Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_034941392.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_034938459.1 10 MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042 "1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis IV (plant cytosol)" XP_034934405.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_034943055.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034940064.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_034950660.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034952051.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034937749.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_034944566.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation" XP_034952508.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_034951974.1 14 MetaCyc: PWY-5057;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5076;MetaCyc: PWY-5104;MetaCyc: PWY-7767;MetaCyc: PWY-5101 "L-valine degradation II";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation";"L-isoleucine degradation II";"L-leucine degradation III";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II" XP_034950456.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_034952005.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_034937501.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_034941498.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034949087.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_034943072.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034950924.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034943191.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034950279.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034942150.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034945806.1 57 Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8939236 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_034951544.1 8 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_034948654.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_034935205.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_034947055.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_034947765.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034949951.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949953.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_034949623.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034944177.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_034935403.1 3 Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation" XP_034943591.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034945966.1 14 MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis" XP_034950086.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_034938428.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_034934238.1 24 Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878 "Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"COPI-mediated anterograde transport" XP_034940963.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034937331.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957 "Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034950917.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_034949431.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Polymerase switching";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI" XP_034945451.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_034941021.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749 "Platelet sensitization by LDL";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated" XP_034935951.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_034946235.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_034952559.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034945279.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034950670.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_034942607.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events" XP_034939756.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_034944912.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034934381.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034935516.1 83 Reactome: R-HSA-167044;Reactome: R-HSA-9028731;Reactome: R-HSA-2871796;Reactome: R-HSA-8856828;Reactome: R-HSA-2219530;Reactome: R-HSA-8851805;Reactome: R-HSA-9026519;Reactome: R-HSA-186763;Reactome: R-HSA-512988;Reactome: R-HSA-8851907;Reactome: R-HSA-8875555;Reactome: R-HSA-1295596;Reactome: R-HSA-2428933;Reactome: R-HSA-8865999;Reactome: R-HSA-9034864;Reactome: R-HSA-912631;Reactome: R-HSA-5654693;Reactome: R-HSA-8875360;Reactome: R-HSA-8853659;Reactome: R-HSA-5654700;Reactome: R-HSA-2424491;Reactome: R-HSA-8853334;Reactome: R-HSA-5654720;Reactome: R-HSA-5654733;Reactome: R-HSA-5637810;Reactome: R-HSA-1963642;Reactome: R-HSA-1839117;Reactome: R-HSA-1433559;Reactome: R-HSA-180292;Reactome: R-HSA-74749;Reactome: R-HSA-6807004;Reactome: R-HSA-5654712;Reactome: R-HSA-5654719;Reactome: R-HSA-391160;Reactome: R-HSA-112412;Reactome: R-HSA-1250347;Reactome: R-HSA-1257604;Reactome: R-HSA-9027284;Reactome: R-HSA-2029482;Reactome: R-HSA-2179392;Reactome: R-HSA-5654732;Reactome: R-HSA-5655302;Reactome: R-HSA-2871809;Reactome: R-HSA-9634285;Reactome: R-HSA-389359;Reactome: R-HSA-9645135;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-5654727;Reactome: R-HSA-5654704;Reactome: R-HSA-5655253;Reactome: R-HSA-1963640;Reactome: R-HSA-388841;Reactome: R-HSA-182971;Reactome: R-HSA-180336;Reactome: R-HSA-354194;Reactome: R-HSA-2730905;Reactome: R-HSA-9607240;Reactome: R-HSA-1250196;Reactome: R-HSA-109704;Reactome: R-HSA-1236382;Reactome: R-HSA-5654726;Reactome: R-HSA-8983432;Reactome: R-HSA-375165;Reactome: R-HSA-1433557;Reactome: R-HSA-74751;Reactome: R-HSA-912526;Reactome: R-HSA-5654699;Reactome: R-HSA-210993;Reactome: R-HSA-5654689;Reactome: R-HSA-5655291;Reactome: R-HSA-983695;Reactome: R-HSA-5654695;Reactome: R-HSA-179812;Reactome: R-HSA-8853338;Reactome: R-HSA-5654710;Reactome: R-HSA-9028335;Reactome: R-HSA-5654688;Reactome: R-HSA-5654706;Reactome: R-HSA-6811558;Reactome: R-HSA-5663213;Reactome: R-HSA-8856825;Reactome: R-HSA-8875656 "Signalling to RAS";"Activated NTRK2 signals through FRS2 and FRS3";"FCERI mediated MAPK activation";"Clathrin-mediated endocytosis";"Constitutive Signaling by Aberrant PI3K in Cancer";"MET activates RAS signaling";"Activated NTRK2 signals through RAS";"Downstream signal transduction";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"MET activates PI3K/AKT signaling";"MET activates RAP1 and RAC1";"Spry regulation of FGF signaling";"SHC-related events triggered by IGF1R";"MET activates PTPN11";"Activated NTRK3 signals through RAS";"Regulation of signaling by CBL";"FRS-mediated FGFR1 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"RET signaling";"FRS-mediated FGFR2 signaling";"DAP12 signaling";"Signaling by FGFR3 fusions in cancer";"PI-3K cascade:FGFR4";"Negative regulation of FGFR4 signaling";"Constitutive Signaling by EGFRvIII";"PI3K events in ERBB2 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"Regulation of KIT signaling";"GAB1 signalosome";"Signal attenuation";"Negative regulation of MET activity";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR4";"Signal regulatory protein family interactions";"SOS-mediated signalling";"SHC1 events in ERBB4 signaling";"PIP3 activates AKT signaling";"Erythropoietin activates RAS";"Regulation of actin dynamics for phagocytic cup formation";"EGFR Transactivation by Gastrin";"Negative regulation of FGFR3 signaling";"Signaling by FGFR1 in disease";"FCERI mediated Ca+2 mobilization";"Constitutive Signaling by Overexpressed ERBB2";"CD28 dependent Vav1 pathway";"STAT5 Activation";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Negative regulation of FGFR2 signaling";"SHC-mediated cascade:FGFR3";"Signaling by FGFR2 in disease";"GRB2 events in ERBB2 signaling";"Costimulation by the CD28 family";"EGFR downregulation";"SHC1 events in EGFR signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Role of LAT2/NTAL/LAB on calcium mobilization";"FLT3 Signaling";"SHC1 events in ERBB2 signaling";"PI3K Cascade";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of FGFR1 signaling";"Interleukin-15 signaling";"NCAM signaling for neurite out-growth";"Signaling by SCF-KIT";"Insulin receptor signalling cascade";"Interleukin receptor SHC signaling";"SHC-mediated cascade:FGFR2";"Tie2 Signaling";"PI-3K cascade:FGFR1";"Signaling by FGFR4 in disease";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PI-3K cascade:FGFR2";"GRB2 events in EGFR signaling";"Signaling by FGFR3 point mutants in cancer";"PI-3K cascade:FGFR3";"Activated NTRK2 signals through PI3K";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR3 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate WASPs and WAVEs";"Cargo recognition for clathrin-mediated endocytosis";"MET receptor recycling" XP_034937396.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034945776.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034945222.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_034941482.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034943829.1 5 MetaCyc: PWY-6129;Reactome: R-HSA-193048;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94 "Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_034938316.1 8 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Thermogenesis" XP_034950604.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034947787.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034943322.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_034940918.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034936021.1 40 Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-674695;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955 "MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"HIV Transcription Initiation";"FGFR2 alternative splicing";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation" XP_034942204.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034948990.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_034934548.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-445144 "Synthesis of PC";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1" XP_034951847.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034934457.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034945968.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_034944587.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_034942829.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_034943485.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_034952626.1 10 MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-6901;Reactome: R-HSA-70263;MetaCyc: PWY-5484;Reactome: R-HSA-70171 "Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis" XP_034949156.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-3108214 "Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins" XP_034949813.1 9 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9620244 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation" XP_034938035.1 16 Reactome: R-HSA-5602498;Reactome: R-HSA-6811558;Reactome: R-HSA-1810476;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-975110;Reactome: R-HSA-975138;Reactome: R-HSA-209543;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-3134963;Reactome: R-HSA-5603037;Reactome: R-HSA-9020702;Reactome: R-HSA-5603041;Reactome: R-HSA-1236974;Reactome: R-HSA-975155 "MyD88 deficiency (TLR2/4)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RIP-mediated NFkB activation via ZBP1";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"p75NTR recruits signalling complexes";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR5)";"Interleukin-1 signaling";"IRAK4 deficiency (TLR2/4)";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome" XP_034934038.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034936099.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_034939362.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034942240.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation" XP_034934790.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_034946428.1 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism" XP_034935874.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_034951889.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_034952491.1 8 KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00010+1.1.1.27 "Cysteine and methionine metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycolysis / Gluconeogenesis" XP_034950804.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_034949706.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_034947066.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034938879.1 1 Reactome: R-HSA-156581 "Methylation" XP_034943279.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034942488.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_034950881.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034936045.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034939988.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034945705.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_034941980.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_034937653.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034939540.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_034941124.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_034937750.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_034946830.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034940556.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_034952212.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_034943800.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034940960.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034940508.1 5 MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism" XP_034939455.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_034946550.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034946957.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034936278.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034945851.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034943898.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034945972.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_034940352.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034951151.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization" XP_034952056.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034942611.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic" XP_034948462.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_034935373.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" XP_034949262.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034951606.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034948424.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_034933992.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034934566.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_034947518.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_034941994.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555 "G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events" XP_034943353.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_034938820.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_034941023.1 22 Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5467340 "Degradation of beta-catenin by the destruction complex";"RAF activation";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex" XP_034941837.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034950592.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_034946552.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_034947252.1 13 KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916 "Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"CS/DS degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Hyaluronan uptake and degradation" XP_034939453.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_034948589.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_034946531.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_034936068.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_034936865.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034947715.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034934277.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_034934469.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034943934.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_034949782.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_034935607.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034941184.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "Hedgehog 'off' state";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_034938458.1 10 MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11 "Glycolysis IV (plant cytosol)";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis";"Fructose and mannose metabolism" XP_034945787.1 7 KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363 "Inositol phosphate metabolism";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_034941322.1 13 MetaCyc: PWY-5497;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-2201;MetaCyc: PWY-6613;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-7909;KEGG: 00670+6.3.4.3 "Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate" XP_034935610.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_034945598.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034937737.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034939439.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_034939158.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_034946723.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_034940283.1 5 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3 "Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"Folate biosynthesis" XP_034933718.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_034937136.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034949962.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_034949632.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_034941034.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034936903.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034936723.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_034942483.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_034950631.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034937564.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034939775.1 5 Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614 "Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage" XP_034948107.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_034933844.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_034940349.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034944928.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034944244.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_034933725.1 4 MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688 "(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism" XP_034937787.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034947642.1 7 Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_034937382.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034950440.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_034937479.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_034942949.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034942262.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_034937258.1 19 Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-202733 "LDL clearance";"Scavenging by Class A Receptors";"VLDL clearance";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Chylomicron assembly";"VLDL assembly";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall" XP_034939620.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_034952129.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034947259.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034946137.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_034943000.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-4615885 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins" XP_034936330.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_034947176.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_034937993.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034944015.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361 "Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_034936201.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034934231.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_034952185.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034947126.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_034942615.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_034950075.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034947648.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034945667.1 9 KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00401+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00270+2.6.1.5 "Phenylalanine metabolism";"Tyrosine catabolism";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism" XP_034941455.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034950226.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_034941915.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257 "Protein ubiquitination";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Degradation of AXIN" XP_034937519.1 2 Reactome: R-HSA-352230;Reactome: R-HSA-442660 "Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters" XP_034949711.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_034945449.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_034948572.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034948728.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_034948666.1 8 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_034940888.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_034934497.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034952569.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034942018.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_034949978.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_034938975.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_034934347.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression" XP_034946144.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_034950240.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_034948173.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034946893.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_034935375.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" XP_034948332.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034949606.1 16 Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167287 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery" XP_034934134.1 6 MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-6608 "Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation II";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III" XP_034936358.1 6 KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36 "Inositol phosphate metabolism";"3-phosphoinositide degradation";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system" XP_034951501.1 5 MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_034935058.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034949261.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_034939130.1 16 Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408 "Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation" XP_034941998.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_034948368.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034935806.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034947102.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034947605.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034936521.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_034949081.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034940847.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_034947800.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_034948483.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription" XP_034942358.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034939660.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034943508.1 6 KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;Reactome: R-HSA-5083632 "Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" XP_034937135.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034941721.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034949820.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis" XP_034936547.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_034950907.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034933933.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034934404.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_034952100.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_034937989.1 10 KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-6536;Reactome: R-HSA-916853;KEGG: 00250+2.6.1.19;MetaCyc: PWY-4321 "Propanoate metabolism";"4-aminobutanoate degradation I";"Butanoate metabolism";"4-aminobutanoate degradation V";"beta-Alanine metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"Degradation of GABA";"Alanine, aspartate and glutamate metabolism";"L-glutamate degradation IV" XP_034950364.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034949704.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_034946805.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034945718.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs" XP_034945978.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_034939684.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_034950602.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034945789.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_034940825.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277 "Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex" XP_034946829.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034943619.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034950264.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_034942499.1 11 Reactome: R-HSA-3371378;Reactome: R-HSA-9013957;Reactome: R-HSA-2562578;Reactome: R-HSA-75158;Reactome: R-HSA-140534;Reactome: R-HSA-5213460;Reactome: R-HSA-69416;Reactome: R-HSA-75157;Reactome: R-HSA-5218900;Reactome: R-HSA-933543;Reactome: R-HSA-5357786 "Regulation by c-FLIP";"TLR3-mediated TICAM1-dependent programmed cell death";"TRIF-mediated programmed cell death";"TRAIL signaling";"Caspase activation via Death Receptors in the presence of ligand";"RIPK1-mediated regulated necrosis";"Dimerization of procaspase-8";"FasL/ CD95L signaling";"CASP8 activity is inhibited";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TNFR1-induced proapoptotic signaling" XP_034942730.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins" XP_034947970.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_034943111.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034948657.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034941649.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_034936763.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034938413.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_034939597.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034940906.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_034937088.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034950101.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_034947550.1 60 MetaCyc: PWY-6863;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00627+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-6946;MetaCyc: PWY-7007;MetaCyc: PWY-7778;MetaCyc: PWY-5136;Reactome: R-HSA-1482798;KEGG: 00623+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5177;MetaCyc: PWY-1361;Reactome: R-HSA-77288;MetaCyc: PWY-6945;Reactome: R-HSA-77350;Reactome: R-HSA-77348;Reactome: R-HSA-77346;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00650+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00062+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;Reactome: R-HSA-77305;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00362+4.2.1.17;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17 "Pyruvate fermentation to hexanol (engineered)";"Geraniol degradation";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol II (engineered)";"Lysine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Aminobenzoate degradation";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"Fermentation to 2-methylbutanoate";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Methyl ketone biosynthesis (engineered)";"2-methylpropene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Acyl chain remodeling of CL";"Toluene degradation";"Fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Benzoate degradation";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Caprolactam degradation";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"Butanoate metabolism";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid elongation";"Fatty acid elongation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Tryptophan metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"Benzoate degradation";"Tryptophan metabolism";"Fatty acid salvage";"Geraniol degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism" XP_034943716.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034942365.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs" XP_034939755.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_034947305.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034939972.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_034946126.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034933738.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_034942587.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034936237.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_034941914.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_034949339.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_034951927.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_034951756.1 5 Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253 "Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_034937703.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034949018.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034948009.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034947891.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034942613.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation" XP_034946497.1 10 MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-5826 "Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis" XP_034936079.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_034945739.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034951958.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_034934865.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_034946135.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_034938309.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_034947623.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034950535.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism" XP_034935482.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_034952578.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034937507.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034950206.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_034949915.1 10 MetaCyc: PWY-8051;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15 "Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism" XP_034948037.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034949722.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_034941056.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_034951055.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034951361.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034936082.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_034938876.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_034949268.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_034937911.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_034948340.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_034939943.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034951159.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_034937421.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72163 "snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_034938429.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5872;KEGG: 00130+1.14.99.60 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_034945959.1 14 MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)" XP_034950178.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_034948801.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_034934422.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_034950395.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_034952637.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034937652.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034943821.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034936114.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034934140.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_034944811.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034941926.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039 "Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex" XP_034945166.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034935838.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034946101.1 10 Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-983231 "Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production" XP_034951538.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_034952059.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034951742.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034944593.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034952076.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis" XP_034952357.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_034939039.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034935881.1 52 Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-76061;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-1834949;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167242 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_034951635.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034951566.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034948825.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579 "Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange" XP_034939992.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034948143.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034938824.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_034939724.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034950222.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034944653.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_034951621.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_034943358.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-163615 "G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation" XP_034949628.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_034947474.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_034945394.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034949942.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034946100.1 10 Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022538 "SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA" XP_034936152.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034939838.1 5 Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_034944353.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_034946159.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034948885.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034948665.1 8 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection" XP_034942228.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_034946739.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034946899.1 52 Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-5578749;Reactome: R-HSA-73980;Reactome: R-HSA-167161;Reactome: R-HSA-749476;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-6796648;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-674695 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Termination";"HIV Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Pre-transcription Events" XP_034936916.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034950370.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034948623.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034940905.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_034934549.1 10 Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243 "WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Synthesis of PC";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034933945.1 7 Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-212436;Reactome: R-HSA-2173796 "Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_034937649.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034946467.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Regulation of PTEN localization" XP_034936027.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_034940354.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034935745.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_034941949.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034952545.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_034938819.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_034951306.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034946325.1 30 Reactome: R-HSA-6804758;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198693;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-1358803;Reactome: R-HSA-8876198;Reactome: R-HSA-5628897;Reactome: R-HSA-199418;Reactome: R-HSA-111447;Reactome: R-HSA-69656;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-8948751;Reactome: R-HSA-211163;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804759;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-8941332;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-389513;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400 "Regulation of TP53 Activity through Acetylation";"mTOR signaling pathway";"AKT phosphorylates targets in the nucleus";"Human papillomavirus infection";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of ERBB2:ERBB3 signaling";"RAB GEFs exchange GTP for GDP on RABs";"TP53 Regulates Metabolic Genes";"Negative regulation of the PI3K/AKT network";"Activation of BAD and translocation to mitochondria";"Cyclin A:Cdk2-associated events at S phase entry";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Regulation of PTEN stability and activity";"AKT-mediated inactivation of FOXO1A";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Association with Co-factors";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"RUNX2 regulates genes involved in cell migration";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Cyclin E associated events during G1/S transition";"CTLA4 inhibitory signaling";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Regulation of localization of FOXO transcription factors";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer" XP_034943449.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034936145.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034945236.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034944736.1 8 Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-9627069 "Formation of apoptosome";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity" XP_034948303.1 5 Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation" XP_034938159.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_034947651.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_034952635.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034950916.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034935174.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034943842.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034946814.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034948202.1 5 Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780 "GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome" XP_034937704.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034944235.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_034948480.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034937472.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034947537.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034939878.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034948798.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_034943144.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_034950634.1 9 Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279 "TGF-beta receptor signaling activates SMADs";"UCH proteinases";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer" XP_034933735.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_034949400.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034935809.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_034948447.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_034936767.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034935017.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_034943923.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034941410.1 6 Reactome: R-HSA-2029485;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-1489509;Reactome: R-HSA-114508 "Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis" XP_034936905.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034937134.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034936015.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034947914.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034949590.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_034947052.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_034934518.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_034935180.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_034940621.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide" XP_034940382.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_034940500.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_034948172.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034941418.1 6 Reactome: R-HSA-2024096;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916 "HS-GAG degradation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Hyaluronan uptake and degradation" XP_034942307.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_034940772.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_034937343.1 9 Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430 "Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"Polymerase switching";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation" XP_034948204.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684 "Hedgehog 'off' state";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state" XP_034948561.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034935636.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_034937110.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034935129.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034951830.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034952573.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034940759.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_034951591.1 6 MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle" XP_034933993.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034952331.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_034940188.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034939912.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_034950092.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_034936246.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_034939537.1 17 Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-1834949;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619 "Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cytosolic sensors of pathogen-associated DNA";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN" XP_034935217.1 10 Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_034940853.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_034944581.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_034936361.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_034937656.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034946198.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_034948506.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034940329.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_034943412.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_034947596.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034941444.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034949910.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453 "Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis" XP_034938505.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation" XP_034947801.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_034943462.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_034947843.1 19 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7198;Reactome: R-HSA-380270;MetaCyc: PWY-7220;Reactome: R-HSA-380320;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7226 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_034942308.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034952512.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_034951061.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" XP_034949422.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034935949.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_034939570.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034934838.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_034946980.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034942452.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_034952562.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034945304.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034937169.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034938779.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_034945541.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_034949029.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_034943647.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_034937601.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034945313.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034940325.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_034950681.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation" XP_034935225.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034940345.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_034947308.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034935991.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034951075.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_034941800.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034939106.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034935898.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034948628.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034952448.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_034941027.1 4 MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_034952378.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034944102.1 5 Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" XP_034941283.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-176187 "Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress" XP_034947089.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034947568.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_034948084.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034935563.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_034944599.1 3 Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17 "Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism" XP_034933767.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176412 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C" XP_034940287.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_034945086.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_034950038.1 7 Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400 "Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"RHO GTPases Activate Formins";"PCP/CE pathway" XP_034947314.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000178 "Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions";"ECM proteoglycans" XP_034944583.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_034948664.1 8 Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_034936217.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034936171.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_034948866.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034935072.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034936654.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_034950099.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_034949920.1 4 MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II" XP_034950118.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_034947046.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_034939705.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_034943217.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation" XP_034950562.1 5 KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-71336;Reactome: R-HSA-6798695 "Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Neutrophil degranulation" XP_034943565.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_034933943.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_034939913.1 13 KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537 "Citrate cycle (TCA cycle)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V" XP_034939140.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_034944976.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034942286.1 14 Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation" XP_034936304.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" XP_034934452.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034935321.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034946559.1 6 MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36;MetaCyc: PWY-6174;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)" XP_034945416.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034940189.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034946925.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034937420.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9620244 "Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF activation";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Long-term potentiation" XP_034934328.1 9 MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-5651;MetaCyc: PWY-6309;MetaCyc: PWY-7733;MetaCyc: PWY-7734;Reactome: R-HSA-71240;MetaCyc: PWY-7717;KEGG: 00630+3.5.1.9 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxyquinaldate biosynthesis";"Quinoxaline-2-carboxylate biosynthesis";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Glyoxylate and dicarboxylate metabolism" XP_034937880.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_034949342.1 10 MetaCyc: PWY-7922;Reactome: R-HSA-162699;Reactome: R-HSA-4719377;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7921;Reactome: R-HSA-4717374;MetaCyc: PWY-7661;MetaCyc: PWY-7979;Reactome: R-HSA-4719360;Reactome: R-HSA-913709 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"N-Glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"O-linked glycosylation of mucins" XP_034946394.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_034937391.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034952310.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_034941007.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034947337.1 7 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-418885;Reactome: R-HSA-203641;Reactome: R-HSA-3928662;Reactome: R-HSA-373753 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"DCC mediated attractive signaling";"NOSTRIN mediated eNOS trafficking";"EPHB-mediated forward signaling";"Nephrin family interactions" XP_034937944.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034947617.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034952686.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation" XP_034947348.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_034939514.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_034947780.1 3 Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807 "Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_034950762.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034939682.1 8 KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Oxidative phosphorylation";"Insulin receptor recycling";"Photosynthesis";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_034951158.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_034940559.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_034952395.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034945393.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034938311.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034948625.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034935049.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_034941731.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034934676.1 18 KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053 "Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II" XP_034942643.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034941730.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034948721.1 4 MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1 "Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism" XP_034941050.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_034939956.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_034934564.1 17 KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5789 "Propanoate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_034935307.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034934311.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_034938791.1 7 Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis";"Inositol phosphate metabolism" XP_034942377.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_034951849.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-167243;Reactome: R-HSA-176034;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-6807505 "Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes" XP_034949201.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_034950289.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034940056.1 42 MetaCyc: PWY-6883;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7656;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00623+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-5136;MetaCyc: PWY-5109;MetaCyc: PWY-7007;MetaCyc: PWY-6946;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-6945;MetaCyc: PWY-7726;MetaCyc: PWY-5177;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-6944;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6435;MetaCyc: PWY-7606;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7094 "Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to hexanol (engineered)";"Geraniol degradation";"Limonene and pinene degradation";"Aminobenzoate degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Toluene degradation";"Fatty acid degradation";"2-methylpropene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"Butanoate metabolism";"Pyruvate fermentation to butanol I";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Butanoate metabolism";"Caprolactam degradation";"Lysine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Tryptophan metabolism";"Fatty acid elongation";"Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Fatty acid salvage" XP_034952591.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_034942306.1 12 Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380284 "XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_034942582.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034946192.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_034947057.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_034952726.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_034937008.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_034938784.1 12 KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1 "Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Pyruvate metabolism";"Chitin degradation to ethanol";"Propanoate metabolism";"Methane metabolism";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis" XP_034938441.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_034941388.1 57 Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-532668;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346 "TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis" XP_034947647.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034936357.1 6 Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-194840;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Rho GTPase cycle";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_034951480.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034947998.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_034952651.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034946350.1 4 Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping" XP_034939856.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034946160.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_034934389.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034952636.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034933877.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034952308.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_034944085.1 4 Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_034937335.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892 "Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation" XP_034936011.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_034934273.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_034952724.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_034946193.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7726 "alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_034940790.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034944635.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034944010.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_034945669.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034935308.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034942232.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_034941692.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_034950579.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034948155.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_034946895.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034950879.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "MAP2K and MAPK activation";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation" XP_034934733.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6807505 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes" XP_034945674.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034941381.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_034940992.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_034942606.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_034947928.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_034941520.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_034940702.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034942193.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034946141.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_034945410.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_034937995.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034934470.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034937747.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_034947633.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;MetaCyc: PWY-7511 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination" XP_034934043.1 17 Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034937438.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-877300 "Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"RAF activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling" XP_034941720.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034946851.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_034944819.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_034942543.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034943098.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034946750.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034951368.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034949764.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_034942038.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_034948905.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" XP_034947591.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_034940101.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_034946044.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724 "Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_034943707.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7417 "Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)" XP_034943061.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_034945726.1 13 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-3000157;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Signaling by PDGF";"Laminin interactions";"NCAM1 interactions";"Extracellular matrix organization";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation" XP_034935110.1 32 Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-72165 "mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway" XP_034947132.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_034942830.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_034942871.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_034933631.1 11 Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938 "Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)" XP_034942114.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-611105 "Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport" XP_034951636.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034949012.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-8854518 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"AURKA Activation by TPX2" XP_034948007.1 5 Reactome: R-HSA-5689603;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-2173789;Reactome: R-HSA-917937 "UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"TGF-beta receptor signaling activates SMADs";"Iron uptake and transport" XP_034935617.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_034944856.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034948570.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034949039.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_034935311.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034949198.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_034934212.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034945167.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_034938834.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_034939139.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_034936617.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_034948950.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_034945652.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034950997.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51 "Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism" XP_034935060.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034934848.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505 "Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_034943426.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_034940969.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034940964.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034939712.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex" XP_034950004.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_034947480.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034949023.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_034947519.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_034933942.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_034951029.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034949430.1 20 Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_034944744.1 16 Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-416476;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-9009391 "Regulation of signaling by CBL";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"G alpha (q) signalling events";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"RET signaling";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling" XP_034944703.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_034947593.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_034941981.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_034945249.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_034939159.1 9 MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" XP_034943625.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034950003.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_034941992.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378 "Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling" XP_034935708.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034939830.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_034948446.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_034934663.1 24 Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-68877 "COPI-mediated anterograde transport";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase" XP_034941372.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_034943892.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034945504.1 5 Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426 "Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_034936289.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034943203.1 26 Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606 "LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_034949379.1 8 KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-5744 "Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation" XP_034935304.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034936918.1 4 MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040 "Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis" XP_034945247.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_034941435.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034950899.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034949031.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_034945138.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation" XP_034951744.1 9 Reactome: R-HSA-70263;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1 "Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism" XP_034933581.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034947921.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034941986.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-174411 "Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere" XP_034951603.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034951257.1 57 Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978 "Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_034939797.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_034947291.1 19 Reactome: R-HSA-3928662;Reactome: R-HSA-5627123;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-389359;Reactome: R-HSA-5626467;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-8950505;Reactome: R-HSA-5625970;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-983231 "EPHB-mediated forward signaling";"RHO GTPases activate PAKs";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"CD28 dependent Vav1 pathway";"RHO GTPases activate IQGAPs";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"Rho GTPase cycle";"RHO GTPases Activate Formins";"Myogenesis";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate KTN1";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production" XP_034938830.1 5 MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine" XP_034933678.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034942044.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_034944643.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034948261.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034942506.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" XP_034952264.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_034948192.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_034941701.1 10 Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23 "Hyaluronan uptake and degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Galactose metabolism";"Glycosaminoglycan degradation" XP_034946802.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034949042.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034935050.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034939532.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034943276.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034945026.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_034940922.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034937948.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034941888.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_034937936.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation" XP_034934473.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_034940782.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_034951716.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034947922.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034938454.1 10 MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042 "1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)" XP_034951824.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034949693.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034948293.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-179409 "Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A" XP_034946510.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174084 "APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_034949458.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_034951275.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172 "RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome" XP_034939917.1 1 Reactome: R-HSA-419771 "Opsins" XP_034950311.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034942856.1 7 MetaCyc: PWY-6470;MetaCyc: PWY-5265;MetaCyc: PWY-6471;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;Reactome: R-HSA-446193 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_034947303.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_034934544.1 17 Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-200425;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744 "Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Biotin transport and metabolism";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Fatty acid biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation" XP_034943753.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166 "Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate" XP_034940585.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_034950366.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_034946737.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034939310.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034940919.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034944486.1 29 Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-112382 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex" XP_034940249.1 27 Reactome: R-HSA-975957;Reactome: R-HSA-77588;Reactome: R-HSA-6803529;Reactome: R-HSA-159230;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-159236;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-9010553;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-191859;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975956;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-112382;Reactome: R-HSA-77595 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"FGFR2 alternative splicing";"Transport of the SLBP Dependant Mature mRNA";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"snRNP Assembly";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Formation of RNA Pol II elongation complex";"Processing of Intronless Pre-mRNAs" XP_034939024.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_034946035.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-9609690 "NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"HCMV Early Events" XP_034934287.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034940140.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_034937875.1 8 Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324 "RAF/MAP kinase cascade";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_034942586.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034950112.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_034935760.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034936080.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_034943492.1 7 KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-8004;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Pentose phosphate pathway" XP_034939280.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-186763;Reactome: R-HSA-8875555 "MET receptor recycling";"Regulation of signaling by CBL";"Downstream signal transduction";"MET activates RAP1 and RAC1" XP_034935789.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_034948106.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_034948331.1 17 Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-174084 "APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_034936177.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_034934177.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_034944108.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034943408.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_034950686.1 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_034934275.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034944341.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_034937390.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034941386.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_034937309.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_034949776.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_034940989.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_034948254.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-1257604 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI3K Cascade";"PIP3 activates AKT signaling" XP_034949891.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034947375.1 6 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;Reactome: R-HSA-446210 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine" XP_034943361.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034941653.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_034935975.1 3 MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2 "UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism" XP_034943714.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034935712.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_034937827.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034938595.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034944597.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034946557.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_034943414.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_034939329.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034945359.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_034950731.1 5 MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_034939122.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_034934199.1 6 MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341 "L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_034936049.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034943340.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway" XP_034952371.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034948833.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_034945666.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_034934626.1 14 Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-6453 "Synthesis of PA";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis" XP_034952279.1 4 KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621 "Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism" XP_034936761.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034937236.1 11 Reactome: R-HSA-2173796;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-72163;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-210744 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_034939986.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034951717.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034936970.1 7 KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188 "Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" XP_034937280.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_034946743.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69656 "G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry" XP_034942093.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_034947386.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034934059.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_034936379.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034940466.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034943754.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69091 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Polymerase switching" XP_034946901.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_034948098.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_034936826.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_034936713.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_034942588.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034941135.1 13 MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7226 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_034948430.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_034938999.1 4 Reactome: R-HSA-1614558;MetaCyc: PWY-7927;MetaCyc: PWY-5350;KEGG: 00920+2.8.1.1 "Degradation of cysteine and homocysteine";"Sulfide oxidation IV (mitochondria)";"Thiosulfate disproportionation IV (rhodanese)";"Sulfur metabolism" XP_034938948.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034947741.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_034948688.1 15 Reactome: R-HSA-9665250;Reactome: R-HSA-9665249;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-9665247;Reactome: R-HSA-9665246;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-9634285;Reactome: R-HSA-9665233;Reactome: R-HSA-9665245;Reactome: R-HSA-9665251;Reactome: R-HSA-9665244;Reactome: R-HSA-5637810;Reactome: R-HSA-1227986 "Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to afatinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to neratinib";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2" XP_034946693.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_034950106.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034941328.1 22 Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-389513 "Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling" XP_034943352.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_034934229.1 11 Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167238 "Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation" XP_034943441.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_034934387.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034941889.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_034940914.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_034947720.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_034933927.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_034951803.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_034946176.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_034951569.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034943444.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_034933919.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_034937109.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034937915.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_034949742.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168 "Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034949522.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034947104.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034936574.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_034944242.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034943611.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034945960.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_034935368.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594 "PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events" XP_034942441.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034946670.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034945967.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199 "(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation" XP_034942847.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_034950100.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_034934807.1 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_034939529.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034945083.1 5 Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;Reactome: R-HSA-380994 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_034952639.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation" XP_034935864.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_034949185.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034948555.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_034935467.1 7 Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8 "Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_034947418.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034943439.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034948652.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-167590 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation" XP_034941225.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_034946459.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034938110.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_034936355.1 6 Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism";"3-phosphoinositide degradation" XP_034946900.1 52 Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-1834949;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-9018519;Reactome: R-HSA-73863;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Cytosolic sensors of pathogen-associated DNA";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_034950014.1 6 Reactome: R-HSA-1660517;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;KEGG: 04070+3.1.3.64 "Synthesis of PIPs at the late endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_034934546.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_034933714.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_034935334.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034935765.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_034946393.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_034935395.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_034945778.1 3 Reactome: R-HSA-447043;Reactome: R-HSA-3928664;Reactome: R-HSA-6798695 "Neurofascin interactions";"Ephrin signaling";"Neutrophil degranulation" XP_034938313.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_034942915.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_034935976.1 3 MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2 "UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism" XP_034940934.1 4 Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane" XP_034950990.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_034934434.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_034934432.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_034937697.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" XP_034947574.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034938192.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50 "HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation" XP_034949389.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034936839.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034951360.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034945254.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_034947804.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034950186.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_034943247.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_034941207.1 7 KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1 "Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_034944718.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_034944569.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_034940908.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_034934791.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_034944754.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_034933674.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034948234.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034949030.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034950284.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034946861.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_034945024.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_034949020.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_034942251.1 6 Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation" XP_034936779.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_034942973.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034939685.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_034951050.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034949352.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034944379.1 18 Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783 "Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation" XP_034942154.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_034946349.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_034947745.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_034946876.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_034950074.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034935934.1 2 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_034947134.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_034949850.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_034940062.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034940573.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_034936324.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034948834.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034938891.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_034945184.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_034939869.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034936224.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_034937174.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034942518.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_034944679.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_034934496.1 6 KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes" XP_034948626.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034952329.1 8 KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1 "Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Galactose metabolism" XP_034951944.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034937130.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_034944222.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_034941528.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_034936280.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034949045.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034944580.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_034941725.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_034939317.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034933843.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_034950090.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_034952386.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034946156.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_034937909.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_034943013.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_034946398.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_034939332.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034951561.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_034942890.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034949463.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034946194.1 20 MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7858 "Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II" XP_034947750.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_034944655.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_034944594.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034950424.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_034944286.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034943146.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_034952538.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034942282.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_034944554.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034948147.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034940401.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_034940067.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034939452.1 56 Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858 "CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity" XP_034951239.1 7 MetaCyc: PWY-6737;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-6724;Reactome: R-HSA-70221 "Starch degradation V";"Glycogen degradation II";"Starch and sucrose metabolism";"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch degradation II";"Glycogen breakdown (glycogenolysis)" XP_034942621.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids" XP_034944307.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034943420.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_034949655.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_034951504.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_034940163.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_034942841.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034943467.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes" XP_034951032.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034945964.1 14 MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)" XP_034937402.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034933724.1 4 MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922 "(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis" XP_034941235.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_034952352.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_034945124.1 7 Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-390471;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC" XP_034941306.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034937554.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-936837 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"RAF activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases" XP_034940678.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_034944579.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_034947693.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034934430.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_034945300.1 6 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427359 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression" XP_034952385.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034933815.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_034943650.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034947215.1 15 Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884 "Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX" XP_034946833.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034945982.1 2 KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841 "Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_034952315.1 7 KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_034940509.1 5 MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821 "Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_034939409.1 42 Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-427359;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-977225;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-9616222;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-3214815;Reactome: R-HSA-1912408;Reactome: R-HSA-2299718;Reactome: R-HSA-606279;Reactome: R-HSA-8939236;Reactome: R-HSA-69473;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-3214858;Reactome: R-HSA-212300 "Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"Meiotic synapsis";"SIRT1 negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"Amyloid fiber formation";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA methylation";"HCMV Late Events";"HDACs deacetylate histones";"Pre-NOTCH Transcription and Translation";"Condensation of Prophase Chromosomes";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M DNA damage checkpoint";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA" XP_034946643.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034948444.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_034937156.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-112043 "Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events" XP_034937385.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034946981.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_034946874.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034950153.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_034949319.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379 "ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres" XP_034942103.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_034949326.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034946934.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034936420.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034946083.1 31 MetaCyc: PWY-5142;Reactome: R-HSA-75105;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;MetaCyc: PWY-5366;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWY-7746;MetaCyc: PWY-8012;MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-6113;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-8049;MetaCyc: PWY-5973;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;MetaCyc: PWY-7858;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5367;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-8047;MetaCyc: PWY-5989 "Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Pederin biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Petroselinate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Bryostatin biosynthesis";"Stearate biosynthesis II (bacteria and plants)" XP_034948464.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034938925.1 9 KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_034941993.1 11 Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378 "Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling" XP_034948718.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_034941221.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_034948632.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034945309.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034944516.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_034934866.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034945727.1 13 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-186797;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Signaling by PDGF";"ECM proteoglycans";"Laminin interactions";"NCAM1 interactions";"Integrin cell surface interactions";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures" XP_034945633.1 6 Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_034934403.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_034941280.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_034945732.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_034945243.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_034948466.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949726.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_034934394.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034940444.1 4 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_034948653.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_034942591.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_034947360.1 17 Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-6804756;Reactome: R-HSA-69601;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04151+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-8953750;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Thermogenesis";"Signaling by SCF-KIT";"Regulation of TP53 Activity through Phosphorylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"PI3K-Akt signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Transcriptional Regulation by E2F6";"Human papillomavirus infection";"mTOR signaling pathway" XP_034937369.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_034941554.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034949214.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034946927.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation" XP_034941729.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034951790.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034940493.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957 "Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034944562.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_034937112.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034939515.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_034943438.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_034936548.1 5 MetaCyc: PWY-7782;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_034938508.1 57 Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-68949 "Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin" XP_034934465.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034950519.1 5 MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7204 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)" XP_034949407.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034949841.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034945183.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_034952072.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_034945312.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_034935713.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_034948590.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034934490.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_034950201.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_034941734.1 5 Reactome: R-HSA-376172;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-171007 "DSCAM interactions";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events" XP_034952509.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_034948847.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034945517.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_034937353.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF activation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" XP_034942982.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034934593.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034935556.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034937108.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034942571.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_034947302.1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_034943051.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034944541.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034939414.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_034944967.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204 "Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_034939694.1 7 KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;Reactome: R-HSA-174403;MetaCyc: PWY-7255 "Glutathione metabolism";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)" XP_034942749.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_034942676.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_034941513.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034936401.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_034943153.1 9 MetaCyc: PWY-7411;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_034945208.1 5 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation" XP_034936076.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_034935982.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_034943140.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_034937516.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034945891.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-159227 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA" XP_034943213.1 26 Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-5621575 "TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"CD209 (DC-SIGN) signaling" XP_034935404.1 3 KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism" XP_034949015.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_034949035.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034951568.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034945206.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034935777.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_034950473.1 14 Reactome: R-HSA-4086398;MetaCyc: PWY-8052;Reactome: R-HSA-399997;Reactome: R-HSA-434316;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-500657;Reactome: R-HSA-418217 "Ca2+ pathway";"2-arachidonoylglycerol biosynthesis";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Inositol phosphate metabolism";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta" XP_034939454.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_034936022.1 6 KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-5663 "Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I" XP_034946902.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_034952416.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_034937086.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034942042.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_034936634.1 182 Reactome: R-HSA-69017;Reactome: R-HSA-6782210;Reactome: R-HSA-75815;Reactome: R-HSA-2122947;Reactome: R-HSA-5205685;Reactome: R-HSA-8852276;Reactome: R-HSA-5655862;Reactome: R-HSA-4641257;Reactome: R-HSA-8948747;Reactome: R-HSA-2979096;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-5654726;Reactome: R-HSA-1236382;Reactome: R-HSA-201681;Reactome: R-HSA-5357956;Reactome: R-HSA-5696397;Reactome: R-HSA-5362768;Reactome: R-HSA-8866652;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-2173796;Reactome: R-HSA-9033241;Reactome: R-HSA-168638;Reactome: R-HSA-1799339;Reactome: R-HSA-8939902;Reactome: R-HSA-450302;Reactome: R-HSA-382556;Reactome: R-HSA-975956;Reactome: R-HSA-5696395;Reactome: R-HSA-975163;Reactome: R-HSA-9633012;Reactome: R-HSA-9604323;Reactome: R-HSA-3322077;Reactome: R-HSA-209560;Reactome: R-HSA-2691232;Reactome: R-HSA-1169408;Reactome: R-HSA-180534;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-5607761;Reactome: R-HSA-110314;Reactome: R-HSA-9613829;Reactome: R-HSA-936964;Reactome: R-HSA-8856828;Reactome: R-HSA-4641263;Reactome: R-HSA-8863795;Reactome: R-HSA-174154;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-2894862;Reactome: R-HSA-9646399;Reactome: R-HSA-9645460;Reactome: R-HSA-174178;Reactome: R-HSA-9013973;Reactome: R-HSA-1295596;Reactome: R-HSA-445989;Reactome: R-HSA-174113;Reactome: R-HSA-6804760;Reactome: R-HSA-977225;Reactome: R-HSA-912631;Reactome: R-HSA-8866654;Reactome: R-HSA-5668541;Reactome: R-HSA-69231;Reactome: R-HSA-5676590;Reactome: R-HSA-936440;Reactome: R-HSA-72702;Reactome: R-HSA-8875360;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-9013507;Reactome: R-HSA-2672351;Reactome: R-HSA-8876493;Reactome: R-HSA-6807004;Reactome: R-HSA-5656121;Reactome: R-HSA-6783310;Reactome: R-HSA-5357905;Reactome: R-HSA-72706;Reactome: R-HSA-5675221;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-5685942;Reactome: R-HSA-3769402;Reactome: R-HSA-5654732;Reactome: R-HSA-2173791;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-5654727;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-6781823;Reactome: R-HSA-72764;Reactome: R-HSA-9636383;Reactome: R-HSA-1358803;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-192823;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-3134975;Reactome: R-HSA-1253288;Reactome: R-HSA-532668;Reactome: R-HSA-5693607;Reactome: R-HSA-937042;Reactome: R-HSA-174490;Reactome: R-HSA-182971;Reactome: R-HSA-5689603;Reactome: R-HSA-209543;Reactome: R-HSA-5689901;Reactome: R-HSA-205043;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-975144;Reactome: R-HSA-901032;Reactome: R-HSA-2644606;Reactome: R-HSA-6782135;Reactome: R-HSA-174048;Reactome: R-HSA-175474;Reactome: R-HSA-2408557;Reactome: R-HSA-5689877;Reactome: R-HSA-156902;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-3785653;Reactome: R-HSA-8856825;Reactome: R-HSA-5675482;Reactome: R-HSA-2173788;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-6781827;Reactome: R-HSA-6804756;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-156827;Reactome: R-HSA-180585;Reactome: R-HSA-8849469;Reactome: R-HSA-2565942;Reactome: R-HSA-400253;Reactome: R-HSA-4608870;Reactome: R-HSA-937039;Reactome: R-HSA-937072;Reactome: R-HSA-917729;Reactome: R-HSA-168928;Reactome: R-HSA-110312;Reactome: R-HSA-9014325;Reactome: R-HSA-168927;Reactome: R-HSA-72695;Reactome: R-HSA-5693565;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-2559580;Reactome: R-HSA-9615710;Reactome: R-HSA-917937;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-2122948;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-2559585;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-162588;Reactome: R-HSA-202424;Reactome: R-HSA-2173795;Reactome: R-HSA-8948751;Reactome: R-HSA-179409;Reactome: R-HSA-69541;Reactome: R-HSA-72649;Reactome: R-HSA-5654733;Reactome: R-HSA-6804757;Reactome: R-HSA-9637628;Reactome: R-HSA-8941858;Reactome: R-HSA-2559582;Reactome: R-HSA-1169091;Reactome: R-HSA-450321;Reactome: R-HSA-5684264;Reactome: R-HSA-975957;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-937041;Reactome: R-HSA-975110 "CDK-mediated phosphorylation and removal of Cdc6";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ubiquitin-dependent degradation of Cyclin D";"NOTCH1 Intracellular Domain Regulates Transcription";"Pink/Parkin Mediated Mitophagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translesion synthesis by POLK";"Degradation of AXIN";"Regulation of PTEN localization";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of FGFR1 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"TCF dependent signaling in response to WNT";"TNFR1-induced NFkappaB signaling pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Peroxisomal protein import";"NOD1/2 Signaling Pathway";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of RUNX2 expression and activity";"activated TAK1 mediates p38 MAPK activation";"ABC-family proteins mediated transport";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of Incision Complex in GG-NER";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Negative regulation of NOTCH4 signaling";"Glycogen synthesis";"NF-kB is activated and signals survival";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"ISG15 antiviral mechanism";"Vpu mediated degradation of CD4";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Dectin-1 mediated noncanonical NF-kB signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Chaperone Mediated Autophagy";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Downregulation of ERBB2 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Aggrephagy";"Alpha-protein kinase 1 signaling pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TICAM1-dependent activation of IRF3/IRF7";"Spry regulation of FGF signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of TP53 Activity through Methylation";"Amyloid fiber formation";"Regulation of signaling by CBL";"E3 ubiquitin ligases ubiquitinate target proteins";"TNFR2 non-canonical NF-kB pathway";"Cyclin D associated events in G1";"NIK-->noncanonical NF-kB signaling";"Negative regulators of DDX58/IFIH1 signaling";"Ribosomal scanning and start codon recognition";"InlB-mediated entry of Listeria monocytogenes into host cell";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Stimuli-sensing channels";"InlA-mediated entry of Listeria monocytogenes into host cells";"Negative regulation of MET activity";"Translesion synthesis by POLI";"Fanconi Anemia Pathway";"Regulation of TNFR1 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Negative regulation of MAPK pathway";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"HDR through Homologous Recombination (HRR)";"Deactivation of the beta-catenin transactivating complex";"Negative regulation of FGFR3 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Negative regulation of FGFR2 signaling";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Formation of TC-NER Pre-Incision Complex";"Eukaryotic Translation Termination";"Prevention of phagosomal-lysosomal fusion";"Downregulation of ERBB2:ERBB3 signaling";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"Viral mRNA Translation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Regulation of innate immune responses to cytosolic DNA";"Downregulation of ERBB4 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Processing of DNA double-strand break ends";"IRAK2 mediated activation of TAK1 complex";"Membrane binding and targetting of GAG proteins";"EGFR downregulation";"UCH proteinases";"p75NTR recruits signalling complexes";"Metalloprotease DUBs";"NRIF signals cell death from the nucleus";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"ER Quality Control Compartment (ERQC)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Dual incision in TC-NER";"APC/C:Cdc20 mediated degradation of Cyclin B";"Assembly Of The HIV Virion";"Selenocysteine synthesis";"Josephin domain DUBs";"Peptide chain elongation";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Myoclonic epilepsy of Lafora";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of necroptotic cell death";"Downregulation of TGF-beta receptor signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Activity through Phosphorylation";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Vif-mediated degradation of APOBEC3G";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of PLK1 Activity at G2/M Transition";"Circadian Clock";"Asymmetric localization of PCP proteins";"IRAK1 recruits IKK complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Endosomal Sorting Complex Required For Transport (ESCRT)";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Translesion synthesis by REV1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TICAM1, RIP1-mediated IKK complex recruitment";"Formation of the ternary complex, and subsequently, the 43S complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage Recognition in GG-NER";"Neddylation";"Oxidative Stress Induced Senescence";"Late endosomal microautophagy";"Iron uptake and transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activated NOTCH1 Transmits Signal to the Nucleus";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oncogene Induced Senescence";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Budding and maturation of HIV virion";"Downstream TCR signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of PTEN stability and activity";"APC-Cdc20 mediated degradation of Nek2A";"Stabilization of p53";"Translation initiation complex formation";"Negative regulation of FGFR4 signaling";"Regulation of TP53 Degradation";"Modulation by Mtb of host immune system";"Regulation of RUNX3 expression and activity";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of NF-kappaB in B cells";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"IKK complex recruitment mediated by RIP1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling" XP_034950026.1 4 KEGG: 00230+4.1.1.97;MetaCyc: PWY-7394;MetaCyc: PWY-7849;MetaCyc: PWY-5691 "Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Urate conversion to allantoin I" XP_034943227.1 18 KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1;KEGG: 00220+2.6.1.1 "Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Novobiocin biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis" XP_034934955.1 6 Reactome: R-HSA-71240;MetaCyc: PWY-7717;MetaCyc: PWY-6309;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-5651 "Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_034948924.1 5 KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22 "Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_034951099.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034951601.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034946236.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_034934871.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034939542.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_034936212.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_034938340.1 8 KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1 "Galactose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism" XP_034945997.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034942741.1 5 Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)" XP_034941112.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination" XP_034937836.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034943910.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034936039.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_034945600.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034950062.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_034938098.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_034939506.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034950282.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034951074.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_034942565.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034934780.1 16 Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-164939;Reactome: R-HSA-167590 "Recycling pathway of L1";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD4 Down-regulation" XP_034937419.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77588 "snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_034946529.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_034935850.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_034951772.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_034948421.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_034950200.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_034943868.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_034945716.1 3 Reactome: R-HSA-6799198;Reactome: R-HSA-1268020;Reactome: R-HSA-611105 "Complex I biogenesis";"Mitochondrial protein import";"Respiratory electron transport" XP_034936146.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949097.1 4 MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49 "Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism" XP_034935059.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034941474.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_034951639.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034939736.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034951035.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034938021.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" XP_034941223.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_034937386.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034936991.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034937256.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034952449.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_034946951.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034950979.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034947533.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_034935082.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_034948431.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_034947794.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034939269.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034937304.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034939592.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034949838.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034945250.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_034939326.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034937175.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034939328.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034945456.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034943945.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_034950466.1 12 Reactome: R-HSA-2660826;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-75893;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-982772 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"TNF signaling";"Collagen degradation";"Signaling by EGFR";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Growth hormone receptor signaling" XP_034942006.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_034940899.1 7 Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-165054 "tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA" XP_034952574.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034942612.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy" XP_034946429.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034941912.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_034937176.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034944940.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034939016.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7417 "Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)" XP_034950600.1 18 MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4 "Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism" XP_034936305.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" XP_034937968.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034939995.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_034944867.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034934097.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034934696.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034935944.1 14 Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_034939015.1 14 MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8051 "CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I" XP_034948137.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034937655.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034948648.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034937988.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034946840.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034951200.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_034933774.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER" XP_034948988.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_034933579.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034934367.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_034937129.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_034940011.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_034933686.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_034941334.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034938867.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_034939171.1 8 MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-7524 "Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)" XP_034947256.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034944109.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-2142789 "Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquinol biosynthesis" XP_034944666.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_034942455.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_034943148.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034944239.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034935064.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034945963.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724 "Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_034952285.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_034947840.1 19 MetaCyc: PWY-7224;Reactome: R-HSA-380320;MetaCyc: PWY-7220;MetaCyc: PWY-7198;Reactome: R-HSA-380270;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-6545 "Purine deoxyribonucleosides salvage";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_034943210.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion" XP_034939944.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034942711.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_034938114.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_034936238.1 10 KEGG: 05163+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-9027276;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153 "Human cytomegalovirus infection";"Inositol phosphate metabolism";"mTOR signaling pathway";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Human papillomavirus infection" XP_034941633.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_034945422.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034943569.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" XP_034942967.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952 "Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions" XP_034949194.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034943035.1 4 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_034944407.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_034940402.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_034942023.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034946926.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034936807.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034944743.1 16 Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-1660499 "Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"Interleukin receptor SHC signaling";"RET signaling";"Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"Interleukin-7 signaling";"G alpha (q) signalling events";"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane" XP_034946738.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034942280.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_034949908.1 10 MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7587 "Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)" XP_034950439.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_034946099.1 10 Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017 "Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_034935201.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700 "TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_034943925.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034937635.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_034951293.1 24 Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-392451 "G-protein activation";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma" XP_034951140.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_034939272.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034935374.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_034950565.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034939428.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034951892.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034941604.1 8 KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;MetaCyc: PWY-5739;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-66 "Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)" XP_034934136.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_034938786.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" XP_034940952.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034942278.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034950693.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_034936210.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_034940398.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034950949.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034946920.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" XP_034951781.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616 "Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication" XP_034934616.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_034937368.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_034938501.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_034946798.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034949777.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_034935317.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034948115.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_034951219.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_034935289.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034942433.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_034946223.1 7 MetaCyc: PWY-6610;MetaCyc: PWY-7805;Reactome: R-HSA-6798695;MetaCyc: PWY-7807;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6605 "Adenine salvage";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation";"Glyphosate degradation III";"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage II" XP_034939982.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034946363.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034939330.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034951406.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_034941910.1 25 Reactome: R-HSA-8939242;Reactome: R-HSA-8939247;Reactome: R-HSA-8941858;Reactome: R-HSA-8941284;Reactome: R-HSA-8941332;Reactome: R-HSA-8939256;Reactome: R-HSA-9616222;Reactome: R-HSA-8935964;Reactome: R-HSA-8939243;Reactome: R-HSA-8939245;Reactome: R-HSA-8951911;Reactome: R-HSA-8936459;Reactome: R-HSA-8951936;Reactome: R-HSA-8934593;Reactome: R-HSA-8940973;Reactome: R-HSA-8931987;Reactome: R-HSA-8939246;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-8877330;Reactome: R-HSA-8941326;Reactome: R-HSA-8949275;Reactome: R-HSA-9018519;Reactome: R-HSA-8941333;Reactome: R-HSA-8878166 "RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Regulation of RUNX3 expression and activity";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates expression of components of tight junctions";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 regulates p14-ARF";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates bone development";"RUNX3 Regulates Immune Response and Cell Migration";"Estrogen-dependent gene expression";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Transcriptional regulation by RUNX2" XP_034946907.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034945999.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034945027.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_034939421.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041 "Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_034949343.1 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" XP_034940355.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034947270.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034936202.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034948032.1 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" XP_034946908.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_034947489.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation" XP_034938129.1 9 KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" XP_034942273.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_034938936.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_034939131.1 16 Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692 "Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity" XP_034936585.1 11 Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986 "Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"Signaling by ERBB2" XP_034939346.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69091 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Polymerase switching" XP_034936216.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034937061.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034947756.1 52 Reactome: R-HSA-6782210;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-76061;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_034935199.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8943723 "Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation" XP_034949884.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_034948631.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034939951.1 3 Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361 "Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins" XP_034939446.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_034948945.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_034951100.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_034949060.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_034938373.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_034944025.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_034940718.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034943717.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034943323.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_034944596.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034950635.1 9 Reactome: R-HSA-2173788;Reactome: R-HSA-3642279;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532 "Downregulation of TGF-beta receptor signaling";"TGFBR2 MSI Frameshift Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"TGFBR1 KD Mutants in Cancer" XP_034938814.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_034951957.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" XP_034945634.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-416993 "G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors" XP_034933635.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_034947444.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841 "Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines" XP_034947797.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_034948323.1 5 KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7185;MetaCyc: PWY-7177 "Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II" XP_034942512.1 6 MetaCyc: PWY-6118;MetaCyc: PWY-6952;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA" XP_034944500.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_034946530.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_034943138.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus" XP_034942802.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034946508.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034937107.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034934371.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034951253.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_034952490.1 8 KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086 "Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_034936060.1 5 MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_034939983.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034943520.1 6 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_034941690.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_034937105.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034939582.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034936801.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_034936184.1 10 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661;MetaCyc: PWY-6361;MetaCyc: PWY-6372 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" XP_034946113.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)" XP_034948991.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034946109.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_034941110.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034949199.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034938402.1 16 Reactome: R-HSA-1251985;Reactome: R-HSA-6811558;Reactome: R-HSA-1236394;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-1250342;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993 "Nuclear signaling by ERBB4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB4";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"PI3K events in ERBB4 signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling" XP_034946803.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034938150.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_034942581.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" XP_034951610.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034940303.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110373 "POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_034942972.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034939344.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_034946402.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553 "ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs" XP_034943832.1 5 Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579 "Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ" XP_034949419.1 12 Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-193692 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR" XP_034940161.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_034943966.1 4 Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_034939363.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034949709.1 7 Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_034944115.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_034940346.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_034943230.1 26 Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-918233 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway" XP_034943915.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174084 "APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_034947205.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" XP_034951040.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034943857.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034937947.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034941053.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_034942563.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_034939691.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_034945936.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_034948153.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034937291.1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_034941311.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034938790.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_034950238.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034941933.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034945974.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_034948076.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034942595.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_034939735.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" XP_034943442.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_034934565.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_034951743.1 9 Reactome: R-HSA-70263;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1 "Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism" XP_034942860.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_034936327.1 7 KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484 "Methane metabolism";"Gluconeogenesis";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_034943560.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034942579.1 52 Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-1236974 "G2/M Checkpoints";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway" XP_034937398.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034942216.1 18 KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166 "Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Synthesis of PA" XP_034941691.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_034951592.1 6 MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5744 "Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation" XP_034936831.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034940975.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034946245.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_034951191.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_034943350.1 57 Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664 "Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation" XP_034938201.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_034936949.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034940132.1 30 Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-2564830;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-72086 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Cytosolic iron-sulfur cluster assembly";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"mRNA Capping" XP_034948216.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_034945970.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_034939801.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_034935466.1 7 MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205 "L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose" XP_034939201.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_034951343.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034934620.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_034943159.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034942400.1 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661 "Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation" XP_034941001.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034943523.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_034952084.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_034943074.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_034946923.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034948285.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174084 "APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_034937308.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034934286.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034951979.1 8 Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1 "Surfactant metabolism";"Neutrophil degranulation";"Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II" XP_034937963.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034945439.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034939134.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes" XP_034937413.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034945444.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_034946271.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_034942734.1 14 Reactome: R-HSA-168333;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-69273;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128 "NEP/NS2 Interacts with the Cellular Export Machinery";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling" XP_034949851.1 19 Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"VLDL assembly";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"VLDL clearance";"LDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Chylomicron clearance";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis" XP_034949382.1 8 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7115 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_034949976.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_034949646.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-179409 "Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A" XP_034940822.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277 "Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex" XP_034948828.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034941717.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_034950359.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_034944219.1 30 Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-400253;Reactome: R-HSA-1170546;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-2894862;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-2644607;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-2565942;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761 "Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Circadian Clock";"Prolactin receptor signaling";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Neddylation";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling" XP_034943881.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034934057.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034946959.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749 "Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs" XP_034951006.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_034949026.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034936717.1 9 MetaCyc: PWY-6147;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Preq0 biosynthesis";"Folate biosynthesis" XP_034936551.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_034935872.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_034940762.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_034944099.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034951198.1 14 Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-674695 "Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events" XP_034945889.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034946009.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_034940945.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_034933607.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_034938164.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_034935025.1 7 Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-606279 "HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"UCH proteinases";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_034952633.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034951604.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034939477.1 4 Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping" XP_034949521.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034946638.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_034942454.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170 "Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_034949024.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_034939319.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034949027.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_034940907.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_034950387.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_034935055.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034944572.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_034943071.1 4 Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2 "Selenocysteine synthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_034936385.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68689 "Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex" XP_034940340.1 3 MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581 "Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_034936869.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_034952412.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658 "COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_034940849.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034946952.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_034952404.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-198693 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus" XP_034934309.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_034939619.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_034948846.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034935319.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_034948641.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation" XP_034946719.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_034944249.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport" XP_034951885.1 9 MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Inositol phosphate metabolism";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" XP_034952314.1 12 MetaCyc: PWY-5856;Reactome: R-HSA-1268020;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-6978;MetaCyc: PWY-5857;MetaCyc: PWY-5855;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-6708 "Ubiquinol-9 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_034944184.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034951187.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_034934545.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_034937740.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034941282.1 4 Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880 "Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Ub-specific processing proteases" XP_034943103.1 10 KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10 "Butanoate metabolism";"PPARA activates gene expression";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Valine, leucine and isoleucine degradation";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies" XP_034949629.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_034951210.1 15 Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939 "G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)" XP_034935656.1 57 Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664 "Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation" XP_034943590.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034934449.1 7 Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-983168;Reactome: R-HSA-5693565 "Processing of DNA double-strand break ends";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Antigen processing: Ubiquitination & Proteasome degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034934670.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034947286.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034936624.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_034948250.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_034939149.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_034952278.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034949631.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_034936563.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034946827.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034948843.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034942769.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034936211.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_034948440.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_034944864.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity" XP_034938745.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_034934402.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034937835.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-211976 "PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Phase I - Functionalization of compounds";"Endogenous sterols" XP_034949048.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_034937341.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034935290.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034947118.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_034952444.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_034948171.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034946911.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_034952466.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_034943070.1 6 KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17 "Caprolactam degradation";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway" XP_034943580.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034948622.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034943983.1 22 MetaCyc: PWY-7049;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-6433;MetaCyc: PWY-7053;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-8041;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6958;MetaCyc: PWY-7728;MetaCyc: PWY-7601;MetaCyc: PWY-6598 "Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis" XP_034948291.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034940926.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_034939459.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_034946145.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034944537.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034946848.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_034949759.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034939132.1 16 Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408 "MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation" XP_034946406.1 7 Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans" XP_034945120.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034937128.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_034943962.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_034952026.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_034934736.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167161 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation" XP_034947197.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034952572.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034951135.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_034949724.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_034948287.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034943419.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034946889.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034950246.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_034935051.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034950300.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034934431.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_034943804.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034940643.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_034935810.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_034952700.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_034940755.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_034935948.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034949725.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_034947370.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034939471.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA" XP_034942592.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034937643.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_034950467.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_034937087.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034951366.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034951238.1 7 MetaCyc: PWY-5941;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6724 "Glycogen degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Neutrophil degranulation";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation II" XP_034940933.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_034949095.1 4 KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004 "Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I" XP_034934266.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_034947381.1 4 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)" XP_034940957.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034952086.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_034944702.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" XP_034936384.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex" XP_034938116.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_034950281.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034952197.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_034940162.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_034947597.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034945743.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034944060.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_034950790.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172 "RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome" XP_034936964.1 6 MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_034935302.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034947262.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034941051.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_034942748.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_034943488.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_034937330.1 20 MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6 "10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism" XP_034936218.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034946651.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_034949412.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_034940468.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034938415.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" XP_034950998.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7417 "CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)" XP_034938504.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034936147.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034937067.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_034936945.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-606279 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_034951787.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034938085.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_034938628.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_034943461.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034947280.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034952456.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_034935378.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034937739.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034948425.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_034934734.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162 "RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape" XP_034940915.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_034935508.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_034949320.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000178 "Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions";"ECM proteoglycans" XP_034941459.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_034941928.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034947572.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_034947909.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034937825.1 4 Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-196741 "Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_034942287.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034938347.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034936871.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034943151.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_034934475.1 24 Reactome: R-HSA-5610783;Reactome: R-HSA-8963896;Reactome: R-HSA-432040;Reactome: R-HSA-5687128;Reactome: R-HSA-164378;Reactome: R-HSA-111931;Reactome: R-HSA-392517;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-5621575;Reactome: R-HSA-5610787;Reactome: R-HSA-9634600;Reactome: R-HSA-163358;KEGG: 04150+2.7.11.11;Reactome: R-HSA-422356;Reactome: R-HSA-5610785;Reactome: R-HSA-8853659;Reactome: R-HSA-4420097;Reactome: R-HSA-5610780;Reactome: R-HSA-381676;Reactome: R-HSA-9010642;Reactome: R-HSA-163560;Reactome: R-HSA-163615 "Degradation of GLI2 by the proteasome";"HDL assembly";"Vasopressin regulates renal water homeostasis via Aquaporins";"MAPK6/MAPK4 signaling";"PKA activation in glucagon signalling";"PKA-mediated phosphorylation of CREB";"Rap1 signalling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"CD209 (DC-SIGN) signaling";"Hedgehog 'off' state";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"PKA-mediated phosphorylation of key metabolic factors";"mTOR signaling pathway";"Regulation of insulin secretion";"GLI3 is processed to GLI3R by the proteasome";"RET signaling";"VEGFA-VEGFR2 Pathway";"Degradation of GLI1 by the proteasome";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ROBO receptors bind AKAP5";"Triglyceride catabolism";"PKA activation" XP_034937931.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_034941288.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_034942614.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_034942624.1 15 MetaCyc: PWY-7218;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Purine metabolism" XP_034944678.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_034951491.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034949802.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_034951993.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034937458.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034944598.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034950573.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034948304.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912420 "Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi" XP_034946974.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034952580.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_034933866.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis" XP_034938626.1 1 Reactome: R-HSA-419771 "Opsins" XP_034943572.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034933867.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034942545.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_034952031.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034942819.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_034934519.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_034942667.1 34 Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-69231;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin D associated events in G1";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"RNA polymerase II transcribes snRNA genes" XP_034944273.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034943904.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_034945044.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_034934669.1 18 Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925 "Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG" XP_034937563.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034944447.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_034934979.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034947521.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_034948777.1 12 KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417 "Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)" XP_034942266.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034943703.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_034946728.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_034940124.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_034940026.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034947749.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_034949740.1 16 Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-8951664;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-112382 "Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Neddylation";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex" XP_034942836.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_034934276.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_034948536.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034951499.1 5 MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_034943221.1 26 Reactome: R-HSA-3134973;Reactome: R-HSA-9617629;Reactome: R-HSA-1234158;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947 "LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription" XP_034948556.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034942125.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_034946611.1 12 KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053 "Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II" XP_034951711.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69656 "G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry" XP_034942349.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_034941385.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034944069.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034950174.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_034942798.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_034942928.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034945097.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034951206.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034934625.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367 "Neutrophil degranulation";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines" XP_034952406.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034952065.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_034952547.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_034940400.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_034937401.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034944309.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034951037.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034943942.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_034947717.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_034941920.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_034948656.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034940498.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_034943257.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_034942999.1 10 Reactome: R-HSA-72702;Reactome: R-HSA-72731;Reactome: R-HSA-72706;Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Recycling of eIF2:GDP";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PERK regulates gene expression";"ABC-family proteins mediated transport";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034945774.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034947600.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034949317.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083 "ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions" XP_034941850.1 6 Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957 "BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_034945644.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034937356.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034947516.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_034946912.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_034952507.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_034935871.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034940341.1 3 MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9 "Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_034949986.1 5 KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_034935752.1 5 KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00680+1.1.1.95 "Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism" XP_034935078.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034942013.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_034935943.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-4086398 "Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway" XP_034952411.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_034940923.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034949212.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034938325.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_034949566.1 12 Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-450408 "mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_034948471.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034950052.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_034938485.1 13 MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;Reactome: R-HSA-74259 "Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Purine catabolism" XP_034941308.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034935390.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_034938993.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_034945736.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_034941587.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_034948629.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034938719.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-111367 "mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs" XP_034944955.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_034950275.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034947357.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034952240.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034949519.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034945635.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_034952641.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172 "RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome" XP_034948017.1 6 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-264876;Reactome: R-HSA-6811438 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Insulin processing";"Intra-Golgi traffic" XP_034941305.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034952373.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034937445.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802946 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants" XP_034949718.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034935223.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034951713.1 10 MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-5497;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-2201 "Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I" XP_034936091.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034936666.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034949757.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_034951216.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_034942134.1 4 KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943 "Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates" XP_034949952.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034952440.1 4 Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034943269.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034937053.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034946138.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_034950641.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034936755.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_034942378.1 2 Reactome: R-HSA-430039;MetaCyc: PWY-6938 "mRNA decay by 5' to 3' exoribonuclease";"NADH repair" XP_034936531.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034943706.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;Reactome: R-HSA-1483166 "Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA" XP_034947788.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034942626.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034934451.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_034941143.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034951659.1 13 KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1 "Thermogenesis";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection" XP_034944953.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569 "ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_034933663.1 4 Reactome: R-HSA-156581;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315 "Methylation";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol" XP_034941735.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1" XP_034946361.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034940592.1 3 KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_034951211.1 15 Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938 "Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)" XP_034940016.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_034938901.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_034949941.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034952510.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_034950948.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034937650.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034937168.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034942868.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041 "MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1" XP_034942039.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_034945985.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_034949579.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_034937412.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892 "Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation" XP_034939629.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034937083.1 8 MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_034942704.1 3 Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271 "GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_034946067.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_034933670.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034949312.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159 "Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling" XP_034937041.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034950950.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_034937122.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034946713.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034946362.1 11 Reactome: R-HSA-389948;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-877312;Reactome: R-HSA-909733;Reactome: R-HSA-432142;Reactome: R-HSA-512988;Reactome: R-HSA-912694;Reactome: R-HSA-391160 "PD-1 signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"PECAM1 interactions";"Interleukin-37 signaling";"Regulation of IFNG signaling";"Interferon alpha/beta signaling";"Platelet sensitization by LDL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling";"Signal regulatory protein family interactions" XP_034941404.1 52 Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-6796648;Reactome: R-HSA-76061;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-73980;Reactome: R-HSA-167161;Reactome: R-HSA-749476;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-73863;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-73780 "Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Termination";"HIV Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Termination";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation" XP_034951440.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034946652.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_034942402.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034940824.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202 "Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition" XP_034942117.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034942691.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034948861.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034942594.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034939005.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_034936837.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034938199.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_034943053.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_034942771.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034952487.1 8 Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00010+1.1.1.27 "Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycolysis / Gluconeogenesis" XP_034939937.1 9 Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3560801 "Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD" XP_034948027.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_034945668.1 9 KEGG: 00950+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00130+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00401+2.6.1.5 "Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Tyrosine catabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis" XP_034951811.1 4 Reactome: R-HSA-6787450;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol" XP_034934390.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034939615.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034935573.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_034942022.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472 "Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_034937617.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_034951130.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes" XP_034939499.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_034935552.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_034944229.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034941136.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_034951137.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364 "Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_034936356.1 6 MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36 "3-phosphoinositide degradation";"Inositol phosphate metabolism";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system" XP_034943365.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_034943941.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_034943968.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_034952640.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" XP_034941517.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034947350.1 3 Reactome: R-HSA-195399;Reactome: R-HSA-114608;Reactome: R-HSA-194313 "VEGF binds to VEGFR leading to receptor dimerization";"Platelet degranulation";"VEGF ligand-receptor interactions" XP_034943169.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034944240.1 12 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-210744 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_034949541.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034941976.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_034937987.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034947207.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034947288.1 57 Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276 "Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of AXIN";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_034946801.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034940569.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_034937394.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034944488.1 29 Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"HIV Transcription Initiation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_034943246.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_034947953.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034948876.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034939952.1 16 MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;Reactome: R-HSA-2046106;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-2046105 "(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"alpha-linolenic acid (ALA) metabolism";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Linoleic acid (LA) metabolism" XP_034948255.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_034950049.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034938835.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034949633.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034941487.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_034937789.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034947169.1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" XP_034945365.1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_034935399.1 3 KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism" XP_034940443.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_034934720.1 5 MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_034943154.1 9 MetaCyc: PWY-7411;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_034946609.1 18 MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I" XP_034950219.1 7 Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133 "Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1" XP_034941351.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_034936433.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034943722.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_034941075.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034941304.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034937113.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034949171.1 17 Reactome: R-HSA-113501;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-6804114;Reactome: R-HSA-111448;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-69202;Reactome: R-HSA-2559580;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of NOXA and translocation to mitochondria";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin E associated events during G1/S transition";"Oxidative Stress Induced Senescence";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_034938349.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034937399.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034943395.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034936144.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034939029.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_034943306.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034944440.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis" XP_034938924.1 9 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation" XP_034942397.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_034941320.1 13 MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_034943499.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034935276.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_034947387.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_034941971.1 16 Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034950146.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_034941327.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348 "Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex" XP_034941405.1 52 Reactome: R-HSA-168325;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-76061;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-1834949;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-167161 "Viral Messenger RNA Synthesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Cytosolic sensors of pathogen-associated DNA";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"HIV Transcription Initiation" XP_034952727.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034937460.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034937292.1 3 Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193 "Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_034935196.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519 "Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression" XP_034938869.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_034936562.1 6 MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-6731;MetaCyc: PWY-5941;Reactome: R-HSA-70221 "Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation III";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)" XP_034933852.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034951444.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034945735.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_034933994.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034944570.1 6 Reactome: R-HSA-5609978;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370 "Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Galactose catabolism" XP_034942961.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955 "Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_034952749.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_034933841.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_034951333.1 3 Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis" XP_034947567.1 7 MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;Reactome: R-HSA-70635;MetaCyc: PWY-4984;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31 "L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Urea cycle";"Urea cycle";"Arginine biosynthesis";"Canavanine degradation" XP_034950285.1 7 KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-7282 "Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_034939380.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_034950288.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034943300.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_034939007.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034943194.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034936322.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034937452.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-3371571 "CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation" XP_034946679.1 29 Reactome: R-HSA-6803204;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-69541;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5693565;Reactome: R-HSA-6796648;Reactome: R-HSA-6804760;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-349425;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;KEGG: 04926+2.7.11.1 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Human papillomavirus infection";"mTOR signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Stabilization of p53";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Methylation";"Human immunodeficiency virus 1 infection";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Thermogenesis";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Relaxin signaling pathway" XP_034936976.1 6 Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-912446;Reactome: R-HSA-5358606 "Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_034945107.1 5 Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012 "Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034940851.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034943956.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706 "Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034952439.1 8 Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-141444 "SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_034943550.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_034948334.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_034944458.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II" XP_034949096.1 4 MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49 "Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway" XP_034952520.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_034936236.1 26 Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813 "Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Separation of Sister Chromatids" XP_034941205.1 4 MetaCyc: PWY-4261;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism" XP_034943326.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034945791.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_034948972.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034950323.1 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_034938307.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_034941024.1 11 MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7124;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-7268 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Ethylene biosynthesis V (engineered)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_034939401.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034950512.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034946204.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034943274.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034934240.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-3928662 "Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"EPHB-mediated forward signaling" XP_034950518.1 5 MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7204 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)" XP_034942445.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_034943513.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs" XP_034935348.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events" XP_034940850.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034936372.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034934501.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034942906.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034952457.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034943581.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034936360.1 3 MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96 "Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis" XP_034948290.1 2 Reactome: R-HSA-8849473;Reactome: R-HSA-6791226 "PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034941126.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724 "Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_034942937.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_034941348.1 7 Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-110362;Reactome: R-HSA-5696395 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER" XP_034944880.1 11 Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_034942501.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_034946512.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_034938769.1 8 Reactome: R-HSA-209905;MetaCyc: PWY-6133;MetaCyc: PWY-3581;KEGG: 00350+1.14.16.2;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049 "Catecholamine biosynthesis";"(S)-reticuline biosynthesis II";"(S)-reticuline biosynthesis I";"Tyrosine metabolism";"Folate biosynthesis";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II" XP_034941530.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_034946441.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_034948077.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034941712.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034948512.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_034935802.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_034949365.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_034951019.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034939457.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_034936622.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_034951746.1 9 MetaCyc: PWY-6146;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1 "Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_034943152.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_034944269.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034943799.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034952429.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_034935572.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_034943512.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034941711.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_034938625.1 1 Reactome: R-HSA-419771 "Opsins" XP_034944175.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034939617.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034934636.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_034939596.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034944929.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034947133.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_034940065.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_034943258.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034933626.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_034951141.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034952783.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034939545.1 33 Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly" XP_034938852.1 12 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"G alpha (12/13) signalling events";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034938615.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034949938.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034941548.1 4 Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772 "Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling" XP_034951080.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695 "2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation" XP_034946258.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_034935978.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_034938858.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism" XP_034942960.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948 "Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants" XP_034937605.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_034945805.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_034938829.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034935335.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_034945981.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_034938096.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_034942490.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_034943355.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_034941169.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034947260.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034950995.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034940895.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-168333 "Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_034950357.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_034949649.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034935292.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034950326.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616 "Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication" XP_034937257.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034943500.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034949779.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_034934241.1 24 Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467 "Kinesins";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs" XP_034940757.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_034942502.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_034951337.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_034936169.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034947687.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034940199.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034950396.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_034945301.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034934092.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_034945302.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034939026.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034940414.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034949507.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034951720.1 5 KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034943645.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_034952489.1 8 KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268 "Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism" XP_034942127.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_034935925.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034933662.1 4 Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-156581;Reactome: R-HSA-6790901 "tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation";"rRNA modification in the nucleus and cytosol" XP_034952455.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_034951806.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642 "Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle" XP_034945717.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50 "HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation" XP_034938665.1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells" XP_034943741.1 11 Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-1268020;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-5628897 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Mitochondrial protein import";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"TP53 Regulates Metabolic Genes" XP_034951039.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034950537.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2 "Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism" XP_034939721.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034946749.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034935753.1 5 KEGG: 00680+1.1.1.95;KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95;Reactome: R-HSA-977347;MetaCyc: PWY-8010 "Methane metabolism";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)" XP_034936369.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034951478.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034940459.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034941008.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034938147.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_034938748.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034950392.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_034934810.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034948051.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034941084.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_034939191.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034949496.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034941243.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_034952553.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034942584.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034949599.1 10 MetaCyc: PWY-3821;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2 "D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism" XP_034943087.1 18 Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783 "Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation" XP_034945481.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_034940165.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_034949472.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034944878.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_034950719.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_034947356.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_034951485.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034944236.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034936588.1 11 Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795 "ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling" XP_034952369.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034935436.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034937373.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034950536.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_034938792.1 7 MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis";"Inositol phosphate metabolism" XP_034936851.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034940318.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034949812.1 9 Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066 "EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_034935024.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034942698.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_034939408.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041 "Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_034942958.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034943149.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034937441.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_034936138.1 6 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Biotin metabolism" XP_034934517.1 25 Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434 "Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034936150.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034947050.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034945371.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034936581.1 6 KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820 "Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)" XP_034941289.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034939396.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_034936306.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_034951105.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_034936725.1 6 KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-5067;Reactome: R-HSA-3322077;MetaCyc: PWY-7900;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis" XP_034940496.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_034947549.1 60 KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;Reactome: R-HSA-77310;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-6583;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-6944;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17;KEGG: 00362+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00410+4.2.1.17;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-7654;Reactome: R-HSA-77305;KEGG: 00360+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00280+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7216;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;Reactome: R-HSA-77348;Reactome: R-HSA-77346;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-5177;MetaCyc: PWY-1361;Reactome: R-HSA-77350;MetaCyc: PWY-6945;Reactome: R-HSA-77288;KEGG: 00623+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17;KEGG: 00720+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-6946;MetaCyc: PWY-5109;MetaCyc: PWY-7778;MetaCyc: PWY-5136;Reactome: R-HSA-1482798 "Fatty acid elongation";"Tryptophan metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid elongation";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"Butanoate metabolism";"Propanoate metabolism";"Butanoate metabolism";"Caprolactam degradation";"Lysine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"Benzoate degradation";"Fatty acid salvage";"Tryptophan metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Geraniol degradation";"Methyl tert-butyl ether degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Phenylalanine metabolism";"Aminobenzoate degradation";"Valine, leucine and isoleucine degradation";"Limonene and pinene degradation";"Lysine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol II (engineered)";"Geraniol degradation";"Pyruvate fermentation to hexanol (engineered)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Toluene degradation";"Fatty acid degradation";"Caprolactam degradation";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fermentation to 2-methylbutanoate";"2-methylpropene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Acyl chain remodeling of CL" XP_034940967.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034941788.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_034947073.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034944224.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state" XP_034936359.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation" XP_034937876.1 26 Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813 "Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-mediated anterograde transport";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids" XP_034940338.1 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_034944651.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_034941343.1 56 Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128 "Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling" XP_034936139.1 6 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_034948660.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-9636467 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification" XP_034947835.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_034937071.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034939536.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_034942090.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034944457.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_034944897.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_034951348.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_034945430.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034935896.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034942025.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034939778.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_034945857.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034943392.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034947124.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases" XP_034933711.1 6 MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism" XP_034947562.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_034944642.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034940848.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034948409.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034951133.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes" XP_034949413.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034944057.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034947212.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_034939690.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034951226.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034952638.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034940911.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_034947380.1 4 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)" XP_034933684.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_034952337.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034942238.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034941991.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378 "Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling" XP_034935507.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034951652.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_034952199.1 10 MetaCyc: PWY-5895;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5839;Reactome: R-HSA-2142789;MetaCyc: PWY-5849;MetaCyc: PWY-5844;MetaCyc: PWY-7996 "Menaquinol-13 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I" XP_034946717.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034951654.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation" XP_034951709.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300 "G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_034947589.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_034942347.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_034942768.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034934599.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_034947790.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_034937628.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105 "Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation" XP_034943136.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034945391.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034945969.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_034949943.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949439.1 1 Reactome: R-HSA-6803529 "FGFR2 alternative splicing" XP_034948904.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_034934058.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034947087.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034949486.1 4 KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2 "Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_034937889.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034947059.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism" XP_034940164.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_034952765.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_034939719.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034948616.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034947351.1 3 Reactome: R-HSA-195399;Reactome: R-HSA-114608;Reactome: R-HSA-194313 "VEGF binds to VEGFR leading to receptor dimerization";"Platelet degranulation";"VEGF ligand-receptor interactions" XP_034935080.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_034943646.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_034946897.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034951314.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_034941377.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_034934104.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034946836.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034940081.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829 "SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Aggrephagy";"Chaperone Mediated Autophagy" XP_034936396.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099 "Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling" XP_034946128.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_034949416.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034935907.1 7 Reactome: R-HSA-2559585;Reactome: R-HSA-6804760;Reactome: R-HSA-69541;Reactome: R-HSA-6804757;Reactome: R-HSA-2559580;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880 "Oncogene Induced Senescence";"Regulation of TP53 Activity through Methylation";"Stabilization of p53";"Regulation of TP53 Degradation";"Oxidative Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases" XP_034942914.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_034936587.1 11 Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"PI3K events in ERBB2 signaling" XP_034933986.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034951296.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034943447.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034941409.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "mTORC1-mediated signalling";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_034951058.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034949503.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034949084.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034939588.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034948603.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_034938424.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_034944685.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_034951104.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_034942585.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034940973.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034947485.1 4 Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" XP_034934683.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_034943401.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034943249.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_034936700.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9619483 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Kinesins";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs" XP_034936186.1 10 Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383 "Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion" XP_034952394.1 3 Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12;MetaCyc: PWY-7210 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_034951502.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_034936187.1 10 KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-4661 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_034949099.1 4 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import";"Mitochondrial translation elongation" XP_034946294.1 18 Reactome: R-HSA-70268;MetaCyc: PWY-5046;KEGG: 00260+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-204174;KEGG: 00280+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00010+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-71064;KEGG: 00380+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.8.1.4;Reactome: R-HSA-70895 "Pyruvate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine, serine and threonine metabolism";"Lysine degradation";"Propanoate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Valine, leucine and isoleucine degradation";"Glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Lysine catabolism";"Tryptophan metabolism";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Branched-chain amino acid catabolism" XP_034950111.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_034950373.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_034945503.1 5 KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68 "Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_034946791.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_034938606.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_034936990.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034949975.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034950322.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034952375.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034949459.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_034950557.1 3 KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3 "Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism" XP_034937871.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982 "Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor" XP_034949909.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-6453 "Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis" XP_034942684.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_034941035.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_034944670.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034952377.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034937427.1 4 KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines" XP_034936637.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_034952563.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034950154.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034937414.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034951928.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_034938503.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034950009.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856825 "Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis" XP_034942642.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_034939520.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034943170.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034944664.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_034950193.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_034947681.1 5 KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263 "Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis" XP_034940060.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034949017.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034948397.1 8 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_034947667.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_034948482.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034942576.1 4 MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782861 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)" XP_034937997.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034937118.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034945448.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034938111.1 9 KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" XP_034941220.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828 "MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis" XP_034939333.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034948264.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1169091 "FCERI mediated NF-kB activation";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells" XP_034943416.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_034938873.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_034943568.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_034951244.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034938498.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_034944538.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034944555.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034936933.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping" XP_034949399.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_034935128.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_034948434.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_034942535.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_034939544.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_034945094.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_034935600.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034936853.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034950327.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034939244.1 4 Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975871 "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane" XP_034939915.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_034936103.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_034934342.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034947201.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_034943648.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_034949766.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_034950113.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_034936362.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_034948985.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis" XP_034934378.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034940781.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_034946208.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_034936200.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034939141.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_034934568.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_034933569.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_034941355.1 7 MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7185 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I" XP_034947802.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_034949270.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_034952754.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins" XP_034951638.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034952316.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034949911.1 10 MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15 "Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism" XP_034937644.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_034936313.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_034938457.1 10 MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)" XP_034945280.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034943141.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_034934088.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034945614.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034941722.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034950468.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034939200.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_034950531.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034942292.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_034946102.1 10 Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692 "Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity" XP_034944901.1 6 KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;MetaCyc: PWY-7356;MetaCyc: PWY-6908;MetaCyc: PWY-6898;Reactome: R-HSA-196819 "Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism" XP_034945341.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034945658.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_034951750.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_034950875.1 179 Reactome: R-HSA-9637628;Reactome: R-HSA-6804757;Reactome: R-HSA-2559582;Reactome: R-HSA-8941858;Reactome: R-HSA-450321;Reactome: R-HSA-1169091;Reactome: R-HSA-975957;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-975110;Reactome: R-HSA-937041;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-162588;Reactome: R-HSA-2173795;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5654733;Reactome: R-HSA-69541;Reactome: R-HSA-179409;Reactome: R-HSA-2559580;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-5693565;Reactome: R-HSA-9615710;Reactome: R-HSA-917937;Reactome: R-HSA-2122948;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-2559585;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-400253;Reactome: R-HSA-937039;Reactome: R-HSA-937072;Reactome: R-HSA-110312;Reactome: R-HSA-917729;Reactome: R-HSA-168928;Reactome: R-HSA-9014325;Reactome: R-HSA-168927;Reactome: R-HSA-8856825;Reactome: R-HSA-5675482;Reactome: R-HSA-2173788;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-6804756;Reactome: R-HSA-6781827;Reactome: R-HSA-156827;Reactome: R-HSA-5607764;Reactome: R-HSA-8849469;Reactome: R-HSA-180585;Reactome: R-HSA-2565942;Reactome: R-HSA-174048;Reactome: R-HSA-2644606;Reactome: R-HSA-6782135;Reactome: R-HSA-901032;Reactome: R-HSA-2408557;Reactome: R-HSA-175474;Reactome: R-HSA-156902;Reactome: R-HSA-5689877;Reactome: R-HSA-5658442;Reactome: R-HSA-3785653;Reactome: R-HSA-2467813;Reactome: R-HSA-1253288;Reactome: R-HSA-532668;Reactome: R-HSA-937042;Reactome: R-HSA-5693607;Reactome: R-HSA-174490;Reactome: R-HSA-182971;Reactome: R-HSA-209543;Reactome: R-HSA-5689901;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-205043;Reactome: R-HSA-975144;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-5654727;Reactome: R-HSA-6781823;Reactome: R-HSA-5610785;Reactome: R-HSA-1358803;Reactome: R-HSA-9636383;Reactome: R-HSA-72764;Reactome: R-HSA-2871837;Reactome: R-HSA-192823;Reactome: R-HSA-3134975;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-5656121;Reactome: R-HSA-5357905;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-5675221;Reactome: R-HSA-72706;Reactome: R-HSA-5685942;Reactome: R-HSA-3769402;Reactome: R-HSA-5610783;Reactome: R-HSA-5654732;Reactome: R-HSA-2173791;Reactome: R-HSA-5668541;Reactome: R-HSA-69231;Reactome: R-HSA-4641258;Reactome: R-HSA-8875360;Reactome: R-HSA-936440;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-9013507;Reactome: R-HSA-8876493;Reactome: R-HSA-2672351;Reactome: R-HSA-6807004;Reactome: R-HSA-1295596;Reactome: R-HSA-174113;Reactome: R-HSA-445989;Reactome: R-HSA-977225;Reactome: R-HSA-6804760;Reactome: R-HSA-912631;Reactome: R-HSA-8866654;Reactome: R-HSA-8856828;Reactome: R-HSA-936964;Reactome: R-HSA-4641263;Reactome: R-HSA-174154;Reactome: R-HSA-8863795;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-2894862;Reactome: R-HSA-9646399;Reactome: R-HSA-9013973;Reactome: R-HSA-174178;Reactome: R-HSA-9645460;Reactome: R-HSA-9604323;Reactome: R-HSA-3322077;Reactome: R-HSA-1169408;Reactome: R-HSA-2691232;Reactome: R-HSA-209560;Reactome: R-HSA-180534;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9613829;Reactome: R-HSA-110314;Reactome: R-HSA-5607761;Reactome: R-HSA-1799339;Reactome: R-HSA-168638;Reactome: R-HSA-8939902;Reactome: R-HSA-450302;Reactome: R-HSA-382556;Reactome: R-HSA-975956;Reactome: R-HSA-5696395;Reactome: R-HSA-975163;Reactome: R-HSA-9633012;Reactome: R-HSA-5654726;Reactome: R-HSA-1236382;Reactome: R-HSA-5362768;Reactome: R-HSA-5696397;Reactome: R-HSA-5357956;Reactome: R-HSA-201681;Reactome: R-HSA-8866652;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-2173796;Reactome: R-HSA-9033241;Reactome: R-HSA-69017;Reactome: R-HSA-6782210;Reactome: R-HSA-2122947;Reactome: R-HSA-75815;Reactome: R-HSA-5655862;Reactome: R-HSA-5205685;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-8948747;Reactome: R-HSA-68827;Reactome: R-HSA-2979096;Reactome: R-HSA-1236974 "Modulation by Mtb of host immune system";"Regulation of TP53 Degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of RUNX3 expression and activity";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of NF-kappaB in B cells";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IKK complex recruitment mediated by RIP1";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Budding and maturation of HIV virion";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Negative regulation of FGFR4 signaling";"Stabilization of p53";"APC-Cdc20 mediated degradation of Nek2A";"Oxidative Stress Induced Senescence";"Neddylation";"DNA Damage Recognition in GG-NER";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Late endosomal microautophagy";"Iron uptake and transport";"Activated NOTCH1 Transmits Signal to the Nucleus";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Oncogene Induced Senescence";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Circadian Clock";"IRAK1 recruits IKK complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Translesion synthesis by REV1";"Endosomal Sorting Complex Required For Transport (ESCRT)";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TICAM1, RIP1-mediated IKK complex recruitment";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of necroptotic cell death";"Downregulation of TGF-beta receptor signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Regulation of TP53 Activity through Phosphorylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"L13a-mediated translational silencing of Ceruloplasmin expression";"CLEC7A (Dectin-1) signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Vif-mediated degradation of APOBEC3G";"Regulation of PLK1 Activity at G2/M Transition";"APC/C:Cdc20 mediated degradation of Cyclin B";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Dual incision in TC-NER";"ER Quality Control Compartment (ERQC)";"Selenocysteine synthesis";"Assembly Of The HIV Virion";"Peptide chain elongation";"Josephin domain DUBs";"Regulation of RAS by GAPs";"Myoclonic epilepsy of Lafora";"Separation of Sister Chromatids";"Downregulation of ERBB4 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"IRAK2 mediated activation of TAK1 complex";"Processing of DNA double-strand break ends";"Membrane binding and targetting of GAG proteins";"EGFR downregulation";"p75NTR recruits signalling complexes";"Metalloprotease DUBs";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"NRIF signals cell death from the nucleus";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Negative regulation of FGFR2 signaling";"Formation of TC-NER Pre-Incision Complex";"GLI3 is processed to GLI3R by the proteasome";"Downregulation of ERBB2:ERBB3 signaling";"Prevention of phagosomal-lysosomal fusion";"Eukaryotic Translation Termination";"FCERI mediated NF-kB activation";"Viral mRNA Translation";"Regulation of innate immune responses to cytosolic DNA";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Translesion synthesis by POLI";"Regulation of TNFR1 signaling";"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Negative regulation of MAPK pathway";"GTP hydrolysis and joining of the 60S ribosomal subunit";"HDR through Homologous Recombination (HRR)";"Deactivation of the beta-catenin transactivating complex";"Degradation of GLI2 by the proteasome";"Negative regulation of FGFR3 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TNFR2 non-canonical NF-kB pathway";"Cyclin D associated events in G1";"Degradation of DVL";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulators of DDX58/IFIH1 signaling";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"InlA-mediated entry of Listeria monocytogenes into host cells";"Stimuli-sensing channels";"Negative regulation of MET activity";"Spry regulation of FGF signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Amyloid fiber formation";"Regulation of TP53 Activity through Methylation";"Regulation of signaling by CBL";"E3 ubiquitin ligases ubiquitinate target proteins";"Clathrin-mediated endocytosis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Regulation of FZD by ubiquitination";"APC/C:Cdc20 mediated degradation of Securin";"Downregulation of ERBB2 signaling";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Aggrephagy";"TICAM1-dependent activation of IRF3/IRF7";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of NOTCH4 signaling";"Glycogen synthesis";"ISG15 antiviral mechanism";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NF-kB is activated and signals survival";"Vpu mediated degradation of CD4";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Chaperone Mediated Autophagy";"Recognition of DNA damage by PCNA-containing replication complex";"Dectin-1 mediated noncanonical NF-kB signaling";"SRP-dependent cotranslational protein targeting to membrane";"NOD1/2 Signaling Pathway";"Regulation of RUNX2 expression and activity";"activated TAK1 mediates p38 MAPK activation";"ABC-family proteins mediated transport";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of Incision Complex in GG-NER";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Negative regulation of FGFR1 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TNFR1-induced NFkappaB signaling pathway";"TCF dependent signaling in response to WNT";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Peroxisomal protein import";"CDK-mediated phosphorylation and removal of Cdc6";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NOTCH1 Intracellular Domain Regulates Transcription";"Ubiquitin-dependent degradation of Cyclin D";"Translesion synthesis by POLK";"Pink/Parkin Mediated Mitophagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Regulation of PTEN localization";"CDT1 association with the CDC6:ORC:origin complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"ER-Phagosome pathway" XP_034940200.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034949200.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination" XP_034944027.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_034951194.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_034936575.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_034934223.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_034939885.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034943518.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034941245.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_034948744.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-69481 "Degradation of AXIN";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"G2/M Checkpoints" XP_034948381.1 15 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167243 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery" XP_034941727.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_034945259.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_034946304.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_034934464.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034950805.1 12 MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7817;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599 "Sucrose biosynthesis II";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycogen synthesis";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_034936589.1 11 Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993 "Signaling by ERBB2";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling" XP_034938509.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_034935465.1 7 Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8 "Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_034933934.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_034948642.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_034937868.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034938837.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034943086.1 18 Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783 "Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation" XP_034942487.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_034942276.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034944053.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_034945400.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034951739.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034946778.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_034936326.1 7 Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00010+3.1.3.11;KEGG: 00710+3.1.3.11 "Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms" XP_034952560.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034933885.1 7 MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;MetaCyc: PWY-7818;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213 "Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE" XP_034941471.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034947277.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_034949021.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_034935418.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_034934339.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_034938787.1 14 MetaCyc: PWY-7124;MetaCyc: PWY-1042;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-1622;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-2221;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-5484 "Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Methane metabolism";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_034948808.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034939786.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_034947517.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_034943139.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_034944543.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034936302.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases" XP_034937928.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034948053.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034946302.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_034934054.1 3 KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B "Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates" XP_034946948.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034950765.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034943740.1 4 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_034942818.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3 "Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism" XP_034950087.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_034940108.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_034947382.1 4 Reactome: R-HSA-8849175;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_034944783.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_034952176.1 4 Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48 "Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_034947688.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034943239.1 26 Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-918233;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408 "Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF3-dependent IRF activation pathway";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation" XP_034934107.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034944582.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_034944552.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034945223.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_034951560.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034947306.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034942725.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_034941063.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230 "Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane" XP_034951589.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_034942942.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_034951245.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" XP_034948305.1 9 Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation" XP_034947103.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034941206.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1 "Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)" XP_034943383.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_034942817.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_034952751.1 11 Reactome: R-HSA-74259;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6538 "Purine catabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Purine metabolism";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Caffeine degradation III (bacteria, via demethylation)" XP_034947587.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034951546.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_034936215.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034946551.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_034946166.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_034949977.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_034952363.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_034952239.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892 "tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_034937296.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_034940732.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_034944648.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_034941456.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034947565.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_034948015.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER" XP_034940339.1 3 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_034937865.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034946524.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_034936081.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_034942440.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism" XP_034943487.1 7 Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795 "POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity" XP_034935459.1 7 Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-198323 "Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol" XP_034945287.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_034940962.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034946042.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035 "Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis" XP_034952376.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034941319.1 13 MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-2201;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-7909;KEGG: 00670+6.3.4.3 "Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate" XP_034939197.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_034943687.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_034944656.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_034944868.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity" XP_034943757.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034945470.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_034943211.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946 "Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_034933846.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_034948630.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034948803.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034934087.1 2 KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384 "Pentose phosphate pathway";"Ethanol oxidation" XP_034933611.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034937673.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034948083.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034942189.1 7 MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis" XP_034937151.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034948733.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034942919.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_034935434.1 7 Reactome: R-HSA-2160456;MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1 "Phenylketonuria";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Folate biosynthesis" XP_034951594.1 13 Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-445989 "Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_034946432.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034945596.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034936165.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_034940668.1 33 Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-69231;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-5696395;Reactome: R-HSA-69273;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-72086 "Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of Incision Complex in GG-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping" XP_034938190.1 3 Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096 "MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation" XP_034941916.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-201681 "Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Protein ubiquitination";"TCF dependent signaling in response to WNT" XP_034935045.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034946915.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034937625.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_034942690.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034940932.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_034937917.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_034942964.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948 "Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants" XP_034951034.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034952467.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034946666.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953 "HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation" XP_034947618.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034941302.1 13 Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5 "Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism" XP_034939300.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034940903.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_034941375.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034949077.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034951527.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034944415.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs" XP_034934037.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034937150.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034935616.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC" XP_034943216.1 6 Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-5651801 "Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair" XP_034950533.1 5 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation" XP_034951042.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_034947491.1 4 Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_034935869.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034937647.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034935696.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_034949511.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034934645.1 14 Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210 "Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Polymerase switching";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_034937160.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763 "Regulation of insulin secretion";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation" XP_034936148.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034935768.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_034942005.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_034937866.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034943045.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_034940497.1 26 Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-3371497 "Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_034934213.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034937367.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_034934108.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034937002.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_034939205.1 3 Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831 "ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" XP_034944874.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_034941718.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034944230.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_034952593.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_034950073.1 8 MetaCyc: PWY-7817;Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 04658+3.1.3.16;KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"Cardiolipin biosynthesis I";"Th1 and Th2 cell differentiation";"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway" XP_034945734.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_034937705.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034939276.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_034947571.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_034951246.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034935401.1 3 KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_034939701.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034951439.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034936999.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_034942077.1 20 Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5693607 "Dual Incision in GG-NER";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Processing of DNA double-strand break ends" XP_034934954.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_034952548.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_034946110.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)" XP_034935911.1 20 Reactome: R-HSA-380972;Reactome: R-HSA-166208;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-165159;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04150+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"Macroautophagy";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"mTOR signalling";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Human papillomavirus infection";"HSF1-dependent transactivation";"mTOR signaling pathway" XP_034941527.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_034938910.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane" XP_034933890.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034951999.1 18 Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167238 "Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation" XP_034948099.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_034948432.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_034945505.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_034946905.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034952403.1 4 Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399 "AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors" XP_034940430.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_034945319.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_034938827.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034934477.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_034946987.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034944079.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_034935905.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_034947619.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_034939790.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034941750.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_034952571.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034940768.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_034942632.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034937660.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034951843.1 8 Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-212300 "SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"HCMV Early Events";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA" XP_034944314.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034944962.1 13 KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7222 "Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_034939099.1 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" XP_034937854.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034939017.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034938471.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_034937152.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-112043 "Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events" XP_034936638.1 33 Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-4615885 "SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Mitotic Prometaphase";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins" XP_034945988.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_034947464.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_034935214.1 11 MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;MetaCyc: PWY-8055;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4 "Anandamide biosynthesis II";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism" XP_034935166.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_034943509.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034948729.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_034950520.1 5 MetaCyc: PWY-7204;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_034936904.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034949944.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949836.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034952064.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_034936154.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034937736.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034942179.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_034939586.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034951740.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034935673.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034947211.1 18 MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-6545 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_034952359.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_034944813.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034946440.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_034940431.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_034942558.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_034942602.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_034948573.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034943653.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5628897 "Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes" XP_034934352.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034952699.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_034942419.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880 "TCF dependent signaling in response to WNT";"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Ub-specific processing proteases" XP_034944657.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_034940456.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034934668.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_034942366.1 4 Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519 "Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression" XP_034935863.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_034945272.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_034946790.1 3 Reactome: R-HSA-948021;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_034937594.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_034951657.1 13 Reactome: R-HSA-4420097;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928662 "VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"Thermogenesis";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"EPHB-mediated forward signaling" XP_034945135.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_034940351.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034948582.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034937388.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034949995.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_034945162.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_034950354.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_034944313.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034946672.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_034933940.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_034944221.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_034939473.1 2 KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_034939989.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034934101.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034942631.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034939339.1 10 KEGG: 00330+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41 "Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis" XP_034939292.1 13 KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883 "Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II" XP_034941201.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034942205.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034951009.1 6 KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_034950130.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034936791.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_034944871.1 11 Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_034945290.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_034939568.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_034945303.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_034946613.1 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation" XP_034935527.1 83 Reactome: R-HSA-6811558;Reactome: R-HSA-5654706;Reactome: R-HSA-5654688;Reactome: R-HSA-9028335;Reactome: R-HSA-8875656;Reactome: R-HSA-8856825;Reactome: R-HSA-5663213;Reactome: R-HSA-5654699;Reactome: R-HSA-74751;Reactome: R-HSA-912526;Reactome: R-HSA-5655291;Reactome: R-HSA-5654689;Reactome: R-HSA-210993;Reactome: R-HSA-5654695;Reactome: R-HSA-983695;Reactome: R-HSA-5654710;Reactome: R-HSA-8853338;Reactome: R-HSA-179812;Reactome: R-HSA-2730905;Reactome: R-HSA-1250196;Reactome: R-HSA-9607240;Reactome: R-HSA-354194;Reactome: R-HSA-180336;Reactome: R-HSA-182971;Reactome: R-HSA-8983432;Reactome: R-HSA-5654726;Reactome: R-HSA-1236382;Reactome: R-HSA-109704;Reactome: R-HSA-1433557;Reactome: R-HSA-375165;Reactome: R-HSA-389359;Reactome: R-HSA-9645135;Reactome: R-HSA-9664565;Reactome: R-HSA-5654704;Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-1963640;Reactome: R-HSA-5655253;Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-5654719;Reactome: R-HSA-2029482;Reactome: R-HSA-1257604;Reactome: R-HSA-9027284;Reactome: R-HSA-1250347;Reactome: R-HSA-112412;Reactome: R-HSA-5655302;Reactome: R-HSA-5654732;Reactome: R-HSA-2179392;Reactome: R-HSA-9634285;Reactome: R-HSA-2871809;Reactome: R-HSA-5654720;Reactome: R-HSA-2424491;Reactome: R-HSA-8853334;Reactome: R-HSA-5654700;Reactome: R-HSA-8853659;Reactome: R-HSA-8875360;Reactome: R-HSA-180292;Reactome: R-HSA-74749;Reactome: R-HSA-6807004;Reactome: R-HSA-1433559;Reactome: R-HSA-1839117;Reactome: R-HSA-1963642;Reactome: R-HSA-5637810;Reactome: R-HSA-5654733;Reactome: R-HSA-5654712;Reactome: R-HSA-8851907;Reactome: R-HSA-512988;Reactome: R-HSA-1295596;Reactome: R-HSA-8875555;Reactome: R-HSA-9034864;Reactome: R-HSA-8865999;Reactome: R-HSA-2428933;Reactome: R-HSA-5654693;Reactome: R-HSA-912631;Reactome: R-HSA-2871796;Reactome: R-HSA-9028731;Reactome: R-HSA-167044;Reactome: R-HSA-2219530;Reactome: R-HSA-8856828;Reactome: R-HSA-9026519;Reactome: R-HSA-8851805;Reactome: R-HSA-186763 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FRS-mediated FGFR3 signaling";"SHC-mediated cascade:FGFR1";"Activated NTRK2 signals through PI3K";"MET receptor recycling";"Cargo recognition for clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"SHC-mediated cascade:FGFR2";"Insulin receptor signalling cascade";"Interleukin receptor SHC signaling";"Signaling by FGFR4 in disease";"PI-3K cascade:FGFR1";"Tie2 Signaling";"PI-3K cascade:FGFR2";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PI-3K cascade:FGFR3";"Signaling by FGFR3 point mutants in cancer";"GRB2 events in EGFR signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"SHC1 events in ERBB2 signaling";"FLT3 Signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"SHC1 events in EGFR signaling";"EGFR downregulation";"Interleukin-15 signaling";"Negative regulation of FGFR1 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI3K Cascade";"Signaling by SCF-KIT";"NCAM signaling for neurite out-growth";"CD28 dependent Vav1 pathway";"STAT5 Activation";"Signaling by ERBB2 KD Mutants";"SHC-mediated cascade:FGFR3";"Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"GRB2 events in ERBB2 signaling";"Signaling by FGFR2 in disease";"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"SHC-mediated cascade:FGFR4";"Regulation of actin dynamics for phagocytic cup formation";"PIP3 activates AKT signaling";"Erythropoietin activates RAS";"SHC1 events in ERBB4 signaling";"SOS-mediated signalling";"Signaling by FGFR1 in disease";"Negative regulation of FGFR3 signaling";"EGFR Transactivation by Gastrin";"Constitutive Signaling by Overexpressed ERBB2";"FCERI mediated Ca+2 mobilization";"PI-3K cascade:FGFR4";"DAP12 signaling";"Signaling by FGFR3 fusions in cancer";"FRS-mediated FGFR2 signaling";"RET signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"GAB1 signalosome";"Signal attenuation";"Negative regulation of MET activity";"Regulation of KIT signaling";"Signaling by cytosolic FGFR1 fusion mutants";"PI3K events in ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Negative regulation of FGFR4 signaling";"FRS-mediated FGFR4 signaling";"MET activates PI3K/AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Spry regulation of FGF signaling";"MET activates RAP1 and RAC1";"Activated NTRK3 signals through RAS";"MET activates PTPN11";"SHC-related events triggered by IGF1R";"FRS-mediated FGFR1 signaling";"Regulation of signaling by CBL";"FCERI mediated MAPK activation";"Activated NTRK2 signals through FRS2 and FRS3";"Signalling to RAS";"Constitutive Signaling by Aberrant PI3K in Cancer";"Clathrin-mediated endocytosis";"Activated NTRK2 signals through RAS";"MET activates RAS signaling";"Downstream signal transduction" XP_034941803.1 12 KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_034945783.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes" XP_034934401.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034951367.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_034935716.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_034945516.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034943317.1 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350 "Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism" XP_034937093.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034948887.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_034935751.1 5 KEGG: 00260+1.1.1.95;KEGG: 00270+1.1.1.95;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00680+1.1.1.95 "Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism" XP_034938151.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_034948078.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034942542.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034940872.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257 "G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN" XP_034945240.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034938838.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_034946462.1 44 Reactome: R-HSA-5654727;Reactome: R-HSA-8940973;Reactome: R-HSA-5673001;Reactome: R-HSA-198753;Reactome: R-HSA-444257;Reactome: R-HSA-9635465;Reactome: R-HSA-6802952;Reactome: R-HSA-2871796;Reactome: R-HSA-3371453;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-879415;Reactome: R-HSA-1295596;Reactome: R-HSA-5654726;Reactome: R-HSA-6802946;Reactome: R-HSA-2559580;Reactome: R-HSA-170968;Reactome: R-HSA-375165;Reactome: R-HSA-202670;Reactome: R-HSA-9627069;Reactome: R-HSA-2559585;Reactome: R-HSA-450341;Reactome: R-HSA-982772;Reactome: R-HSA-9649948;Reactome: R-HSA-9634638;Reactome: R-HSA-881907;Reactome: R-HSA-5674135;Reactome: R-HSA-5654733;Reactome: R-HSA-8939211;Reactome: R-HSA-74749;Reactome: R-HSA-162658;Reactome: R-HSA-456926;Reactome: R-HSA-2559582;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-112409;Reactome: R-HSA-8943724;Reactome: R-HSA-6811558;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5675221;Reactome: R-HSA-5668599;Reactome: R-HSA-5654732;Reactome: R-HSA-445144;Reactome: R-HSA-5674499 "Negative regulation of FGFR2 signaling";"RUNX2 regulates osteoblast differentiation";"RAF/MAP kinase cascade";"ERK/MAPK targets";"RSK activation";"Suppression of apoptosis";"Signaling by BRAF and RAF fusions";"FCERI mediated MAPK activation";"Regulation of HSF1-mediated heat shock response";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Advanced glycosylation endproduct receptor signaling";"Spry regulation of FGF signaling";"Negative regulation of FGFR1 signaling";"Signaling by moderate kinase activity BRAF mutants";"Oxidative Stress Induced Senescence";"Frs2-mediated activation";"NCAM signaling for neurite out-growth";"ERKs are inactivated";"Regulation of the apoptosome activity";"Oncogene Induced Senescence";"Activation of the AP-1 family of transcription factors";"Growth hormone receptor signaling";"Signaling downstream of RAS mutants";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"MAP2K and MAPK activation";"Negative regulation of FGFR4 signaling";"ESR-mediated signaling";"Signal attenuation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Thrombin signalling through proteinase activated receptors (PARs)";"Senescence-Associated Secretory Phenotype (SASP)";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"RAF-independent MAPK1/3 activation";"Regulation of PTEN gene transcription";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"mTOR signaling pathway";"Negative regulation of MAPK pathway";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR3 signaling";"Signal transduction by L1";"Negative feedback regulation of MAPK pathway" XP_034949827.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68689 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex" XP_034943275.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034936257.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_034950278.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034938832.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034944148.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_034942998.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_034944571.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5668541 "Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway" XP_034947276.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_034936573.1 14 MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51 "Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism" XP_034941144.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034944243.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_034952147.1 13 Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-437239 "Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Recycling pathway of L1" XP_034950155.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034939296.1 41 Reactome: R-HSA-5654720;Reactome: R-HSA-5654699;Reactome: R-HSA-5654700;Reactome: R-HSA-5654689;Reactome: R-HSA-190370;Reactome: R-HSA-190372;Reactome: R-HSA-5654695;Reactome: R-HSA-5654219;Reactome: R-HSA-5654733;Reactome: R-HSA-190371;Reactome: R-HSA-8853338;Reactome: R-HSA-5654710;Reactome: R-HSA-5654712;Reactome: R-HSA-6811558;Reactome: R-HSA-5654221;Reactome: R-HSA-5654719;Reactome: R-HSA-5654688;Reactome: R-HSA-5654706;Reactome: R-HSA-1257604;Reactome: R-HSA-8851708;Reactome: R-HSA-5655302;Reactome: R-HSA-190377;Reactome: R-HSA-5654732;Reactome: R-HSA-2033514;Reactome: R-HSA-190322;Reactome: R-HSA-2033519;Reactome: R-HSA-1839122;Reactome: R-HSA-2219530;Reactome: R-HSA-5654704;Reactome: R-HSA-5673001;Reactome: R-HSA-5654727;Reactome: R-HSA-5654228;Reactome: R-HSA-5655253;Reactome: R-HSA-190375;Reactome: R-HSA-5654726;Reactome: R-HSA-109704;Reactome: R-HSA-190373;Reactome: R-HSA-5654687;Reactome: R-HSA-1839130;Reactome: R-HSA-5654227;Reactome: R-HSA-5654693 "PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR2";"FRS-mediated FGFR2 signaling";"PI-3K cascade:FGFR1";"FGFR1b ligand binding and activation";"FGFR3c ligand binding and activation";"PI-3K cascade:FGFR2";"Phospholipase C-mediated cascade: FGFR1";"Negative regulation of FGFR4 signaling";"FGFR3b ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"PI-3K cascade:FGFR3";"FRS-mediated FGFR4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR4";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR3 signaling";"PIP3 activates AKT signaling";"Signaling by FGFR2 IIIa TM";"Signaling by FGFR1 in disease";"FGFR2b ligand binding and activation";"Negative regulation of FGFR3 signaling";"FGFR3 mutant receptor activation";"FGFR4 ligand binding and activation";"Activated point mutants of FGFR2";"Signaling by activated point mutants of FGFR1";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC-mediated cascade:FGFR3";"RAF/MAP kinase cascade";"Negative regulation of FGFR2 signaling";"Phospholipase C-mediated cascade, FGFR4";"Signaling by FGFR2 in disease";"FGFR2c ligand binding and activation";"Negative regulation of FGFR1 signaling";"PI3K Cascade";"FGFR1c ligand binding and activation";"Downstream signaling of activated FGFR1";"Signaling by activated point mutants of FGFR3";"Phospholipase C-mediated cascade, FGFR3";"FRS-mediated FGFR1 signaling" XP_034940764.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_034943168.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034943889.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034951220.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_034938440.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034940896.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-168333 "Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_034949366.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_034944886.1 11 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_034949561.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034948753.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_034947887.1 9 KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-1042 "Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)" XP_034937870.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982 "Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor" XP_034950946.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034947690.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034948054.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034942078.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_034941309.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034946359.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_034937744.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1169091 "FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells" XP_034945248.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_034946143.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_034939065.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2426168 "Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)" XP_034945007.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034945096.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034947793.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034950241.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_034952752.1 10 Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214 "HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins" XP_034939364.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034939345.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_034943649.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_034934160.1 10 Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-202424 "Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Downstream TCR signaling" XP_034949202.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_034951729.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" XP_034935601.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034946291.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_034936402.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping" XP_034941601.1 11 MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_034939458.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_034947841.1 19 KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7198;MetaCyc: PWY-7220;Reactome: R-HSA-380320;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7205 "Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation" XP_034940458.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034942089.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034945286.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_034946114.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7725 "Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_034934307.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_034951555.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_034939602.1 10 KEGG: 05165+2.7.11.1;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5357956;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"T cell receptor signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_034938432.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_034948367.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034941839.1 13 KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7222 "Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_034940990.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_034946431.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034936017.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034943435.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034941702.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23 "Neutrophil degranulation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Galactose metabolism";"Glycosaminoglycan degradation" XP_034943644.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_034948327.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_034941798.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034941009.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034940829.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_034936288.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034943869.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_034939018.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034945388.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034935641.1 3 MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism" XP_034940949.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034951054.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034938881.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_034935882.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034947368.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034934622.1 3 Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation" XP_034951477.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034935965.1 7 KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_034943398.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034936441.1 42 Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-69473;Reactome: R-HSA-3214815;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-9616222;Reactome: R-HSA-3214841;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-912446 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"G2/M DNA damage checkpoint";"HDACs deacetylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Transcriptional regulation of granulopoiesis";"PKMTs methylate histone lysines";"HCMV Late Events";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"Meiotic recombination" XP_034938866.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_034946909.1 4 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines" XP_034951282.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_034934324.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690 "Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events" XP_034939525.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_034940997.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_034940160.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034951136.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes" XP_034939722.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949184.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034945848.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_034944952.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis" XP_034944540.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034948930.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034939101.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034948852.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034951236.1 7 Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-5941 "Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II" XP_034952603.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172 "RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome" XP_034949917.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_034940071.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034939040.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_034946403.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633 "Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_034937048.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_034947127.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_034935063.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034936792.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_034939413.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" XP_034949079.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"HATs acetylate histones" XP_034951161.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034949712.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_034938063.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034945411.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_034941394.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034936116.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034942233.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_034949922.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_034939990.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034942295.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_034946364.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_034951468.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_034946910.1 4 KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16 "Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism" XP_034937708.1 18 MetaCyc: PWY-5913;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7383;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37 "Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism" XP_034938426.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_034951243.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034936312.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" XP_034935294.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034940767.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_034942132.1 17 Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis" XP_034933766.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-141430 "Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_034952050.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034939881.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034944270.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034947120.1 27 KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5358752;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-75815;Reactome: R-HSA-5339716;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-399956;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5467340;Reactome: R-HSA-5610783;Reactome: R-HSA-198323;Reactome: R-HSA-5467348;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-196299 "PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"T41 mutants of beta-catenin aren't phosphorylated";"mTOR signaling pathway";"Human papillomavirus infection";"APC truncation mutants have impaired AXIN binding";"Ubiquitin-dependent degradation of Cyclin D";"Misspliced GSK3beta mutants stabilize beta-catenin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"CRMPs in Sema3A signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Relaxin signaling pathway";"AXIN missense mutants destabilize the destruction complex";"Degradation of GLI2 by the proteasome";"AKT phosphorylates targets in the cytosol";"Truncations of AMER1 destabilize the destruction complex";"Thermogenesis";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"B-WICH complex positively regulates rRNA expression";"Beta-catenin phosphorylation cascade" XP_034948806.1 4 KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9 "Propanoate metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism" XP_034951848.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-176034;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796 "Tat-mediated HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_034944756.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034943047.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_034938794.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_034945380.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_034939535.1 3 KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_034949888.1 4 MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23 "Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism" XP_034939621.1 5 MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_034945214.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796 "mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation" XP_034945935.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_034938059.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_034949914.1 10 MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7587 "Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)" XP_034946831.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034943929.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_034946624.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_034934574.1 17 KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-200425;Reactome: R-HSA-196780;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599 "Pyruvate metabolism";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"Fatty acid biosynthesis";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_034940881.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034935620.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034946991.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_034933679.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_034936301.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_034948719.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_034952723.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034949041.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034946741.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_034951807.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle" XP_034945631.1 6 Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-76005 "Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+" XP_034938365.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034949219.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034934083.1 5 KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;MetaCyc: PWY-5269;MetaCyc: PWY-7817;Reactome: R-HSA-1483148 "Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG" XP_034934835.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_034951027.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_034951800.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781;Reactome: R-HSA-6787450 "Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion" XP_034935743.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_034951294.1 24 Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-8964315 "G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"G-protein activation";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK" XP_034947635.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_034944517.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_034944557.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034942119.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034942521.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_034946536.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_034936243.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis" XP_034948309.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_034943042.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034946511.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-2467813 "Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids" XP_034945645.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034949025.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_034949723.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_034950415.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034933861.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_034944907.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034944149.1 5 MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_034943362.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_034941484.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034944130.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_034934776.1 16 Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-164939;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900 "MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"LDL clearance";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4" XP_034941878.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034934550.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Synthesis of PC";"Neutrophil degranulation" XP_034948772.1 30 Reactome: R-HSA-202424;Reactome: R-HSA-2894862;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-400253;Reactome: R-HSA-5610780;Reactome: R-HSA-1170546;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-2644607;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-917937 "Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Circadian Clock";"Degradation of GLI1 by the proteasome";"Prolactin receptor signaling";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Negative regulation of NOTCH4 signaling";"Neddylation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport" XP_034939530.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_034951359.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034949392.1 10 KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6527;Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-3821;MetaCyc: PWY-6397;Reactome: R-HSA-5609977 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)" XP_034942562.1 3 Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis" XP_034934096.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034939291.1 13 MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" XP_034938624.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_034938060.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034934245.1 10 Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-202424 "Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Downstream TCR signaling" XP_034940495.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide" XP_034939105.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034952420.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878 "Separation of Sister Chromatids";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Intraflagellar transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Macroautophagy";"COPI-mediated anterograde transport" XP_034945619.1 6 KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23 "Galactose metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation" XP_034950764.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034935435.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034942403.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034942616.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_034944146.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034939632.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_034940019.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_034937481.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_034943998.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_034939969.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949787.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034936208.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_034944766.1 6 Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692 "Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"HCMV Early Events";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity" XP_034941373.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_034950474.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-434316;Reactome: R-HSA-399997;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;Reactome: R-HSA-500657;MetaCyc: PWY-6367;Reactome: R-HSA-418217 "Ca2+ pathway";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Presynaptic function of Kainate receptors";"D-myo-inositol-5-phosphate metabolism";"G beta:gamma signalling through PLC beta" XP_034944042.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_034952499.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034943943.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_034940817.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034937771.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034933715.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_034949780.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_034950293.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_034944246.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_034936842.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034952546.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_034952358.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_034933694.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034934332.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034950302.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_034934892.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_034934520.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_034948667.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-180746 "NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Nuclear import of Rev protein" XP_034947607.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034936270.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_034934312.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_034946744.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300 "G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_034945242.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_034951438.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300 "G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_034945551.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_034947072.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034949173.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_034945023.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_034943456.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034946003.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_034952350.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_034936196.1 10 Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880 "Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"Ub-specific processing proteases" XP_034941565.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_034936086.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_034951700.1 13 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_034935952.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_034946623.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism" XP_034936798.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_034942692.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034939373.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_034949385.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_034943746.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034941406.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034951994.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_034939543.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_034942505.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_034942404.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034941263.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion" XP_034942092.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_034948365.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_034937454.1 17 Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis" XP_034937990.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034939823.1 4 Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356 "TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_034937536.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-438066 "Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"RAF activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_034948760.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034952662.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034943433.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034938165.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_034944942.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_034945719.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034950581.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_034939583.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034947365.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_034949347.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034951827.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_034949637.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_034947942.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_034951500.1 5 KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_034942627.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034936345.1 9 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_034946568.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034943143.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway" XP_034949053.1 7 MetaCyc: PWY-7791;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23 "UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_034948531.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_034939203.1 3 MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis" XP_034940522.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_034946206.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_034934220.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034947510.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_034941697.1 2 Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"Formation of apoptosome" XP_034937759.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034952501.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034942382.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_034933991.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034951335.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_034933660.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034947685.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034942677.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_034942770.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034947219.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_034951052.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034951730.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_034946631.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034949485.1 4 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK" XP_034950139.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_034947836.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_034951570.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034947105.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034937455.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)" XP_034942327.1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine" XP_034937864.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034940063.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034946797.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034945453.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_034941645.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034940667.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034945289.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_034946094.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_034951590.1 6 Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5789 "Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_034934218.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034942854.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034939399.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_034937171.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034937142.1 3 Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5685942 "Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)" XP_034949340.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034936730.1 17 Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-202424;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-937042;Reactome: R-HSA-4086398;Reactome: R-HSA-450321;Reactome: R-HSA-5357956;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880 "NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"Downstream TCR signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex";"Ca2+ pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TNFR1-induced NFkappaB signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases" XP_034938149.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_034937976.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_034942252.1 6 KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499 "Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane" XP_034952557.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034934082.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_034943478.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034936214.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_034939486.1 4 Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping" XP_034941012.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034939006.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034944542.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034933610.1 6 KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077;MetaCyc: PWY-7395;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25 "Galactose metabolism";"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_034952447.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_034946007.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription" XP_034937314.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034949717.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034952634.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034945649.1 4 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines" XP_034939046.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034949085.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601 "NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_034937303.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034941631.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_034950807.1 12 MetaCyc: PWY-7817;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527 "Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Glycogen synthesis";"Stachyose degradation" XP_034950894.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Interaction between L1 and Ankyrins" XP_034935715.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_034945646.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_034937748.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_034952753.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins" XP_034952077.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034938616.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034941424.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957 "Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034946066.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_034949883.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483 "Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)" XP_034941232.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_034944014.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958 "Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_034941002.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034947542.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034940837.1 3 Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999 "Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_034940855.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_034941655.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034945757.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_034948987.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_034946469.1 8 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_034948095.1 4 Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-428540 "Nephrin family interactions";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Activation of RAC1" XP_034940968.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034942516.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism" XP_034942644.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034934094.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_034943944.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_034942517.1 4 KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_034946622.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism" XP_034936421.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034947058.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_034935291.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034950662.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034949170.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167243 "RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery" XP_034950560.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_034947649.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034952408.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_034945977.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_034947965.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_034948101.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034950882.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034943616.1 13 MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-7254;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)" XP_034947779.1 3 Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807 "Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_034943713.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034952380.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_034944899.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_034947929.1 9 Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7003 "Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol" XP_034940547.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_034937480.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_034949885.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483 "Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)" XP_034950992.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034941930.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_034951077.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_034950994.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034951884.1 9 Reactome: R-HSA-112043;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204 "PLC beta mediated events";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol" XP_034942620.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_034940653.1 6 Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation" XP_034936308.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_034947170.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034936567.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_034935747.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034941647.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_034946826.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034939940.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_034943407.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_034939591.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034950371.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034943224.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_034937651.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034941411.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034942309.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_034946442.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_034936859.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_034938973.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_034941885.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_034935839.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_034936376.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034940746.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034945441.1 12 KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;KEGG: 00230+2.1.2.2;Reactome: R-HSA-73817;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;Reactome: R-HSA-196780;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9 "One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate" XP_034949478.1 5 MetaCyc: PWY-7082;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Fe(II) oxidation" XP_034937393.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034939161.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_034935928.1 8 MetaCyc: PWY-7199;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556 "Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II" XP_034951292.1 24 Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-420092 "Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors" XP_034943145.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_034945139.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-6798695 "Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation" XP_034942520.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034936417.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034945450.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_034935429.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_034948033.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_034937295.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_034952326.1 8 KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis" XP_034943028.1 4 Reactome: R-HSA-4755583;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108 "Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_034940623.1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5789 "Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_034946322.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_034951835.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_034943448.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034943411.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034949098.1 4 MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism";"Entner-Doudoroff pathway I" XP_034934091.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034942515.1 6 MetaCyc: PWY-4261;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560 "Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism" XP_034938027.1 20 MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-6837 "Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" XP_034940263.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_034948553.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034948581.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034949950.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034951969.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_034941592.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034950310.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034945457.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034945781.1 3 Reactome: R-HSA-447043;Reactome: R-HSA-6798695;Reactome: R-HSA-3928664 "Neurofascin interactions";"Neutrophil degranulation";"Ephrin signaling" XP_034941648.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_034950363.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034939372.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_034942950.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034944900.1 6 KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-7356;MetaCyc: PWY-6908;MetaCyc: PWY-6898 "Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III" XP_034935734.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034947663.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632684 "Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state" XP_034937844.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034951759.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034951051.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034951553.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_034951741.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034944855.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034937448.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA" XP_034941632.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_034947798.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_034946358.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_034941244.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_034950089.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_034940059.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034936370.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034935710.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_034937780.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_034950024.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_034935631.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_034952149.1 27 Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-159236 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034939841.1 11 KEGG: 00230+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-7185;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-6596;MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6607 "Purine metabolism";"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Guanosine nucleotides degradation I" XP_034938289.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_034936849.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034940743.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_034945283.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_034952550.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_034950063.1 8 MetaCyc: PWY-5668;KEGG: 04658+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-7817;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5269;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27 "Cardiolipin biosynthesis I";"Th1 and Th2 cell differentiation";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"T cell receptor signaling pathway";"Cardiolipin biosynthesis II";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism" XP_034944595.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034945738.1 4 Reactome: R-HSA-176974;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Unwinding of DNA";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_034948635.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034933588.1 5 Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109 "Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis" XP_034934958.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_034937120.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034946752.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034950532.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034949440.1 1 Reactome: R-HSA-6803529 "FGFR2 alternative splicing" XP_034941054.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_034946796.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034939625.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_034941145.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034949058.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034941770.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471 "Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB" XP_034947079.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034944652.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_034952500.1 10 MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+5.3.1.1 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms" XP_034951160.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization" XP_034935202.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034939688.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034943002.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_034950221.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_034939503.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034938771.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_034937310.1 4 KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis" XP_034944565.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034938453.1 10 MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484 "Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)" XP_034943196.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_034949213.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034944439.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_034949043.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034935210.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_034937484.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034943922.1 5 Reactome: R-HSA-389661;KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895 "Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism" XP_034940072.1 7 Reactome: R-HSA-71064;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403 "Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)" XP_034948931.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206291;Reactome: R-HSA-6798695 "HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation" XP_034949640.1 7 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_034948824.1 10 Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693568 "Meiotic recombination";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_034934714.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy" XP_034950767.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_034948429.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_034947839.1 19 MetaCyc: PWY-7220;Reactome: R-HSA-380320;Reactome: R-HSA-380270;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-6545 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_034934623.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034938919.1 9 Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_034951218.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_034937949.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034945157.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_034947369.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034946502.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_034946543.1 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034944910.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034942623.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_034941765.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_034938158.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_034944298.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034942231.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_034946665.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome" XP_034943651.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling" XP_034948540.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors" XP_034952328.1 8 KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1 "Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism" XP_034946972.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034939802.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_034945437.1 12 Reactome: R-HSA-73817;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6121;Reactome: R-HSA-196780 "Purine ribonucleoside monophosphate biosynthesis";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"One carbon pool by folate";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Biotin transport and metabolism" XP_034942837.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_034949093.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing" XP_034940685.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034940510.1 5 MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_034939991.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034933884.1 7 MetaCyc: PWY-7818;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-3385 "Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Choline biosynthesis I" XP_034938629.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_034946195.1 20 MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6 "Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism" XP_034935682.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034952558.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034943798.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034940971.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034940567.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_034939930.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_034950287.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034952445.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034941977.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_034942460.1 26 Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-6804114;Reactome: R-HSA-4615885;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-69205;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-1362277;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169 "PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SUMOylation of DNA replication proteins";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"G1/S-Specific Transcription";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis" XP_034952592.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_034940977.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_034933608.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_034933665.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_034943592.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034944677.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_034942609.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_034934216.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034934076.1 10 Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590 "FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling" XP_034937106.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034951254.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_034945647.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_034948953.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_034946767.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_034943937.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034946133.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_034933847.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_034940955.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034937991.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034935612.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_034944408.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_034942218.1 9 Reactome: R-HSA-110329;Reactome: R-HSA-9656255;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-5649702;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-9657050;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Binding";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Defective OGG1 Localization";"Displacement of DNA glycosylase by APEX1" XP_034946396.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_034943354.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_034935561.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_034949411.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034947910.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_034950346.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_034944284.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_034942857.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_034943750.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_034936858.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034947100.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034936075.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034934837.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_034944654.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034937355.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034942223.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034938204.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034941676.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_034947227.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034946433.1 6 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-201722 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex" XP_034944024.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_034944076.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034938775.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162 "RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape" XP_034941146.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034941458.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_034951145.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_034944938.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034945006.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034939451.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034937003.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_034936846.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034945005.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034948103.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_034938250.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_034951063.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation" XP_034943057.1 17 Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6790901 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol" XP_034939406.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism" XP_034948168.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034951354.1 56 Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-450408 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_034951441.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034952008.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_034933632.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034938825.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034948219.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_034940669.1 33 Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-167162;Reactome: R-HSA-8939236;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-69231;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-69202;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167161 "Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"RNA Polymerase II HIV Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Cyclin E associated events during G1/S transition";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation" XP_034934194.1 3 Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639 "Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis" XP_034946196.1 20 MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-5136 "6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)" XP_034936100.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-8934903 "Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy" XP_034943364.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_034940738.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034937994.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034949919.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034935867.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_034935200.1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569 "Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_034947792.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034936667.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034946041.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034950321.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034936047.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034934193.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_034946470.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" XP_034938868.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism" XP_034937706.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034942313.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_034943193.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034949426.1 28 Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-68962;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-5696395;Reactome: R-HSA-69473;Reactome: R-HSA-3371511;Reactome: R-HSA-6782210;Reactome: R-HSA-912446;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862 "Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Formation of Incision Complex in GG-NER";"G2/M DNA damage checkpoint";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Meiotic recombination";"Dual incision in TC-NER";"Translesion synthesis by POLK" XP_034938920.1 9 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis" XP_034938097.1 4 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-71737 "Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Pyrophosphate hydrolysis" XP_034948627.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034935670.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_034941382.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_034936044.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034935359.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034935755.1 6 Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis" XP_034943052.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection" XP_034937137.1 16 Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174084 "APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_034947886.1 30 Reactome: R-HSA-2644607;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-400253;Reactome: R-HSA-983168;Reactome: R-HSA-1170546;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-2894862;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702 "Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Circadian Clock";"Antigen processing: Ubiquitination & Proteasome degradation";"Prolactin receptor signaling";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling" XP_034945615.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034935885.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_034939803.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_034950189.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_034950175.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_034942962.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948 "MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Smooth Muscle Contraction";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants" XP_034935224.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034935107.1 11 MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992;MetaCyc: PWY-3861;Reactome: R-HSA-4043916 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation";"Mannitol degradation II";"Defective MPI causes MPI-CDG (CDG-1b)" XP_034944875.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_034945176.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034939558.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034952150.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_034945244.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_034934494.1 9 Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5674135 "mTOR signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"MAP2K and MAPK activation" XP_034943137.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_034938900.1 6 MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613 "ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation";"Cristae formation" XP_034938728.1 11 Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-8862803;Reactome: R-HSA-2871796;Reactome: R-HSA-8943724;Reactome: R-HSA-1912408;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-450341 "Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FCERI mediated MAPK activation";"Regulation of PTEN gene transcription";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Activation of the AP-1 family of transcription factors" XP_034948902.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation" XP_034937627.1 3 Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627 "O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6" XP_034943357.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_034943305.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034943802.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034945476.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034933838.1 4 KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_034948030.1 7 MetaCyc: PWY-7838;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7839 "Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis" XP_034951066.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034933878.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-879415 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling" XP_034947915.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-9010553 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs" XP_034952177.1 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage" XP_034952170.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185 "Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine metabolism";"UTP and CTP dephosphorylation I" XP_034940841.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events" XP_034952032.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034945984.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724 "Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_034944908.1 19 KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7115;MetaCyc: PWY-5392;MetaCyc: PWY-8086;MetaCyc: PWY-6728;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-7383;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37 "Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism" XP_034939699.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034941326.1 22 Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_034942491.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_034936711.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_034943078.1 6 MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17 "Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism" XP_034939922.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination" XP_034951038.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034944345.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034942610.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_034946635.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_034938556.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034934024.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_034940769.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_034934458.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034950253.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism" XP_034946608.1 12 MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4 "Plasmalogen degradation";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism" XP_034951497.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_034941859.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034947185.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034941505.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034944706.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_034939067.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-5617472 "PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_034940083.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399 "SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy" XP_034943659.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034941714.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034947748.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_034937973.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034940454.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034949844.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_034948649.1 12 MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70263;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13 "1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Methane metabolism" XP_034952220.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034934132.1 17 Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167243;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167158;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-112382;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167290 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Th1 and Th2 cell differentiation";"Pausing and recovery of HIV elongation" XP_034942735.1 14 Reactome: R-HSA-450520;Reactome: R-HSA-165054;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-69273;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "HuR (ELAVL1) binds and stabilizes mRNA";"Rev-mediated nuclear export of HIV RNA";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_034940866.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034935088.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034943517.1 6 Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-912446 "HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination" XP_034942265.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034948868.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034936625.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_034940904.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_034944659.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034943693.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_034945962.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis" XP_034944432.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034942617.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins" XP_034933659.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034937646.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034938133.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_034945550.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_034934655.1 3 KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801 "Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)" XP_034951968.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_034934211.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034950276.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034942225.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034936303.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" XP_034936149.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034950596.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034943856.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034939442.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_034934313.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034937361.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000 "Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF activation" XP_034945788.1 7 KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702 "Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I" XP_034943503.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034947724.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034950471.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_034935852.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_034946124.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034934652.1 3 KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801 "Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)" XP_034936796.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034935347.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681 "Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT" XP_034948709.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034947253.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034938943.1 24 Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-392170 "Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"G-protein activation";"G alpha (z) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12" XP_034944065.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_034951028.1 15 Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-179409 "Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A" XP_034950114.1 10 Reactome: R-HSA-69205;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7199;KEGG: 00670+2.1.1.45;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-3841 "G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleosides salvage";"One carbon pool by folate";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Folate transformations II (plants)" XP_034952327.1 8 KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171 "Streptomycin biosynthesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis" XP_034952223.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034943870.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_034948273.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-180585 "Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G" XP_034938113.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_034947504.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_034950586.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034935219.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034943930.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_034940353.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034942303.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_034933858.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_034952215.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_034939365.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034942401.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034944077.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_034940747.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034936663.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_034935697.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_034945990.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_034949078.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HATs acetylate histones";"HIV Transcription Initiation" XP_034943872.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034945651.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034951802.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642 "Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle" XP_034935195.1 14 Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8934593 "Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity" XP_034939371.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_034951738.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_034935469.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034942679.1 33 Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-5619107 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_034941337.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_034947746.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_034938709.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034946188.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_034938240.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034947168.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034950245.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_034950761.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034952459.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034933855.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-1445148 "Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034941558.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_034942315.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_034943681.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_034934396.1 1 KEGG: 00906+1.23.5.1 "Carotenoid biosynthesis" XP_034939720.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034933953.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_034941777.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034940190.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_034948951.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_034948329.1 6 MetaCyc: PWY-5723;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1 "Rubisco shunt";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_034936504.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_034944477.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_034947652.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_034936028.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_034946936.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034951498.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_034935109.1 11 MetaCyc: PWY-3881;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992;MetaCyc: PWY-3861;Reactome: R-HSA-4043916 "Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation";"Mannitol degradation II";"Defective MPI causes MPI-CDG (CDG-1b)" XP_034949994.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_034937307.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034949939.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034951251.1 6 Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-416993;Reactome: R-HSA-6811438 "COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic" XP_034951202.1 9 Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-69205 "Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription" XP_034938923.1 9 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis" XP_034942356.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034941408.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_034938344.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034943075.1 7 KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;Reactome: R-HSA-77111;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4 "Butanoate metabolism";"Peroxisomal protein import";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Synthesis of Ketone Bodies";"Valine, leucine and isoleucine degradation";"Geraniol degradation" XP_034935433.1 7 KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-7158;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134 "Phenylalanine metabolism";"Phenylketonuria";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"L-tyrosine biosynthesis IV" XP_034942820.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_034947592.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_034939784.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034935370.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034941656.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" XP_034951340.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_034945099.1 5 Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012 "Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034940131.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034933685.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_034934498.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034936862.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034952080.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034939880.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034934105.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034951728.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2" XP_034941248.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034941134.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_034949022.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_034941634.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_034951644.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034945740.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034933658.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034933661.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_034940865.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034943822.1 3 Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_034936580.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034943171.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_034937890.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034934289.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_034950464.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_034943935.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034942816.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3 "Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism" XP_034934592.1 17 KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;Reactome: R-HSA-200425;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5789 "Propanoate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_034951476.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034952242.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_034947650.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034948217.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_034943702.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_034949707.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_034946872.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_034936762.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034950375.1 3 KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis" XP_034937916.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_034942840.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034938020.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034936834.1 10 Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Ub-specific processing proteases";"HATs acetylate histones";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_034937380.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034950336.1 6 MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21 "Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_034946882.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034936321.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034946562.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034945754.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034937082.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034936902.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034950209.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_034950306.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034943450.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034936427.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034949921.1 4 MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59 "Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism" XP_034941469.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034946766.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_034936294.1 12 MetaCyc: PWY-5133;MetaCyc: PWY-7857;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1 "Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Propanoate metabolism";"Chitin degradation to ethanol";"Pyruvate metabolism" XP_034943712.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_034949886.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_034940619.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_034937996.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034948055.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034939278.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034949544.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034944950.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_034940491.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034939331.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034941665.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_034937155.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921 "Role of phospholipids in phagocytosis";"Ion homeostasis";"Regulation of insulin secretion";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation" XP_034952530.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034934139.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_034946654.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_034948939.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034942321.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_034940455.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034945637.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_034934468.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_034935216.1 10 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition" XP_034935391.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_034938011.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034941384.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_034941982.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034942239.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_034941787.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "Hedgehog 'off' state";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_034952370.1 29 Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167161 "Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"HIV Transcription Initiation" XP_034939135.1 16 Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5628897 "Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes" XP_034948249.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_034943318.1 3 Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3 "Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism" XP_034951188.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034937482.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_034942968.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948 "Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants" XP_034951801.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_034941241.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_034938425.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_034945224.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_034951748.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_034941218.1 5 Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-901032 "XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)" XP_034951722.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_034933639.1 11 Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange" XP_034949186.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_034945122.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_034950247.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_034945979.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_034943863.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034948647.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034936534.1 24 Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-9634635;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-165158;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-392451;Reactome: R-HSA-5218921;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-354192;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"RHO GTPases activate PKNs";"Estrogen-stimulated signaling through PRKCZ";"Relaxin signaling pathway";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Activation of AKT2";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"GPVI-mediated activation cascade";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated cell proliferation";"PI3K-Akt signaling pathway";"RSK activation";"Integrin signaling";"mTOR signaling pathway";"Human papillomavirus infection" XP_034940201.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034943432.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034950054.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034940580.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_034949945.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949615.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_034943012.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_034950976.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034944909.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034935431.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" XP_034945089.1 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism" XP_034933906.1 5 MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_034945490.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_034938017.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_034948543.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034947119.1 9 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_034951103.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_034947994.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_034936431.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034944279.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034942249.1 6 Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation" XP_034936134.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034934106.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034938170.1 29 Reactome: R-HSA-6782135;Reactome: R-HSA-3108214;Reactome: R-HSA-5655862;Reactome: R-HSA-3371511;Reactome: R-HSA-6782210;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6783310;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-6804756 "Dual incision in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by POLK";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Meiotic recombination";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Fanconi Anemia Pathway";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation" XP_034941022.1 22 Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716 "S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin" XP_034947446.1 3 Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859 "RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly" XP_034945019.1 10 Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897 "Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes" XP_034940253.1 5 KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" XP_034941506.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_034952418.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034934391.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034940729.1 4 KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis" XP_034936629.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034945742.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034938833.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034936030.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_034934959.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_034944660.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_034952413.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034937090.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034939683.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034946121.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange" XP_034933896.1 25 Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-381771;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-500657 "Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"G-protein activation";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors" XP_034939271.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034949226.1 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034945835.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_034948952.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_034951443.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034944073.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_034951823.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034937483.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_034946850.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_034935226.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034944608.1 6 MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_034944913.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034948394.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_034937929.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_034935449.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression" XP_034943618.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034937657.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034935405.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034940374.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_034951881.1 9 KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" XP_034934635.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_034936623.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_034934142.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034947111.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_034939594.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034939199.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_034952193.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_034943359.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_034938514.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034936854.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034939829.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_034937131.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034949660.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_034942861.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_034945452.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination" XP_034945777.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034936901.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034940897.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_034933860.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_034937157.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-381676 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Regulation of insulin secretion";"Ca2+ pathway";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_034940198.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034947761.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034951357.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_034939430.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034936579.1 9 Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-9608287;Reactome: R-HSA-9608290;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-9630222;Reactome: R-HSA-110331 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Defective MUTYH substrate binding";"Defective MUTYH substrate processing";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective NTHL1 substrate binding";"Cleavage of the damaged purine" XP_034948595.1 24 Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-392170 "G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"G-protein activation";"G alpha (z) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12" XP_034948611.1 11 Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693568 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_034946182.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_034945834.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_034939289.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897 "Estrogen-dependent gene expression";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes" XP_034942305.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518 "COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2" XP_034950210.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_034935935.1 2 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_034933920.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_034944066.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034943451.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034934143.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034942338.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034951057.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034939374.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_034938806.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_034938403.1 16 Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-1250342;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993 "Nuclear signaling by ERBB4";"Signaling by ERBB4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"PI3K events in ERBB4 signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling" XP_034952360.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_034952576.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034949222.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034946710.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034940920.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034944245.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034938532.1 14 MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-8055 "Anandamide biosynthesis I";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE";"Triglyceride biosynthesis";"Synthesis of PC";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis" XP_034940917.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034950513.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034944022.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034936382.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-176187 "Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress" XP_034946832.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034949327.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034945485.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_034939127.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398 "Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Ca2+ pathway" XP_034946216.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_034939587.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034940689.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_034947514.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_034951203.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_034941844.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034943803.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034935388.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034938312.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_034949016.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034933859.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_034938310.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_034943548.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_034942381.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_034951637.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034935126.1 5 MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41 "CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_034943324.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_034952780.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034948599.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034942510.1 6 Reactome: R-HSA-1483166;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;MetaCyc: PWY-4261;MetaCyc: PWY-6118 "Synthesis of PA";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerol-3-phosphate shuttle" XP_034951998.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_034946240.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034936140.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034947090.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_034951747.1 4 MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895 "2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism" XP_034949318.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083 "ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions" XP_034936870.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_034938423.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_034940898.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-168333 "Nuclear import of Rev protein";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_034945821.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034934792.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_034939575.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034951215.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_034938953.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_034943142.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_034939198.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_034940587.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_034950286.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034942024.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034939573.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_034938491.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034947047.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_034938152.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034941376.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_034936380.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034936965.1 6 KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)" XP_034941802.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_034945654.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_034938944.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_034944585.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_034937760.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034935179.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_034938364.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034945546.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_034947135.1 33 Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159236 "Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034940467.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034944536.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034934930.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_034944674.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034943041.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034943502.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_034941279.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034947923.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034949383.1 8 MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_034936375.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034936399.1 4 Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_034952541.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_034949414.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_034938145.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_034940828.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_034945833.1 56 Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling" XP_034950097.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034949940.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034950088.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_034952222.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_034939290.1 13 Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662 "Hyaluronan uptake and degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism" XP_034942194.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034941995.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034941481.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034936841.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034947457.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_034948423.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_034948662.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034951062.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162 "Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape" XP_034946711.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034947532.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_034941799.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034938826.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034937471.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034945752.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034945793.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_034946724.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_034951833.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034952379.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_034937173.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034946906.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_034946309.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034947742.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_034942970.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034937352.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034944553.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_034934630.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" XP_034935057.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034939410.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034945186.1 3 Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857 "Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis" XP_034947646.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034933609.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_034940266.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_034941412.1 6 Reactome: R-HSA-114508;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-2029485;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis";"G alpha (z) signalling events" XP_034943810.1 57 Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276 "Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of AXIN";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_034943155.1 9 MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7385;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA" XP_034942838.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_034947511.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_034951134.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265 "RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes" XP_034940084.1 7 KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11 "Inositol phosphate metabolism";"Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism" XP_034941029.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590 "Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation" XP_034937339.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034941851.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034946443.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_034935320.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_034938317.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034937047.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_034934516.1 25 Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833 "Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly" XP_034948661.1 7 Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36 "Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism" XP_034937133.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034943415.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_034949386.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_034942244.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034947731.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034943911.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034940925.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034943022.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_034939603.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034936323.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034938036.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_034944427.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034945814.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034951197.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_034945232.1 8 Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;MetaCyc: PWY-5723;KEGG: 00710+5.3.1.6;Reactome: R-HSA-5659996;Reactome: R-HSA-6791461;MetaCyc: PWY-1861;KEGG: 00051+5.3.1.6 "Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt";"Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of R5P to RU5P";"RPIA deficiency: failed conversion of RU5P to R5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism" XP_034939128.1 16 Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-426496 "Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs" XP_034951078.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_034951297.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_034946051.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034937461.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034951221.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_034936925.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_034937528.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324 "Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_034944364.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034941997.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_034948330.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034949433.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034950020.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_034940675.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_034946569.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034945168.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_034944181.1 2 MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_034945854.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034934523.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034937869.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982 "Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor" XP_034950977.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034947686.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034944110.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_034943003.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_034935554.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034948841.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_034945141.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034948370.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034937695.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034948754.1 15 Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749 "Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated" XP_034951190.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_034943694.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_034938557.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034942839.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_034936928.1 6 Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neutrophil degranulation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_034943195.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034951036.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034937832.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034952214.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_034937668.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_034937046.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_034938466.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034949273.1 20 Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-69473 "Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"G2/M DNA damage checkpoint" XP_034935637.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_034947033.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_034941490.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034941510.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034952060.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034950362.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034940763.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_034941715.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034946272.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_034949728.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_034940770.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_034941965.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_034945643.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034946136.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_034941650.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_034939654.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_034950151.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_034939954.1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_034938460.1 10 MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042 "1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)" XP_034939845.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_034939934.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034945775.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034946968.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034945458.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034938412.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_034949625.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034942842.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_034942503.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_034943248.1 26 Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-918233 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway" XP_034934230.1 11 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167243 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery" XP_034949390.1 10 MetaCyc: PWY-6527;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-6397;Reactome: R-HSA-5609977 "Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)" XP_034941247.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034947718.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_034951838.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_034947582.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034942257.1 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_034939129.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128 "Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling" XP_034938922.1 9 KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_034947210.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957 "Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034937403.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-9022692 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity" XP_034940320.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_034951749.1 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_034946721.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_034942113.1 12 Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-2979096 "Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_034937208.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034949037.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034951837.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034943961.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_034933910.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034950347.1 26 Reactome: R-HSA-918233;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-210744 "TRAF3-dependent IRF activation pathway";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_034944441.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_034938002.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_034943418.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_034942288.1 14 Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167158 "Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex" XP_034949947.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_034937566.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034949982.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_034942261.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_034949216.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034946244.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Ub-specific processing proteases";"AURKA Activation by TPX2" XP_034934651.1 3 KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590 "Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation" XP_034936754.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_034941869.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034949028.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_034937055.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034950878.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_034952721.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034949195.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034951809.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_034933646.1 7 KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148 "Glycerophospholipid metabolism";"Choline biosynthesis III";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Role of phospholipids in phagocytosis";"Synthesis of PG" XP_034948816.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_034939589.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034943726.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_034933937.1 29 Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-73772 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape" XP_034934529.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-1268020 "Processing of SMDT1";"Mitochondrial protein import" XP_034934398.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034948707.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_034941747.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034949520.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034945409.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034948633.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034934388.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034941978.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_034938932.1 4 Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping" XP_034937466.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034943495.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_034935638.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034952073.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034934787.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_034947789.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_034938840.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism" XP_034934399.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034950380.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20 "Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism" XP_034944954.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034941625.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_034948835.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034949052.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034947702.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_034937634.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_034942514.1 6 MetaCyc: PWY-6118;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Synthesis of PA" XP_034948791.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034941303.1 7 MetaCyc: PWY-6470;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;MetaCyc: PWY-6385;Reactome: R-HSA-446193;MetaCyc: PWY-6471 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)" XP_034945786.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-201722 "Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex" XP_034943801.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034947963.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_034942118.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034950961.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_034935564.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_034948433.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_034935702.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034941748.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_034937779.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_034951829.1 4 MetaCyc: PWY-2781;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315 "Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol" XP_034942045.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_034946461.1 44 Reactome: R-HSA-8939211;Reactome: R-HSA-5654733;Reactome: R-HSA-5674135;Reactome: R-HSA-162658;Reactome: R-HSA-74749;Reactome: R-HSA-9634638;Reactome: R-HSA-9649948;Reactome: R-HSA-982772;Reactome: R-HSA-881907;Reactome: R-HSA-445144;Reactome: R-HSA-5654732;Reactome: R-HSA-5674499;Reactome: R-HSA-5668599;Reactome: R-HSA-5675221;KEGG: 04150+2.7.11.24;Reactome: R-HSA-8943724;Reactome: R-HSA-112409;Reactome: R-HSA-6811558;Reactome: R-HSA-2559582;Reactome: R-HSA-5663213;Reactome: R-HSA-456926;Reactome: R-HSA-2029482;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-879415;Reactome: R-HSA-3371453;Reactome: R-HSA-6802952;Reactome: R-HSA-9635465;Reactome: R-HSA-2871796;Reactome: R-HSA-5673001;Reactome: R-HSA-5654727;Reactome: R-HSA-8940973;Reactome: R-HSA-444257;Reactome: R-HSA-198753;Reactome: R-HSA-202670;Reactome: R-HSA-450341;Reactome: R-HSA-2559585;Reactome: R-HSA-9627069;Reactome: R-HSA-375165;Reactome: R-HSA-170968;Reactome: R-HSA-6802946;Reactome: R-HSA-2559580;Reactome: R-HSA-5654726;Reactome: R-HSA-1295596 "ESR-mediated signaling";"Negative regulation of FGFR4 signaling";"MAP2K and MAPK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signal attenuation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling downstream of RAS mutants";"Growth hormone receptor signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signal transduction by L1";"Negative regulation of FGFR3 signaling";"Negative feedback regulation of MAPK pathway";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of MAPK pathway";"mTOR signaling pathway";"Regulation of PTEN gene transcription";"RAF-independent MAPK1/3 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Senescence-Associated Secretory Phenotype (SASP)";"RHO GTPases Activate WASPs and WAVEs";"Thrombin signalling through proteinase activated receptors (PARs)";"Regulation of actin dynamics for phagocytic cup formation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Advanced glycosylation endproduct receptor signaling";"Regulation of HSF1-mediated heat shock response";"Signaling by BRAF and RAF fusions";"Suppression of apoptosis";"FCERI mediated MAPK activation";"RAF/MAP kinase cascade";"Negative regulation of FGFR2 signaling";"RUNX2 regulates osteoblast differentiation";"RSK activation";"ERK/MAPK targets";"ERKs are inactivated";"Activation of the AP-1 family of transcription factors";"Oncogene Induced Senescence";"Regulation of the apoptosome activity";"NCAM signaling for neurite out-growth";"Frs2-mediated activation";"Signaling by moderate kinase activity BRAF mutants";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR1 signaling";"Spry regulation of FGF signaling" XP_034951031.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034948507.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034939204.1 3 MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807 "Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis" XP_034943519.1 6 Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_034934222.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_034936283.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_034945101.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034939774.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034939584.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034945497.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_034938444.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_034937389.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034948288.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034939472.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_034946142.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_034947885.1 30 Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-2894862;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-1170546;Reactome: R-HSA-400253;Reactome: R-HSA-983168;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2644607;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323 "Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Prolactin receptor signaling";"Circadian Clock";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Neddylation";"Negative regulation of NOTCH4 signaling" XP_034950847.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_034941834.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034939994.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_034948947.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_034939376.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_034940970.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034952766.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_034940691.1 17 Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-69166 "Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate" XP_034944707.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_034940991.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_034937946.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034939279.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034951046.1 40 Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-5578749;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-203927;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"HIV Transcription Initiation";"Transcriptional regulation by small RNAs";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_034935349.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681 "Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT" XP_034948860.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034941733.1 5 Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-376172 "p38MAPK events";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions" XP_034943906.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_034947763.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034936712.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_034947740.1 3 Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517 "cGMP effects";"Ca2+ pathway";"Rap1 signalling" XP_034937092.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034934351.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034944256.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "PKA activation";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_034951195.1 5 MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_034947068.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_034942285.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_034935440.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781 "ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression" XP_034943936.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034943016.1 22 MetaCyc: PWY-5659;KEGG: 00500+5.3.1.9;KEGG: 00520+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-6992;MetaCyc: PWY-7238;MetaCyc: PWY-5054;MetaCyc: PWY-3801;MetaCyc: PWY-6981;MetaCyc: PWY-7347;Reactome: R-HSA-5628897;Reactome: R-HSA-70263;MetaCyc: PWY-7385;Reactome: R-HSA-6798695;KEGG: 00030+5.3.1.9;MetaCyc: PWY-621;MetaCyc: PWY-5384;Reactome: R-HSA-70171;MetaCyc: PWY-622;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5514 "GDP-mannose biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"1,5-anhydrofructose degradation";"Sucrose biosynthesis II";"D-sorbitol biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Chitin biosynthesis";"Sucrose biosynthesis III";"TP53 Regulates Metabolic Genes";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Neutrophil degranulation";"Pentose phosphate pathway";"Sucrose degradation III (sucrose invertase)";"Sucrose degradation IV (sucrose phosphorylase)";"Glycolysis";"Starch biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_034942133.1 4 KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943 "Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates" XP_034936973.1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-912446 "Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination" XP_034949916.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034952781.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034937992.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034942625.1 15 Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-5723;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-1042 "Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)" XP_034942420.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_034937713.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_034951339.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_034937883.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034945221.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_034940821.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_034942036.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_034940954.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034948621.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription" XP_034945751.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_034942728.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034933887.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034939618.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034942304.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_034947692.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034936777.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_034939382.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_034938828.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_034940616.1 6 Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957 "Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_034940494.1 9 MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide" XP_034936293.1 8 Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745 "Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" XP_034947067.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_034945281.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034938362.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034944220.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_034952221.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034939697.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_034935227.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_034943715.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_034943464.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_034937111.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034934135.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-606279 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_034941196.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034948011.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_034936198.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034939785.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_034936249.1 11 Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-400206;Reactome: R-HSA-381340 "PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation" XP_034940364.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_034939440.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_034935679.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034940883.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034941836.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034947483.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034947289.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975957 "rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034946174.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034939528.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_034942283.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_034947580.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034936569.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_034944416.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957 "Peptide chain elongation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034950538.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_034934085.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034947479.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034948041.1 42 Reactome: R-HSA-5625886;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-2559582;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-8936459;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-69473;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-977225;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-9616222;Reactome: R-HSA-110329;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472;Reactome: R-HSA-427359 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"G2/M DNA damage checkpoint";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amyloid fiber formation";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"PKMTs methylate histone lysines";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged pyrimidine";"Meiotic recombination";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression" XP_034937565.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034940680.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_034941420.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034949524.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034934219.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034947997.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_034947866.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_034952334.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034948789.1 11 Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_034939981.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034946246.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_034943325.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034951832.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_034950379.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_034939397.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_034951059.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167161 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation" XP_034952324.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034946896.1 52 Reactome: R-HSA-749476;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-73980;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-76061;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-168325;Reactome: R-HSA-112382;Reactome: R-HSA-167162 "RNA Polymerase III Abortive And Retractive Initiation";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Termination";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"Viral Messenger RNA Synthesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape" XP_034951831.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_034941600.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034936223.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_034945595.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034950391.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_034942504.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_034942740.1 14 Reactome: R-HSA-69273;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-9634638;Reactome: R-HSA-168333;Reactome: R-HSA-2173788;Reactome: R-HSA-450520;Reactome: R-HSA-165054 "Cyclin A/B1/B2 associated events during G2/M transition";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Downregulation of TGF-beta receptor signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Rev-mediated nuclear export of HIV RNA" XP_034944873.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_034937381.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity" XP_034934263.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_034935737.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_034937450.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034939230.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_034948891.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034951718.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034939692.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_034944564.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_034937912.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_034945093.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_034942332.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_034943597.1 6 Reactome: R-HSA-8986944;Reactome: R-HSA-2892247;Reactome: R-HSA-6785807;Reactome: R-HSA-452723;Reactome: R-HSA-3769402;Reactome: R-HSA-2892245 "Transcriptional Regulation by MECP2";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation of pluripotent stem cells";"Deactivation of the beta-catenin transactivating complex";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation" XP_034944223.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_034943455.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_034935356.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034946507.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_034947932.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_034941234.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_034943397.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034951214.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_034936112.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034937803.1 13 Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-167590 "VLDLR internalisation and degradation";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation" XP_034937459.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034943701.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_034940445.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034936571.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034949832.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6804757 "VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation" XP_034939825.1 4 Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356 "Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_034949177.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_034942046.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_034940412.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034946293.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034940555.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_034940125.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_034935606.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034948792.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_034952353.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism" XP_034949188.1 17 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-113501;Reactome: R-HSA-139915;Reactome: R-HSA-1912408;Reactome: R-HSA-69205;Reactome: R-HSA-8953750;Reactome: R-HSA-69231;Reactome: R-HSA-111448;Reactome: R-HSA-6804114;Reactome: R-HSA-9616222;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-2559585;Reactome: R-HSA-1538133;Reactome: R-HSA-2559580;Reactome: R-HSA-1362300 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of PUMA and translocation to mitochondria";"Pre-NOTCH Transcription and Translation";"G1/S-Specific Transcription";"Transcriptional Regulation by E2F6";"Cyclin D associated events in G1";"Activation of NOXA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional regulation of granulopoiesis";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Oncogene Induced Senescence";"G0 and Early G1";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_034936850.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034938469.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034952196.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_034946181.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_034946295.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation" XP_034949094.1 4 MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_034933935.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_034951506.1 5 KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_034951205.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_034940693.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034938066.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034943990.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_034943314.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_034937486.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324 "Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Long-term potentiation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF activation";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_034952419.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034938841.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034936163.1 4 KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_034948681.1 24 Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-392851 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"G alpha (z) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor" XP_034940634.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway" XP_034951761.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_034941407.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034951503.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_034937374.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034942940.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_034943666.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_034946671.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" XP_034943331.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_034934163.1 5 Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-193048 "Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis" XP_034950845.1 3 Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-4608870 "Class B/2 (Secretin family receptors)";"PCP/CE pathway";"Asymmetric localization of PCP proteins" XP_034937395.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034949344.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034941057.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_034933948.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols" XP_034948761.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034949191.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034934154.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_034951945.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_034949442.1 1 Reactome: R-HSA-6803529 "FGFR2 alternative splicing" XP_034934547.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_034934459.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034936716.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034949175.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_034949457.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_034938816.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_034935778.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034934093.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_034948312.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-167162 "TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape" XP_034948552.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034944872.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_034947476.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_034937702.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034948663.1 8 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection" XP_034941764.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034951336.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_034943034.1 4 Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_034937132.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034935044.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_034941127.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis" XP_034937153.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5218921 "Ion homeostasis";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Ca2+ pathway";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation" XP_034946800.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_034939715.1 10 Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1 "RSK activation";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway" XP_034940185.1 13 MetaCyc: PWY-7659;MetaCyc: PWY-7709;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-7182;MetaCyc: PWY-7721 "Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis" XP_034933883.1 7 Reactome: R-HSA-1483191;MetaCyc: PWY-7886;MetaCyc: PWY-3385;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82 "Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism" XP_034952577.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034933712.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_034935937.1 4 Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-983168 "VLDLR internalisation and degradation";"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034947709.1 6 Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-2151201 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis" XP_034941094.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion" XP_034937981.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_034938318.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034940974.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034945288.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_034934660.1 18 MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)" XP_034952336.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034941629.1 11 Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-428890 "RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"Role of ABL in ROBO-SLIT signaling" XP_034937114.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034945160.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_034939335.1 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_034950018.1 7 KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660499 "Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane" XP_034952685.1 27 Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-159236 "Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034936628.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_034947051.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_034934392.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034946112.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)" XP_034941719.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034944755.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" XP_034941786.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034941055.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_034943050.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034949591.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_034945189.1 1 MetaCyc: PWY-6938 "NADH repair" XP_034949462.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_034937642.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_034942633.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034949192.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034944271.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034946956.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_034937154.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-112043 "Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ca2+ pathway";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events" XP_034949949.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949619.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034950534.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_034941073.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034950223.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034942151.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_034933592.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-165159 "HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling" XP_034951565.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034942136.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_034935361.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034939767.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034939504.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034948154.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034941713.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034937397.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034947419.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-168315;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Inhibition of Host mRNA Processing and RNA Silencing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_034934543.1 10 Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-5628897 "Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"TP53 Regulates Metabolic Genes" XP_034940102.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_034946397.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_034951072.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_034944052.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994 "PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_034948946.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_034937654.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034936089.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_034952351.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_034937001.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_034935430.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_034939576.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_034939347.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere" XP_034938207.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_034952526.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_034945227.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148 "RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034940268.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_034950037.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_034952405.1 4 Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399 "AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors" XP_034943976.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034948461.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_034945792.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_034950138.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_034942834.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_034943321.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_034952647.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034937434.1 31 MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-8047;MetaCyc: PWY-5367;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-7858;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-7664;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-6113;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-6799;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-5366;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-75105;MetaCyc: PWY-5142 "Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Bryostatin biosynthesis";"Petroselinate biosynthesis";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Fatty acyl-CoA biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway" XP_034934789.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_034949193.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_034945549.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping" XP_034942482.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052 "Meiotic synapsis";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion" XP_034949594.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_034934221.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034941801.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_034938512.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034952544.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_034947689.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034935962.1 7 KEGG: 00620+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12 "Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis" XP_034939142.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034948814.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_034937073.1 6 Reactome: R-HSA-6787450;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;MetaCyc: PWY-7286 "tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_034934186.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_034936046.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034949441.1 1 Reactome: R-HSA-6803529 "FGFR2 alternative splicing" XP_034934126.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034950010.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_034952497.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_034935046.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034948708.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034944746.1 16 Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-1266695;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-416476;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-1660499 "Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"Interleukin receptor SHC signaling";"RET signaling";"Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Interleukin-7 signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"G alpha (q) signalling events";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane" XP_034952755.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034949380.1 8 MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_034950249.1 13 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis" XP_034950252.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_034951825.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_034934975.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_034944507.1 42 Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-5693571;Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-9616222;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-4551638;Reactome: R-HSA-110330;Reactome: R-HSA-5578749 "G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Meiotic synapsis";"Packaging Of Telomere Ends";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Escape";"Meiotic recombination";"HCMV Late Events";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation by small RNAs" XP_034948588.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_034951102.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_034941011.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_034935619.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_034939533.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034938926.1 9 KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_034942294.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034947447.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760 "snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation" XP_034939297.1 41 Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-5654704;Reactome: R-HSA-1839122;Reactome: R-HSA-190375;Reactome: R-HSA-5654228;Reactome: R-HSA-5655253;Reactome: R-HSA-190373;Reactome: R-HSA-109704;Reactome: R-HSA-5654726;Reactome: R-HSA-5654693;Reactome: R-HSA-5654227;Reactome: R-HSA-5654687;Reactome: R-HSA-1839130;Reactome: R-HSA-190370;Reactome: R-HSA-5654689;Reactome: R-HSA-5654700;Reactome: R-HSA-5654699;Reactome: R-HSA-5654720;Reactome: R-HSA-5654712;Reactome: R-HSA-5654710;Reactome: R-HSA-8853338;Reactome: R-HSA-5654733;Reactome: R-HSA-190371;Reactome: R-HSA-5654695;Reactome: R-HSA-5654219;Reactome: R-HSA-190372;Reactome: R-HSA-1257604;Reactome: R-HSA-8851708;Reactome: R-HSA-5654221;Reactome: R-HSA-5654688;Reactome: R-HSA-5654719;Reactome: R-HSA-5654706;Reactome: R-HSA-6811558;Reactome: R-HSA-190322;Reactome: R-HSA-2033519;Reactome: R-HSA-2033514;Reactome: R-HSA-5654732;Reactome: R-HSA-190377;Reactome: R-HSA-5655302 "Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC-mediated cascade:FGFR3";"Signaling by activated point mutants of FGFR1";"FGFR2c ligand binding and activation";"Phospholipase C-mediated cascade, FGFR4";"Signaling by FGFR2 in disease";"FGFR1c ligand binding and activation";"PI3K Cascade";"Negative regulation of FGFR1 signaling";"FRS-mediated FGFR1 signaling";"Phospholipase C-mediated cascade, FGFR3";"Downstream signaling of activated FGFR1";"Signaling by activated point mutants of FGFR3";"FGFR1b ligand binding and activation";"PI-3K cascade:FGFR1";"FRS-mediated FGFR2 signaling";"SHC-mediated cascade:FGFR2";"PI-3K cascade:FGFR4";"FRS-mediated FGFR4 signaling";"PI-3K cascade:FGFR3";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR4 signaling";"FGFR3b ligand binding and activation";"PI-3K cascade:FGFR2";"Phospholipase C-mediated cascade: FGFR1";"FGFR3c ligand binding and activation";"PIP3 activates AKT signaling";"Signaling by FGFR2 IIIa TM";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR1";"SHC-mediated cascade:FGFR4";"FRS-mediated FGFR3 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FGFR4 ligand binding and activation";"Activated point mutants of FGFR2";"FGFR3 mutant receptor activation";"Negative regulation of FGFR3 signaling";"FGFR2b ligand binding and activation";"Signaling by FGFR1 in disease" XP_034947694.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034948723.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_034949708.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_034942040.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_034933820.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_034944448.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_034937451.1 17 Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5656169 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis" XP_034952430.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_034948989.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034936745.1 5 MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;Reactome: R-HSA-389661 "Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Proline catabolism";"Glyoxylate metabolism and glycine degradation" XP_034947807.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034950243.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_034941917.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034945790.1 7 Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Inositol phosphate metabolism" XP_034947513.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_034944637.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034944784.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_034946649.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_034949189.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034942275.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034951834.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034947463.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_034944997.1 10 Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148 "Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034951007.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162 "Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape" XP_034946864.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034950989.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_034940397.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034945226.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148 "RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034942828.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_034948811.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5871;MetaCyc: PWY-5872;KEGG: 00130+2.1.1.222+2.1.1.64 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_034948943.1 12 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_034937745.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780 "Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome" XP_034942115.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-611105 "Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport" XP_034950980.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034935407.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034933931.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_034936668.1 2 Reactome: R-HSA-8934593;Reactome: R-HSA-69231 "Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1" XP_034940342.1 3 MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581 "Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_034952007.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_034935894.1 16 KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-5749;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.4;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5 "C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Itaconate degradation";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Citrate cycle (TCA cycle)" XP_034938716.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-9603505 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"NTRK3 as a dependence receptor" XP_034942969.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034937032.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034949595.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_034949793.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034940591.1 34 Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159231 "ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_034948901.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034937824.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_034940568.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_034942739.1 14 Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-69273;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5687128 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Cyclin A/B1/B2 associated events during G2/M transition";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MAPK6/MAPK4 signaling" XP_034943840.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_034948418.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_034939412.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034949221.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034947696.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_034940383.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_034939669.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_034951341.1 12 MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550 "Assimilatory sulfate reduction III";"Sulfur metabolism";"Transport and synthesis of PAPS";"Selenate reduction";"Sulfite oxidation III";"Monobactam biosynthesis";"Selenocompound metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se" XP_034940244.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_034951526.1 3 Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_034940976.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_034944869.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_034943417.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_034933807.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events" XP_034949720.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_034946104.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_034936084.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_034945268.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_034940544.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034940381.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_034945364.1 10 Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2197563 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription" XP_034939277.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034935061.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034936702.1 26 Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878 "Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"COPI-mediated anterograde transport" XP_034941061.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-352230 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions";"Amino acid transport across the plasma membrane" XP_034946395.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_034939613.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034937910.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_034941419.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383;Reactome: R-HSA-2206292 "Neutrophil degranulation";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"MPS VII - Sly syndrome" XP_034944584.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_034934466.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_034942284.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_034948388.1 9 Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2871796 "G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"NRAGE signals death through JNK";"FCERI mediated MAPK activation" XP_034940677.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_034943617.1 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-7384;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-7254 "Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"TCA cycle VII (acetate-producers)" XP_034937469.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" XP_034943825.1 5 Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-9646399;Reactome: R-HSA-983168;Reactome: R-HSA-5689877 "Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs" XP_034937867.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034935021.1 29 Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167200 "mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_034937433.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034946712.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_034951707.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_034936962.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_034944588.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_034933938.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_034949375.1 4 Reactome: R-HSA-164944;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-8849471 "Nef and signal transduction";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_034952543.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_034942195.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034936314.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_034938965.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034945207.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034942007.1 11 Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880 "HATs acetylate histones";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases" XP_034936701.1 26 Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_034947292.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034937428.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation" XP_034934200.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034938836.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_034950039.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-4086400 "RHO GTPases Activate Formins";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"PCP/CE pathway" XP_034943905.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_034937977.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_034946565.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034936672.1 6 Reactome: R-HSA-3214841;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "PKMTs methylate histone lysines";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_034934102.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034934055.1 3 MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis" XP_034952309.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_034950091.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_034951836.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_034937462.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300 "Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling" XP_034941080.1 37 Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-204005;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-2132295;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-983170;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377 "Mitotic Prometaphase";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"COPII-mediated vesicle transport";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"MHC class II antigen presentation";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins" XP_034951820.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781 "Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis" XP_034952511.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_034943967.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425 "Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1" XP_034943033.1 4 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_034933606.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_034945477.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9610379 "SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events" XP_034942124.1 9 MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"G alpha (q) signalling events";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" XP_034938024.1 20 MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation" XP_034948942.1 12 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_034943049.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_034951132.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes" XP_034943665.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_034947088.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034941321.1 13 MetaCyc: PWY-2201;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722 "Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Folate polyglutamylation";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate" XP_034940625.1 9 MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7117 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_034940618.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_034948822.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_034935754.1 6 Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440 "Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" XP_034940637.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_034944812.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034947643.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034945684.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_034950866.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_034946108.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199 "(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation" XP_034951342.1 12 KEGG: 00450+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278 "Selenocompound metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Purine metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Selenate reduction";"Monobactam biosynthesis";"Sulfite oxidation III" XP_034948008.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187 "Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_034943040.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034944308.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034944898.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_034934596.1 42 Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-427389;Reactome: R-HSA-3214847;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-2559582;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-69473;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-110329;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-427359;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-171306;Reactome: R-HSA-73772 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HATs acetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"G2/M DNA damage checkpoint";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"PKMTs methylate histone lysines";"Cleavage of the damaged pyrimidine";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"SIRT1 negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Escape" XP_034948587.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034946825.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034944911.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034938839.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034952160.1 5 MetaCyc: PWY-7210;Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism" XP_034942043.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_034936213.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_034952230.1 3 MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450 "Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion" XP_034939734.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034943223.1 8 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis" XP_034947703.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_034951358.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_034935167.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_034941426.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034934095.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_034946566.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034936143.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_034938619.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_034938502.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_034937604.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_034942153.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_034941249.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_034937228.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_034934450.1 7 Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-983168 "Processing of DNA double-strand break ends";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034947230.1 6 KEGG: 00900+4.1.1.33;Reactome: R-HSA-446199;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" XP_034939749.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034946736.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034938064.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034940501.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_034946140.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_034943179.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034952280.1 4 KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I" XP_034944618.1 5 MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560 "Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II" XP_034945201.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034952663.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034948016.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs" XP_034933894.1 25 Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-420092;Reactome: R-HSA-381771;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-8964616 "G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"G alpha (z) signalling events";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42" XP_034948302.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-176409 "Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins" XP_034935924.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034938497.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_034952028.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034951192.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_034939189.1 4 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_034949009.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034950172.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_034944556.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034936250.1 11 Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519 "RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression" XP_034937375.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034949912.1 10 MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15 "Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism" XP_034945158.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034935206.1 3 Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807 "Interleukin-20 family signaling";"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling" XP_034943963.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034948624.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034948925.1 5 KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism" XP_034946967.1 4 KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17 "Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis" XP_034941688.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034937738.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034946860.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_034937447.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA" XP_034935392.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_034941958.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034949206.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034946444.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_034950308.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034941475.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034950148.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_034937277.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_034946472.1 14 MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3661;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation I";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Folate transformations I";"One carbon pool by folate";"Photorespiration ";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_034941324.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034941340.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_034941766.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034935828.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034945582.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034937932.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_034933840.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_034941724.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_034946354.1 11 Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-389948;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-909733;Reactome: R-HSA-877312;Reactome: R-HSA-912694;Reactome: R-HSA-391160;Reactome: R-HSA-432142;Reactome: R-HSA-512988 "GPVI-mediated activation cascade";"Costimulation by the CD28 family";"PD-1 signaling";"PECAM1 interactions";"Interleukin-37 signaling";"Interferon alpha/beta signaling";"Regulation of IFNG signaling";"Regulation of IFNA signaling";"Signal regulatory protein family interactions";"Platelet sensitization by LDL";"Interleukin-3, Interleukin-5 and GM-CSF signaling" XP_034935735.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034942383.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_034948862.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034937788.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034951113.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_034944437.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_034951708.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" XP_034937999.1 7 Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020 "Cristae formation";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"Oxidative phosphorylation";"Mitochondrial protein import" XP_034950283.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034935903.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_034942369.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_034942634.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034951595.1 13 Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837 "IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation" XP_034947257.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034936653.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_034935079.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034945755.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034938990.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453 "Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response" XP_034952355.1 4 KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603 "Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine" XP_034935841.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_034945237.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034947411.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034939686.1 23 Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-381676 "G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G-protein activation";"G alpha (z) signalling events";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_034951435.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1538133 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1" XP_034951808.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844 "Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_034943413.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_034949044.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034933976.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034945547.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_034937344.1 19 Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-936837 "Ion homeostasis";"RAF activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Long-term potentiation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases" XP_034951869.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034944401.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034938533.1 14 MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055 "Anandamide biosynthesis I";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Synthesis of PE";"Triglyceride biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PC";"Anandamide biosynthesis II";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_034937804.1 13 Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-3928665 "VLDLR internalisation and degradation";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells" XP_034936664.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034943043.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034950973.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034948689.1 15 Reactome: R-HSA-1227986;Reactome: R-HSA-9665244;Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9665245;Reactome: R-HSA-9634285;Reactome: R-HSA-9665233;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-9665247;Reactome: R-HSA-9665246;Reactome: R-HSA-1236382;Reactome: R-HSA-9652282;Reactome: R-HSA-9665249;Reactome: R-HSA-9665250 "Signaling by ERBB2";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to AEE788" XP_034947341.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_034947271.1 10 Reactome: R-HSA-977225;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;MetaCyc: PWY-5691;MetaCyc: PWY-7849;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17 "Amyloid fiber formation";"Urate conversion to allantoin II";"Neutrophil degranulation";"Retinoid cycle disease events";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions";"Purine metabolism" XP_034937640.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_034934086.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034934330.1 18 MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7176;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-6545 "Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_034934664.1 24 Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497 "Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"HCMV Early Events";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Cilium Assembly";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_034951380.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034951559.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034940958.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034937054.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034941468.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_034945459.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034944539.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034936852.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034951620.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_034938144.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_034940956.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034947766.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034952458.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034934495.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_034947964.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_034936371.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034943627.1 4 MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism" XP_034945801.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_034950309.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034933702.1 4 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;Reactome: R-HSA-379716 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation" XP_034945471.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034951370.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034947838.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_034942710.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_034934653.1 3 Reactome: R-HSA-156590;MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12 "Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism" XP_034936840.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034934314.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034934872.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034945803.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034948389.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_034950472.1 56 Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603 "Degradation of DVL";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases" XP_034947232.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_034940710.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034937378.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034945733.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_034940014.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_034941033.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034940215.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_034934811.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034934285.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034937251.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_034948592.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" XP_034946125.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034940638.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_034951442.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034940020.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_034937338.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034941414.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_034952104.1 10 MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7587;Reactome: R-HSA-1483166 "Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA" XP_034951910.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4615885 "SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of DNA replication proteins" XP_034952460.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034944234.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_034939614.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034936041.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_034944863.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034941148.1 3 Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_034936290.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034941879.1 3 Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471 "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response" XP_034938921.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation" XP_034940951.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034936705.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_034945688.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034951150.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_034950353.1 14 Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5656169 "Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis" XP_034941752.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_034951280.1 3 KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" XP_034948857.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_034952142.1 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_034952476.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034938627.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_034951608.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034945059.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034944858.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034945888.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034949634.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation" XP_034943032.1 4 KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_034941737.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034946305.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034951850.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648 "RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes" XP_034940426.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034948419.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport" XP_034934310.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_034946301.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_034944151.1 5 MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_034935357.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034943180.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034946941.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034945973.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_034937872.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-438066 "Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation" XP_034949842.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_034938115.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_034944436.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_034943443.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_034937603.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_034950650.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034942010.1 3 Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_034936778.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_034946328.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_034940217.1 7 Reactome: R-HSA-8957275;Reactome: R-HSA-418594;Reactome: R-HSA-114608;Reactome: R-HSA-375276;Reactome: R-HSA-381426;Reactome: R-HSA-416476;Reactome: R-HSA-140837 "Post-translational protein phosphorylation";"G alpha (i) signalling events";"Platelet degranulation";"Peptide ligand-binding receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation" XP_034948080.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_034943396.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034945381.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_034939366.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034943477.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957 "Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034947906.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034934581.1 17 KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599 "Pyruvate metabolism";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency" XP_034938467.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034945156.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_034939628.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034945074.1 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism" XP_034942281.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_034940624.1 9 MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation" XP_034948903.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" XP_034951436.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1538133 "Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1" XP_034935763.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034952493.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_034943940.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_034941267.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034937159.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775 "DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Regulation of insulin secretion";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis" XP_034949034.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034942608.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_034945389.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination" XP_034937523.1 6 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism" XP_034945887.1 8 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Activation of RAC1" XP_034942348.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_034937430.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" XP_034949036.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_034943752.1 8 Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183 "Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand" XP_034939384.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_034948308.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_034945165.1 33 Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531 "Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"tRNA processing in the nucleus" XP_034933984.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034947082.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034935360.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034951064.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_034946835.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034951338.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_034942831.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_034945342.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_034943301.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_034945404.1 12 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167238 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation" XP_034935274.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_034933947.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression" XP_034934849.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034941963.1 3 KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_034949269.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_034939383.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_034944699.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_034944640.1 7 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC" XP_034934224.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_034945815.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034934685.1 18 MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Synthesis of PA";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS" XP_034938464.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034939569.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034946037.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-159231 "SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Nuclear import of Rev protein";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_034942380.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_034951828.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034949889.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_034937641.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_034936824.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_034934507.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism" XP_034940159.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034942541.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034938034.1 16 Reactome: R-HSA-975138;Reactome: R-HSA-209543;Reactome: R-HSA-975110;Reactome: R-HSA-1810476;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-5602498;Reactome: R-HSA-6811558;Reactome: R-HSA-975155;Reactome: R-HSA-9020702;Reactome: R-HSA-5603041;Reactome: R-HSA-1236974;Reactome: R-HSA-5603037;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-3134963 "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"p75NTR recruits signalling complexes";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"RIP-mediated NFkB activation via ZBP1";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"MyD88 deficiency (TLR2/4)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 dependent cascade initiated on endosome";"Interleukin-1 signaling";"IRAK4 deficiency (TLR2/4)";"ER-Phagosome pathway";"IRAK4 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production" XP_034933804.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_034942274.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_034940172.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_034947543.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034948765.1 5 MetaCyc: PWY-7536;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37 "2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism" XP_034934343.1 14 MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7279;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-561 "Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_034941461.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034938865.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_034950050.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_034947378.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034940679.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_034946971.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_034936662.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034946238.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_034935683.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_034941823.1 56 Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-349425 "The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1" XP_034935950.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_034950235.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_034938937.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_034949484.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034950441.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_034937119.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034945587.1 8 MetaCyc: PWY-6545;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_034942619.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_034944451.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_034947719.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_034941457.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034938120.1 9 MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" XP_034937392.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000 "CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF activation" XP_034944231.1 12 Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_034946642.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_034952421.1 14 Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878 "Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Intraflagellar transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Macroautophagy";"COPI-mediated anterograde transport" XP_034934116.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034943073.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034941651.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034942289.1 12 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-73863 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination" XP_034940499.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_034949338.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_034939377.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_034945986.1 14 MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)" XP_034936416.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034939754.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_034942009.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_034948257.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-2219530 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_034934634.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_034935741.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_034948215.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_034944896.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_034939138.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034941374.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_034951719.1 5 KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034936578.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034949578.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034935759.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034939270.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034938169.1 29 Reactome: R-HSA-5696395;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-3108214;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-912446;Reactome: R-HSA-3371511;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-6783310;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-68962 "Formation of Incision Complex in GG-NER";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Meiotic recombination";"HSF1 activation";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Activation of the pre-replicative complex" XP_034946986.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034952579.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_034951473.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034940745.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034941270.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_034945015.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_034948170.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034950173.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_034943723.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034950280.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034937068.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_034952004.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_034951128.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_034950952.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_034952552.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034951429.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034937494.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants" XP_034940141.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_034941113.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_034950676.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_034949325.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034946720.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_034935438.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034950679.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_034942738.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-168333 "MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_034945836.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_034947606.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034937965.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034951082.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization" XP_034945150.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_034951204.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_034945454.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_034943360.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-5610787 "Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Hedgehog 'off' state" XP_034935744.1 3 MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism" XP_034934306.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_034946306.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034949523.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034945831.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_034951972.1 14 MetaCyc: PWY-5078;MetaCyc: PWY-5076;MetaCyc: PWY-5104;MetaCyc: PWY-7767;MetaCyc: PWY-5101;MetaCyc: PWY-5057;MetaCyc: PWY-5108;KEGG: 00270+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00290+2.6.1.42;KEGG: 00770+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42 "L-isoleucine degradation II";"L-leucine degradation III";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"L-valine degradation II";"L-isoleucine biosynthesis V";"Cysteine and methionine metabolism";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine biosynthesis";"Pantothenate and CoA biosynthesis";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation" XP_034947716.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034948608.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034946563.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034949781.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_034942012.1 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-7279;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302 "Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)" XP_034940846.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_034935964.1 7 KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_034945475.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034942155.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_034946714.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_034942328.1 6 MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11 "Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_034951118.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_034944649.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034940690.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_034943454.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034950304.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_034942129.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_034936265.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_034941333.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_034944459.1 4 MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation" XP_034937384.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034935945.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426486 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis" XP_034936292.1 8 Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-3928665 "Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells" XP_034946842.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065676;Reactome: R-HSA-3065678 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" XP_034946392.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_034936727.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_034948311.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176412 "Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C" XP_034934656.1 3 Reactome: R-HSA-156590;MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12 "Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism" XP_034948596.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034949011.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_034939541.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_034942639.1 29 Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5358565;Reactome: R-HSA-6783310;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-68962;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-3108214;Reactome: R-HSA-6782135;Reactome: R-HSA-912446;Reactome: R-HSA-6782210;Reactome: R-HSA-3371511 "Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of the pre-replicative complex";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"SUMOylation of DNA damage response and repair proteins";"Dual incision in TC-NER";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HSF1 activation" XP_034947758.1 17 Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"Human cytomegalovirus infection";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Meiotic synapsis";"mTOR signaling pathway";"Human papillomavirus infection" XP_034938161.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034947916.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957 "mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034937383.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034937305.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034938499.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_034949489.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034948110.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034939816.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis" XP_034948845.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events" XP_034933710.1 6 MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_034937707.1 4 Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8874211 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes" XP_034938029.1 3 MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)" XP_034936101.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852 "Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy" XP_034939398.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_034934436.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_034941843.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034945632.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597 "Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events" XP_034946561.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034940347.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_034940912.1 4 Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4 "Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034949437.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034936864.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034938789.1 14 MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5723;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-5484 "Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Rubisco shunt";"Methane metabolism";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_034935354.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034949218.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034947439.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_034946839.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034937117.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_034933889.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034937340.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034937400.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034950129.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_034945213.1 3 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation" XP_034951168.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_034934103.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034942767.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034952450.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_034948266.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"PPARA activates gene expression" XP_034934513.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034946280.1 3 KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615 "Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation" XP_034938931.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034941880.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_034945741.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034944521.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_034944294.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_034947002.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_034942636.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034947907.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_034947925.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_034943699.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_034939926.1 57 Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664 "Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation" XP_034934056.1 3 MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis" XP_034950457.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_034940166.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_034947784.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_034945780.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_034935762.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034938780.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_034942843.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034938107.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_034937096.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034934553.1 17 Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-6679;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2 "Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis";"Candicidin biosynthesis";"Pyruvate metabolism" XP_034946828.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034942008.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_034941813.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_034936857.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034934779.1 16 Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-164939;Reactome: R-HSA-5140745;Reactome: R-HSA-167590 "Recycling pathway of L1";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation" XP_034935066.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034934665.1 24 Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813 "Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids" XP_034950277.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_034936631.1 6 Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;MetaCyc: PWY-7511 "Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Protein ubiquitination" XP_034943452.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034936605.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_034938951.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_034946782.1 4 KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_034935761.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034946312.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034945804.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034946855.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034948012.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state" XP_034949425.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034952506.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_034934408.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_034945216.1 5 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation" XP_034950463.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_034936185.1 10 MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362 "1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_034950784.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_034948105.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_034947714.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034944340.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_034940734.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_034940029.1 5 Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253 "HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_034938346.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_034942156.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_034936535.1 24 Reactome: R-HSA-9634635;Reactome: R-HSA-5625740;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-165158;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-5218921;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-354192 "Estrogen-stimulated signaling through PRKCZ";"RHO GTPases activate PKNs";"Relaxin signaling pathway";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"Activation of AKT2";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"VEGFR2 mediated cell proliferation";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"mTOR signaling pathway";"Human papillomavirus infection";"RSK activation";"Integrin signaling" XP_034940008.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034938711.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034937334.1 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_034939693.1 7 KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-7255 "Glutathione metabolism";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)" XP_034939313.1 30 Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-2644607;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-2894862;Reactome: R-HSA-2871837;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-400253;Reactome: R-HSA-983168;Reactome: R-HSA-1170546;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-195253 "Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of NOTCH4 signaling";"Neddylation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Circadian Clock";"Antigen processing: Ubiquitination & Proteasome degradation";"Prolactin receptor signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex" XP_034948817.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_034946883.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy" XP_034943010.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034951110.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_034942983.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034941074.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034938875.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_034941590.1 11 Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "HIV Transcription Initiation";"Transcription of the HIV genome";"HATs acetylate histones";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_034942965.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695 "Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation" XP_034941886.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_034950171.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_034937524.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation" XP_034937215.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034938285.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_034941202.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034941151.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034941452.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034933643.1 11 MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055 "Anandamide biosynthesis I";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_034949550.1 57 Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346 "Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis" XP_034945438.1 12 KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;Reactome: R-HSA-73817;Reactome: R-HSA-196780;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6277 "Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"One carbon pool by folate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine ribonucleoside monophosphate biosynthesis";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_034946348.1 11 Reactome: R-HSA-9008059;Reactome: R-HSA-210990;Reactome: R-HSA-389948;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-432142;Reactome: R-HSA-391160;Reactome: R-HSA-912694;Reactome: R-HSA-877312;Reactome: R-HSA-909733 "Interleukin-37 signaling";"PECAM1 interactions";"PD-1 signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Platelet sensitization by LDL";"Signal regulatory protein family interactions";"Regulation of IFNA signaling";"Regulation of IFNG signaling";"Interferon alpha/beta signaling" XP_034944250.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034933814.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" XP_034935372.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" XP_034944044.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_034942152.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_034938500.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_034943085.1 18 KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922 "Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Synthesis of PA";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI" XP_034935906.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_034941114.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034936141.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_034935758.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034942622.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_034950954.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034948301.1 5 Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630 "Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3" XP_034940766.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_034942959.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034940924.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034934788.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_034942438.1 4 Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_034952451.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_034934597.1 42 Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-69473;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-5625886;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-2559582;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-427413;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-427359;Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-110329;Reactome: R-HSA-9616222 "Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"G2/M DNA damage checkpoint";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"NoRC negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"SIRT1 negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"PKMTs methylate histone lysines";"Cleavage of the damaged pyrimidine";"Transcriptional regulation of granulopoiesis" XP_034944663.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034951597.1 13 Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-445989 "Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_034939229.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034934721.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" XP_034942474.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_034952417.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway" XP_034941329.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-6782210 "HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_034939663.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_034946269.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_034949716.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034939314.1 30 Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-2644607;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-2894862;Reactome: R-HSA-202424;Reactome: R-HSA-2122947;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1170546;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-195253 "Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Neddylation";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Downstream TCR signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Prolactin receptor signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Circadian Clock";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex" XP_034946921.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_034943430.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034945010.1 10 Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_034936377.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034936983.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034937877.1 8 Reactome: R-HSA-442982;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Purine metabolism";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors" XP_034951532.1 17 MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7205 "Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation" XP_034942583.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034945321.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_034941383.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_034946558.1 6 MetaCyc: PWY-6174;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;MetaCyc: PWY-922 "Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I" XP_034944876.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_034951344.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034950654.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_034938025.1 20 MetaCyc: PWY-7854;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7338 "Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)" XP_034941070.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034934274.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034934084.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_034941082.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957 "Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034948104.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_034938245.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_034952066.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_034941887.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_034937843.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5362768 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Degradation of AXIN";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_034943953.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_034952281.1 4 MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14 "Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism" XP_034949252.1 11 Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-5668599;MetaCyc: PWY-6352;Reactome: R-HSA-1660517;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1632852;Reactome: R-HSA-109704;Reactome: R-HSA-1660516 "Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Toll Like Receptor 9 (TLR9) Cascade";"RHO GTPases Activate NADPH Oxidases";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Macroautophagy";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane" XP_034938108.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_034952284.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_034947870.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_034940330.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_034942270.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_034937504.1 2 KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_034946321.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_034935462.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_034934631.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-6842 "Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II" XP_034935275.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_034936400.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I" XP_034944272.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034950720.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034941975.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_034952431.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_034934215.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_034951605.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034948613.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_034952141.1 3 KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_034940560.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034938048.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034936378.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034942250.1 6 KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499 "Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane" XP_034951049.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034945140.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation" XP_034947726.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034934742.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_034946320.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_034950806.1 12 MetaCyc: PWY-7343;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9 "UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Glycogen synthesis";"Glycerolipid metabolism" XP_034941402.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034941079.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_034942689.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034949038.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_034948479.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034946422.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_034938918.1 4 Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_034938486.1 13 KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187;Reactome: R-HSA-74259;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7184 "Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine catabolism";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_034951445.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034943288.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034938350.1 8 KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171 "Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis" XP_034950197.1 18 MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4 "Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism" XP_034933799.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_034935197.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-426496 "Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs" XP_034942941.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_034950730.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_034937517.1 2 Reactome: R-HSA-352230;Reactome: R-HSA-442660 "Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters" XP_034946838.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034935364.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72165 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway" XP_034946391.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_034938443.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_034936817.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_034946116.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)" XP_034937376.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034947106.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174048 "Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_034934654.1 3 KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590 "Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation" XP_034945245.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_034948508.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034952146.1 13 Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-167590 "VLDLR internalisation and degradation";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation" XP_034941966.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_034936244.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034947657.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_034946303.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_034952094.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_034942041.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_034938909.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-918233 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway" XP_034948741.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034941728.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_034950188.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034941454.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_034935611.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_034951273.1 3 KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985 "N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose" XP_034936982.1 19 Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-3214858;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-8876725;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6790901 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"RMTs methylate histone arginines";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Protein methylation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol" XP_034947924.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034942544.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_034938427.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_034937177.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034946795.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034948286.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" XP_034942279.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_034945199.1 10 MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171 "Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis" XP_034945961.1 14 MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_034947218.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones" XP_034946718.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034946162.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034941577.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_034937662.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034942355.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034948013.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_034947858.1 5 MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3 "Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_034938422.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_034943059.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320 "Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation" XP_034944013.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins" XP_034939882.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034948203.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787 "Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state" XP_034934476.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034944715.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_034951475.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034945641.1 4 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate" XP_034950147.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_034942832.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_034944315.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034945406.1 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_034943316.1 3 Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3 "Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism" XP_034939689.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034940936.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034949236.1 6 MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_034940152.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_034941183.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476 "Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events" XP_034935748.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034941959.1 33 Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-69273;Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-69231;Reactome: R-HSA-167160;Reactome: R-HSA-69202;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-6781823 "mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex" XP_034938870.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_034950274.1 7 MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_034952725.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_034952584.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_034945855.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034948900.1 5 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_034950423.1 11 MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2 "Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism" XP_034939970.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034951766.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034948897.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_034952397.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034950394.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_034952075.1 3 Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220 "Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins" XP_034936855.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034941494.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex" XP_034935437.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034934591.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_034942439.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_034944701.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_034937874.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Purine metabolism" XP_034934137.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034944278.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034936915.1 14 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167243 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery" XP_034937372.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_034940774.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_034946205.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034952542.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_034938206.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034947764.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034952549.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_034950677.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_034946311.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034943688.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_034949434.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034947071.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034951970.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_034939298.1 15 Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723 "Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation" XP_034947747.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_034938366.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034936724.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_034949719.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034943564.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_034936426.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034942224.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034947268.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_034934629.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" XP_034949033.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034949816.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_034944644.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034949348.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034933682.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_034940000.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway" XP_034946837.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034947293.1 19 Reactome: R-HSA-182971;Reactome: R-HSA-5625970;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-389359;Reactome: R-HSA-5626467;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-5627123;Reactome: R-HSA-114604 "EGFR downregulation";"RHO GTPases activate KTN1";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"CD28 dependent Vav1 pathway";"RHO GTPases activate IQGAPs";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"DCC mediated attractive signaling";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade" XP_034945779.1 3 Reactome: R-HSA-447043;Reactome: R-HSA-3928664;Reactome: R-HSA-6798695 "Neurofascin interactions";"Ephrin signaling";"Neutrophil degranulation" XP_034941751.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_034949203.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_034942112.1 4 Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis" XP_034941918.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787 "Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state" XP_034946549.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034937783.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I" XP_034933802.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_034951576.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_034946084.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_034947622.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034933886.1 7 MetaCyc: PWY-3385;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7818 "Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" XP_034943807.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_034946898.1 52 Reactome: R-HSA-6782210;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-76061;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_034943409.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_034950328.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034934385.1 14 MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-3781;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-611105 "TCA cycle II (plants and fungi)";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport" XP_034940965.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034951804.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_034938343.1 11 KEGG: 00900+5.3.3.2;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-922;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-6174;MetaCyc: PWY-7560 "Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway II (archaea)";"Methylerythritol phosphate pathway II" XP_034951213.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_034945785.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858 "Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines" XP_034945095.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034933821.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_034937116.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_034946884.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-164843 "Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation" XP_034943014.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_034948038.1 42 Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-69473;Reactome: R-HSA-3214815;Reactome: R-HSA-1912408;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-427413;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-171306;Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-110329;Reactome: R-HSA-9616222;Reactome: R-HSA-3214841;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-5693607;Reactome: R-HSA-977225 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"G2/M DNA damage checkpoint";"HDACs deacetylate histones";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"NoRC negatively regulates rRNA expression";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Escape";"Meiotic recombination";"Cleavage of the damaged pyrimidine";"Transcriptional regulation of granulopoiesis";"PKMTs methylate histone lysines";"HCMV Late Events";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Processing of DNA double-strand break ends";"Amyloid fiber formation" XP_034944182.1 2 KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697 "Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)" XP_034938026.1 20 MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-7574 "Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II" XP_034952483.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034935355.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034944354.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_034945029.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_034937781.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_034945593.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034936155.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034946554.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_034942217.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034944068.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034950007.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856825 "Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis" XP_034943015.1 6 Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I" XP_034952570.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034949501.1 16 MetaCyc: PWY-7218;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-2221;Reactome: R-HSA-70263;MetaCyc: PWY-7124 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis";"Ethylene biosynthesis V (engineered)" XP_034945246.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_034950107.1 42 Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-9616222;Reactome: R-HSA-3214841;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-4551638;Reactome: R-HSA-110330;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-5693571;Reactome: R-HSA-73772;Reactome: R-HSA-912446 "RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"HCMV Late Events";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Transcriptional regulation of granulopoiesis";"PKMTs methylate histone lysines";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Meiotic synapsis";"Packaging Of Telomere Ends";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Escape";"Meiotic recombination" XP_034951567.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034939700.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_034937626.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854 "Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis" XP_034936164.1 4 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_034952313.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_034933629.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_034940368.1 27 Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230 "Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Nuclear import of Rev protein";"HCMV Early Events";"HCMV Late Events";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA" XP_034944622.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034936914.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_034944698.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_034952269.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy" XP_034948612.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1" XP_034938416.1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_034934585.1 15 Reactome: R-HSA-381070;Reactome: R-HSA-189451;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-1268020;Reactome: R-HSA-381042;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-6798695 "IRE1alpha activates chaperones";"Heme biosynthesis";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"Mitochondrial protein import";"PERK regulates gene expression";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation" XP_034935671.1 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" XP_034940315.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034937914.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_034939567.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones" XP_034938345.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034940910.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_034939622.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_034947851.1 4 MetaCyc: PWY-7250;Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism" XP_034949190.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034944671.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034941723.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_034946845.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_034948958.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_034940882.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034945137.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695 "Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Neutrophil degranulation" XP_034945756.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_034944176.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034945832.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603 "NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases" XP_034951896.1 56 Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-180534 "GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4" XP_034950848.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_034943491.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034946780.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_034936256.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_034940025.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_034951789.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_034934138.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034937636.1 9 KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744 "Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation" XP_034947995.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_034938109.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_034941477.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034951973.1 14 MetaCyc: PWY-5057;KEGG: 00270+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5076;MetaCyc: PWY-5104;MetaCyc: PWY-7767;MetaCyc: PWY-5101 "L-valine degradation II";"Cysteine and methionine metabolism";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation";"L-isoleucine degradation II";"L-leucine degradation III";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II" XP_034946127.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034939482.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034942277.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034934748.1 11 MetaCyc: PWY-7400;MetaCyc: PWY-7791;MetaCyc: PWY-5154;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3 "L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Pyrimidine metabolism" XP_034943652.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724 "Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription" XP_034936655.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_034934551.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756 "Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Neutrophil degranulation";"Synthesis of PC";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation" XP_034948593.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_034941062.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-352230 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions";"Amino acid transport across the plasma membrane" XP_034946132.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_034941265.1 6 Reactome: R-HSA-8939211;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565 "ESR-mediated signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034952027.1 4 Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_034937371.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695 "Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation" XP_034937493.1 11 Reactome: R-HSA-3560783;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-975634 "Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport" XP_034944623.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034944861.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034942316.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_034951138.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization" XP_034937370.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-6802946 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants" XP_034942387.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_034942161.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_034944487.1 29 Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-6782210 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_034950890.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034947570.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_034941190.1 11 Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_034946190.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_034936054.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_034938908.1 5 Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-936964 "TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_034948100.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_034934251.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442 "EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs" XP_034944669.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_034950170.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_034948815.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_034937606.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_034939170.1 8 Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34 "PPARA activates gene expression";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis" XP_034935218.1 10 Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091 "Downstream TCR signaling";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells" XP_034937149.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121 "Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I" XP_034942340.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034939985.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034941198.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034952192.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_034945989.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_034946211.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation" XP_034947080.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_034942807.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_034940219.1 17 Reactome: R-HSA-74217;MetaCyc: PWY-6644;MetaCyc: PWY-7179-1;MetaCyc: PWY-6620;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-5532;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-4202;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-6608;Reactome: R-HSA-6798695 "Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation II";"Guanine and guanosine salvage";"Purine catabolism";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Purine metabolism";"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Neutrophil degranulation" XP_034944665.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_034946503.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_034942227.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_034950633.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034950729.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_034940380.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_034935052.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034945151.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034942943.1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_034936800.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_034946153.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_034950521.1 5 MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7204 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)" XP_034944961.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_034952631.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034939302.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034936917.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_034948827.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_034943594.1 18 Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6790901 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol" XP_034935823.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034942855.1 3 MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_034946189.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_034946478.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77588 "snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_034937464.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034944241.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034951139.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_034946579.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_034947832.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118 "NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation" XP_034944023.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034934253.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_034937978.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034946075.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6802952 "Neutrophil degranulation";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions" XP_034940998.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034937085.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034936386.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-176187 "CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress" XP_034941192.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-170660 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Adenylate cyclase activating pathway" XP_034939202.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_034943764.1 7 KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2 "Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism" XP_034943828.1 5 Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-193048;MetaCyc: PWY-6129 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis" XP_034951915.1 12 Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression" XP_034937148.1 5 MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_034944362.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_034935315.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034951307.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034947721.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_034949398.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination" XP_034945025.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_034946779.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_034938770.1 4 MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4 "Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis" XP_034943046.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034943011.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034938795.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_034947383.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_034937089.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034937069.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034944610.1 6 KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_034942891.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034945496.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_034945659.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_034945285.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_034950383.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_034938573.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034937772.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_034951724.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_034947773.1 4 Reactome: R-HSA-72203;Reactome: R-HSA-4570464;Reactome: R-HSA-72163;Reactome: R-HSA-9610379 "Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway";"HCMV Late Events" XP_034940765.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_034935571.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_034949987.1 18 MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00330+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7117 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Arginine and proline metabolism";"Novobiocin biosynthesis";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_034942481.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69166 "Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate" XP_034935884.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_034948102.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_034935458.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994 "PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_034936432.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034949049.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_034934584.1 17 Reactome: R-HSA-3371599;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1 "Defective HLCS causes multiple carboxylase deficiency";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Propanoate metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Biotin transport and metabolism";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)" XP_034942453.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_034946653.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_034941425.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_034945069.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034942091.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034947569.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_034938933.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_034951891.1 13 Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Amino acids regulate mTORC1";"mTOR signalling";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_034946207.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_034947407.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034936199.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034939441.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_034947406.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034939687.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_034939120.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_034942511.1 6 KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-4261;MetaCyc: PWY-6952 "Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophosphodiester degradation" XP_034942833.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_034947956.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_034936799.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_034942331.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034939327.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034937510.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000 "Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation" XP_034951369.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034952213.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_034945333.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_034945345.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034938815.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_034951232.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166 "Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate" XP_034950953.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034942339.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034943830.1 5 KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199;Reactome: R-HSA-4755579;Reactome: R-HSA-193048;MetaCyc: PWY-6129 "N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis" XP_034934567.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_034942493.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034940220.1 17 Reactome: R-HSA-74217;MetaCyc: PWY-6644;MetaCyc: PWY-7179-1;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-6611;KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6608;MetaCyc: PWY-5695;Reactome: R-HSA-6798695 "Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation II";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Neutrophil degranulation" XP_034949220.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_034939655.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_034950019.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_034935293.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034940921.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_034942712.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034943278.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034951005.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034950763.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034940737.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034946031.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876 "Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" XP_034946751.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034947274.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-3000171;Reactome: R-HSA-975634;MetaCyc: PWY-7849;Reactome: R-HSA-2453902;MetaCyc: PWY-5691 "Neutrophil degranulation";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Amyloid fiber formation";"Purine metabolism";"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Urate conversion to allantoin III";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I" XP_034946310.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034934995.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_034941842.1 13 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis" XP_034947275.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_034940598.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_034949732.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_034948986.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034950671.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_034943826.1 5 Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-983168 "Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Josephin domain DUBs";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034944561.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_034948767.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034937000.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_034945331.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_034948823.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_034938249.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_034945618.1 6 KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23 "Galactose metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation" XP_034939616.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034949837.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_034938393.1 8 MetaCyc: PWY-7922;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629 "Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_034947541.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034935444.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034934692.1 18 Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783 "Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation" XP_034944266.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-983231 "PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Factors involved in megakaryocyte development and platelet production" XP_034947762.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034937477.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF activation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" XP_034934386.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034941052.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_034946973.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation" XP_034936790.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_034936003.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_034944865.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_034937052.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034944862.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity" XP_034939369.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034952722.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_034937622.1 7 MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism" XP_034940375.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_034948026.1 5 MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012;Reactome: R-HSA-199220;MetaCyc: PWY-6289 "Acyl carrier protein activation";"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism";"Vitamin B5 (pantothenate) metabolism";"Petrobactin biosynthesis" XP_034938456.1 10 MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042 "1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)" XP_034950076.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034940622.1 9 MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7117 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_034935875.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034942835.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_034945971.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_034937302.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034941646.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034948740.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_034942758.1 6 Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712 "FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling" XP_034940487.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034947771.1 4 Reactome: R-HSA-4570464;Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-72163 "SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"mRNA Splicing - Major Pathway" XP_034939935.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_034948396.1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_034938785.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" XP_034945491.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-211733 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"Degradation of AXIN";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_034949948.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949377.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_034947091.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034949597.1 13 KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537 "Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V" XP_034943989.1 4 Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping" XP_034944133.1 4 Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping" XP_034940282.1 7 MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-6614 "Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis" XP_034947920.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_034935371.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_034940666.1 33 Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-69656;Reactome: R-HSA-5696395;Reactome: R-HSA-69273;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-69231;Reactome: R-HSA-6782135 "RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of Incision Complex in GG-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin D associated events in G1";"Dual incision in TC-NER" XP_034952496.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_034945440.1 12 MetaCyc: PWY-6121;Reactome: R-HSA-196780;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6613;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13 "5-aminoimidazole ribonucleotide biosynthesis I";"Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism" XP_034949251.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034945036.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_034945382.1 19 KEGG: 00660+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5172;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-163765;MetaCyc: PWY-6728;MetaCyc: PWY-5392;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00020+2.3.3.8 "C5-Branched dibasic acid metabolism";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Acetyl-coa biosynthesis III (from citrate)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"ChREBP activates metabolic gene expression";"Methylaspartate cycle";"Reductive TCA cycle II";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Citrate cycle (TCA cycle)" XP_034950590.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_034951090.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_034949487.1 5 KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III" XP_034942693.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034936718.1 15 Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-69473 "HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint" XP_034937802.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_034939968.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034943570.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_034939379.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_034945121.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034942480.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69091 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching" XP_034936760.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034949996.1 18 KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6643;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1 "Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Coenzyme M biosynthesis II";"Novobiocin biosynthesis";"Arginine and proline metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism" XP_034936247.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_034943596.1 6 Reactome: R-HSA-452723;Reactome: R-HSA-6785807;Reactome: R-HSA-2892247;Reactome: R-HSA-8986944;Reactome: R-HSA-3769402;Reactome: R-HSA-2892245 "Transcriptional regulation of pluripotent stem cells";"Interleukin-4 and Interleukin-13 signaling";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Transcriptional Regulation by MECP2";"Deactivation of the beta-catenin transactivating complex";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation" XP_034944662.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034943853.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034936087.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_034949424.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_034942004.1 5 Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;MetaCyc: PWY-4983 "ROS and RNS production in phagocytes";"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)" XP_034944658.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_034952340.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034934485.1 6 Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_034937476.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_034935776.1 4 MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1 "UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_034937189.1 19 Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"VLDL assembly";"Chylomicron assembly";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"VLDL clearance";"LDL clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class B Receptors" XP_034951183.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_034936282.1 13 Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-5689896;Reactome: R-HSA-6798695;Reactome: R-HSA-3371511;Reactome: R-HSA-532668;Reactome: R-HSA-8876725;Reactome: R-HSA-5362768 "E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Aggrephagy";"Ovarian tumor domain proteases";"Neutrophil degranulation";"HSF1 activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein methylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_034948787.1 24 Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-380320 "Separation of Sister Chromatids";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes" XP_034950570.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034934350.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034949345.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034935054.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034939776.1 5 MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3 "Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_034944016.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034938112.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_034947908.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034943595.1 6 Reactome: R-HSA-8986944;Reactome: R-HSA-2892247;Reactome: R-HSA-6785807;Reactome: R-HSA-452723;Reactome: R-HSA-2892245;Reactome: R-HSA-3769402 "Transcriptional Regulation by MECP2";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation of pluripotent stem cells";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Deactivation of the beta-catenin transactivating complex" XP_034939043.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034938516.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034935578.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034945317.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends" XP_034949147.1 4 MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87 "Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis" XP_034937474.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034940584.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_034948747.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_034949174.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_034951298.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670 "Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis" XP_034949969.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_034949639.1 7 KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16 "Glutathione metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Arginine and proline metabolism" XP_034951255.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_034947710.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_034952198.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_034935439.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034951076.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_034939190.1 5 Reactome: R-HSA-1237112;Reactome: R-HSA-111458;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069 "Methionine salvage pathway";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Regulation of the apoptosome activity" XP_034951131.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling" XP_034937449.1 3 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA" XP_034936167.1 3 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_034945155.1 12 MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4 "Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism" XP_034940490.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034933891.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_034952648.1 3 Reactome: R-HSA-194313;Reactome: R-HSA-114608;Reactome: R-HSA-195399 "VEGF ligand-receptor interactions";"Platelet degranulation";"VEGF binds to VEGFR leading to receptor dimerization" XP_034951805.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_034942578.1 8 Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938 "Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)" XP_034946430.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034945330.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_034935067.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034945239.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_034940773.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_034951030.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034940050.1 3 Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation" XP_034951237.1 7 MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;Reactome: R-HSA-70221 "Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Starch degradation II";"Glycogen breakdown (glycogenolysis)" XP_034940013.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_034938468.1 33 MetaCyc: PWY-5057;MetaCyc: PWY-6871;MetaCyc: PWY-7798;MetaCyc: PWY-5486;MetaCyc: PWY-5078;MetaCyc: PWY-7396;MetaCyc: PWY-6342;Reactome: R-HSA-71384;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-3162;KEGG: 00680+1.1.1.284;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-7013;MetaCyc: PWY-5079;KEGG: 00626+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00071+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-5082;KEGG: 00980+1.1.1.1;KEGG: 00010+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-7111;MetaCyc: PWY-6802;MetaCyc: PWY-5076;MetaCyc: PWY-1801 "L-valine degradation II";"3-methylbutanol biosynthesis (engineered)";"Protein S-nitrosylation and denitrosylation";"Pyruvate fermentation to ethanol II";"L-isoleucine degradation II";"Butanol and isobutanol biosynthesis (engineered)";"Noradrenaline and adrenaline degradation";"Ethanol oxidation";"alpha-Linolenic acid metabolism";"Chitin degradation to ethanol";"L-tryptophan degradation V (side chain pathway)";"Methane metabolism";"Drug metabolism - cytochrome P450";"Serotonin degradation";"(S)-propane-1,2-diol degradation";"L-phenylalanine degradation III";"Naphthalene degradation";"Chloroalkane and chloroalkene degradation";"Phenylethanol biosynthesis";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to ethanol III";"Fatty acid degradation";"Retinol metabolism";"Acetaldehyde biosynthesis I";"L-methionine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Glycolysis / Gluconeogenesis";"Tyrosine metabolism";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to isobutanol (engineered)";"Salidroside biosynthesis";"L-leucine degradation III";"Formaldehyde oxidation II (glutathione-dependent)" XP_034943457.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034949086.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_034949040.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_034949391.1 10 MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-7328 "D-galactose detoxification";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" XP_034935062.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034939429.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034947551.1 60 MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;Reactome: R-HSA-77305;MetaCyc: PWY-7654;KEGG: 00650+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00281+4.2.1.17;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00362+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-6583;MetaCyc: PWY-6944;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00640+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;Reactome: R-HSA-77310;KEGG: 00930+4.2.1.17;KEGG: 00720+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;Reactome: R-HSA-1482798;MetaCyc: PWY-5136;MetaCyc: PWY-7778;MetaCyc: PWY-5109;MetaCyc: PWY-6946;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;Reactome: R-HSA-77348;Reactome: R-HSA-77288;MetaCyc: PWY-6945;Reactome: R-HSA-77350;MetaCyc: PWY-1361;MetaCyc: PWY-5177;MetaCyc: PWY-7726;MetaCyc: PWY-6883;KEGG: 00592+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7656;MetaCyc: PWY-6863;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00310+4.2.1.17 "Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Geraniol degradation";"Tryptophan metabolism";"Fatty acid salvage";"Benzoate degradation";"Butanoate metabolism";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Lysine degradation";"Caprolactam degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Propanoate metabolism";"Tryptophan metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid elongation";"Fatty acid elongation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Caprolactam degradation";"Carbon fixation pathways in prokaryotes";"Fatty acid degradation";"Toluene degradation";"Acyl chain remodeling of CL";"Fatty acid beta-oxidation II (plant peroxisome)";"2-methylpropene degradation";"Fermentation to 2-methylbutanoate";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Benzoyl-coa degradation I (aerobic)";"Glutaryl-coa degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol II (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Limonene and pinene degradation";"Aminobenzoate degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Lysine degradation" XP_034945837.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection" XP_034939502.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034940761.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_034949032.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034939872.1 5 Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER" XP_034934242.1 24 Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034950374.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_034948369.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection" XP_034935497.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_034946139.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_034948096.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-373753 "Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions" XP_034948166.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_034939456.1 3 MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048 "Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG" XP_034939998.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034944586.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_034933985.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation" XP_034936328.1 7 KEGG: 00710+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00030+3.1.3.11;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263 "Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Methane metabolism";"Gluconeogenesis" XP_034938874.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_034934598.1 17 KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599 "Pyruvate metabolism";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency" XP_034947254.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034946405.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105 "ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation" XP_034945119.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" XP_034935674.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_034947287.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_034950248.1 13 KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902 "Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)" XP_034948675.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034942379.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_034935303.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034947837.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_034949821.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation" XP_034940775.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034943029.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_034937770.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_034949000.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034945794.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_034937354.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_034936383.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_034939585.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034935876.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034942263.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_034951773.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_034947662.1 10 KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-4661;MetaCyc: PWY-6366;MetaCyc: PWY-6365;Reactome: R-HSA-1855204;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6362;Reactome: R-HSA-983231;Reactome: R-HSA-1855167 "Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol" XP_034936048.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034945405.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167243 "RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery" XP_034935083.1 13 MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7222 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_034942703.1 7 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5632684 "Activation of SMO";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state" XP_034946655.1 13 MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" XP_034944735.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-6803207;Reactome: R-HSA-111464 "Transcriptional Regulation by E2F6";"Formation of apoptosome";"Neutrophil degranulation";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_034944232.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_034937979.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling" XP_034951883.1 9 MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system" XP_034948335.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_034951472.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034946849.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_034950360.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_034948052.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034934560.1 12 Reactome: R-HSA-71240;MetaCyc: PWY-6842;MetaCyc: PWY-7901;MetaCyc: PWY-6936;MetaCyc: PWY-801;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7 "Tryptophan catabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism" XP_034939828.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-177929 "Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR" XP_034933636.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-211976 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols" XP_034940406.1 4 Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-162699 "Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose" XP_034936586.1 11 Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631 "Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility" XP_034952131.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_034949328.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034938817.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_034935346.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN" XP_034944026.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_034943410.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_034934393.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034946965.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_034946904.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034937858.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_034943501.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034938205.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_034943453.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034935873.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_034939172.1 8 MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168;MetaCyc: PWY-6174 "Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)" XP_034940620.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism" XP_034933704.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034948518.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation" XP_034936188.1 10 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6361 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)" XP_034944067.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034934778.1 16 Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-164939;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-196025 "LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_034946841.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034938853.1 12 Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Rho GTPase cycle";"DCC mediated attractive signaling";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_034946685.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-191859 "PPARA activates gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly" XP_034946776.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034942391.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_034934329.1 18 MetaCyc: PWY-7205;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227 "CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_034936029.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism" XP_034933888.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034945530.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034945408.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_034939559.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_034941531.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_034940058.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034943429.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034950632.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034951647.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_034939593.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034950453.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034952282.1 4 KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I" XP_034947772.1 4 Reactome: R-HSA-9610379;Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-72203 "HCMV Late Events";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA" XP_034938381.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_034934737.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_034937572.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955 "Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF activation";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_034950055.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034946273.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_034948520.1 5 Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_034942364.1 4 MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_034949275.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_034951760.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034952083.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_034937945.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034943367.1 9 Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-1362277;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" XP_034937252.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034940966.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034939301.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034952225.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034947061.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_034947581.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034950658.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination" XP_034947339.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_034935114.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_034944072.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_034938513.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation" XP_034935065.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_034937499.1 9 Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210 "Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_034944071.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_034951240.1 7 MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;Reactome: R-HSA-70221 "Starch degradation V";"Glycogen degradation II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Starch degradation II";"Glycogen breakdown (glycogenolysis)" XP_034946498.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-6842 "Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II" XP_034945594.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034945802.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034941278.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034937453.1 17 Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-69091 "Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching" XP_034948092.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034945687.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034947202.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_034937502.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity" XP_034942815.1 5 MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3 "Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism" XP_034938363.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034945987.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis" XP_034941423.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_034941529.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_034942269.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_034948218.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_034951101.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034939626.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_034946471.1 14 KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00630+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3661 "One carbon pool by folate";"Photorespiration ";"Folate polyglutamylation";"Metabolism of folate and pterines";"Methane metabolism";"Folate transformations I";"Glyoxylate and dicarboxylate metabolism";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation I" XP_034947477.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034945980.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034939375.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_034951842.1 8 Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580 "PRC2 methylates histones and DNA";"HCMV Early Events";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence" XP_034950372.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_034943069.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_034938831.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_034947060.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_034945689.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034950301.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034943346.1 33 Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-1169408 "Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"HCMV Early Events";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism" XP_034937161.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-381676 "Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_034947952.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_034947566.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_034938290.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034944860.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_034936998.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_034951783.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034942951.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034933765.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174084 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_034945136.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_034937873.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"RAF/MAP kinase cascade" XP_034942629.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034936258.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034940096.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_034946098.1 10 Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-983231 "MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production" XP_034937629.1 3 Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627 "O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6" XP_034943928.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_034934368.1 58 Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-69481 "Degradation of AXIN";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Metalloprotease DUBs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"G2/M Checkpoints" XP_034949217.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034939318.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034946555.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_034945294.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_034933721.1 11 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052 "Ether lipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis" XP_034950225.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034934815.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_034940197.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_034941208.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation" XP_034946157.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_034943134.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_034935936.1 4 Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-983168 "VLDLR internalisation and degradation";"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034943126.1 4 KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis" XP_034947131.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_034942694.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_034936004.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_034934563.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_034936974.1 6 Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-912446 "TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination" XP_034935742.1 3 KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213 "Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE" XP_034939873.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395 "HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER" XP_034948813.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034945474.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_034951295.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines" XP_034939370.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_034945797.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_034947319.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_034948948.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_034942011.1 3 KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_034945284.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_034943700.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_034937933.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_034933717.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_034941476.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383 "Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation" XP_034950224.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034942026.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034937172.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034941532.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_034952124.1 8 MetaCyc: PWY-5723;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;MetaCyc: PWY-1861;Reactome: R-HSA-6791462 "Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P" XP_034934870.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_034952400.1 5 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway" XP_034939552.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_034938263.1 14 MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4 "Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism" XP_034947098.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034934621.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_034950895.1 5 Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_034947258.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034952477.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-606279 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_034950978.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034952162.1 5 KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937 "Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport" XP_034945392.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034946610.1 18 KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1483166 "Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Synthesis of PA" XP_034937857.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_034941200.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040 "G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_034935056.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034943044.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_034944870.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_034944373.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_034952161.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034936674.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE" XP_034949630.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_034940909.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_034941191.1 14 Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-110314 "Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex" XP_034945028.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_034947415.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034947540.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_034945782.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243 "Chromatin modifying enzymes";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034936570.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis" XP_034950187.1 3 MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117 "Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I" XP_034942513.1 6 Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-4261;MetaCyc: PWY-6952 "Triglyceride catabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophosphodiester degradation" XP_034950988.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_034939045.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_034950934.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034935402.1 3 KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_034951231.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243 "Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Neutrophil degranulation";"Synthesis of PC";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034944438.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_034940635.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034935910.1 20 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-166208;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"mTOR signalling";"Regulation of TP53 Degradation";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis" XP_034946062.1 3 MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661 "Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis" XP_034935406.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034936172.1 57 Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-174178 "Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_034951056.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034935295.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_034950098.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_034948886.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_034942076.1 20 Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Polymerase switching";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_034941749.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_034937959.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_034942354.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034946439.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_034951479.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034936847.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034946326.1 30 KEGG: 05165+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-6804758;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-9634638;Reactome: R-HSA-8876198;Reactome: R-HSA-5628897;Reactome: R-HSA-69656;Reactome: R-HSA-199418;Reactome: R-HSA-111447;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-8948751;KEGG: 05163+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-6804759;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-8941332;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-389513;Reactome: R-HSA-69202;Reactome: R-HSA-9614399;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920 "Human papillomavirus infection";"AKT phosphorylates targets in the nucleus";"Regulation of TP53 Activity through Acetylation";"mTOR signaling pathway";"Downregulation of ERBB2:ERBB3 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RAB GEFs exchange GTP for GDP on RABs";"TP53 Regulates Metabolic Genes";"Cyclin A:Cdk2-associated events at S phase entry";"Negative regulation of the PI3K/AKT network";"Activation of BAD and translocation to mitochondria";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Regulation of PTEN stability and activity";"Human cytomegalovirus infection";"AKT-mediated inactivation of FOXO1A";"Regulation of TP53 Activity through Association with Co-factors";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"RUNX2 regulates genes involved in cell migration";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"CTLA4 inhibitory signaling";"Cyclin E associated events during G1/S transition";"Regulation of localization of FOXO transcription factors";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability" XP_034946834.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034952782.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034947644.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034937224.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_034952480.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162 "Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape" XP_034951129.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_034951053.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_034950325.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_034939299.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034944684.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_034943755.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034949182.1 17 Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-69202;Reactome: R-HSA-9616222;Reactome: R-HSA-6804114;Reactome: R-HSA-111448;Reactome: R-HSA-8953750;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-1912408;Reactome: R-HSA-139915;Reactome: R-HSA-113501;Reactome: R-HSA-69656;Reactome: R-HSA-1362277 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin E associated events during G1/S transition";"Transcriptional regulation of granulopoiesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of NOXA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Pre-NOTCH Transcription and Translation";"Activation of PUMA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex" XP_034941026.1 4 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_034938730.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_034939066.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock" XP_034951745.1 9 MetaCyc: PWY-6146;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1 "Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_034945169.1 17 KEGG: 04151+2.7.11.1;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9022692;KEGG: 04926+2.7.11.1;Reactome: R-HSA-68877;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"mTOR signaling pathway";"Human papillomavirus infection";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Regulation of MECP2 expression and activity";"Relaxin signaling pathway";"Mitotic Prometaphase";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_034938848.1 5 KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16 "Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism" XP_034944251.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_034937226.1 5 Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514;MetaCyc: PWY-6855 "Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)" XP_034939238.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_034939574.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_034952534.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_034948974.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_034936435.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034934228.1 11 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167243 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery" XP_034950393.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_034948634.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_034945975.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_034939557.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_034934508.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism" XP_034944280.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_034935108.1 11 MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-6992;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205 "GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose" XP_034945070.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034946715.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_034950459.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_034942759.1 6 Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706 "FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling" XP_034939590.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034951822.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034934369.1 58 Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684 "TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Metalloprotease DUBs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state" XP_034938001.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_034949337.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_034951212.1 15 Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693548 "HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Sensing of DNA Double Strand Breaks" XP_034948298.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_034936197.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_034945202.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034948807.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_034940748.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034950711.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_034950974.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_034941246.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034934098.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_034933882.1 7 MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-7886;MetaCyc: PWY-3385 "Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I" XP_034944638.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034939936.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_034945187.1 6 KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010 "Glycine, serine and threonine metabolism";"Methane metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis";"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)" XP_034939577.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_034937377.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_034937833.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034946043.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_034951374.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_034951304.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_034944009.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_034936157.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034946567.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034937478.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_034940959.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_034949818.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_034949715.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034940326.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_034938729.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_034947520.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_034943245.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_034947645.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034947056.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_034936043.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034938261.1 56 Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764 "Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling" XP_034937505.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034937289.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_034944877.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_034948366.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_034947774.1 4 Reactome: R-HSA-72203;Reactome: R-HSA-4570464;Reactome: R-HSA-72163;Reactome: R-HSA-9610379 "Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway";"HCMV Late Events" XP_034939359.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034943268.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034937518.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955 "Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"RAF activation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_034939921.1 7 KEGG: 00630+2.3.3.9;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7854;MetaCyc: PWY-7118;MetaCyc: PWY-7295;MetaCyc: PWY-6969 "Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"D-xylose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Chitin degradation to ethanol";"L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_034951844.1 8 Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-212300 "Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA" XP_034933683.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_034943277.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034946564.1 14 Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-1474228;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700 "EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Degradation of the extracellular matrix";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_034945998.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034933895.1 25 Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-420092;Reactome: R-HSA-381771;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-392451 "ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G-protein activation";"G alpha (z) signalling events";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma" XP_034950292.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_034947408.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_034943112.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_034942264.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_034949336.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_034952691.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_034952312.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_034934158.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034951233.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-201688 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Synthesis of PC";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL" XP_034942700.1 7 MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695 "Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Purine metabolism";"Neutrophil degranulation" XP_034935897.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034937078.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034933630.1 57 Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8951664 "Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation" XP_034933839.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_034952325.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_034941630.1 11 Reactome: R-HSA-525793;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482 "Myogenesis";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation" XP_034940082.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399 "SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy" XP_034937342.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_034943901.1 32 Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-73776 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape" XP_034948960.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_034946407.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633 "O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_034941197.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034936520.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_034934214.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_034939044.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_034947361.1 17 Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-6804756;Reactome: R-HSA-69601;Reactome: R-HSA-8953750;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-75035 "Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Thermogenesis";"Signaling by SCF-KIT";"Regulation of TP53 Activity through Phosphorylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Transcriptional Regulation by E2F6";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_034940890.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_034945291.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_034939466.1 13 MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism" XP_034944609.1 6 Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_034945976.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_034946946.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_034936151.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034938308.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_034951217.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_034946745.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749 "Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"HCMV Late Events";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs" XP_034949346.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_034941193.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_034948292.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_034942422.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_034948544.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034949624.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034934561.1 12 MetaCyc: PWY-6309;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13 "L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism" XP_034947512.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_034940758.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_034937254.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_034945159.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_034934467.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_034945841.1 13 Reactome: R-HSA-2871809;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;Reactome: R-HSA-2871796;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;KEGG: 04070+3.1.4.11 "FCERI mediated Ca+2 mobilization";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"FCERI mediated MAPK activation";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system" XP_034938517.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034945597.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_034936285.1 12 MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1 "Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Methane metabolism";"Chitin degradation to ethanol";"Pyruvate metabolism";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism" XP_034943463.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_034942635.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_034945269.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling" XP_034939984.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034943084.1 3 MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway" XP_034940517.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_034937379.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_034937761.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034952311.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_034944866.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_034945784.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243 "Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_034949176.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_034943270.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_034947336.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_034936153.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034941233.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_034938431.1 12 KEGG: 00130+1.14.99.60;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-5857 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_034939653.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_034940993.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_034946903.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034937672.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_034949418.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034935306.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034947842.1 19 MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7198;Reactome: R-HSA-380270;MetaCyc: PWY-7220;Reactome: R-HSA-380320;MetaCyc: PWY-7224 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Purine deoxyribonucleosides salvage" XP_034951732.1 3 Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12 "Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism" XP_034937935.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034937178.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034951332.1 3 Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis" XP_034945800.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_034950951.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_034949592.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_034944745.1 16 Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1266695;Reactome: R-HSA-389357;Reactome: R-HSA-416476;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-1433557 "Interleukin receptor SHC signaling";"RET signaling";"Extra-nuclear estrogen signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Interleukin-7 signaling";"CD28 dependent PI3K/Akt signaling";"G alpha (q) signalling events";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Signaling by SCF-KIT" XP_034941199.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034944147.1 4 KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_034942737.1 14 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-165054;Reactome: R-HSA-2173788 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"Rev-mediated nuclear export of HIV RNA";"Downregulation of TGF-beta receptor signaling" XP_034948756.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_034936203.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_034948082.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034937057.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_034945004.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354 "AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy" XP_034949794.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_034942827.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_034946308.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034941555.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231 "Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production" XP_034947725.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_034936279.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_034939505.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_034945894.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_034942963.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948 "Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants" XP_034937758.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_034947081.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_034937206.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034937698.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_034934644.1 20 Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5696400 "Polymerase switching";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Dual Incision in GG-NER" XP_034934673.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034952294.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034941010.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034940116.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_034946468.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Ub-specific processing proteases" XP_034943471.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_034939338.1 10 KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11 "Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis" XP_034952144.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_034946234.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_034951660.1 13 Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928663 "EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse" XP_034937741.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_034935305.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_034949638.1 7 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_034938361.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_034945161.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_034937143.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_034950661.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_034939405.1 4 Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_034950692.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_034951913.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_034937669.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034943334.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034946134.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_034944558.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034948848.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_034938747.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034939133.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Oxidative Stress Induced Senescence" XP_034935422.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression" XP_034945142.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856825 "Neutrophil degranulation";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis" XP_034950179.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_034936374.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034937913.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_034942808.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_034936833.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_034937562.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ion homeostasis";"RAF activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Long-term potentiation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity" XP_034936536.1 24 Reactome: R-HSA-444257;Reactome: R-HSA-354192;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-392451;Reactome: R-HSA-5218921;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-165158;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-9634635;Reactome: R-HSA-5607764 "RSK activation";"Integrin signaling";"mTOR signaling pathway";"Human papillomavirus infection";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"GPVI-mediated activation cascade";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated cell proliferation";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Activation of AKT2";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Relaxin signaling pathway";"RHO GTPases activate PKNs";"Estrogen-stimulated signaling through PRKCZ";"CLEC7A (Dectin-1) signaling" XP_034946032.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)" XP_034938348.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_034952401.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681 "TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling" XP_034942605.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_034940586.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_034947240.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957 "Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_034944233.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_034941835.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_034943474.1 22 MetaCyc: PWY-7619;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-5353;MetaCyc: PWY-7049;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-5080;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+4.2.1.134 "Juniperonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation" XP_034934671.1 3 KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859 "Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade" XP_034940442.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_034935757.1 6 Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis" XP_034946894.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_034946473.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_034947980.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_034946612.1 12 MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4 "Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism" XP_034946599.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_034950083.1 8 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-7817 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis I";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_034942706.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_034935194.1 52 Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-5578749;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-203927;Reactome: R-HSA-73863;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167238 "B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Pausing and recovery of Tat-mediated HIV elongation" XP_034945270.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_034936042.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034947535.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_034944619.1 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560 "Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II" XP_034940953.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_034945255.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_034943756.1 5 Reactome: R-HSA-196843;MetaCyc: PWY-7863;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168 "Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)" XP_034934530.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_034937545.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9609736 "HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors" XP_034950215.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034939237.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_034937533.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_034940590.1 34 Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-3371453 "ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response" XP_034948519.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation" XP_034947799.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_034934377.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034947594.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_034940413.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_034949019.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_034944113.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling" XP_034941156.1 3 MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_034952396.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034948333.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_034933687.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_034934583.1 10 Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-1268020;Reactome: R-HSA-983170;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-381183;Reactome: R-HSA-3371453 "IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"Mitochondrial protein import";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response" XP_034949946.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034951483.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_034939343.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_034944948.1 10 KEGG: 05163+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04070+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153 "Human cytomegalovirus infection";"Inositol phosphate metabolism";"mTOR signaling pathway";"Phosphatidylinositol signaling system";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Human papillomavirus infection" XP_034950294.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_034951596.1 13 Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-445989 "CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_034950303.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_034952372.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_034945697.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_034939824.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789 "TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs" XP_034935714.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_034942202.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034940502.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_034946187.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_034936845.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034935618.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_034952108.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_034939038.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_034947691.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_034943711.1 15 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence" XP_034947054.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism" XP_034937943.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_034952341.1 11 Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801 "Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair" XP_034938515.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_034940676.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_034940425.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_034940097.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_034950846.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_034951079.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_034952473.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034950180.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_034947261.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_034950034.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_034946953.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_034937063.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_034949500.1 16 MetaCyc: PWY-7124;Reactome: R-HSA-70263;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-5484 "Ethylene biosynthesis V (engineered)";"Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Rubisco shunt";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_034950678.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_034946799.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034943156.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_034942027.1 5 MetaCyc: PWY-7159;MetaCyc: PWY-5531;Reactome: R-HSA-189451;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism" XP_034952151.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_034936040.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_034951196.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_034935480.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034940633.1 8 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_034941979.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_034947695.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_034933939.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_034938028.1 20 MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7858 "Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II" XP_034946888.1 27 Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159236 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"HCMV Early Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"HCMV Late Events";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_034937213.1 11 Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_034935644.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_034944747.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_034937475.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_034951178.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_034934859.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034945215.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-450321 "mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_034941877.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_034941125.1 14 MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis" XP_034934433.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_034943192.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_034952283.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_034947204.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation" XP_034948949.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_034946292.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_034936972.1 6 Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5358606 "Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_034936291.1 8 Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-3928665 "Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells" XP_034939605.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_034946111.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725 "Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_034942604.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_034947996.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_034951981.1 8 MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826 "Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Surfactant metabolism" XP_034952632.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_034938465.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034952446.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_034939315.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_034936242.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288 "Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1" XP_034939236.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_034936665.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_034947290.1 17 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_034938518.1 3 Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361 "Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins" XP_034940632.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_034934239.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-1445148 "Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_034942271.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_034947960.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_034949741.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis" XP_034937746.1 56 Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858 "CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity" XP_034938746.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_034952657.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_034950305.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_034951430.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_034936856.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034947768.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_034938818.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_034936848.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_034945363.1 10 Reactome: R-HSA-2197563;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-8941856 "NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling" XP_034941881.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_034942128.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_034950422.1 11 MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;Reactome: R-HSA-8964539 "Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism" XP_034952063.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_034944257.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "PKA activation";"Hedgehog 'off' state";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_034948028.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_034937559.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_034940122.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_034938360.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_034948029.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_034938146.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_034938946.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_034936984.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_034945282.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_034939531.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"