Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_031627303.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_031633078.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_031622387.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins"
XP_031641021.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031626368.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031631149.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_031633331.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031633801.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031639010.1	17	MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5743;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-6679;Reactome: R-HSA-200425;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5789	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis";"Pyruvate metabolism";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Carnitine metabolism";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_031639683.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_031634795.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031640780.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_031629178.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031625478.1	12	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-73772	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape"
XP_031639135.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031623356.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_031616740.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_031619405.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031638278.1	8	Reactome: R-HSA-6791462;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;MetaCyc: PWY-1861;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;MetaCyc: PWY-5723	"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt"
XP_031626420.1	3	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_031631589.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031623945.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031641173.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_031621255.1	4	Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_031639800.1	34	Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-9639288	"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1"
XP_031622375.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_031627033.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031616952.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_031634648.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282	"Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_031640531.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_031624250.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031616690.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031621321.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-5943;MetaCyc: PWY-7939;MetaCyc: PWY-7947;MetaCyc: PWY-6279;MetaCyc: PWY-7591;MetaCyc: PWY-5947;Reactome: R-HSA-1989781;MetaCyc: PWY-7938;KEGG: 00906+2.5.1.32+5.5.1.19	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Beta-carotene biosynthesis";"Chlorobactene biosynthesis";"Flexixanthin biosynthesis";"Myxol-2' fucoside biosynthesis";"Okenone biosynthesis";"Lutein biosynthesis";"PPARA activates gene expression";"Isorenieratene biosynthesis I (actinobacteria)";"Carotenoid biosynthesis"
XP_031622477.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944	"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2"
XP_031624136.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031622377.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_031630317.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031629724.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_031634043.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031622995.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_031620636.1	5	Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Neutrophil degranulation";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_031623204.1	18	KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1	"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism"
XP_031636008.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_031627267.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_031629547.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031621284.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031626620.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031629393.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_031632901.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031627420.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_031623092.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031628526.1	18	Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416	"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_031623215.1	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7177;MetaCyc: PWY-7185	"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I"
XP_031621491.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_031640790.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031640954.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_031627091.1	5	Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation"
XP_031638381.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031627508.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_031626031.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031621492.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_031623550.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031626936.1	6	MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_031617624.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031638826.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-7039	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_031632132.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031623126.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031636521.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031619228.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031623634.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031624517.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031616983.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031620644.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031634715.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031639075.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_031622441.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031626272.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031617857.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_031633561.1	30	Reactome: R-HSA-211163;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-5628897;Reactome: R-HSA-6804758;Reactome: R-HSA-199418;Reactome: R-HSA-8948751;Reactome: R-HSA-6804757;Reactome: R-HSA-198693;Reactome: R-HSA-392451;Reactome: R-HSA-9614399;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-8941332;Reactome: R-HSA-111447;Reactome: R-HSA-389513;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-6804759;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400	"AKT-mediated inactivation of FOXO1A";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Acetylation";"Negative regulation of the PI3K/AKT network";"Regulation of PTEN stability and activity";"Regulation of TP53 Degradation";"AKT phosphorylates targets in the nucleus";"G beta:gamma signalling through PI3Kgamma";"Regulation of localization of FOXO transcription factors";"Thermogenesis";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"RAB GEFs exchange GTP for GDP on RABs";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RUNX2 regulates genes involved in cell migration";"Activation of BAD and translocation to mitochondria";"CTLA4 inhibitory signaling";"mTOR signaling pathway";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Association with Co-factors";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_031632312.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_031630621.1	5	KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661;Reactome: R-HSA-70688	"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Proline catabolism"
XP_031633581.1	7	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine metabolism"
XP_031621108.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_031634154.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031616575.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-349425	"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_031617639.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_031618814.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_031639137.1	34	Reactome: R-HSA-5696395;Reactome: R-HSA-69273;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-69202;Reactome: R-HSA-8939236;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-6782210	"Formation of Incision Complex in GG-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Cyclin D associated events in G1";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"Cyclin E associated events during G1/S transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_031635873.1	18	MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_031616694.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031629816.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_031621580.1	4	MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27	"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_031624242.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031623983.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_031628285.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_031618110.1	16	Reactome: R-HSA-182218;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-190873;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-164939;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-416993	"Nef Mediated CD8 Down-regulation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Gap junction degradation";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"Nef mediated downregulation of CD28 cell surface expression";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors"
XP_031618769.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_031618913.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031627252.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_031640797.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031640971.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031640644.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_031627174.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031618563.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031617339.1	7	Reactome: R-HSA-379716;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;Reactome: R-HSA-6782315	"Cytosolic tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol"
XP_031628916.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031623564.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162	"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_031625834.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_031634741.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031640451.1	14	Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052	"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PC";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis"
XP_031619180.1	8	MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_031630204.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031637514.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_031629308.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031622914.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_031629422.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031628818.1	12	Reactome: R-HSA-8849932;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9609736	"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Purine metabolism";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors"
XP_031626285.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_031636784.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031627678.1	13	MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism"
XP_031633501.1	9	MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8	"Glucosylglycerol biosynthesis";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
XP_031639028.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031639900.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031623174.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031632814.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031618848.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_031625820.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031622102.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031626745.1	9	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_031632390.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031623341.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031617498.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_031639548.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031623191.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_031639643.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031620149.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031639780.1	6	KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52	"Cysteine and methionine metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"Methane metabolism"
XP_031616328.1	6	MetaCyc: PWY-6367;Reactome: R-HSA-1660499;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64+3.1.3.95;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368	"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation"
XP_031623915.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031623970.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_031631757.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031620740.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031618894.1	13	KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7883	"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Anhydromuropeptides recycling II"
XP_031623563.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Transcription of the HIV genome"
XP_031619272.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Rap1 signalling";"Ca2+ pathway";"cGMP effects"
XP_031622259.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031624305.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031618196.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031636993.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-1483166	"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Synthesis of PA"
XP_031626809.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031621457.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_031635875.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031635332.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031630715.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_031625962.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_031634100.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031624659.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_031621535.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031621219.1	4	Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261	"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_031623808.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031638252.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031622161.1	12	Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-166208	"Translation initiation complex formation";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling"
XP_031640426.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_031629531.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031639863.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031638703.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_031634824.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_031630351.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_031621748.1	9	Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-69205	"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription"
XP_031639897.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031637685.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_031641213.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_031640199.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815	"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones"
XP_031624822.1	1	Reactome: R-HSA-419771	"Opsins"
XP_031628478.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031626761.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031617195.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_031621206.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_031628473.1	14	MetaCyc: PWY-5076;MetaCyc: PWY-5108;MetaCyc: PWY-5103;MetaCyc: PWY-5101;MetaCyc: PWY-7767;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5104;Reactome: R-HSA-70895;MetaCyc: PWY-5078;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;KEGG: 00280+2.6.1.42	"L-leucine degradation III";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II";"L-leucine degradation IV (Stickland reaction)";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis IV";"Branched-chain amino acid catabolism";"L-isoleucine degradation II";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine degradation"
XP_031623175.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031628695.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031635702.1	5	MetaCyc: PWY-2201;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20	"Folate transformations I";"Folate transformations II (plants)";"Metabolism of folate and pterines";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes"
XP_031624308.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031621339.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757	"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation"
XP_031625418.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_031624254.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031640635.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031620088.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_031619721.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031622585.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031620288.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_031633498.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_031628626.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031638477.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_031628430.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_031617032.1	5	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_031623922.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_031629321.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031630358.1	4	KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030	"Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis"
XP_031638192.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031632286.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_031618506.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031617597.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6811438	"RAB geranylgeranylation";"Intra-Golgi traffic"
XP_031618707.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031628650.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031624318.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031625803.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-389513	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling"
XP_031626256.1	12	MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-173599;MetaCyc: PWY-3801;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527	"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Stachyose degradation"
XP_031622438.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031617146.1	3	Reactome: R-HSA-975577;Reactome: R-HSA-913709;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"O-linked glycosylation of mucins";"Keratan sulfate biosynthesis"
XP_031618744.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_031630121.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031632309.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_031620889.1	10	KEGG: 00640+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-6537;MetaCyc: PWY-6535;MetaCyc: PWY-6536;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321	"Propanoate metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation V";"beta-Alanine metabolism";"Degradation of GABA";"4-aminobutanoate degradation II";"4-aminobutanoate degradation I";"4-aminobutanoate degradation III";"Butanoate metabolism";"L-glutamate degradation IV"
XP_031638055.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_031618992.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031636757.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2"
XP_031636225.1	13	Reactome: R-HSA-2206308;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4341670;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-1660662	"MPS IV - Morquio syndrome B";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Other glycan degradation";"Defective NEU1 causes sialidosis";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Galactose metabolism";"Glycosphingolipid metabolism"
XP_031626250.1	4	Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17	"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis"
XP_031620697.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031636613.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031628128.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031623758.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_031631685.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_031621991.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402	"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex"
XP_031641251.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031641025.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_031618236.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031635705.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-432040;Reactome: R-HSA-392170;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418217	"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 12";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta"
XP_031637869.1	5	Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_031632336.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031626947.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031626703.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_031634680.1	12	KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4	"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Arachidonic acid metabolism"
XP_031623327.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031632697.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation"
XP_031633534.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_031625273.1	6	MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis"
XP_031623376.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_031634599.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795	"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity"
XP_031626552.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_031635412.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-7285;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_031633893.1	30	Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-2644607;Reactome: R-HSA-1170546;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-68949	"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Orc1 removal from chromatin"
XP_031626413.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_031634121.1	4	Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_031631783.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_031630668.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_031629381.1	17	Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-5357956;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-4086398;Reactome: R-HSA-5689880;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-168638	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Ca2+ pathway";"Ub-specific processing proteases";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway"
XP_031623264.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_031636341.1	11	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane"
XP_031637275.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_031627618.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-6811436	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic"
XP_031626381.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_031640291.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_031638442.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_031623094.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031621000.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_031617336.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031635675.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031628823.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_031629460.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1"
XP_031628614.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism"
XP_031635550.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320	"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation"
XP_031624128.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_031620760.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031627273.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_031623222.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_031631865.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_031626369.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs"
XP_031640722.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031630928.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031622595.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031632989.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7602	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_031639500.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_031640094.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_031639514.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031618449.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031628105.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031630506.1	10	Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_031638336.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_031618804.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_031630160.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031637789.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_031625922.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_031619996.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_031621202.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031622854.1	10	MetaCyc: PWY-4661;MetaCyc: PWY-6362;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;MetaCyc: PWY-6361;MetaCyc: PWY-6372	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_031624488.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_031620967.1	4	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437	"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation"
XP_031621549.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_031630164.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_031640527.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_031630821.1	6	Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8874211	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes"
XP_031639066.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031640986.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_031632197.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031618696.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031622962.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031635619.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031631465.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-5663213	"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs"
XP_031618905.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_031622179.1	12	Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-72702	"Translation initiation complex formation";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition"
XP_031630168.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_031627907.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_031630667.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031640105.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_031623571.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_031634393.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_031625600.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_031638304.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_031633470.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_031622112.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031632205.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_031639330.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031619080.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition"
XP_031622554.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031617415.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459	"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031629660.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_031639411.1	52	Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-6796648;Reactome: R-HSA-73980;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-5250924;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76071;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-73780;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167287	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Chain Elongation";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery"
XP_031640246.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_031620540.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031625513.1	58	Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5689901;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-1234176	"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Metalloprotease DUBs";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_031627058.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031636240.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_031627005.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031624315.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031625937.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism"
XP_031621184.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_031635701.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031621222.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_031631155.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_031625258.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_031638739.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031626732.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_031632372.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031635842.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031627860.1	6	KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165	"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_031632441.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_031632359.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_031624304.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031617190.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031626661.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031624434.1	7	Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_031631785.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031624427.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781	"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression"
XP_031629084.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031627328.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031640204.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_031640205.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_031637884.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4085377	"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins"
XP_031638142.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031618543.1	15	MetaCyc: PWY-7218;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Purine metabolism"
XP_031628835.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_031623111.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031622478.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-9022692	"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity"
XP_031617309.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_031618690.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_031639901.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031635086.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_031620242.1	11	Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_031631940.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031632997.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_031636073.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_031626441.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031623696.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_031621109.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_031623663.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_031622849.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_031633669.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_031618697.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031622025.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_031637336.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_031617065.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_031620978.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_031622883.1	17	Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-174411	"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere"
XP_031621837.1	13	KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-5123;MetaCyc: PWY-7736;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-6859	"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis"
XP_031636837.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_031635072.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031627243.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_031628407.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_031633821.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_031635424.1	18	MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7226	"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_031629039.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-1234176	"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_031619132.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031624930.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_031628683.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_031632599.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization"
XP_031640747.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031619771.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031618997.1	5	Reactome: R-HSA-2173789;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5689603	"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Iron uptake and transport";"UCH proteinases"
XP_031624900.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031627380.1	13	Reactome: R-HSA-8866654;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-8876725;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877;Reactome: R-HSA-5678895;Reactome: R-HSA-110320;Reactome: R-HSA-9646399;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768	"E3 ubiquitin ligases ubiquitinate target proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Protein methylation";"Hedgehog ligand biogenesis";"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis";"Translesion Synthesis by POLH";"Aggrephagy";"Ovarian tumor domain proteases";"HSF1 activation";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_031640739.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031632161.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031618568.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031632341.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534	"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4"
XP_031638919.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031632368.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031622788.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_031626940.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031631014.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031617633.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031631425.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_031641066.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_031637760.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471	"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response"
XP_031634846.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_031629319.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031618729.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031639460.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_031620395.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_031638472.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031632077.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031626869.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_031625630.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031624762.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_031621744.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062	"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis"
XP_031638962.1	24	Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-165158;Reactome: R-HSA-202424;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-444257	"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"FCERI mediated NF-kB activation";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Degradation";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Activation of AKT2";"Downstream TCR signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"RSK activation"
XP_031620043.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_031634806.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_031630350.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_031636245.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_031626699.1	15	Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2"
XP_031625747.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031629181.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_031625782.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_031637219.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031637335.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031626057.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_031637277.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_031635616.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031632171.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_031618118.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031639077.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_031617700.1	13	KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;MetaCyc: PWY-7883	"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II"
XP_031619680.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_031623130.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_031640051.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_031622945.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031627090.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
XP_031629161.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031626361.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031618889.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_031637723.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031625879.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031629668.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031618242.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031636375.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031625903.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090	"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures"
XP_031639226.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031635970.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock"
XP_031629842.1	24	Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-416476	"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events"
XP_031621286.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031622451.1	6	MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;KEGG: 00790+4.2.3.12	"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_031640600.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031633659.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031630873.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031623631.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031630374.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_031623199.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_031637328.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031625686.1	12	KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362	"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenocompound metabolism";"Selenate reduction";"Sulfite oxidation III";"Sulfur metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Transport and synthesis of PAPS"
XP_031640905.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_031632192.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_031617443.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031630490.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_031633361.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_031623316.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_031631891.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031638490.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_031623704.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_031636504.1	4	MetaCyc: PWY-7426;KEGG: 00510+3.2.1.114;MetaCyc: PWY-7920;KEGG: 00513+3.2.1.114	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis"
XP_031622943.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031636952.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031636793.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031625790.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_031625687.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4	"Selenocompound metabolism";"Selenate reduction";"Purine metabolism";"Sulfite oxidation III";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Transport and synthesis of PAPS";"Sulfur metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Purine metabolism"
XP_031640796.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_031629694.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031628899.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031627411.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031628864.1	22	MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7049;MetaCyc: PWY-7606;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-7592;MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-5080;MetaCyc: PWY-7727	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)"
XP_031629815.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_031630381.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031624997.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_031617030.1	5	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_031626168.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_031623871.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_031641142.1	3	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_031621463.1	14	MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-5981	"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III"
XP_031629587.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031623091.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031616396.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031623623.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031622953.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031632869.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_031640485.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031631068.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031627067.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031635037.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031624735.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031631641.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031637738.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031617892.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_031618596.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_031638845.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_031625529.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031625604.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031626488.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031626698.1	15	Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519	"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression"
XP_031640996.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_031636119.1	19	Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828	"VLDL clearance";"LDL clearance";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Chylomicron clearance";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"LDL remodeling";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis"
XP_031624307.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031637583.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031619777.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_031624135.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_031630355.1	4	KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030	"Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis"
XP_031635258.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_031622001.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_031619989.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_031617207.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_031634737.1	5	Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"RAF activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_031617580.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_031627659.1	3	Reactome: R-HSA-194313;Reactome: R-HSA-195399;Reactome: R-HSA-114608	"VEGF ligand-receptor interactions";"VEGF binds to VEGFR leading to receptor dimerization";"Platelet degranulation"
XP_031616890.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_031635741.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_031622084.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-3108214	"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_031622118.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_031632904.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031618942.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031617076.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031633864.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031621725.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031627441.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031637100.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031638220.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031623774.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031620627.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031621306.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_031616471.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031619289.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_031621459.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_031621118.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_031635305.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_031633279.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031633113.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031628697.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031625579.1	20	Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696400	"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Dual Incision in GG-NER"
XP_031620270.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031624316.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031618374.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031635872.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS"
XP_031622560.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_031633614.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144	"Xenobiotics";"Phase I - Functionalization of compounds";"Endogenous sterols";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling"
XP_031621445.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_031619254.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700	"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_031640904.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_031619574.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_031616421.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031627619.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation"
XP_031620662.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031640756.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_031621716.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031629385.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031625521.1	8	MetaCyc: PWY-7193;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7181;Reactome: R-HSA-73614;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5	"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes"
XP_031622366.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_031619397.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031634551.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031628897.1	6	KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7395	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_031630356.1	4	KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931	"Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis"
XP_031640022.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4085377	"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of SUMOylation proteins"
XP_031624877.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_031635415.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031616803.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031620405.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_031633767.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031620594.1	10	MetaCyc: PWY-7849;Reactome: R-HSA-975634;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453864;Reactome: R-HSA-977225	"Urate conversion to allantoin III";"Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Retinoid cycle disease events";"Amyloid fiber formation"
XP_031638819.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_031633016.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031638253.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031632444.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_031630228.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_031640099.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822	"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_031618200.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031629205.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_031636911.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031624131.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_031633520.1	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_031640598.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_031632214.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031630353.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_031628696.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031627350.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031635806.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031630999.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_031629368.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031622791.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_031638007.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_031623670.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031626984.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_031626977.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_031623096.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031618422.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031626985.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031629693.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031622253.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031632009.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_031640330.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_031629107.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_031622048.1	5	Reactome: R-HSA-3656237;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928	"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis"
XP_031624417.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031623328.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031637444.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031630559.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031626038.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031632484.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_031622255.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031641196.1	83	Reactome: R-HSA-2219530;Reactome: R-HSA-5654689;Reactome: R-HSA-9634285;Reactome: R-HSA-912526;Reactome: R-HSA-8865999;Reactome: R-HSA-5637810;Reactome: R-HSA-1250347;Reactome: R-HSA-5654695;Reactome: R-HSA-9645135;Reactome: R-HSA-5654704;Reactome: R-HSA-9028335;Reactome: R-HSA-112412;Reactome: R-HSA-8851805;Reactome: R-HSA-74751;Reactome: R-HSA-6807004;Reactome: R-HSA-5663213;Reactome: R-HSA-186763;Reactome: R-HSA-5655253;Reactome: R-HSA-9027284;Reactome: R-HSA-9664565;Reactome: R-HSA-8853338;Reactome: R-HSA-5654688;Reactome: R-HSA-1963640;Reactome: R-HSA-179812;Reactome: R-HSA-74749;Reactome: R-HSA-9607240;Reactome: R-HSA-1433559;Reactome: R-HSA-8983432;Reactome: R-HSA-9026519;Reactome: R-HSA-2871809;Reactome: R-HSA-354194;Reactome: R-HSA-1295596;Reactome: R-HSA-8856828;Reactome: R-HSA-167044;Reactome: R-HSA-5654732;Reactome: R-HSA-983695;Reactome: R-HSA-2179392;Reactome: R-HSA-2871796;Reactome: R-HSA-2428933;Reactome: R-HSA-8851907;Reactome: R-HSA-5655302;Reactome: R-HSA-1257604;Reactome: R-HSA-8856825;Reactome: R-HSA-5654706;Reactome: R-HSA-109704;Reactome: R-HSA-512988;Reactome: R-HSA-5654710;Reactome: R-HSA-180336;Reactome: R-HSA-9034864;Reactome: R-HSA-5654726;Reactome: R-HSA-375165;Reactome: R-HSA-1839117;Reactome: R-HSA-1250196;Reactome: R-HSA-5654720;Reactome: R-HSA-8875360;Reactome: R-HSA-5654712;Reactome: R-HSA-8853659;Reactome: R-HSA-391160;Reactome: R-HSA-389359;Reactome: R-HSA-8875555;Reactome: R-HSA-5654700;Reactome: R-HSA-2424491;Reactome: R-HSA-9028731;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-5654727;Reactome: R-HSA-5654733;Reactome: R-HSA-1963642;Reactome: R-HSA-8853334;Reactome: R-HSA-8875656;Reactome: R-HSA-5654693;Reactome: R-HSA-210993;Reactome: R-HSA-388841;Reactome: R-HSA-5673001;Reactome: R-HSA-1236382;Reactome: R-HSA-6811558;Reactome: R-HSA-5654699;Reactome: R-HSA-180292;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-5655291;Reactome: R-HSA-2730905;Reactome: R-HSA-5654719	"Constitutive Signaling by Aberrant PI3K in Cancer";"PI-3K cascade:FGFR1";"Constitutive Signaling by Overexpressed ERBB2";"Interleukin receptor SHC signaling";"MET activates PTPN11";"Constitutive Signaling by EGFRvIII";"SHC1 events in ERBB4 signaling";"PI-3K cascade:FGFR2";"STAT5 Activation";"SHC-mediated cascade:FGFR3";"Activated NTRK2 signals through PI3K";"SOS-mediated signalling";"MET activates RAS signaling";"Insulin receptor signalling cascade";"Negative regulation of MET activity";"RHO GTPases Activate WASPs and WAVEs";"Downstream signal transduction";"Signaling by FGFR2 in disease";"Erythropoietin activates RAS";"Signaling by ERBB2 KD Mutants";"Signaling by FGFR3 point mutants in cancer";"SHC-mediated cascade:FGFR1";"GRB2 events in ERBB2 signaling";"GRB2 events in EGFR signaling";"Signal attenuation";"FLT3 Signaling";"Regulation of KIT signaling";"Interleukin-15 signaling";"Activated NTRK2 signals through RAS";"FCERI mediated Ca+2 mobilization";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Spry regulation of FGF signaling";"Clathrin-mediated endocytosis";"Signalling to RAS";"Negative regulation of FGFR3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"EGFR Transactivation by Gastrin";"FCERI mediated MAPK activation";"SHC-related events triggered by IGF1R";"MET activates PI3K/AKT signaling";"Signaling by FGFR1 in disease";"PIP3 activates AKT signaling";"Cargo recognition for clathrin-mediated endocytosis";"FRS-mediated FGFR3 signaling";"PI3K Cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI-3K cascade:FGFR3";"SHC1 events in EGFR signaling";"Activated NTRK3 signals through RAS";"Negative regulation of FGFR1 signaling";"NCAM signaling for neurite out-growth";"Signaling by cytosolic FGFR1 fusion mutants";"SHC1 events in ERBB2 signaling";"PI-3K cascade:FGFR4";"InlB-mediated entry of Listeria monocytogenes into host cell";"FRS-mediated FGFR4 signaling";"RET signaling";"Signal regulatory protein family interactions";"CD28 dependent Vav1 pathway";"MET activates RAP1 and RAC1";"FRS-mediated FGFR2 signaling";"DAP12 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR4 signaling";"PI3K events in ERBB2 signaling";"Signaling by FGFR3 fusions in cancer";"MET receptor recycling";"FRS-mediated FGFR1 signaling";"Tie2 Signaling";"Costimulation by the CD28 family";"RAF/MAP kinase cascade";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC-mediated cascade:FGFR2";"GAB1 signalosome";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by FGFR4 in disease";"Role of LAT2/NTAL/LAB on calcium mobilization";"SHC-mediated cascade:FGFR4"
XP_031619564.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031640062.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_031640534.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919	"Degradation of the extracellular matrix";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils"
XP_031629318.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031635054.1	12	MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I"
XP_031638682.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_031639627.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_031630265.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031623850.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_031636414.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_031638954.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_031639160.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031622744.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_031621951.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031635912.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_031637493.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_031634072.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_031621588.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_031640002.1	6	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-389661	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Glyoxylate metabolism and glycine degradation"
XP_031641045.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_031627531.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031622215.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031625388.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_031637688.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_031638275.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_031636103.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_031620173.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_031631583.1	13	MetaCyc: PWY-5133;MetaCyc: PWY-7857;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108	"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Cis-genanyl-coa degradation";"Propanoate metabolism";"Methane metabolism";"Lupulone and humulone biosynthesis";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Ethanol oxidation";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V"
XP_031630823.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8874211	"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes"
XP_031616410.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031637423.1	13	MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5	"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Methylaspartate cycle";"Citrate cycle (TCA cycle)"
XP_031633537.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_031633728.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_031628807.1	5	KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_031637711.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031627421.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_031620858.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_031640287.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_031632194.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_031632755.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_031617161.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_031619030.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031634555.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031635094.1	31	Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-6519;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-4381;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-6799;MetaCyc: PWY-6282;MetaCyc: PWY-7723;MetaCyc: PWY-5971;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-6113;MetaCyc: PWY-5994;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663	"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bacterial bioluminescence";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)"
XP_031624022.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_031632875.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_031629328.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_031624493.1	5	MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855	"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)"
XP_031621515.1	5	MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation"
XP_031634694.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN"
XP_031633758.1	19	Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480	"Scavenging by Class F Receptors";"Chylomicron clearance";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"VLDL clearance";"Scavenging by Class B Receptors";"LDL clearance";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"VLDL assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors"
XP_031623230.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031625804.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337	"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding"
XP_031626910.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795	"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity"
XP_031625393.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_031631384.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031640568.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_031627914.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_031631081.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031617352.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_031626019.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031631543.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031628906.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031624756.1	6	Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-201722	"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Formation of the beta-catenin:TCF transactivating complex"
XP_031627456.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_031626562.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031635076.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031619704.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_031626554.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_031620021.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_031628027.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031630520.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031635546.1	5	Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14	"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation"
XP_031629183.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_031640108.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_031626033.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031622049.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_031635179.1	15	Reactome: R-HSA-9665233;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9665250;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-9665251;Reactome: R-HSA-9665245;Reactome: R-HSA-9652282;Reactome: R-HSA-5637810;Reactome: R-HSA-9665246;Reactome: R-HSA-9665249	"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to afatinib"
XP_031641099.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031635099.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031618855.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation"
XP_031627333.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031633854.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736	"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors"
XP_031625780.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_031638684.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031622937.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031625059.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_031622342.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105	"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport"
XP_031623629.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_031640570.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_031640932.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031631302.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031634992.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031632412.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031630551.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_031620484.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031639945.1	4	Reactome: R-HSA-189483;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874	"Heme degradation";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation I"
XP_031633165.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7602	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_031627854.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_031631194.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031639515.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-7559	"Glutathione metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway"
XP_031636466.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_031635798.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031622449.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_031621106.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_031621952.1	16	Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569	"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_031616698.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031629037.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex"
XP_031635832.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031630665.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031630384.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031623363.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031622923.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031620508.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_031621342.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-5578749	"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs"
XP_031625608.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031630294.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"T cell receptor signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_031628837.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-983168;Reactome: R-HSA-3065676	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)"
XP_031635196.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_031624516.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031617246.1	5	KEGG: 00520+1.3.1.98;MetaCyc: PWY-7953;MetaCyc: PWY-6387;MetaCyc: PWY-6386;KEGG: 00550+1.3.1.98	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"Peptidoglycan biosynthesis"
XP_031629185.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_031630786.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031622916.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031621546.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_031622267.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_031631174.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031619962.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_031620329.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031631787.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031630064.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_031617290.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031618926.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031628532.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_031630416.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-442720	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_031635203.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031625543.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_031634293.1	7	Reactome: R-HSA-71336;MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6	"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_031624317.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031638210.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031622401.1	12	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"G alpha (q) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031640202.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_031630032.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031625720.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_031619702.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_031634452.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_031626418.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_031627848.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031621382.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031625057.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_031623627.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_031630828.1	11	Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096	"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"HS-GAG degradation"
XP_031624309.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031621440.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_031617052.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459	"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031631756.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031628850.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031635655.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation"
XP_031639801.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_031617448.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_031625363.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint"
XP_031616591.1	9	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"tRNA modification in the nucleus and cytosol"
XP_031623299.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_031620147.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031632696.1	4	MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59	"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_031617503.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642	"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_031633460.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_031622033.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_031636212.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031628346.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031640934.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031626273.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031625125.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_031632369.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031628904.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031627924.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II"
XP_031628702.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031626998.1	4	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823;MetaCyc: PWY-7887	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_031636916.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031640809.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633	"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_031633530.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_031627617.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic"
XP_031634578.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_031625599.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_031618208.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031617745.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_031617769.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_031639105.1	7	KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;Reactome: R-HSA-1474151;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"Folate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Folate transformations II (plants)"
XP_031641043.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_031619274.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_031624742.1	16	Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-75955	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation"
XP_031618117.1	26	Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736	"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Post-chaperonin tubulin folding pathway";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors"
XP_031640422.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6802948	"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants"
XP_031624600.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_031640289.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_031628081.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-5674400	"Macroautophagy";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_031626175.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-77588	"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_031638343.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031621207.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_031627116.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_031634058.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031627102.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer"
XP_031640066.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166	"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_031640708.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031632316.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031622407.1	12	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"PI3K-Akt signaling pathway";"G alpha (q) signalling events";"mTOR signaling pathway"
XP_031618441.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821	"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification"
XP_031623006.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031631605.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_031622340.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_031625805.1	22	Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins"
XP_031621141.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_031619699.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031640860.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031619365.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_031626449.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_031626803.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_031629764.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031618732.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031636647.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031617979.1	7	MetaCyc: PWY-7807;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610;MetaCyc: PWY-6605;Reactome: R-HSA-6798695;MetaCyc: PWY-7805	"Glyphosate degradation III";"Purine salvage";"Purine metabolism";"Adenine salvage";"Adenine and adenosine salvage II";"Neutrophil degranulation";"(aminomethyl)phosphonate degradation"
XP_031640716.1	9	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_031626991.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-180910	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs"
XP_031624367.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031625795.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_031619806.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_031622392.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6794361;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins";"Neutrophil degranulation"
XP_031616892.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_031641082.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031628617.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_031618544.1	6	KEGG: 00680+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347	"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis"
XP_031640293.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_031635083.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_031618073.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031630822.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_031637395.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_031619299.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_031635661.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_031619065.1	8	MetaCyc: PWY-7193;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-6556	"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II"
XP_031629517.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841	"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines"
XP_031630880.1	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
XP_031622564.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_031621695.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_031636992.1	33	Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-8939236;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-69273;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-674695	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Cyclin D associated events in G1";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events"
XP_031616842.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031617108.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_031624206.1	6	Reactome: R-HSA-74259;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-6608	"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III"
XP_031631172.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_031639910.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine metabolism";"Neutrophil degranulation";"Purine salvage";"Surfactant metabolism"
XP_031620542.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-1368082	"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Estrogen-dependent gene expression";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Generic Transcription Pathway";"RORA activates gene expression"
XP_031631150.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_031623117.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031620808.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031622948.1	14	Reactome: R-HSA-399997;Reactome: R-HSA-500657;Reactome: R-HSA-418217;MetaCyc: PWY-8052;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-4086398;Reactome: R-HSA-434316;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11	"Acetylcholine regulates insulin secretion";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Ca2+ pathway";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_031639787.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031619540.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031641249.1	15	Reactome: R-HSA-176034;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167238	"Interactions of Tat with host cellular proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_031640938.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_031622257.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031626411.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756	"Regulation of PTEN stability and activity";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation"
XP_031623119.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031631660.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_031621902.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031618624.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031620485.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031619523.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031621642.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031623614.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031640930.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031636920.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031640109.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_031617068.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031638182.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031640085.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_031616908.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_031624505.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_031622087.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_031630163.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_031620441.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_031638491.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031619660.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_031635647.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922	"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis"
XP_031630177.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_031617753.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031626611.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031629092.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5578775	"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Ion homeostasis"
XP_031638423.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031632535.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_031640951.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031622532.1	7	MetaCyc: PWY-7836;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-5129;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis"
XP_031625275.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_031632181.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_031617020.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_031626632.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_031637435.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_031639948.1	10	Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-9022702	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands"
XP_031634254.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_031634633.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031620505.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
XP_031639978.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031619290.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_031624567.1	3	Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144	"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_031631066.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031617353.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031619709.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031634302.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_031621343.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031630419.1	4	KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;MetaCyc: PWY-8026;Reactome: R-HSA-6807062	"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol"
XP_031641062.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_031638421.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031620842.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_031636716.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031631013.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031626677.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_031628699.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_031621760.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031631726.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_031640839.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031629582.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_031640906.1	17	Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-9616222;Reactome: R-HSA-111448;Reactome: R-HSA-69656;Reactome: R-HSA-2559585;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408	"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Transcriptional regulation of granulopoiesis";"Activation of NOXA and translocation to mitochondria";"Cyclin A:Cdk2-associated events at S phase entry";"Oncogene Induced Senescence";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation"
XP_031632576.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031641143.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031628792.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031621562.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031618902.1	7	Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-212300	"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"HCMV Early Events";"PRC2 methylates histones and DNA"
XP_031630029.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_031637972.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031629230.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031618557.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031633013.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_031630601.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031638584.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031623907.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031640841.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031638478.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_031630820.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031638460.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_031627506.1	26	Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736	"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Aggrephagy";"HCMV Early Events";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors"
XP_031640889.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_031624506.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031617952.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_031625035.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031621170.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_031625609.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_031635766.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_031622963.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_031633383.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_031626634.1	5	MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527	"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Stachyose degradation"
XP_031627954.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_031640821.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001	"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_031627382.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_031632195.1	4	KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III"
XP_031627738.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031621950.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692	"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity"
XP_031622961.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031629124.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_031631270.1	12	MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;MetaCyc: PWY-7901;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6309;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-2821	"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine"
XP_031636601.1	15	Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580	"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence"
XP_031633107.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031617910.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031635065.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_031617078.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031632892.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031632928.1	7	Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22	"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_031628205.1	6	KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-622	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis"
XP_031641071.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_031638563.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72187	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing"
XP_031617977.1	7	MetaCyc: PWY-7805;Reactome: R-HSA-6798695;MetaCyc: PWY-6610;MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Neutrophil degranulation";"Adenine salvage";"Adenine and adenosine salvage II";"Purine metabolism";"Purine salvage";"Glyphosate degradation III"
XP_031623749.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031639249.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031617644.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031626615.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_031617232.1	10	MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-7909	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)"
XP_031638825.1	7	MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351	"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_031640028.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031622661.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events"
XP_031638828.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204	"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
XP_031638653.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031622946.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031633507.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_031638402.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031628826.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_031624436.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_031632334.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031640911.1	11	MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7821;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-5695;MetaCyc: PWY-6607;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5	"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_031616861.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031639820.1	7	KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_031634385.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031637759.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031622704.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_031624938.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_031620372.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation"
XP_031623865.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_031624661.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031625858.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031630598.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031618599.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_031631686.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_031617058.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_031618393.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031640740.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031619990.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_031636762.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031639703.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031638778.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031640566.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_031631075.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031630457.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_031617595.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_031616400.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031625731.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031618914.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_031632570.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841	"Regulation of PTEN gene transcription";"HCMV Early Events";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines"
XP_031632223.1	11	Reactome: R-HSA-111459;Reactome: R-HSA-194840;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-111464	"Activation of caspases through apoptosome-mediated cleavage";"Rho GTPase cycle";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_031619918.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031624150.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_031633726.1	3	Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_031631754.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_031633050.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_031625326.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031617258.1	5	Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704	"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade"
XP_031633133.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031619814.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape"
XP_031641202.1	10	Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-7344	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism";"Galactose catabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis"
XP_031636774.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031619527.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_031618336.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031621243.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031640476.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031616552.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_031619992.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Peptide chain elongation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_031628919.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031618207.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031638838.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_031623481.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_031636726.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_031622654.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_031628917.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031629896.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750	"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6"
XP_031618644.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031630047.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031621187.1	5	KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536	"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_031632917.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031640070.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_031625830.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_031618945.1	7	KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7838;MetaCyc: PWY-7836	"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis"
XP_031638290.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_031618116.1	17	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Fanconi Anemia Pathway";"Human cytomegalovirus infection";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_031631676.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031633522.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_031624902.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_031633911.1	6	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-389661;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Glyoxylate metabolism and glycine degradation";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_031634289.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031630314.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031639002.1	17	MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5743;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-196780;MetaCyc: PWY-6679	"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"3-hydroxypropanoate cycle";"Pyruvate metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Carnitine metabolism";"Biotin transport and metabolism";"Jadomycin biosynthesis"
XP_031627032.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031622737.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031634536.1	10	MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1	"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism"
XP_031619677.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031633823.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_031638245.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031622561.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_031620286.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_031616697.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031630491.1	13	MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-7736;MetaCyc: PWY-5123	"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_031622514.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_031640481.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031630417.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-164378	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation in glucagon signalling"
XP_031626503.1	5	MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_031624871.1	6	MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1	"Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism"
XP_031623147.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031634860.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_031624149.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_031633402.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031623900.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031621474.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031620909.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_031617167.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_031625396.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031637765.1	13	MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5030;KEGG: 00670+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841	"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate transformations II (plants)"
XP_031630997.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031618074.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031626850.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440	"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_031621809.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031640750.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_031627769.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_031623274.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_031637783.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_031635220.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_031635413.1	6	MetaCyc: PWY-7286;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;Reactome: R-HSA-6787450	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion"
XP_031626440.1	27	Reactome: R-HSA-111367;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-9010553;Reactome: R-HSA-159227;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-72086;Reactome: R-HSA-72187;Reactome: R-HSA-77588;Reactome: R-HSA-159236;Reactome: R-HSA-77595;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-113418;Reactome: R-HSA-73856;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-159230;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-159231	"SLBP independent Processing of Histone Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"Regulation of expression of SLITs and ROBOs";"Transport of the SLBP independent Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"mRNA Capping";"mRNA 3'-end processing";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Processing of Intronless Pre-mRNAs";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP Dependant Mature mRNA";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_031636006.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_031628145.1	14	MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-2201;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1	"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Photorespiration ";"Glycine betaine degradation I";"Folate transformations I";"Folate polyglutamylation";"Metabolism of folate and pterines";"One carbon pool by folate";"Glycine betaine degradation II (mammalian)";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism"
XP_031627661.1	3	Reactome: R-HSA-114608;Reactome: R-HSA-194313;Reactome: R-HSA-195399	"Platelet degranulation";"VEGF ligand-receptor interactions";"VEGF binds to VEGFR leading to receptor dimerization"
XP_031619361.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_031632318.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_031628816.1	12	Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-451308	"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor"
XP_031621963.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_031622469.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_031635411.1	6	MetaCyc: PWY-7285;Reactome: R-HSA-6787450;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;Reactome: R-HSA-8868766	"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"rRNA processing in the mitochondrion"
XP_031623522.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031632905.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031625988.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031640505.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_031635703.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031627724.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031640329.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61	"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_031640483.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031638090.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031636004.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_031617945.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_031616914.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_031619963.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_031632139.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031624629.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031629873.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031624734.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_031627437.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase"
XP_031624518.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_031623322.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031625778.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_031628429.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031635603.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031641040.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031621722.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_031627942.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_031633332.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_031622413.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031617113.1	5	KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168	"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_031627256.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_031626492.1	5	MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7185	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine metabolism";"Neutrophil degranulation";"UTP and CTP dephosphorylation I"
XP_031634924.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031620824.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_031637331.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031632583.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031628531.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_031621412.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_031619070.1	8	MetaCyc: PWY-7181;Reactome: R-HSA-73614;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7193	"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I"
XP_031618230.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031627819.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031621292.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031635928.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031627236.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_031636610.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031637596.1	1	Reactome: R-HSA-6803529	"FGFR2 alternative splicing"
XP_031635112.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_031630173.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_031616329.1	6	MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;MetaCyc: PWY-6367	"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism"
XP_031635238.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031634646.1	6	KEGG: 00300+4.3.3.7;KEGG: 00261+4.3.3.7;MetaCyc: PWY-2942;MetaCyc: PWY-8088;MetaCyc: PWY-2941;MetaCyc: PWY-5097	"Lysine biosynthesis";"Monobactam biosynthesis";"L-lysine biosynthesis III";"Dipicolinate biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis VI"
XP_031632243.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031631435.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_031619400.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031619542.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_031630557.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031621413.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_031632902.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031623831.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031618967.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031626452.1	8	Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880	"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases"
XP_031618540.1	15	KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40	"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Purine metabolism"
XP_031625325.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031627564.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_031617394.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_031635126.1	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781	"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis"
XP_031629040.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_031620085.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits"
XP_031622608.1	2	KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26	"Starch and sucrose metabolism";"Galactose metabolism"
XP_031634434.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_031631709.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031633354.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031632272.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_031628739.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031618154.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_031632116.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state"
XP_031640392.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053	"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II"
XP_031631393.1	6	MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22	"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions"
XP_031620065.1	57	Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-532668;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-1234176	"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_031628649.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031640433.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_031633555.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031624574.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_031635610.1	12	MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II"
XP_031628097.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795	"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity"
XP_031631390.1	8	KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism"
XP_031627923.1	10	MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112	"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification"
XP_031631148.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_031633188.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_031627066.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031626755.1	4	MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism"
XP_031621945.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_031619851.1	33	Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-69656;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-69273;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-8939236;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-69202;Reactome: R-HSA-6781827	"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Cyclin D associated events in G1";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"Cyclin E associated events during G1/S transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_031625283.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_031631880.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031618947.1	7	MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662	"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_031628038.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031629682.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_031628039.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516	"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane"
XP_031635852.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_031623713.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_031623517.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031632993.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_031623352.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_031618595.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_031628812.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_031620371.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_031621609.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031619816.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776	"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_031640201.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_031618144.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031635700.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031641184.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_031635858.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031628738.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031632274.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_031625500.1	3	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_031632310.1	13	MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism"
XP_031631036.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_031620634.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031629772.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031630035.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031636661.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_031619142.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-1169091	"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells"
XP_031629194.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_031630571.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031635127.1	4	Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;MetaCyc: PWY-2781	"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis"
XP_031626614.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031625382.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_031621954.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation"
XP_031639958.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_031630442.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_031630746.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_031622146.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031636741.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031625023.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_031623427.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_031639751.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_031639798.1	34	Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-159236	"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031631289.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_031629263.1	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_031636908.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031616411.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031621197.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031622119.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_031639680.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_031632053.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031617056.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_031620640.1	5	MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Vitamin B6 metabolism"
XP_031635087.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031617121.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031630794.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_031631706.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031633211.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_031639583.1	5	MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_031637106.1	5	Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661	"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_031622760.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_031633242.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_031636218.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_031624386.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation"
XP_031632687.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_031628963.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_031626779.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031624190.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031639540.1	6	Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166;MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668	"Synthesis of PG";"Glycerophospholipid metabolism";"Synthesis of PA";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I"
XP_031636765.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031625383.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_031627810.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_031628373.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031640015.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_031632704.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_031635591.1	7	KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-5683826	"Purine metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Surfactant metabolism"
XP_031623661.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604	"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling"
XP_031626762.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031632839.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_031632107.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-182218	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation"
XP_031633182.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_031628856.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_031617657.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553	"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs"
XP_031628505.1	14	Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167242	"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_031624178.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_031637297.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031633120.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031622047.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2"
XP_031632135.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031640957.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_031640879.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_031619129.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_031616971.1	5	KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_031631464.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs"
XP_031622245.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031636771.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031630316.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031632532.1	4	MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8	"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_031627587.1	24	KEGG: 04150+2.7.11.11;Reactome: R-HSA-432040;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5621575;Reactome: R-HSA-111931;Reactome: R-HSA-4420097;Reactome: R-HSA-5610783;Reactome: R-HSA-8963896;Reactome: R-HSA-163615;Reactome: R-HSA-9010642;Reactome: R-HSA-392517;Reactome: R-HSA-381676;Reactome: R-HSA-9634600;Reactome: R-HSA-442720;Reactome: R-HSA-163560;Reactome: R-HSA-5687128;Reactome: R-HSA-422356;Reactome: R-HSA-163358;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-8853659;Reactome: R-HSA-180024	"mTOR signaling pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of CREB";"VEGFA-VEGFR2 Pathway";"Degradation of GLI2 by the proteasome";"HDL assembly";"PKA activation";"ROBO receptors bind AKAP5";"Rap1 signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Triglyceride catabolism";"MAPK6/MAPK4 signaling";"Regulation of insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"RET signaling";"DARPP-32 events"
XP_031630773.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
XP_031638956.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_031640023.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031621694.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031629019.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_031621013.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_031640012.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031618238.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031621140.1	19	Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480	"Scavenging by Class F Receptors";"Chylomicron clearance";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"VLDL clearance";"Scavenging by Class B Receptors";"LDL clearance";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors"
XP_031631602.1	13	Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52	"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation"
XP_031617194.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_031634617.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031639594.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031630589.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_031619648.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_031626129.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031634104.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_031631421.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031627927.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031639140.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_031634861.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_031634197.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031618301.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_031616814.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031633476.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_031623450.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031637988.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031626371.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031632429.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440	"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_031619701.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031637592.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031621091.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_031620513.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_031621083.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_031635592.1	14	Reactome: R-HSA-5693579;MetaCyc: PWY-7511;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5689603;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Homologous DNA Pairing and Strand Exchange";"Protein ubiquitination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"UCH proteinases";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_031624248.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031628067.1	9	MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-6983;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442	"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_031619326.1	29	Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823	"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_031626094.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031620958.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_031632324.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_031632919.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031626326.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031638727.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031623362.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031624352.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031617272.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031619445.1	6	Reactome: R-HSA-6785470;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion"
XP_031618958.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031637286.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_031621964.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257	"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Neddylation";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Degradation of AXIN"
XP_031619935.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_031623384.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_031630156.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031638104.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031618486.1	5	Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-75105	"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis"
XP_031629571.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031628914.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031638447.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_031640508.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_031631730.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031641217.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031633111.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)"
XP_031629367.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031631703.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031625422.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_031626399.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031621168.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031621759.1	8	MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
XP_031627723.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_031640363.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_031632131.1	3	KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691	"Purine metabolism";"Caffeine metabolism";"Urate conversion to allantoin I"
XP_031628804.1	26	Reactome: R-HSA-3371568;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657	"Attenuation phase";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes"
XP_031638702.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_031634910.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031626480.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031629550.1	20	KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-735;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7338	"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_031627063.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031622548.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031620396.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_031632263.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031621126.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031619014.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031623559.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_031630251.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_031638289.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031631002.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031636494.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031617894.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031637563.1	17	Reactome: R-HSA-74259;MetaCyc: PWY-4202;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-6644	"Purine catabolism";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis"
XP_031629722.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_031623714.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_031621812.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_031621274.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_031616407.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031626834.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031618053.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_031618219.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031623010.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031623302.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_031623423.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_031630380.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031629588.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031632853.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_031640736.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031626459.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031631596.1	13	MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52	"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_031632144.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031632688.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031636919.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031618187.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031626857.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852	"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy"
XP_031636756.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)"
XP_031634719.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031628779.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_031637535.1	3	MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695	"Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation"
XP_031624875.1	3	KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
XP_031618166.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_031625668.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695	"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation"
XP_031631462.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation"
XP_031618740.1	17	Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER"
XP_031631795.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_031622032.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031618197.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031619887.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031628786.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031631712.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031620375.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031622345.1	18	Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167243	"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_031627597.1	15	Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700	"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_031638483.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031621640.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_031633258.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031632256.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031632344.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_031637174.1	30	Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-2644607;Reactome: R-HSA-5607761;Reactome: R-HSA-1170546;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-2644606;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-69231	"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Prolactin receptor signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"Neddylation";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1"
XP_031624430.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_031630415.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation"
XP_031622394.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031617544.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031627089.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108	"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_031630995.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031636742.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031616438.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_031623200.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_031635200.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031617902.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_031628236.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031626600.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_031617623.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031640333.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_031622810.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_031627559.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6807505;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination"
XP_031623459.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031623653.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_031641063.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_031617771.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031628693.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031633143.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_031621480.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_031619944.1	3	Reactome: R-HSA-203927;Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"MicroRNA (miRNA) biogenesis";"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_031636335.1	18	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_031637363.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_031618239.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031630033.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031626224.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_031622039.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989	"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_031621257.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031638474.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_031626939.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031622384.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031620856.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_031622437.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031638386.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_031633490.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031623919.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031636314.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_031636371.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031637330.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031622404.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031636171.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031625238.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_031618668.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_031635750.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_031641214.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_031634748.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_031640891.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_031621410.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_031618645.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031629980.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031636096.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_031624581.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_031616326.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_031618965.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_031629638.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031636560.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_031627857.1	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism";"Entner-Doudoroff pathway I"
XP_031624361.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031638572.1	3	KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_031635012.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031640931.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_031617941.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_031636014.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_031640535.1	10	Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"Negative regulation of MET activity";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_031625585.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031622218.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031620787.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031623955.1	3	Reactome: R-HSA-5635838;Reactome: R-HSA-525793;Reactome: R-HSA-5632681	"Activation of SMO";"Myogenesis";"Ligand-receptor interactions"
XP_031626425.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen chain trimerization"
XP_031621838.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events"
XP_031633777.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_031635645.1	4	KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_031636318.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_031625394.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes"
XP_031622529.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_031634576.1	3	MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_031627806.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031627813.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_031619359.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_031635652.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_031640935.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031626260.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031616930.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031620825.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_031617002.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031616428.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031634940.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031637421.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6969	"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_031626738.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_031621505.1	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_031633144.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_031628676.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031639213.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765	"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression"
XP_031623259.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031627284.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031618382.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031617479.1	14	Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_031636320.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031622256.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031619878.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031635649.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_031637852.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031618060.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031640328.1	14	MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-4302;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-3781	"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)"
XP_031629330.1	6	Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import"
XP_031621181.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_031630532.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_031619646.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_031625620.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_031629206.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-6798695	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Neutrophil degranulation"
XP_031637786.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031620956.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031616799.1	14	MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_031631591.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-912446	"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination"
XP_031628964.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_031628645.1	6	KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165	"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_031626487.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_031629976.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031635874.1	18	MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)"
XP_031638224.1	29	Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-3108214;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938	"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"SUMOylation of DNA damage response and repair proteins";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)"
XP_031621536.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031622090.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210	"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_031636396.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_031634647.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632	"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_031632798.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031632522.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031639879.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_031619877.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031635773.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031638399.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_031637409.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031618347.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_031632255.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031627797.1	6	MetaCyc: PWY-5941;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731	"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III"
XP_031635004.1	15	Reactome: R-HSA-1236382;Reactome: R-HSA-9665245;Reactome: R-HSA-9634285;Reactome: R-HSA-9665251;Reactome: R-HSA-9652282;Reactome: R-HSA-5637810;Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-9665247;Reactome: R-HSA-9665233;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9665250	"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to AEE788"
XP_031630375.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_031633504.1	3	KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate"
XP_031617043.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_031626052.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_031627553.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_031639513.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031621395.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_031635828.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_031635001.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_031618779.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031622658.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031625282.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_031617888.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_031617062.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_031627745.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031635679.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_031624464.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031634179.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031617199.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031623625.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_031629625.1	13	MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943	"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates"
XP_031622170.1	12	Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-72649	"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation"
XP_031631839.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_031632277.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339;Reactome: R-HSA-879415	"Asparagine N-linked glycosylation";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling"
XP_031635324.1	9	Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"MAP2K and MAPK activation";"mTOR signalling";"mTORC1-mediated signalling"
XP_031629424.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031629314.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031639771.1	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;Reactome: R-HSA-71737;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Glyphosate degradation III"
XP_031640745.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031635843.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031626608.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_031620746.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_031635535.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031625890.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_031631062.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031631607.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_031637973.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031627204.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031634453.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031633495.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_031635319.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_031629548.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_031621084.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_031627611.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_031622000.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes"
XP_031622388.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695	"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation"
XP_031638135.1	9	MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-6963	"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Ammonia assimilation cycle I"
XP_031640808.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs"
XP_031618541.1	15	MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Rubisco shunt";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Purine metabolism"
XP_031632865.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_031619596.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_031626268.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_031629901.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031618767.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031630311.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Signaling by Hippo";"Thermogenesis"
XP_031622612.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031638905.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585	"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence"
XP_031621139.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041	"Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle"
XP_031624800.1	28	Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862	"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Translesion synthesis by POLK"
XP_031638139.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_031621937.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031624310.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031640087.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_031638456.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_031623453.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031622096.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_031629968.1	8	KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-6545	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_031632903.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031640088.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_031618351.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_031631743.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_031631292.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_031632117.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_031631012.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031620809.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031617177.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_031627006.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_031627799.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_031624901.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031631733.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031621022.1	10	KEGG: 04150+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153	"mTOR signaling pathway";"Synthesis of PIPs at the plasma membrane";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"3-phosphoinositide biosynthesis";"PI3K-Akt signaling pathway";"Inositol phosphate metabolism"
XP_031622327.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031623002.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_031636394.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_031622997.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031622665.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_031625735.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031618206.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031641067.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031633463.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_031635261.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;MetaCyc: PWY-7511	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Protein ubiquitination"
XP_031633190.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_031625009.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_031626497.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs"
XP_031630600.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031640988.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031618613.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031627822.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031621486.1	12	MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Gluconeogenesis"
XP_031616907.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_031620839.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031631417.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031632870.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_031636198.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_031633565.1	30	Reactome: R-HSA-9614399;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;Reactome: R-HSA-198693;Reactome: R-HSA-6804758;Reactome: R-HSA-8948751;Reactome: R-HSA-199418;Reactome: R-HSA-211163;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1358803;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-6804759;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-8941332;Reactome: R-HSA-389513;Reactome: R-HSA-111447;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-8876198	"Regulation of localization of FOXO transcription factors";"Thermogenesis";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"AKT phosphorylates targets in the nucleus";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN stability and activity";"Negative regulation of the PI3K/AKT network";"AKT-mediated inactivation of FOXO1A";"Human cytomegalovirus infection";"Downregulation of ERBB2:ERBB3 signaling";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Association with Co-factors";"PI3K-Akt signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RUNX2 regulates genes involved in cell migration";"CTLA4 inhibitory signaling";"Activation of BAD and translocation to mitochondria";"mTOR signaling pathway";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"RAB GEFs exchange GTP for GDP on RABs"
XP_031628363.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555	"Regulation of signaling by CBL";"Downstream signal transduction";"MET receptor recycling";"MET activates RAP1 and RAC1"
XP_031635068.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_031626607.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031636631.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031640574.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_031617770.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_031618221.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031624201.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031636259.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031623750.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031636727.1	7	KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane"
XP_031627507.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_031639498.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031619819.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_031617824.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031630169.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_031626006.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031616909.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_031617434.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031631724.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_031616331.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031621922.1	13	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-2424491;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871809;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;Reactome: R-HSA-202433	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling";"Inositol phosphate metabolism";"FCERI mediated Ca+2 mobilization";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Generation of second messenger molecules"
XP_031626100.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_031638650.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_031640041.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_031618201.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031639068.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_031616640.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_031626500.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_031630923.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031636602.1	15	Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of MECP2 expression and activity"
XP_031630134.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_031621436.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_031622014.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-6807505	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA polymerase II transcribes snRNA genes"
XP_031635695.1	4	Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-1632852	"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy"
XP_031617046.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031627345.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_031625263.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_031622466.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_031632894.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_031626333.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031626641.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031627137.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-113507	"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_031626652.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031637419.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031624599.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_031617969.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_031632506.1	8	KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171	"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis"
XP_031622596.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031620428.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_031628920.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031634776.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_031626742.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_031630797.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_031622993.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031628002.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031619528.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031618022.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_031619102.1	3	MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5	"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_031629310.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031630106.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_031629840.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-392170;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418217	"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"ADP signalling through P2Y purinoceptor 12";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta"
XP_031623170.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031617091.1	14	MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_031631118.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031623329.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031626499.1	5	MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210	"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_031631061.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031635070.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_031618692.1	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_031626189.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031637294.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031640350.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_031633042.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_031631642.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031637488.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031622022.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_031639927.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031630055.1	13	Reactome: R-HSA-4341670;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695	"Defective NEU1 causes sialidosis";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation"
XP_031627937.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031624350.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031639854.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031631691.1	11	Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111457;Reactome: R-HSA-1268020;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-111463	"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria";"Mitochondrial protein import";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs"
XP_031626122.1	4	Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583;MetaCyc: PWY-6129	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis"
XP_031630348.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_031621955.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569	"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_031629322.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031638714.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_031626037.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031624435.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_031632868.1	14	MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_031626481.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031638138.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031640952.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031628003.1	29	Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-167158	"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex"
XP_031630777.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_031634832.1	18	MetaCyc: PWY-7226;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
XP_031626628.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_031622563.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_031622829.1	179	Reactome: R-HSA-182971;Reactome: R-HSA-8852276;Reactome: R-HSA-975957;Reactome: R-HSA-6781823;Reactome: R-HSA-9613829;Reactome: R-HSA-2672351;Reactome: R-HSA-1236382;Reactome: R-HSA-6782135;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-8866654;Reactome: R-HSA-179409;Reactome: R-HSA-1358803;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5654733;Reactome: R-HSA-5654727;Reactome: R-HSA-5357905;Reactome: R-HSA-1253288;Reactome: R-HSA-912631;Reactome: R-HSA-192823;Reactome: R-HSA-1169091;Reactome: R-HSA-2173791;Reactome: R-HSA-5685942;Reactome: R-HSA-9020702;Reactome: R-HSA-2173788;Reactome: R-HSA-8849469;Reactome: R-HSA-9014325;Reactome: R-HSA-5696395;Reactome: R-HSA-937041;Reactome: R-HSA-8875360;Reactome: R-HSA-5362768;Reactome: R-HSA-937039;Reactome: R-HSA-5205685;Reactome: R-HSA-5675221;Reactome: R-HSA-9637628;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-110312;Reactome: R-HSA-975110;Reactome: R-HSA-162588;Reactome: R-HSA-4641257;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-5358346;Reactome: R-HSA-8866652;Reactome: R-HSA-977225;Reactome: R-HSA-2691232;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-180585;Reactome: R-HSA-5654726;Reactome: R-HSA-9645460;Reactome: R-HSA-9604323;Reactome: R-HSA-175474;Reactome: R-HSA-69481;Reactome: R-HSA-72706;Reactome: R-HSA-5687128;Reactome: R-HSA-975956;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5654732;Reactome: R-HSA-8856828;Reactome: R-HSA-1799339;Reactome: R-HSA-400253;Reactome: R-HSA-8876493;Reactome: R-HSA-8948747;Reactome: R-HSA-1169408;Reactome: R-HSA-5696400;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5656121;Reactome: R-HSA-5693565;Reactome: R-HSA-2894862;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-445989;Reactome: R-HSA-5689896;Reactome: R-HSA-5675482;Reactome: R-HSA-110320;Reactome: R-HSA-180534;Reactome: R-HSA-5696394;Reactome: R-HSA-6791226;Reactome: R-HSA-937072;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-975144;Reactome: R-HSA-2979096;Reactome: R-HSA-3322077;Reactome: R-HSA-349425;Reactome: R-HSA-2559585;Reactome: R-HSA-4641263;Reactome: R-HSA-2122947;Reactome: R-HSA-8863795;Reactome: R-HSA-917729;Reactome: R-HSA-69541;Reactome: R-HSA-2559580;Reactome: R-HSA-975163;Reactome: R-HSA-211733;Reactome: R-HSA-156827;Reactome: R-HSA-937042;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-168928;Reactome: R-HSA-72764;Reactome: R-HSA-901032;Reactome: R-HSA-3134975;Reactome: R-HSA-1236974;Reactome: R-HSA-174490;Reactome: R-HSA-8951664;Reactome: R-HSA-5668541;Reactome: R-HSA-5696397;Reactome: R-HSA-5689603;Reactome: R-HSA-72689;Reactome: R-HSA-69017;Reactome: R-HSA-5693607;Reactome: R-HSA-2173796;Reactome: R-HSA-174178;Reactome: R-HSA-9615710;Reactome: R-HSA-5656169;Reactome: R-HSA-2559582;Reactome: R-HSA-3769402;Reactome: R-HSA-209543;Reactome: R-HSA-2565942;Reactome: R-HSA-6804756;Reactome: R-HSA-6804757;Reactome: R-HSA-69231;Reactome: R-HSA-9013507;Reactome: R-HSA-983168;Reactome: R-HSA-209560;Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-8856825;Reactome: R-HSA-2408557;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-450302;Reactome: R-HSA-532668;Reactome: R-HSA-6804760;Reactome: R-HSA-5689901;Reactome: R-HSA-205043;Reactome: R-HSA-5655862;Reactome: R-HSA-1295596;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-9646399;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-6807004;Reactome: R-HSA-5607764;Reactome: R-HSA-156902;Reactome: R-HSA-2173795;Reactome: R-HSA-9013973;Reactome: R-HSA-5357956;Reactome: R-HSA-174084;Reactome: R-HSA-6782210;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-168927;Reactome: R-HSA-69601;Reactome: R-HSA-9636383;Reactome: R-HSA-936964;Reactome: R-HSA-168638;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-174048;Reactome: R-HSA-3785653;Reactome: R-HSA-6781827;Reactome: R-HSA-5610780;Reactome: R-HSA-9033241;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-450321;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5689877;Reactome: R-HSA-936440	"EGFR downregulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of TC-NER Pre-Incision Complex";"Chaperone Mediated Autophagy";"Stimuli-sensing channels";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Dual incision in TC-NER";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"APC-Cdc20 mediated degradation of Nek2A";"Downregulation of ERBB2:ERBB3 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR2 signaling";"Regulation of TNFR1 signaling";"Downregulation of ERBB4 signaling";"Regulation of signaling by CBL";"Viral mRNA Translation";"Activation of NF-kappaB in B cells";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"HDR through Homologous Recombination (HRR)";"Interleukin-1 signaling";"Downregulation of TGF-beta receptor signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Formation of Incision Complex in GG-NER";"IKK complex recruitment mediated by RIP1";"InlB-mediated entry of Listeria monocytogenes into host cell";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"IRAK1 recruits IKK complex";"Pink/Parkin Mediated Mitophagy";"Negative regulation of MAPK pathway";"Modulation by Mtb of host immune system";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Translesion synthesis by REV1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Budding and maturation of HIV virion";"Degradation of AXIN";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Hedgehog ligand biogenesis";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Vif-mediated degradation of APOBEC3G";"Negative regulation of FGFR1 signaling";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of NOTCH4 signaling";"Assembly Of The HIV Virion";"G2/M Checkpoints";"GTP hydrolysis and joining of the 60S ribosomal subunit";"MAPK6/MAPK4 signaling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Hedgehog 'on' state";"Negative regulation of FGFR3 signaling";"Clathrin-mediated endocytosis";"SRP-dependent cotranslational protein targeting to membrane";"Circadian Clock";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of PTEN localization";"ISG15 antiviral mechanism";"Dual Incision in GG-NER";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Translesion synthesis by POLI";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ovarian tumor domain proteases";"Regulation of necroptotic cell death";"Translesion Synthesis by POLH";"Vpu mediated degradation of CD4";"DNA Damage Recognition in GG-NER";"Major pathway of rRNA processing in the nucleolus and cytosol";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Glycogen synthesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Oncogene Induced Senescence";"Regulation of FZD by ubiquitination";"NOTCH1 Intracellular Domain Regulates Transcription";"Downregulation of ERBB2 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Stabilization of p53";"Oxidative Stress Induced Senescence";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"L13a-mediated translational silencing of Ceruloplasmin expression";"IRAK2 mediated activation of TAK1 complex";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Eukaryotic Translation Termination";"ER Quality Control Compartment (ERQC)";"Regulation of innate immune responses to cytosolic DNA";"ER-Phagosome pathway";"Membrane binding and targetting of GAG proteins";"Neddylation";"TNFR2 non-canonical NF-kB pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"UCH proteinases";"Formation of a pool of free 40S subunits";"CDK-mediated phosphorylation and removal of Cdc6";"Processing of DNA double-strand break ends";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Late endosomal microautophagy";"Termination of translesion DNA synthesis";"Senescence-Associated Secretory Phenotype (SASP)";"Deactivation of the beta-catenin transactivating complex";"p75NTR recruits signalling complexes";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Degradation";"Cyclin D associated events in G1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Antigen processing: Ubiquitination & Proteasome degradation";"NF-kB is activated and signals survival";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Cargo recognition for clathrin-mediated endocytosis";"Selenocysteine synthesis";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"activated TAK1 mediates p38 MAPK activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of TP53 Activity through Methylation";"Metalloprotease DUBs";"NRIF signals cell death from the nucleus";"Translesion synthesis by POLK";"Spry regulation of FGF signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Aggrephagy";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Negative regulation of MET activity";"CLEC7A (Dectin-1) signaling";"Peptide chain elongation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"TICAM1-dependent activation of IRF3/IRF7";"TNFR1-induced NFkappaB signaling pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"TICAM1, RIP1-mediated IKK complex recruitment";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Prevention of phagosomal-lysosomal fusion";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"NOD1/2 Signaling Pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Cyclin B";"Myoclonic epilepsy of Lafora";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Degradation of GLI1 by the proteasome";"Peroxisomal protein import";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Josephin domain DUBs";"Negative regulators of DDX58/IFIH1 signaling"
XP_031626725.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031621456.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_031634165.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031623929.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-933541	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation"
XP_031626575.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031622195.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_031638851.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_031630602.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031625274.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_031628967.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Early Events"
XP_031623678.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031622485.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031640980.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031637140.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031627157.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031629305.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031625056.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_031638481.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031627190.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031630579.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_031621346.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031634016.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031635870.1	18	Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4	"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism"
XP_031629770.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031622088.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-3108214	"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins"
XP_031637359.1	10	MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587	"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)"
XP_031619230.1	14	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_031624942.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_031620069.1	6	KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-6922;MetaCyc: PWY-4981	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)"
XP_031618319.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031636638.1	29	Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_031628239.1	11	Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696397	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_031623229.1	182	Reactome: R-HSA-445989;Reactome: R-HSA-5689896;Reactome: R-HSA-5675482;Reactome: R-HSA-110320;Reactome: R-HSA-5696394;Reactome: R-HSA-180534;Reactome: R-HSA-6791226;Reactome: R-HSA-201681;Reactome: R-HSA-937072;Reactome: R-HSA-8948751;Reactome: R-HSA-975144;Reactome: R-HSA-2979096;Reactome: R-HSA-3322077;Reactome: R-HSA-349425;Reactome: R-HSA-2559585;Reactome: R-HSA-4641263;Reactome: R-HSA-8863795;Reactome: R-HSA-2122947;Reactome: R-HSA-69541;Reactome: R-HSA-917729;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-975956;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-1799339;Reactome: R-HSA-5654732;Reactome: R-HSA-8856828;Reactome: R-HSA-400253;Reactome: R-HSA-8876493;Reactome: R-HSA-8948747;Reactome: R-HSA-5696400;Reactome: R-HSA-1169408;Reactome: R-HSA-5678895;Reactome: R-HSA-5693565;Reactome: R-HSA-187577;Reactome: R-HSA-5656121;Reactome: R-HSA-2894862;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-8849469;Reactome: R-HSA-5696395;Reactome: R-HSA-9014325;Reactome: R-HSA-2173788;Reactome: R-HSA-937041;Reactome: R-HSA-8875360;Reactome: R-HSA-937039;Reactome: R-HSA-5362768;Reactome: R-HSA-5675221;Reactome: R-HSA-9637628;Reactome: R-HSA-5205685;Reactome: R-HSA-2644606;Reactome: R-HSA-110312;Reactome: R-HSA-975110;Reactome: R-HSA-2122948;Reactome: R-HSA-162588;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-8866652;Reactome: R-HSA-2691232;Reactome: R-HSA-977225;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-9633012;Reactome: R-HSA-180585;Reactome: R-HSA-5654726;Reactome: R-HSA-69481;Reactome: R-HSA-175474;Reactome: R-HSA-9604323;Reactome: R-HSA-9645460;Reactome: R-HSA-182971;Reactome: R-HSA-8852276;Reactome: R-HSA-9613829;Reactome: R-HSA-6781823;Reactome: R-HSA-2672351;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-6782135;Reactome: R-HSA-1236382;Reactome: R-HSA-72695;Reactome: R-HSA-179409;Reactome: R-HSA-8866654;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-1358803;Reactome: R-HSA-202424;Reactome: R-HSA-5654727;Reactome: R-HSA-5654733;Reactome: R-HSA-1253288;Reactome: R-HSA-5357905;Reactome: R-HSA-912631;Reactome: R-HSA-2173791;Reactome: R-HSA-1169091;Reactome: R-HSA-192823;Reactome: R-HSA-5685942;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-168927;Reactome: R-HSA-936964;Reactome: R-HSA-9636383;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-168638;Reactome: R-HSA-8939902;Reactome: R-HSA-174048;Reactome: R-HSA-3785653;Reactome: R-HSA-6781827;Reactome: R-HSA-9033241;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-450321;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-936440;Reactome: R-HSA-5689877;Reactome: R-HSA-5689901;Reactome: R-HSA-205043;Reactome: R-HSA-5655862;Reactome: R-HSA-1295596;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-9646399;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-6807004;Reactome: R-HSA-5607764;Reactome: R-HSA-9013973;Reactome: R-HSA-2173795;Reactome: R-HSA-156902;Reactome: R-HSA-6782210;Reactome: R-HSA-5357956;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-209543;Reactome: R-HSA-3769402;Reactome: R-HSA-6804756;Reactome: R-HSA-2565942;Reactome: R-HSA-6804757;Reactome: R-HSA-69231;Reactome: R-HSA-9013507;Reactome: R-HSA-983168;Reactome: R-HSA-209560;Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-8856825;Reactome: R-HSA-2408557;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-532668;Reactome: R-HSA-450302;Reactome: R-HSA-6804760;Reactome: R-HSA-2559580;Reactome: R-HSA-975163;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-937042;Reactome: R-HSA-156827;Reactome: R-HSA-168928;Reactome: R-HSA-8854050;Reactome: R-HSA-901032;Reactome: R-HSA-72764;Reactome: R-HSA-3134975;Reactome: R-HSA-1236974;Reactome: R-HSA-174490;Reactome: R-HSA-8951664;Reactome: R-HSA-5696397;Reactome: R-HSA-5668541;Reactome: R-HSA-72689;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-5693607;Reactome: R-HSA-72649;Reactome: R-HSA-2173796;Reactome: R-HSA-9615710;Reactome: R-HSA-174178;Reactome: R-HSA-5656169	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ovarian tumor domain proteases";"Regulation of necroptotic cell death";"Translesion Synthesis by POLH";"DNA Damage Recognition in GG-NER";"Vpu mediated degradation of CD4";"Major pathway of rRNA processing in the nucleolus and cytosol";"TCF dependent signaling in response to WNT";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of PTEN stability and activity";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Glycogen synthesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Oncogene Induced Senescence";"Regulation of FZD by ubiquitination";"Downregulation of ERBB2 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Stabilization of p53";"Endosomal Sorting Complex Required For Transport (ESCRT)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ub-specific processing proteases";"Hedgehog 'on' state";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of FGFR3 signaling";"Clathrin-mediated endocytosis";"Circadian Clock";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of PTEN localization";"Dual Incision in GG-NER";"ISG15 antiviral mechanism";"Defective CFTR causes cystic fibrosis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SCF(Skp2)-mediated degradation of p27/p21";"Translesion synthesis by POLI";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Formation of Incision Complex in GG-NER";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downregulation of TGF-beta receptor signaling";"IKK complex recruitment mediated by RIP1";"InlB-mediated entry of Listeria monocytogenes into host cell";"IRAK1 recruits IKK complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of MAPK pathway";"Modulation by Mtb of host immune system";"Pink/Parkin Mediated Mitophagy";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Translesion synthesis by REV1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Budding and maturation of HIV virion";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Amyloid fiber formation";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Vif-mediated degradation of APOBEC3G";"Negative regulation of FGFR1 signaling";"G2/M Checkpoints";"Assembly Of The HIV Virion";"Negative regulation of NOTCH4 signaling";"Alpha-protein kinase 1 signaling pathway";"EGFR downregulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Chaperone Mediated Autophagy";"Formation of TC-NER Pre-Incision Complex";"Stimuli-sensing channels";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dual incision in TC-NER";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Formation of the ternary complex, and subsequently, the 43S complex";"APC-Cdc20 mediated degradation of Nek2A";"E3 ubiquitin ligases ubiquitinate target proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downregulation of ERBB2:ERBB3 signaling";"Downstream TCR signaling";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR4 signaling";"Downregulation of ERBB4 signaling";"Regulation of TNFR1 signaling";"Regulation of signaling by CBL";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Activation of NF-kappaB in B cells";"Viral mRNA Translation";"HDR through Homologous Recombination (HRR)";"Interleukin-1 signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"TICAM1, RIP1-mediated IKK complex recruitment";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Prevention of phagosomal-lysosomal fusion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NOD1/2 Signaling Pathway";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Cyclin B";"Myoclonic epilepsy of Lafora";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Peroxisomal protein import";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Negative regulators of DDX58/IFIH1 signaling";"Josephin domain DUBs";"Metalloprotease DUBs";"NRIF signals cell death from the nucleus";"Translesion synthesis by POLK";"Spry regulation of FGF signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Aggrephagy";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Negative regulation of MET activity";"CLEC7A (Dectin-1) signaling";"TICAM1-dependent activation of IRF3/IRF7";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Peptide chain elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TNFR1-induced NFkappaB signaling pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"p75NTR recruits signalling complexes";"Deactivation of the beta-catenin transactivating complex";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of TP53 Degradation";"Cyclin D associated events in G1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Antigen processing: Ubiquitination & Proteasome degradation";"NF-kB is activated and signals survival";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Cargo recognition for clathrin-mediated endocytosis";"Selenocysteine synthesis";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"activated TAK1 mediates p38 MAPK activation";"Regulation of TP53 Activity through Methylation";"Oxidative Stress Induced Senescence";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"IRAK2 mediated activation of TAK1 complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER Quality Control Compartment (ERQC)";"Eukaryotic Translation Termination";"Regulation of innate immune responses to cytosolic DNA";"ER-Phagosome pathway";"Membrane binding and targetting of GAG proteins";"Neddylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TNFR2 non-canonical NF-kB pathway";"Formation of a pool of free 40S subunits";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Processing of DNA double-strand break ends";"Translation initiation complex formation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Late endosomal microautophagy";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Termination of translesion DNA synthesis"
XP_031618226.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031627383.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_031619244.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-975634	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Retinoid metabolism and transport"
XP_031627009.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_031629689.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_031633496.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_031635725.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031639846.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031625300.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031621999.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364	"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_031627329.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031619377.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031620748.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_031636313.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031628334.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031624130.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_031617658.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"O-linked glycosylation"
XP_031634074.1	16	Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-180585;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Vif-mediated degradation of APOBEC3G";"Tat-mediated HIV elongation arrest and recovery"
XP_031639074.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_031623694.1	42	Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886;Reactome: R-HSA-5693607;Reactome: R-HSA-5578749;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-212300;Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-8939236;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-2299718;Reactome: R-HSA-171306;Reactome: R-HSA-3214858;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Processing of DNA double-strand break ends";"Transcriptional regulation by small RNAs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"PRC2 methylates histones and DNA";"Meiotic synapsis";"DNA methylation";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Condensation of Prophase Chromosomes";"Packaging Of Telomere Ends";"RMTs methylate histone arginines";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)"
XP_031617497.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_031624918.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031630021.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031621475.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031621169.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031634249.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031636668.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_031625292.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031636776.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031620010.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031632752.1	3	KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"Glycine degradation";"One carbon pool by folate"
XP_031637727.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_031629974.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031632953.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_031636104.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_031637369.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031633664.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_031638672.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_031629462.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-913709;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins";"N-Glycan antennae elongation"
XP_031625606.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031617970.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_031625777.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_031621520.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_031641065.1	5	MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_031636484.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031634844.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555	"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events"
XP_031618075.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031638380.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_031638780.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_031630359.1	4	KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030	"Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis"
XP_031635101.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031640923.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031640999.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_031628631.1	31	MetaCyc: PWY-5989;Reactome: R-HSA-199220;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-8049;MetaCyc: PWY-7746;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;Reactome: R-HSA-75105;MetaCyc: PWY-7664;MetaCyc: PWY-6799;MetaCyc: PWY-8012;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-5971;MetaCyc: PWY-7723;MetaCyc: PWY-6282;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-5994;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113	"Stearate biosynthesis II (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bacterial bioluminescence";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Biotin metabolism";"Superpathway of mycolate biosynthesis"
XP_031620402.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031635559.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_031637507.1	57	Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257	"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Degradation of AXIN"
XP_031626377.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_031639252.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031631892.1	5	MetaCyc: PWY-7919;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_031628369.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031621556.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031639199.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031623310.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031616906.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_031630248.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_031620932.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_031619770.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_031621563.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_031627891.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031621462.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_031621553.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-7285;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_031635823.1	5	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031629307.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031626872.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_031634222.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031634958.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_031630622.1	5	KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;Reactome: R-HSA-389661;MetaCyc: PWY-6853	"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)"
XP_031631409.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031628345.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031636714.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_031637427.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_031621291.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031618078.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_031628500.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_031628836.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678	"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_031620338.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031627135.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation"
XP_031636382.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031617184.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031627126.1	13	MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-5123;MetaCyc: PWY-7736	"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis"
XP_031626886.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8948751	"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Neddylation";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity"
XP_031627160.1	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis"
XP_031638795.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_031632241.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031633564.1	30	Reactome: R-HSA-8876198;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-111447;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-8941332;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804759;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;Reactome: R-HSA-1358803;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-8948751;Reactome: R-HSA-199418;Reactome: R-HSA-6804758;Reactome: R-HSA-392451;Reactome: R-HSA-198693;Reactome: R-HSA-6804757;Reactome: R-HSA-9614399;KEGG: 04714+2.7.11.1	"RAB GEFs exchange GTP for GDP on RABs";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"CTLA4 inhibitory signaling";"Activation of BAD and translocation to mitochondria";"mTOR signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RUNX2 regulates genes involved in cell migration";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Association with Co-factors";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"Downregulation of ERBB2:ERBB3 signaling";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"AKT-mediated inactivation of FOXO1A";"Regulation of PTEN stability and activity";"Negative regulation of the PI3K/AKT network";"Regulation of TP53 Activity through Acetylation";"G beta:gamma signalling through PI3Kgamma";"AKT phosphorylates targets in the nucleus";"Regulation of TP53 Degradation";"Regulation of localization of FOXO transcription factors";"Thermogenesis"
XP_031629808.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_031637914.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031633315.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_031616330.1	6	MetaCyc: PWY-6368;MetaCyc: PWY-6580;Reactome: R-HSA-1660517;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.64	"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_031632991.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I"
XP_031637406.1	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
XP_031623773.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_031631760.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031617698.1	13	MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52	"Chitin degradation II (Vibrio)";"CS/DS degradation";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis"
XP_031625006.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_031618959.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031633342.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation"
XP_031632296.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031624312.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031625226.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_031640377.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031623181.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031620586.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466	"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis"
XP_031638434.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031618825.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031624105.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031627778.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_031631910.1	5	MetaCyc: PWY-7919;Reactome: R-HSA-4793954;Reactome: R-HSA-532668;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106	"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis"
XP_031634507.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_031640924.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031621258.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
XP_031639067.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_031636802.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031641034.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_031620481.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_031627926.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7559	"Glutathione metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway"
XP_031619328.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"Peptide chain elongation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_031621537.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031632481.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_031622660.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_031626325.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031626924.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031641232.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_031618507.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031628040.1	6	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_031626483.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031632665.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031622144.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031627419.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031637767.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031626419.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_031640822.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II"
XP_031632240.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031622196.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_031636552.1	10	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_031629721.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_031630926.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031627558.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6807505	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes"
XP_031628669.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_031622098.1	9	Reactome: R-HSA-5689603;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279	"UCH proteinases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer"
XP_031626421.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031635066.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_031619815.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"Transcription of the HIV genome"
XP_031640824.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001	"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_031621834.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031622913.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_031623626.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_031622662.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031628199.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_031638561.1	19	Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-983231;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-5627123;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-418885;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-8964616;Reactome: R-HSA-525793	"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"EGFR downregulation";"Factors involved in megakaryocyte development and platelet production";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"RHO GTPases activate PAKs";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"DCC mediated attractive signaling";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"G beta:gamma signalling through CDC42";"Myogenesis"
XP_031628233.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_031633027.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_031635093.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031624026.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031635567.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_031617308.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_031621246.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031628863.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-162594	"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle"
XP_031625662.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031619483.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031634713.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031636767.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031626864.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692	"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity"
XP_031636775.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031617948.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_031619768.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031626426.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC"
XP_031623333.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031619406.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031633511.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337	"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding"
XP_031624559.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031641229.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_031624485.1	6	Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-389661;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765	"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Glyoxylate metabolism and glycine degradation";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression"
XP_031622393.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870	"Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_031617301.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_031625420.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_031631943.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_031636996.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3	"Synthesis of PA";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism"
XP_031632283.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031639450.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031637694.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_031629313.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031617040.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_031630788.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031637424.1	13	MetaCyc: PWY-5538;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913	"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)"
XP_031633116.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031622775.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_031621172.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031624348.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_031634176.1	8	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_031636797.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031623340.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031616603.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_031629723.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_031618253.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031625387.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_031638424.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031629038.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031634294.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_031623609.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_031620855.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_031627691.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_031620487.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031640365.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_031635549.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031637593.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031622513.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_031622160.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031632657.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_031620616.1	7	Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22	"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_031635237.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031620439.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_031618516.1	1	Reactome: R-HSA-419771	"Opsins"
XP_031622142.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031637311.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_031617057.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_031623440.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031621235.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031621811.1	7	Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214;Reactome: R-HSA-983168;Reactome: R-HSA-69473;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)"
XP_031616936.1	58	KEGG: 00650+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7606;Reactome: R-HSA-77350;Reactome: R-HSA-77346;MetaCyc: PWY-6583;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-5138;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-7216;KEGG: 00362+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-1361;MetaCyc: PWY-7007;Reactome: R-HSA-1482798;MetaCyc: PWY-6883;KEGG: 00280+4.2.1.17;KEGG: 00720+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00903+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;Reactome: R-HSA-77288;KEGG: 00930+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00410+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-6435;MetaCyc: PWY-7401;MetaCyc: PWY-7094;KEGG: 00380+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;Reactome: R-HSA-77348;MetaCyc: PWY-5789;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7654	"Butanoate metabolism";"Caprolactam degradation";"Androstenedione degradation";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Spodoptera littoralis pheromone biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Pyruvate fermentation to butanol I";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid degradation";"Tryptophan metabolism";"Phenylalanine metabolism";"Fatty acid elongation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Benzoate degradation";"Benzoate degradation";"Fatty acid elongation";"Benzoyl-coa degradation I (aerobic)";"Methyl ketone biosynthesis (engineered)";"Acyl chain remodeling of CL";"Pyruvate fermentation to butanol II (engineered)";"Valine, leucine and isoleucine degradation";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid degradation";"Limonene and pinene degradation";"Lysine degradation";"Fermentation to 2-methylbutanoate";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Caprolactam degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"beta-Alanine metabolism";"Geraniol degradation";"Glutaryl-coa degradation";"Butanoate metabolism";"Lysine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"4-hydroxybenzoate biosynthesis III (plants)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid salvage";"Tryptophan metabolism";"Toluene degradation";"2-methylpropene degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aminobenzoate degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"(8E,10E)-dodeca-8,10-dienol biosynthesis"
XP_031634923.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031625785.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_031633848.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031620473.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_031616406.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031638428.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_031619620.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031638993.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031641064.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system"
XP_031620023.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_031620376.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031632821.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031617504.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642	"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_031619594.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_031629679.1	8	KEGG: 00030+5.3.1.6;Reactome: R-HSA-5659996;Reactome: R-HSA-6791461;Reactome: R-HSA-71336;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6	"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism"
XP_031633007.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031641193.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031624465.1	7	KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921	"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_031626576.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_031629082.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_031630624.1	5	Reactome: R-HSA-70688;Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88	"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism"
XP_031635014.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031631643.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031632643.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6722	"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Candicidin biosynthesis"
XP_031630960.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031635075.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031618731.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031636642.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031635612.1	42	Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-606279;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-3214841;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-2299718;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-69473;Reactome: R-HSA-212300;Reactome: R-HSA-5578749;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-110331;Reactome: R-HSA-2559580;Reactome: R-HSA-201722;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632	"SUMOylation of chromatin organization proteins";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"PKMTs methylate histone lysines";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"Condensation of Prophase Chromosomes";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"G2/M DNA damage checkpoint";"PRC2 methylates histones and DNA";"Transcriptional regulation by small RNAs";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged purine";"Oxidative Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"DNA methylation";"HDACs deacetylate histones";"Meiotic synapsis"
XP_031628915.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031633665.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_031640828.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_031622063.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031624576.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031624227.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031633142.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_031638451.1	7	KEGG: 00564+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;MetaCyc: PWY-7625	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_031628901.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031627035.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_031630175.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_031618436.1	11	Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700	"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_031621069.1	7	KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_031628304.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_031636383.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031638559.1	19	Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-114604;Reactome: R-HSA-3928662;Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-983231;Reactome: R-HSA-182971;Reactome: R-HSA-418885;Reactome: R-HSA-8950505;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-5627123;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"GPVI-mediated activation cascade";"EPHB-mediated forward signaling";"Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"Factors involved in megakaryocyte development and platelet production";"EGFR downregulation";"DCC mediated attractive signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"RHO GTPases activate PAKs";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_031638175.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031620426.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_031617757.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_031621122.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031617031.1	5	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_031640717.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031634856.1	6	Reactome: R-HSA-389661;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-75105	"Glyoxylate metabolism and glycine degradation";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis"
XP_031631293.1	3	MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695	"Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation"
XP_031617337.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031626833.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031620260.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031617470.1	4	MetaCyc: PWY-6972;Reactome: R-HSA-5679001;Reactome: R-HSA-382556;Reactome: R-HSA-189483	"Oleandomycin activation/inactivation";"Defective ABCC2 causes Dubin-Johnson syndrome";"ABC-family proteins mediated transport";"Heme degradation"
XP_031637177.1	30	Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-2644607;Reactome: R-HSA-1170546;Reactome: R-HSA-983168;Reactome: R-HSA-2644606;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-8951664	"Downstream TCR signaling";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Prolactin receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Neddylation"
XP_031618950.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031619026.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031640039.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031628010.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795	"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity"
XP_031625810.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_031619722.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031619713.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031631063.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031631692.1	11	KEGG: 04714+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-8866654;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Cytosolic sensors of pathogen-associated DNA";"E3 ubiquitin ligases ubiquitinate target proteins";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"mTOR signaling pathway";"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031632152.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031631460.1	11	Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236	"Myogenesis";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_031636393.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_031636600.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519	"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression"
XP_031636603.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459	"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031619291.1	20	KEGG: 04714+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357	"Thermogenesis";"mTOR signalling";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Amino acids regulate mTORC1";"Relaxin signaling pathway";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling"
XP_031631198.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031617656.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"O-linked glycosylation"
XP_031630755.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031627202.1	42	MetaCyc: PWY-5177;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00903+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5136;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5789;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7094;MetaCyc: PWY-7401;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-6946;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-6863;MetaCyc: PWY-6583;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-7656;KEGG: 00640+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6944;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7007;MetaCyc: PWY-1361;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216	"Glutaryl-coa degradation";"Geraniol degradation";"beta-Alanine metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Carbon fixation pathways in prokaryotes";"Fermentation to 2-methylbutanoate";"Limonene and pinene degradation";"Lysine degradation";"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Aminobenzoate degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Toluene degradation";"2-methylpropene degradation";"Fatty acid salvage";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"Fatty acid elongation";"Phenylalanine metabolism";"Fatty acid degradation";"Tryptophan metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol I";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Spodoptera littoralis pheromone biosynthesis";"Propanoate metabolism";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Androstenedione degradation";"Caprolactam degradation";"Pyruvate fermentation to butanol II (engineered)";"Methyl ketone biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"Benzoate degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)"
XP_031631388.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_031635155.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_031640391.1	14	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_031632897.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031638171.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_031638162.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_031640540.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031621539.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031619987.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_031640989.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_031641131.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031626372.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031632203.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_031632190.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_031620615.1	7	KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_031624626.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_031630436.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_031629692.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031627742.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_031636787.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031631803.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031635098.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031629687.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_031627423.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_031633473.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_031631467.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785	"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Neddylation";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome"
XP_031636963.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031638676.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031636392.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031638143.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_031622998.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_031633008.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031639999.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031631601.1	13	KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation"
XP_031632531.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031632168.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_031617185.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031627713.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_031626026.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031629522.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031630516.1	6	Reactome: R-HSA-3322077;MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18	"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism"
XP_031626733.1	12	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-5250924	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression"
XP_031621307.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_031629117.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Activation of RAC1";"Thermogenesis"
XP_031631860.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031632732.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031641201.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_031633571.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031628504.1	56	Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702	"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Neddylation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling"
XP_031623134.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031640580.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_031623345.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031638246.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031623093.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_031616687.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031623269.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031621962.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-349425	"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_031629459.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_031620466.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
XP_031624406.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031638272.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_031617074.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_031639085.1	19	Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;Reactome: R-HSA-71403;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-1622	"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Formaldehyde assimilation I (serine pathway)"
XP_031619124.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_031620873.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031618017.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_031628554.1	11	Reactome: R-HSA-9013508;Reactome: R-HSA-72163;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"NOTCH3 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_031630438.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_031636472.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031636002.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_031622600.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031631394.1	6	MetaCyc: PWY-7346;MetaCyc: PWY-7820;Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22	"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism"
XP_031622086.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110329	"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine"
XP_031627360.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031641286.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_031627968.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_031627343.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_031630030.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031636267.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_031636764.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031621193.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031624915.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_031638298.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_031616334.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031637899.1	18	KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482925	"alpha-Linolenic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PG"
XP_031621247.1	9	Reactome: R-HSA-110330;Reactome: R-HSA-5649702;Reactome: R-HSA-9656256;Reactome: R-HSA-110329;Reactome: R-HSA-9656255;Reactome: R-HSA-9657050;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Processing";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Binding";"Defective OGG1 Localization";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine"
XP_031633308.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031621942.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031622026.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_031633778.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_031641041.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_031631719.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031632946.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_031617814.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_031628054.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031626013.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_031618471.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_031632373.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_031618318.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_031628991.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031626838.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031626342.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031640729.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031638431.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_031628819.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_031619995.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_031636389.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_031626104.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_031635668.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031633155.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031632275.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_031623751.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031624372.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_031622586.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031637848.1	9	MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation"
XP_031638655.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes"
XP_031636158.1	10	Reactome: R-HSA-432722;Reactome: R-HSA-437239;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-166016;Reactome: R-HSA-196025;Reactome: R-HSA-203641;Reactome: R-HSA-177504;Reactome: R-HSA-432720;Reactome: R-HSA-2132295	"Golgi Associated Vesicle Biogenesis";"Recycling pathway of L1";"Gap junction degradation";"Clathrin-mediated endocytosis";"Toll Like Receptor 4 (TLR4) Cascade";"Formation of annular gap junctions";"NOSTRIN mediated eNOS trafficking";"Retrograde neurotrophin signalling";"Lysosome Vesicle Biogenesis";"MHC class II antigen presentation"
XP_031617980.1	7	Reactome: R-HSA-74217;MetaCyc: PWY-7807;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6605;MetaCyc: PWY-6610;MetaCyc: PWY-7805;Reactome: R-HSA-6798695	"Purine salvage";"Glyphosate degradation III";"Purine metabolism";"Adenine and adenosine salvage II";"Adenine salvage";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation"
XP_031636933.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031622376.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_031619067.1	8	KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-6556;MetaCyc: PWY-7181;MetaCyc: PWY-7193;Reactome: R-HSA-6798695	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation"
XP_031620810.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031638291.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031627773.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_031620078.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031628824.1	8	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;MetaCyc: PWY-7221	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis"
XP_031622592.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031618468.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031636769.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031631638.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_031617271.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031631015.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031636777.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031631705.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031624247.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031634825.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_031639760.1	5	KEGG: 00520+2.5.1.7;KEGG: 00550+2.5.1.7;MetaCyc: PWY-7953;MetaCyc: PWY-6386;MetaCyc: PWY-6387	"Amino sugar and nucleotide sugar metabolism";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)"
XP_031623794.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_031631739.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_031619891.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_031634317.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031616550.1	13	MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-6842;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061	"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione metabolism";"Glutathione-mediated detoxification I"
XP_031630341.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_031633774.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_031622338.1	10	Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807	"HS-GAG degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_031629425.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031638137.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_031630521.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_031624311.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031638797.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031633811.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031620356.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_031627760.1	7	MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8	"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism"
XP_031626520.1	9	KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061	"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I"
XP_031637292.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031637996.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031633298.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553	"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs"
XP_031636007.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_031637994.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_031617049.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_031633153.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031617594.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_031629426.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031626312.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031625660.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_031640922.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_031625514.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_031638960.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_031626284.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_031633156.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_031632335.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031628104.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031635097.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031640608.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_031631646.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031630565.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"mTOR signalling"
XP_031624408.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_031626921.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031619066.1	8	MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7193	"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I"
XP_031630519.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031635387.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031630504.1	10	Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563	"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription"
XP_031640182.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_031622878.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031619897.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_031638817.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_031621262.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031624246.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031640025.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031621020.1	10	KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04070+2.7.1.153	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"3-phosphoinositide biosynthesis";"PI3K-Akt signaling pathway";"Inositol phosphate metabolism";"mTOR signaling pathway";"Synthesis of PIPs at the plasma membrane";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Phosphatidylinositol signaling system"
XP_031635747.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031635819.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031622906.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_031622908.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_031624848.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_031640882.1	1	KEGG: 00910+4.2.1.104	"Nitrogen metabolism"
XP_031632546.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_031616592.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72702	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition"
XP_031619502.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031631941.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031635929.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031635378.1	6	Reactome: R-HSA-8868766;MetaCyc: PWY-6829;Reactome: R-HSA-6785470;MetaCyc: PWY-7286;Reactome: R-HSA-6787450;MetaCyc: PWY-7285	"rRNA processing in the mitochondrion";"Trna methylation (yeast)";"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis"
XP_031636768.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031638990.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_031630039.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031632089.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN"
XP_031616402.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031633621.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781	"Phase I - Functionalization of compounds";"Xenobiotics";"Endogenous sterols";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression"
XP_031632284.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031639745.1	9	Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809	"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization"
XP_031640599.1	3	KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_031627134.1	4	Reactome: R-HSA-4755609;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_031626553.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_031627644.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031619322.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_031625666.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031622051.1	5	Reactome: R-HSA-3656237;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928	"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis"
XP_031626113.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_031630527.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_031639982.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031630497.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031628131.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_031626178.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_031636168.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031632486.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_031638656.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585	"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence"
XP_031616713.1	7	Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61	"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_031616822.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_031636391.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031616742.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031624818.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031628876.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031625633.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031640180.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_031625062.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_031624353.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031617508.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_031628921.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031632640.1	6	MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-4381;Reactome: R-HSA-196780	"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism"
XP_031630166.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_031629817.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_031640395.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_031617973.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_031628011.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795	"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity"
XP_031622440.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031617192.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031634103.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_031633733.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism"
XP_031632929.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031624431.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression"
XP_031627906.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_031618567.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031622543.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031635666.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_031632183.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_031628249.1	20	Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7858	"Peroxisomal protein import";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II"
XP_031629999.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031620939.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031632365.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_031631888.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031627034.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_031625722.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_031620897.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_031630564.1	5	Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571	"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation"
XP_031634049.1	18	KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_031630478.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167200	"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_031632571.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031622860.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031619525.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_031635388.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031640618.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_031638463.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031624852.1	10	MetaCyc: PWY-7921;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719377;MetaCyc: PWY-7979;Reactome: R-HSA-913709;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;MetaCyc: PWY-7661;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"N-Glycan biosynthesis";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation of mucins";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_031625665.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031638092.1	6	Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-389661;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765	"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Glyoxylate metabolism and glycine degradation";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression"
XP_031631144.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_031618235.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031632489.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_031617456.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031616408.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism"
XP_031636804.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031641287.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_031639662.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_031630184.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031633083.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_031638955.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;MetaCyc: PWY-7511	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination"
XP_031637403.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031632622.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031638890.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_031626663.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031619573.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_031629903.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031630731.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031630414.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-163615	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"DARPP-32 events";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation"
XP_031622579.1	5	Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221	"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway"
XP_031627610.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_031627901.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-171319;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-201722;Reactome: R-HSA-606279	"Ub-specific processing proteases";"Telomere Extension By Telomerase";"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_031622897.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_031618247.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031619604.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_031620944.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_031621280.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031632915.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949664	"Mitochondrial protein import";"Processing of SMDT1"
XP_031623870.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031622796.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_031628342.1	20	Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5651801	"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair"
XP_031627608.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-141444	"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_031624652.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_031633001.1	5	Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3	"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_031625227.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031617956.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_031626724.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_031639483.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_031621953.1	16	Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519	"Oncogene Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression"
XP_031626874.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_031626862.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031627922.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II"
XP_031626390.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031619496.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031619900.1	16	Reactome: R-HSA-1251985;Reactome: R-HSA-1250342;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-1963640;Reactome: R-HSA-1236394;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1250347	"Nuclear signaling by ERBB4";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"GRB2 events in ERBB2 signaling";"Signaling by ERBB4";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB4 signaling"
XP_031636524.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031636728.1	7	KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;MetaCyc: PWY-6352	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis"
XP_031635321.1	5	Reactome: R-HSA-193048;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_031634947.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_031638403.1	15	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence"
XP_031616910.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_031622386.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870	"Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_031616617.1	5	MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_031640479.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031625022.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_031625941.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state"
XP_031639069.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_031622556.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031617772.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_031636913.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031633280.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031619131.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031630066.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex"
XP_031617499.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_031623064.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031623766.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031635130.1	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781	"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis"
XP_031632162.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031618402.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031637358.1	14	Reactome: R-HSA-1632852;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5620924;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Macroautophagy";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Intraflagellar transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_031616607.1	3	MetaCyc: PWY-6100;Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8	"L-carnitine biosynthesis";"Carnitine synthesis";"Lysine degradation"
XP_031618614.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031616976.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031618171.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_031616958.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031628913.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031639218.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_031621565.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031636553.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174184	"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_031621464.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51	"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Glycerolipid metabolism"
XP_031621993.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex"
XP_031629771.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031624757.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031632998.1	14	MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_031623539.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_031638106.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031629993.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_031631678.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031625728.1	10	KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41	"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis"
XP_031620209.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031626020.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031630772.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031634487.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-180024	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"DARPP-32 events"
XP_031619804.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_031634603.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_031638444.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_031628200.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_031623630.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031619974.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_031620427.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_031616365.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_031627944.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_031640464.1	20	MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;Reactome: R-HSA-163765;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5913;Reactome: R-HSA-1268020;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-6728	"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"ChREBP activates metabolic gene expression";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Mitochondrial protein import";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Methylaspartate cycle"
XP_031620214.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_031622909.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_031618569.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031631716.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031618299.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031616975.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031633440.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_031640690.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031627555.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_031623857.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_031629171.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939236	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_031629316.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031632557.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_031637766.1	13	MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497	"Folate transformations II (plants)";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)"
XP_031635131.1	4	Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781	"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis"
XP_031618759.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism"
XP_031625313.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_031628242.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_031618508.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031619778.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031618440.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_031630333.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_031616618.1	5	MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_031638180.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031633484.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031627880.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031620148.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031622299.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_031626232.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031626566.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_031622898.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_031626870.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_031630494.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II"
XP_031635260.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;MetaCyc: PWY-7511	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Protein ubiquitination"
XP_031634803.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_031622642.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_031630998.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-6798695	"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Neutrophil degranulation"
XP_031638448.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_031640364.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_031618619.1	8	Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Ion channel transport";"Photosynthesis";"Oxidative phosphorylation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_031627081.1	4	Reactome: R-HSA-2408557;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_031617835.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_031631711.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031620791.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031624072.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_031641038.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_031633913.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031632744.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483	"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_031625320.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031624453.1	7	KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921	"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_031620763.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031625240.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837	"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation"
XP_031633670.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_031630977.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events"
XP_031635632.1	4	Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping"
XP_031638122.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_031637892.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-191859	"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"snRNP Assembly"
XP_031641007.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_031625431.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031621949.1	16	Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-426496	"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs"
XP_031631907.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031635515.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031625669.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031640909.1	11	MetaCyc: PWY-6608;MetaCyc: PWY-7185;MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7821;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-5695;MetaCyc: PWY-6607;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6596	"Guanosine nucleotides degradation III";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_031625279.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_031631389.1	8	MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086	"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_031640381.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031639339.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031633137.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_031632986.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657	"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes"
XP_031635156.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_031621119.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_031632269.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031618812.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031636260.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_031629740.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031629507.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_031624592.1	5	MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;MetaCyc: PWY-5531;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis"
XP_031622194.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_031625485.1	25	Reactome: R-HSA-8941858;Reactome: R-HSA-8939246;Reactome: R-HSA-8951936;Reactome: R-HSA-8939242;Reactome: R-HSA-8931987;Reactome: R-HSA-8941333;Reactome: R-HSA-8941284;Reactome: R-HSA-8939236;Reactome: R-HSA-8877330;Reactome: R-HSA-8939245;Reactome: R-HSA-9616222;Reactome: R-HSA-8941332;Reactome: R-HSA-8939247;Reactome: R-HSA-8934593;Reactome: R-HSA-8878166;Reactome: R-HSA-8949275;Reactome: R-HSA-8951911;Reactome: R-HSA-8935964;Reactome: R-HSA-8939256;Reactome: R-HSA-8939243;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8941326;Reactome: R-HSA-8939902;Reactome: R-HSA-8940973	"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in BCR signaling";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation by RUNX2";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"RUNX2 regulates bone development";"Regulation of RUNX2 expression and activity";"RUNX2 regulates osteoblast differentiation"
XP_031640102.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031617053.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031623523.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031639902.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031627084.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031627291.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_031636667.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_031639352.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_031622876.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031626341.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921	"Downstream signal transduction";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation"
XP_031636395.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_031630498.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031619035.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031626531.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031631251.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031636507.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031622754.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_031639248.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031626376.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_031633529.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_031636321.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031617398.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031619782.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031635092.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031626275.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031632276.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_031631202.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031621432.1	5	MetaCyc: PWY-6168;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-7863	"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis"
XP_031637859.1	6	MetaCyc: PWY-2941;MetaCyc: PWY-5097;KEGG: 00300+4.3.3.7;KEGG: 00261+4.3.3.7;MetaCyc: PWY-2942;MetaCyc: PWY-8088	"L-lysine biosynthesis II";"L-lysine biosynthesis VI";"Lysine biosynthesis";"Monobactam biosynthesis";"L-lysine biosynthesis III";"Dipicolinate biosynthesis"
XP_031619794.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_031633533.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_031637691.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_031618597.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_031619398.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031630878.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031636649.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031628001.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_031628124.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_031626727.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_031638745.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_031624934.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_031618494.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031624909.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_031638446.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_031622808.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_031632177.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_031636851.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031626290.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031635651.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_031629906.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031632208.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_031637885.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_031628238.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031626484.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031629123.1	9	MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_031625674.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_031634431.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_031632577.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031632912.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031630863.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031621958.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031627620.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519	"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression"
XP_031634909.1	5	Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-381038	"Hedgehog ligand biogenesis";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes"
XP_031639452.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031631612.1	26	Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"HCMV Early Events";"Recycling pathway of L1";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"Kinesins";"MHC class II antigen presentation";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_031616847.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_031627835.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031636950.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_031627966.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_031627576.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_031621487.1	12	Reactome: R-HSA-70263;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6142	"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_031623177.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031618716.1	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_031621198.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031640040.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_031632972.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031628635.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031640738.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031621684.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031618498.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_031622917.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031640929.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031632838.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_031630738.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_031628112.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_031640709.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031629366.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031626102.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_031623270.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031625019.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_031625298.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031629478.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031623330.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031623355.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_031617528.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_031616418.1	14	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-975634;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism"
XP_031629484.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031630232.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_031628497.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_031637779.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_031624939.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031623315.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_031636782.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031624874.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_031622652.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031633281.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031623679.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031621714.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031626882.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_031623227.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031635960.1	2	Reactome: R-HSA-114608;Reactome: R-HSA-2132295	"Platelet degranulation";"MHC class II antigen presentation"
XP_031633566.1	30	Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;KEGG: 05163+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-8948751;Reactome: R-HSA-199418;Reactome: R-HSA-6804758;Reactome: R-HSA-392451;Reactome: R-HSA-198693;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-8876198;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389513;KEGG: 04150+2.7.11.1;Reactome: R-HSA-111447;Reactome: R-HSA-9634638;Reactome: R-HSA-8941332;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69656;Reactome: R-HSA-6804759;Reactome: R-HSA-69202;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920	"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"Human cytomegalovirus infection";"AKT-mediated inactivation of FOXO1A";"Regulation of PTEN stability and activity";"Negative regulation of the PI3K/AKT network";"Regulation of TP53 Activity through Acetylation";"G beta:gamma signalling through PI3Kgamma";"AKT phosphorylates targets in the nucleus";"Regulation of TP53 Degradation";"Thermogenesis";"Regulation of localization of FOXO transcription factors";"RAB GEFs exchange GTP for GDP on RABs";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"CTLA4 inhibitory signaling";"mTOR signaling pathway";"Activation of BAD and translocation to mitochondria";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RUNX2 regulates genes involved in cell migration";"PI3K-Akt signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Association with Co-factors";"Cyclin E associated events during G1/S transition";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability"
XP_031630493.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-4061	"Glutathione metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I"
XP_031617500.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642	"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_031622282.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031630570.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031627207.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031617755.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_031626645.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_031640245.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism"
XP_031621211.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031624793.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031617851.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_031631046.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031626482.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031622216.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_031640974.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_031619603.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_031638309.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_031638379.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031640488.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031638358.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_031625639.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031616974.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031634256.1	4	KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_031638685.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_031640734.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031618915.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_031617051.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_031634343.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031629884.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_031627330.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031627259.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_031636931.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122	"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis"
XP_031622870.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events"
XP_031625855.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_031632367.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031618202.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031621208.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_031627945.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_031628111.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_031622046.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_031626003.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_031627983.1	29	Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-73776	"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape"
XP_031624908.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_031620301.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031639796.1	13	Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-983695	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_031628829.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_031628988.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031632176.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_031620850.1	18	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7187;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7184	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_031618168.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031631675.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031621815.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031629160.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031629139.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031636167.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_031625014.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_031632745.1	10	Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354	"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy"
XP_031627509.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031627446.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031630008.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031618897.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031622152.1	12	Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-1169408	"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"ISG15 antiviral mechanism"
XP_031639666.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II"
XP_031627119.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031635026.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism"
XP_031637429.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_031625016.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_031632106.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_031633861.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031623589.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_031636228.1	13	KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206308;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4341670;MetaCyc: PWY-6807;Reactome: R-HSA-2022857	"Glycosaminoglycan degradation";"Neutrophil degranulation";"Sphingolipid metabolism";"HS-GAG degradation";"Glycosphingolipid metabolism";"Galactose metabolism";"Sialic acid metabolism";"Other glycan degradation";"MPS IV - Morquio syndrome B";"Glycosphingolipid biosynthesis - ganglio series";"Defective NEU1 causes sialidosis";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation"
XP_031626024.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_031636780.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031620393.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031640397.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4	"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism"
XP_031639443.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031625102.1	4	MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism"
XP_031628525.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_031640044.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031623016.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031632797.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031638413.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031631209.1	6	Reactome: R-HSA-8951664;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472	"Neddylation";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_031622905.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_031629091.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_031635117.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_031621439.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_031627573.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_031626697.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes"
XP_031626012.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031636795.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031634976.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031639883.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031631649.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031640465.1	20	MetaCyc: PWY-5690;Reactome: R-HSA-6798695;Reactome: R-HSA-163765;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7384;Reactome: R-HSA-1268020;MetaCyc: PWY-5913;MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8	"TCA cycle II (plants and fungi)";"Neutrophil degranulation";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Mitochondrial protein import";"Partial TCA cycle (obligate autotrophs)";"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)"
XP_031620374.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031641053.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_031627780.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_031632679.1	12	MetaCyc: PWY-2821;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;MetaCyc: PWY-6842	"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Tryptophan catabolism";"Glutathione-mediated detoxification II"
XP_031620966.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_031618192.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_031634681.1	30	Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-69231;Reactome: R-HSA-2644607;Reactome: R-HSA-1170546;Reactome: R-HSA-2644606;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-9604323;Reactome: R-HSA-195253	"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Cyclin D associated events in G1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Neddylation";"Downstream TCR signaling";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex"
XP_031617904.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_031617231.1	10	MetaCyc: PWY-7909;MetaCyc: PWY-5030;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-1722	"Formaldehyde oxidation VII (THF pathway)";"L-histidine degradation III";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate"
XP_031633510.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-432142	"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL"
XP_031622050.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)"
XP_031621441.1	10	KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"RSK activation";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031639087.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-75105	"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis"
XP_031622911.1	5	KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22	"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_031637781.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_031621493.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_031632734.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031627681.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_031627026.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031633237.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_031624711.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_031628827.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Purine metabolism";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_031630315.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031624218.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031618949.1	7	MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;Reactome: R-HSA-1660662	"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_031635742.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_031625857.1	9	MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-6703	"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis"
XP_031626073.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism"
XP_031629658.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031623656.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031640472.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031621322.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;KEGG: 00906+2.5.1.32+5.5.1.19;MetaCyc: PWY-7938;MetaCyc: PWY-7939;MetaCyc: PWY-7947;MetaCyc: PWY-5943;MetaCyc: PWY-7591;MetaCyc: PWY-6279;MetaCyc: PWY-5947	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Carotenoid biosynthesis";"Isorenieratene biosynthesis I (actinobacteria)";"Chlorobactene biosynthesis";"Flexixanthin biosynthesis";"Beta-carotene biosynthesis";"Okenone biosynthesis";"Myxol-2' fucoside biosynthesis";"Lutein biosynthesis"
XP_031635410.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031620515.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_031631700.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031628953.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_031623139.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_031640383.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031616420.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031641254.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-9614657	"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes"
XP_031636123.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031623483.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031629775.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_031637436.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_031635178.1	15	Reactome: R-HSA-1227986;Reactome: R-HSA-9665247;Reactome: R-HSA-9665233;Reactome: R-HSA-9664565;Reactome: R-HSA-9665244;Reactome: R-HSA-8863795;Reactome: R-HSA-9665250;Reactome: R-HSA-9652282;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-9665245;Reactome: R-HSA-9665251;Reactome: R-HSA-5637810;Reactome: R-HSA-9665246;Reactome: R-HSA-9665249	"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to sapitinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to AEE788";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to afatinib"
XP_031635398.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031622558.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031636384.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031630697.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_031631701.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031632774.1	6	Reactome: R-HSA-389661;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"Glyoxylate metabolism and glycine degradation";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_031624134.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_031640382.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031623498.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031626069.1	7	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-110362	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair"
XP_031618705.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031629138.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031628990.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031618216.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031617647.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031621383.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031629320.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031635111.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_031624245.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031617189.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031625938.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state"
XP_031625078.1	6	MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III"
XP_031633256.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031630272.1	14	Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5656121	"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI"
XP_031617259.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001	"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade"
XP_031637446.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031640376.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031623771.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031630044.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031637090.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_031620961.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"DNA replication initiation";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis"
XP_031633214.1	9	Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-1362277;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_031626717.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_031641039.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031626358.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_031618218.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031627570.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_031638853.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_031638509.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_031619401.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031617563.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-5620924;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Intraflagellar transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Macroautophagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase"
XP_031639250.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031632534.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_031622857.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_031620790.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031640827.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031624313.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031619901.1	16	Reactome: R-HSA-1250347;Reactome: R-HSA-1236394;Reactome: R-HSA-1963640;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1250342;Reactome: R-HSA-1251985	"SHC1 events in ERBB4 signaling";"Signaling by ERBB4";"GRB2 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB4 signaling";"Nuclear signaling by ERBB4"
XP_031620614.1	7	KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines"
XP_031630446.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_031622809.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_031639549.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031637224.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031639472.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-3371571	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"mTOR signalling";"HSF1-dependent transactivation"
XP_031627679.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031628968.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_031621659.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031624360.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031626318.1	9	Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_031630591.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031630489.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_031635481.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_031638422.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031635987.1	13	Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171	"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Integrin cell surface interactions";"Signaling by PDGF";"ECM proteoglycans";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions"
XP_031629769.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031621133.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031639168.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Sialic acid metabolism";"Neutrophil degranulation"
XP_031637650.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_031622664.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_031623859.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_031631741.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_031636791.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031622938.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031618146.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031623188.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031617105.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_031625806.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-389513	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling"
XP_031637497.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031630157.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031627019.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_031637618.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031617395.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_031617338.1	7	KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;MetaCyc: PWY-5188;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism"
XP_031627995.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_031635110.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_031617218.1	4	Reactome: R-HSA-1362409;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250	"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_031636010.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_031617887.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_031623112.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031632333.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031617882.1	17	Reactome: R-HSA-6796648;Reactome: R-HSA-167242;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167243;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167158	"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex"
XP_031624251.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031633847.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031623029.1	3	Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_031640093.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_031640662.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69091	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Polymerase switching"
XP_031639096.1	7	Reactome: R-HSA-1474151;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-6614	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate biosynthesis";"One carbon pool by folate";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis"
XP_031634908.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_031632189.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_031625726.1	10	Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41	"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis"
XP_031633622.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"Endogenous sterols";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_031626400.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031618783.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_031630096.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174184	"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_031622891.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_031629309.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031630040.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031638374.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_031627027.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031617033.1	5	KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_031623875.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_031622845.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_031638708.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031627532.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031635676.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031622406.1	12	KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"G alpha (q) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031632133.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031631447.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031640953.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638	"Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_031628618.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_031627153.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_031633296.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031630295.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031624571.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031619946.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031640484.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300	"Chaperone Mediated Autophagy";"Aggrephagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors"
XP_031617590.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_031626462.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Neddylation";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins"
XP_031623281.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912	"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_031617756.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_031631604.1	7	KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"ATP biosynthesis";"Cristae formation";"Mitochondrial protein import"
XP_031620243.1	11	Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-75955	"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation"
XP_031633538.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_031625875.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787	"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state"
XP_031622468.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_031620177.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_031617230.1	10	MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-7909;MetaCyc: PWY-5497	"Folate transformations II (plants)";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)"
XP_031630544.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031626951.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031631745.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_031619530.1	56	Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091	"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells"
XP_031627278.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031634988.1	15	Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-5637810;Reactome: R-HSA-9665245;Reactome: R-HSA-1236382;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-9652282;Reactome: R-HSA-9665250;Reactome: R-HSA-9665244;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-9665233;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986	"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to sapitinib";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2"
XP_031624876.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis"
XP_031620862.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Glycerophospholipid metabolism";"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_031624719.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_031639070.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_031624220.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031632191.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_031625403.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031629910.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031630911.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031636373.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031624920.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_031618063.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_031631687.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_031635855.1	7	Reactome: R-HSA-5578999;MetaCyc: PWY-7255;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Glutathione metabolism"
XP_031619732.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031630485.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031638735.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_031640612.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_031616919.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_031625578.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031628803.1	26	Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-933541	"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"TRAF6 mediated IRF7 activation"
XP_031633816.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_031629768.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031635235.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031636918.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031620936.1	4	KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerol degradation I";"Glycerolipid metabolism"
XP_031631738.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_031624584.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_031622391.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins"
XP_031629086.1	3	Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_031622550.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031633500.1	9	KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-7385;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I"
XP_031622397.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_031622443.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031629510.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_031624932.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_031635989.1	13	Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090	"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"NCAM1 interactions";"ECM proteoglycans";"Signaling by PDGF";"Integrin cell surface interactions";"Extracellular matrix organization";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures"
XP_031641036.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031630354.1	4	KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931	"Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis"
XP_031640785.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_031635988.1	13	Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157	"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"NCAM1 interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Signaling by PDGF";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions"
XP_031623406.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031620178.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_031632305.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"Macroautophagy";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_031638356.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_031623931.1	9	Reactome: R-HSA-9608290;Reactome: R-HSA-9630222;Reactome: R-HSA-110331;Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9608287;Reactome: R-HSA-110330	"Defective MUTYH substrate processing";"Defective NTHL1 substrate binding";"Cleavage of the damaged purine";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_031623280.1	4	KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912	"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_031632391.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031630246.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745	"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_031625936.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670	"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway"
XP_031641216.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_031633438.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031626391.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_031620103.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031623301.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_031636279.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-114508	"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis"
XP_031626989.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685938	"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)"
XP_031624608.1	3	KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685	"Purine metabolism";"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species"
XP_031620104.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_031639520.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031628313.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031631677.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031617440.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031616857.1	19	Reactome: R-HSA-3000484;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Scavenging by Class F Receptors";"Scavenging by Class H Receptors";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Chylomicron remodeling";"LDL remodeling";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"LDL clearance";"Scavenging by Class B Receptors";"VLDL clearance";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"VLDL assembly"
XP_031624917.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031640791.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031640086.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031622402.1	12	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"DCC mediated attractive signaling";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"G alpha (q) signalling events";"mTOR signaling pathway"
XP_031636140.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031626029.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031631470.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031624285.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031624179.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_031633250.1	4	KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26	"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_031620184.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_031620483.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_031626601.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_031620561.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_031625528.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031619618.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031631495.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031635085.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_031622643.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_031620146.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_031631077.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031627234.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031638488.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_031623066.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031620370.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_031624554.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"Peptide chain elongation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_031637238.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031622508.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031626672.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031637951.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031620129.1	4	Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260	"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_031630719.1	7	Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-5578749	"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs"
XP_031621997.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364	"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_031631925.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552	"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Signaling by Leptin"
XP_031622570.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031624409.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_031630445.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_031627384.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_031636912.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031633608.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031632994.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs"
XP_031618805.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_031638741.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031627409.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031625225.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031640296.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031634096.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031630188.1	10	MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-6842	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II"
XP_031624921.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031631471.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031636766.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031619072.1	8	MetaCyc: PWY-6556;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;MetaCyc: PWY-7193	"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I"
XP_031624853.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031631427.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_031637329.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031627779.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_031638306.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031632594.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_031632899.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031630352.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_031634250.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031621992.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_031639729.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031625506.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-349425	"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_031626747.1	9	KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323	"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol"
XP_031628951.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_031639349.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_031616507.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031639508.1	6	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-389661	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Glyoxylate metabolism and glycine degradation"
XP_031630846.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031625801.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_031638344.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031629277.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031623243.1	30	Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-2122947;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-69231;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-2644607;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-1170546;Reactome: R-HSA-8939902;Reactome: R-HSA-2644606	"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"Iron uptake and transport";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Prolactin receptor signaling";"Regulation of RUNX2 expression and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_031624437.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_031630903.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_031625007.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_031633000.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_031620056.1	12	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-193692	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Regulated proteolysis of p75NTR"
XP_031636145.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031638355.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_031620626.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031637315.1	18	MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7115	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_031628085.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031635244.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031624906.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_031628499.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_031640053.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_031623192.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031619344.1	17	Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-8951664;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176407	"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Neddylation";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_031640396.1	14	MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4	"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism"
XP_031625061.1	11	KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-210455	"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle I";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism"
XP_031626651.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031632973.1	33	Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-3232142	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins"
XP_031632378.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031616804.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031631714.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031616741.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031640949.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031626793.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031625104.1	4	MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism"
XP_031630639.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031638140.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_031635197.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_031619679.1	3	KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_031641085.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
XP_031629317.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031636736.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_031632773.1	6	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-389661	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Glyoxylate metabolism and glycine degradation"
XP_031626444.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_031640380.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031618195.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031625386.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_031633461.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031640361.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_031635018.1	6	KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-5514;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I"
XP_031627115.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_031631853.1	6	MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)"
XP_031636501.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031621678.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031628958.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-380284;Reactome: R-HSA-2500257;Reactome: R-HSA-8854518;Reactome: R-HSA-9648025;Reactome: R-HSA-2565942;Reactome: R-HSA-68877;Reactome: R-HSA-5620912;Reactome: R-HSA-428890	"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Loss of proteins required for interphase microtubule organization from the centrosome";"Resolution of Sister Chromatid Cohesion";"AURKA Activation by TPX2";"EML4 and NUDC in mitotic spindle formation";"Regulation of PLK1 Activity at G2/M Transition";"Mitotic Prometaphase";"Anchoring of the basal body to the plasma membrane";"Role of ABL in ROBO-SLIT signaling"
XP_031633727.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859	"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly"
XP_031629898.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_031635475.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_031638823.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_031629083.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031640601.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031623300.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031624894.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_031633481.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031633114.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031629175.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_031617820.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_031626797.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_031628682.1	5	KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_031630176.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_031624768.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031627362.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031636270.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_031626422.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031623061.1	30	Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-1170546;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-69231;Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-202424	"Degradation of GLI2 by the proteasome";"Neddylation";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Cyclin D associated events in G1";"Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Downstream TCR signaling"
XP_031631442.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031637401.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_031636330.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_031638251.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031626637.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_031630270.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_031627883.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031630749.1	4	KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_031616397.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031641250.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031620900.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state"
XP_031631348.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031625289.1	7	MetaCyc: PWY-6277;MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_031628271.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031622258.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031637645.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_031623207.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_031618443.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_031628998.1	8	Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031634033.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031628483.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031638239.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_031634484.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-5610787	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state"
XP_031641284.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031623305.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031630152.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031638651.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_031632574.1	6	Reactome: R-HSA-389661;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"Glyoxylate metabolism and glycine degradation";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_031629451.1	3	KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle"
XP_031640893.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_031617188.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031625505.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031620290.1	4	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_031620458.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031620213.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031621494.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_031638464.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_031630385.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031625399.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031633477.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_031621149.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031640897.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_031632134.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031629231.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031624937.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_031623381.1	1	Reactome: R-HSA-419771	"Opsins"
XP_031630379.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031633782.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_031618592.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_031638432.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_031633043.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031633210.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_031629365.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_031638414.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031623882.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031619892.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_031627572.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_031640509.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031632990.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_031640512.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031633321.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-203927	"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis"
XP_031627536.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_031620641.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_031624618.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_031631203.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_031625688.1	12	KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;MetaCyc: PWY-5278	"Sulfur metabolism";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Sulfur metabolism";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Purine metabolism";"Selenate reduction";"Sulfite oxidation III"
XP_031637697.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_031621199.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031637516.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_031623261.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation"
XP_031632680.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-7901;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601	"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan"
XP_031629358.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_031621496.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_031634017.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031623960.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_031629720.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_031636665.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_031637784.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031640678.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031637431.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031626716.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_031635129.1	4	Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781	"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis"
XP_031640990.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_031639461.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_031635954.1	12	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition"
XP_031637736.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism"
XP_031625950.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724	"Macroautophagy";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription"
XP_031628114.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68962	"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex"
XP_031621808.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031628102.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031629549.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-735;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Fatty acid degradation"
XP_031634570.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031620472.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_031635021.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism"
XP_031619186.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_031617298.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031624221.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031637285.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_031639770.1	4	MetaCyc: PWY-7807;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Glyphosate degradation III";"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_031625277.1	3	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_031624866.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_031630717.1	7	Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-168333	"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_031625230.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031619292.1	20	KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-165159;KEGG: 04714+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400	"Human cytomegalovirus infection";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"mTOR signalling";"Thermogenesis";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"Relaxin signaling pathway";"Amino acids regulate mTORC1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_031629997.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_031639524.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031630181.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_031632629.1	11	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"HATs acetylate histones";"Ub-specific processing proteases";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_031633197.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031638378.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031641026.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031638852.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_031639431.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6969	"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_031639202.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_031628694.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031623687.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_031620150.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_031625932.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism"
XP_031631065.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031640091.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_031636669.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_031623711.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031617361.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway"
XP_031620519.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_031632084.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031634095.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031623282.1	4	KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912	"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_031631525.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031640080.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_031616972.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031639071.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_031619678.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031626417.1	20	Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint"
XP_031623338.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031616587.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_031619659.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_031616426.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_031637732.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031627568.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_031628130.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_031629894.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690	"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events"
XP_031618241.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031635096.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031628912.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031628523.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_031631332.1	52	Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-76061;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-73980;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-73780;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-5250924;Reactome: R-HSA-8851708;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-9018519	"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Termination";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Chain Elongation";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression"
XP_031632325.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_031632137.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031624561.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031622856.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_031620409.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031620901.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884	"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX"
XP_031638266.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031634155.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031641027.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031637418.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031626220.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031640247.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_031623515.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031638976.1	24	Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;Reactome: R-HSA-392451;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-2871837;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-165158;Reactome: R-HSA-202424;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920	"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"FCERI mediated NF-kB activation";"Thermogenesis";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"PI3K-Akt signaling pathway";"RSK activation";"Activation of AKT2";"Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability"
XP_031634069.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_031629306.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031621495.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_031626621.1	11	MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7782	"Anandamide biosynthesis I";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis"
XP_031633598.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031637928.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031617075.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031631391.1	8	KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268	"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Propanoate metabolism";"Pyruvate metabolism"
XP_031629893.1	10	Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10	"PPARA activates gene expression";"Butanoate metabolism";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies"
XP_031619695.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031626158.1	5	Reactome: R-HSA-9033241;Reactome: R-HSA-75896;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500	"Peroxisomal protein import";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins"
XP_031626791.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
XP_031636256.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
XP_031634350.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031618504.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031618135.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031640506.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_031625015.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_031617066.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_031619850.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031637564.1	17	Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-74259;MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6627;MetaCyc: PWY-6608;MetaCyc: PWY-5532;MetaCyc: PWY-7179-1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609	"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Purine catabolism";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Purine salvage";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Adenine and adenosine salvage III"
XP_031630036.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031640571.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_031626763.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031636722.1	9	Reactome: R-HSA-3371599;Reactome: R-HSA-70263;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086	"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_031621454.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_031631193.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031638865.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031635403.1	25	Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-380270;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Cilium Assembly";"Gap junction assembly";"HCMV Early Events";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_031635945.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_031620022.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_031617226.1	5	KEGG: 00520+2.5.1.7;KEGG: 00550+2.5.1.7;MetaCyc: PWY-7953;MetaCyc: PWY-6386;MetaCyc: PWY-6387	"Amino sugar and nucleotide sugar metabolism";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)"
XP_031637220.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031638571.1	3	KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_031619639.1	18	Reactome: R-HSA-9616222;Reactome: R-HSA-8866911;Reactome: R-HSA-9617828;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-69563;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-187577;Reactome: R-HSA-2559586;Reactome: R-HSA-8941855;Reactome: R-HSA-6785807;Reactome: R-HSA-6804116;Reactome: R-HSA-69895;Reactome: R-HSA-2559582;Reactome: R-HSA-8852276;Reactome: R-HSA-69231;Reactome: R-HSA-8878166	"Transcriptional regulation of granulopoiesis";"TFAP2 (AP-2) family regulates transcription of cell cycle factors";"FOXO-mediated transcription of cell cycle genes";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"p53-Dependent G1 DNA Damage Response";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"SCF(Skp2)-mediated degradation of p27/p21";"DNA Damage/Telomere Stress Induced Senescence";"RUNX3 regulates CDKN1A transcription";"Interleukin-4 and Interleukin-13 signaling";"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest";"Transcriptional activation of cell cycle inhibitor p21";"Senescence-Associated Secretory Phenotype (SASP)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cyclin D associated events in G1";"Transcriptional regulation by RUNX2"
XP_031631000.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Nephrin family interactions";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_031624994.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031630859.1	6	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-389661;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate metabolism and glycine degradation";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression"
XP_031621573.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031639537.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031627894.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031637657.1	13	KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation"
XP_031626564.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_031640607.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_031632054.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031626950.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031619797.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_031639473.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"HSF1-dependent transactivation";"mTOR signalling";"mTORC1-mediated signalling"
XP_031617854.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_031628230.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031632479.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_031627208.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031624194.1	23	Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-202040	"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"G-protein activation"
XP_031623820.1	5	Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983	"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)"
XP_031619034.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031622912.1	12	MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_031620009.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031617877.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031622044.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031634798.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-75105	"Glyoxylate metabolism and glycine degradation";"Fatty acyl-CoA biosynthesis"
XP_031623201.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_031640826.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031638952.1	24	Reactome: R-HSA-6804757;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-114604;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-444257;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-165158;Reactome: R-HSA-202424;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764	"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"FCERI mediated NF-kB activation";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"GPVI-mediated activation cascade";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"RSK activation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Activation of AKT2";"Downstream TCR signaling";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling"
XP_031616712.1	7	KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-71064;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61	"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_031629370.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031632339.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031627843.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975;MetaCyc: PWY-7204	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_031640101.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031625901.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_031633478.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_031633103.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031626533.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031624200.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031633037.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_031628992.1	5	Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3"
XP_031618193.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031630556.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031627938.1	13	Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400	"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"mTOR signalling";"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_031641022.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031621290.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_031623017.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031624931.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_031630413.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_031635363.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031618111.1	16	Reactome: R-HSA-182218;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-190873;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-164939;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-8856825	"Nef Mediated CD8 Down-regulation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Gap junction degradation";"Recycling pathway of L1";"LDL clearance";"Nef mediated downregulation of CD28 cell surface expression";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis"
XP_031626556.1	5	MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_031629963.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_031631597.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031623737.1	6	Reactome: R-HSA-6785470;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion"
XP_031625339.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_031625455.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_031628386.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031627842.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_031632221.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_031631485.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296	"HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome"
XP_031641273.1	7	Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632684	"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state"
XP_031637847.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031620518.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_031631679.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031640514.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_031617384.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031630183.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031617114.1	5	MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)"
XP_031619700.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031621990.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex"
XP_031629106.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_031627534.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031621946.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_031636381.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031640385.1	14	MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_031626298.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_031622861.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031629691.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031621249.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_031635074.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031624198.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031623397.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_031622037.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031638738.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)"
XP_031630566.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_031626373.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031624366.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031626927.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031637430.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_031624621.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031627561.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031618911.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_031622539.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031632347.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031620077.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_031629766.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031628502.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_031626401.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031628029.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_031626490.1	5	MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560	"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II"
XP_031622598.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031620514.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_031619859.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation"
XP_031616832.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state"
XP_031638321.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031634828.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_031623590.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_031641146.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_031631737.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_031629329.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_031621443.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031630573.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031635490.1	57	Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling"
XP_031618233.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031640295.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031632088.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031618222.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031629337.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_031620212.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031620055.1	12	Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700	"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_031627629.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_031617826.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031620719.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_031622089.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110329	"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine"
XP_031631889.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031638467.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_031628942.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031622244.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031638316.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_031617369.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway"
XP_031630244.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation"
XP_031637953.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031623115.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031630053.1	13	Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-2022857;MetaCyc: PWY-6807;Reactome: R-HSA-4341670	"Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Glycosphingolipid metabolism";"Galactose metabolism";"Other glycan degradation";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"MPS IV - Morquio syndrome B";"Keratan sulfate degradation";"Xyloglucan degradation II (exoglucanase)";"Defective NEU1 causes sialidosis"
XP_031628903.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031637175.1	30	Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-2565942;Reactome: R-HSA-69231;Reactome: R-HSA-2644607;Reactome: R-HSA-8939902;Reactome: R-HSA-1170546;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-2644606;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783	"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of RUNX2 expression and activity";"Prolactin receptor signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"Neddylation";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome"
XP_031634159.1	9	KEGG: 00350+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5	"Tyrosine metabolism";"Tyrosine catabolism";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism"
XP_031617493.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031636376.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031622918.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031633508.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_031636308.1	3	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020	"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import"
XP_031628254.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;MetaCyc: PWY-7511	"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Protein ubiquitination"
XP_031630914.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031617572.1	8	Reactome: R-HSA-5173105;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921	"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)"
XP_031632070.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031620979.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_031629511.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760	"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation"
XP_031620162.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445	"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation"
XP_031623194.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_031628655.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_031629482.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_031630745.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_031637931.1	24	Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Aggrephagy";"HCMV Early Events";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_031636720.1	9	Reactome: R-HSA-70263;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142	"Gluconeogenesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_031633086.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_031617845.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031619739.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5789	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_031627000.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_031623485.1	31	MetaCyc: PWY-4381;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-7664;MetaCyc: PWYG-321;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-8049;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-5367;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-6113;MetaCyc: PWY-5994;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-6799;MetaCyc: PWY-6282;MetaCyc: PWY-7723;MetaCyc: PWY-5971	"Fatty acid biosynthesis initiation (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bacterial bioluminescence";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_031622576.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031632849.1	7	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-110362	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair"
XP_031623858.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031640533.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_031622147.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031640724.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031638244.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031627118.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031617876.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031620544.1	11	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-383280	"PPARA activates gene expression";"Generic Transcription Pathway";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway"
XP_031627413.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_031629147.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031616843.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031625933.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_031632291.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_031626555.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_031629733.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_031640799.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031618220.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031633617.1	5	Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-211981	"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Endogenous sterols";"Phase I - Functionalization of compounds";"Xenobiotics"
XP_031637927.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031616882.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031639545.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031635878.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031636282.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-5981	"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III"
XP_031625796.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_031619871.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_031618493.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031632712.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031617823.1	15	Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-416476	"Signaling by SCF-KIT";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"G alpha (q) signalling events"
XP_031635116.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_031623074.1	8	MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2	"ATP biosynthesis";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Photosynthesis";"Ion channel transport";"Oxidative phosphorylation"
XP_031617249.1	5	MetaCyc: PWY-7953;KEGG: 00520+1.3.1.98;MetaCyc: PWY-6387;KEGG: 00550+1.3.1.98;MetaCyc: PWY-6386	"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)"
XP_031626579.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031639814.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_031631361.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_031626748.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031634073.1	16	Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246	"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript"
XP_031617915.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031623414.1	7	KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_031630153.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031622476.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-203927	"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis"
XP_031622283.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_031640394.1	14	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_031639975.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031630264.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031623877.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_031623930.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-9630222;Reactome: R-HSA-9608290;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-110330;Reactome: R-HSA-9608287;Reactome: R-HSA-110329	"Cleavage of the damaged purine";"Defective NTHL1 substrate binding";"Defective MUTYH substrate processing";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate binding";"Cleavage of the damaged pyrimidine"
XP_031617907.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031640360.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_031637468.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031639896.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031617762.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031630347.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_031631748.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_031625942.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state"
XP_031620011.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031632262.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031622763.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_031638337.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_031634574.1	12	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-205043	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus"
XP_031635081.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_031631441.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760	"RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation"
XP_031624499.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031621548.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_031628750.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_031619870.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031626103.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_031630420.1	4	Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026	"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)"
XP_031635648.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031622350.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198	"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis"
XP_031621313.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_031627816.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_031638983.1	24	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-444257;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-165158;Reactome: R-HSA-202424;Reactome: R-HSA-5674400	"Human cytomegalovirus infection";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"RSK activation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Activation of AKT2";"Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_031633666.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_031626255.1	12	MetaCyc: PWY-7238;MetaCyc: PWY-3801;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343	"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Stachyose degradation";"Starch and sucrose metabolism";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I"
XP_031619642.1	18	Reactome: R-HSA-5674400;Reactome: R-HSA-69563;Reactome: R-HSA-6785807;Reactome: R-HSA-8941855;Reactome: R-HSA-2559586;Reactome: R-HSA-187577;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8866911;Reactome: R-HSA-9616222;Reactome: R-HSA-198323;Reactome: R-HSA-9617828;Reactome: R-HSA-2559582;Reactome: R-HSA-8852276;Reactome: R-HSA-69895;Reactome: R-HSA-8878166;Reactome: R-HSA-69231;Reactome: R-HSA-6804116	"Constitutive Signaling by AKT1 E17K in Cancer";"p53-Dependent G1 DNA Damage Response";"Interleukin-4 and Interleukin-13 signaling";"RUNX3 regulates CDKN1A transcription";"DNA Damage/Telomere Stress Induced Senescence";"SCF(Skp2)-mediated degradation of p27/p21";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"TFAP2 (AP-2) family regulates transcription of cell cycle factors";"Transcriptional regulation of granulopoiesis";"AKT phosphorylates targets in the cytosol";"FOXO-mediated transcription of cell cycle genes";"Senescence-Associated Secretory Phenotype (SASP)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Transcriptional activation of cell cycle inhibitor p21";"Transcriptional regulation by RUNX2";"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest"
XP_031636588.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031640613.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_031622609.1	2	KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26	"Starch and sucrose metabolism";"Galactose metabolism"
XP_031619694.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031625284.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_031633253.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031637696.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_031628814.1	13	Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1	"G alpha (12/13) signalling events";"Thermogenesis";"EPHA-mediated growth cone collapse";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"PI3K-Akt signaling pathway";"EPHB-mediated forward signaling";"mTOR signaling pathway"
XP_031625667.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN"
XP_031628414.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_031633093.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_031628422.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_031623958.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031626130.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031636892.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_031634805.1	5	Reactome: R-HSA-446199;Reactome: R-HSA-4755579;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048	"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Androgen biosynthesis"
XP_031640958.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031623003.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_031631603.1	13	Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52	"CS/DS degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis"
XP_031636788.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031631929.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-1170546	"Signaling by Leptin";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling"
XP_031628952.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_031634618.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031638816.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_031628182.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_031634843.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events"
XP_031637642.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031623324.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031632645.1	6	MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-4381	"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_031633505.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_031616343.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_031633615.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211981	"Endogenous sterols";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Xenobiotics"
XP_031633497.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_031617457.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031638225.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_031633104.1	4	MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8040	"Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis"
XP_031617340.1	7	KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;Reactome: R-HSA-6782315;MetaCyc: PWY-5188;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism"
XP_031623148.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031620788.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031625723.1	4	Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_031622021.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_031640751.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_031624186.1	14	Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-5497;Reactome: R-HSA-8851680;KEGG: 00983+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-6999;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-6607;MetaCyc: PWY-5695;KEGG: 00232+1.17.3.2	"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Theophylline degradation";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Caffeine metabolism"
XP_031632698.1	4	MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59	"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism"
XP_031635913.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_031626599.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_031616649.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_031635400.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031626331.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_031620838.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031624138.1	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
XP_031631003.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"NCAM signaling for neurite out-growth"
XP_031622538.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031627272.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_031627715.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_031625185.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_031630162.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_031619730.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031620728.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031628052.1	6	Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168	"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_031618910.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_031624207.1	6	MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;Reactome: R-HSA-74259	"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism"
XP_031627794.1	52	Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-202424	"Hedgehog ligand biogenesis";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling"
XP_031628775.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_031616373.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031633619.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211976	"Xenobiotics";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Endogenous sterols"
XP_031627952.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_031618641.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031619271.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_031640627.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031623244.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031628365.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031621080.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_031622903.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_031635146.1	4	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_031618646.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031628092.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_031633596.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_031627569.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_031625024.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_031619645.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_031623786.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_031625807.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-141444	"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_031630958.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031628534.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_031631552.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031620208.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031625856.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_031626877.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031623198.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_031627798.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031619879.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031637506.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_031640387.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053	"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II"
XP_031629741.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031631742.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031624795.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_031629685.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031628336.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031638107.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031618686.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_031632352.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031633141.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_031620931.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_031617125.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031618464.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_031621526.1	30	Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-2564830;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-75953	"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Cytosolic iron-sulfur cluster assembly";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation"
XP_031624785.1	18	KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7115	"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_031633329.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_031640083.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_031618470.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_031624628.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031641020.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167290	"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation"
XP_031623624.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031638520.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031625999.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_031618601.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031628572.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031626616.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_031635491.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785	"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Neddylation";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome"
XP_031618072.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031631486.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_031630990.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-7736;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7102;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-7721	"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis"
XP_031640248.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_031635931.1	6	MetaCyc: PWY-6907;MetaCyc: PWY-7356;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;Reactome: R-HSA-196819	"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism"
XP_031624053.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031634128.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_031640487.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031623677.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031626734.1	11	Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_031625530.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
XP_031620440.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_031637441.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031620539.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031618383.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031617733.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_031619965.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_031619277.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_031621823.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_031634508.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_031626464.1	5	Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012	"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_031626664.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031626941.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031630616.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_031627038.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_031627996.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_031640045.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_031633118.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031617106.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_031637225.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_031636233.1	4	Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_031622952.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031631443.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_031626926.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031620635.1	5	KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_031637588.1	1	Reactome: R-HSA-6803529	"FGFR2 alternative splicing"
XP_031632709.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560	"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism"
XP_031619441.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_031621427.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031629429.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_031626524.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031633108.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_031637740.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_031627436.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_031630922.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031633780.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase"
XP_031637015.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953	"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation"
XP_031626744.1	9	KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_031639555.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7117	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_031630250.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_031619662.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_031629184.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_031629122.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11	"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_031618853.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750	"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6"
XP_031641282.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_031629379.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_031617186.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_031630313.1	8	Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Signaling by Hippo";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_031621263.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031629486.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_031621690.1	6	Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism"
XP_031621538.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031639799.1	34	Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-165054	"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA"
XP_031626192.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
XP_031624791.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031626726.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_031638247.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031640693.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_031624443.1	7	Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_031616730.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031619091.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031622567.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031623703.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031637221.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031619617.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031633390.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_031621681.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7602	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_031639451.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031630581.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_031618243.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031623957.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031633459.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_031619108.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031623866.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_031636987.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400	"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_031616840.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031633857.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399	"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Aggrephagy"
XP_031636208.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-7285;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-7286;MetaCyc: PWY-6829	"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)"
XP_031640033.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_031632874.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_031636888.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031620968.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_031620054.1	12	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-193692	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Regulated proteolysis of p75NTR"
XP_031629827.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128	"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling"
XP_031616372.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031635128.1	4	Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781	"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis"
XP_031639944.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_031618607.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031635009.1	30	Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-1170546;Reactome: R-HSA-2644606;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942	"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Neddylation";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition"
XP_031640576.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031625228.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031627557.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_031618203.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031636779.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031638339.1	7	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-110362	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair"
XP_031639544.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031626021.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031622852.1	10	MetaCyc: PWY-4661;MetaCyc: PWY-6362;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol"
XP_031618706.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_031617944.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_031640206.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_031635293.1	5	Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_031640786.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols"
XP_031634178.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_031631755.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_031639704.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72163	"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway"
XP_031633654.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_031632469.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031627575.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_031631027.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031618213.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031627686.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031637510.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_031630069.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_031621200.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031632058.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031638588.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031620854.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_031626507.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_031628529.1	18	Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4	"Acyl chain remodelling of PE";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism"
XP_031636271.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_031639402.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_031635677.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_031627282.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031627844.1	4	MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_031634048.1	18	Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4	"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Ether lipid metabolism"
XP_031625299.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031618131.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_031621444.1	8	Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Activation of RAC1";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_031626340.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-5658442	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"Regulation of RAS by GAPs"
XP_031623095.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031638359.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031623015.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031638818.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_031637372.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031629463.1	3	Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_031639998.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031628470.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_031622450.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_031638726.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_031628113.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_031627447.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_031632530.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_031623220.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_031641079.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174184	"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_031640806.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031622919.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_031632467.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031618211.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031640081.1	3	Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_031637218.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031633971.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031627994.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_031626393.1	14	Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135	"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Dual incision in TC-NER"
XP_031617168.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657	"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes"
XP_031624922.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031617314.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_031616748.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031627630.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_031633009.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_031620482.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_031631759.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031629259.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_031627909.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_031623518.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031634815.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_031617037.1	15	Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Regulation of MECP2 expression and activity"
XP_031631291.1	3	MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695	"Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation"
XP_031635354.1	13	MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_031635318.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_031628802.1	26	Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-2122947;Reactome: R-HSA-933541	"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation"
XP_031625516.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_031622528.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031630154.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_031627543.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692	"Ion transport by P-type ATPases";"Ion homeostasis";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity"
XP_031640234.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-7285;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_031622471.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_031627425.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_031640266.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_031622020.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_031634550.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031616425.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-983168	"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031635667.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_031627562.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749	"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs"
XP_031635423.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_031627967.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_031620729.1	4	Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664	"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation"
XP_031628061.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-141430	"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_031637522.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_031634200.1	179	Reactome: R-HSA-6804760;Reactome: R-HSA-450302;Reactome: R-HSA-532668;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-2408557;Reactome: R-HSA-8856825;Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-209560;Reactome: R-HSA-983168;Reactome: R-HSA-9013507;Reactome: R-HSA-69231;Reactome: R-HSA-6804757;Reactome: R-HSA-6804756;Reactome: R-HSA-2565942;Reactome: R-HSA-209543;Reactome: R-HSA-3769402;Reactome: R-HSA-2559582;Reactome: R-HSA-5656169;Reactome: R-HSA-9615710;Reactome: R-HSA-174178;Reactome: R-HSA-2173796;Reactome: R-HSA-5693607;Reactome: R-HSA-69017;Reactome: R-HSA-72689;Reactome: R-HSA-5689603;Reactome: R-HSA-5696397;Reactome: R-HSA-5668541;Reactome: R-HSA-8951664;Reactome: R-HSA-174490;Reactome: R-HSA-1236974;Reactome: R-HSA-3134975;Reactome: R-HSA-901032;Reactome: R-HSA-72764;Reactome: R-HSA-168928;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-156827;Reactome: R-HSA-211733;Reactome: R-HSA-937042;Reactome: R-HSA-975163;Reactome: R-HSA-2559580;Reactome: R-HSA-936440;Reactome: R-HSA-5689877;Reactome: R-HSA-4608870;Reactome: R-HSA-450321;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-9033241;Reactome: R-HSA-5610780;Reactome: R-HSA-6781827;Reactome: R-HSA-3785653;Reactome: R-HSA-174048;Reactome: R-HSA-8939902;Reactome: R-HSA-168638;Reactome: R-HSA-174184;Reactome: R-HSA-936964;Reactome: R-HSA-9636383;Reactome: R-HSA-69601;Reactome: R-HSA-168927;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-6782210;Reactome: R-HSA-5357956;Reactome: R-HSA-174084;Reactome: R-HSA-9013973;Reactome: R-HSA-2173795;Reactome: R-HSA-156902;Reactome: R-HSA-5607764;Reactome: R-HSA-6807004;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9646399;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-1295596;Reactome: R-HSA-205043;Reactome: R-HSA-5655862;Reactome: R-HSA-5689901;Reactome: R-HSA-69481;Reactome: R-HSA-175474;Reactome: R-HSA-9604323;Reactome: R-HSA-9645460;Reactome: R-HSA-5654726;Reactome: R-HSA-180585;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-2691232;Reactome: R-HSA-977225;Reactome: R-HSA-8866652;Reactome: R-HSA-5358346;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-4641257;Reactome: R-HSA-162588;Reactome: R-HSA-110312;Reactome: R-HSA-2644606;Reactome: R-HSA-975110;Reactome: R-HSA-2122948;Reactome: R-HSA-9637628;Reactome: R-HSA-5675221;Reactome: R-HSA-5205685;Reactome: R-HSA-937039;Reactome: R-HSA-5362768;Reactome: R-HSA-8875360;Reactome: R-HSA-937041;Reactome: R-HSA-8849469;Reactome: R-HSA-2173788;Reactome: R-HSA-9014325;Reactome: R-HSA-5696395;Reactome: R-HSA-9020702;Reactome: R-HSA-5685942;Reactome: R-HSA-192823;Reactome: R-HSA-2173791;Reactome: R-HSA-1169091;Reactome: R-HSA-912631;Reactome: R-HSA-1253288;Reactome: R-HSA-5357905;Reactome: R-HSA-5654727;Reactome: R-HSA-5654733;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-1358803;Reactome: R-HSA-8866654;Reactome: R-HSA-5607761;Reactome: R-HSA-179409;Reactome: R-HSA-1236382;Reactome: R-HSA-450408;Reactome: R-HSA-6782135;Reactome: R-HSA-9613829;Reactome: R-HSA-2672351;Reactome: R-HSA-6781823;Reactome: R-HSA-975957;Reactome: R-HSA-8852276;Reactome: R-HSA-182971;Reactome: R-HSA-917729;Reactome: R-HSA-69541;Reactome: R-HSA-8863795;Reactome: R-HSA-2122947;Reactome: R-HSA-4641263;Reactome: R-HSA-2559585;Reactome: R-HSA-349425;Reactome: R-HSA-3322077;Reactome: R-HSA-975144;Reactome: R-HSA-2979096;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-937072;Reactome: R-HSA-6791226;Reactome: R-HSA-5696394;Reactome: R-HSA-180534;Reactome: R-HSA-110320;Reactome: R-HSA-5675482;Reactome: R-HSA-445989;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-2894862;Reactome: R-HSA-5693565;Reactome: R-HSA-187577;Reactome: R-HSA-5656121;Reactome: R-HSA-5678895;Reactome: R-HSA-5696400;Reactome: R-HSA-1169408;Reactome: R-HSA-8876493;Reactome: R-HSA-8948747;Reactome: R-HSA-400253;Reactome: R-HSA-1799339;Reactome: R-HSA-5654732;Reactome: R-HSA-8856828;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-975956;Reactome: R-HSA-5687128;Reactome: R-HSA-72706	"Regulation of TP53 Activity through Methylation";"activated TAK1 mediates p38 MAPK activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Selenocysteine synthesis";"Cargo recognition for clathrin-mediated endocytosis";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"NF-kB is activated and signals survival";"Antigen processing: Ubiquitination & Proteasome degradation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Cyclin D associated events in G1";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PLK1 Activity at G2/M Transition";"p75NTR recruits signalling complexes";"Deactivation of the beta-catenin transactivating complex";"Senescence-Associated Secretory Phenotype (SASP)";"Termination of translesion DNA synthesis";"Late endosomal microautophagy";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Processing of DNA double-strand break ends";"CDK-mediated phosphorylation and removal of Cdc6";"Formation of a pool of free 40S subunits";"UCH proteinases";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TNFR2 non-canonical NF-kB pathway";"Neddylation";"Membrane binding and targetting of GAG proteins";"ER-Phagosome pathway";"Regulation of innate immune responses to cytosolic DNA";"ER Quality Control Compartment (ERQC)";"Eukaryotic Translation Termination";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"IRAK2 mediated activation of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Oxidative Stress Induced Senescence";"Negative regulators of DDX58/IFIH1 signaling";"Josephin domain DUBs";"Asymmetric localization of PCP proteins";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Peroxisomal protein import";"Degradation of GLI1 by the proteasome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Myoclonic epilepsy of Lafora";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of RUNX2 expression and activity";"NOD1/2 Signaling Pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Prevention of phagosomal-lysosomal fusion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TICAM1, RIP1-mediated IKK complex recruitment";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TNFR1-induced NFkappaB signaling pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"TICAM1-dependent activation of IRF3/IRF7";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Peptide chain elongation";"CLEC7A (Dectin-1) signaling";"Negative regulation of MET activity";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Aggrephagy";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Spry regulation of FGF signaling";"NRIF signals cell death from the nucleus";"Translesion synthesis by POLK";"Metalloprotease DUBs";"G2/M Checkpoints";"Assembly Of The HIV Virion";"Negative regulation of NOTCH4 signaling";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of FGFR1 signaling";"Vif-mediated degradation of APOBEC3G";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Amyloid fiber formation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Hedgehog ligand biogenesis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Degradation of AXIN";"Budding and maturation of HIV virion";"Translesion synthesis by REV1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Modulation by Mtb of host immune system";"Negative regulation of MAPK pathway";"Pink/Parkin Mediated Mitophagy";"IRAK1 recruits IKK complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"InlB-mediated entry of Listeria monocytogenes into host cell";"IKK complex recruitment mediated by RIP1";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Downregulation of TGF-beta receptor signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Formation of Incision Complex in GG-NER";"Interleukin-1 signaling";"HDR through Homologous Recombination (HRR)";"Viral mRNA Translation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Activation of NF-kappaB in B cells";"Regulation of signaling by CBL";"Downregulation of ERBB4 signaling";"Regulation of TNFR1 signaling";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR4 signaling";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downregulation of ERBB2:ERBB3 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"APC-Cdc20 mediated degradation of Nek2A";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dual incision in TC-NER";"Chaperone Mediated Autophagy";"Stimuli-sensing channels";"Formation of TC-NER Pre-Incision Complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Stabilization of p53";"Downregulation of ERBB2 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of FZD by ubiquitination";"Oncogene Induced Senescence";"Autodegradation of the E3 ubiquitin ligase COP1";"Glycogen synthesis";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"DNA Damage Recognition in GG-NER";"Vpu mediated degradation of CD4";"Translesion Synthesis by POLH";"Regulation of necroptotic cell death";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SCF(Skp2)-mediated degradation of p27/p21";"Translesion synthesis by POLI";"Defective CFTR causes cystic fibrosis";"Dual Incision in GG-NER";"ISG15 antiviral mechanism";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of PTEN localization";"Circadian Clock";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of FGFR3 signaling";"Clathrin-mediated endocytosis";"Hedgehog 'on' state";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"MAPK6/MAPK4 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_031616693.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031620398.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031624177.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_031629909.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031630161.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031636576.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031633822.1	10	Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-382556;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"Recycling of eIF2:GDP";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ABC-family proteins mediated transport";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_031623573.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_031640633.1	40	Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-5617472;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-113418	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex"
XP_031637428.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_031622512.1	3	MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_031628494.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_031640721.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031621213.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-1236974	"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway"
XP_031624137.1	3	Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859	"Protein methylation";"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_031623784.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_031633506.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_031635893.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295	"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation"
XP_031640614.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_031629695.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031632425.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031638827.1	7	KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-7039	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_031625291.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_031621236.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031616399.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031623994.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031618431.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031617385.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031617050.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_031621271.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_031631644.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031618136.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_031620592.1	10	MetaCyc: PWY-7849;Reactome: R-HSA-3000171;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-2453902;Reactome: R-HSA-977225	"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Neutrophil degranulation";"Retinoid cycle disease events";"Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation"
XP_031629119.1	5	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_031630905.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031625732.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031635790.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031622217.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031627187.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031634834.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_031627344.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_031628636.1	5	MetaCyc: PWY-6387;KEGG: 00550+6.3.2.4;MetaCyc: PWY-6386;MetaCyc: PWY-7953;KEGG: 00473+6.3.2.4	"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"D-Alanine metabolism"
XP_031619932.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_031625025.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)"
XP_031622317.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031640100.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-3371453	"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response"
XP_031628380.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031621248.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_031632999.1	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_031631071.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031619688.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031637949.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031626798.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_031621155.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_031618198.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031629818.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_031623098.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031616586.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_031619332.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_031640379.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031621289.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_031631329.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)"
XP_031617699.1	13	KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation"
XP_031626506.1	14	MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs"
XP_031621483.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031634101.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031633132.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-113418	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex"
XP_031617275.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_031625934.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555	"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events"
XP_031623628.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_031632175.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_031621677.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031637222.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_031635646.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922	"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis"
XP_031617852.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_031620455.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031627364.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_031624933.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_031619238.1	14	KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-975634;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4	"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism"
XP_031618291.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031640386.1	14	MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_031640098.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159236	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031632358.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_031633306.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_031638648.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_031634483.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_031631704.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031624515.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_031637491.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031635662.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_031624127.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031631035.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031626602.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_031627276.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031623318.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_031627643.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031634295.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031629672.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_031627424.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_031621740.1	9	Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-113507	"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"E2F-enabled inhibition of pre-replication complex formation"
XP_031621320.1	11	Reactome: R-HSA-1989781;MetaCyc: PWY-7938;KEGG: 00906+2.5.1.32+5.5.1.19;MetaCyc: PWY-5943;MetaCyc: PWY-7947;MetaCyc: PWY-7939;MetaCyc: PWY-7591;MetaCyc: PWY-6279;MetaCyc: PWY-5947;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"PPARA activates gene expression";"Isorenieratene biosynthesis I (actinobacteria)";"Carotenoid biosynthesis";"Beta-carotene biosynthesis";"Flexixanthin biosynthesis";"Chlorobactene biosynthesis";"Okenone biosynthesis";"Myxol-2' fucoside biosynthesis";"Lutein biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_031638415.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031627533.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031638947.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031635772.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031627024.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031618459.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031640160.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_031617485.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031636277.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-422356	"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion"
XP_031628759.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_031629763.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031625390.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_031639388.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_031618503.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031631064.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031628815.1	12	Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9609736	"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors"
XP_031629257.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_031632281.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031625897.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031622871.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594	"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events"
XP_031634613.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031618612.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031638935.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_031632478.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_031627082.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031616841.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031626099.1	19	Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026	"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"LDL remodeling";"Chylomicron remodeling";"Scavenging by Class F Receptors";"Scavenging by Class H Receptors";"Chylomicron clearance"
XP_031633578.1	14	Reactome: R-HSA-6798695;Reactome: R-HSA-1474228;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985	"Neutrophil degranulation";"Degradation of the extracellular matrix";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4"
XP_031626032.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031634195.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_031624368.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_031622381.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_031617501.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_031633512.1	22	Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000	"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation"
XP_031635814.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031629551.1	20	KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-7338	"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Peroxisomal protein import";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_031637489.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031621253.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_031641004.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_031631076.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031635002.1	15	Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-9665244;Reactome: R-HSA-9665250;Reactome: R-HSA-1227986;Reactome: R-HSA-9665247;Reactome: R-HSA-9665233;Reactome: R-HSA-9665246;Reactome: R-HSA-9665249;Reactome: R-HSA-9652282;Reactome: R-HSA-9665245;Reactome: R-HSA-9665251;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285;Reactome: R-HSA-5637810	"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to afatinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by EGFRvIII"
XP_031635707.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031630578.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_031635325.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_031638977.1	18	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation"
XP_031625280.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_031622370.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_031628825.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244	"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Long-term potentiation"
XP_031633157.1	18	Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4	"Acyl chain remodelling of PE";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"alpha-Linolenic acid metabolism"
XP_031638843.1	4	Reactome: R-HSA-3371453;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation";"Mitochondrial protein import"
XP_031618352.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_031617042.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031630804.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031619342.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_031619899.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031617243.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_031627554.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_031620057.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_031622515.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_031637749.1	16	MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5749;KEGG: 00020+6.2.1.4;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Methylaspartate cycle";"Itaconate degradation";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes"
XP_031617235.1	1	Reactome: R-HSA-2022923	"Dermatan sulfate biosynthesis"
XP_031639579.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031628159.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_031621281.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031634553.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031639302.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031619889.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_031629203.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031638673.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_031631900.1	5	MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7919	"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)"
XP_031624935.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_031627235.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031627169.1	8	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031617450.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_031616619.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_031634857.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031628772.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_031623005.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031626633.1	5	MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism"
XP_031623914.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031629105.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_031621146.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_031623890.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031622999.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_031632968.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031627616.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-141444	"MHC class II antigen presentation";"Separation of Sister Chromatids";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_031628966.1	14	Reactome: R-HSA-428890;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-68877;Reactome: R-HSA-8854518;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-141444;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5663220	"Role of ABL in ROBO-SLIT signaling";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Mitotic Prometaphase";"AURKA Activation by TPX2";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins"
XP_031637291.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031619640.1	18	Reactome: R-HSA-8878166;Reactome: R-HSA-69231;Reactome: R-HSA-8852276;Reactome: R-HSA-2559582;Reactome: R-HSA-69895;Reactome: R-HSA-6804116;Reactome: R-HSA-6785807;Reactome: R-HSA-8941855;Reactome: R-HSA-2559586;Reactome: R-HSA-187577;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-5674400;Reactome: R-HSA-69563;Reactome: R-HSA-198323;Reactome: R-HSA-9617828;Reactome: R-HSA-8866911;Reactome: R-HSA-9616222	"Transcriptional regulation by RUNX2";"Cyclin D associated events in G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional activation of cell cycle inhibitor p21";"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest";"Interleukin-4 and Interleukin-13 signaling";"RUNX3 regulates CDKN1A transcription";"DNA Damage/Telomere Stress Induced Senescence";"SCF(Skp2)-mediated degradation of p27/p21";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Constitutive Signaling by AKT1 E17K in Cancer";"p53-Dependent G1 DNA Damage Response";"AKT phosphorylates targets in the cytosol";"FOXO-mediated transcription of cell cycle genes";"TFAP2 (AP-2) family regulates transcription of cell cycle factors";"Transcriptional regulation of granulopoiesis"
XP_031633434.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_031631751.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_031632681.1	12	MetaCyc: PWY-801;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-6936;MetaCyc: PWY-6842;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187	"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Glutathione-mediated detoxification II";"Tryptophan catabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine"
XP_031623651.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031636773.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031631001.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Neutrophil degranulation"
XP_031621385.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_031632376.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031617039.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_031639482.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_031641017.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031631584.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031633514.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337	"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding"
XP_031627055.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_031641227.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation"
XP_031625064.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_031632488.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_031641168.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism"
XP_031618813.1	6	KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;Reactome: R-HSA-913709	"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins"
XP_031626551.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_031618689.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_031625800.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168325	"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis"
XP_031637313.1	18	MetaCyc: PWY-7115;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis"
XP_031618888.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_031638646.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031628366.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031639899.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031626023.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_031639629.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031626359.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031621696.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_031618933.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031627251.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031636324.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_031617916.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031629450.1	3	MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K"
XP_031628773.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_031622666.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_031634698.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6804115	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_031631863.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031632641.1	6	MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-4381	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_031617821.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_031633531.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592	"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1"
XP_031625333.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism"
XP_031628367.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_031631334.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_031639932.1	7	MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11	"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_031617754.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_031621876.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_031621874.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_031624550.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_031629801.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031631058.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031619827.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase"
XP_031620210.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031636558.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_031639576.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031629681.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_031633725.1	42	KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6944;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-6863;MetaCyc: PWY-5138;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7007;MetaCyc: PWY-6883;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00410+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7094;MetaCyc: PWY-7401;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-6435;MetaCyc: PWY-7778;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5789;MetaCyc: PWY-5136;MetaCyc: PWY-7654	"Caprolactam degradation";"Spodoptera littoralis pheromone biosynthesis";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Androstenedione degradation";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol I";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid elongation";"Tryptophan metabolism";"Fatty acid degradation";"Phenylalanine metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Valine, leucine and isoleucine degradation";"Limonene and pinene degradation";"Fermentation to 2-methylbutanoate";"Lysine degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"beta-Alanine metabolism";"Geraniol degradation";"Carbon fixation pathways in prokaryotes";"Glutaryl-coa degradation";"Fatty acid salvage";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"Fatty acid degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"4-hydroxybenzoate biosynthesis III (plants)";"2-methylpropene degradation";"Toluene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Aminobenzoate degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation II (plant peroxisome)";"(8E,10E)-dodeca-8,10-dienol biosynthesis"
XP_031619393.1	7	MetaCyc: PWY-5265;MetaCyc: PWY-6471;Reactome: R-HSA-5633231;MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-6385;KEGG: 00550+2.4.1.227	"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis"
XP_031625825.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_031622879.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031623396.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_031632163.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_031628172.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_031617655.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628	"O-linked glycosylation";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_031617816.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_031623918.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_031640772.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031641083.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_031626149.1	5	Reactome: R-HSA-75896;MetaCyc: PWY-7782;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins"
XP_031617491.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031623568.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_031624638.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031636909.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031638176.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031621497.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_031622531.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031623644.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031618199.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031627623.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_031633860.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031631201.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031618062.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5872;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39	"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_031621660.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031639530.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031627338.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031619128.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_031623635.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031627660.1	3	Reactome: R-HSA-195399;Reactome: R-HSA-194313;Reactome: R-HSA-114608	"VEGF binds to VEGFR leading to receptor dimerization";"VEGF ligand-receptor interactions";"Platelet degranulation"
XP_031636723.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_031639933.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031634492.1	17	MetaCyc: PWY-5695;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-7179-1;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-74259;MetaCyc: PWY-4202	"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation II";"Guanosine nucleotides degradation III";"Purine metabolism";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Purine catabolism";"Arsenate detoxification I (mammalian)"
XP_031628150.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_031636226.1	13	MetaCyc: PWY-6807;Reactome: R-HSA-2022857;Reactome: R-HSA-4341670;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Defective NEU1 causes sialidosis";"Other glycan degradation";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"MPS IV - Morquio syndrome B";"Glycosphingolipid metabolism";"Galactose metabolism";"Neutrophil degranulation";"Glycosaminoglycan degradation";"HS-GAG degradation";"Sphingolipid metabolism"
XP_031617310.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_031623652.1	17	Reactome: R-HSA-2500257;Reactome: R-HSA-174178;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-6804756;Reactome: R-HSA-68877;Reactome: R-HSA-9022692;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Resolution of Sister Chromatid Cohesion";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI3K-Akt signaling pathway";"SUMOylation of DNA replication proteins";"Regulation of TP53 Activity through Phosphorylation";"Mitotic Prometaphase";"Regulation of MECP2 expression and activity";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_031625308.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_031629610.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_031639197.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031618477.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031620906.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_031635023.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031635765.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_031622941.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031625794.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_031636798.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031628337.1	13	MetaCyc: PWY-4061;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370	"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)"
XP_031622942.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031628834.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678	"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_031623171.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031628872.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031629998.1	5	KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_031627969.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-8939211	"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"ESR-mediated signaling"
XP_031640805.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031635941.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_031627765.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031632348.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031625597.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_031633528.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events"
XP_031632258.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031619036.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031639995.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031630365.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_031630159.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031621429.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_031617170.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Ion channel transport"
XP_031630150.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031623000.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031633304.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_031622540.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031623722.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_031640744.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031635678.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031630553.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_031622869.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events"
XP_031629743.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031622984.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031621488.1	12	KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385	"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Methane metabolism";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)"
XP_031622724.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031620182.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031628074.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031618985.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_031619402.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031631728.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031623065.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031620013.1	11	MetaCyc: PWY-6728;MetaCyc: PWY-7124;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268	"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_031640884.1	1	KEGG: 00910+4.2.1.104	"Nitrogen metabolism"
XP_031622189.1	12	Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-1169408	"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"ISG15 antiviral mechanism"
XP_031634596.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_031628908.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031619392.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_031639107.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_031633297.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031627347.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031637404.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031633532.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_031638907.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031638921.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_031635599.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_031639078.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031629611.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_031619923.1	7	MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469	"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis"
XP_031624759.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031622602.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_031629838.1	24	Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-392170;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-392851	"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"G-protein activation";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"ADP signalling through P2Y purinoceptor 12";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor"
XP_031626662.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031629667.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_031627313.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031629907.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031626332.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_031623937.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_031628101.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031632877.1	6	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_031640749.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031619378.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031622899.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_031617891.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_031627965.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_031620256.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230	"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane"
XP_031623802.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_031623317.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031627717.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031627566.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_031636995.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-1483166	"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Synthesis of PA"
XP_031627840.1	11	MetaCyc: PWY-5686;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;Reactome: R-HSA-500753;MetaCyc: PWY-7400;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791	"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis III"
XP_031627357.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031622034.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_031627093.1	4	Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532	"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer"
XP_031618224.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031622389.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870	"Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_031640026.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031638604.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7724	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_031631067.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031626780.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_031634733.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_031640510.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_031624115.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031626249.1	4	KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188	"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_031624607.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_031629074.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_031628008.1	33	MetaCyc: PWY-1801;MetaCyc: PWY-6342;MetaCyc: PWY-7798;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5480;MetaCyc: PWY-5078;KEGG: 00625+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-5082;MetaCyc: PWY-7013;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-5486;MetaCyc: PWY-3162;MetaCyc: PWY-6313;MetaCyc: PWY-7111;KEGG: 00980+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5751;MetaCyc: PWY-5057;MetaCyc: PWY-6802;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6871;Reactome: R-HSA-71384;KEGG: 00626+1.1.1.1	"Formaldehyde oxidation II (glutathione-dependent)";"Noradrenaline and adrenaline degradation";"Protein S-nitrosylation and denitrosylation";"Tyrosine metabolism";"L-leucine degradation III";"Retinol metabolism";"Chitin degradation to ethanol";"Pyruvate fermentation to ethanol I";"L-isoleucine degradation II";"Chloroalkane and chloroalkene degradation";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to ethanol III";"L-methionine degradation III";"(S)-propane-1,2-diol degradation";"Drug metabolism - cytochrome P450";"Acetaldehyde biosynthesis I";"Glycolysis / Gluconeogenesis";"L-phenylalanine degradation III";"Pyruvate fermentation to ethanol II";"L-tryptophan degradation V (side chain pathway)";"Serotonin degradation";"Pyruvate fermentation to isobutanol (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Methane metabolism";"Phenylethanol biosynthesis";"L-valine degradation II";"Salidroside biosynthesis";"Fatty acid degradation";"Butanol and isobutanol biosynthesis (engineered)";"Glycine, serine and threonine metabolism";"3-methylbutanol biosynthesis (engineered)";"Ethanol oxidation";"Naphthalene degradation"
XP_031618688.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031632608.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031620222.1	17	Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-3270619;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-1834949;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"IRF3-mediated induction of type I IFN";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Cytosolic sensors of pathogen-associated DNA";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence"
XP_031632714.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031623480.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_031631533.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031633535.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_031620807.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031629104.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_031641126.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_031628528.1	18	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PE"
XP_031640542.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_031640089.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_031636303.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_031641248.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-176034;Reactome: R-HSA-167243;Reactome: R-HSA-2173796;Reactome: R-HSA-9018519	"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Interactions of Tat with host cellular proteins";"Tat-mediated HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Estrogen-dependent gene expression"
XP_031632861.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_031630046.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031618747.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_031633401.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031630001.1	19	MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7222;Reactome: R-HSA-380320;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7226;Reactome: R-HSA-380270	"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes"
XP_031628900.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031638786.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_031621335.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_031634657.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping"
XP_031630263.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031634641.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_031632985.1	12	Reactome: R-HSA-5362798;Reactome: R-HSA-1251985;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-982772	"Release of Hh-Np from the secreting cell";"Nuclear signaling by ERBB4";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Growth hormone receptor signaling"
XP_031623429.1	19	Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828	"VLDL clearance";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Chylomicron clearance";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Chylomicron remodeling";"LDL remodeling";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis"
XP_031619947.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031638515.1	15	Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944	"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2"
XP_031617889.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_031637999.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031632328.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_031616801.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031630171.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_031632172.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_031639749.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_031637964.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031622219.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031636917.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031617596.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6811438	"RAB geranylgeranylation";"Intra-Golgi traffic"
XP_031619886.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_031640965.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_031637281.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_031629454.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_031616728.1	3	MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway"
XP_031628394.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031619826.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_031621105.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_031630625.1	5	MetaCyc: PWY-6853;Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88	"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism"
XP_031628147.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_031627846.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_031636124.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031635310.1	5	Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_031626993.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_031633663.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_031633324.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897	"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes"
XP_031631199.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031631108.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_031636611.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031619464.1	3	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation"
XP_031619741.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031639582.1	5	MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_031635067.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031617198.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031628292.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031624187.1	23	Reactome: R-HSA-392170;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-202040;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-416482	"ADP signalling through P2Y purinoceptor 12";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G-protein activation";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events"
XP_031638335.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_031623680.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_031619731.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031623507.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031621031.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-735;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6	"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism"
XP_031637405.1	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
XP_031637909.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation"
XP_031633115.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031633254.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031621070.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031636654.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031620769.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031617507.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_031626423.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_031625264.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_031632593.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_031626170.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_031617171.1	8	Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-9636467	"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification"
XP_031618975.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031632627.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_031635975.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_031627286.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_031616412.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031625307.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031626000.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_031617913.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031626501.1	5	Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I"
XP_031634318.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031620079.1	4	Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374	"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_031620408.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031628820.1	12	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;MetaCyc: PWY-7221	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Long-term potentiation";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis"
XP_031619750.1	37	Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-983170;Reactome: R-HSA-2467813;Reactome: R-HSA-204005;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-2132295;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749	"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Separation of Sister Chromatids";"COPII-mediated vesicle transport";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"MHC class II antigen presentation";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs"
XP_031619394.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031640492.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827	"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex"
XP_031639328.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031627061.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_031632170.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_031618384.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_031623196.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_031617363.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031632236.1	10	Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-111457;Reactome: R-HSA-3299685	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species"
XP_031626923.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031617815.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_031641092.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031624789.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031632242.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031625960.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031621550.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_031632614.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031629020.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_031629843.1	24	Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-400042	"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion"
XP_031623108.1	3	Reactome: R-HSA-4724325;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265	"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_031637515.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_031628757.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions"
XP_031619416.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031632663.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_031621245.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031624672.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031619796.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_031636385.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031619818.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_031626754.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031630596.1	5	KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4	"Geraniol degradation";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism"
XP_031633613.1	5	Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_031623702.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_031622657.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031630996.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031617449.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031621753.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins"
XP_031618642.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_031629986.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_031628925.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_031639065.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031636018.1	2	Reactome: R-HSA-75105;Reactome: R-HSA-389661	"Fatty acyl-CoA biosynthesis";"Glyoxylate metabolism and glycine degradation"
XP_031626750.1	9	Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031632987.1	11	Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9614657;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"FOXO-mediated transcription of cell death genes";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031621270.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_031630323.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_031625704.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_031627948.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031631807.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031628898.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031624321.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031634156.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031621304.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_031628989.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031625764.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_031634052.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_031625935.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418555	"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events"
XP_031641035.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031632607.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031635764.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_031624811.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_031633435.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031631836.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_031623701.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_031630441.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_031640773.1	8	MetaCyc: PWY-5738;MetaCyc: PWY-66;MetaCyc: PWY-5740;MetaCyc: PWY-7573;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;KEGG: 00051+4.2.1.47;KEGG: 00520+4.2.1.47	"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_031634319.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_031621238.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_031618237.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031629977.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031623632.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031622587.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_031632329.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_031628822.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_031622593.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031632707.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031621386.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_031631599.1	13	KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation"
XP_031636725.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031632480.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_031621059.1	4	MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_031636243.1	11	Reactome: R-HSA-1660517;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.137;Reactome: R-HSA-109704;MetaCyc: PWY-6352	"Synthesis of PIPs at the late endosome membrane";"Macroautophagy";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"PI3K Cascade";"3-phosphoinositide biosynthesis"
XP_031627613.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins"
XP_031618439.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031621098.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031618252.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031623491.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031623176.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031631254.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031617297.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_031633667.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_031637778.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_031625766.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_031638340.1	7	Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_031627285.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_031629664.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_031633525.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_031637521.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_031638121.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-113501	"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_031637686.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_031633502.1	9	MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle"
XP_031623873.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_031623326.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031621961.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425	"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_031632428.1	6	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-416993;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_031630105.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_031636386.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031625232.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031632981.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031630318.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031619869.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031629261.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_031640696.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031630320.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_031640290.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031621160.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031629369.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031624754.1	5	Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209560	"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival"
XP_031625487.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_031640288.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_031623867.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_031628832.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_031627986.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031621442.1	10	KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"PI3K-Akt signaling pathway";"RSK activation";"Thermogenesis"
XP_031633705.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031629477.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031627739.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031632211.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5693607	"Ub-specific processing proteases";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends"
XP_031622562.1	18	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_031641001.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_031627258.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_031617912.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031627571.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_031637098.1	30	Reactome: R-HSA-9614399;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-198693;Reactome: R-HSA-392451;Reactome: R-HSA-199418;Reactome: R-HSA-8948751;Reactome: R-HSA-6804758;KEGG: 05163+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-69202;Reactome: R-HSA-6804759;Reactome: R-HSA-69656;Reactome: R-HSA-9634638;Reactome: R-HSA-8941332;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-111447;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-8876198;KEGG: 04926+2.7.11.1	"Regulation of localization of FOXO transcription factors";"Thermogenesis";"Regulation of TP53 Degradation";"AKT phosphorylates targets in the nucleus";"G beta:gamma signalling through PI3Kgamma";"Negative regulation of the PI3K/AKT network";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Acetylation";"Human cytomegalovirus infection";"AKT-mediated inactivation of FOXO1A";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Cyclin E associated events during G1/S transition";"Regulation of TP53 Activity through Association with Co-factors";"Cyclin A:Cdk2-associated events at S phase entry";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RUNX2 regulates genes involved in cell migration";"PI3K-Akt signaling pathway";"CTLA4 inhibitory signaling";"Activation of BAD and translocation to mitochondria";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"RAB GEFs exchange GTP for GDP on RABs";"Relaxin signaling pathway"
XP_031623155.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031628056.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_031635108.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_031624388.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_031628783.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_031634277.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_031630041.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031630249.1	13	MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450"
XP_031639719.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483	"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)"
XP_031630423.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031625017.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_031640521.1	7	Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_031618954.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174178	"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_031617334.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031617063.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_031628501.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_031616893.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_031628849.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-180910	"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs"
XP_031624519.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031622023.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_031640332.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_031637517.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_031633255.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031639370.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031638205.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-191859	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly"
XP_031641255.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_031624936.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_031625685.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031625819.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031628680.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_031640173.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_031622553.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031636238.1	3	MetaCyc: PWY-1269;KEGG: 00540+2.7.7.38;Reactome: R-HSA-4085001	"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis";"Sialic acid metabolism"
XP_031620216.1	19	Reactome: R-HSA-3214858;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-8876725;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6790901	"RMTs methylate histone arginines";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Protein methylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol"
XP_031627449.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_031621344.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031620220.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_031630500.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031619726.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031624907.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_031637122.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_031639141.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_031639244.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_031638523.1	6	Reactome: R-HSA-71240;MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-6309;MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9	"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism"
XP_031626796.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_031625293.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031631710.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031623848.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_031618469.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_031626653.1	8	Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Activation of RAC1";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_031631654.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031621171.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_031631824.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_031639895.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031630179.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_031618015.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_031638547.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_031618606.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031619853.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_031619872.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_031638400.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031621861.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
XP_031618604.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031636508.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031623012.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031636770.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031627970.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"ESR-mediated signaling";"Attenuation phase"
XP_031638611.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031629905.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031627037.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_031630779.1	42	Reactome: R-HSA-110328;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-8936459;Reactome: R-HSA-9610379;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-212300;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-110331;Reactome: R-HSA-2559580	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Late Events";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PRC2 methylates histones and DNA";"G2/M DNA damage checkpoint";"Meiotic synapsis";"DNA methylation";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged purine";"Oxidative Stress Induced Senescence"
XP_031618342.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031628374.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031626692.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_031621715.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031619506.1	6	Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_031634841.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031616731.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031627209.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031622400.1	12	KEGG: 04151+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"PI3K-Akt signaling pathway";"G alpha (q) signalling events";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Thermogenesis";"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031641000.1	31	MetaCyc: PWY-6799;MetaCyc: PWY-8012;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-5971;MetaCyc: PWY-7723;MetaCyc: PWY-6282;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-5994;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-5989;Reactome: R-HSA-199220;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-5367;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-8049;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-7664	"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bacterial bioluminescence";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Petroselinate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)"
XP_031632411.1	29	Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-3108214;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606	"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"SUMOylation of DNA damage response and repair proteins";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_031635922.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_031627452.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031639880.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031626291.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_031624374.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031620304.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031633257.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031635859.1	52	Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-167290;Reactome: R-HSA-73980;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-73780;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-76071;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-72203;Reactome: R-HSA-167161	"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Chain Elongation";"mRNA Capping";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation"
XP_031630844.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism"
XP_031637509.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_031622907.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_031639367.1	6	MetaCyc: PWY-7285;Reactome: R-HSA-6787450;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;Reactome: R-HSA-8868766	"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"rRNA processing in the mitochondrion"
XP_031628603.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031625327.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_031622865.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594	"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events"
XP_031618730.1	6	KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241	"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import"
XP_031617038.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_031636581.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_031628389.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_031635356.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_031639784.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031632182.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_031624252.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031633288.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031628756.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178	"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans"
XP_031637785.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031630683.1	8	MetaCyc: PWY-3581;MetaCyc: PWY-6133;MetaCyc: PWY-5394;KEGG: 00790+1.14.16.2;KEGG: 00950+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5049	"(S)-reticuline biosynthesis I";"(S)-reticuline biosynthesis II";"Betalamic acid biosynthesis";"Folate biosynthesis";"Isoquinoline alkaloid biosynthesis";"Catecholamine biosynthesis";"Tyrosine metabolism";"Rosmarinic acid biosynthesis II"
XP_031636125.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031622765.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_031633808.1	5	KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3	"Pyrimidine metabolism";"Pyrimidine catabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes"
XP_031622719.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_031622254.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031640544.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031620377.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031619090.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031639847.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031639073.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_031638834.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_031635409.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031621305.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_031628392.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_031620277.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_031617022.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_031633489.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031622346.1	18	Reactome: R-HSA-167290;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-167243	"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery"
XP_031617710.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031640050.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031630057.1	13	Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206308;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;Reactome: R-HSA-4341670	"Neutrophil degranulation";"Glycosaminoglycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Galactose metabolism";"Other glycan degradation";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"MPS IV - Morquio syndrome B";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Defective NEU1 causes sialidosis"
XP_031616651.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031637698.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_031619703.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031622030.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031619600.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_031632482.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_031622728.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_031617227.1	5	MetaCyc: PWY-6386;MetaCyc: PWY-6387;KEGG: 00520+2.5.1.7;KEGG: 00550+2.5.1.7;MetaCyc: PWY-7953	"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"Amino sugar and nucleotide sugar metabolism";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)"
XP_031640362.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_031623018.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031620747.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_031632470.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_031631645.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031621547.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_031622930.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031632086.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_031621919.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031622316.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031624636.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_031628428.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031631145.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_031620089.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_031640695.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031630994.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031617126.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031629652.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031636794.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031618625.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_031624320.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031624589.1	8	MetaCyc: PWY-7179;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609	"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine metabolism";"Neutrophil degranulation";"Purine salvage";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III"
XP_031616920.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_031622482.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_031631651.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_031623353.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_031623097.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031626525.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031631466.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123	"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
XP_031641084.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_031633023.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031618276.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_031637379.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031639116.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_031629659.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031616401.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031623860.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_031637776.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_031621113.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031630383.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031632747.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483	"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_031639079.1	10	MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055	"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_031623847.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_031635079.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_031621633.1	15	Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_031625512.1	12	Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_031629900.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031634911.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031631315.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_031619440.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031619532.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031627140.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031628014.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_031628910.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031626267.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031640393.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-975634	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport"
XP_031619597.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_031619706.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031628093.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031630718.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-1655829	"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_031627292.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_031638857.1	30	Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1170546;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-5610783;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-8854050	"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI2 by the proteasome";"Iron uptake and transport";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_031628987.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031641210.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_031621186.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031637391.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031633757.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-7285;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-7286;MetaCyc: PWY-6829	"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)"
XP_031631816.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_031625905.1	22	MetaCyc: PWY-7728;MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7592;MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7601	"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_031638677.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_031623202.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_031617978.1	7	KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217;MetaCyc: PWY-7807;MetaCyc: PWY-7805;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-6610	"Purine metabolism";"Purine salvage";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation";"Adenine and adenosine salvage II";"Adenine salvage"
XP_031630170.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_031616762.1	5	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-983189;Reactome: R-HSA-5368286;Reactome: R-HSA-6811434	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Kinesins";"Mitochondrial translation initiation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031623325.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031632457.1	6	MetaCyc: PWY-7285;Reactome: R-HSA-6787450;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;Reactome: R-HSA-8868766	"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"rRNA processing in the mitochondrion"
XP_031625744.1	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_031633776.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_031636317.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031632253.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_031636523.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031622390.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695	"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation"
XP_031636589.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031620367.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events"
XP_031617583.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_031632416.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_031633072.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_031635022.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031620070.1	6	MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_031621132.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031633688.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670	"Sialic acid metabolism";"MHC class II antigen presentation";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis"
XP_031621923.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_031631769.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_031626997.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_031637376.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_031624820.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031634537.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_031619324.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_031625696.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031621752.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_031624103.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031625181.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_031621150.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031617109.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_031626583.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031618496.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031638820.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_031620176.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031621273.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_031623388.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_031637494.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_031622214.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031632417.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_031626460.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031640870.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_031624255.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031625276.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031640701.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031621875.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_031630592.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031619861.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_031623336.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031640463.1	20	KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5913;Reactome: R-HSA-1268020;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;Reactome: R-HSA-163765	"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Mitochondrial protein import";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"ChREBP activates metabolic gene expression"
XP_031626234.1	4	Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism"
XP_031620935.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031628188.1	44	Reactome: R-HSA-9634638;Reactome: R-HSA-375165;Reactome: R-HSA-9627069;Reactome: R-HSA-5654726;Reactome: R-HSA-8939211;Reactome: R-HSA-162658;Reactome: R-HSA-881907;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559585;Reactome: R-HSA-2871796;Reactome: R-HSA-5675221;Reactome: R-HSA-8943724;Reactome: R-HSA-879415;Reactome: R-HSA-8940973;Reactome: R-HSA-9649948;Reactome: R-HSA-170968;Reactome: R-HSA-112409;Reactome: R-HSA-2559582;Reactome: R-HSA-6802952;Reactome: R-HSA-982772;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-445144;Reactome: R-HSA-3371453;Reactome: R-HSA-450341;Reactome: R-HSA-5663213;Reactome: R-HSA-9635465;Reactome: R-HSA-5654733;Reactome: R-HSA-5654727;Reactome: R-HSA-444257;Reactome: R-HSA-6802948;Reactome: R-HSA-5674499;Reactome: R-HSA-198753;Reactome: R-HSA-202670;Reactome: R-HSA-5654732;Reactome: R-HSA-456926;Reactome: R-HSA-1295596;Reactome: R-HSA-6802955;Reactome: R-HSA-2029482;Reactome: R-HSA-2559580;Reactome: R-HSA-74749;Reactome: R-HSA-5668599;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"NCAM signaling for neurite out-growth";"Regulation of the apoptosome activity";"Negative regulation of FGFR1 signaling";"ESR-mediated signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Gastrin-CREB signalling pathway via PKC and MAPK";"mTOR signaling pathway";"Oncogene Induced Senescence";"FCERI mediated MAPK activation";"Negative regulation of MAPK pathway";"Regulation of PTEN gene transcription";"Advanced glycosylation endproduct receptor signaling";"RUNX2 regulates osteoblast differentiation";"Signaling downstream of RAS mutants";"Frs2-mediated activation";"RAF-independent MAPK1/3 activation";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling by BRAF and RAF fusions";"Growth hormone receptor signaling";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signal transduction by L1";"Regulation of HSF1-mediated heat shock response";"Activation of the AP-1 family of transcription factors";"RHO GTPases Activate WASPs and WAVEs";"Suppression of apoptosis";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR2 signaling";"RSK activation";"Signaling by high-kinase activity BRAF mutants";"Negative feedback regulation of MAPK pathway";"ERK/MAPK targets";"ERKs are inactivated";"Negative regulation of FGFR3 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Spry regulation of FGF signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of actin dynamics for phagocytic cup formation";"Oxidative Stress Induced Senescence";"Signal attenuation";"RHO GTPases Activate NADPH Oxidases";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade"
XP_031641086.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
XP_031616739.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_031628103.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031627379.1	13	Reactome: R-HSA-8876725;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-8866654;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-3371511;Reactome: R-HSA-6798695;Reactome: R-HSA-5689896;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768	"Protein methylation";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"E3 ubiquitin ligases ubiquitinate target proteins";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"HSF1 activation";"Neutrophil degranulation";"Ovarian tumor domain proteases";"Aggrephagy";"Translesion Synthesis by POLH";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_031624562.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031624957.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031626403.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031617162.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_031622368.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_031625416.1	33	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-3371453	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response"
XP_031622019.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_031622027.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_031618134.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_031628911.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031624120.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits"
XP_031625605.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031618879.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_031641102.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031625502.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_031626034.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031623185.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_031637217.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031626498.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749	"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I"
XP_031625045.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031638918.1	31	MetaCyc: PWY-5971;MetaCyc: PWY-7723;MetaCyc: PWY-6282;MetaCyc: PWY-6799;MetaCyc: PWY-8012;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;MetaCyc: PWY-5994;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-7858;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-5367;MetaCyc: PWY-5989;Reactome: R-HSA-199220;MetaCyc: PWY-8049;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-4381	"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bacterial bioluminescence";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_031630617.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_031640466.1	10	MetaCyc: PWY-5892;Reactome: R-HSA-2142789;MetaCyc: PWY-5895;MetaCyc: PWY-5891;MetaCyc: PWY-5844;MetaCyc: PWY-7996;MetaCyc: PWY-5849;MetaCyc: PWY-5890;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5839	"Menaquinol-12 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-7 biosynthesis"
XP_031631011.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031627770.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_031621437.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_031634485.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation"
XP_031623343.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031616654.1	40	Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-5601884;Reactome: R-HSA-77075	"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_031629826.1	57	Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-1169091	"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells"
XP_031627609.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_031624349.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_031636973.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031616960.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_031618169.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031632287.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031619690.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex"
XP_031618677.1	8	KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171	"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis"
XP_031618123.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031637309.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031623342.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031622551.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031618766.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_031638618.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031623570.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_031638388.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031633749.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031619529.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031618479.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031621158.1	32	Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167161	"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation"
XP_031623492.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_031625020.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_031631652.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_031626036.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031628902.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031623014.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_031628146.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_031636803.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031640742.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031630976.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68616	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_031632834.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_031618591.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_031632900.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031617080.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031627064.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031618570.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031618734.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_031635957.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-381038	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes"
XP_031624588.1	8	MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695	"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Neutrophil degranulation"
XP_031622605.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031629256.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031626799.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_031636799.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031635853.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_031622038.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031637021.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_031621201.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031624998.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_031621209.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_031640434.1	33	Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-3232142	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins"
XP_031620255.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230	"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane"
XP_031617092.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_031629996.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_031626474.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031637777.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_031635049.1	30	Reactome: R-HSA-2644607;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-1170546;Reactome: R-HSA-2644606;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-69231;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091	"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"Neddylation";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells"
XP_031632345.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031625612.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031626365.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_031623116.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031627823.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_031621157.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031635971.1	6	Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_031618558.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031630042.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_031630309.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031632699.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_031619347.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_031622533.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031626378.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_031629164.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-7328;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977	"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose catabolism";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_031629765.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031620285.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_031617225.1	5	KEGG: 00520+2.5.1.7;MetaCyc: PWY-7953;KEGG: 00550+2.5.1.7;MetaCyc: PWY-6386;MetaCyc: PWY-6387	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)"
XP_031620903.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_031628347.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031619783.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation"
XP_031624259.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_031638748.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_031619510.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031627985.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_031637420.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031625602.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031619302.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_031622439.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031635854.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_031623903.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_031636570.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031636637.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_031625391.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_031634252.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031638619.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031625914.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_031620087.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_031624104.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_031618871.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031618401.1	57	Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276	"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Downstream TCR signaling";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_031634614.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031618856.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031636327.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031619479.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_031635078.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_031628216.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_031618191.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_031618560.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031641005.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_031630382.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031618912.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_031624551.1	3	Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism"
XP_031640151.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_031631625.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_031632169.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_031633513.1	22	Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000	"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation"
XP_031631727.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031624319.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031632866.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7602	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_031636808.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-75105	"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis"
XP_031630663.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031620053.1	33	Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168276	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways"
XP_031633126.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031617701.1	13	KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7883	"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II"
XP_031616689.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_031635886.1	6	MetaCyc: PWY-7221;KEGG: 00790+6.3.4.20;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-6703;KEGG: 00230+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Folate biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Preq0 biosynthesis";"Purine metabolism"
XP_031624657.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_031623339.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031628344.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_031618214.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031619461.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-6790901	"Methylation";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol"
XP_031625678.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031634533.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_031627567.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_031629001.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_031629825.1	57	Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-187577	"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21"
XP_031623712.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031620543.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"Generic Transcription Pathway";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_031626515.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_031624945.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031627735.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_031627439.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031622460.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877	"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Gap junction assembly";"HCMV Early Events";"Aggrephagy";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase"
XP_031623298.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_031631235.1	12	Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6796648	"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_031632366.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031638822.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_031621726.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_031635527.1	26	Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-8866654;Reactome: R-HSA-6804114;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-4615885;Reactome: R-HSA-69183;Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-69205;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-1362277;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5656121	"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"E3 ubiquitin ligases ubiquitinate target proteins";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLK";"SUMOylation of DNA replication proteins";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"G1/S-Specific Transcription";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Transcription of E2F targets under negative control by DREAM complex";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI"
XP_031639663.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031635091.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_031627759.1	7	KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-7456	"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation"
XP_031638539.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_031634327.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031633560.1	30	Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-8941332;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-111447;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-6804759;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-5628897;Reactome: R-HSA-1358803;KEGG: 05170+2.7.11.1;Reactome: R-HSA-199418;Reactome: R-HSA-8948751;Reactome: R-HSA-6804758;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;Reactome: R-HSA-198693;Reactome: R-HSA-9614399;KEGG: 04714+2.7.11.1	"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"RAB GEFs exchange GTP for GDP on RABs";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RUNX2 regulates genes involved in cell migration";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"CTLA4 inhibitory signaling";"Activation of BAD and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Association with Co-factors";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"AKT-mediated inactivation of FOXO1A";"TP53 Regulates Metabolic Genes";"Downregulation of ERBB2:ERBB3 signaling";"Human immunodeficiency virus 1 infection";"Negative regulation of the PI3K/AKT network";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Acetylation";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"Thermogenesis"
XP_031620158.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_031639757.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_031626597.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_031631942.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_031620407.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_031631395.1	6	Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346;MetaCyc: PWY-7820	"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)"
XP_031622910.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_031628144.1	14	MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-181;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-2201	"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Photorespiration ";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"Metabolism of folate and pterines";"One carbon pool by folate";"Glycine betaine degradation I";"Folate transformations I"
XP_031620368.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events"
XP_031622986.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_031627771.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_031627911.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_031630439.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_031638377.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031623956.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031626131.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031616691.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031624384.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_031640610.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_031633595.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_031627624.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_031627361.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031629343.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031634557.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031618435.1	11	Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-193692	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR"
XP_031636172.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031620180.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031635090.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_031625931.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_031640781.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031627947.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031639427.1	6	Reactome: R-HSA-389661;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"Glyoxylate metabolism and glycine degradation";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_031630486.1	2	Reactome: R-HSA-8875656;Reactome: R-HSA-8873719	"MET receptor recycling";"RAB geranylgeranylation"
XP_031633599.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031619526.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031635504.1	15	Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
XP_031633403.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459	"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031630234.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107	"SUMOylation of chromatin organization proteins";"HCMV Early Events";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_031623224.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_031623371.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031638967.1	24	Reactome: R-HSA-444257;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-202424;Reactome: R-HSA-165158;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5218921;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-354192;Reactome: R-HSA-2730905	"RSK activation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Downstream TCR signaling";"Activation of AKT2";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated cell proliferation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization"
XP_031623113.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031617843.1	4	KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_031626835.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031637244.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_031630481.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_031639088.1	19	Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-7383;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;Reactome: R-HSA-71403;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5690;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37	"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism"
XP_031620261.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_031637417.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031630480.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_031616588.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_031640255.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031631647.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031638062.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_031640720.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031632867.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II"
XP_031638996.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism"
XP_031619068.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5	"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism"
XP_031633005.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031620225.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031640110.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980	"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Cristae formation";"Photosynthesis";"ATP biosynthesis"
XP_031625860.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_031634716.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031617008.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031618228.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031623009.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031637513.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_031635821.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031621315.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031617077.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031630796.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_031616327.1	6	MetaCyc: PWY-6367;Reactome: R-HSA-1660499;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64+3.1.3.95	"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_031628681.1	5	KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling"
XP_031626660.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031635833.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031619489.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031624173.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6798695	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation"
XP_031621326.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_031625060.1	11	Reactome: R-HSA-210455;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6963;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2	"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_031622479.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-203927	"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis"
XP_031637206.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_031627859.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_031632288.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_031618815.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122	"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis"
XP_031625541.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_031641100.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031638179.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031635089.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_031640573.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_031626749.1	9	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis"
XP_031638728.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031631698.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031629095.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-877300	"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"Interferon gamma signaling"
XP_031628817.1	12	Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308	"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor"
XP_031624139.1	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
XP_031620859.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_031619687.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031634590.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_031629774.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_031640725.1	56	Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-174184	"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Neddylation";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_031630357.1	4	MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4	"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Tryptophan metabolism"
XP_031627815.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_031635468.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state"
XP_031640518.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_031631715.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031625359.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_031638978.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS"
XP_031637980.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031616417.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031638906.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_031618846.1	11	MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381	"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)"
XP_031625706.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_031621082.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_031627445.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031620090.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_031620272.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031625580.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031637617.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031639120.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_031632389.1	5	KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-75109;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism"
XP_031616973.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031625081.1	8	KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-5740;MetaCyc: PWY-5739;MetaCyc: PWY-5738;MetaCyc: PWY-66	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)"
XP_031621903.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031618210.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031630068.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_031623567.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_031624686.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031624996.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_031623346.1	17	Reactome: R-HSA-5663220;KEGG: 04150+2.7.11.1;Reactome: R-HSA-141444;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-174178;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2500257;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2467813;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6804756;Reactome: R-HSA-4615885;Reactome: R-HSA-9022692	"RHO GTPases Activate Formins";"mTOR signaling pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Human papillomavirus infection";"Resolution of Sister Chromatid Cohesion";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Separation of Sister Chromatids";"Thermogenesis";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA replication proteins";"Regulation of MECP2 expression and activity"
XP_031625940.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway"
XP_031617341.1	7	MetaCyc: PWY-5188;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_031625269.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031623008.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_031621658.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031636547.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_031630119.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_031630913.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031625982.1	6	Reactome: R-HSA-9615017;MetaCyc: PWY-6854;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;Reactome: R-HSA-3299685	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Detoxification of Reactive Oxygen Species"
XP_031640292.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031627348.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031636807.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031624911.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_031617803.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_031625763.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_031632820.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_031622694.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system"
XP_031617090.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031636796.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031635472.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_031627545.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9620244	"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation"
XP_031619817.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_031618746.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_031619504.1	7	Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456	"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylketonuria"
XP_031627085.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_031621421.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_031618027.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_031616639.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_031636090.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031635829.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_031636811.1	10	Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590	"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling"
XP_031620955.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031629437.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_031619693.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031630214.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_031639903.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_031641256.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031627861.1	6	MetaCyc: PWY-7165;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Caprolactam degradation"
XP_031619505.1	29	KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6804757;Reactome: R-HSA-6803207;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693554;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6803204;Reactome: R-HSA-349425;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804760;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5693579;KEGG: 04926+2.7.11.1	"Thermogenesis";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Degradation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Autodegradation of the E3 ubiquitin ligase COP1";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"mTOR signaling pathway";"Regulation of TP53 Activity through Methylation";"Human papillomavirus infection";"Stabilization of p53";"Homologous DNA Pairing and Strand Exchange";"Relaxin signaling pathway"
XP_031633125.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031635177.1	15	Reactome: R-HSA-9665250;Reactome: R-HSA-9665244;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-9665233;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-5637810;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-9665251;Reactome: R-HSA-9665245;Reactome: R-HSA-9652282	"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to sapitinib";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Drug-mediated inhibition of ERBB2 signaling"
XP_031630943.1	5	Reactome: R-HSA-199220;MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012;MetaCyc: PWY-6289	"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein activation";"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism";"Petrobactin biosynthesis"
XP_031637443.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_031636458.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_031625596.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_031627858.1	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism";"Entner-Doudoroff pathway I"
XP_031619919.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_031627762.1	5	MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-7082	"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_031638813.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_031636001.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_031629177.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031640770.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031627699.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_031638957.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507	"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_031622349.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_031627803.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031639952.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5679001;MetaCyc: PWY-6972;Reactome: R-HSA-189483	"ABC-family proteins mediated transport";"Defective ABCC2 causes Dubin-Johnson syndrome";"Oleandomycin activation/inactivation";"Heme degradation"
XP_031621264.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031617949.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_031640955.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_031624129.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_031629899.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031622867.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594	"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events"
XP_031635736.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031634102.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031639842.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_031633164.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_031631868.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_031631758.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031623203.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_031619404.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031632057.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031640090.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_031617067.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_031617135.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031621754.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_031630693.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031633521.1	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_031631392.1	8	MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086	"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_031622872.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state"
XP_031639506.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031625544.1	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_031638089.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_031624243.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031619534.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_031620443.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031631057.1	4	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"ECM proteoglycans"
XP_031640787.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031637437.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_031627808.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838	"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO"
XP_031620486.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031630045.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031620045.1	17	Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_031633433.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_031641061.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_031630989.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-7659;MetaCyc: PWY-5123;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-6383	"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_031635069.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031633809.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031630597.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031622339.1	10	Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23	"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Galactose metabolism"
XP_031619543.1	5	Reactome: R-HSA-168638;Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24	"NOD1/2 Signaling Pathway";"p38MAPK events";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway"
XP_031617659.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs"
XP_031622101.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031636561.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_031639046.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031618349.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_031633117.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031639449.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031624572.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_031627642.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031619638.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9609690	"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"HCMV Early Events"
XP_031623478.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031630487.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031634315.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031639080.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587	"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)"
XP_031624525.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_031626871.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_031626701.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_031621693.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031634024.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031640992.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_031629930.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031617364.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031618691.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
XP_031640845.1	16	Reactome: R-HSA-1810476;Reactome: R-HSA-5602498;Reactome: R-HSA-9020702;Reactome: R-HSA-975871;Reactome: R-HSA-1257604;Reactome: R-HSA-5603037;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-5602680;Reactome: R-HSA-975155;Reactome: R-HSA-1236974;Reactome: R-HSA-166058;Reactome: R-HSA-3134963;Reactome: R-HSA-209543;Reactome: R-HSA-975138;Reactome: R-HSA-6811558	"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR2/4)";"Interleukin-1 signaling";"MyD88 cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 deficiency (TLR5)";"MyD88 dependent cascade initiated on endosome";"ER-Phagosome pathway";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"p75NTR recruits signalling complexes";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_031626467.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_031632108.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-182218	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation"
XP_031626095.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031632483.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_031619316.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_031639712.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_031632375.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031635653.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_031621936.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031640424.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_031635924.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_031640398.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Fructose and mannose metabolism"
XP_031637571.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031639243.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_031622801.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_031618277.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_031638181.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031633318.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_031636662.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_031618525.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5676590	"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling"
XP_031631037.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031623475.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031637434.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031626259.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031637807.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_031625332.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031633851.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_031636278.1	13	Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809	"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization"
XP_031638445.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_031630132.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031639458.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_031624736.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031617905.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Degradation of GLI2 by the proteasome";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_031626899.1	42	Reactome: R-HSA-3214841;Reactome: R-HSA-5250924;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-2299718;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-606279;Reactome: R-HSA-427389;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-201722;Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-2559580;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-5334118;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5578749;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-69473;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222	"PKMTs methylate histone lysines";"B-WICH complex positively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"Condensation of Prophase Chromosomes";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"RMTs methylate histone arginines";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"Oxidative Stress Induced Senescence";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"HDACs deacetylate histones";"DNA methylation";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation by small RNAs";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis"
XP_031632526.1	18	KEGG: 00640+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-70895;KEGG: 00310+1.8.1.4;KEGG: 00620+1.8.1.4;MetaCyc: PWY-5084;KEGG: 00280+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-6783984;Reactome: R-HSA-70268;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-71403;KEGG: 00010+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00020+1.8.1.4	"Propanoate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Lysine degradation";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation";"Glycine degradation";"Pyruvate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"Lysine catabolism";"Citric acid cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)"
XP_031636717.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_031616594.1	11	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-5685942	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)"
XP_031620380.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis"
XP_031626958.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031637500.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031626489.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031636812.1	10	Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664	"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation"
XP_031623233.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_031640883.1	1	KEGG: 00910+4.2.1.104	"Nitrogen metabolism"
XP_031622858.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031628918.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031619572.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_031624833.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_031618768.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031636800.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031621994.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes"
XP_031638664.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031625103.1	4	KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22	"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism"
XP_031636219.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_031628774.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_031640692.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031634710.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-6842	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II"
XP_031624872.1	6	MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-6731;MetaCyc: PWY-7238	"Glycogen degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch degradation III";"Sucrose biosynthesis II"
XP_031621403.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_031629742.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031635142.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031629839.1	24	Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-8964315	"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through BTK"
XP_031641195.1	83	Reactome: R-HSA-6807004;Reactome: R-HSA-5663213;Reactome: R-HSA-186763;Reactome: R-HSA-5655253;Reactome: R-HSA-9027284;Reactome: R-HSA-9664565;Reactome: R-HSA-5654688;Reactome: R-HSA-8853338;Reactome: R-HSA-179812;Reactome: R-HSA-1963640;Reactome: R-HSA-74749;Reactome: R-HSA-9607240;Reactome: R-HSA-1433559;Reactome: R-HSA-8983432;Reactome: R-HSA-9026519;Reactome: R-HSA-354194;Reactome: R-HSA-2871809;Reactome: R-HSA-167044;Reactome: R-HSA-5654732;Reactome: R-HSA-8856828;Reactome: R-HSA-1295596;Reactome: R-HSA-983695;Reactome: R-HSA-5654689;Reactome: R-HSA-2219530;Reactome: R-HSA-912526;Reactome: R-HSA-9634285;Reactome: R-HSA-8865999;Reactome: R-HSA-5637810;Reactome: R-HSA-1250347;Reactome: R-HSA-5654695;Reactome: R-HSA-9645135;Reactome: R-HSA-9028335;Reactome: R-HSA-5654704;Reactome: R-HSA-8851805;Reactome: R-HSA-112412;Reactome: R-HSA-74751;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-5654733;Reactome: R-HSA-5654727;Reactome: R-HSA-1963642;Reactome: R-HSA-8853334;Reactome: R-HSA-8875656;Reactome: R-HSA-5654693;Reactome: R-HSA-388841;Reactome: R-HSA-210993;Reactome: R-HSA-6811558;Reactome: R-HSA-1236382;Reactome: R-HSA-5673001;Reactome: R-HSA-5654699;Reactome: R-HSA-182971;Reactome: R-HSA-180292;Reactome: R-HSA-2029482;Reactome: R-HSA-5655291;Reactome: R-HSA-2730905;Reactome: R-HSA-5654719;Reactome: R-HSA-2871796;Reactome: R-HSA-2179392;Reactome: R-HSA-5655302;Reactome: R-HSA-8851907;Reactome: R-HSA-2428933;Reactome: R-HSA-109704;Reactome: R-HSA-8856825;Reactome: R-HSA-1257604;Reactome: R-HSA-5654706;Reactome: R-HSA-512988;Reactome: R-HSA-9034864;Reactome: R-HSA-5654710;Reactome: R-HSA-180336;Reactome: R-HSA-375165;Reactome: R-HSA-5654726;Reactome: R-HSA-5654720;Reactome: R-HSA-1250196;Reactome: R-HSA-1839117;Reactome: R-HSA-8875360;Reactome: R-HSA-5654712;Reactome: R-HSA-8853659;Reactome: R-HSA-391160;Reactome: R-HSA-389359;Reactome: R-HSA-5654700;Reactome: R-HSA-8875555;Reactome: R-HSA-2424491;Reactome: R-HSA-9028731	"Negative regulation of MET activity";"RHO GTPases Activate WASPs and WAVEs";"Downstream signal transduction";"Signaling by FGFR2 in disease";"Erythropoietin activates RAS";"Signaling by ERBB2 KD Mutants";"SHC-mediated cascade:FGFR1";"Signaling by FGFR3 point mutants in cancer";"GRB2 events in EGFR signaling";"GRB2 events in ERBB2 signaling";"Signal attenuation";"FLT3 Signaling";"Regulation of KIT signaling";"Interleukin-15 signaling";"Activated NTRK2 signals through RAS";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"FCERI mediated Ca+2 mobilization";"Signalling to RAS";"Negative regulation of FGFR3 signaling";"Clathrin-mediated endocytosis";"Spry regulation of FGF signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PI-3K cascade:FGFR1";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin receptor SHC signaling";"Constitutive Signaling by Overexpressed ERBB2";"MET activates PTPN11";"Constitutive Signaling by EGFRvIII";"SHC1 events in ERBB4 signaling";"PI-3K cascade:FGFR2";"STAT5 Activation";"Activated NTRK2 signals through PI3K";"SHC-mediated cascade:FGFR3";"MET activates RAS signaling";"SOS-mediated signalling";"Insulin receptor signalling cascade";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR2 signaling";"PI3K events in ERBB2 signaling";"Signaling by FGFR3 fusions in cancer";"MET receptor recycling";"FRS-mediated FGFR1 signaling";"Costimulation by the CD28 family";"Tie2 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"RAF/MAP kinase cascade";"SHC-mediated cascade:FGFR2";"EGFR downregulation";"GAB1 signalosome";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by FGFR4 in disease";"Role of LAT2/NTAL/LAB on calcium mobilization";"SHC-mediated cascade:FGFR4";"FCERI mediated MAPK activation";"EGFR Transactivation by Gastrin";"Signaling by FGFR1 in disease";"MET activates PI3K/AKT signaling";"SHC-related events triggered by IGF1R";"PI3K Cascade";"Cargo recognition for clathrin-mediated endocytosis";"PIP3 activates AKT signaling";"FRS-mediated FGFR3 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Activated NTRK3 signals through RAS";"PI-3K cascade:FGFR3";"SHC1 events in EGFR signaling";"NCAM signaling for neurite out-growth";"Negative regulation of FGFR1 signaling";"PI-3K cascade:FGFR4";"SHC1 events in ERBB2 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"InlB-mediated entry of Listeria monocytogenes into host cell";"FRS-mediated FGFR4 signaling";"RET signaling";"Signal regulatory protein family interactions";"CD28 dependent Vav1 pathway";"FRS-mediated FGFR2 signaling";"MET activates RAP1 and RAC1";"DAP12 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_031630664.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031621435.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031617201.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031627875.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
XP_031640513.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031641042.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_031622281.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031622362.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031625517.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031629683.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_031636991.1	33	Reactome: R-HSA-6796648;Reactome: R-HSA-69656;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167200	"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin A:Cdk2-associated events at S phase entry";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_031619964.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_031639484.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_031626360.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031622435.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031625737.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_031636538.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031619144.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031636312.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_031620753.1	4	KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Selenoamino acid metabolism"
XP_031617512.1	5	Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852	"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Macroautophagy"
XP_031636216.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031618215.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031640413.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_031639282.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_031630243.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_031641127.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031626751.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_031617621.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-74217;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine salvage";"Surfactant metabolism"
XP_031632196.1	4	Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50	"Metabolism of polyamines";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_031628293.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031618231.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031623393.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_031628770.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031626463.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_031624755.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_031616403.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031624761.1	7	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-110362	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair"
XP_031637518.1	57	Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-174184	"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_031623114.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031619793.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_031638760.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_031620863.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism"
XP_031631530.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031637811.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031637894.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031630829.1	11	Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Syndecan interactions";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_031622516.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_031633196.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_031626580.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_031617844.1	4	KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_031619896.1	11	Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"p38MAPK events";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031623344.1	17	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5663220;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-174178;Reactome: R-HSA-9648025;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2467813;Reactome: R-HSA-9022692;Reactome: R-HSA-4615885;Reactome: R-HSA-6804756;Reactome: R-HSA-68877;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"RHO GTPases Activate Formins";"Human papillomavirus infection";"Relaxin signaling pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"EML4 and NUDC in mitotic spindle formation";"Thermogenesis";"Separation of Sister Chromatids";"Regulation of MECP2 expression and activity";"SUMOylation of DNA replication proteins";"Regulation of TP53 Activity through Phosphorylation";"Mitotic Prometaphase";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_031633618.1	5	Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_031627915.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_031618225.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031620872.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_031633792.1	16	Reactome: R-HSA-5693548;Reactome: R-HSA-201722;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579	"Sensing of DNA Double Strand Breaks";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HATs acetylate histones";"Estrogen-dependent gene expression";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange"
XP_031636761.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031640868.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_031626274.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_031620244.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_031619301.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_031626789.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_031638953.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_031631072.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031639499.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"mTOR signalling"
XP_031625302.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_031620471.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_031627283.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031626485.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031641101.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031617247.1	5	MetaCyc: PWY-7953;KEGG: 00520+1.3.1.98;MetaCyc: PWY-6387;KEGG: 00550+1.3.1.98;MetaCyc: PWY-6386	"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)"
XP_031634221.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031626582.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031616925.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031637655.1	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_031634616.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031623354.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031619306.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_031636261.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_031622024.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_031638747.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_031630505.1	10	Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563	"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription"
XP_031619403.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031625008.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_031634685.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031620206.1	3	MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12	"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_031636915.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031625079.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031617591.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_031626959.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_031625330.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_031616432.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031633579.1	29	KEGG: 00626+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-7396;MetaCyc: PWY-5082;MetaCyc: PWY-6587;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6871;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-5078;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-7111;MetaCyc: PWY-6313;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-7118;MetaCyc: PWY-3162;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-6342	"Naphthalene degradation";"(S)-propane-1,2-diol degradation";"Butanol and isobutanol biosynthesis (engineered)";"L-methionine degradation III";"Pyruvate fermentation to ethanol III";"Glycine, serine and threonine metabolism";"3-methylbutanol biosynthesis (engineered)";"Fatty acid degradation";"Salidroside biosynthesis";"L-isoleucine degradation II";"Chloroalkane and chloroalkene degradation";"Phenylethanol biosynthesis";"alpha-Linolenic acid metabolism";"L-valine degradation II";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to isobutanol (engineered)";"Serotonin degradation";"Retinol metabolism";"L-leucine degradation III";"Chitin degradation to ethanol";"L-tryptophan degradation V (side chain pathway)";"Tyrosine metabolism";"Pyruvate fermentation to ethanol II";"Drug metabolism - cytochrome P450";"Acetaldehyde biosynthesis I";"Glycolysis / Gluconeogenesis";"L-phenylalanine degradation III";"Noradrenaline and adrenaline degradation"
XP_031618647.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031627775.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031626188.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031624054.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031619357.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_031630492.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-8001	"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_031619533.1	8	Reactome: R-HSA-1483148;KEGG: 00564+3.1.3.27;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Synthesis of PG";"Glycerophospholipid metabolism";"T cell receptor signaling pathway";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031624878.1	6	MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36;MetaCyc: PWY-7391	"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_031618616.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031622053.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031632595.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization"
XP_031624910.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_031630463.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031628495.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_031640267.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_031628305.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_031621035.1	3	Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987	"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis"
XP_031627395.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031624914.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_031636298.1	32	Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-6807505	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
XP_031620254.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230	"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane"
XP_031622399.1	12	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04151+2.7.11.1	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"G alpha (q) signalling events";"PI3K-Akt signaling pathway"
XP_031629323.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031624241.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031630962.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031627876.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031621956.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884	"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX"
XP_031640732.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_031630028.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_031630233.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_031639059.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_031621032.1	20	MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-735;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_031629509.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_031632988.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_031635232.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031636258.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031616509.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031632533.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_031630902.1	57	Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761	"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_031630912.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031619585.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031632233.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_031636241.1	9	MetaCyc: PWY-6964;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675	"Ammonia assimilation cycle II";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)"
XP_031632261.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031639682.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_031633044.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031616429.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031631718.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031637254.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031636781.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031616427.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031623189.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031627092.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
XP_031638032.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_031625878.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031628993.1	14	Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-68877;Reactome: R-HSA-428890;Reactome: R-HSA-5620912;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-380284;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Mitotic Prometaphase";"Role of ABL in ROBO-SLIT signaling";"Anchoring of the basal body to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Loss of proteins required for interphase microtubule organization from the centrosome";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2"
XP_031631461.1	11	Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation"
XP_031640743.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031626609.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031622541.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031638959.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_031631290.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_031637131.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031635650.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_031625776.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_031632174.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_031622157.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031622767.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_031626925.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031640577.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031630924.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031633527.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_031622028.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_031618663.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_031640203.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_031635027.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-7559	"Glutathione metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway"
XP_031641215.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_031622991.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_031636999.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_031640001.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism"
XP_031621195.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031637962.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031631770.1	14	Reactome: R-HSA-611105;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-3781	"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)"
XP_031625727.1	10	KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism"
XP_031620388.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_031624091.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_031625469.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031620020.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031638427.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031627988.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031629824.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601	"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_031628484.1	1	KEGG: 00906+1.23.5.1	"Carotenoid biosynthesis"
XP_031631585.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031630437.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_031626187.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-8856825	"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis"
XP_031641252.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031634247.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031640084.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_031640697.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_031640913.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_031627001.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_031623283.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_031623332.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031622448.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_031632317.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031624635.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_031631440.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031618311.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_031633600.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031619463.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_031641182.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031628223.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031631635.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_031638549.1	12	Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Activation of AMPK downstream of NMDARs";"Human papillomavirus infection";"Macroautophagy";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway"
XP_031621117.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_031631233.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167243	"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery"
XP_031625655.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031624568.1	7	MetaCyc: PWY-5265;MetaCyc: PWY-6471;KEGG: 00550+2.7.8.13;Reactome: R-HSA-446193;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;Reactome: R-HSA-4549356	"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2"
XP_031627774.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_031619076.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_031622814.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031638466.1	7	KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-8856828;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Clathrin-mediated endocytosis";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation"
XP_031623334.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031635301.1	5	KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-193048;Reactome: R-HSA-446199;Reactome: R-HSA-4755579	"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ"
XP_031631070.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031619395.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031626451.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757	"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Regulation of TP53 Degradation"
XP_031617628.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_031620474.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_031619360.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_031616688.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031636666.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_031638675.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031618278.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_031637782.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_031630593.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_031633396.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031637344.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031622707.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_031619318.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031625779.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_031629970.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031638701.1	34	Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-69656;Reactome: R-HSA-6782210;Reactome: R-HSA-167162	"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin A:Cdk2-associated events at S phase entry";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape"
XP_031617116.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031639212.1	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-5989;Reactome: R-HSA-199220;MetaCyc: PWY-7746;MetaCyc: PWY-8049;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;Reactome: R-HSA-75105;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-7723;MetaCyc: PWY-6282;MetaCyc: PWY-6799;MetaCyc: PWY-8012;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5994;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-7858	"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bacterial bioluminescence";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Biotin metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II"
XP_031616926.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031633779.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase"
XP_031631707.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031621912.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_031640198.1	3	Reactome: R-HSA-909733;Reactome: R-HSA-877300;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"Interferon gamma signaling";"OAS antiviral response"
XP_031631207.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_031625408.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031637361.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031632575.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031624219.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031633119.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031617311.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_031639598.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031640358.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_031633186.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031633959.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism"
XP_031621458.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_031628784.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031623150.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_031627890.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031625729.1	10	KEGG: 00332+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539	"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_031630337.1	18	MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1483166	"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA"
XP_031616927.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031619682.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_031637326.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031636785.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031625601.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_031617045.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884	"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX"
XP_031633112.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_031623477.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031625977.1	22	MetaCyc: PWY-5384;MetaCyc: PWY-6142;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-5054;MetaCyc: PWY-8013;KEGG: 00010+5.3.1.9;MetaCyc: PWY-622;MetaCyc: PWY-5659;MetaCyc: PWY-7347;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-6981;MetaCyc: PWY-7385;MetaCyc: PWY-5514;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-6992	"Sucrose degradation IV (sucrose phosphorylase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Sucrose degradation II (sucrose synthase)";"D-sorbitol biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis / Gluconeogenesis";"Starch biosynthesis";"GDP-mannose biosynthesis";"Sucrose biosynthesis III";"Gluconeogenesis";"Glycolysis";"Chitin biosynthesis";"1,3-propanediol biosynthesis (engineered)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism";"TP53 Regulates Metabolic Genes";"1,5-anhydrofructose degradation"
XP_031621373.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_031625236.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_031624737.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031616599.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031635968.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031620941.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031624849.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031622884.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_031618018.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_031640782.1	3	MetaCyc: PWY-6100;Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8	"L-carnitine biosynthesis";"Carnitine synthesis";"Lysine degradation"
XP_031624071.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031628596.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031627138.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_031626002.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_031618106.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_031633482.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_031626922.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_031622467.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_031621068.1	11	Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-6728;MetaCyc: PWY-7124;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913	"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)"
XP_031619069.1	8	MetaCyc: PWY-7181;Reactome: R-HSA-73614;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7193	"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I"
XP_031627910.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722	"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis"
XP_031639925.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_031634175.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_031627331.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031640378.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031630027.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_031633326.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031635320.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_031630321.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031621857.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031621314.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031628771.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_031638995.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-380284;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-141444;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Separation of Sister Chromatids";"Loss of proteins required for interphase microtubule organization from the centrosome";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_031628830.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_031624314.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031618505.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031621948.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593	"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity"
XP_031626534.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031619733.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031617965.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031630034.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031625682.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones"
XP_031630462.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_031627897.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_031626883.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_031619399.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031617127.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031621804.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_031638674.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_031632843.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_031627916.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_031632585.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031625398.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031631481.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_031619343.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031626074.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_031639696.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031637520.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031638562.1	19	Reactome: R-HSA-182971;Reactome: R-HSA-983231;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-8964616;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-5627123;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-418885	"EGFR downregulation";"Factors involved in megakaryocyte development and platelet production";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"G beta:gamma signalling through CDC42";"Myogenesis";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"RHO GTPases activate PAKs";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"DCC mediated attractive signaling"
XP_031631010.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031619490.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_031635940.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_031633612.1	17	Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031637676.1	30	Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-2644606;Reactome: R-HSA-5607761;Reactome: R-HSA-1170546;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-5610783;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-195253	"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Dectin-1 mediated noncanonical NF-kB signaling";"Prolactin receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI2 by the proteasome";"Iron uptake and transport";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex"
XP_031631459.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Myogenesis";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation"
XP_031640910.1	11	MetaCyc: PWY-5695;MetaCyc: PWY-5381;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-7185;MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821	"Inosine 5'-phosphate degradation";"Pyridine nucleotide cycling (plants)";"Adenosine nucleotides degradation I";"Purine metabolism";"Guanosine nucleotides degradation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis"
XP_031621566.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_031632876.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_031630503.1	10	Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_031635824.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031633014.1	6	MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_031636495.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031639076.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_031637377.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031621121.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-6708	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_031628284.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_031619003.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031631928.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231	"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_031635907.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662	"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism"
XP_031617274.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_031621901.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation"
XP_031640543.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031636512.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031626089.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031630984.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031632598.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation"
XP_031637445.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031636641.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031628711.1	52	Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-5617472;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-76071;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-73780;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-6782210;Reactome: R-HSA-73980	"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Termination"
XP_031621669.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031627131.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_031623736.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031624883.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_031634949.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_031617064.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_031633300.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031621380.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400253	"RORA activates gene expression";"snRNP Assembly";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock"
XP_031631611.1	26	Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-437239	"Separation of Sister Chromatids";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1"
XP_031636790.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031630440.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_031625049.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_031641112.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Peptide chain elongation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031619087.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031636721.1	9	MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-70263	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Gluconeogenesis"
XP_031626861.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_031637002.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_031627950.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031629784.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031631531.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031633154.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031627266.1	5	Reactome: R-HSA-111458;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109	"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism"
XP_031622442.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031635343.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031621308.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_031616911.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_031640367.1	7	Reactome: R-HSA-1474151;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-69205	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription"
XP_031635317.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_031616405.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031628208.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_031631648.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031629081.1	4	KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282	"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_031619233.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_031636718.1	9	Reactome: R-HSA-196780;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146	"Biotin transport and metabolism";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism"
XP_031628651.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031639369.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031640972.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031627758.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-7279;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)"
XP_031634050.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_031636091.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7724	"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_031623542.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_031627964.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_031631197.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031619196.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031627987.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031618209.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031634577.1	3	MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_031628413.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031621196.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031636740.1	52	Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-73780;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-5578749;Reactome: R-HSA-6796648;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-167162;Reactome: R-HSA-73980	"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Chain Elongation";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Transcriptional regulation by small RNAs";"TP53 Regulates Transcription of DNA Repair Genes";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Termination"
XP_031637296.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031638302.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031616596.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031631729.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031638762.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_031628586.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031630805.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031625389.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_031618089.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785	"Hedgehog 'on' state";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Neddylation";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome"
XP_031622145.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031628021.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_031640810.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans";"Non-integrin membrane-ECM interactions"
XP_031628044.1	42	Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-427389;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-606279;Reactome: R-HSA-9018519;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-171306;Reactome: R-HSA-3214858;Reactome: R-HSA-2299718;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-5250924;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-212300;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5578749;Reactome: R-HSA-5693607;Reactome: R-HSA-3214815;Reactome: R-HSA-5334118;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-2559580;Reactome: R-HSA-73728;Reactome: R-HSA-201722	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"Estrogen-dependent gene expression";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Packaging Of Telomere Ends";"RMTs methylate histone arginines";"Condensation of Prophase Chromosomes";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"B-WICH complex positively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"PRC2 methylates histones and DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation by small RNAs";"Processing of DNA double-strand break ends";"HDACs deacetylate histones";"DNA methylation";"Meiotic synapsis";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"Oxidative Stress Induced Senescence";"RNA Polymerase I Promoter Opening";"Formation of the beta-catenin:TCF transactivating complex"
XP_031625012.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_031639752.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_031639503.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_031625647.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031618526.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031634333.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031634432.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031636982.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031639419.1	52	Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-6796648;Reactome: R-HSA-73980;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-76071;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-73780;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-73779	"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Chain Elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_031616883.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031625029.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_031624687.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_031638226.1	29	Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-3108214;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938	"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)"
XP_031640719.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031637747.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031619791.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_031630482.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_031617569.1	17	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2467813;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9648025;Reactome: R-HSA-6804756;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9022692;Reactome: R-HSA-5663220;KEGG: 04150+2.7.11.1;Reactome: R-HSA-141444;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-174178;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2500257	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Separation of Sister Chromatids";"Thermogenesis";"EML4 and NUDC in mitotic spindle formation";"Regulation of TP53 Activity through Phosphorylation";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Regulation of MECP2 expression and activity";"RHO GTPases Activate Formins";"mTOR signaling pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Human papillomavirus infection";"Resolution of Sister Chromatid Cohesion"
XP_031630056.1	13	Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-2022857;MetaCyc: PWY-6807;Reactome: R-HSA-4341670	"Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Glycosphingolipid metabolism";"Galactose metabolism";"Other glycan degradation";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"MPS IV - Morquio syndrome B";"Keratan sulfate degradation";"Xyloglucan degradation II (exoglucanase)";"Defective NEU1 causes sialidosis"
XP_031636326.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031639081.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15	"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism"
XP_031624122.1	13	MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.66;KEGG: 00760+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Nicotinate and nicotinamide metabolism"
XP_031625717.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031635837.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_031633158.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_031622261.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031641148.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031622663.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031626875.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031631786.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031619145.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_031638504.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_031629782.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_031639934.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031627908.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_031622853.1	10	MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6362;MetaCyc: PWY-6554;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_031624627.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031617711.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_031631426.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_031618194.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031630552.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031620938.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031626753.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031631469.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031618946.1	7	MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7838;MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;Reactome: R-HSA-1660662	"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_031626068.1	17	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7226;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7187	"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_031623172.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031626030.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031640068.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_031624714.1	8	Reactome: R-HSA-5683826;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6611;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1	"Surfactant metabolism";"Purine salvage";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II"
XP_031626140.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031617506.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_031625899.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031621124.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031638465.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_031631809.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_031625551.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_031618643.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031630262.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_031623260.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031641220.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031628828.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_031623081.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031617079.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_031632260.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031633690.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_031627931.1	1	Reactome: R-HSA-2022923	"Dermatan sulfate biosynthesis"
XP_031624027.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031616788.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031630615.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_031636209.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031635891.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662	"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism"
XP_031628808.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031640993.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_031627502.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031630235.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031635800.1	7	MetaCyc: PWY-7294;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-6969;MetaCyc: PWY-7854;MetaCyc: PWY-7295;KEGG: 00620+2.3.3.9	"D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"L-arabinose degradation IV";"Pyruvate metabolism"
XP_031627429.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031621484.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031627002.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031640798.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031634125.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159236	"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031630453.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031624792.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031620649.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_031629137.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031626150.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031623633.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031627168.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031626722.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031630447.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_031630020.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031638430.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_031616371.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_031639153.1	42	Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-2559580;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-212300;Reactome: R-HSA-2299718;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-427389	"Meiotic synapsis";"DNA methylation";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"PRC2 methylates histones and DNA";"Condensation of Prophase Chromosomes";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_031627448.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_031623636.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031622992.1	9	KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-6901	"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation"
XP_031630713.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_031634714.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031630488.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031629094.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948	"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants"
XP_031621188.1	5	Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536	"Heme biosynthesis";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_031617914.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031630343.1	5	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_031633436.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031640619.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031631926.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231	"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_031619133.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031638303.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_031638903.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031629100.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031634607.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_031616929.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031620857.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_031625229.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031640511.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_031636323.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031633178.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031620072.1	6	MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_031619795.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_031619975.1	2	KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19	"Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism"
XP_031617472.1	9	MetaCyc: PWY-6455;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;MetaCyc: PWY-6454;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798	"Vancomycin resistance II";"Activation of SMO";"Ligand-receptor interactions";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Vancomycin resistance I";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell"
XP_031621996.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway"
XP_031633184.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_031623487.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031632927.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_031634085.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031623468.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031616928.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031627708.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_031619698.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031623044.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031623516.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031630563.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-166208	"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling"
XP_031617856.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_031638005.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_031631314.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_031619371.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex"
XP_031636998.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_031626960.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_031640567.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_031634858.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_031620495.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_031635234.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031618648.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031631272.1	12	MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;MetaCyc: PWY-7901;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-801;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-6936	"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)"
XP_031622447.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_031628121.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031629002.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_031617884.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031630613.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_031636319.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_031627167.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031634696.1	2	KEGG: 00770+2.1.2.11;MetaCyc: PWY-6654	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis III (archaebacteria)"
XP_031627083.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031639956.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_031640892.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031628877.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_031620227.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031629673.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_031640388.1	14	MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_031632996.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_031629176.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031617478.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031625215.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031634845.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events"
XP_031640197.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_031616695.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031639329.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031627438.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_031619792.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_031627265.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031634093.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-77588	"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_031634348.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031616810.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_031637496.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031632689.1	12	KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240	"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Tryptophan catabolism"
XP_031621438.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1489509	"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"DAG and IP3 signaling"
XP_031638249.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031629647.1	8	MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_031636344.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031620479.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_031625329.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_031639361.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_031624524.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826	"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_031633897.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031622509.1	9	Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_031621974.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031640575.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_031625689.1	12	Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4	"Transport and synthesis of PAPS";"Sulfur metabolism";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfite oxidation III";"Selenate reduction";"Purine metabolism";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis"
XP_031618035.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507	"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_031634620.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031623921.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_031631080.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031632556.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_031619321.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling by Hippo";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031629908.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031620639.1	5	MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Neutrophil degranulation"
XP_031626868.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700	"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_031627752.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_031633322.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700	"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_031624038.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031631505.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031636005.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_031636643.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031620098.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031628393.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_031638273.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_031631147.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031622511.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol"
XP_031636374.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031630666.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031630117.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_031625085.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_031636783.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031624912.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_031622940.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031638858.1	30	Reactome: R-HSA-2644607;Reactome: R-HSA-983168;Reactome: R-HSA-1170546;Reactome: R-HSA-2644606;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-69231;Reactome: R-HSA-5607764;Reactome: R-HSA-2122947;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091	"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"Iron uptake and transport";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1";"CLEC7A (Dectin-1) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells"
XP_031619273.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Rap1 signalling";"Ca2+ pathway";"cGMP effects"
XP_031631717.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031640425.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_031640200.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_031633259.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031618745.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_031632644.1	6	MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-5789	"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_031631463.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs"
XP_031620493.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_031622688.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-418597	"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"G alpha (z) signalling events"
XP_031630174.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_031640265.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_031630422.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031635233.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031640305.1	4	KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558	"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine"
XP_031618240.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031638420.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031634292.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_031637602.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031630975.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031639246.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_031623800.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_031629382.1	17	Reactome: R-HSA-5689880;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-975163;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-9645460;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-4086398	"Ub-specific processing proteases";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"Alpha-protein kinase 1 signaling pathway";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Ca2+ pathway"
XP_031631196.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031632733.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031625347.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031634488.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-163615	"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation"
XP_031616551.1	13	MetaCyc: PWY-6370;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-4061	"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I"
XP_031630038.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_031632040.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031617951.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_031629677.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_031632138.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031621272.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_031635927.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031635344.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031628298.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031622799.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_031617335.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_031627410.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031630022.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis"
XP_031623872.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_031622578.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_031631867.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031623268.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031616696.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031621564.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_031622530.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_031632346.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_031624209.1	6	MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;Reactome: R-HSA-74259	"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism"
XP_031640082.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_031624637.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031636910.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031629877.1	6	KEGG: 00710+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-1861;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway"
XP_031629146.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031640359.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_031637448.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031626258.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_031632735.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_031625572.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031617581.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_031634120.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031634747.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_031635469.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670	"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway"
XP_031622269.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_031630334.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_031629182.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_031630714.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_031620945.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_031624514.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_031619092.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_031640733.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_031628535.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031617942.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_031630048.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749	"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs"
XP_031621123.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031618212.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031636983.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031627175.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031627173.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031620480.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_031624648.1	10	KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"mTOR signaling pathway";"Ub-specific processing proteases";"PI3K-Akt signaling pathway";"HATs acetylate histones";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031618605.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031631431.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031637353.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031629121.1	9	KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367	"Inositol phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism"
XP_031634619.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031637833.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031629828.1	7	Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941	"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch degradation V";"Starch degradation II";"Starch and sucrose metabolism";"Glycogen degradation II"
XP_031631232.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167243	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery"
XP_031622246.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031620445.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_031619822.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_031625385.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_031631650.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031622811.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_031631008.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation"
XP_031640526.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_031621749.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031635943.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_031631750.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031636325.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_031618261.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_031625677.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_031632371.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031618295.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031634915.1	18	KEGG: 00710+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;Reactome: R-HSA-70263;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5913	"Carbon fixation in photosynthetic organisms";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)"
XP_031639554.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_031629508.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_031620491.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031619396.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_031624660.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_031630133.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_031638161.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_031636229.1	12	Reactome: R-HSA-196780;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+6.3.4.13;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6613;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Biotin transport and metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine metabolism";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_031617895.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_031623278.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_031636457.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_031631734.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031638961.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_031624760.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031638821.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_031618620.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031628962.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_031634071.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_031618948.1	7	KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7839	"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis"
XP_031633006.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031630178.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_031622284.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_031621460.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_031626123.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031618497.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031636786.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031624653.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_031627510.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_031625533.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_031625400.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-7285;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_031631383.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031631881.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031633327.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031622800.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_031616598.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031633140.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_031617582.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy"
XP_031640641.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_031618165.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_031626380.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_031622904.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_031618229.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031635080.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_031638382.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_031633616.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"Endogenous sterols";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_031617731.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_031620284.1	5	KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_031638276.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031617183.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031617672.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism"
XP_031623271.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031632304.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_031636924.1	5	KEGG: 00550+6.3.2.9;Reactome: R-HSA-196757;KEGG: 00471+6.3.2.9;MetaCyc: PWY-6387;MetaCyc: PWY-6386	"Peptidoglycan biosynthesis";"Metabolism of folate and pterines";"D-Glutamine and D-glutamate metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)"
XP_031625542.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_031623695.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_031616970.1	5	MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_031619890.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_031629783.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031623608.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031621900.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031634865.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031619350.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_031635849.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031631699.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031638963.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_031637442.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031629341.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_031626466.1	7	Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-114608	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation"
XP_031618611.1	3	Reactome: R-HSA-948021;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_031639357.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_031638134.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_031629315.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_031619729.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031640399.1	10	KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11	"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism"
XP_031622542.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_031640384.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031617111.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis"
XP_031631074.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031621933.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031626218.1	9	Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69183	"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand"
XP_031632155.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_031620446.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_031633536.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_031638824.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_031640776.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031626543.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition"
XP_031630349.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72187	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing"
XP_031638401.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031640632.1	40	Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167160	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_031630716.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_031636222.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031633123.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031628768.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_031639327.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031636387.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031621877.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031632289.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_031624563.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031632589.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031638383.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_031618183.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031618733.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031624189.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031635877.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031628041.1	6	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane"
XP_031628769.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_031637186.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031630925.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031634775.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_031630216.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_031634594.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_031620571.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031625635.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031631437.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_031628278.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
XP_031624649.1	9	Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972	"mTOR signalling";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_031637952.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031640748.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031641272.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031641037.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031634863.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031637693.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_031635029.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_031623674.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_031630599.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031616601.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031621998.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex"
XP_031616511.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031629340.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis"
XP_031619358.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_031635153.1	18	Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4	"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism"
XP_031638994.1	17	Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-6679;Reactome: R-HSA-196780;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5789	"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Carnitine metabolism";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_031616431.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031631328.1	3	Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-6785807	"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling"
XP_031626064.1	24	Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Ca2+ pathway"
XP_031640294.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031624577.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_031624253.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031640532.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_031637508.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation"
XP_031637918.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031635473.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_031627953.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
XP_031640677.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031628045.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031639440.1	13	MetaCyc: PWY-6969;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5690	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Methylaspartate cycle";"TCA cycle II (plants and fungi)"
XP_031640859.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031632374.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031618782.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_031635803.1	56	Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091	"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Activation of NF-kappaB in B cells"
XP_031633563.1	30	KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-8941332;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-111447;Reactome: R-HSA-69202;Reactome: R-HSA-6804759;Reactome: R-HSA-69656;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-211163;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-5628897;Reactome: R-HSA-6804758;Reactome: R-HSA-8948751;Reactome: R-HSA-199418;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;Reactome: R-HSA-198693;Reactome: R-HSA-9614399;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"RAB GEFs exchange GTP for GDP on RABs";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RUNX2 regulates genes involved in cell migration";"mTOR signaling pathway";"CTLA4 inhibitory signaling";"Activation of BAD and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Regulation of TP53 Activity through Association with Co-factors";"Cyclin A:Cdk2-associated events at S phase entry";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT-mediated inactivation of FOXO1A";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN stability and activity";"Negative regulation of the PI3K/AKT network";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"Thermogenesis"
XP_031619123.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031621523.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_031628950.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_031627936.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_031628776.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_031632210.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880	"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Ub-specific processing proteases"
XP_031626502.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210	"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_031638806.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
XP_031622736.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+"
XP_031620954.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031638836.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation"
XP_031627544.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-936837	"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases"
XP_031620750.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-190840	"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Cilium Assembly";"Gap junction assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_031624564.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031634051.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_031626606.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031630620.1	5	Reactome: R-HSA-70688;Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88	"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism"
XP_031619893.1	11	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"p38MAPK events";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Thermogenesis"
XP_031626062.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031619895.1	11	KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04150+2.7.11.1	"Thermogenesis";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"p38MAPK events";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"mTOR signaling pathway"
XP_031632259.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031617001.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031627430.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031633122.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031639979.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031635484.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031619223.1	14	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_031628209.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_031620278.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_031624999.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_031623011.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_031630222.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_031622422.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031632746.1	10	Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756	"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation"
XP_031620373.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events"
XP_031633185.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031621216.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031622002.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402	"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex"
XP_031636388.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031637788.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_031633775.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_031630158.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031639485.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_031621967.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031633278.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031628741.1	7	Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214	"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_031623372.1	13	Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-216083	"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen chain trimerization";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"ECM proteoglycans";"NCAM1 interactions";"Signaling by PDGF";"Integrin cell surface interactions"
XP_031632708.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Triglyceride catabolism"
XP_031623307.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031630502.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031622309.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031621204.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_031617261.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001	"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade"
XP_031625182.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_031628905.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031635779.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_031633145.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_031616727.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031629141.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031620271.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031625239.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_031624790.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_031632148.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031622951.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031633519.1	4	Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping"
XP_031628755.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-216083	"Syndecan interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Integrin cell surface interactions"
XP_031639577.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_031619852.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_031622446.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_031617202.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031625435.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031630454.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_031640254.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031623303.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_031640609.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_031640541.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
XP_031640181.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_031616510.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031616789.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_031627205.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031622875.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031621223.1	9	Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932	"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules"
XP_031617191.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031625773.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_031626412.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756	"Regulation of PTEN stability and activity";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation"
XP_031625328.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_031639082.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031626277.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_031627800.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_031621023.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031635548.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_031639543.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031631789.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_031629003.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_031634181.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031630780.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031626093.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031628434.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_031637769.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_031635137.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031636003.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_031635041.1	30	Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-2644606;Reactome: R-HSA-1170546;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-2122947;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-195253	"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Prolactin receptor signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Neddylation";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"Orc1 removal from chromatin";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"NOTCH1 Intracellular Domain Regulates Transcription";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex"
XP_031636372.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031632642.1	6	MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5744	"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation"
XP_031621596.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031623572.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_031631708.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_031616692.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_031627136.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_031631271.1	12	KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-2821;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240	"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Tryptophan catabolism"
XP_031628076.1	9	MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-6147;MetaCyc: PWY-7852;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6703	"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Preq0 biosynthesis"
XP_031637318.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031625534.1	8	MetaCyc: PWY-6372;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Myo-inositol biosynthesis"
XP_031634387.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_031634777.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_031619513.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_031623291.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase"
XP_031635337.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_031623142.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031616834.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031641147.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_031637320.1	13	Reactome: R-HSA-5674135;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1	"MAP2K and MAPK activation";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway"
XP_031636874.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031634210.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex"
XP_031638742.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031627422.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_031619381.1	5	Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_031623874.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_031638911.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_031637483.1	13	KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135	"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation"
XP_031618204.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031623007.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_031634813.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_031633580.1	29	MetaCyc: PWY-3162;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-7118;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-6342;MetaCyc: PWY-7013;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6802;KEGG: 00071+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-6587;MetaCyc: PWY-5082;MetaCyc: PWY-6871;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5078;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-6313;MetaCyc: PWY-7111	"L-tryptophan degradation V (side chain pathway)";"Retinol metabolism";"L-leucine degradation III";"Chitin degradation to ethanol";"Tyrosine metabolism";"Pyruvate fermentation to ethanol II";"Drug metabolism - cytochrome P450";"Acetaldehyde biosynthesis I";"Glycolysis / Gluconeogenesis";"L-phenylalanine degradation III";"Noradrenaline and adrenaline degradation";"(S)-propane-1,2-diol degradation";"Naphthalene degradation";"Salidroside biosynthesis";"Fatty acid degradation";"Glycine, serine and threonine metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol III";"L-methionine degradation III";"3-methylbutanol biosynthesis (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol I";"L-isoleucine degradation II";"alpha-Linolenic acid metabolism";"Phenylethanol biosynthesis";"Chloroalkane and chloroalkene degradation";"L-valine degradation II";"Serotonin degradation";"Pyruvate fermentation to isobutanol (engineered)"
XP_031625509.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_031616913.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_031616398.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031627913.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_031618778.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation"
XP_031619522.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031637687.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_031623793.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031623195.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_031623832.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031626092.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_031625073.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-159236	"snRNP Assembly";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031638285.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_031639512.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031621244.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_031619037.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031627538.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-5632928	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2"
XP_031635100.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031625384.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_031624738.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031622580.1	5	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway"
XP_031626395.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685942	"Translesion synthesis by POLK";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)"
XP_031626563.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_031631598.1	13	Reactome: R-HSA-1660662;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52	"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series"
XP_031632285.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_031631801.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_031628975.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-2500257;Reactome: R-HSA-380284;Reactome: R-HSA-2467813;Reactome: R-HSA-428890;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-68877;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-380270;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Resolution of Sister Chromatid Cohesion";"Loss of proteins required for interphase microtubule organization from the centrosome";"Separation of Sister Chromatids";"Role of ABL in ROBO-SLIT signaling";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins"
XP_031638248.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031635154.1	18	MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_031638349.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_031635955.1	12	Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_031640107.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_031629984.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_031619281.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis"
XP_031622143.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_031617746.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_031640545.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031634309.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031639338.1	4	Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_031628907.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_031635934.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031632596.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814	"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes"
XP_031623876.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_031636248.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031641150.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_031630992.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_031633189.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_031629512.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841	"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines"
XP_031617260.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001	"PI3K Cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade"
XP_031634556.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031636379.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031634689.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837	"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation"
XP_031632115.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031627144.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_031641152.1	17	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_031635820.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031628496.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_031623484.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_031617365.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_031633180.1	7	KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7219;MetaCyc: PWY-7234;Reactome: R-HSA-73817	"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis"
XP_031618016.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_031627892.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031625381.1	3	MetaCyc: PWY-6871;KEGG: 00290+2.3.3.13;KEGG: 00620+2.3.3.13	"3-methylbutanol biosynthesis (engineered)";"Valine, leucine and isoleucine biosynthesis";"Pyruvate metabolism"
XP_031619512.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_031640947.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_031626469.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_031621935.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031620727.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031619295.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_031621869.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031633138.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_031629626.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031619569.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505	"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
XP_031616905.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_031630830.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-202733;Reactome: R-HSA-3000170	"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Cell surface interactions at the vascular wall";"Syndecan interactions"
XP_031621194.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031618741.1	17	Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-174411	"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere"
XP_031619524.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031630054.1	13	Reactome: R-HSA-4341670;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695	"Defective NEU1 causes sialidosis";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation"
XP_031617930.1	4	MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_031633475.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_031630495.1	2	Reactome: R-HSA-8875656;Reactome: R-HSA-8873719	"MET receptor recycling";"RAB geranylgeranylation"
XP_031633432.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_031637380.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031627232.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031629506.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_031623001.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031622866.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state"
XP_031619959.1	4	KEGG: 00010+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00052+3.1.3.9	"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Gluconeogenesis";"Galactose metabolism"
XP_031623426.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983231	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production"
XP_031619595.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_031640606.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_031636026.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_031618250.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_031620720.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_031619319.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031637746.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031634486.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_031622547.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031618096.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_031638513.1	7	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_031628860.1	12	Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167243	"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_031627068.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031619531.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031628799.1	26	Reactome: R-HSA-9013695;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-1989781;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508	"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"RORA activates gene expression";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"PPARA activates gene expression";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_031627065.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031625898.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031630058.1	13	Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206308;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;Reactome: R-HSA-4341670	"Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Glycosphingolipid metabolism";"Galactose metabolism";"Other glycan degradation";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"MPS IV - Morquio syndrome B";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Defective NEU1 causes sialidosis"
XP_031622220.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031639875.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_031629688.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_031626468.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_031622702.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13	"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system"
XP_031630312.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Signaling by Hippo";"Thermogenesis"
XP_031637026.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_031626461.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_031637948.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031619647.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_031638159.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_031629800.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031630545.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031636945.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_031626402.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_031636719.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_031623869.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_031618170.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_031628302.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7	"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis"
XP_031626746.1	9	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_031634697.1	2	MetaCyc: PWY-6654;KEGG: 00770+2.1.2.11	"Phosphopantothenate biosynthesis III (archaebacteria)";"Pantothenate and CoA biosynthesis"
XP_031617660.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"O-linked glycosylation"
XP_031629179.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031617752.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_031627088.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
XP_031623331.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031628782.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_031626016.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_031636568.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_031632447.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_031641029.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031628468.1	9	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation"
XP_031631935.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031618232.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031628486.1	7	Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939	"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)"
XP_031630236.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031625368.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031632327.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_031621656.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_031635370.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_031617366.1	5	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation"
XP_031633503.1	12	KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4	"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Arachidonic acid metabolism"
XP_031627677.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031636503.1	17	MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-6644;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-4202	"Salinosporamide A biosynthesis";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine catabolism";"Arsenate detoxification I (mammalian)"
XP_031621646.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031630386.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_031621471.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_031632370.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031623763.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_031630795.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_031630959.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031638109.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_031622734.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031620145.1	52	Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-5617472;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-73780;Reactome: R-HSA-6781827;Reactome: R-HSA-76071;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-6796648;Reactome: R-HSA-203927	"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase III Chain Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"TP53 Regulates Transcription of DNA Repair Genes";"MicroRNA (miRNA) biogenesis"
XP_031640035.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_031640991.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_031632217.1	13	KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2160916	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation"
XP_031617245.1	5	KEGG: 00520+1.3.1.98;MetaCyc: PWY-7953;MetaCyc: PWY-6386;KEGG: 00550+1.3.1.98;MetaCyc: PWY-6387	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)"
XP_031630499.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031616805.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031618886.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_031641277.1	13	Reactome: R-HSA-177504;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-8856828	"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"Clathrin-mediated endocytosis"
XP_031631987.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031628539.1	6	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798;Reactome: R-HSA-2046105;Reactome: R-HSA-390247;Reactome: R-HSA-2046106;Reactome: R-HSA-5684045	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import";"Linoleic acid (LA) metabolism";"Beta-oxidation of very long chain fatty acids";"alpha-linolenic acid (ALA) metabolism";"Defective ABCD1 causes adrenoleukodystrophy (ALD)"
XP_031618227.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031624662.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
XP_031633284.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031630167.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_031640315.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_031628306.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_031633002.1	5	Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3	"Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes"
XP_031619681.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031627233.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_031617641.1	3	KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_031629112.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031633824.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_031626858.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700	"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_031640572.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_031635095.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_031625712.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_031624045.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_031637426.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_031628801.1	26	Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-933541;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-1989781;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-400253	"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"TRAF6 mediated IRF7 activation";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"PPARA activates gene expression";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock"
XP_031633524.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor"
XP_031634615.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031637001.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis"
XP_031630443.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_031627851.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_031631484.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_031629265.1	7	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;MetaCyc: PWY-7849;Reactome: R-HSA-5423646;MetaCyc: PWY-7394;MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Urate conversion to allantoin III";"Aflatoxin activation and detoxification";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Purine metabolism"
XP_031623401.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_031634053.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-8939236;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production"
XP_031631606.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_031623946.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031619641.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_031620226.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_031621237.1	2	KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26	"Starch and sucrose metabolism";"Galactose metabolism"
XP_031620442.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_031641225.1	7	KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-6596	"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I"
XP_031617362.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031617917.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031625278.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_031636531.1	8	Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_031618602.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031619684.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_031633360.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_031617732.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_031616409.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031633644.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"Degradation of the extracellular matrix";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
XP_031623562.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776	"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape"
XP_031638429.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_031620516.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_031619077.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_031616508.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_031628420.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031633003.1	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532	"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)"
XP_031624580.1	11	MetaCyc: PWY-6992;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-3861	"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Mannitol degradation II"
XP_031618495.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031620287.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_031625793.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031624469.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031630019.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_031638746.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_031627206.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031619251.1	14	KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-975634;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4	"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism"
XP_031633362.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_031617442.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031617428.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_031626931.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031633812.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_031636838.1	11	KEGG: 00760+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184	"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_031630245.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation"
XP_031627349.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031621743.1	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_031627796.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695	"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neutrophil degranulation"
XP_031617943.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_031624249.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031616732.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031640569.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_031635402.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_031634094.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation"
XP_031629174.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_031626876.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031621593.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031636322.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_031623982.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_031626049.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_031620789.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031620378.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031634078.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031619880.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_031625876.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_031623013.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_031628777.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_031637511.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_031620767.1	4	Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-166058	"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_031624667.1	7	Reactome: R-HSA-983231;Reactome: R-HSA-8943724;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569	"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"HDMs demethylate histones";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_031622537.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031618993.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031632992.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_031630247.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation"
XP_031633187.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031632468.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_031626035.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_031616924.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031638521.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031621411.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_031616595.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031629819.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_031632071.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_031636276.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-422356	"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion"
XP_031626226.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_031634695.1	2	KEGG: 00770+2.1.2.11;MetaCyc: PWY-6654	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis III (archaebacteria)"
XP_031622326.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_031626610.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031622931.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731	"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_031626101.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_031625010.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_031622348.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_031626136.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031635851.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_031631515.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031617502.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642	"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_031640881.1	1	KEGG: 00910+4.2.1.104	"Nitrogen metabolism"
XP_031641218.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_031628800.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031627925.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826	"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis"
XP_031637921.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031623692.1	7	KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-4702	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I"
XP_031640985.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_031616922.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_031631927.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_031626913.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_031635340.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism"
XP_031630308.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_031625013.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5358606	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_031640737.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031624378.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031640933.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031632896.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_031627358.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_031633474.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_031626866.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_031627666.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-983189	"MHC class II antigen presentation";"Intraflagellar transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins"
XP_031617110.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_031634554.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_031625702.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_031622659.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_031628758.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031619217.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_031632748.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209	"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_031622785.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_031627056.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031640718.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031633849.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_031620179.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_031617819.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_031638177.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031620708.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031633363.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_031627912.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_031622610.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031630927.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031622713.1	6	Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-416993	"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors"
XP_031620875.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031620245.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_031617333.1	4	MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis"
XP_031627440.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031618244.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031629423.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_031638668.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_031638105.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_031637584.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_031629645.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031627665.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295	"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"MHC class II antigen presentation"
XP_031630595.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031631906.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031626514.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031621301.1	12	KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"Methane metabolism";"Cis-genanyl-coa degradation";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis"
XP_031618019.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_031628469.1	9	Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696395	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER"
XP_031626712.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031634180.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031629931.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_031636792.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031637314.1	18	KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00710+2.6.1.1	"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms"
XP_031636763.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031619917.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_031627877.1	7	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-110362	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair"
XP_031640865.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-7717;MetaCyc: PWY-5651	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde"
XP_031627984.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_031640390.1	14	MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_031637447.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_031620545.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082	"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"PPARA activates gene expression";"RORA activates gene expression"
XP_031622552.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031640723.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031623221.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_031640024.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031633469.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031626257.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031620638.1	5	MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Neutrophil degranulation"
XP_031625367.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_031640615.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_031632313.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_031624028.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_031622369.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_031624244.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_031630151.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031625027.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877	"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Recycling pathway of L1";"HCMV Early Events";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase"
XP_031638128.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_031631492.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_031628513.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_031617248.1	5	MetaCyc: PWY-7953;KEGG: 00520+1.3.1.98;KEGG: 00550+1.3.1.98;MetaCyc: PWY-6386;MetaCyc: PWY-6387	"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"Amino sugar and nucleotide sugar metabolism";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)"
XP_031635328.1	5	Reactome: R-HSA-446199;Reactome: R-HSA-4755579;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048	"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Androgen biosynthesis"
XP_031632063.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_031621205.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_031620512.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_031633147.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_031641044.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_031634717.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031622594.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031624502.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031637321.1	13	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_031626181.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031633480.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_031625392.1	6	MetaCyc: PWY-7285;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-8868766	"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"rRNA processing in the mitochondrion"
XP_031621372.1	8	Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_031640605.1	5	MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336;Reactome: R-HSA-6798695;MetaCyc: PWY-7180	"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"Pentose phosphate pathway";"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation"
XP_031630509.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_031622403.1	12	KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK";"mTOR signaling pathway";"G alpha (q) signalling events";"PI3K-Akt signaling pathway";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_031617073.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_031621261.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_031640741.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031626723.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031631806.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_031630242.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-3928665	"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells"
XP_031638459.1	15	Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569	"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_031637498.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_031636239.1	3	MetaCyc: PWY-1269;Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38	"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Sialic acid metabolism";"Lipopolysaccharide biosynthesis"
XP_031634957.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031640825.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031630614.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_031640691.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_031638323.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_031622848.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_031619867.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031635512.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_031627300.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_031636274.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_031626171.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_031620330.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_031633183.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031637176.1	30	Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-8939902;Reactome: R-HSA-1170546;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-2871837	"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Orc1 removal from chromatin";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of RUNX2 expression and activity";"Prolactin receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation"
XP_031632958.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_031638195.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_031619055.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-168333	"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_031631684.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_031621129.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_031637656.1	9	Reactome: R-HSA-5632684;MetaCyc: PWY-6454;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;MetaCyc: PWY-6455;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Hedgehog 'on' state";"Vancomycin resistance I";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Vancomycin resistance II";"Activation of SMO";"Ligand-receptor interactions"
XP_031619988.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_031623954.1	3	Reactome: R-HSA-5632681;Reactome: R-HSA-525793;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Myogenesis";"Activation of SMO"
XP_031629902.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031636485.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_031625021.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_031620305.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_031636422.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031617818.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_031620337.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031640183.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_031640478.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031617280.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031626193.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Degradation of AXIN"
XP_031638214.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031637000.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi"
XP_031623588.1	25	Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-381771;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392451	"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma"
XP_031636801.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_031616573.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_031635470.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism"
XP_031630172.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_031640027.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031622557.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031640304.1	4	Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20	"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Cysteine and methionine metabolism"
XP_031635822.1	5	Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_031635073.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_031634027.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-5173105	"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation"
XP_031617592.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_031616430.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031636806.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_031618916.1	5	KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_031621134.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_031623540.1	7	KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11	"Fructose and mannose metabolism";"Methane metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_031632700.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_031630230.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_031617402.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_031632743.1	10	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-163680	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"AMPK inhibits chREBP transcriptional activation activity"
XP_031616574.1	3	Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151	"eNOS activation";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_031630535.1	12	MetaCyc: PWY-5857;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5870	"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_031617593.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-8852276	"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_031636990.1	33	Reactome: R-HSA-6796648;Reactome: R-HSA-69656;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-69202;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-167158	"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin A:Cdk2-associated events at S phase entry";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Cyclin E associated events during G1/S transition";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex"
XP_031631069.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031623279.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_031633181.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_031626873.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_031616923.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_031630536.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031618598.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_031631843.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_031627743.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_031619707.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031630594.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_031620759.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_031620071.1	6	MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-3341	"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)"
XP_031640789.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031621761.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031631250.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_031624819.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_031633439.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_031632244.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_031635910.1	7	MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23	"UMP biosynthesis I";"Drug metabolism - other enzymes";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism"
XP_031631732.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_031627614.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_031621374.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_031626852.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_031617853.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_031640628.1	10	MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45;KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841;Reactome: R-HSA-499943;MetaCyc: PWY-7199;Reactome: R-HSA-69205;MetaCyc: PWY-7187;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"One carbon pool by folate";"Folate transformations II (plants)";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_031627257.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_031639251.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_031620289.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism"
XP_031621285.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_031640862.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_031627878.1	7	Reactome: R-HSA-110362;Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"POLB-Dependent Long Patch Base Excision Repair";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_031633328.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_031628533.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_031640274.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_031627632.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_031632150.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031624913.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_031618442.1	5	MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317	"Stachyose degradation";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
XP_031630215.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_031622371.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_031627166.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174178	"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_031638439.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_031638647.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_031639636.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031640936.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031616750.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_031639601.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_031625105.1	4	MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism"
XP_031618412.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031638958.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_031638173.1	30	Reactome: R-HSA-2122947;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-1170546;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-2565942	"NOTCH1 Intracellular Domain Regulates Transcription";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Prolactin receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Neddylation";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Regulation of PLK1 Activity at G2/M Transition"
XP_031635856.1	7	Reactome: R-HSA-5578999;MetaCyc: PWY-8043;MetaCyc: PWY-7255;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Glutathione metabolism"
XP_031631079.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_031637690.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_031618600.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031628984.1	14	Reactome: R-HSA-5620912;Reactome: R-HSA-428890;Reactome: R-HSA-68877;Reactome: R-HSA-2565942;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Role of ABL in ROBO-SLIT signaling";"Mitotic Prometaphase";"Regulation of PLK1 Activity at G2/M Transition";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes"
XP_031627882.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031632273.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_031635030.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_031618245.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_031625337.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_031640950.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_031641090.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031633523.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592	"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1"
XP_031640715.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080	"Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)"
XP_031625750.1	3	Reactome: R-HSA-73614;KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Pyrimidine salvage";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_031626133.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_031632702.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition"
XP_031636528.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031635077.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_031631600.1	13	KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid metabolism"
XP_031627069.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_031633323.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944	"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2"
XP_031627612.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic"
XP_031616565.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813	"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Separation of Sister Chromatids"
XP_031620404.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_031636378.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031617825.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_031634279.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_031626904.1	11	Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_031631119.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031617115.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031636227.1	13	KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206308;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4085001;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;Reactome: R-HSA-4341670;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-1660662	"Glycosphingolipid biosynthesis - ganglio series";"MPS IV - Morquio syndrome B";"Other glycan degradation";"Sialic acid metabolism";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Defective NEU1 causes sialidosis";"Sphingolipid metabolism";"HS-GAG degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Galactose metabolism";"Glycosphingolipid metabolism"
XP_031634796.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_031623445.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_031635641.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_031631245.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-75105	"Glyoxylate metabolism and glycine degradation";"Fatty acyl-CoA biosynthesis"
XP_031617279.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_031634946.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_031638766.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_031637077.1	11	MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-5123;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7560;MetaCyc: PWY-7524;MetaCyc: PWY-6859;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway III (archaea)";"All-trans-farnesol biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_031620841.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_031632136.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031638163.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_031618205.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_031640956.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_031640486.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031636404.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_031625421.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_031633582.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_031631195.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031639957.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_031640616.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_031629983.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_031628335.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_031618312.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_031621323.1	11	MetaCyc: PWY-7947;MetaCyc: PWY-7939;MetaCyc: PWY-5943;MetaCyc: PWY-6279;MetaCyc: PWY-7591;MetaCyc: PWY-5947;Reactome: R-HSA-1989781;KEGG: 00906+2.5.1.32+5.5.1.19;MetaCyc: PWY-7938;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"Flexixanthin biosynthesis";"Chlorobactene biosynthesis";"Beta-carotene biosynthesis";"Myxol-2' fucoside biosynthesis";"Okenone biosynthesis";"Lutein biosynthesis";"PPARA activates gene expression";"Carotenoid biosynthesis";"Isorenieratene biosynthesis I (actinobacteria)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_031626219.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_031616679.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_031626448.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_031619683.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_031621634.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_031633479.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_031636981.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_031635247.1	5	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_031630993.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_031624073.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985	"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose"
XP_031632898.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_031622405.1	12	Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (q) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_031635084.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_031631720.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_031638326.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031638310.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_031621384.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_031623149.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_031632597.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization"
XP_031623868.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_031625306.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-933541	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation"
XP_031637295.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_031619961.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_031618184.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_031625237.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_031638218.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_031637849.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_031635942.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_031619820.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_031634018.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_031638776.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425	"Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_031636281.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_031629962.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_031630558.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_031629145.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_031621234.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_031621947.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944	"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by MECP2"
XP_031640480.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_031630190.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001	"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_031637780.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_031618014.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_031628476.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_031622436.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_031637718.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_031633334.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_031617515.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_031629686.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_031616600.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_031628653.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_031623969.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_031631060.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031628831.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_031622549.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031628749.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_031628391.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_031637312.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_031622546.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_031626536.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_031619426.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_031639723.1	5	Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-983168	"Amyloid fiber formation";"Josephin domain DUBs";"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031627795.1	52	Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-5678895	"Degradation of AXIN";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis"
XP_031621128.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_031627615.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_031627428.1	6	MetaCyc: PWY-6527;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317	"Stachyose degradation";"Galactose catabolism";"Galactose metabolism";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
XP_031617444.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_031625733.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_031630501.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_031619255.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_031638475.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_031636377.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_031632350.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_031627934.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_031622990.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"