XP_015603885.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_024939955.1 10 MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7391 "Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" XP_015602790.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024935976.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_015590711.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015592424.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015597867.1 4 KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219 "Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_015592611.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015598264.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015589794.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015605189.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015595654.1 17 Reactome: R-HSA-5689880;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-4086398;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-168638 "Ub-specific processing proteases";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"Ca2+ pathway";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway" XP_015598027.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015600388.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015604983.1 9 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_024938355.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024939042.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024941802.1 14 KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-611105;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-3781;MetaCyc: PWY-561;MetaCyc: PWY-6728 "Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle" XP_015590671.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" XP_015598823.1 57 Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664 "CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation" XP_015601303.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_024947252.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015600590.1 14 KEGG: 00270+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-7767;MetaCyc: PWY-5104;KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5108;MetaCyc: PWY-5078;Reactome: R-HSA-70895 "Cysteine and methionine metabolism";"L-isoleucine biosynthesis III";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"L-leucine degradation III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis V";"L-isoleucine degradation II";"Branched-chain amino acid catabolism" XP_015610226.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024937518.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_015588633.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_024947672.1 6 MetaCyc: PWY-7442;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-5497;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3 "Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Purine metabolism" XP_015599449.1 5 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660499 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane" XP_015605021.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_015586811.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015595366.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024945573.1 10 KEGG: 05170+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"T cell receptor signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"Human papillomavirus infection";"TNFR1-induced NFkappaB signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_024935839.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_024939818.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015585253.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_015586699.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015586778.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_015586749.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015602757.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015599709.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_015596211.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_024941408.1 9 Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"HS-GAG degradation" XP_015607847.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_015593469.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_015598661.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024939170.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024945575.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_024937190.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024938589.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_015602767.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015602832.1 24 Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-8964315 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK" XP_015598250.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_015596488.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)" XP_024946186.1 3 KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725 "Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation" XP_015585163.1 6 Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8963889 "ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes" XP_024942674.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_015592180.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015599142.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_024941913.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015589995.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_015591477.1 3 Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398 "cGMP effects";"Rap1 signalling";"Ca2+ pathway" XP_024946966.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015598654.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024943573.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_024945802.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015602685.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_024941580.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015594995.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_024937522.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_015597914.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015598040.1 9 MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-5744 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation" XP_015600885.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_015588473.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_015590612.1 7 Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;MetaCyc: PWY-6134;MetaCyc: PWY-7158;Reactome: R-HSA-2160456 "Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V";"Phenylketonuria" XP_024937834.1 9 Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69205;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-174411 "Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"DNA replication initiation";"G1/S-Specific Transcription";"Processive synthesis on the lagging strand";"Polymerase switching";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere" XP_015587267.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015607876.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_015585437.1 10 KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11 "Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism" XP_015587271.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015594534.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015598682.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015590248.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910 "HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs" XP_015601011.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015592426.1 11 Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6549;MetaCyc: PWY-5675 "Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)" XP_015591293.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_024935718.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024942364.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_024938751.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024938924.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_015587871.1 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-6728 "Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle" XP_015605673.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024946627.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024937005.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024946886.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_015595438.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015591158.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_024940766.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015597876.1 33 Reactome: R-HSA-6782135;Reactome: R-HSA-69202;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-69656;Reactome: R-HSA-69231;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-69273;Reactome: R-HSA-167158;Reactome: R-HSA-8939236 "Dual incision in TC-NER";"Cyclin E associated events during G1/S transition";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin D associated events in G1";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the HIV-1 Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_015594158.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015610534.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism" XP_015592461.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024945170.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015596716.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015596904.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015609183.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015595687.1 4 KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030 "Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_015597807.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_015587665.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_015605937.1 12 KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;MetaCyc: PWY-6932 "Selenocompound metabolism";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfate activation for sulfonation";"Selenate reduction" XP_024936437.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"Hedgehog 'off' state" XP_015601239.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_015610334.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015600435.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695 "IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Neutrophil degranulation" XP_015590999.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015589081.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_024947235.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_015593999.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015609769.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_015600586.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_024940381.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015585375.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024945397.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024935690.1 6 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" XP_015607872.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_024947796.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015603916.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015609718.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_024945645.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024936872.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024945463.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_015601244.1 10 Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00562+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00010+5.3.1.1;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70263 "Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Inositol phosphate metabolism";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Gluconeogenesis" XP_015588970.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015591967.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015598548.1 4 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-9031525 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake" XP_015598010.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015588586.1 7 MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-882 "GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_015597194.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024940485.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_024939866.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_024944533.1 6 MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433 "Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation" XP_015607747.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024945556.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015607397.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_024940417.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_015604630.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC" XP_015595425.1 25 Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-381771;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-418592 "Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"ADP signalling through P2Y purinoceptor 1" XP_024947336.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015609209.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_015585456.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015586957.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_015595348.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_024942930.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015593729.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015592897.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015586786.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_015600757.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015588432.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919 "Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils" XP_015589435.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_015604280.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024946613.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_015599407.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015598212.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015591182.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024945344.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017 "Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_015595675.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015601012.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015605191.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015604304.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_024946858.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024945513.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_024944784.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024945658.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024944001.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5610787 "Activation of SMO";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state" XP_015596301.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_015592013.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_015594764.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024940205.1 5 MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_015593654.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015598762.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_015598188.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024941107.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024935996.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015610583.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015589356.1 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_024935809.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_015602045.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_015602950.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015597835.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_015594927.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024944697.1 4 MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23 "Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism" XP_015589552.1 7 Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6385;MetaCyc: PWY-6470 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)" XP_015607882.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024945825.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_015602152.1 7 Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-201681 "Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"PCP/CE pathway";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT" XP_024936496.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015589212.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015604411.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_015597700.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015594732.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015589090.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015601407.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_024935999.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015609351.1 13 MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_015590635.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024941322.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015600040.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_015590030.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_015606420.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015606190.1 18 MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925 "Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG" XP_024947237.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015607911.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015606157.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_015590971.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_015590640.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024944049.1 5 MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-922 "Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I" XP_015590956.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_024947002.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_015599959.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_024935483.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_015601576.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_024941983.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_024937358.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024935686.1 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_015603082.1 6 Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis" XP_015586905.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_024946775.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024935505.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_015597549.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135 "Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation" XP_015599883.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015608238.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_015604843.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015604550.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015610432.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015607523.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015601179.1 7 KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;MetaCyc: PWY-6471;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15 "Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis" XP_015599379.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_024943495.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024938944.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_015594925.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024944408.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015589965.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024947821.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_024942036.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024937521.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_015602356.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015605017.1 6 Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900 "Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_015589875.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015609509.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_024944384.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024935719.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015590144.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_024936218.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_015609807.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015595322.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015587151.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015584983.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_015596377.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_024944564.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_015601359.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_024939598.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_015589477.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_024936705.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_015607526.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015585504.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015608880.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015605749.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_015597190.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_015600367.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_024939725.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_015596954.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_015609020.1 6 Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-416993;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_024939562.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_015602621.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015607603.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015586615.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_024940061.1 14 KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1 "Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Respiratory electron transport";"Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_015590143.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_015602991.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015591829.1 42 Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-2559580 "DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"HCMV Late Events";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"Packaging Of Telomere Ends";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones";"Meiotic synapsis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"Oxidative Stress Induced Senescence" XP_015607184.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015588315.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_015589462.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878 "Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport" XP_024940941.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015603640.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015601675.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_024939778.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_024940451.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_024945238.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_015607507.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015601018.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015599315.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_024944873.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015608358.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)" XP_024943253.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_015594432.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015610128.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015598076.1 12 KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599 "Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_024943240.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015600266.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_015602954.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024945106.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_015595358.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015602253.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015593167.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024943120.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015585402.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024946180.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015608346.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_024942419.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015595964.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024938861.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015610220.1 7 MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516 "3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane" XP_015598217.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_024940160.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015591349.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_015593642.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_015585685.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015600843.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015590683.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_015587941.1 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" XP_015595008.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974 "Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway" XP_024936148.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015596389.1 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024947800.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015598197.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_024940508.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_024942846.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024936202.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015599396.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015601522.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024938600.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_015599093.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_024944962.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015591401.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_024947757.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015610235.1 6 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_015588538.1 9 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015585202.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015604039.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_015585600.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024938440.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015610581.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_024943659.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024938230.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948 "Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants" XP_015586003.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024937232.1 10 MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171 "1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis" XP_015604754.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_015597137.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_024937468.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_024943939.1 20 MetaCyc: PWY-7176;MetaCyc: PWY-7227;Reactome: R-HSA-380320;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7220;Reactome: R-HSA-499943 "UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"CMP phosphorylation";"Pyrimidine metabolism";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates" XP_024938093.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015609278.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_015591223.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_015607713.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_024945440.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015598541.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024945576.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024946745.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_024942233.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_024936682.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_015586181.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015595542.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024947580.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015602298.1 12 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483 "Human papillomavirus infection";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Thermogenesis";"Macroautophagy";"Activation of AMPK downstream of NMDARs" XP_015584895.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024940210.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015596331.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis" XP_024942169.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024943114.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015594014.1 13 MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_024942237.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015598442.1 9 Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-6794361;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Long-term potentiation";"Neurexins and neuroligins";"Ras activation upon Ca2+ influx through NMDA receptor" XP_015609711.1 5 Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211976 "Xenobiotics";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Endogenous sterols" XP_015593129.2 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_015598469.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00620+2.3.1.12;KEGG: 00010+2.3.1.12;KEGG: 00020+2.3.1.12;Reactome: R-HSA-389661 "Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_024945016.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024947519.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_015585397.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_015585169.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_024936874.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_024947402.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_015590433.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_024941579.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015600113.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_024938905.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015601886.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion" XP_015604384.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" XP_015606894.1 6 Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751 "Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity" XP_015599744.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024939059.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_024942606.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015592702.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_024943355.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_015595704.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024940139.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_015588072.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015587641.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_024938867.1 5 Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5358346 "ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hedgehog ligand biogenesis" XP_015591178.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024939309.1 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" XP_024947587.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_015602387.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_015600831.1 32 Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-6803529;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167200 "Formation of RNA Pol II elongation complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_024940092.1 18 Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-6796648;Reactome: R-HSA-5693568;MetaCyc: PWY-7511;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5689901;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Protein ubiquitination";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Metalloprotease DUBs";"HDR through Single Strand Annealing (SSA)" XP_015597014.1 3 Reactome: R-HSA-1296072;Reactome: R-HSA-5576890;Reactome: R-HSA-5576893 "Voltage gated Potassium channels";"Phase 3 - rapid repolarisation";"Phase 2 - plateau phase" XP_024946369.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_024941942.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015604855.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024937940.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015596299.1 10 Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828 "Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Ub-specific processing proteases";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis" XP_015607022.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_015592661.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_015595926.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024936057.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015602314.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" XP_015609826.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015609688.1 4 Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_015589800.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015593113.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015607950.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_015594868.1 12 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"MHC class II antigen presentation" XP_024936134.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015590767.1 11 KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-1632852;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-168138 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Macroautophagy";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade" XP_015584904.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024937117.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_024943163.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_015605461.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024936446.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015595007.2 56 Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768 "CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_024941610.1 4 Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" XP_015603178.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_015608813.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015601233.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_015592139.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024945539.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_015585208.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024940380.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015587445.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_015602440.1 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015602242.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015597481.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394 "UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER" XP_015607996.1 3 Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_015589107.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015592920.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015604738.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024942509.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015599457.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_024936730.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_015602066.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015586134.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015586808.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_024943203.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_015605763.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_015586606.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_015590814.1 8 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015596666.1 5 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015602906.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024943558.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015598297.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_024941582.1 1 Reactome: R-HSA-156581 "Methylation" XP_015587066.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015601480.1 5 MetaCyc: PWY-7159;MetaCyc: PWY-7766;MetaCyc: PWY-5531;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_015585649.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_015586230.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_015598355.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024944465.1 7 KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00281+4.1.3.4;Reactome: R-HSA-77111;KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074 "Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Peroxisomal protein import";"Geraniol degradation";"Synthesis of Ketone Bodies";"Butanoate metabolism";"Mevalonate degradation" XP_015604771.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015587250.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015603600.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015599097.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024947574.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_015597845.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015609184.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_015602851.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015609038.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_015590829.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_024947263.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015597558.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015608545.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_024940504.1 11 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway" XP_015609390.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_015600820.1 15 Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_024940867.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015610124.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015600703.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis" XP_015602085.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_015603979.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015593684.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015587966.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015606556.1 5 KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation" XP_024941875.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024936597.1 7 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5685939 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)" XP_024947236.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_015594552.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015592376.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015594659.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015597750.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015594221.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015598429.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_015598067.1 12 KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527 "Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Stachyose degradation" XP_024941069.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015589368.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_024936108.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015598955.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159 "TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling" XP_015592051.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_015600829.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015601995.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_015600005.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_024944781.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_024936366.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_024935784.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015601373.1 6 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport" XP_015588847.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_015596731.1 10 Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-111459 "Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage" XP_015586573.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015590633.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015600192.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_024938755.1 6 MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_015605912.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_015599095.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_024946368.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015601083.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015593226.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_015591123.1 6 Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690 "PPARA activates gene expression";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events" XP_024940989.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_024947648.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485 "Effects of PIP2 hydrolysis";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis" XP_015601399.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015589258.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015594645.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_015592501.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024937079.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_015589692.1 8 KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1 "Fructose and mannose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis" XP_015607866.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619 "Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis" XP_024944675.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_015592938.1 7 MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-7625 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)" XP_015595778.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_015590826.1 52 Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-73980;Reactome: R-HSA-6803529;Reactome: R-HSA-76061;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-73780;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-113418;Reactome: R-HSA-76066;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-73762;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-427413 "Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Chain Elongation";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"RNA Polymerase I Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"NoRC negatively regulates rRNA expression" XP_015587330.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024942212.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_024942669.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015588943.1 2 Reactome: R-HSA-83936;Reactome: R-HSA-196843 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"Vitamin B2 (riboflavin) metabolism" XP_015590634.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015600821.1 15 Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939 "DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)" XP_015593889.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_015600692.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis" XP_015595079.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_024944083.1 33 Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-159236 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024936363.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_015593948.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015594344.1 4 KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300 "Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA" XP_024942493.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015609299.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_015609246.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_015600500.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015598717.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_024943313.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_024936430.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024936236.1 8 KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Galactose metabolism" XP_015590493.1 4 Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Cristae formation" XP_015598095.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776 "HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape" XP_015598216.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_024943660.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015588869.1 5 KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Gluconeogenesis" XP_015589924.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6" XP_015584687.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;Reactome: R-HSA-1475029 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide" XP_024944861.1 5 KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22 "Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism" XP_015603746.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_024946702.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_015598357.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015602848.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015598986.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_015587272.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024942649.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_015589043.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_024947355.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024947220.1 24 Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483 "EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs" XP_015586045.1 52 Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-76061;Reactome: R-HSA-6803529;Reactome: R-HSA-73980;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-749476;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-168325;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-73780;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-427413;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-5578749;Reactome: R-HSA-167158;Reactome: R-HSA-167161 "RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Termination";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Abortive And Retractive Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Chain Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NoRC negatively regulates rRNA expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"Transcriptional regulation by small RNAs";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation" XP_015594862.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_015608656.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_015585658.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015602980.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_015594795.1 7 Reactome: R-HSA-212436;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Generic Transcription Pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015589164.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_024946819.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_024942522.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024938226.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736 "HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors" XP_015598525.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_015602299.1 12 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway" XP_015598277.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015598713.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_015608010.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015610182.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015585299.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015605911.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation" XP_015594644.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_024943254.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_015602897.1 39 Reactome: R-HSA-5654720;Reactome: R-HSA-109704;Reactome: R-HSA-190375;Reactome: R-HSA-190322;Reactome: R-HSA-5654710;Reactome: R-HSA-190372;Reactome: R-HSA-5654227;Reactome: R-HSA-5654732;Reactome: R-HSA-190373;Reactome: R-HSA-5654706;Reactome: R-HSA-1839130;Reactome: R-HSA-5658623;Reactome: R-HSA-2219530;Reactome: R-HSA-2033514;Reactome: R-HSA-1257604;Reactome: R-HSA-5654221;Reactome: R-HSA-5654688;Reactome: R-HSA-5654704;Reactome: R-HSA-5654228;Reactome: R-HSA-5655302;Reactome: R-HSA-5654733;Reactome: R-HSA-5654695;Reactome: R-HSA-5654687;Reactome: R-HSA-5654712;Reactome: R-HSA-5654719;Reactome: R-HSA-190371;Reactome: R-HSA-5654727;Reactome: R-HSA-5654726;Reactome: R-HSA-5654693;Reactome: R-HSA-2033519;Reactome: R-HSA-5654699;Reactome: R-HSA-1839122;Reactome: R-HSA-8853338;Reactome: R-HSA-5654689;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5655253;Reactome: R-HSA-5654219 "PI-3K cascade:FGFR4";"PI3K Cascade";"FGFR2c ligand binding and activation";"FGFR4 ligand binding and activation";"PI-3K cascade:FGFR3";"FGFR3c ligand binding and activation";"Phospholipase C-mediated cascade, FGFR3";"Negative regulation of FGFR3 signaling";"FGFR1c ligand binding and activation";"FRS-mediated FGFR3 signaling";"Signaling by activated point mutants of FGFR3";"FGFRL1 modulation of FGFR1 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"FGFR3 mutant receptor activation";"PIP3 activates AKT signaling";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR1";"SHC-mediated cascade:FGFR3";"Phospholipase C-mediated cascade, FGFR4";"Signaling by FGFR1 in disease";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR2";"Downstream signaling of activated FGFR1";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR4";"FGFR3b ligand binding and activation";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR1 signaling";"FRS-mediated FGFR1 signaling";"Activated point mutants of FGFR2";"SHC-mediated cascade:FGFR2";"Signaling by activated point mutants of FGFR1";"Signaling by FGFR3 point mutants in cancer";"PI-3K cascade:FGFR1";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"Signaling by FGFR2 in disease";"Phospholipase C-mediated cascade: FGFR1" XP_015593956.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-156711 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events" XP_015584685.1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115 "Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_024945318.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015604093.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024940738.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_024941516.1 9 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-193648 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"NRAGE signals death through JNK" XP_015589791.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015585479.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024938167.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_024941480.1 5 Reactome: R-HSA-2022377;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026 "Metabolism of Angiotensinogen to Angiotensins";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)" XP_015585217.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_015589938.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015606079.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024940036.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription" XP_015603160.1 3 MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12 "Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_015590025.1 7 MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system" XP_015595045.1 10 Reactome: R-HSA-2644606;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription" XP_015598519.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_015594412.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015604783.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015585101.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024937699.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135 "Regulation of TP53 Degradation";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Dual incision in TC-NER" XP_015585890.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015608026.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015596835.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015606239.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18 "Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015593441.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"G alpha (q) signalling events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule" XP_024938171.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_024935682.1 6 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_015587344.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_024940436.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_015605193.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015603686.1 1 MetaCyc: PWY-6938 "NADH repair" XP_024944927.1 5 Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295 "Kinesins";"Intraflagellar transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation" XP_024946272.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015607163.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024946188.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015591627.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_015603019.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_015603956.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024936557.1 12 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway" XP_024942472.1 10 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_015587579.1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015597922.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_024937939.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015603707.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_024945000.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015594603.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-879415 "Neutrophil degranulation";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling" XP_015593330.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes" XP_015585793.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_024937347.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015597987.1 7 Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"ECM proteoglycans" XP_015604126.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_015593201.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024937938.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015591435.2 8 KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9617324 "Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_024942513.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015604866.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024944351.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015606249.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024942417.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024935570.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_024946908.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024937047.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_015607599.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015594090.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_015594044.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth" XP_024946984.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015595452.1 4 Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-166058 "MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_015595325.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN" XP_015597104.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_024936174.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015609911.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5467340 "Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex" XP_015608657.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_015595404.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649 "rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation" XP_024936123.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_024938797.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_015587567.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Photosynthesis";"ATP biosynthesis" XP_015594020.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024943334.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015609886.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024942950.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015591077.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015605872.1 11 Reactome: R-HSA-140534;Reactome: R-HSA-933543;Reactome: R-HSA-75158;Reactome: R-HSA-5357786;Reactome: R-HSA-2562578;Reactome: R-HSA-5218900;Reactome: R-HSA-69416;Reactome: R-HSA-75157;Reactome: R-HSA-3371378;Reactome: R-HSA-9013957;Reactome: R-HSA-5213460 "Caspase activation via Death Receptors in the presence of ligand";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TRAIL signaling";"TNFR1-induced proapoptotic signaling";"TRIF-mediated programmed cell death";"CASP8 activity is inhibited";"Dimerization of procaspase-8";"FasL/ CD95L signaling";"Regulation by c-FLIP";"TLR3-mediated TICAM1-dependent programmed cell death";"RIPK1-mediated regulated necrosis" XP_015604293.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015600604.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_024938346.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722 "Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis" XP_015606139.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_024939380.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015607061.1 10 MetaCyc: PWY-7849;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;MetaCyc: PWY-5691 "Urate conversion to allantoin III";"Retinoid metabolism and transport";"Neutrophil degranulation";"Purine metabolism";"Urate conversion to allantoin II";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I" XP_015598710.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_015600211.1 3 Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism" XP_015609009.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024937226.1 10 KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11 "Galactose metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism" XP_015589224.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015585687.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015605439.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015595488.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015598082.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015609803.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_024943148.1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519 "ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"Estrogen-dependent gene expression" XP_024938894.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_024945491.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015596539.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_015586545.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015593471.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024942369.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_015598176.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis" XP_015602313.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" XP_015595862.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015594398.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_015600484.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015595536.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_024944908.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015594376.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015599325.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"Ion channel transport";"Amino acids regulate mTORC1" XP_015585318.1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_024942346.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015598470.1 7 Reactome: R-HSA-5362517;KEGG: 00620+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12 "Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis" XP_015605009.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024947766.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024942941.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015588803.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_024936128.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015596457.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015601667.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_024940605.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_024940164.1 9 MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_015607505.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015598508.1 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_024940936.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_024943007.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015594454.1 17 Reactome: R-HSA-167200;Reactome: R-HSA-167158;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-112382;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Th1 and Th2 cell differentiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation" XP_015595492.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015608916.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024941978.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955 "Neutrophil degranulation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_015601053.1 8 MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_015607473.1 10 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6361;MetaCyc: PWY-4661 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_015586932.1 6 Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916 "MPS VII - Sly syndrome";"HS-GAG degradation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Hyaluronan uptake and degradation" XP_024947873.1 2 Reactome: R-HSA-419771;Reactome: R-HSA-8951664 "Opsins";"Neddylation" XP_015603777.1 7 KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol" XP_024941995.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_024944907.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_024947142.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_015609748.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_024938241.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_015603213.1 10 Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-427413 "MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression" XP_015601878.2 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_024939404.1 12 Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-450408 "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_015605740.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854 "Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis" XP_024943516.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015596436.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_024947722.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_024937519.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_024936181.1 10 MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667 "Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I" XP_015591657.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354 "Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Lipophagy" XP_024940986.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_024947758.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015607638.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_024946961.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024940371.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_015595531.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015608655.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015601680.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015604645.1 17 KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37 "Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Methane metabolism" XP_024936649.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_015607398.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_024943601.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015585166.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015593263.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_015599582.1 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891 "Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)" XP_015607808.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015596355.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024938895.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_024940846.1 18 Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417 "Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Synthesis of PA";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)" XP_015594448.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015589077.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_015599140.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015586006.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_024945423.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_024935583.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015589495.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015594793.1 29 Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_024945844.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_024936456.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_015593814.2 14 MetaCyc: PWY-6969;MetaCyc: PWY-3781;MetaCyc: PWY-561;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7279 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Respiratory electron transport";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)" YP_002889394.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015602612.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024945391.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015595871.1 3 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation" XP_015597017.1 3 Reactome: R-HSA-5576893;Reactome: R-HSA-1296072;Reactome: R-HSA-5576890 "Phase 2 - plateau phase";"Voltage gated Potassium channels";"Phase 3 - rapid repolarisation" XP_015603280.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024936558.1 12 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Rho GTPase cycle";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling" XP_015586690.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015591440.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_015598135.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015605717.1 33 Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159230 "EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Mitotic Prometaphase";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA" XP_015592484.1 10 MetaCyc: PWY-7328;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-6317;Reactome: R-HSA-70370 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism" XP_015587119.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_015607108.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024941704.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_024936081.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_015592433.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015608396.1 19 Reactome: R-HSA-192823;Reactome: R-HSA-5368286;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-5389840;Reactome: R-HSA-72649;Reactome: R-HSA-5419276;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Mitochondrial translation initiation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Mitochondrial translation elongation";"Translation initiation complex formation";"Mitochondrial translation termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015594141.1 5 MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_015595280.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_024941304.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015592149.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015585895.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015589611.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955 "Interferon gamma signaling";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_015593431.1 9 MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_024941799.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015596288.1 16 Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-9022692 "Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity" XP_015590570.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015609196.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015598765.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642 "Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_024941007.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024942030.1 5 MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317 "Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)" XP_015600227.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024945454.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024941735.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024940866.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_015595006.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_024947862.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_015602706.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015596008.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015602632.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015584865.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_024939448.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015601992.1 6 Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-110373 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_015609126.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015606132.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015597376.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024940947.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_024943112.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024946805.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015586857.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_024940449.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_024935804.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_024935577.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024946034.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015605821.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage" XP_015586670.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015607295.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_024938416.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015586894.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_024937455.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_015602625.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_015604511.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015608261.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015610403.1 10 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"RSK activation";"Recycling pathway of L1";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_015604587.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015604568.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015610589.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015587457.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015595639.1 2 KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_015585832.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015594475.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015609870.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751 "Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated" XP_024944359.1 24 Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-392851;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-420092 "G alpha (z) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Prostacyclin signalling through prostacyclin receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors" XP_015607460.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024945360.1 17 MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37 "Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes" XP_015599229.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024935612.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024938173.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion" XP_015591071.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015599932.1 16 Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-3134963;Reactome: R-HSA-975155;Reactome: R-HSA-209543;Reactome: R-HSA-975871;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-1257604;Reactome: R-HSA-1810476;Reactome: R-HSA-9020702;Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-1236974;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558 "MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 dependent cascade initiated on endosome";"p75NTR recruits signalling complexes";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"PIP3 activates AKT signaling";"RIP-mediated NFkB activation via ZBP1";"Interleukin-1 signaling";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"ER-Phagosome pathway";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_015603500.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024937776.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024943268.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024939611.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024943227.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949 "E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin" XP_015596881.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_024940510.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_015590856.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015590641.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024947717.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945 "PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds" XP_024945455.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015587594.1 37 Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-2132295;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-9639288;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-204005;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-983170 "Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"MHC class II antigen presentation";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amino acids regulate mTORC1";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"COPII-mediated vesicle transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_015590203.1 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" XP_024947297.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015589416.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_024945514.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015589797.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024939045.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015592733.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_015610316.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015601133.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015604727.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion" XP_015605359.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015593685.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024945179.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_015609115.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_024942415.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015605348.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015602250.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015586364.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015598306.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015597469.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Mitotic Telophase/Cytokinesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_015595373.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024943749.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024938344.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722 "Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis" XP_015597503.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015586155.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_015608942.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015594461.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_015609675.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485 "Effects of PIP2 hydrolysis";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Ion homeostasis";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis" XP_024938726.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015589218.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024937982.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024940168.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015610217.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_015595525.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_015605006.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024942277.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015590224.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_015610457.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation" XP_024938256.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_015608247.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015601503.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015603072.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024942391.1 4 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-9031525 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake" XP_015587695.1 4 KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism" XP_015589805.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024941673.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015593903.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" XP_024947276.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015585477.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024940343.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015590931.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_015595022.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_015601673.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_015601224.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_024939628.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015603901.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015584886.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins" XP_015602756.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024937587.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814 "Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes" XP_015591277.1 57 Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174178 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_024942366.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_015592729.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_015596304.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015604527.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015603543.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism" XP_015597082.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015603169.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_024942187.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_015588299.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_015609560.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_024937332.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_015600038.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_024938218.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000 "Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Ion homeostasis";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"RAF activation" XP_015609338.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024942774.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015600354.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015605288.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024944586.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_024942188.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase" XP_015607291.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015605719.1 33 Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531 "SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus" XP_015591650.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174084 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_015594576.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_024945618.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015605061.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_015592371.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015602695.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015595362.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015607684.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024938431.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_015594759.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015596804.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662 "TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism" XP_015588836.1 17 Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789 "Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_024941469.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379 "ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"HCMV Late Events" XP_024937099.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage" XP_015606108.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_015591535.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015604967.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015606913.1 7 Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-983168;Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607 "G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends" XP_015603185.1 20 MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-7291 "(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)" XP_015585730.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024941502.1 9 Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253 "HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_024936505.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015586762.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015604361.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_024942137.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015587488.1 8 Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6" XP_015596434.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_024943105.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024937252.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_024940908.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015606620.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_015608313.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015605913.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_024942330.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015605301.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015606873.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015601201.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015592474.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_015594693.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015586233.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_024943636.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_015597544.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955 "Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_015601838.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015594658.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024939708.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024935876.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015595318.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_024939416.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015596560.1 5 Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-8951664 "UCH proteinases";"Iron uptake and transport";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"Neddylation" XP_015604565.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015590233.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015595299.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015608581.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015587723.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_024939384.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_024936266.1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_015594347.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015590937.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_024944986.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_024938387.1 8 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_024947507.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_024938771.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024945155.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015597708.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024944162.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015588540.1 9 KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_015608867.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_024943905.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024936056.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015595547.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015595077.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_015597908.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015586704.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_024943056.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015610127.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015609512.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015601385.1 11 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_024937193.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_024939179.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation" XP_015588990.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_024943060.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015596063.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_024938790.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_024941621.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_015604035.1 4 KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50 "Arginine and proline metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III";"Cysteine and methionine metabolism" XP_015585301.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015593603.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_015610125.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015586061.1 3 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation" XP_024942646.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_015597712.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015597710.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015604410.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015606652.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024946182.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015609234.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015592175.1 7 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway" XP_015591693.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_015609130.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024936072.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_024943255.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_015598576.1 6 KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Galactose metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" XP_015603117.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015588958.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015591357.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-2467813 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids" XP_015591908.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_024937914.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024936303.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015596296.1 10 Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-6807004 "Ub-specific processing proteases";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity" XP_024940976.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015606223.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_024945696.1 4 Reactome: R-HSA-167160;Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-77075 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE" XP_015595122.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015589473.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015594699.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015599747.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015607499.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024941077.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_015588611.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024937680.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation" XP_024947554.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015591042.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024943044.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015597066.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015599993.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase" XP_024936805.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_015607929.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis" XP_015601404.1 5 Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_024946617.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_024937237.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015604284.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_015598875.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_024947088.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015601066.1 4 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_015594543.1 11 Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-171007 "activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"p38MAPK events" XP_015598520.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_015586910.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_024945361.1 17 KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37 "Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism" XP_015598140.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_015606133.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015607337.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214 "Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins" XP_024940444.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_015601849.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015598143.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_015608905.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_015595606.1 4 KEGG: 00633+2.3.1.5;KEGG: 00983+2.3.1.5;KEGG: 00232+2.3.1.5;Reactome: R-HSA-156582 "Nitrotoluene degradation";"Drug metabolism - other enzymes";"Caffeine metabolism";"Acetylation" XP_015599475.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_015587832.1 5 KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis" XP_015586575.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015609122.1 8 KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;MetaCyc: PWY-5723 "Pentose phosphate pathway";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt" XP_015590035.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024940912.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024945817.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015594469.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015599187.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024944870.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_024947771.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015588472.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_024940448.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_024936149.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015588642.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_024945062.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_015595694.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_015598763.2 6 Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_015602184.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_024944751.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_015591313.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015589321.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015589007.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_015593368.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_015589216.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015595171.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_015596280.1 16 Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation" XP_015593802.1 17 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5358565;Reactome: R-HSA-110314 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex" XP_015602393.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_024936488.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_015590555.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015600344.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024940588.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015586229.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_015590708.1 13 MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-7709 "Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"(3R)-linalool biosynthesis" XP_015602209.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_015609296.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_015600130.1 5 MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20 "Folate transformations II (plants)";"Folate transformations I";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes" XP_024941141.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_015609180.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015604288.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_024936368.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_024936129.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024944931.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5620924 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Intraflagellar transport" XP_015588835.1 17 MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;MetaCyc: PWY-5743;MetaCyc: PWY-4381;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780 "Jadomycin biosynthesis";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"Propanoate metabolism";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Biotin transport and metabolism" XP_015605157.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_015609676.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-381676 "Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_015587013.1 5 MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)" XP_024940913.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015606798.1 20 KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852 "Human papillomavirus infection";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"PIP3 activates AKT signaling";"Macroautophagy" XP_015606954.1 4 KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247 "beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids" XP_015604366.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015584706.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015602396.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024944487.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015595724.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015606138.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_015607156.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015597984.1 7 Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"ECM proteoglycans" XP_024941705.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_015589429.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_015600427.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_015588826.1 17 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015590040.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-72731 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP" XP_015602986.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024936053.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015602350.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015609799.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_024941979.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695 "Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation" XP_015588768.1 57 Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174154 "SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Neutrophil degranulation";"Vpu mediated degradation of CD4";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin" XP_024940344.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024940684.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015588212.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_024940445.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_024943980.1 3 Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999 "Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_015608336.1 2 Reactome: R-HSA-192456;Reactome: R-HSA-975634 "Digestion of dietary lipid";"Retinoid metabolism and transport" XP_015595491.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024946910.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015596740.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015596876.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015587777.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_015593366.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate" XP_015588651.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638 "RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_024943052.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_015586256.1 4 KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis" XP_024943346.1 4 KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14 "Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism" XP_015586830.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_015607311.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_024943679.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015593093.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_024935456.1 6 MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10;KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;Reactome: R-HSA-446210 "CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine" XP_015594547.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015586943.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015605760.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_015591663.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_024938337.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_015584679.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024945969.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015607564.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024940793.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015587232.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024940925.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024939709.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015600097.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015609224.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_015597078.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015597592.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_024941059.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_024942370.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_015589041.1 57 Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425 "Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1" XP_024946181.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024937977.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015604603.2 21 MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00983+2.7.4.6;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7219;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7226 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Thiamine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_024943269.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024947765.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_024946774.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_024943271.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015590067.1 14 Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169 "Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Polymerase switching";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis" XP_015588319.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_024943800.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024937913.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015609326.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_024937879.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015587565.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_024944413.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015587799.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_015601238.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_015609672.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5578775 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis" XP_024942648.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_015602200.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015594735.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015609293.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_015596182.1 4 MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation" XP_015595230.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015592989.1 18 MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166 "Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Ether lipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Synthesis of PA" XP_015593225.1 6 Reactome: R-HSA-6787450;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_015595383.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015609511.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024938830.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015595590.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_015597639.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_024941854.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13 "Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione metabolism" XP_015588708.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_024937293.1 7 MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis" XP_015601035.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024936194.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_024938596.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_024939576.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_015587972.1 9 Reactome: R-HSA-196780;Reactome: R-HSA-70263;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142 "Biotin transport and metabolism";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_024939144.1 6 MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-6952 "Glycerol degradation I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophosphodiester degradation" XP_024945643.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_015609472.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015608525.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_024945071.1 4 MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59 "N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_015595183.1 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by Hippo";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_024944963.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_015595338.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_015597941.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015609486.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015609483.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024944110.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015605956.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_015587187.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015587402.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511 "Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination" XP_015607651.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_015600952.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_015587409.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015592633.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_024947792.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024937057.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015602684.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024941643.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_024938915.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015605766.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_024945961.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015586154.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_015609840.1 1 Reactome: R-HSA-419771 "Opsins" XP_024943419.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_024936096.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_015590017.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_015604498.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471 "Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB" XP_024946157.1 1 Reactome: R-HSA-445355 "Smooth Muscle Contraction" XP_024939214.1 5 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-9609523 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_024936454.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_015602296.1 12 Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"PI3K-Akt signaling pathway";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection" XP_015585677.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015609193.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015586543.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015598272.1 14 KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254 "Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Respiratory electron transport";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)" XP_024944275.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_015597717.1 4 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_024947563.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_015594140.1 5 Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;MetaCyc: PWY-922 "Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I" XP_015609598.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015607879.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041 "Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" XP_015609013.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015606484.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024939401.1 12 Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-1169408 "mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism" XP_015610530.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379 "ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres" XP_015594222.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015605217.2 6 Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900 "Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_015597633.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_015608403.1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" XP_015599568.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015606481.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015607918.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_015598567.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024938426.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_024944160.1 18 Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803 "Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing" XP_024936500.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015594923.1 14 Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167158 "RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex" XP_015609839.1 1 Reactome: R-HSA-419771 "Opsins" XP_024937768.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015591547.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015594244.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_024940737.1 6 KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_015602740.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015610587.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015599758.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_015585009.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_015597227.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015599077.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024940789.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015607934.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_024939334.1 7 Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" XP_024946610.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_015609873.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_015605693.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015587539.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_015585827.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015600353.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015604352.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024945563.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015597480.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones" XP_024938940.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_024941231.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015605216.2 6 Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067 "Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_015594085.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer" XP_015600507.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_015609541.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024945424.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_024937334.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_015603190.1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription" XP_015585831.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015600371.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_015589544.1 33 KEGG: 00592+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-5480;MetaCyc: PWY-6587;MetaCyc: PWY-6802;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5078;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-6871;MetaCyc: PWY-7111;MetaCyc: PWY-7013;MetaCyc: PWY-7798;MetaCyc: PWY-5076;KEGG: 00982+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5486;Reactome: R-HSA-71384;MetaCyc: PWY-6313;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-5751;MetaCyc: PWY-3162;MetaCyc: PWY-6333;MetaCyc: PWY-5079;KEGG: 00980+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00830+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-1801 "alpha-Linolenic acid metabolism";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to ethanol III";"Salidroside biosynthesis";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"L-isoleucine degradation II";"Naphthalene degradation";"Butanol and isobutanol biosynthesis (engineered)";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"(S)-propane-1,2-diol degradation";"Protein S-nitrosylation and denitrosylation";"L-leucine degradation III";"Drug metabolism - cytochrome P450";"Methane metabolism";"Pyruvate fermentation to ethanol II";"Ethanol oxidation";"Serotonin degradation";"Tyrosine metabolism";"L-methionine degradation III";"Phenylethanol biosynthesis";"L-tryptophan degradation V (side chain pathway)";"Acetaldehyde biosynthesis I";"L-phenylalanine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Glycine, serine and threonine metabolism";"Fatty acid degradation";"L-valine degradation II";"Retinol metabolism";"Chloroalkane and chloroalkene degradation";"Formaldehyde oxidation II (glutathione-dependent)" XP_024941509.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024943234.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_024940911.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015607687.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015604787.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015591138.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-6823;MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis" XP_024937959.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024946501.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015592475.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_015608881.1 4 MetaCyc: PWY-7250;Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism" XP_024943448.1 7 MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445 "Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation" XP_024944493.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015608367.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_015607854.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_024944883.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_024947122.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015586576.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024936484.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_024940734.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015603046.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024946920.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015595546.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015596482.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_024939802.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_024946909.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015587397.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015600408.1 4 KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14 "Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism" XP_015606757.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_024938840.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_024946349.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_024944355.1 24 Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-202040 "Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G-protein activation" XP_015596420.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024939175.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024942106.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024939954.1 10 KEGG: 00650+2.3.3.10;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-7571;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781 "Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression" XP_015602244.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015601019.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015598000.1 9 Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603 "TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"UCH proteinases" XP_024940723.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_024947003.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_024943697.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_015588998.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_024936376.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024945835.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_015586137.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015589895.1 4 Reactome: R-HSA-446193;KEGG: 00311+1.21.3.1;MetaCyc: PWY-5629;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Penicillin and cephalosporin biosynthesis";"Isopenicillin N biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_015592730.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_015608306.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024935899.1 14 Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942 "Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)" XP_015595123.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024944101.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015590851.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_015602354.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015589083.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_024943113.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024942025.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024942192.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015591421.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015602550.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_015587157.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015594000.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024938831.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015594366.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_024943750.1 7 MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25 "Starch degradation V";"Glycogen degradation II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism" XP_015595297.1 6 KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;MetaCyc: PWY-5269;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Synthesis of PG";"Synthesis of PA" XP_024946590.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015598667.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation" XP_024945965.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015584926.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_024941958.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_015587068.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015591093.1 182 Reactome: R-HSA-9637628;Reactome: R-HSA-6782135;Reactome: R-HSA-8948751;Reactome: R-HSA-9613829;Reactome: R-HSA-5689901;Reactome: R-HSA-5676590;Reactome: R-HSA-5696394;Reactome: R-HSA-5656121;Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-983168;Reactome: R-HSA-72702;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-2559582;Reactome: R-HSA-6804757;Reactome: R-HSA-937072;Reactome: R-HSA-6783310;Reactome: R-HSA-6804760;Reactome: R-HSA-977225;Reactome: R-HSA-168638;Reactome: R-HSA-5656169;Reactome: R-HSA-382556;Reactome: R-HSA-937039;Reactome: R-HSA-174084;Reactome: R-HSA-8849469;Reactome: R-HSA-5668541;Reactome: R-HSA-8876493;Reactome: R-HSA-8939902;Reactome: R-HSA-2122947;Reactome: R-HSA-174154;Reactome: R-HSA-156827;Reactome: R-HSA-9646399;Reactome: R-HSA-8875360;Reactome: R-HSA-110314;Reactome: R-HSA-5654733;Reactome: R-HSA-1253288;Reactome: R-HSA-182971;Reactome: R-HSA-2408557;Reactome: R-HSA-5696397;Reactome: R-HSA-162588;Reactome: R-HSA-69541;Reactome: R-HSA-9010553;Reactome: R-HSA-937041;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-2672351;Reactome: R-HSA-975956;Reactome: R-HSA-8948747;Reactome: R-HSA-5689877;Reactome: R-HSA-917937;Reactome: R-HSA-187577;Reactome: R-HSA-8866652;Reactome: R-HSA-5696400;Reactome: R-HSA-3769402;Reactome: R-HSA-5675221;Reactome: R-HSA-912631;Reactome: R-HSA-975144;Reactome: R-HSA-2644606;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-174048;Reactome: R-HSA-72649;Reactome: R-HSA-901032;Reactome: R-HSA-9014325;Reactome: R-HSA-5610780;Reactome: R-HSA-9645460;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5675482;Reactome: R-HSA-211733;Reactome: R-HSA-205043;Reactome: R-HSA-8866654;Reactome: R-HSA-936964;Reactome: R-HSA-975163;Reactome: R-HSA-6781823;Reactome: R-HSA-450321;Reactome: R-HSA-110312;Reactome: R-HSA-2173791;Reactome: R-HSA-3322077;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-175474;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-5684264;Reactome: R-HSA-69481;Reactome: R-HSA-5685942;Reactome: R-HSA-5357905;Reactome: R-HSA-9633012;Reactome: R-HSA-3785653;Reactome: R-HSA-5693565;Reactome: R-HSA-1295596;Reactome: R-HSA-5655862;Reactome: R-HSA-5689603;Reactome: R-HSA-450302;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-179409;Reactome: R-HSA-180585;Reactome: R-HSA-936440;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-156902;Reactome: R-HSA-201681;Reactome: R-HSA-6804756;Reactome: R-HSA-168928;Reactome: R-HSA-975110;Reactome: R-HSA-8856828;Reactome: R-HSA-174184;Reactome: R-HSA-5205685;Reactome: R-HSA-937042;Reactome: R-HSA-2173795;Reactome: R-HSA-5362768;Reactome: R-HSA-209560;Reactome: R-HSA-2173788;Reactome: R-HSA-8941858;Reactome: R-HSA-209543;Reactome: R-HSA-5687128;Reactome: R-HSA-9013973;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-4641263;Reactome: R-HSA-69231;Reactome: R-HSA-2894862;Reactome: R-HSA-445989;Reactome: R-HSA-6781827;Reactome: R-HSA-174490;Reactome: R-HSA-3134975;Reactome: R-HSA-5654727;Reactome: R-HSA-8856825;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-5689896;Reactome: R-HSA-110320;Reactome: R-HSA-1236974;Reactome: R-HSA-9013507;Reactome: R-HSA-1799339;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-192823;Reactome: R-HSA-9636383;Reactome: R-HSA-8852276;Reactome: R-HSA-5654732;Reactome: R-HSA-1169408;Reactome: R-HSA-5696395;Reactome: R-HSA-8863795;Reactome: R-HSA-9033241;Reactome: R-HSA-2559580;Reactome: R-HSA-2979096;Reactome: R-HSA-975957;Reactome: R-HSA-4641258;Reactome: R-HSA-2122948;Reactome: R-HSA-2173796;Reactome: R-HSA-168927;Reactome: R-HSA-450408;Reactome: R-HSA-72764;Reactome: R-HSA-174178;Reactome: R-HSA-9615710;Reactome: R-HSA-6782210;Reactome: R-HSA-69017;Reactome: R-HSA-2691232;Reactome: R-HSA-1358803;Reactome: R-HSA-72706;Reactome: R-HSA-5658442;Reactome: R-HSA-5693607;Reactome: R-HSA-1236382;Reactome: R-HSA-2559585;Reactome: R-HSA-2871837;Reactome: R-HSA-6791226;Reactome: R-HSA-532668;Reactome: R-HSA-5654726;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-72689;Reactome: R-HSA-5689880;Reactome: R-HSA-72695 "Modulation by Mtb of host immune system";"Dual incision in TC-NER";"Regulation of PTEN stability and activity";"Chaperone Mediated Autophagy";"Metalloprotease DUBs";"NIK-->noncanonical NF-kB signaling";"DNA Damage Recognition in GG-NER";"Translesion synthesis by POLI";"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"Antigen processing: Ubiquitination & Proteasome degradation";"Ribosomal scanning and start codon recognition";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of TP53 Degradation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Methylation";"Amyloid fiber formation";"NOD1/2 Signaling Pathway";"Termination of translesion DNA synthesis";"ABC-family proteins mediated transport";"IRAK1 recruits IKK complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"TNFR2 non-canonical NF-kB pathway";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of RUNX2 expression and activity";"NOTCH1 Intracellular Domain Regulates Transcription";"APC/C:Cdc20 mediated degradation of Securin";"L13a-mediated translational silencing of Ceruloplasmin expression";"Aggrephagy";"InlB-mediated entry of Listeria monocytogenes into host cell";"Recognition of DNA damage by PCNA-containing replication complex";"Negative regulation of FGFR4 signaling";"Downregulation of ERBB4 signaling";"EGFR downregulation";"Selenocysteine synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Budding and maturation of HIV virion";"Stabilization of p53";"Regulation of expression of SLITs and ROBOs";"IKK complex recruitment mediated by RIP1";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Stimuli-sensing channels";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of PTEN localization";"Josephin domain DUBs";"Iron uptake and transport";"SCF(Skp2)-mediated degradation of p27/p21";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual Incision in GG-NER";"Deactivation of the beta-catenin transactivating complex";"Negative regulation of MAPK pathway";"Regulation of signaling by CBL";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Translation initiation complex formation";"ER Quality Control Compartment (ERQC)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Degradation of GLI1 by the proteasome";"Alpha-protein kinase 1 signaling pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of necroptotic cell death";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NRIF signals cell death from the nucleus";"E3 ubiquitin ligases ubiquitinate target proteins";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Formation of TC-NER Pre-Incision Complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Translesion synthesis by REV1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Glycogen synthesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Assembly Of The HIV Virion";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"G2/M Checkpoints";"HDR through Homologous Recombination (HRR)";"Regulation of TNFR1 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Myoclonic epilepsy of Lafora";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Spry regulation of FGF signaling";"Translesion synthesis by POLK";"UCH proteinases";"activated TAK1 mediates p38 MAPK activation";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"APC-Cdc20 mediated degradation of Nek2A";"Vif-mediated degradation of APOBEC3G";"Negative regulators of DDX58/IFIH1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Peptide chain elongation";"TCF dependent signaling in response to WNT";"Regulation of TP53 Activity through Phosphorylation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Clathrin-mediated endocytosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Pink/Parkin Mediated Mitophagy";"IRAK2 mediated activation of TAK1 complex";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NF-kB is activated and signals survival";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX3 expression and activity";"p75NTR recruits signalling complexes";"MAPK6/MAPK4 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of FZD by ubiquitination";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Membrane binding and targetting of GAG proteins";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of FGFR2 signaling";"Cargo recognition for clathrin-mediated endocytosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ovarian tumor domain proteases";"Translesion Synthesis by POLH";"ER-Phagosome pathway";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"SRP-dependent cotranslational protein targeting to membrane";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"Viral mRNA Translation";"Prevention of phagosomal-lysosomal fusion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of FGFR3 signaling";"ISG15 antiviral mechanism";"Formation of Incision Complex in GG-NER";"Downregulation of ERBB2 signaling";"Peroxisomal protein import";"Oxidative Stress Induced Senescence";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Degradation of DVL";"Activated NOTCH1 Transmits Signal to the Nucleus";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TICAM1, RIP1-mediated IKK complex recruitment";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Eukaryotic Translation Termination";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Late endosomal microautophagy";"Gap-filling DNA repair synthesis and ligation in TC-NER";"CDK-mediated phosphorylation and removal of Cdc6";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Downregulation of ERBB2:ERBB3 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of RAS by GAPs";"Processing of DNA double-strand break ends";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Oncogene Induced Senescence";"FCERI mediated NF-kB activation";"Major pathway of rRNA processing in the nucleolus and cytosol";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of FGFR1 signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Formation of a pool of free 40S subunits";"Ub-specific processing proteases";"Formation of the ternary complex, and subsequently, the 43S complex" XP_024945873.1 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" XP_024940372.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015608603.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015608577.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024935830.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015586266.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024943124.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015591159.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_024945188.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_015608582.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015598666.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_015603323.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_024941617.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_015594367.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_024940158.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015606098.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_015587683.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis" XP_015598080.1 12 KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527 "Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis";"Starch and sucrose metabolism";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Stachyose degradation" XP_015585168.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_024935825.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015598751.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation" XP_015599666.1 19 Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-432142 "Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Chylomicron clearance";"Chylomicron assembly";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"VLDL assembly";"LDL clearance";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL" XP_015605748.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_015603424.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_015607386.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_024942286.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_024941268.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015588166.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015600355.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015591160.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_015603892.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015600485.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015586019.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015588727.1 4 KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_015600432.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015588565.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400 "TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer" XP_024939385.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015603727.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024946586.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_015608447.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015589177.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_015601801.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015596064.1 14 Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;Reactome: R-HSA-434316;MetaCyc: PWY-6351;Reactome: R-HSA-500657;MetaCyc: PWY-6367;Reactome: R-HSA-112043;Reactome: R-HSA-399997;MetaCyc: PWY-7039;Reactome: R-HSA-418217;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11 "Ca2+ pathway";"Phosphatidylinositol signaling system";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Presynaptic function of Kainate receptors";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"G beta:gamma signalling through PLC beta";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism" XP_024947537.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_015595779.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_024938999.1 8 Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_015587393.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence" XP_024944320.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_015588709.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015585216.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_024944923.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_015592380.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_024939326.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_015601202.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024941661.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015587596.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_024946291.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015610526.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015587509.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_015608317.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024939716.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015585737.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015604894.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015596528.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_024940583.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_024938833.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015602805.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015610225.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_015588539.1 9 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015588107.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015606186.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_024941613.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_024936381.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015600139.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_015603552.1 5 Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000 "Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"RAF activation" XP_015602700.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015596803.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015604869.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024937795.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024941131.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_024943175.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_015596973.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757 "VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation" XP_024938357.1 4 MetaCyc: PWY-4361;Reactome: R-HSA-72731;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_015610237.1 6 MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_015597073.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024944115.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015603352.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024942840.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015594219.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015600901.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_015587903.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_015601690.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015603919.1 8 MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-2301;KEGG: 00521+5.5.1.4 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Streptomycin biosynthesis" XP_024940431.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015591826.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015603422.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_024939005.1 17 KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383 "Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Methane metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_024943776.1 11 Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670 "Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway" XP_015594698.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024939748.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015585135.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024938496.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949 "Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA" XP_015598757.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle" XP_015586673.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015606097.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_015598589.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024940585.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_015608744.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015592610.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024945470.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015587698.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015593733.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_024937225.1 10 MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Galactose metabolism" XP_024939717.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_024938837.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024939791.1 5 Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5649702 "Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_015586348.1 7 MetaCyc: PWY-7807;MetaCyc: PWY-6610;MetaCyc: PWY-6605;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7805;KEGG: 00230+2.4.2.7 "Glyphosate degradation III";"Adenine salvage";"Adenine and adenosine salvage II";"Neutrophil degranulation";"Purine salvage";"(aminomethyl)phosphonate degradation";"Purine metabolism" XP_015607544.1 8 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-165054 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA" XP_015599121.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_024936132.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015591909.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_024937772.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015596297.1 10 Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828 "Ub-specific processing proteases";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis" XP_024942158.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_024941547.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_024942026.1 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification" XP_024947394.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015610255.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_015592483.1 10 MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-6317 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)" XP_015608035.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015590426.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_024940955.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330 "Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_024940441.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_015609407.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015589478.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877 "HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase" XP_015602751.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024942632.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015587276.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_015588645.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_024940907.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024938258.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_024943172.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_024940442.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_015597714.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015600774.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_024947729.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015592256.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015609114.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_015608326.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015593365.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_024939329.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015608149.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_024946883.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_015584959.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_024940584.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_015586919.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168325 "tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis" XP_024940349.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607672.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-389957 "Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_015606869.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_024941934.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024944665.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_024940176.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_024942141.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024945245.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015599435.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_015597332.1 14 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion" XP_015597161.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_015607283.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015588786.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_015590450.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015585050.1 5 Reactome: R-HSA-389661;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046;KEGG: 00640+1.2.4.4 "Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism" XP_024937384.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015606482.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015597359.1 11 KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-6992;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-3881;Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-3861 "Fructose and mannose metabolism";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II" XP_015591537.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015601408.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_024944111.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015588471.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_015604053.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015601765.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_024941577.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024944234.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015602683.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_015608154.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_024945622.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015590076.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015592382.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024939019.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015587192.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015590991.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_024942159.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_015599544.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_015599165.1 12 MetaCyc: PWY-601;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-6936;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240 "Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Tryptophan metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Tryptophan catabolism" XP_015601352.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_015608677.1 18 KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00400+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1 "Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism" XP_015602248.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015606823.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015594338.1 12 Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606 "Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015597064.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024936565.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015602263.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015603174.1 44 Reactome: R-HSA-112409;Reactome: R-HSA-9635465;Reactome: R-HSA-3371453;Reactome: R-HSA-8939211;Reactome: R-HSA-6811558;Reactome: R-HSA-5663213;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9634638;Reactome: R-HSA-879415;Reactome: R-HSA-74749;Reactome: R-HSA-170968;Reactome: R-HSA-9627069;Reactome: R-HSA-6802955;Reactome: R-HSA-5654727;Reactome: R-HSA-5654726;Reactome: R-HSA-162658;Reactome: R-HSA-2559585;Reactome: R-HSA-6802952;Reactome: R-HSA-2029482;Reactome: R-HSA-202670;Reactome: R-HSA-1295596;Reactome: R-HSA-5654733;Reactome: R-HSA-198753;Reactome: R-HSA-2871796;Reactome: R-HSA-5674135;Reactome: R-HSA-444257;Reactome: R-HSA-445144;Reactome: R-HSA-8940973;Reactome: R-HSA-456926;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-982772;Reactome: R-HSA-375165;Reactome: R-HSA-5674499;Reactome: R-HSA-9649948;Reactome: R-HSA-881907;Reactome: R-HSA-2559580;Reactome: R-HSA-5668599;Reactome: R-HSA-5654732;Reactome: R-HSA-5675221;Reactome: R-HSA-6802948;Reactome: R-HSA-2559582;Reactome: R-HSA-8943724 "RAF-independent MAPK1/3 activation";"Suppression of apoptosis";"Regulation of HSF1-mediated heat shock response";"ESR-mediated signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate WASPs and WAVEs";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Advanced glycosylation endproduct receptor signaling";"Signal attenuation";"Frs2-mediated activation";"Regulation of the apoptosome activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR1 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Oncogene Induced Senescence";"Signaling by BRAF and RAF fusions";"Regulation of actin dynamics for phagocytic cup formation";"ERKs are inactivated";"Spry regulation of FGF signaling";"Negative regulation of FGFR4 signaling";"ERK/MAPK targets";"FCERI mediated MAPK activation";"MAP2K and MAPK activation";"RSK activation";"Signal transduction by L1";"RUNX2 regulates osteoblast differentiation";"Thrombin signalling through proteinase activated receptors (PARs)";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Growth hormone receptor signaling";"NCAM signaling for neurite out-growth";"Negative feedback regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Gastrin-CREB signalling pathway via PKC and MAPK";"Oxidative Stress Induced Senescence";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR3 signaling";"Negative regulation of MAPK pathway";"Signaling by high-kinase activity BRAF mutants";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of PTEN gene transcription" XP_024947071.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9 "Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_015590848.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_024938727.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024936491.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024937348.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015598032.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_024939285.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015601574.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024947481.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_024941484.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015592585.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015604826.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015599768.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015591151.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024938897.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_024944322.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_015597415.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015601671.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_015607942.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_015592129.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024943584.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015601768.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_024937043.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_024944891.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015592828.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015590955.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015602972.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024936127.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_015590914.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015605441.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_024946600.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024936049.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015603641.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024938422.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_024947089.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_015591965.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_015593834.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015604371.1 13 MetaCyc: PWY-7112;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1 "4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes";"Glutathione conjugation";"Gliotoxin biosynthesis";"Ascorbate and aldarate metabolism";"Glutathione metabolism" XP_015592098.1 25 Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-380270;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483 "EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins";"Recruitment of mitotic centrosome proteins and complexes";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs" XP_024945429.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015589227.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024947370.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015593268.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_024946934.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015606448.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170 "Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_024944043.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015586100.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_024942768.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024941796.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_024937702.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_015608782.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024945751.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015603418.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024940987.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015595735.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015586825.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_015605578.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_024937950.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024937324.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264 "Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging" XP_015585211.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015602797.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015598199.2 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_015586985.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_015598725.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_024947027.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024936740.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024936797.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015597310.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015605015.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024937236.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_024940375.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015607249.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_015606166.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-8951664;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation";"rRNA modification in the nucleus and cytosol" XP_024938825.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_015587317.1 2 Reactome: R-HSA-201681;Reactome: R-HSA-3772470 "TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists" XP_015603967.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_024945169.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_015602098.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015600123.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_024947398.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015591449.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_024941834.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_015607982.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024938997.1 8 KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9617324 "Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_015589717.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015598182.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_015600874.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_015609959.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024937349.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015607737.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015595771.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024944880.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015598733.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_015610269.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_024939004.1 17 KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37 "Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism" XP_015601350.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_024940505.1 11 Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302 "p38MAPK events";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation" XP_024940995.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_024942598.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_024939266.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024936436.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660 "PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway" XP_015594866.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_015589978.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015586470.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_015604305.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024941070.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_024941614.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_024947865.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_015601232.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_015600352.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015592763.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs" XP_015588887.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015605091.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_024943194.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_024942760.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" XP_015600481.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015586907.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015605375.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015606953.1 4 KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9 "Propanoate metabolism";"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import";"beta-Alanine metabolism" XP_015588845.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_015591761.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015596917.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_015585738.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015606477.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015587831.1 5 MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_015604767.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024946897.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_015600892.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024940332.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024939172.1 7 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;Reactome: R-HSA-351202 "Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_015587874.2 7 MetaCyc: PWY-46;MetaCyc: PWY-31;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984;Reactome: R-HSA-70635 "Putrescine biosynthesis III";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism";"Urea cycle";"Urea cycle" XP_024937766.1 17 Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-163765;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-2426168 "Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"Jadomycin biosynthesis";"Propanoate metabolism";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_024937224.1 10 Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385 "Glycolysis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)" XP_015601708.1 5 Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111469;Reactome: R-HSA-9627069 "Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response";"Regulation of the apoptosome activity" XP_015590939.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015604876.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015607764.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_015587090.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_015607286.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015587275.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_015608368.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024945278.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_015600767.2 13 MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_015593890.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_015605941.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-983170 "Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_015597704.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024947360.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024936879.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis" XP_015584704.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015599438.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024942839.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015586001.1 18 MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4 "Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism" XP_015601814.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_024946573.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015594740.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015610585.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015584859.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024937414.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024939704.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015607204.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_024941899.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015600156.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015586892.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism" XP_015592456.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_024946884.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_015585308.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_015598146.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_015604564.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015592579.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_015608810.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015604056.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015597539.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation" XP_024944339.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015610258.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_015596833.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015584930.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_015605002.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_015602849.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015606617.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841 "Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines" XP_015589606.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_015591538.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_024941061.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015607025.1 11 Reactome: R-HSA-2559582;Reactome: R-HSA-8943724;Reactome: R-HSA-8862803;Reactome: R-HSA-1912408;Reactome: R-HSA-450341;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580 "Senescence-Associated Secretory Phenotype (SASP)";"Regulation of PTEN gene transcription";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Pre-NOTCH Transcription and Translation";"Activation of the AP-1 family of transcription factors";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence" XP_015602542.1 19 Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497 "Chylomicron assembly";"Chylomicron clearance";"Retinoid metabolism and transport";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL remodeling";"LDL clearance";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"VLDL clearance";"VLDL assembly";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors" XP_024940182.1 9 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_015593851.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015585674.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015592485.1 10 MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation" XP_015606286.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015603679.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024937357.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015602525.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events" XP_024946367.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015585382.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_015600773.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_015593634.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015606866.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015596921.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_015592646.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione-mediated detoxification I" XP_015602952.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015597705.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015604698.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015589425.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_024946348.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_015586875.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015585839.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015609230.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024935507.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_024938675.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_024944208.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_015609389.1 14 MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-181;MetaCyc: PWY-2201;MetaCyc: PWY-1622;Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1 "Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Cyanoamino acid metabolism";"Purine nucleobases degradation II (anaerobic)";"Photorespiration ";"Folate transformations I";"Formaldehyde assimilation I (serine pathway)";"Metabolism of folate and pterines";"Folate polyglutamylation";"One carbon pool by folate";"Glycine betaine degradation II (mammalian)";"Methane metabolism" XP_024942162.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_015600566.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024944205.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024943176.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_015593866.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_015603206.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation" XP_024940665.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_024938053.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024937637.1 9 Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_024938259.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_024936850.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_015586956.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_015595344.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015607157.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015599450.1 5 KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660499 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane" XP_015598436.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024943272.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015596575.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_024938820.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_015586590.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_015609580.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_024939050.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015588792.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_015609962.1 11 Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169 "DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis" XP_015610524.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015608652.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015597511.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015601471.1 4 MetaCyc: PWY-6129;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199 "Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_024938590.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_015605443.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_015592970.1 5 Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702 "Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_015589091.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015605299.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015607469.1 4 Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015584830.1 4 Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607 "Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Ub-specific processing proteases";"Processing of DNA double-strand break ends" XP_015595676.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_024938832.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024947871.1 2 Reactome: R-HSA-419771;Reactome: R-HSA-8951664 "Opsins";"Neddylation" XP_015595159.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_024944405.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024944888.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015598557.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015600776.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015605448.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_015607219.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015604819.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_015588849.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_024944930.1 5 Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148 "Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024944594.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_015584975.1 8 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)" XP_015595787.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_015606382.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015603502.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015602068.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_015602814.1 19 Reactome: R-HSA-8964616;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-418885;Reactome: R-HSA-5663213;Reactome: R-HSA-389359;Reactome: R-HSA-428543;Reactome: R-HSA-8950505;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-114604 "G beta:gamma signalling through CDC42";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"DCC mediated attractive signaling";"RHO GTPases Activate WASPs and WAVEs";"CD28 dependent Vav1 pathway";"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate Formins";"Myogenesis";"MAPK6/MAPK4 signaling";"EGFR downregulation";"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"GPVI-mediated activation cascade" XP_015600270.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_024940966.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_024939054.1 10 Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;MetaCyc: PWY-7979;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;MetaCyc: PWY-7661;Reactome: R-HSA-162699;MetaCyc: PWY-7921;KEGG: 00510+2.4.1.83;Reactome: R-HSA-913709 "Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein N-glycosylation (Haloferax volcanii)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation I (yeast)";"N-Glycan biosynthesis";"O-linked glycosylation of mucins" XP_024937842.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_024936971.1 22 Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-4641262 "T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"RAF activation";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_024937287.1 7 KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897 "Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes" XP_015595367.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015595424.1 25 Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-381771;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-420092 "G alpha (z) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors" XP_015605344.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015599428.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_015603926.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024943225.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_015589405.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_015606659.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_015584678.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015596709.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_015594545.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024937361.1 5 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_024939383.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015601445.1 5 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway" XP_024939552.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_015593259.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024938912.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_024938848.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_024940119.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_024938013.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway" XP_015597509.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_015608332.1 13 MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_015602792.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024943119.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015593470.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024943055.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_015602710.1 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562 "Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria" XP_015607073.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015601204.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_015604169.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024935840.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_015588790.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_024947427.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_015596966.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764 "ABC-family proteins mediated transport";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling" XP_024935808.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_015595364.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015608494.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024935958.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_015595078.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_015601406.1 3 MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661 "Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis" XP_015608081.1 1 Reactome: R-HSA-419771 "Opsins" XP_015599071.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024940204.1 5 MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2 "Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis" XP_015589465.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase" XP_015601047.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_024937787.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015599564.1 5 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Formation of apoptosome" XP_015608485.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_015595621.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_015602675.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015601190.1 4 KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_024938146.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024940059.1 14 MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-3781 "Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)" XP_024939743.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015599887.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015603709.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_024941586.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015591432.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015605382.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_015584717.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_024947065.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_024940350.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015598566.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015584914.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015598629.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015607218.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_024945438.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024939470.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_024943936.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_015600272.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-113507 "Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation" XP_015609768.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_015602990.1 6 KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-6898;MetaCyc: PWY-7356;MetaCyc: PWY-6907 "Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)" XP_015599472.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_015603182.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-7854 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" XP_015586304.1 13 Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015590257.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_015593016.1 19 KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;Reactome: R-HSA-70263;Reactome: R-HSA-71403;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37 "Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Gluconeogenesis";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism" XP_024946267.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760 "Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation" XP_015600818.1 15 Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_015602629.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_015605958.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_024937952.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015600905.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_015596907.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796 "mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation" XP_015594743.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015587396.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024945338.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395 "Fanconi Anemia Pathway";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER" XP_024946814.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_024947258.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024944509.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_024945518.1 6 Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18 "Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism" XP_024947432.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_024939072.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_024941256.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015600583.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_015588646.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_024947403.1 42 Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847 "Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Packaging Of Telomere Ends";"Amyloid fiber formation";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"Meiotic synapsis";"HDACs deacetylate histones";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"HATs acetylate histones" XP_024938225.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-877300 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion homeostasis";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Interferon gamma signaling" XP_024946959.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015607405.1 22 MetaCyc: PWY-5514;MetaCyc: PWY-3801;MetaCyc: PWY-8013;MetaCyc: PWY-5659;MetaCyc: PWY-7385;Reactome: R-HSA-6798695;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-5384;Reactome: R-HSA-70263;MetaCyc: PWY-6981;KEGG: 00500+5.3.1.9;Reactome: R-HSA-5628897;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-5054;MetaCyc: PWY-622;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"GDP-mannose biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Neutrophil degranulation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis";"1,5-anhydrofructose degradation";"Sucrose degradation IV (sucrose phosphorylase)";"Gluconeogenesis";"Chitin biosynthesis";"Starch and sucrose metabolism";"TP53 Regulates Metabolic Genes";"Pentose phosphate pathway";"Sucrose biosynthesis III";"D-sorbitol biosynthesis I";"Starch biosynthesis";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism" XP_015604601.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015609195.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015590087.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_015602977.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024939720.1 4 Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-2586552 "Prolactin receptor signaling";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin" XP_015585337.1 10 KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8055 "Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis" XP_024938872.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015585767.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_015607680.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015602624.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813 "Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids" XP_024945893.1 16 Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-1963640;Reactome: R-HSA-1257604;Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631 "PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"GRB2 events in ERBB2 signaling";"PIP3 activates AKT signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility" XP_015595038.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015593961.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition" XP_015599889.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_024942818.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024940377.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015607957.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015604490.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015609972.1 14 Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_024946502.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015598657.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015593370.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015603724.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015604509.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015596906.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341 "FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors" XP_024939388.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015609489.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015594218.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_015586149.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_015598294.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015592790.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_015585615.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_024937354.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_015599149.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015597229.1 33 Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-168271 "Mitotic Prometaphase";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"snRNP Assembly";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus" XP_015592194.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015590805.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015591646.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_024940069.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins" XP_015603817.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6277 "Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_015608738.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024941637.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_024946860.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-428540 "Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Activation of RAC1" XP_024939319.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024944558.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024947480.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_024938031.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-3232142 "Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of ubiquitinylation proteins" XP_015609874.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024941020.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_024936723.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015593489.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015600934.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015589175.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_015584876.2 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_015606559.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024938336.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_015600333.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015595352.1 13 Reactome: R-HSA-5362768;Reactome: R-HSA-5689877;Reactome: R-HSA-6798695;Reactome: R-HSA-3371511;Reactome: R-HSA-5358346;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-8876725;Reactome: R-HSA-5689896;Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-382556 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Josephin domain DUBs";"Neutrophil degranulation";"HSF1 activation";"Hedgehog ligand biogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Protein methylation";"Ovarian tumor domain proteases";"Defective CFTR causes cystic fibrosis";"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport" XP_024946366.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015597543.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955 "Neutrophil degranulation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_024938447.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_015588761.1 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" XP_015604297.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" XP_015603865.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_024944559.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015610296.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_024936077.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015588184.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024937953.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015587449.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015603566.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015598228.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_015600008.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_024944695.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_015597751.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024944082.1 33 Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-180910 "SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs" XP_015603218.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_015599072.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015599952.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_015602533.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_024943886.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015599946.1 6 Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis" XP_015603022.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_015600806.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024943404.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_015593090.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_015608784.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024942328.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015596812.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_024946963.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015587379.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_024944383.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024941920.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_015598293.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015587343.1 12 MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708;MetaCyc: PWY-5873 "Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)" XP_024937961.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024937562.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_015600330.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024944347.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024941354.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015588583.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" XP_015584970.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_024938200.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_015602534.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_024946268.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015588288.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015591086.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress" XP_015601600.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_024947149.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015588702.1 14 MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-181;MetaCyc: PWY-2201;MetaCyc: PWY-1622 "Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Methane metabolism";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Photorespiration ";"Folate transformations I";"Formaldehyde assimilation I (serine pathway)" XP_024947028.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024945457.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015603969.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_024938362.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_015586616.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_015589640.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015598810.1 11 Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)" XP_024940621.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015591542.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_024946403.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015584896.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024943349.1 4 KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963 "Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I" XP_024940496.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015590492.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_015609956.1 13 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928663;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"RHO GTPases Activate ROCKs";"Human papillomavirus infection";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse";"PI3K-Akt signaling pathway";"Thermogenesis" XP_015604579.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024940500.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015608295.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015603504.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015589303.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024939703.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015594254.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_015593397.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205 "Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription" XP_024944354.1 24 Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-381676 "Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_024940952.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_015607134.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_015591169.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_015607401.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_015606689.1 11 Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631 "RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility" XP_024936286.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015600807.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024946128.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015599336.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_024936542.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_015605729.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_024945836.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_015593148.1 18 KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409 "Ether lipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_015599209.1 3 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_015596802.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607504.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_015598062.1 12 Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817 "Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Stachyose degradation";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015588671.1 57 Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276 "TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_015584992.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1" XP_015602425.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015597218.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015593724.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy" XP_015594870.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_015597331.1 11 MetaCyc: PWY-3881;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-6992;MetaCyc: PWY-7456;MetaCyc: PWY-7586;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8 "Mannitol biosynthesis";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism" XP_024947799.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015586918.1 27 Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-168276 "Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways" XP_015606281.1 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation" XP_015603073.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015600396.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015598761.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_015589417.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_024939760.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015592130.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_015609037.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015591918.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024937561.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_015606188.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_015590672.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024937343.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_024936173.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015606904.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_015602854.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-442720 "Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"PKA activation in glucagon signalling";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_015596441.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096 "A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"HS-GAG degradation" XP_015602959.1 7 Reactome: R-HSA-9033241;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;Reactome: R-HSA-77111 "Peroxisomal protein import";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Butanoate metabolism";"Geraniol degradation";"Synthesis of Ketone Bodies" XP_015609475.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015600002.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015607014.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_024943058.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_024941023.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_015596454.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015601400.1 22 MetaCyc: PWY-5659;MetaCyc: PWY-3801;MetaCyc: PWY-8013;MetaCyc: PWY-5514;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-6142;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5384;MetaCyc: PWY-6992;Reactome: R-HSA-5628897;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6981;Reactome: R-HSA-70263;MetaCyc: PWY-622;MetaCyc: PWY-5054;MetaCyc: PWY-7347;KEGG: 00030+5.3.1.9;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9 "GDP-mannose biosynthesis";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis II";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Neutrophil degranulation";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis";"Sucrose degradation IV (sucrose phosphorylase)";"1,5-anhydrofructose degradation";"TP53 Regulates Metabolic Genes";"Starch and sucrose metabolism";"Chitin biosynthesis";"Gluconeogenesis";"Starch biosynthesis";"D-sorbitol biosynthesis I";"Sucrose biosynthesis III";"Pentose phosphate pathway";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism" XP_015592266.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_024940237.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024937108.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015602586.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_024947255.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015591061.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015607506.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024941401.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015609966.1 8 MetaCyc: PWY-7979;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633 "Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_024937118.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_024945068.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" XP_024942758.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024942470.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015605094.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_024944080.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_015593509.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015599752.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_015605293.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_024936352.1 19 MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-70263;Reactome: R-HSA-71403;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37 "Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Citric acid cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)" XP_015598050.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_015597663.1 13 Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101 "Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation" XP_015600055.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_024946164.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_024936016.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_024944336.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024946143.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_024937109.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015595863.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_015588851.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_015595858.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_024940853.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024939377.1 26 Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids" XP_015588176.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015588109.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024937463.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024945091.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_024940994.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_015605811.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_015588809.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015584957.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_015604476.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis" XP_024936619.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015585773.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015605227.1 10 KEGG: 05170+2.7.11.1;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5357905;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"T cell receptor signaling pathway";"Regulation of TNFR1 signaling";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_024945619.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015590707.1 13 KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7709 "Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis" XP_024941076.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_015597709.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015587516.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015586613.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_024937818.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015600955.1 3 Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833 "ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)" XP_015592128.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015592607.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015591225.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_015584753.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_015585257.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_024935783.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015591355.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015592602.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024943653.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024944919.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015606131.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_024937113.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-5607761 "FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling" XP_015597010.1 3 Reactome: R-HSA-5576893;Reactome: R-HSA-5576890;Reactome: R-HSA-1296072 "Phase 2 - plateau phase";"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels" XP_015585047.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024941253.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015599082.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_015610381.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase" XP_015594467.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015586612.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_015604069.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Photosynthesis";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Ion channel transport" XP_024943121.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015586093.1 13 Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-6842;MetaCyc: PWY-2261;Reactome: R-HSA-196836;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18 "Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450" XP_015598571.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015607004.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_024941941.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015595052.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015601549.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736 "The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors" XP_015594976.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_015605826.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_015587765.1 31 MetaCyc: PWY-8049;MetaCyc: PWY-8047;MetaCyc: PWY-7663;MetaCyc: PWY-5366;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5971;MetaCyc: PWY-5142;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;MetaCyc: PWY-5367;MetaCyc: PWY-8012;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-6799;MetaCyc: PWY-5147;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-7664;MetaCyc: PWY-7723;MetaCyc: PWYG-321;MetaCyc: PWY-6113;MetaCyc: PWY-5989;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-7858 "Pederin biosynthesis";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Biotin metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Petroselinate biosynthesis";"Mupirocin biosynthesis";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis I (plants)";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II" XP_015596791.1 20 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-176187 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress" YP_002889387.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_015604364.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024943202.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015588983.1 13 MetaCyc: PWY-6545;KEGG: 00230+3.6.1.66;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7821;MetaCyc: PWY-7184;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00770+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Pantothenate and CoA biosynthesis" XP_024938323.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015600780.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676 "Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle" XP_015586419.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_015595646.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic" XP_015598628.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015607620.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165181 "Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB" XP_015608320.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015587872.1 13 Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392 "Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II" XP_024938938.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_015586303.1 13 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674135 "Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway";"Signaling by BRAF and RAF fusions";"Human immunodeficiency virus 1 infection";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Human papillomavirus infection";"MAP2K and MAPK activation" XP_015598656.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015595837.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_024942621.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_015599074.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015604440.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_015586602.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015591766.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015594091.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_015604632.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015603506.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015603335.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015590209.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015605048.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015599285.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015597072.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015605827.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024938210.1 19 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692 "Ion homeostasis";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity" XP_015591198.1 11 MetaCyc: PWY-7391;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7560;KEGG: 00900+5.3.3.2;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-191273;MetaCyc: PWY-5123;MetaCyc: PWY-7524;MetaCyc: PWY-6383 "Isoprene biosynthesis II (engineered)";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway III (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" XP_015586678.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024940856.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024941859.1 10 KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23 "Other glycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Galactose metabolism";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_024947259.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024944241.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015586651.1 9 Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-69205;Reactome: R-HSA-68962 "Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription";"Activation of the pre-replicative complex" XP_024938170.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic" XP_015604287.1 5 Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310 "Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway" XP_015587853.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_015604705.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015597918.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364 "RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_015599090.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015607345.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_015600022.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015592593.1 17 Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69601;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-75035 "Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"Thermogenesis";"Activation of ATR in response to replication stress";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_015600688.1 3 KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347 "Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" XP_015603231.1 4 KEGG: 00500+3.1.3.9;KEGG: 00052+3.1.3.9;KEGG: 00010+3.1.3.9;Reactome: R-HSA-70263 "Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis" XP_015586677.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024938361.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015609507.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015600886.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_015599244.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_024945683.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015587873.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587 "Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)" XP_015603781.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import" XP_015609667.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485 "Effects of PIP2 hydrolysis";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis" XP_024936119.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024940981.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_015585204.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015585099.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015601785.2 2 MetaCyc: PWY-6502;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins" XP_024937565.1 14 MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-975634;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4 "Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism" XP_015599394.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024940067.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events" XP_024937247.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_024941511.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015603900.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_015593002.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024941314.1 10 Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_015591290.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015607428.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_024945382.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015586473.1 7 MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522 "Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism" XP_015585792.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_015591480.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_024945625.1 10 Reactome: R-HSA-1660499;KEGG: 04150+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;MetaCyc: PWY-6352;KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 04151+2.7.1.153 "Synthesis of PIPs at the plasma membrane";"mTOR signaling pathway";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"3-phosphoinositide biosynthesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_024941483.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024936185.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015609668.1 13 Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509 "Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling" XP_024942165.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_015597037.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_024943651.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_024935975.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015594578.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015585049.1 11 Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2122948 "Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_024941936.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015597245.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport" XP_015589549.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024937270.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_024940984.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_015593887.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_024936498.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024940535.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024944243.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling" XP_015606305.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_015595760.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_015604060.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024938274.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015586007.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_024943698.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015595427.1 2 Reactome: R-HSA-110329;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_015597196.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015589989.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_015596746.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-8934903 "Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Receptor Mediated Mitophagy" XP_015585727.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_024947205.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024942147.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024938702.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015602725.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015592974.1 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1 "Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism" XP_024945637.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024942201.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015599131.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015598724.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015594378.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015585507.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015584766.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015607567.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024935597.1 13 Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928663;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1 "Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection" XP_015591227.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_024938206.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001 "Ion transport by P-type ATPases";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade" XP_024944047.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015587310.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015600107.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_024944237.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015584825.1 7 Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71403 "Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)" XP_015591157.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_024945038.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015592896.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015605949.1 16 Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-1257604;Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986 "SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"PIP3 activates AKT signaling";"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2" XP_015594834.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015600875.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_024937288.1 7 Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2 "TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism" XP_015590298.1 3 MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996 "Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)" XP_015586710.1 3 KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857 "Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis" XP_015603874.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015598927.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_024942455.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015603553.1 5 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"RAF activation";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants" XP_024947233.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_015586870.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958 "Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_015605175.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015594654.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015598251.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015607951.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_024942712.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015585828.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024940939.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024935878.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_024940177.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" XP_015585338.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15 "Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_024943101.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024944342.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024940347.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024945260.1 21 KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7219;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7224 "Purine metabolism";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Thiamine metabolism";"Drug metabolism - other enzymes";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Purine deoxyribonucleosides salvage" XP_024946907.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015602608.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024945317.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015587316.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015591241.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015597307.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015598675.1 6 MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12 "Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis" XP_015586895.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_024946965.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015599879.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015591048.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015598562.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_024941355.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015603520.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination" XP_024937082.1 6 Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015604595.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015596814.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" XP_015599322.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_024941400.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015598948.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_024943013.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_015600357.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024944988.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_015603955.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_015591188.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015586309.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1362277 "Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex" XP_024944601.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024938224.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade" XP_015610266.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024946950.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024940331.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015594992.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024941980.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation" XP_015604357.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015607625.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015604687.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_015604664.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015585573.1 5 MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" XP_015595301.1 8 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_015604415.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167246 "Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_015600994.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_015589550.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015605306.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015601777.1 33 Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-1169408 "HCMV Late Events";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism" XP_015600666.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis" XP_024935963.1 6 Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-2029485;Reactome: R-HSA-418597;Reactome: R-HSA-114508 "DAG and IP3 signaling";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis" XP_024943351.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_015587061.1 10 MetaCyc: PWY-4661;MetaCyc: PWY-6366;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855204;MetaCyc: PWY-6362;MetaCyc: PWY-6365;Reactome: R-HSA-983231;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6554;Reactome: R-HSA-1855167 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol" XP_024942717.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_015607289.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_024938058.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015585007.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015595341.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015604529.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015605560.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015585502.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024946641.1 8 Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_024936270.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015594647.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_024940671.1 5 Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-198323 "mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol" XP_015598716.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation" XP_015600009.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_024939624.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_015606212.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024941024.1 2 KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" YP_002889383.1 7 Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083;MetaCyc: PWY-4302 "Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Complex I biogenesis";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration III (alternative oxidase pathway)" XP_015601459.1 22 MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6958;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7728;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7049;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7726;MetaCyc: PWY-7725;MetaCyc: PWY-7727;MetaCyc: PWY-7035;MetaCyc: PWY-6433 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Fatty acid elongation";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_015601382.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015601122.1 33 Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142 "tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins" XP_015606273.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024942932.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015609536.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024946620.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024942389.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024938222.1 19 Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors" XP_015596183.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_015604359.1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" XP_024940361.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_024936493.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024942234.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_024944776.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_024940990.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_024936109.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_015595407.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015594779.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024941885.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015586597.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-400206 "Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha" XP_015604519.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015609172.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_024940060.1 14 KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-6728 "Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle" XP_024939082.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_015599189.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_024940978.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_024944929.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024937101.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015604831.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_024938664.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024941548.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_015594869.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_015590878.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-163615 "Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"PKA activation" XP_024942374.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_015598922.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024946611.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_015602027.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_015589565.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_015585560.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015598580.1 6 KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23 "Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation" XP_015587169.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_015607282.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024944467.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_015609963.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024944463.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015590684.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_015590519.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_015603958.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015586627.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015593064.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_024943998.1 6 KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Galactose metabolism" XP_015604849.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_015593026.1 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282 "Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B" XP_024938957.1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_015604059.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024944892.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024938457.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_015601494.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015610336.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015587166.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024942837.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024947586.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_015595562.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_015588653.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024937622.1 57 Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764 "Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling" XP_015609280.1 42 Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847 "Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of DNA double-strand break ends";"HCMV Late Events";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Amyloid fiber formation";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"Meiotic synapsis";"HDACs deacetylate histones";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"HATs acetylate histones" XP_015587277.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015594539.1 11 Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-171007 "activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"p38MAPK events" XP_015598994.1 4 KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation" XP_024938098.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015598208.1 5 MetaCyc: PWY-4983;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39 "Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism" XP_015586254.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015599393.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024936893.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_015610074.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015607654.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" XP_024946626.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_015594969.1 6 KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22 "Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism" XP_024944489.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_024939694.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_024940815.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_024941163.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_024937246.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_024944611.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_015610263.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_024946364.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015595305.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015606220.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015607571.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015589445.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_024945372.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015604715.2 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6 "Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism" XP_015610116.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_024945632.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_024946370.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015598117.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_024944984.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_015598924.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024940466.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015601594.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015601843.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_015604513.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015605229.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015585754.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024944236.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015595499.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015595254.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_024942512.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015586247.1 4 KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260 "N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_024935605.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015601789.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024940920.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015595307.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015608050.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015594118.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_024936070.1 4 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing" XP_015598163.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015602433.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_024936328.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_015597013.1 3 Reactome: R-HSA-1296072;Reactome: R-HSA-5576890;Reactome: R-HSA-5576893 "Voltage gated Potassium channels";"Phase 3 - rapid repolarisation";"Phase 2 - plateau phase" XP_024935581.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015610335.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024939805.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_015604594.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024937524.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_015599537.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_024945520.1 6 MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1 "Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism" XP_024940825.1 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_015605537.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015610113.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015594664.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015594212.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159231 "SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_024943205.1 5 KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-3841 "One carbon pool by folate";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)" XP_015607838.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015589172.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-532668 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_015598002.1 9 Reactome: R-HSA-5689603;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788 "UCH proteinases";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_015607487.1 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes" XP_015602687.1 4 Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;Reactome: R-HSA-4719377 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_024939876.1 18 MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG" XP_015594952.2 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_015598542.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024942633.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015592672.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015605126.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015600062.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_015607205.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_015590957.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_024936734.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159231 "SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_024937211.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_015591780.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" XP_015603542.1 4 MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662 "Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_024946958.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024937351.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024937855.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024941605.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_024942392.1 4 Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015602194.1 17 KEGG: 04714+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-174178;Reactome: R-HSA-9022692;Reactome: R-HSA-68877;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 05163+2.7.11.1 "Thermogenesis";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of MECP2 expression and activity";"Mitotic Prometaphase";"Relaxin signaling pathway";"EML4 and NUDC in mitotic spindle formation";"Human cytomegalovirus infection" XP_015606272.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_024942607.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015601118.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_015603003.1 7 MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817 "Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis" XP_015589182.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane" XP_015600824.1 15 Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565 "HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015602355.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_024941093.1 17 Reactome: R-HSA-1169091;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-202424;Reactome: R-HSA-4086398 "Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling";"Ca2+ pathway" XP_015602585.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_015592613.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_024940416.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_015599757.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_024940514.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015585591.1 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_015585678.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015603970.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015598001.1 9 Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases" XP_024942107.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015598352.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_015609383.1 7 KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;MetaCyc: PWY-6614 "One carbon pool by folate";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis" XP_015586501.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015595446.1 18 Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-8051 "Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Acyl chain remodelling of PC";"Anandamide biosynthesis I" XP_015601862.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015603430.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015606479.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024939324.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_015592429.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015586141.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015602192.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_024942355.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024941887.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_024940722.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015590812.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024938459.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015586558.1 12 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-749476 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation" XP_015594353.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015588182.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015594741.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024942542.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_015597279.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_015598448.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015606301.1 5 Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)" XP_015594046.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_015599636.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024938428.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_024940093.1 18 Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;MetaCyc: PWY-7511;Reactome: R-HSA-6796648;Reactome: R-HSA-5689901;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Protein ubiquitination";"TP53 Regulates Transcription of DNA Repair Genes";"Metalloprotease DUBs";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" XP_015600941.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015585569.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024945812.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015585682.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024939049.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015598221.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024941508.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015587408.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015594332.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_015589327.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024943381.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024942711.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015596772.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_024941017.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_024938176.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_024946827.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_015597986.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628 "O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_015610519.1 4 Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_024937151.1 4 KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642 "Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation" XP_024946736.1 4 Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026 "Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)" XP_015602705.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024937250.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024938868.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_015610529.1 57 Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541 "Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"UCH proteinases";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway" XP_024946983.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015607921.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_015609940.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015586849.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_015609288.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_015609238.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015590961.1 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_015597872.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656 "Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry" XP_015597065.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015587627.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_015605963.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024935790.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015586705.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_024938665.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015609528.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015585131.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_015605177.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015588641.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_024937570.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015605996.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-6784531 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus" XP_024946581.1 10 Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-7344 "Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis" XP_015585339.1 10 KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8055 "Glycerolipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis" XP_015587656.1 13 MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation" XP_024947546.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_015591308.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015606821.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024943553.1 16 Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-975155;Reactome: R-HSA-975871;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-1810476;Reactome: R-HSA-9020702;Reactome: R-HSA-1257604;Reactome: R-HSA-975138;Reactome: R-HSA-5602680;Reactome: R-HSA-1236974;Reactome: R-HSA-6811558;Reactome: R-HSA-5603037 "MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 dependent cascade initiated on endosome";"MyD88 cascade initiated on plasma membrane";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"RIP-mediated NFkB activation via ZBP1";"Interleukin-1 signaling";"PIP3 activates AKT signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR5)";"ER-Phagosome pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR5)" XP_015608293.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015598113.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_024943742.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015590208.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024943042.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_015603644.1 5 Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471 "VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Downstream signal transduction";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_024941718.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015596811.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_024940991.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_024941795.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015593835.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_024938801.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015603850.1 5 KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22 "Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism" XP_015597217.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015605383.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_015590246.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015604282.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_015594538.2 11 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097 "Human papillomavirus infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"p38MAPK events";"PI3K-Akt signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway" XP_015609466.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015594511.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_015584813.1 8 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_024938869.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_024939382.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015600489.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_015585436.1 10 KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11 "Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism" XP_015595774.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015596437.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024944591.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_015593604.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_015599335.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015600658.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_024943054.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015597545.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6798695 "MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Neutrophil degranulation" XP_015607794.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_015603324.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015596931.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_024943938.1 20 MetaCyc: PWY-7221;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7224;Reactome: R-HSA-380270;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;Reactome: R-HSA-380320;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7227 "Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Recruitment of NuMA to mitotic centrosomes";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_015592835.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_024940686.1 6 KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820 "Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)" XP_024944202.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_015585046.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024935688.1 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_024941646.1 3 Reactome: R-HSA-5576893;Reactome: R-HSA-5576890;Reactome: R-HSA-1296072 "Phase 2 - plateau phase";"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels" XP_024937875.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_015598565.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015591731.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_024944238.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015609182.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015589181.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_024947434.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_024936680.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_015609245.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_024941490.1 5 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_024936321.1 19 Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938 "Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"LDL clearance";"VLDL assembly";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"VLDL clearance";"Retinoid metabolism and transport";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Chylomicron assembly";"Chylomicron clearance";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand" XP_015586620.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024942116.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024947673.1 6 MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259 "Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Purine catabolism" XP_015600269.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689 "Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_024939865.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_015591156.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_015597720.1 4 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines" XP_015586730.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_015586008.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_015594394.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_015603191.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015599653.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015608625.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015599258.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Circadian Clock";"RMTs methylate histone arginines";"RORA activates gene expression" XP_024941645.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015607288.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024937615.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015594247.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_015607870.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_015586452.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_024946578.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_024941319.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015588834.1 17 MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2 "Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism";"Fatty acid biosynthesis";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Propanoate metabolism" XP_024938448.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_024936555.1 12 Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "G alpha (12/13) signalling events";"Human papillomavirus infection";"Human cytomegalovirus infection";"G alpha (q) signalling events";"Rho GTPase cycle";"Relaxin signaling pathway";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_024942673.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_024941884.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_024943462.1 14 MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6538;KEGG: 00230+1.17.1.4+1.17.3.2;KEGG: 00232+1.17.3.2;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;MetaCyc: PWY-6607;Reactome: R-HSA-8851680;Reactome: R-HSA-74259;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-6999 "Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Purine metabolism";"Caffeine metabolism";"Purine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Purine catabolism";"Drug metabolism - other enzymes";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Theophylline degradation" XP_015594921.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015599104.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_024938941.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_024940369.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_015610020.1 6 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway" XP_015599713.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024944159.1 12 KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4 "Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism" XP_024936032.1 25 Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-380270;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436 "The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Recruitment of mitotic centrosome proteins and complexes";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic" XP_024936350.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024938302.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015593635.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015587331.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015610444.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043 "G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events" XP_015609713.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211981 "Endogenous sterols";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Xenobiotics" XP_024937791.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_024942428.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015598280.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_015601101.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024936347.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015605001.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_015607850.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015600405.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015585576.1 7 Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606 "Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_024944590.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_015599042.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_015587238.1 14 MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-75109 "Plasmalogen biosynthesis";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Triglyceride biosynthesis" XP_015591052.1 5 Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5358346 "ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hedgehog ligand biogenesis" XP_024946066.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015590007.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-3232142;Reactome: R-HSA-983168 "Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SUMOylation of ubiquitinylation proteins";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015591561.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015599769.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015604809.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024945842.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_024945516.1 6 MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;Reactome: R-HSA-189085 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate" XP_015600763.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_015595411.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_024940179.1 27 KEGG: 04150+2.7.11.1;Reactome: R-HSA-399956;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5467340;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-3371453;Reactome: R-HSA-5250924;Reactome: R-HSA-198323;Reactome: R-HSA-5358751;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4641262;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5610783;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-5467337 "mTOR signaling pathway";"CRMPs in Sema3A signaling";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"AXIN missense mutants destabilize the destruction complex";"Human cytomegalovirus infection";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Regulation of HSF1-mediated heat shock response";"B-WICH complex positively regulates rRNA expression";"AKT phosphorylates targets in the cytosol";"S45 mutants of beta-catenin aren't phosphorylated";"Relaxin signaling pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Thermogenesis";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human papillomavirus infection";"Degradation of GLI2 by the proteasome";"Human immunodeficiency virus 1 infection";"Regulation of RUNX2 expression and activity";"APC truncation mutants have impaired AXIN binding" XP_024939043.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015593091.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015592150.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024942200.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_024946804.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_024937456.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_024943110.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015596128.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015610120.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024940386.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_024941514.1 10 Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897 "Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes" XP_024936197.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015599276.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_015603017.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024935915.1 4 MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494 "Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism";"Choline degradation IV" XP_015609384.1 5 Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841 "Metabolism of folate and pterines";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate transformations II (plants)" XP_015591309.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_024943486.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_015605173.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015596810.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_015598791.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_024938916.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015598345.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_015597222.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015601491.1 3 Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Glutathione metabolism" XP_024942118.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015590398.1 26 Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483 "MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs" XP_015602747.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024937338.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015605716.1 33 Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-180910 "Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"snRNP Assembly";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs" XP_015602055.1 56 Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168 "TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015601050.1 8 KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" XP_015604916.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_015607001.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_024943850.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024945960.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015597540.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695 "Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation" XP_024947679.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015599284.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024943506.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024938211.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244 "Signaling by BRAF and RAF fusions";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ion homeostasis";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation" XP_024940787.1 8 MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism" XP_015608017.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024939819.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_024936904.1 5 Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency" XP_015585413.1 18 Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes" XP_015594399.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_015588802.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_024936639.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_024941670.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_015594657.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015589635.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813 "Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids" XP_015599084.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_015600659.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015597031.1 5 Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007 "NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"mTOR signaling pathway";"p38MAPK events" XP_015591249.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015596059.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024946294.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_024938699.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015598607.1 24 Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-4086398;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Ca2+ pathway";"Glucagon-type ligand receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (s) signalling events";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_024944305.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015592560.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_024945912.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_024939815.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015584828.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_015588467.1 7 Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798 "Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Hedgehog 'on' state";"Activation of SMO";"Release of Hh-Np from the secreting cell" XP_024942120.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015609849.1 3 MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57 "Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism" XP_015593260.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_015607864.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041 "Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis" XP_024936988.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015593735.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015604058.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024947138.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_024945765.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_024935531.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015586916.1 6 Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-201722 "RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex" XP_015608765.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015584693.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_015597682.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_015592137.1 6 MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6922;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539 "L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_015589612.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955 "Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Ion homeostasis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_015589002.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024943345.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_024936238.1 8 KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Glycolysis";"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism" XP_024935827.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015586726.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_024945242.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015607027.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_015590706.1 13 MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-7141 "Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis" XP_024936901.1 5 Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency" XP_024943994.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015589021.1 4 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis" XP_024936331.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015592161.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_024943372.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015587774.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015600595.1 13 Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-8964038 "Recycling pathway of L1";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"LDL clearance" XP_015610377.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase" XP_015592177.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-202433 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules" XP_015585666.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015604846.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_024937231.1 10 KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11 "Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Galactose metabolism" XP_015596641.1 3 Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320 "Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH" XP_024947397.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024938591.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_024943844.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015602968.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_015605874.1 11 Reactome: R-HSA-5218900;Reactome: R-HSA-69416;Reactome: R-HSA-3371378;Reactome: R-HSA-75157;Reactome: R-HSA-9013957;Reactome: R-HSA-5213460;Reactome: R-HSA-140534;Reactome: R-HSA-933543;Reactome: R-HSA-75158;Reactome: R-HSA-5357786;Reactome: R-HSA-2562578 "CASP8 activity is inhibited";"Dimerization of procaspase-8";"Regulation by c-FLIP";"FasL/ CD95L signaling";"TLR3-mediated TICAM1-dependent programmed cell death";"RIPK1-mediated regulated necrosis";"Caspase activation via Death Receptors in the presence of ligand";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TRAIL signaling";"TNFR1-induced proapoptotic signaling";"TRIF-mediated programmed cell death" XP_015606215.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_015608242.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_024941248.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015599083.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_024937333.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024943778.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1 "G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state";"Purine metabolism" XP_015596568.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024936798.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015600213.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015610320.1 5 Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_015607925.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_024941895.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015604191.1 9 KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation" XP_015593897.1 18 Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5689901;Reactome: R-HSA-6796648;Reactome: R-HSA-5693568;MetaCyc: PWY-7511 "Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Metalloprotease DUBs";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Protein ubiquitination" XP_015587952.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015605196.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015585614.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_015598963.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_024941892.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015608989.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015590824.1 83 Reactome: R-HSA-74751;Reactome: R-HSA-6811558;Reactome: R-HSA-5654700;Reactome: R-HSA-210993;Reactome: R-HSA-5663213;Reactome: R-HSA-8875555;Reactome: R-HSA-167044;Reactome: R-HSA-5654699;Reactome: R-HSA-74749;Reactome: R-HSA-388841;Reactome: R-HSA-186763;Reactome: R-HSA-1433559;Reactome: R-HSA-5654727;Reactome: R-HSA-9028731;Reactome: R-HSA-8853334;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-5654733;Reactome: R-HSA-8875360;Reactome: R-HSA-512988;Reactome: R-HSA-9664565;Reactome: R-HSA-2871809;Reactome: R-HSA-391160;Reactome: R-HSA-9634285;Reactome: R-HSA-1250196;Reactome: R-HSA-8851907;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-109704;Reactome: R-HSA-8853659;Reactome: R-HSA-5655291;Reactome: R-HSA-5655253;Reactome: R-HSA-1250347;Reactome: R-HSA-389359;Reactome: R-HSA-5673001;Reactome: R-HSA-8865999;Reactome: R-HSA-983695;Reactome: R-HSA-354194;Reactome: R-HSA-8853338;Reactome: R-HSA-1236382;Reactome: R-HSA-5654689;Reactome: R-HSA-2179392;Reactome: R-HSA-112412;Reactome: R-HSA-180292;Reactome: R-HSA-9028335;Reactome: R-HSA-5654726;Reactome: R-HSA-5654693;Reactome: R-HSA-9645135;Reactome: R-HSA-5637810;Reactome: R-HSA-5654712;Reactome: R-HSA-180336;Reactome: R-HSA-5654719;Reactome: R-HSA-1295596;Reactome: R-HSA-8851805;Reactome: R-HSA-2730905;Reactome: R-HSA-2029482;Reactome: R-HSA-5654695;Reactome: R-HSA-2424491;Reactome: R-HSA-5655302;Reactome: R-HSA-9026519;Reactome: R-HSA-2871796;Reactome: R-HSA-8875656;Reactome: R-HSA-5654704;Reactome: R-HSA-1433557;Reactome: R-HSA-8983432;Reactome: R-HSA-5654688;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-375165;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-5654710;Reactome: R-HSA-5654732;Reactome: R-HSA-5654706;Reactome: R-HSA-9034864;Reactome: R-HSA-9027284;Reactome: R-HSA-179812;Reactome: R-HSA-2428933;Reactome: R-HSA-9607240;Reactome: R-HSA-5654720;Reactome: R-HSA-1839117 "Insulin receptor signalling cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FRS-mediated FGFR2 signaling";"Tie2 Signaling";"RHO GTPases Activate WASPs and WAVEs";"MET activates RAP1 and RAC1";"Signalling to RAS";"SHC-mediated cascade:FGFR2";"Signal attenuation";"Costimulation by the CD28 family";"Downstream signal transduction";"Regulation of KIT signaling";"Negative regulation of FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"Signaling by FGFR3 fusions in cancer";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of FGFR4 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signaling by ERBB2 KD Mutants";"FCERI mediated Ca+2 mobilization";"Signal regulatory protein family interactions";"Constitutive Signaling by Overexpressed ERBB2";"SHC1 events in ERBB2 signaling";"MET activates PI3K/AKT signaling";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"PI3K Cascade";"RET signaling";"Signaling by FGFR4 in disease";"Signaling by FGFR2 in disease";"SHC1 events in ERBB4 signaling";"CD28 dependent Vav1 pathway";"RAF/MAP kinase cascade";"MET activates PTPN11";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signaling by FGFR3 point mutants in cancer";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI-3K cascade:FGFR1";"EGFR Transactivation by Gastrin";"SOS-mediated signalling";"GAB1 signalosome";"Activated NTRK2 signals through PI3K";"Negative regulation of FGFR1 signaling";"FRS-mediated FGFR1 signaling";"STAT5 Activation";"Constitutive Signaling by EGFRvIII";"FRS-mediated FGFR4 signaling";"SHC1 events in EGFR signaling";"SHC-mediated cascade:FGFR4";"Spry regulation of FGF signaling";"MET activates RAS signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of actin dynamics for phagocytic cup formation";"PI-3K cascade:FGFR2";"DAP12 signaling";"Signaling by FGFR1 in disease";"Activated NTRK2 signals through RAS";"FCERI mediated MAPK activation";"MET receptor recycling";"SHC-mediated cascade:FGFR3";"Signaling by SCF-KIT";"Interleukin-15 signaling";"SHC-mediated cascade:FGFR1";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"NCAM signaling for neurite out-growth";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"PI-3K cascade:FGFR3";"Negative regulation of FGFR3 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK3 signals through RAS";"Erythropoietin activates RAS";"GRB2 events in EGFR signaling";"SHC-related events triggered by IGF1R";"FLT3 Signaling";"PI-3K cascade:FGFR4";"Signaling by cytosolic FGFR1 fusion mutants" XP_015599290.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_024947703.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway" XP_015599771.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015595516.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_015594342.1 13 MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_024940419.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_015593515.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_015605071.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_024947059.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024938595.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015608937.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015609129.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024941106.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024946772.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015585414.1 18 Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery" XP_024944694.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_015600947.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_015596583.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015592136.1 6 MetaCyc: PWY-6344;MetaCyc: PWY-6922;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13 "L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_015594080.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_024943494.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024942276.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_024940604.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024937103.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024939169.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024935874.1 6 Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606 "Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_024938205.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948 "Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Ion homeostasis";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants" XP_015607851.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_024937935.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015599656.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024942716.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_015598983.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_015602438.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_024938674.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_015601075.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024946120.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_015599439.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015594846.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024944240.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_024940398.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015586871.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958 "Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_024947753.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024939880.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_015599348.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_015604273.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_024944588.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015595875.2 3 Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_015607158.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015589166.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691 "T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling" XP_015608633.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024935484.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_015586418.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_024945035.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015606430.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_015597402.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_015587241.1 14 MetaCyc: PWY-6453;Reactome: R-HSA-75109;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4 "Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Plasmalogen biosynthesis";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism" XP_015597201.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015589937.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015592919.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552 "Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin" XP_024937274.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015609861.1 3 KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_015593882.1 6 Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_024940374.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_024939455.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024938851.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015592367.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015596721.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA" XP_015591076.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015602100.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015591558.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015588575.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation" XP_015588135.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024944998.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_024943748.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015589055.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_015610474.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_015586686.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" XP_015584681.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_015605272.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024941943.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015609860.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_015597598.1 12 MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5872 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)" XP_015610180.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015593331.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-381183 "Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes" XP_015609756.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_015602961.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_015594694.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015590764.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" XP_024946266.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718 "Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes" XP_024937285.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500 "Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle" XP_015595049.1 10 Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408 "NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation" XP_024936136.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024946771.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024944016.1 10 Reactome: R-HSA-5689880;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1 "Ub-specific processing proteases";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"HATs acetylate histones";"Human immunodeficiency virus 1 infection" XP_015602623.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015599478.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_024943751.1 6 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-416993;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network" XP_015603378.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015588949.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_015584854.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015585667.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024938917.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024939039.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015602798.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015607277.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015600819.1 15 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_015589189.1 24 KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-2871837;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-202424;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-354192;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218921 "Thermogenesis";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"FCERI mediated NF-kB activation";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Downstream TCR signaling";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Activation of AKT2";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Integrin signaling";"RSK activation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"VEGFR2 mediated cell proliferation" XP_015586238.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_015589646.1 11 Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1 "Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway" XP_015595125.1 7 Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-983231 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production" XP_015594456.1 4 MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I" XP_015585262.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_024939178.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_024937826.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015602937.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015584690.1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-7117 "Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_015590269.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024944605.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_015601049.1 8 Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;MetaCyc: PWY-6174 "PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)" XP_024944506.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_015588698.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652 "Regulation of PTEN localization";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_024936641.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_015585673.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015594477.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015605013.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024937385.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_024939609.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015586851.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015595431.1 2 Reactome: R-HSA-110328;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine" XP_024937701.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015595881.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_015601850.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015587538.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_024941797.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_015592427.1 11 MetaCyc: PWY-5675;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6964;Reactome: R-HSA-210455 "Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism" XP_015606135.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015596295.1 10 Reactome: R-HSA-9636383;Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-432720 "Prevention of phagosomal-lysosomal fusion";"Ub-specific processing proteases";"Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Lysosome Vesicle Biogenesis" XP_024943178.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_015607197.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_015594368.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_015605355.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015604535.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024937022.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_015588337.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015586725.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_015607486.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_015606147.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" XP_015592124.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_024945089.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_015585588.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_024937771.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015599880.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015599500.1 57 Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236 "SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_015588281.1 5 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_015587365.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_024943298.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015598558.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024937433.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379 "ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"HCMV Late Events" XP_015609476.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015597713.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_024936695.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024937020.1 8 Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"HCMV Early Events";"Regulation of PTEN gene transcription" XP_015594520.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_024946109.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015591559.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015592857.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_024945782.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_024941891.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024936681.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_015600356.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024946655.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_015606464.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024944174.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_024936685.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_024936945.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015602041.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation" XP_015588083.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024942193.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_015607463.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015607195.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_015597219.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015590935.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_015586767.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015603155.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024936506.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024940909.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024943453.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_015591016.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-983170 "Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_024936477.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_024935885.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_024940028.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015597029.1 5 Reactome: R-HSA-168638;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-171007 "NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"DSCAM interactions";"p38MAPK events" XP_024939714.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024936073.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_024941893.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024946568.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015592192.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024947723.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_015588536.1 9 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"PI3K-Akt signaling pathway" XP_015591438.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Purine metabolism" XP_024937277.1 9 Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-110314 "Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex" XP_024947506.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_024939783.1 12 MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis" XP_024944363.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015593958.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1362277 "Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex" XP_015607175.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024947232.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_015604015.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_015605198.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015594406.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_024943009.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015602013.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015589719.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_024945389.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015608057.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015585261.1 25 Reactome: R-HSA-380270;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189 "Recruitment of mitotic centrosome proteins and complexes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins" XP_015588358.1 3 KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_024937454.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_024942199.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015589331.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015587358.1 4 Reactome: R-HSA-1971475;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26 "A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate" XP_024936015.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_024946430.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_024935834.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_024943127.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_015597557.1 7 Reactome: R-HSA-163210;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation";"Cristae formation";"Mitochondrial protein import" XP_015589567.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation" XP_015589115.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015604117.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015594463.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024944913.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_024936566.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015607105.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024946572.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015597919.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_015602057.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_015592786.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015590210.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015606300.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_024936019.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"