Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_050040906.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050034060.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050044696.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport"
XP_050023161.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050049554.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress"
XP_050035472.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974	"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway"
XP_050023141.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050039518.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-606279	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050023602.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050036658.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050047996.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5673000	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"RAF activation"
XP_050030829.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050032133.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050042562.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_050042776.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050025616.1	13	KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Keratan sulfate degradation"
XP_050042768.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050044797.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050036381.1	11	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"Ub-specific processing proteases";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050023576.1	15	Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152	"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_050047136.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052	"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion"
XP_050044189.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050023761.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050048386.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6	"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism"
XP_050044596.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2	"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling";"T cell receptor signaling pathway"
XP_050037166.1	18	MetaCyc: PWY-7115;MetaCyc: PWY-561;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Pyruvate metabolism"
XP_050023726.1	32	Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_050038338.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050033368.1	34	Reactome: R-HSA-69273;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-69656;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-69202;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-69231;Reactome: R-HSA-6796648;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167152	"Cyclin A/B1/B2 associated events during G2/M transition";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin D associated events in G1";"TP53 Regulates Transcription of DNA Repair Genes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_050034316.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050034518.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_050035801.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050026935.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050038121.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_050029578.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_050026103.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050040897.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_050042703.1	13	KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-5392	"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II"
XP_050051745.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050026752.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_050030767.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050044114.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050025930.1	4	KEGG: 00410+4.1.1.9;KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247	"beta-Alanine metabolism";"Propanoate metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids"
XP_050024740.1	18	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050032817.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050049830.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050044609.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_050030699.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050049318.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050023594.1	3	KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050029380.1	19	Reactome: R-HSA-3214858;Reactome: R-HSA-8876725;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"RMTs methylate histone arginines";"Protein methylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_050036377.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050036005.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane"
XP_050049301.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050042105.1	24	Reactome: R-HSA-163560;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-392517;Reactome: R-HSA-5610785;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-9634600;Reactome: R-HSA-163358;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-422356;Reactome: R-HSA-4420097;Reactome: R-HSA-5610783;Reactome: R-HSA-111931;Reactome: R-HSA-9010642;Reactome: R-HSA-180024;Reactome: R-HSA-8963896;Reactome: R-HSA-5687128;Reactome: R-HSA-8853659;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5621575;KEGG: 04150+2.7.11.11	"Triglyceride catabolism";"PKA activation";"PKA activation in glucagon signalling";"Rap1 signalling";"GLI3 is processed to GLI3R by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"PKA-mediated phosphorylation of key metabolic factors";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"Regulation of insulin secretion";"VEGFA-VEGFR2 Pathway";"Degradation of GLI2 by the proteasome";"PKA-mediated phosphorylation of CREB";"ROBO receptors bind AKAP5";"DARPP-32 events";"HDL assembly";"MAPK6/MAPK4 signaling";"RET signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"CD209 (DC-SIGN) signaling";"mTOR signaling pathway"
XP_050029333.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050051717.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050026328.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050036244.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050050695.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9617324	"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_050039289.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_050045179.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050049576.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_050027018.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105	"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation"
XP_050046114.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050049613.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050042718.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050044976.1	13	MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-6901;KEGG: 00260+5.4.2.12;MetaCyc: PWY-7124;MetaCyc: PWY-7003;KEGG: 00010+5.4.2.12;MetaCyc: PWY-6886;MetaCyc: PWY-5723;KEGG: 00680+5.4.2.12	"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycine, serine and threonine metabolism";"Ethylene biosynthesis V (engineered)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Methane metabolism"
XP_050029851.1	17	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050028323.1	29	Reactome: R-HSA-5693579;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-6803207;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-6804760;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-349425;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;KEGG: 05163+2.7.11.1	"Homologous DNA Pairing and Strand Exchange";"mTOR signaling pathway";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"Stabilization of p53";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Thermogenesis";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Methylation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Autodegradation of the E3 ubiquitin ligase COP1";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Human cytomegalovirus infection"
XP_050049484.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050027346.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050034748.1	3	KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
XP_050049156.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050031245.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050042295.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050052201.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-6782315	"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Methylation";"tRNA modification in the nucleus and cytosol"
XP_050023067.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027315.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050036524.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050030760.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050022495.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050034966.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050033687.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050032688.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_050040258.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050035324.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_050052764.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_050050832.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050025018.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_050030856.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050046125.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050049202.1	18	MetaCyc: PWY-7115;MetaCyc: PWY-7383;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00350+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00950+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Tyrosine metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Isoquinoline alkaloid biosynthesis"
XP_050047302.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050022520.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis"
XP_050025919.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_050026279.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050049682.1	3	KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590	"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation"
XP_050035865.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050048548.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050049759.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-190840	"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_050039087.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_050047588.1	15	Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167287	"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery"
XP_050049139.1	9	MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822	"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_050045543.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050051987.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050039951.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_050027553.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050035421.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050025476.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_050036619.1	4	Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230	"Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane"
XP_050040330.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050041708.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050035826.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050026027.1	10	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Thermogenesis";"RSK activation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050043355.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050032741.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050023796.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"VLDL assembly";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Chylomicron remodeling";"VLDL clearance";"Scavenging by Class F Receptors";"Chylomicron assembly";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Post-translational protein phosphorylation"
XP_050042611.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050040975.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050048935.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785	"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome"
XP_050039783.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050035197.1	12	MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4	"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_050050504.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050035989.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050050885.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050038033.1	9	MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-6142;Reactome: R-HSA-1475029	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide"
XP_050043437.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050036388.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050027587.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050052682.1	10	MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-3841	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Folate transformations II (plants)"
XP_050050532.1	29	Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-5696395;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-3108214;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-5651801;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"SUMOylation of DNA damage response and repair proteins";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"PCNA-Dependent Long Patch Base Excision Repair";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
XP_050047806.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050041846.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050044441.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050051139.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_050043917.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050052055.1	26	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes"
XP_050040105.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6	"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_050051796.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050022604.1	16	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-5693607;Reactome: R-HSA-9018519;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-201722;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"Processing of DNA double-strand break ends";"Estrogen-dependent gene expression";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Formation of the beta-catenin:TCF transactivating complex";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050026968.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_050045532.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_050048406.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050036571.1	5	KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426	"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050034960.1	17	KEGG: 05165+2.7.11.1;Reactome: R-HSA-75035;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-69601;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1433557	"Human papillomavirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human immunodeficiency virus 1 infection";"Transcriptional Regulation by E2F6";"Thermogenesis";"G2/M DNA damage checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Human cytomegalovirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Signaling by SCF-KIT"
XP_050042364.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_050052547.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050050819.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_050034934.1	6	MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-163560	"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol degradation I";"Triglyceride catabolism"
XP_050025339.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_050049300.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050046664.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_050026809.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690	"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"HCMV Early Events"
XP_050045335.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050040709.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050045116.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050039582.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050026077.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050052271.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050026501.1	5	MetaCyc: PWY-7176;MetaCyc: PWY-7185;MetaCyc: PWY-7177;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2	"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_050037136.1	30	Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-2564830;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape"
XP_050033935.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050035553.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050043000.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050044198.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_050034258.1	6	KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52	"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Cysteine and methionine metabolism";"Methane metabolism";"Vitamin B6 metabolism"
XP_050036611.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050048209.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050026078.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050034700.1	5	Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_050023174.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_050044251.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050026223.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_050038525.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050028336.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050033093.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_050030452.1	4	Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-6799198	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis"
XP_050024514.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050041907.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050023672.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050047071.1	8	KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1	"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Fructose and mannose metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis"
XP_050036133.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050025363.1	8	KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7181;Reactome: R-HSA-73614;MetaCyc: PWY-7193;Reactome: R-HSA-6798695	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation"
XP_050023469.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050025236.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_050023813.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_050050591.1	6	Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690	"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events"
XP_050042400.1	6	KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-622;Reactome: R-HSA-3322077;MetaCyc: PWY-5067;MetaCyc: PWY-7900	"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_050038619.1	9	MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2	"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis"
XP_050050055.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050044219.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050039390.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050024120.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_050023143.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050031041.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050032255.1	11	KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-5154;MetaCyc: PWY-5686;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790	"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"UMP biosynthesis II"
XP_050046184.1	9	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-6798695;Reactome: R-HSA-174577;Reactome: R-HSA-198933;Reactome: R-HSA-173736;Reactome: R-HSA-977606;Reactome: R-HSA-381426	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"Neutrophil degranulation";"Activation of C3 and C5";"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell";"Alternative complement activation";"Regulation of Complement cascade";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050044654.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131	"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR"
XP_050043726.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050026023.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050047026.1	10	MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051	"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis I"
XP_050052583.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050025719.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050047331.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050033237.1	57	Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664	"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation"
XP_050041843.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050050472.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_050041927.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050029446.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050049433.1	3	Reactome: R-HSA-532668;MetaCyc: PWY-7511;Reactome: R-HSA-901032	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)"
XP_050025921.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_050049354.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050031045.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050045002.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050038701.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_050040703.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050049441.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_050048771.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050026186.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050050911.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050051691.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050024661.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-1300642;Reactome: R-HSA-1222556	"Neutrophil degranulation";"Sperm Motility And Taxes";"ROS and RNS production in phagocytes"
XP_050028001.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050024687.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050028042.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050027605.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050034331.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050039029.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314	"Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050050682.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892	"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation"
XP_050023905.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_050050094.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050024498.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050049500.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989	"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_050027409.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050033476.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050050202.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism"
XP_050025599.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050027385.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050041368.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050048631.1	9	MetaCyc: PWY-6983;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-7852	"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)"
XP_050042175.1	6	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism"
XP_050025589.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050024316.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050027379.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050033667.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050048644.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050047386.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221	"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway"
XP_050030584.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_050051156.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050041510.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050033713.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_050039297.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050048546.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050038669.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050033575.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050023165.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050041785.1	6	Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-264870;Reactome: R-HSA-111465;Reactome: R-HSA-111463;Reactome: R-HSA-111469	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Caspase-mediated cleavage of cytoskeletal proteins";"Apoptotic cleavage of cellular proteins";"SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response"
XP_050049817.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050038506.1	2	KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6	"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism"
XP_050050306.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050039389.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050042211.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050036758.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050041311.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050032314.1	6	Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-8950505;MetaCyc: PWY-6854;Reactome: R-HSA-8862803	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_050049664.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050025017.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_050027833.1	13	MetaCyc: PWY-6842;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;Reactome: R-HSA-196836	"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism"
XP_050039337.1	7	Reactome: R-HSA-1483191;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7782;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82	"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism"
XP_050049738.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050035499.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050045001.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050049095.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050042341.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_050046031.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_050044473.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050025696.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-139915	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria"
XP_050031029.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050042655.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050029424.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050050429.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050026421.1	4	Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-198693	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus"
XP_050043378.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050049591.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050025673.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050039398.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050052627.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-381042;Reactome: R-HSA-983170	"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_050023912.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050039472.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050033541.1	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
XP_050043445.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_050033362.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050052167.1	4	MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6	"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation";"Cysteine and methionine metabolism"
XP_050026352.1	16	MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.4;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5538;MetaCyc: PWY-5749	"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Itaconate degradation"
XP_050039528.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1"
XP_050031301.1	4	Reactome: R-HSA-977606;Reactome: R-HSA-375276;Reactome: R-HSA-174577;Reactome: R-HSA-418594	"Regulation of Complement cascade";"Peptide ligand-binding receptors";"Activation of C3 and C5";"G alpha (i) signalling events"
XP_050041247.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050043473.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050028687.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050025102.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050034248.1	17	Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176407	"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050037142.1	12	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I"
XP_050032814.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050034559.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_050045191.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050045755.1	4	Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_050044091.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050034544.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050044097.1	4	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050049839.1	7	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;MetaCyc: PWY-8004;Reactome: R-HSA-71336	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
XP_050043145.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050023509.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050049191.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_050042723.1	3	Reactome: R-HSA-5678771;Reactome: R-HSA-1989781;Reactome: R-HSA-382556	"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"PPARA activates gene expression";"ABC-family proteins mediated transport"
XP_050027599.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050026961.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050034110.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050049377.1	33	Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-180746	"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Mitotic Prometaphase";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein"
XP_050049349.1	7	Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050026016.1	4	KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004	"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I"
XP_050025395.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050031736.1	7	Reactome: R-HSA-9029569;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-3214815	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones"
XP_050029649.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050037445.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050031044.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050029988.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050023647.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050033242.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24	"p38MAPK events";"NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway"
XP_050049384.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_050026463.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050049468.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050032566.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050049007.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_050039627.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050038319.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050049297.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050035526.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050039261.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_050023915.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050041910.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050038706.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_050045957.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050039186.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050049357.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_050031914.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_050025383.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050025686.1	18	KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_050030572.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050052025.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050044774.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050049225.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050026350.1	7	KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043	"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_050048473.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050044542.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050031443.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-3214815	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones"
XP_050042346.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050045012.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050034964.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050044213.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-68962	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Activation of the pre-replicative complex"
XP_050044852.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050031330.1	9	Reactome: R-HSA-191859;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201	"snRNP Assembly";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050025012.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050028250.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050033245.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_050039207.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050041242.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050045916.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050027305.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_050028233.1	11	KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"p38MAPK events";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050040091.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050028333.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050027839.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050035920.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050039184.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050031801.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050035328.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_050048777.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_050027437.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050023466.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050039004.1	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_050037411.1	12	KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7817;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycogen synthesis";"Galactose metabolism";"Sucrose biosynthesis II"
XP_050035404.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050039108.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism"
XP_050044006.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050038317.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050051568.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_050036997.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050037034.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_050046257.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050033084.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_050034072.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_050026076.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050048520.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050039133.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050042926.1	5	Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_050036698.1	1	Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH2"
XP_050047475.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050036103.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
XP_050050323.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-909733	"Interferon gamma signaling";"Interferon alpha/beta signaling"
YP_010283870.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050048905.1	12	Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"G alpha (q) signalling events";"Human papillomavirus infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Rho GTPase cycle"
XP_050027434.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050026533.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359478;Reactome: R-HSA-71032;Reactome: R-HSA-3359475	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MUT causes methylmalonic aciduria mut type";"Propionyl-CoA catabolism";"Defective MMAA causes methylmalonic aciduria type cblA"
XP_050037742.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_050031827.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050029408.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_050022602.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-3214847;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-201722;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554	"Estrogen-dependent gene expression";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HATs acetylate histones";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Formation of the beta-catenin:TCF transactivating complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050026966.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050033832.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling"
XP_050048000.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050029861.1	16	Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128	"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling"
XP_050025745.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_050027433.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050042241.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8963901	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"VLDL assembly";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Scavenging by Class H Receptors";"VLDL clearance";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Chylomicron remodeling"
XP_050022976.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050050895.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050023897.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050038775.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050026977.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050024208.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050025319.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050036548.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050029906.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050049314.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050050950.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050032821.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050033390.1	18	KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;MetaCyc: PWY-8053	"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II"
XP_050041259.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050039279.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050038973.1	10	KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042	"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)"
XP_050049593.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050043190.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050051441.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050038212.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050044469.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128	"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling"
XP_050031370.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050047038.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050037464.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050030157.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050022910.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050036504.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050027157.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050027194.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_050029165.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050034684.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050036220.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050035537.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050051327.1	3	MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57	"Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism"
XP_050029644.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_050038361.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050041821.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050049409.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050026970.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_050037168.1	18	MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37	"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism"
XP_050030816.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374	"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_050049666.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050043333.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027640.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_050039707.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050037461.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_050041078.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050025229.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_050023177.1	23	Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_050042201.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050028235.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975	"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA"
XP_050047564.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
XP_050030169.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050049256.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_050034457.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.25;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-8853383	"Neutrophil degranulation";"HS-GAG degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Lysosomal oligosaccharide catabolism"
XP_050041044.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050050081.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050046077.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050026490.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050052245.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919	"Degradation of the extracellular matrix";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils"
XP_050032858.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-165159	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"mTOR signalling"
XP_050049903.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050022582.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050029834.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050025997.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050035829.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050024535.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050048526.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050023913.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050034857.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768	"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_050027514.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050025592.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050050017.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050047373.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;Reactome: R-HSA-6804757;Reactome: R-HSA-69541;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580	"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Degradation";"Stabilization of p53";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence"
XP_050034592.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050048975.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050033719.1	14	MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-5690	"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)"
XP_050048772.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050034749.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050048416.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_050043820.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_050028051.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050038813.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050030570.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050036627.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050052065.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050048459.1	17	MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;Reactome: R-HSA-163765;Reactome: R-HSA-200425;Reactome: R-HSA-196780	"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Biotin transport and metabolism"
XP_050030291.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050038799.1	10	Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695	"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_050047375.1	7	Reactome: R-HSA-6804757;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;Reactome: R-HSA-5689880;Reactome: R-HSA-69541;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585	"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"Ub-specific processing proteases";"Stabilization of p53";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence"
XP_050047841.1	5	MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781	"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)"
XP_050046904.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050024343.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050024250.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050031205.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050030850.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_050041373.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_050047040.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050028755.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050047377.1	8	Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;Reactome: R-HSA-71336;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791055;MetaCyc: PWY-5723;Reactome: R-HSA-163754	"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt";"Insulin effects increased synthesis of Xylulose-5-Phosphate"
XP_050036363.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_050048189.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_050041369.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050043549.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050039955.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-156581	"Ub-specific processing proteases";"Methylation"
XP_050037289.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050025135.1	2	Reactome: R-HSA-139853;Reactome: R-HSA-418346	"Elevation of cytosolic Ca2+ levels";"Platelet homeostasis"
XP_050050068.1	22	KEGG: 00500+5.3.1.9;MetaCyc: PWY-622;KEGG: 00010+5.3.1.9;MetaCyc: PWY-6142;MetaCyc: PWY-5054;MetaCyc: PWY-7385;MetaCyc: PWY-6981;MetaCyc: PWY-5514;Reactome: R-HSA-70263;KEGG: 00520+5.3.1.9;Reactome: R-HSA-5628897;Reactome: R-HSA-70171;MetaCyc: PWY-621;MetaCyc: PWY-6992;MetaCyc: PWY-5659;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5384;MetaCyc: PWY-7238;MetaCyc: PWY-8013;MetaCyc: PWY-3801;MetaCyc: PWY-7347;Reactome: R-HSA-6798695	"Starch and sucrose metabolism";"Starch biosynthesis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"D-sorbitol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Chitin biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"TP53 Regulates Metabolic Genes";"Glycolysis";"Sucrose degradation III (sucrose invertase)";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Pentose phosphate pathway";"Sucrose degradation IV (sucrose phosphorylase)";"Sucrose biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis III";"Neutrophil degranulation"
XP_050028206.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050030609.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050041848.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050033592.1	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
XP_050034846.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_050024180.1	9	Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955	"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050034840.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050049607.1	1	Reactome: R-HSA-5687128	"MAPK6/MAPK4 signaling"
XP_050036366.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050039353.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050045552.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921	"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation"
XP_050026080.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050029499.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones"
XP_050051443.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050032743.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050024325.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050037462.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_050036130.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050042670.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_050045342.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050040111.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050036866.1	4	KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism";"Selenocysteine synthesis"
XP_050027485.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050049608.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade"
XP_050048351.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050042682.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050048328.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050023605.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-9018519	"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression"
XP_050035667.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050039210.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050050510.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050035954.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050046186.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050045741.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_050045261.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_050037141.1	12	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism"
XP_050045167.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050039378.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_050025413.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061	"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I"
XP_050025746.1	3	Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response"
XP_050042094.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050047090.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050048208.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050052195.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination"
XP_050037704.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_050042210.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050033660.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050027480.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050036801.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050028106.1	3	KEGG: 00983+2.1.1.67;Reactome: R-HSA-5578995;Reactome: R-HSA-156581	"Drug metabolism - other enzymes";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Methylation"
XP_050041992.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050051837.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339;Reactome: R-HSA-879415	"Asparagine N-linked glycosylation";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling"
XP_050044580.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050038461.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_050041192.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_050044617.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050049292.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050047461.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050033246.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_050025841.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050038348.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050045704.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050045657.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050052301.1	33	KEGG: 00680+1.1.1.284;MetaCyc: PWY-6342;KEGG: 00626+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-5076;MetaCyc: PWY-6587;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-5082;MetaCyc: PWY-6802;KEGG: 00830+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-5480;MetaCyc: PWY-5486;KEGG: 00071+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00980+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-1801;MetaCyc: PWY-6313;Reactome: R-HSA-71384;MetaCyc: PWY-5079;MetaCyc: PWY-7396;MetaCyc: PWY-7798;MetaCyc: PWY-6871;MetaCyc: PWY-7118;MetaCyc: PWY-5057;MetaCyc: PWY-5751;MetaCyc: PWY-5078;KEGG: 00350+1.1.1.1	"Methane metabolism";"Noradrenaline and adrenaline degradation";"Naphthalene degradation";"Chloroalkane and chloroalkene degradation";"(S)-propane-1,2-diol degradation";"L-leucine degradation III";"Pyruvate fermentation to ethanol III";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to isobutanol (engineered)";"L-methionine degradation III";"Salidroside biosynthesis";"Retinol metabolism";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to ethanol II";"Fatty acid degradation";"Drug metabolism - cytochrome P450";"L-tryptophan degradation V (side chain pathway)";"Metabolism of xenobiotics by cytochrome P450";"Glycine, serine and threonine metabolism";"alpha-Linolenic acid metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Serotonin degradation";"Ethanol oxidation";"L-phenylalanine degradation III";"Butanol and isobutanol biosynthesis (engineered)";"Protein S-nitrosylation and denitrosylation";"3-methylbutanol biosynthesis (engineered)";"Chitin degradation to ethanol";"L-valine degradation II";"Phenylethanol biosynthesis";"L-isoleucine degradation II";"Tyrosine metabolism"
XP_050051043.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_050040115.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_050023860.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050026337.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050044616.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050023416.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_050037711.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_050047419.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050042080.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-1989781	"Circadian Clock";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression"
XP_050038339.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050037582.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050047122.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050045295.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050041328.1	5	Reactome: R-HSA-5635838;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5610787	"Activation of SMO";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state"
XP_050024419.1	4	KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_050023517.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050046518.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050050680.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892	"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation"
XP_050039588.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050043638.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050025568.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_050041542.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_050052646.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050044384.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050039465.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_050025840.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050044794.1	13	KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;MetaCyc: PWY-5133;MetaCyc: PWY-5132;KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672	"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Ethanol oxidation";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation"
XP_050042363.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_050039017.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050038830.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism"
XP_050051766.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis"
XP_050040149.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050029859.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459	"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050050921.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050050067.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050035213.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050044356.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050031200.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050030330.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050049727.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050042732.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_050048915.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050027416.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5981	"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III"
XP_050047372.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;Reactome: R-HSA-6804757;Reactome: R-HSA-2559585;Reactome: R-HSA-69541;Reactome: R-HSA-2559580	"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Degradation";"Oncogene Induced Senescence";"Stabilization of p53";"Oxidative Stress Induced Senescence"
XP_050033718.1	14	MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1	"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Butanoate metabolism"
XP_050039373.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_050031305.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050045934.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050037268.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050034332.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050029053.1	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050026845.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050048736.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050051182.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050046689.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_050026451.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050030717.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050050234.1	5	Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;Reactome: R-HSA-532668;MetaCyc: PWY-7919	"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)"
XP_050027568.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-156711;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Polo-like kinase mediated events";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050025573.1	3	KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K"
XP_050037017.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_050034905.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050046987.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050039085.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_050023818.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050049658.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050026397.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050031021.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_050037157.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_050051489.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050042083.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines"
XP_050043247.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050031585.1	5	Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-8948751	"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity"
XP_050040581.1	8	MetaCyc: PWY-7733;MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9	"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism"
XP_050050595.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050024364.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_050034644.1	52	Reactome: R-HSA-167161;Reactome: R-HSA-749476;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-5601884;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-1834949;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-77075	"HIV Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"PIWI-interacting RNA (piRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Cytosolic sensors of pathogen-associated DNA";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050048518.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_050040983.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050022569.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050037629.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050048792.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050026185.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050036213.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050049467.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050023643.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050037850.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050043043.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1"
XP_050048486.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050023549.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050050310.1	9	Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"tRNA modification in the nucleus and cytosol";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_050033555.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050030603.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050038756.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_050049888.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050044573.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050035781.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050023577.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-113418	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of the Early Elongation Complex"
XP_050038842.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050025706.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050041272.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_050044414.1	7	KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484	"Pentose phosphate pathway";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_050036559.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050031800.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050030054.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
XP_050052733.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050049690.1	5	Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-8856825;Reactome: R-HSA-917937;Reactome: R-HSA-8951664	"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport";"Neddylation"
XP_050030583.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_050029785.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_050030166.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_050039426.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_050052762.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402	"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex"
XP_050048791.1	1	KEGG: 00760+1.4.1.21	"Nicotinate and nicotinamide metabolism"
XP_050030696.1	6	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;Reactome: R-HSA-6787450;MetaCyc: PWY-7286;MetaCyc: PWY-6829	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)"
XP_050038505.1	2	KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6	"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism"
XP_050049722.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050048932.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050051807.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050041258.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050028399.1	10	KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04151+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153	"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"mTOR signaling pathway"
XP_050026258.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_050026119.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050045294.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050022795.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis"
XP_050029887.1	8	Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"HCMV Early Events";"SUMOylation of chromatin organization proteins"
XP_050043786.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049355.1	7	Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050022853.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050040898.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050052606.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050049712.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050030805.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050051954.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_050039853.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050029741.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050024898.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050023932.1	13	Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050048974.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050046880.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050045094.1	6	MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-4381;Reactome: R-HSA-196780	"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism"
XP_050037139.1	12	MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism"
XP_050047531.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050035685.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050038788.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050032594.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050023312.1	19	Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8964038	"Chylomicron remodeling";"Chylomicron assembly";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"VLDL clearance";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"VLDL assembly";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance"
XP_050045973.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_050046743.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050049520.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050052017.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050042395.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_050049141.1	9	MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883	"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II"
XP_050024833.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050033634.1	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
XP_050047336.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_050049883.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050050687.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244	"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation"
XP_050052314.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050039804.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_050028841.1	7	MetaCyc: PWY-5188;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-379716	"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation"
XP_050044393.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_050022874.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_050047117.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_050051162.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050045056.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050037007.1	11	MetaCyc: PWY-6549;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-7254;MetaCyc: PWY-7268	"L-glutamine biosynthesis III";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_050033724.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050046972.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_050049367.1	9	MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883	"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II"
XP_050049723.1	9	Reactome: R-HSA-1362277;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68689	"Transcription of E2F targets under negative control by DREAM complex";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex"
XP_050042097.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050048256.1	9	KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842	"Glutathione metabolism";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification II"
XP_050031483.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050040461.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050047733.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_050050173.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050026982.1	13	MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883	"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II"
XP_050038951.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049755.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050029940.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050026655.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050025342.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_050029596.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050043129.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1"
XP_050042317.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050051514.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050050517.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_050025834.1	4	MetaCyc: PWY-5651;MetaCyc: PWY-6309;Reactome: R-HSA-71240;KEGG: 00380+3.7.1.3	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Tryptophan metabolism"
XP_050048465.1	17	MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;Reactome: R-HSA-163765;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2	"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Fatty acid biosynthesis"
XP_050030299.1	5	Reactome: R-HSA-75896;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins"
XP_050045507.1	3	Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050044085.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050044729.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050048267.1	9	KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-156590	"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione conjugation"
XP_050036028.1	5	MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614	"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine catabolism";"Pyrimidine salvage"
XP_050026574.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_050047865.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_050031871.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050026484.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050051335.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756	"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation"
XP_050025729.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050042485.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050040294.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050025401.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050031738.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050035041.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050049304.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050050378.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050046782.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050040908.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050034725.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_050025374.1	19	Reactome: R-HSA-182971;Reactome: R-HSA-983231;Reactome: R-HSA-389359;Reactome: R-HSA-5625970;Reactome: R-HSA-5687128;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-3928662;Reactome: R-HSA-5663220;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-428543	"EGFR downregulation";"Factors involved in megakaryocyte development and platelet production";"CD28 dependent Vav1 pathway";"RHO GTPases activate KTN1";"MAPK6/MAPK4 signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"GPVI-mediated activation cascade";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"EPHB-mediated forward signaling";"RHO GTPases Activate Formins";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1"
XP_050038216.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050042727.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_050034534.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050025836.1	4	MetaCyc: PWY-5651;MetaCyc: PWY-6309;Reactome: R-HSA-71240;KEGG: 00380+3.7.1.3	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Tryptophan metabolism"
XP_050032477.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8941858	"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity"
XP_050036027.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050051770.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_050040735.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050043060.1	1	Reactome: R-HSA-71240	"Tryptophan catabolism"
XP_050035958.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050050501.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050044128.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050027586.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050043447.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050037397.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050022543.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050039854.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050049286.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_050051773.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_050042270.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050036557.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_050025932.1	4	Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9	"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism"
XP_050027983.1	4	KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III"
XP_050042081.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858	"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Estrogen-dependent gene expression";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines"
XP_050045770.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_050042263.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050024113.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670	"Glycosphingolipid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis"
XP_050035193.1	12	MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783	"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation"
XP_050036373.1	7	Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050041342.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050039371.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050030828.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050032742.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050041413.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050044083.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050032479.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050031253.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050044397.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_050027422.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-420499;Reactome: R-HSA-416476	"Neurexins and neuroligins";"Class C/3 (Metabotropic glutamate/pheromone receptors)";"G alpha (q) signalling events"
XP_050047534.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050031907.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_050045134.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050029589.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050051709.1	3	Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_050028030.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050047288.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050046004.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050049376.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_050030733.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050024189.1	52	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-5250924;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-72165	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"B-WICH complex positively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway"
XP_050043005.1	20	Reactome: R-HSA-75105;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00720+2.3.3.8;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5172;MetaCyc: PWY-5690;Reactome: R-HSA-1268020;KEGG: 00660+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7384	"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle II (plants and fungi)";"Mitochondrial protein import";"C5-Branched dibasic acid metabolism";"Neutrophil degranulation";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_050029838.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050043916.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050027557.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050051733.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-264870	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_050048066.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050046837.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-2173788	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"Downregulation of TGF-beta receptor signaling"
XP_050043822.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050031028.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050039563.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050023004.1	1	Reactome: R-HSA-156581	"Methylation"
XP_050051705.1	7	MetaCyc: PWY-7221;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205	"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_050044398.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_050048463.1	17	KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;Reactome: R-HSA-196780;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2	"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Biotin transport and metabolism";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Pyruvate metabolism"
XP_050039985.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050033583.1	9	MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227;MetaCyc: PWY-5265;Reactome: R-HSA-5633231;MetaCyc: PWY-6471;KEGG: 00513+2.4.1.141;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6385	"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)"
XP_050031038.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050022501.1	3	Reactome: R-HSA-5578995;KEGG: 00983+2.1.1.67;Reactome: R-HSA-156581	"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Drug metabolism - other enzymes";"Methylation"
XP_050038909.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050041498.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050047990.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_050035418.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050041352.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050023638.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050036161.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050045016.1	3	Reactome: R-HSA-8853659;Reactome: R-HSA-167044;Reactome: R-HSA-5673001	"RET signaling";"Signalling to RAS";"RAF/MAP kinase cascade"
XP_050050715.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050035003.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050041883.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670	"Glycosphingolipid metabolism";"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis"
XP_050046016.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050026442.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050051056.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050047031.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050044528.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation"
XP_050045043.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050031869.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050026507.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050025356.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050040507.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050041324.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_050022871.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050024814.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050025672.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050041847.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050029632.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050038337.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050039317.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050031586.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257	"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN"
XP_050027137.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050049714.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050047298.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050045361.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050031369.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050047312.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050038139.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050045058.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050051696.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050033553.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050025562.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050033013.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_050039135.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050040150.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050029294.1	19	Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-8876725;Reactome: R-HSA-975956;Reactome: R-HSA-3214858;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Protein methylation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"RMTs methylate histone arginines";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_050048643.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050049884.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050041794.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050047533.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050031591.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_050025263.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050039129.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_050052288.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050047091.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050042668.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_050032579.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050042043.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050048534.1	182	Reactome: R-HSA-3134975;Reactome: R-HSA-917937;Reactome: R-HSA-8939902;Reactome: R-HSA-6782135;Reactome: R-HSA-168638;Reactome: R-HSA-6781823;Reactome: R-HSA-2644606;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-174490;Reactome: R-HSA-110320;Reactome: R-HSA-1799339;Reactome: R-HSA-2173791;Reactome: R-HSA-162588;Reactome: R-HSA-5696395;Reactome: R-HSA-179409;Reactome: R-HSA-1169408;Reactome: R-HSA-3322077;Reactome: R-HSA-5610780;Reactome: R-HSA-8856828;Reactome: R-HSA-201681;Reactome: R-HSA-72702;Reactome: R-HSA-450321;Reactome: R-HSA-6783310;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-936440;Reactome: R-HSA-5654732;Reactome: R-HSA-174048;Reactome: R-HSA-2122947;Reactome: R-HSA-2173788;Reactome: R-HSA-5654727;Reactome: R-HSA-975110;Reactome: R-HSA-5696394;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-2565942;Reactome: R-HSA-5610783;Reactome: R-HSA-975163;Reactome: R-HSA-2122948;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5357905;Reactome: R-HSA-937041;Reactome: R-HSA-901032;Reactome: R-HSA-9033241;Reactome: R-HSA-1295596;Reactome: R-HSA-6804756;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5696400;Reactome: R-HSA-2173796;Reactome: R-HSA-8948751;Reactome: R-HSA-156902;Reactome: R-HSA-8875360;Reactome: R-HSA-5689877;Reactome: R-HSA-5684264;Reactome: R-HSA-5357956;Reactome: R-HSA-205043;Reactome: R-HSA-9014325;Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-6804757;Reactome: R-HSA-382556;Reactome: R-HSA-156827;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-182971;Reactome: R-HSA-5675221;Reactome: R-HSA-2559585;Reactome: R-HSA-72689;Reactome: R-HSA-4641257;Reactome: R-HSA-6791226;Reactome: R-HSA-5689603;Reactome: R-HSA-192823;Reactome: R-HSA-2173795;Reactome: R-HSA-1234176;Reactome: R-HSA-5685942;Reactome: R-HSA-450302;Reactome: R-HSA-8863795;Reactome: R-HSA-937042;Reactome: R-HSA-69541;Reactome: R-HSA-9633012;Reactome: R-HSA-4641263;Reactome: R-HSA-9613829;Reactome: R-HSA-917729;Reactome: R-HSA-6804760;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-75815;Reactome: R-HSA-5693565;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-977225;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5696397;Reactome: R-HSA-9013507;Reactome: R-HSA-912631;Reactome: R-HSA-937072;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-72706;Reactome: R-HSA-5693607;Reactome: R-HSA-8876493;Reactome: R-HSA-9010553;Reactome: R-HSA-9645460;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-69231;Reactome: R-HSA-9020702;Reactome: R-HSA-1236382;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-5668541;Reactome: R-HSA-5656169;Reactome: R-HSA-209543;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-400253;Reactome: R-HSA-1253288;Reactome: R-HSA-5676590;Reactome: R-HSA-3785653;Reactome: R-HSA-9615710;Reactome: R-HSA-975144;Reactome: R-HSA-975956;Reactome: R-HSA-5654733;Reactome: R-HSA-8941858;Reactome: R-HSA-445989;Reactome: R-HSA-209560;Reactome: R-HSA-2691232;Reactome: R-HSA-5654726;Reactome: R-HSA-168928;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-9637628;Reactome: R-HSA-5358346;Reactome: R-HSA-175474;Reactome: R-HSA-5205685;Reactome: R-HSA-72764;Reactome: R-HSA-532668;Reactome: R-HSA-72695;Reactome: R-HSA-9646399;Reactome: R-HSA-2408557;Reactome: R-HSA-8849469;Reactome: R-HSA-5689896;Reactome: R-HSA-2559580;Reactome: R-HSA-936964;Reactome: R-HSA-8939236;Reactome: R-HSA-1358803;Reactome: R-HSA-2979096;Reactome: R-HSA-5678895;Reactome: R-HSA-6781827;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-9013973;Reactome: R-HSA-8866652;Reactome: R-HSA-5658442;Reactome: R-HSA-5675482;Reactome: R-HSA-5689901;Reactome: R-HSA-8856825;Reactome: R-HSA-3769402;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-6782210;Reactome: R-HSA-2672351;Reactome: R-HSA-168927;Reactome: R-HSA-180585;Reactome: R-HSA-937039;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050	"Regulation of innate immune responses to cytosolic DNA";"Iron uptake and transport";"Regulation of RUNX2 expression and activity";"Dual incision in TC-NER";"NOD1/2 Signaling Pathway";"Formation of TC-NER Pre-Incision Complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Membrane binding and targetting of GAG proteins";"Translesion Synthesis by POLH";"SRP-dependent cotranslational protein targeting to membrane";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Budding and maturation of HIV virion";"Formation of Incision Complex in GG-NER";"APC-Cdc20 mediated degradation of Nek2A";"ISG15 antiviral mechanism";"Glycogen synthesis";"Degradation of GLI1 by the proteasome";"Clathrin-mediated endocytosis";"TCF dependent signaling in response to WNT";"Ribosomal scanning and start codon recognition";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Fanconi Anemia Pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulators of DDX58/IFIH1 signaling";"Negative regulation of FGFR3 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"NOTCH1 Intracellular Domain Regulates Transcription";"Downregulation of TGF-beta receptor signaling";"Negative regulation of FGFR2 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DNA Damage Recognition in GG-NER";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI2 by the proteasome";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Activated NOTCH1 Transmits Signal to the Nucleus";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of TNFR1 signaling";"IKK complex recruitment mediated by RIP1";"ER Quality Control Compartment (ERQC)";"Peroxisomal protein import";"Spry regulation of FGF signaling";"Regulation of TP53 Activity through Phosphorylation";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Dual Incision in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of PTEN stability and activity";"Peptide chain elongation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Josephin domain DUBs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TNFR1-induced NFkappaB signaling pathway";"NRIF signals cell death from the nucleus";"TICAM1,TRAF6-dependent induction of TAK1 complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"Regulation of TP53 Degradation";"ABC-family proteins mediated transport";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"EGFR downregulation";"Negative regulation of MAPK pathway";"Oncogene Induced Senescence";"Formation of a pool of free 40S subunits";"Degradation of AXIN";"Major pathway of rRNA processing in the nucleolus and cytosol";"UCH proteinases";"Viral mRNA Translation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HDR through Homologous Recombination (HRR)";"activated TAK1 mediates p38 MAPK activation";"Downregulation of ERBB2 signaling";"IRAK2 mediated activation of TAK1 complex";"Stabilization of p53";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of FZD by ubiquitination";"Chaperone Mediated Autophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of TP53 Activity through Methylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Ubiquitin-dependent degradation of Cyclin D";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Amyloid fiber formation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of signaling by CBL";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Processing of DNA double-strand break ends";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of expression of SLITs and ROBOs";"Alpha-protein kinase 1 signaling pathway";"ER-Phagosome pathway";"Neddylation";"Cyclin D associated events in G1";"Interleukin-1 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"TNFR2 non-canonical NF-kB pathway";"Termination of translesion DNA synthesis";"p75NTR recruits signalling complexes";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Circadian Clock";"Downregulation of ERBB4 signaling";"NIK-->noncanonical NF-kB signaling";"Myoclonic epilepsy of Lafora";"Late endosomal microautophagy";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Negative regulation of FGFR4 signaling";"Regulation of RUNX3 expression and activity";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NF-kB is activated and signals survival";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Negative regulation of FGFR1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Regulation of PTEN localization";"Ub-specific processing proteases";"Modulation by Mtb of host immune system";"Hedgehog ligand biogenesis";"Assembly Of The HIV Virion";"Pink/Parkin Mediated Mitophagy";"Eukaryotic Translation Termination";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of the ternary complex, and subsequently, the 43S complex";"Aggrephagy";"Selenocysteine synthesis";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Ovarian tumor domain proteases";"Oxidative Stress Induced Senescence";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of ERBB2:ERBB3 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Defective CFTR causes cystic fibrosis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"TICAM1-dependent activation of IRF3/IRF7";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of RAS by GAPs";"Regulation of necroptotic cell death";"Metalloprotease DUBs";"Cargo recognition for clathrin-mediated endocytosis";"Deactivation of the beta-catenin transactivating complex";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Stimuli-sensing channels";"TICAM1, RIP1-mediated IKK complex recruitment";"Vif-mediated degradation of APOBEC3G";"IRAK1 recruits IKK complex";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_050040623.1	30	Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-9604323;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2894862;Reactome: R-HSA-69231;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1170546;Reactome: R-HSA-5610780;Reactome: R-HSA-400253;Reactome: R-HSA-187577;Reactome: R-HSA-5610783	"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"Negative regulation of NOTCH4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Vpu mediated degradation of CD4";"Iron uptake and transport";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Cyclin D associated events in G1";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Prolactin receptor signaling";"Degradation of GLI1 by the proteasome";"Circadian Clock";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome"
XP_050039705.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050042930.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050038566.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050051744.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050031484.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050043918.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050034306.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050048417.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394	"UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER"
XP_050045983.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050035735.1	17	MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37	"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms"
XP_050027937.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050036143.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_050031786.1	56	Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154	"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin"
XP_050045260.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_050051732.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-264870;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins"
XP_050022993.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050048158.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050050066.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_050034061.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050036448.1	5	KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661	"Propanoate metabolism";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_050038594.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050051483.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050047641.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050049432.1	3	Reactome: R-HSA-532668;Reactome: R-HSA-901032;MetaCyc: PWY-7511	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination"
XP_050043826.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050048125.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_050051808.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050051098.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-450408	"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_050040677.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050044438.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050038815.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050029071.1	10	MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001	"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050023639.1	7	KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10	"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_050026114.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050043008.1	3	Reactome: R-HSA-156581;Reactome: R-HSA-5578995;KEGG: 00983+2.1.1.67	"Methylation";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Drug metabolism - other enzymes"
XP_050035787.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050049772.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050047656.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-203927	"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis"
XP_050048291.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050028883.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050047604.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_050033969.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050046299.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050035889.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692	"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity"
XP_050039698.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis"
XP_050041737.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050033799.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis"
XP_050045340.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050031442.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050032578.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050041184.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050041012.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_050038146.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_050038137.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050034001.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"mTORC1-mediated signalling";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050036053.1	3	MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2	"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_050050490.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050022941.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050040361.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050046746.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050029425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050024464.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050041696.1	10	MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10	"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation"
XP_050039341.1	13	Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-216083;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332	"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"ECM proteoglycans";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Integrin cell surface interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_050048067.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050028191.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823	"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation"
XP_050023896.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050050337.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050044690.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050042654.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050031109.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050023317.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050026168.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050049124.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780	"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome"
XP_050040730.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050039871.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050047473.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050051598.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050049373.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050038032.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050038778.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050041850.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050043547.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050022958.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_050038620.1	9	MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2	"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism"
XP_050045926.1	3	Reactome: R-HSA-173623;Reactome: R-HSA-166663;Reactome: R-HSA-977606	"Classical antibody-mediated complement activation";"Initial triggering of complement";"Regulation of Complement cascade"
XP_050043919.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050029508.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050039797.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050043294.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2"
XP_050048431.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050045028.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050034739.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_050030428.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_050040991.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050047387.1	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway"
XP_050026492.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050030761.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050037527.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050022808.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050050686.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948	"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants"
XP_050023274.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050045113.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050038667.1	4	MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050031111.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050023199.1	7	KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14	"Purine metabolism";"Pyrimidine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes"
XP_050052205.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_050027700.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_050045667.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050023720.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050032944.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050052631.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050045170.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760	"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation"
XP_050049803.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050036621.1	5	Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_050044998.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050050872.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050047573.1	3	MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050042110.1	24	Reactome: R-HSA-111931;Reactome: R-HSA-9010642;Reactome: R-HSA-180024;Reactome: R-HSA-5610783;Reactome: R-HSA-4420097;Reactome: R-HSA-422356;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780;Reactome: R-HSA-163358;Reactome: R-HSA-381676;Reactome: R-HSA-9634600;Reactome: R-HSA-5610785;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-392517;Reactome: R-HSA-163615;Reactome: R-HSA-163560;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5621575;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-8853659;Reactome: R-HSA-8963896;Reactome: R-HSA-5687128	"PKA-mediated phosphorylation of CREB";"ROBO receptors bind AKAP5";"DARPP-32 events";"Degradation of GLI2 by the proteasome";"VEGFA-VEGFR2 Pathway";"Regulation of insulin secretion";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome";"PKA-mediated phosphorylation of key metabolic factors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"GLI3 is processed to GLI3R by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Rap1 signalling";"PKA activation";"Triglyceride catabolism";"mTOR signaling pathway";"CD209 (DC-SIGN) signaling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"RET signaling";"HDL assembly";"MAPK6/MAPK4 signaling"
XP_050034558.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_050046554.1	17	MetaCyc: PWY-6608;MetaCyc: PWY-5532;MetaCyc: PWY-6620;MetaCyc: PWY-7179;KEGG: 00230+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-6644;MetaCyc: PWY-4202;Reactome: R-HSA-74259;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;Reactome: R-HSA-74217;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609	"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Purine catabolism";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Purine salvage";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Adenine and adenosine salvage III"
XP_050048470.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050036461.1	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Circadian Clock";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling"
XP_050041140.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399	"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_050034639.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050045358.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050028196.1	9	MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II"
XP_050044571.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050052687.1	26	Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-4615885;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-69183;Reactome: R-HSA-5685942;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-8866654;Reactome: R-HSA-69091;Reactome: R-HSA-174417;Reactome: R-HSA-6782210	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"SUMOylation of DNA replication proteins";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Processive synthesis on the lagging strand";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"E3 ubiquitin ligases ubiquitinate target proteins";"Polymerase switching";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050029774.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_050039301.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_050049143.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050025320.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050024167.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050045695.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050041313.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050032121.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-381676	"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"PKA activation";"Hedgehog 'off' state";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_050028889.1	6	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_050024345.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_050046838.1	14	Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-165054;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-69273	"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"Rev-mediated nuclear export of HIV RNA";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050034359.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_050048244.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050031348.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050050611.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050026500.1	5	Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7185;MetaCyc: PWY-7176	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis"
XP_050023628.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050024696.1	6	Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Ub-specific processing proteases";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_050037483.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_050024746.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050046197.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050043144.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050035455.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050029082.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_050031244.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050052603.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050050590.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537	"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_050035830.1	1	Reactome: R-HSA-8963693	"Aspartate and asparagine metabolism"
XP_050024588.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050044703.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050023541.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050050343.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050043114.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050051590.1	5	Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3"
XP_050040874.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050025482.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050044424.1	24	Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-418592	"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"G alpha (z) signalling events";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1"
XP_050030022.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050025931.1	4	KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247	"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids"
XP_050030791.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050040334.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050044795.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050038848.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050041822.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050046404.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050032545.1	3	Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269	"Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
XP_050024463.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050029443.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050051233.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050026046.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398	"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Ca2+ pathway"
XP_050031040.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050050525.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050044527.1	10	Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-163680	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity"
XP_050052565.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
YP_010283874.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050026320.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050045467.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050038644.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_050024240.1	5	Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-977225	"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Aggrephagy";"Amyloid fiber formation"
XP_050045264.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050040436.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050036755.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050032553.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_050031209.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050036614.1	5	MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis"
XP_050030675.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_050030709.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050045334.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050052617.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050029440.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050045005.1	11	Reactome: R-HSA-168138;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;MetaCyc: PWY-6352	"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"Macroautophagy";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"3-phosphoinositide biosynthesis"
XP_050034982.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050044996.1	2	Reactome: R-HSA-4549349;Reactome: R-HSA-446193	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050024504.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050037757.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050052521.1	4	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation";"Pyrophosphate hydrolysis"
XP_050028887.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050048060.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050031674.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050048460.1	17	KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;MetaCyc: PWY-6679;Reactome: R-HSA-196780;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2	"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism"
XP_050040092.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050039446.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050026535.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050023713.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050047359.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_050035555.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_050040650.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050028850.1	6	KEGG: 00900+2.7.1.36;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273	"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis"
XP_050032988.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050029540.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050026626.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050029507.1	6	Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;Reactome: R-HSA-1483166;MetaCyc: PWY-5668;MetaCyc: PWY-5269	"Synthesis of PG";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II"
XP_050031019.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_050030648.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050046026.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_050036464.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050051067.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050046752.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050037255.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050022952.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050048017.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050046595.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050023808.1	7	KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050034030.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050049845.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_050027556.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050025704.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050026342.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050050099.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050027755.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050049875.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050027602.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050025347.1	20	Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;Reactome: R-HSA-8943724;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972	"mTORC1-mediated signalling";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"HSF1-dependent transactivation";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"Regulation of PTEN gene transcription";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Relaxin signaling pathway";"PIP3 activates AKT signaling";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050044153.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050027497.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis"
XP_050030318.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050024031.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050047319.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050049709.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050030800.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050050834.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050043614.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050031594.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050035971.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050044948.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050034954.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050032082.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050038643.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_050051802.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050033609.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050039702.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_050041624.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050029102.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_050050902.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050027992.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050045753.1	4	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-532668	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050040680.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_050044750.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_050041798.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050033584.1	9	Reactome: R-HSA-5633231;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6385;KEGG: 00513+2.4.1.141;Reactome: R-HSA-446193;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis"
XP_050035176.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_050042347.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050026538.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050029894.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_050033759.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050046055.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050047532.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050037033.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_050025705.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050041472.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050024785.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050049414.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050048405.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050033477.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050048916.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050033456.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050045374.1	3	Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151	"eNOS activation";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_050042358.1	22	Reactome: R-HSA-75876;MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7606;MetaCyc: PWY-6433;MetaCyc: PWY-6958;MetaCyc: PWY-7724;MetaCyc: PWY-7726;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7053;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;KEGG: 00062+4.2.1.134	"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_050040510.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050025947.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050038350.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949664	"Mitochondrial protein import";"Processing of SMDT1"
XP_050044401.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_050023499.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_050043789.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050052549.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050031678.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050043647.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050035188.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_050025375.1	19	Reactome: R-HSA-428543;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-3928662;Reactome: R-HSA-5626467;Reactome: R-HSA-2029482;Reactome: R-HSA-8964616;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-525793;Reactome: R-HSA-8950505;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-983231	"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"EPHB-mediated forward signaling";"RHO GTPases activate IQGAPs";"Regulation of actin dynamics for phagocytic cup formation";"G beta:gamma signalling through CDC42";"Rho GTPase cycle";"GPVI-mediated activation cascade";"Myogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"CD28 dependent Vav1 pathway";"EGFR downregulation";"Factors involved in megakaryocyte development and platelet production"
XP_050052577.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050025600.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050030055.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism"
XP_050029431.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050042621.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050025016.1	4	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_050047808.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050033532.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050028353.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_050025394.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050050788.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050034628.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050033243.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24	"p38MAPK events";"NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway"
XP_050037857.1	14	MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7589	"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_050043115.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050049223.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050025837.1	4	MetaCyc: PWY-5651;MetaCyc: PWY-6309;Reactome: R-HSA-71240;KEGG: 00380+3.7.1.3	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Tryptophan metabolism"
XP_050029364.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050041693.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-606279	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050042238.1	7	MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-5316;Reactome: R-HSA-196807;KEGG: 00760+6.3.4.21;KEGG: 00760+2.4.2.19;MetaCyc: PWY-7342	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotine biosynthesis";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Superpathway of nicotine biosynthesis"
XP_050040304.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050039138.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050039334.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782;MetaCyc: PWY-3385;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-7886;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC"
XP_050032649.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050052632.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050044080.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050031153.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_050045266.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050028326.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_050034408.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050026625.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050034442.1	4	KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Selenoamino acid metabolism"
XP_050037004.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050051473.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_050051702.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050039785.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050041683.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050039089.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050046002.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_050023768.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_050026550.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050027552.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050050908.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050035482.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-6783310;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Fanconi Anemia Pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050044049.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050035778.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050029427.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050044887.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_050027710.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050030411.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_050052566.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050051693.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050033250.1	12	MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-6708	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_050049544.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050033661.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050032079.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050052719.1	14	MetaCyc: PWY-6936;MetaCyc: PWY-601;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;Reactome: R-HSA-8964208;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;MetaCyc: PWY-2821;Reactome: R-HSA-8964539;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-6842	"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Phenylalanine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glutamate and glutamine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Glutathione-mediated detoxification II"
XP_050031637.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050030921.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050032563.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050034931.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050024805.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842	"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_050036612.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050040935.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050034317.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050050217.1	8	Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"ATP biosynthesis";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Photosynthesis";"ROS and RNS production in phagocytes"
XP_050034732.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_050048775.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-141444	"Platelet sensitization by LDL";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050022996.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050022911.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214	"Betanidin degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_050046050.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050023250.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050030846.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_050033399.1	4	Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20	"Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism"
XP_050039867.1	5	KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_050026035.1	10	Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_050034279.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050031049.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050045969.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050024650.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_050029844.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050041990.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050032389.1	2	MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050026446.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050030381.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050036486.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050036502.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050032577.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050023992.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050033540.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050038323.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050036430.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-141444	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050034245.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_050036828.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050050256.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050047701.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050025941.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852	"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy"
XP_050029083.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050034243.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_050026050.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_050050029.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_050034065.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050051569.1	17	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050025607.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050044800.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050035466.1	4	MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_050043912.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050022515.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050045540.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050047671.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_050036919.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050045561.1	6	Reactome: R-HSA-71240;MetaCyc: PWY-5647;MetaCyc: PWY-6309;MetaCyc: PWY-6505;MetaCyc: PWY-5651;KEGG: 00380+1.13.11.6	"Tryptophan catabolism";"2-nitrobenzoate degradation I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation XII (Geobacillus)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism"
XP_050030062.1	5	Reactome: R-HSA-9627069;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism";"Formation of apoptosome"
XP_050038939.1	18	MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7176;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism"
XP_050038790.1	7	Reactome: R-HSA-198323;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214	"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs"
XP_050030784.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050044556.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050042401.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress"
XP_050040044.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050031351.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050051361.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050026033.1	3	KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050029891.1	8	Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins";"HCMV Early Events"
XP_050027343.1	8	KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_050022995.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050050516.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050027419.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_050032053.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050030063.1	5	Reactome: R-HSA-9627069;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism";"Formation of apoptosome"
XP_050040624.1	30	Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-917937;Reactome: R-HSA-9020702;Reactome: R-HSA-2644607;Reactome: R-HSA-2565942;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1170546;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-5610783;Reactome: R-HSA-2894862;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-69231;Reactome: R-HSA-2871837	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Iron uptake and transport";"Interleukin-1 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of PLK1 Activity at G2/M Transition";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Prolactin receptor signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation"
XP_050047655.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_050039593.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050038833.1	5	KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_050048807.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050048305.1	4	KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_050037484.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_050027741.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes"
XP_050038839.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050028265.1	4	KEGG: 00983+2.3.1.5;KEGG: 00232+2.3.1.5;Reactome: R-HSA-156582;KEGG: 00633+2.3.1.5	"Drug metabolism - other enzymes";"Caffeine metabolism";"Acetylation";"Nitrotoluene degradation"
XP_050042922.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050051515.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050028102.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050037838.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050046083.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050037627.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050027424.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050031035.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Ub-specific processing proteases"
XP_050037399.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780	"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome"
XP_050025072.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_050049630.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050040107.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050048738.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050029826.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-8943723	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation"
XP_050026098.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050027282.1	10	Reactome: R-HSA-499943;Reactome: R-HSA-69205;MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7199;MetaCyc: PWY-7184	"Interconversion of nucleotide di- and triphosphates";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"One carbon pool by folate";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_050049253.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050025492.1	10	MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001	"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050046817.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050051357.1	26	Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-389960;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs"
XP_050052715.1	14	KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6936;MetaCyc: PWY-601;MetaCyc: PWY-2821;MetaCyc: PWY-7901;Reactome: R-HSA-8964539;Reactome: R-HSA-8964208;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842	"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Glutamate and glutamine metabolism";"Phenylalanine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II"
XP_050026260.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050052558.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050030810.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167242	"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_050037446.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050036365.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050033613.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050035709.1	3	KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383	"Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism"
XP_050051719.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_050025877.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050029643.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050023463.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050039893.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050051843.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050040155.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050049763.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050052659.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050027592.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050032785.1	4	MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26	"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_050039527.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_050040028.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_050031032.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050044660.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050034643.1	52	Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-167161;Reactome: R-HSA-749476;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-5250924;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73780;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-5578749	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"B-WICH complex positively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase III Chain Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcriptional regulation by small RNAs"
XP_050025670.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050030734.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050047553.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-1268020;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-111457	"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Mitochondrial protein import";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria"
XP_050022818.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050050546.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050035528.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050029430.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050048896.1	11	Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050023714.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-167290	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation"
XP_050031195.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050030509.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_050025983.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050040997.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050033422.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050032851.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050030766.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050043470.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_050042988.1	10	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;Reactome: R-HSA-201722	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"HATs acetylate histones";"Thermogenesis";"PI3K-Akt signaling pathway";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Formation of the beta-catenin:TCF transactivating complex"
XP_050029740.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050023136.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050030629.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_050024346.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_050032740.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050041270.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_050037497.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050050653.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050025379.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050037610.1	5	Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168	"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_050024989.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050045013.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050034157.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_050035212.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050051362.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050026696.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050050104.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050025499.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050034887.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050042215.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_050048211.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050046952.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050039300.1	4	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
XP_050052060.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050043138.1	14	Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-112382	"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex"
XP_050044203.1	4	Reactome: R-HSA-4570464;Reactome: R-HSA-72163;Reactome: R-HSA-9610379;Reactome: R-HSA-72203	"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway";"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050046839.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-5626467	"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs"
XP_050039997.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_050046969.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050025688.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050025131.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050051839.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050039041.1	4	Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050037205.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050025461.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842	"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II"
XP_050045831.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050045172.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050051195.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050040460.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050042122.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_050027513.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050022586.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050037466.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050030286.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism"
XP_050051140.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050027496.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_050034780.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050029601.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050045129.1	6	KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-5663	"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_050039580.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050048009.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_050036253.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-901032	"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)"
XP_050032249.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050051597.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors"
XP_050048467.1	17	MetaCyc: PWY-6679;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;Reactome: R-HSA-163765;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Jadomycin biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
XP_050051490.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050049606.1	1	Reactome: R-HSA-5687128	"MAPK6/MAPK4 signaling"
XP_050026794.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050038843.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050033512.1	5	KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937	"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport"
XP_050035183.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_050045530.1	6	Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_050028645.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050026240.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050035581.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_050030569.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050044095.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_050041823.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050048943.1	5	MetaCyc: PWY-4983;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Arginine and proline metabolism"
XP_050026024.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050049680.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050030514.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_050049116.1	9	MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-6142;Reactome: R-HSA-1475029	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide"
XP_050042264.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050037064.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050048212.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050039562.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050030793.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050052808.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_050030466.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050024145.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050046542.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050043540.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_050045223.1	8	MetaCyc: PWY-4983;MetaCyc: PWY-4984;MetaCyc: PWY-7400;KEGG: 00220+4.3.2.1;KEGG: 00250+4.3.2.1;MetaCyc: PWY-5154;Reactome: R-HSA-70635;MetaCyc: PWY-5	"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Canavanine biosynthesis"
XP_050044027.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-5682294	"ABC transporters in lipid homeostasis";"Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B"
XP_050032107.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050049924.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050044992.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050042569.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050042828.1	3	Reactome: R-HSA-5678771;Reactome: R-HSA-1989781;Reactome: R-HSA-382556	"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"PPARA activates gene expression";"ABC-family proteins mediated transport"
XP_050045007.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050033345.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050032690.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050026779.1	4	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_050048638.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050041929.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050039992.1	6	KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21	"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_050030796.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050039626.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050035705.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050041139.1	5	Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-5083630	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3"
XP_050022490.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050044997.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050044100.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050027438.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050047821.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050050549.1	18	MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE"
XP_050031596.1	4	Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281	"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050045397.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050024739.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050051846.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_050027252.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050024523.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050025835.1	4	MetaCyc: PWY-6309;MetaCyc: PWY-5651;KEGG: 00380+3.7.1.3;Reactome: R-HSA-71240	"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"Tryptophan catabolism"
XP_050035956.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050035890.1	10	Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA"
XP_050028689.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050049874.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050042592.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050035378.1	33	Reactome: R-HSA-75955;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-69231;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-69202;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-69273;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"Cyclin D associated events in G1";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050052064.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050042247.1	7	MetaCyc: PWY-5381;MetaCyc: PWY-5316;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.4.21;KEGG: 00760+2.4.2.19;MetaCyc: PWY-7342	"Pyridine nucleotide cycling (plants)";"Nicotine biosynthesis";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Superpathway of nicotine biosynthesis"
XP_050049254.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050051751.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050032565.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050023475.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-180910	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs"
XP_050023842.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050049115.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1	"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism"
XP_050050861.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_050038404.1	7	KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263	"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis"
XP_050023190.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050048711.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050042436.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_050040365.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050037107.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050032833.1	5	MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_050045194.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050023266.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_050049651.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050049192.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050036857.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050052133.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050043078.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_050038928.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_050030920.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050034066.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050042260.1	19	Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046	"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"VLDL assembly";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Chylomicron assembly";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"VLDL clearance"
XP_050052483.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050040158.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation"
XP_050049698.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050027216.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050038116.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_050033447.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050024516.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050030575.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050040458.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050023298.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050038514.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050051314.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_050024845.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_050033453.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050029515.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA"
XP_050037526.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050024494.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050030480.1	13	KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2022857	"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Keratan sulfate degradation"
XP_050036239.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050027729.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-171319;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_050042041.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050048906.1	12	Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04926+2.7.11.1	"G alpha (q) signalling events";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Rho GTPase cycle";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"DCC mediated attractive signaling";"Relaxin signaling pathway"
XP_050041239.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050024957.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_050030729.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050025338.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050051950.1	11	KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2	"Arginine biosynthesis";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism"
XP_050044476.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813	"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids"
XP_050050016.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050040211.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_050049381.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050037790.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050044051.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050037854.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667	"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I"
XP_050033770.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050037140.1	12	MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_050049378.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050047786.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050033574.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050043659.1	12	Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_050029901.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050045406.1	2	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_050036848.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_050031818.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism"
XP_050026855.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050036368.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050041341.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050023241.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_050034460.1	3	Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25	"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Other glycan degradation"
XP_050049983.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050025414.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050031535.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape"
XP_050048787.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050037926.1	17	MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)"
XP_050024749.1	57	Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590	"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling"
XP_050048806.1	10	MetaCyc: PWY-6365;MetaCyc: PWY-6366;KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855204;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;MetaCyc: PWY-6554;Reactome: R-HSA-983231;MetaCyc: PWY-4661	"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_050052063.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050025371.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050036129.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_050038318.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050028486.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050044784.1	11	Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986	"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2"
XP_050036188.1	4	Reactome: R-HSA-3359462;Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463	"Defective AMN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1"
XP_050052126.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050032661.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050026319.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050040259.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050034972.1	5	KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050036704.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050025910.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050026032.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050049155.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050039082.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050049885.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050049982.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050044478.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761	"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_050027175.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050026416.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050030014.1	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050027141.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050050753.1	9	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_050043463.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050031479.1	56	Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-211733	"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_050047080.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050026443.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050048505.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050041001.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050035523.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050045015.1	3	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001;Reactome: R-HSA-167044	"RET signaling";"RAF/MAP kinase cascade";"Signalling to RAS"
XP_050031113.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050043305.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050040206.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050040981.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050040463.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050024653.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_050027502.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050030253.1	5	Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;Reactome: R-HSA-9627069	"Formation of apoptosome";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity"
XP_050027444.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050026288.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050047997.1	22	Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257	"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion"
XP_050033500.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050050238.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050029822.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_050046583.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050050200.1	4	Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050050471.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PG";"Role of phospholipids in phagocytosis"
XP_050023046.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050044995.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050034927.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050024313.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_050048977.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050051592.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)"
XP_050050232.1	5	Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;Reactome: R-HSA-532668;MetaCyc: PWY-7919	"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)"
XP_050047163.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050031022.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_050042198.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050051309.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050049219.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050023644.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050041635.1	40	KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-7401;MetaCyc: PWY-7779;MetaCyc: PWY-6944;MetaCyc: PWY-7654;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7726;MetaCyc: PWY-5109;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-5177;MetaCyc: PWY-6863;MetaCyc: PWY-6883;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-1361;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5138;MetaCyc: PWY-6946;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17	"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Phenylalanine metabolism";"Pyruvate fermentation to butanol I";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl tert-butyl ether degradation";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Caprolactam degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glutaryl-coa degradation";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"beta-Alanine metabolism";"2-methylpropene degradation";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Toluene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Geraniol degradation";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid salvage";"Lysine degradation";"Fatty acid elongation";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"Aminobenzoate degradation"
XP_050032549.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050047221.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050039455.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050032502.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050037418.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050033754.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050025077.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050031707.1	10	Reactome: R-HSA-9022535;Reactome: R-HSA-8986944;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-9022702;Reactome: R-HSA-9022707;Reactome: R-HSA-9022699;Reactome: R-HSA-9022927;Reactome: R-HSA-9022534	"Loss of phosphorylation of MECP2 at T308";"Transcriptional Regulation by MECP2";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates transcription factors";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of genes involved in GABA signaling";"Loss of MECP2 binding ability to 5hmC-DNA"
XP_050037523.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050034828.1	9	Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323	"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol"
XP_050047658.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_050032550.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050042018.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050035135.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_050035381.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_050047364.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050029421.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050051718.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_050050937.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050035465.1	4	KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801	"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion"
XP_050049092.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050050699.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948	"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF activation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling downstream of RAS mutants"
XP_050038334.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050029057.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826	"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis"
XP_050042178.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807	"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_050031496.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050030710.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050024743.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050037013.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050025393.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050040979.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050027711.1	4	MetaCyc: PWY-5028;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5030;Reactome: R-HSA-70921	"L-histidine degradation II";"Histidine metabolism";"L-histidine degradation III";"Histidine catabolism"
XP_050040343.1	6	KEGG: 00562+3.1.3.64;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660517;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050044456.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050044581.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050050909.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050051491.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_050046507.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050042726.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050026286.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050045547.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050045225.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555	"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events"
XP_050046980.1	5	Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20	"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis"
XP_050031304.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050046840.1	6	Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275	"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation"
XP_050037094.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition"
XP_050034507.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295	"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"MHC class II antigen presentation"
XP_050034241.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_050022938.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-202424	"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling"
XP_050032600.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050046770.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050047785.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050037290.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050034367.1	14	KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-1622;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-5497;MetaCyc: PWY-2161	"Methane metabolism";"Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"One carbon pool by folate";"Photorespiration ";"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Folate transformations I";"Cyanoamino acid metabolism";"Glycine betaine degradation II (mammalian)";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation"
XP_050034760.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050043791.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050030707.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
XP_050042361.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050024842.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050039005.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_050026721.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050032521.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050045030.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_050040037.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_050033909.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050032364.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050036094.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050049003.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050030742.1	6	MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation"
XP_050048816.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_050052742.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050044472.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050022514.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050028550.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050051436.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050051240.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050050276.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-425986	"Stimuli-sensing channels";"Sodium/Proton exchangers"
XP_050052551.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050025588.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050045359.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050049919.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050023256.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050023271.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050049801.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050027285.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050050793.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_050044585.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050039209.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050045575.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050044842.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050025457.1	10	MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis"
XP_050030084.1	5	Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
XP_050030429.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050031861.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination"
XP_050026009.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050025874.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050030913.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050050818.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050041690.1	2	MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050042040.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050052721.1	14	Reactome: R-HSA-71240;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-6936;Reactome: R-HSA-8964539;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;Reactome: R-HSA-8964208	"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Glutamate and glutamine metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Phenylalanine metabolism"
XP_050026344.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050051947.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050035939.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050042261.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8963901	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"VLDL assembly";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class F Receptors";"Scavenging by Class H Receptors";"Chylomicron assembly";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Chylomicron remodeling"
XP_050032331.1	17	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050047991.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050035196.1	12	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis I"
XP_050037146.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051	"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I"
XP_050039263.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050040208.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050030451.1	4	Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-6799198	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis"
XP_050047406.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050048265.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050046728.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050035985.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025	"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation"
XP_050049227.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050042177.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_050023397.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050044958.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050050137.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050047070.1	8	KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1	"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism"
XP_050044792.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050050573.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050050222.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050035732.1	3	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695	"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Neutrophil degranulation"
XP_050032120.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050022814.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050041886.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050044595.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_050035556.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_050040449.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_050024202.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050052269.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050022634.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_050045120.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050046059.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050042489.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050037279.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050033374.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex"
XP_050044088.1	5	Reactome: R-HSA-8964616;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-446388	"G beta:gamma signalling through CDC42";"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"
XP_050022815.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050044945.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050027821.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_050027179.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050024791.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050035403.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050027182.1	4	KEGG: 00633+2.3.1.5;Reactome: R-HSA-156582;KEGG: 00232+2.3.1.5;KEGG: 00983+2.3.1.5	"Nitrotoluene degradation";"Acetylation";"Caffeine metabolism";"Drug metabolism - other enzymes"
XP_050038200.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050032733.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_050052576.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050034240.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_050037722.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050043329.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050030827.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050046806.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050050246.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050040290.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050050264.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050050206.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050050907.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050041758.1	10	MetaCyc: PWY-4321;Reactome: R-HSA-916853;KEGG: 00410+2.6.1.19;KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;KEGG: 00640+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6535;MetaCyc: PWY-6537;MetaCyc: PWY-6536	"L-glutamate degradation IV";"Degradation of GABA";"beta-Alanine metabolism";"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"Propanoate metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation I";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III"
XP_050036830.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050034479.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050045577.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050041219.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050051359.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050044805.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050022643.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050029817.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050035018.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050051109.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-429947	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Deadenylation of mRNA"
XP_050049691.1	5	Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-8856825;Reactome: R-HSA-917937;Reactome: R-HSA-8951664	"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport";"Neddylation"
XP_050043742.1	10	MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-4041	"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle"
XP_050045031.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_050031278.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_050048972.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050039703.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050029322.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_050043301.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050049837.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;MetaCyc: PWY-7511;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050044624.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050025623.1	24	Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-392451	"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma"
XP_050049331.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050034721.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050039139.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050032691.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050025563.1	29	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape"
XP_050041932.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050027321.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050049812.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_050044911.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050024362.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050050551.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425	"Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_050038347.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050047729.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050032272.1	10	Reactome: R-HSA-9648895;Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72731	"Response of EIF2AK1 (HRI) to heme deficiency";"ABC-family proteins mediated transport";"PERK regulates gene expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Recycling of eIF2:GDP"
XP_050026830.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_050036626.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050034000.1	7	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-166208	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"mTORC1-mediated signalling"
XP_050024723.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050043295.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050050414.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761	"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_050027555.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050024825.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050027064.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050040580.1	8	MetaCyc: PWY-7717;MetaCyc: PWY-7733;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-5651;MetaCyc: PWY-6309	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxyquinaldate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_050045466.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050026814.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050026494.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050029317.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050039253.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050025435.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050043471.1	5	Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_050052272.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050045059.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050052697.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
XP_050038618.1	9	KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;MetaCyc: PWY-381	"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)"
XP_050044007.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050030822.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050029081.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_050033612.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050027588.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050029904.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050026263.1	5	Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-209543	"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes"
XP_050029736.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050039376.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050035042.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050052570.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050044405.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_050024311.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_050035533.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050045186.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050025979.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050045149.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_050038640.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050024123.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050029511.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050049881.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050051916.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723	"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation"
XP_050034125.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_050034437.1	5	KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050027966.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050051572.1	13	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-8948216	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Extracellular matrix organization";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"ECM proteoglycans";"Integrin cell surface interactions";"Laminin interactions";"Signaling by PDGF";"Collagen chain trimerization"
XP_050039388.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050045165.1	11	Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050023523.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050047185.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_050043320.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050043466.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_050044303.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050025899.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050023562.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050047249.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050052605.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050035431.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_050051946.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050049182.1	9	KEGG: 00960+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00350+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00360+2.6.1.5	"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine metabolism"
XP_050028332.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050049858.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_050040905.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050043062.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050026369.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050050841.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050044779.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050036457.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050028062.1	17	Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-1169091;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-4086398;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-202424;Reactome: R-HSA-5689880	"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"Ca2+ pathway";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling";"Ub-specific processing proteases"
XP_050040151.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050039208.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050030787.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050036223.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050029910.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050033707.1	7	Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4	"Synthesis of Ketone Bodies";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Peroxisomal protein import";"Butanoate metabolism";"Mevalonate degradation";"Synthesis and degradation of ketone bodies"
XP_050044317.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_050032146.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050039088.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis"
XP_050027576.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway"
XP_050036741.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050027550.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050027280.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050027639.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_050027731.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_050034383.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050037100.1	13	Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"LDL clearance";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_050040161.1	6	KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation"
XP_050051513.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050041339.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050052312.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050040455.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050037000.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050039295.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050030255.1	5	Reactome: R-HSA-9627069;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"Formation of apoptosome"
XP_050029924.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050025650.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-4041	"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle"
XP_050038995.1	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
XP_050024830.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050045838.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050032251.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050036659.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis"
XP_050039799.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050041191.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_050022980.1	28	Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-5696395;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of Incision Complex in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_050034132.1	6	KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;MetaCyc: PWY-6908;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-7356	"Thiamine metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)"
XP_050045591.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_050037400.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Neutrophil degranulation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050044419.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050040303.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050050794.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_050025361.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_050044237.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
YP_010283876.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050023474.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464	"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins"
XP_050049519.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_050041421.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045237.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050049757.1	26	Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-389960;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2500257	"MHC class II antigen presentation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Kinesins";"Resolution of Sister Chromatid Cohesion"
XP_050050156.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050050864.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_050022748.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050051581.1	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism"
XP_050044851.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050038680.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050041731.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050045348.1	5	KEGG: 00270+1.1.1.95;MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00260+1.1.1.95;KEGG: 00680+1.1.1.95	"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_050044445.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Peptide chain elongation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050026045.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050041491.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050044583.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050052225.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884	"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX"
XP_050050700.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-399719	"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors"
XP_050035779.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050023095.1	2	Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_050029756.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050039647.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-881907	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK"
XP_050023922.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_050040576.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-4261	"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerol degradation I"
XP_050051588.1	5	Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation"
XP_050047795.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050051511.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050026566.1	18	KEGG: 00010+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00310+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00640+1.8.1.4;Reactome: R-HSA-389661;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-70895;Reactome: R-HSA-6783984;Reactome: R-HSA-70268;MetaCyc: PWY-5084;KEGG: 00260+1.8.1.4;Reactome: R-HSA-5362517	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine degradation";"Lysine catabolism";"Lysine degradation";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Glycine degradation";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine, serine and threonine metabolism";"Signaling by Retinoic Acid"
XP_050050842.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050047789.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050045339.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050039039.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050031023.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_050025636.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050023611.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050032655.1	10	Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004	"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"EGFR downregulation";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity"
XP_050036429.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050042949.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050040649.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050024847.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050041003.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050026117.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050045874.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050049813.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_050048613.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_050025244.1	42	Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-5693565;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-977225;Reactome: R-HSA-5693571;Reactome: R-HSA-9616222;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-3214815;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-427389;Reactome: R-HSA-5625886;Reactome: R-HSA-73728;Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-5334118;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-427413	"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"PKMTs methylate histone lysines";"Amyloid fiber formation";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation of granulopoiesis";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Early Events";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"HDACs deacetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Meiotic recombination";"DNA methylation";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression"
XP_050034031.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome"
XP_050037530.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050045473.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050034659.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050042730.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_050024652.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_050049920.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050034983.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050051190.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_050028104.1	3	KEGG: 00983+2.1.1.67;Reactome: R-HSA-5578995;Reactome: R-HSA-156581	"Drug metabolism - other enzymes";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Methylation"
XP_050049413.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050040279.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050026799.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050037471.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050034257.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_050044028.1	2	Reactome: R-HSA-5682294;Reactome: R-HSA-1369062	"Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B";"ABC transporters in lipid homeostasis"
XP_050032483.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050033455.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050042417.1	5	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050039231.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050030942.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-165054	"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA"
XP_050039303.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050044544.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_050025576.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856	"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination"
XP_050042077.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
XP_050044406.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_050047965.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_050040191.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050034717.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050049715.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050034770.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050047807.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050040985.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050037409.1	12	KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Glycogen synthesis";"Galactose metabolism"
XP_050031593.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050038952.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050034747.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_050030035.1	5	Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168	"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_050024841.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736	"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors"
XP_050052359.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050027668.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_050034554.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_050047383.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050034676.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050042604.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050038321.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050037791.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050035192.1	12	MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053	"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II"
XP_050030100.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_050050079.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050042153.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050029390.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_050029177.1	5	Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661	"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050047027.1	10	MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15	"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism"
XP_050029882.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050027575.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050050175.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050051082.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050048930.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050022710.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_050022865.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_050037701.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050023676.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050044043.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_050051222.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050031815.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5469	"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis"
XP_050045407.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050046052.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050044647.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050042277.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050034672.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_050025493.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050032720.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8939902	"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Regulation of RUNX2 expression and activity"
XP_050030728.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050027724.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050047679.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050038988.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050035524.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050027775.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050050095.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050040984.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050023752.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_050042266.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050026370.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050033009.1	31	MetaCyc: PWY-4381;MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWY-7723;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-6282;MetaCyc: PWY-7858;MetaCyc: PWY-7746;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113;MetaCyc: PWY-7664;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-8012	"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Bacterial bioluminescence";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis"
XP_050026537.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050047074.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050047371.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6804760;Reactome: R-HSA-6804756;Reactome: R-HSA-69541;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580	"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence"
XP_050029816.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050026174.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050045529.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050050374.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050031114.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050037436.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_050022816.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050049469.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050028563.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050023877.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050025779.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050033934.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin"
XP_050030263.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050049588.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050030825.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050031537.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_050049203.1	18	MetaCyc: PWY-7383;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Arginine biosynthesis";"Sulfolactate degradation III";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Tyrosine metabolism";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism"
XP_050047184.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_050045674.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050049878.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050051948.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050034844.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050041924.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050051234.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050035406.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050041643.1	40	MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-6946;MetaCyc: PWY-5138;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-1361;MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-5177;MetaCyc: PWY-6863;MetaCyc: PWY-6883;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-7654;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-5109;MetaCyc: PWY-7726;KEGG: 00640+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7401;MetaCyc: PWY-7779	"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"Aminobenzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Geraniol degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid salvage";"Lysine degradation";"Fatty acid elongation";"Toluene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"2-methylpropene degradation";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glutaryl-coa degradation";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Caprolactam degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Phenylalanine metabolism";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol I";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl tert-butyl ether degradation"
XP_050036346.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050049346.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050048331.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050037728.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050039016.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis"
XP_050036254.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050043556.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050027290.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_050030676.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050032466.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_050041595.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050048720.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-532668;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601	"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_050042731.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_050040226.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_050040213.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_050031589.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050040731.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050038908.1	6	MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism"
XP_050049871.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050043316.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050050027.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism"
XP_050046556.1	17	KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6620;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;Reactome: R-HSA-74259;MetaCyc: PWY-6609	"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Purine catabolism";"Adenine and adenosine salvage III"
XP_050050015.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050041926.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050052710.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_050032522.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050042252.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_050028047.1	2	Reactome: R-HSA-174577;Reactome: R-HSA-977606	"Activation of C3 and C5";"Regulation of Complement cascade"
XP_050036446.1	5	MetaCyc: PWY-5046;Reactome: R-HSA-389661;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4	"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism"
XP_050044359.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050045511.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050051338.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050049758.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport"
XP_050039770.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050023286.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050036918.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050033226.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_050024357.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_050036233.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050033008.1	31	MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-7746;MetaCyc: PWY-7858;MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8047;MetaCyc: PWY-5971;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWYG-321;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-4381	"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_050026017.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362300	"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050036709.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050032118.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050048565.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050033132.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050030804.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050048003.1	1	Reactome: R-HSA-1989781	"PPARA activates gene expression"
XP_050043088.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050038963.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Nonhomologous End-Joining (NHEJ)"
XP_050051708.1	3	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_050044781.1	11	Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986	"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2"
XP_050028061.1	17	Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-1169091;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-168638	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of NF-kappaB in B cells";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"Ca2+ pathway";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway"
XP_050022836.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050036034.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050050924.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050035167.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_050035428.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050051540.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_050041538.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050028858.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050050558.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050051668.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_050045828.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_050040907.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050034062.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050037524.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050023969.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050031345.1	6	Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_050034382.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050042439.1	6	MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism"
XP_050042025.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-9604323	"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling"
XP_050049181.1	9	KEGG: 00401+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00400+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00270+2.6.1.5	"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine catabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism"
XP_050047770.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_050025780.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050045659.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_050041309.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_050044586.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050024689.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050029884.1	1	Reactome: R-HSA-166208	"mTORC1-mediated signalling"
XP_050026955.1	11	Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972	"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050025458.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050043349.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050048210.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050041386.1	2	Reactome: R-HSA-606279;Reactome: R-HSA-6783310	"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway"
XP_050042036.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050040903.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050024098.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050023019.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050031403.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050034127.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_050031169.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_050027178.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050050100.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050027309.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_050042299.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050036823.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050040212.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_050023304.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050036552.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050049231.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050034736.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050038831.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_050045477.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_050023734.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_050048815.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_050022667.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050048785.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050024420.1	4	KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_050027284.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050048810.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_050028031.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050044056.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_050024087.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050049827.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_050024508.1	16	Reactome: R-HSA-975155;Reactome: R-HSA-5603037;Reactome: R-HSA-5602680;Reactome: R-HSA-1236974;Reactome: R-HSA-1810476;Reactome: R-HSA-975871;Reactome: R-HSA-5602498;Reactome: R-HSA-1257604;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-209543;Reactome: R-HSA-6811558;Reactome: R-HSA-3134963;Reactome: R-HSA-9020702;Reactome: R-HSA-166058;Reactome: R-HSA-975138	"MyD88 dependent cascade initiated on endosome";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR5)";"ER-Phagosome pathway";"RIP-mediated NFkB activation via ZBP1";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"p75NTR recruits signalling complexes";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"Interleukin-1 signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_050049665.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050045411.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050043787.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050044796.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_050049365.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_050045786.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050044033.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050022581.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_050022594.1	17	Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-174414	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere"
XP_050050944.1	5	Reactome: R-HSA-4755579;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-446199	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_050045341.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050042691.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_050036231.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050036578.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050050871.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050046313.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_050028081.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050027975.1	13	MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2022857	"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Keratan sulfate degradation"
XP_050034235.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_050051416.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050036006.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_050047704.1	9	MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18	"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione metabolism"
XP_050041851.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050035552.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050037311.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_050045187.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050027598.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_050042308.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050042348.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050050331.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050023751.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_050035477.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050052302.1	33	MetaCyc: PWY-6342;KEGG: 00680+1.1.1.284;MetaCyc: PWY-7013;MetaCyc: PWY-5076;MetaCyc: PWY-6587;KEGG: 00626+1.1.1.1;KEGG: 00625+1.1.1.1;KEGG: 00830+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-6802;MetaCyc: PWY-5082;MetaCyc: PWY-6333;MetaCyc: PWY-5480;MetaCyc: PWY-5486;KEGG: 00980+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00071+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-3162;Reactome: R-HSA-71384;MetaCyc: PWY-5079;MetaCyc: PWY-7396;MetaCyc: PWY-7798;MetaCyc: PWY-6871;MetaCyc: PWY-1801;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-5057;MetaCyc: PWY-7118;MetaCyc: PWY-5078;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5751	"Noradrenaline and adrenaline degradation";"Methane metabolism";"(S)-propane-1,2-diol degradation";"L-leucine degradation III";"Pyruvate fermentation to ethanol III";"Naphthalene degradation";"Chloroalkane and chloroalkene degradation";"Retinol metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to isobutanol (engineered)";"Salidroside biosynthesis";"L-methionine degradation III";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to ethanol II";"Metabolism of xenobiotics by cytochrome P450";"Glycine, serine and threonine metabolism";"Fatty acid degradation";"Drug metabolism - cytochrome P450";"L-tryptophan degradation V (side chain pathway)";"Ethanol oxidation";"L-phenylalanine degradation III";"Butanol and isobutanol biosynthesis (engineered)";"Protein S-nitrosylation and denitrosylation";"3-methylbutanol biosynthesis (engineered)";"Formaldehyde oxidation II (glutathione-dependent)";"alpha-Linolenic acid metabolism";"Serotonin degradation";"L-valine degradation II";"Chitin degradation to ethanol";"L-isoleucine degradation II";"Tyrosine metabolism";"Phenylethanol biosynthesis"
XP_050041016.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050027247.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050050512.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050049923.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050036998.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050045410.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027218.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050029504.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050048621.1	30	KEGG: 05163+2.7.11.1;Reactome: R-HSA-198693;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-389513;Reactome: R-HSA-199418;Reactome: R-HSA-8948751;Reactome: R-HSA-389357;Reactome: R-HSA-9634638;Reactome: R-HSA-1358803;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804759;Reactome: R-HSA-211163;Reactome: R-HSA-198323;Reactome: R-HSA-9614399;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-8876198;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-69202;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69656;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"AKT phosphorylates targets in the nucleus";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"RUNX2 regulates genes involved in cell migration";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Regulation of TP53 Activity through Acetylation";"CTLA4 inhibitory signaling";"Negative regulation of the PI3K/AKT network";"Regulation of PTEN stability and activity";"CD28 dependent PI3K/Akt signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of ERBB2:ERBB3 signaling";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Association with Co-factors";"AKT-mediated inactivation of FOXO1A";"AKT phosphorylates targets in the cytosol";"Regulation of localization of FOXO transcription factors";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"RAB GEFs exchange GTP for GDP on RABs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Relaxin signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"mTOR signaling pathway"
XP_050052630.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050032010.1	60	KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;MetaCyc: PWY-7606;KEGG: 00280+4.2.1.17;KEGG: 00380+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-5138;MetaCyc: PWY-7656;Reactome: R-HSA-77350;KEGG: 00627+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00930+4.2.1.17;Reactome: R-HSA-77305;KEGG: 00623+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7094;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;Reactome: R-HSA-1482798;MetaCyc: PWY-6863;MetaCyc: PWY-5177;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;Reactome: R-HSA-77348;KEGG: 00592+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00410+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-7007;MetaCyc: PWY-7401;MetaCyc: PWY-7779;MetaCyc: PWY-6583;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00650+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-7726;KEGG: 00281+4.2.1.17;Reactome: R-HSA-77346;Reactome: R-HSA-77285;MetaCyc: PWY-7216;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-6944	"Carbon fixation pathways in prokaryotes";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Spodoptera littoralis pheromone biosynthesis";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Aminobenzoate degradation";"Benzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Caprolactam degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Toluene degradation";"Fatty acid degradation";"Fatty acid degradation";"Lysine degradation";"Fatty acid elongation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid salvage";"Limonene and pinene degradation";"Geraniol degradation";"Lysine degradation";"Butanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"Acyl chain remodeling of CL";"Pyruvate fermentation to hexanol (engineered)";"Glutaryl-coa degradation";"Fatty acid elongation";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"2-methylpropene degradation";"beta-Alanine metabolism";"Benzoyl-coa degradation I (aerobic)";"Methyl ketone biosynthesis (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol I";"Valine, leucine and isoleucine degradation";"Carbon fixation pathways in prokaryotes";"Phenylalanine metabolism";"Propanoate metabolism";"Butanoate metabolism";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Geraniol degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Caprolactam degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation"
XP_050049729.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050051688.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050023262.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050025227.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050027083.1	7	Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050035429.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_050024177.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-445355	"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_050027510.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050044470.1	56	Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-68949	"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin"
XP_050047428.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050026485.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_050036693.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050043319.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050037023.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_050039684.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050038789.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-165181	"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB"
XP_050029889.1	8	Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638	"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"HCMV Early Events";"SUMOylation of chromatin organization proteins"
XP_050023422.1	19	Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888	"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"VLDL assembly";"Chylomicron remodeling";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"VLDL clearance";"Scavenging by Class H Receptors";"Chylomicron assembly"
XP_050032605.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050024480.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050034961.1	17	Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-75035;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-5693616	"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by SCF-KIT";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"Thermogenesis";"Transcriptional Regulation by E2F6";"Human cytomegalovirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050030855.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050032316.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050032599.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition"
XP_050024186.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050044625.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050033466.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050049643.1	5	Reactome: R-HSA-9608287;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-9608290;Reactome: R-HSA-110331	"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Defective MUTYH substrate processing";"Cleavage of the damaged purine"
XP_050025720.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050039753.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922	"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_050048973.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050051387.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050042739.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050040159.1	6	Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66	"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_050046032.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050034322.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050035432.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050045029.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050028615.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_050024178.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-445355	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"MAP2K and MAPK activation";"Platelet degranulation";"Smooth Muscle Contraction"
XP_050023275.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050041754.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_050025946.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050051251.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050022773.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050049122.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050037479.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050025083.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050029316.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050041694.1	10	Reactome: R-HSA-1989781;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-922	"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Mevalonate pathway II (archaea)";"Mevalonate pathway I"
XP_050026777.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050026810.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159236	"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050041503.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
XP_050038362.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050050690.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-877300	"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF activation";"Interferon gamma signaling"
XP_050050272.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050037310.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination"
XP_050042354.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050049805.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050041799.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050049052.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_050024500.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050026498.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050047757.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050050796.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_050026812.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050023284.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050046934.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050025982.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050024315.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050029900.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050048629.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050032576.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER"
XP_050051917.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569	"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_050039296.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027559.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050040509.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050028562.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050046709.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050045749.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_050049014.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_050035209.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050047049.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050032227.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050044924.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050044449.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050030794.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050026536.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050044293.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050035084.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050050904.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050032654.1	10	Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-432720	"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis"
XP_050033785.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050027316.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050039126.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041	"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis"
XP_050048221.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050031536.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050045469.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050051928.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050043945.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_050026958.1	7	Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841	"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"HCMV Early Events";"PKMTs methylate histone lysines"
XP_050027121.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050048625.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050037412.1	12	KEGG: 00052+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9	"Galactose metabolism";"Glycogen synthesis";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism"
XP_050031112.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050026122.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050033786.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050049452.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050039027.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation"
XP_050035497.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050034610.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050039294.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050041243.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050029381.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050026760.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050046277.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050038972.1	10	MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-6886	"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)"
XP_050033403.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050042500.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050049773.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050029769.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050038430.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050041005.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050022944.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin"
XP_050027255.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_050027028.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_050052582.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050040729.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676	"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle"
XP_050043550.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050032675.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050041310.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050047164.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050050959.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050028705.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050026975.1	8	Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_050041662.1	9	MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003	"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol"
XP_050052267.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050032608.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050026917.1	13	KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883	"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II"
XP_050042167.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_050050658.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620912	"Hedgehog 'off' state";"Anchoring of the basal body to the plasma membrane"
XP_050049142.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050045897.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)"
XP_050033662.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050038646.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_050035762.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050039432.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050041725.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050039028.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050030697.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050048008.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050026341.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050045233.1	8	MetaCyc: PWY-5;Reactome: R-HSA-70635;MetaCyc: PWY-5154;KEGG: 00250+4.3.2.1;KEGG: 00220+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-4984;MetaCyc: PWY-4983	"Canavanine biosynthesis";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Nitric oxide biosynthesis II (mammals)"
XP_050028706.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050048146.1	7	KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Streptomycin biosynthesis"
XP_050042243.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050026422.1	42	KEGG: 00592+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-7007;MetaCyc: PWY-1361;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6863;MetaCyc: PWY-5177;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-5109;MetaCyc: PWY-7726;MetaCyc: PWY-7216;MetaCyc: PWY-7654;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-7779;MetaCyc: PWY-7401;MetaCyc: PWY-6583;KEGG: 00360+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7656;MetaCyc: PWY-5138;MetaCyc: PWY-6946;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6945;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35	"alpha-Linolenic acid metabolism";"Fatty acid degradation";"beta-Alanine metabolism";"2-methylpropene degradation";"Methyl ketone biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Glutaryl-coa degradation";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Caprolactam degradation";"Androstenedione degradation";"Methyl tert-butyl ether degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Phenylalanine metabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Aminobenzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid elongation";"Lysine degradation";"Fatty acid salvage";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Limonene and pinene degradation";"Geraniol degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"Fatty acid degradation"
XP_050039357.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050027688.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050039344.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050034254.1	15	MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-8004	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I"
XP_050033249.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050049988.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050034801.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050031079.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050051524.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050041618.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050045823.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_050036730.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050025183.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050028977.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050050764.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050050797.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050033516.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050051713.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050050236.1	6	MetaCyc: PWY-6364;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050026424.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050039855.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050044778.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050024205.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050027554.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050028335.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050045961.1	6	MetaCyc: PWY-6599;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.8;MetaCyc: PWY-6610;MetaCyc: PWY-6620;KEGG: 00983+2.4.2.8	"Guanine and guanosine salvage II";"Adenine and adenosine salvage III";"Purine metabolism";"Adenine salvage";"Guanine and guanosine salvage";"Drug metabolism - other enzymes"
XP_050052242.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357	"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling"
XP_050049023.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050038700.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_050041916.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050039072.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_050035249.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050050698.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692	"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity"
XP_050044604.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050042307.1	12	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"mTOR signaling pathway";"Macroautophagy";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes"
XP_050030167.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_050029072.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826	"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis"
XP_050027302.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050039818.1	5	Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants"
XP_050023495.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050038966.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168276	"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways"
XP_050042819.1	3	Reactome: R-HSA-193368;Reactome: R-HSA-159418;Reactome: R-HSA-5678520	"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Recycling of bile acids and salts";"Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2"
XP_050039758.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050043802.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_050025176.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050051756.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050041743.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050033565.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050042127.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050048821.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565	"Th1 and Th2 cell differentiation";"ESR-mediated signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050034951.1	8	KEGG: 04660+3.1.3.16;MetaCyc: PWY-5269;MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 00564+3.1.3.27;KEGG: 04658+3.1.3.16;Reactome: R-HSA-1483148;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Th1 and Th2 cell differentiation";"Synthesis of PG";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050037525.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050035872.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050030832.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050033747.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050037844.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050032943.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050038964.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_050042256.1	7	MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-5316;Reactome: R-HSA-196807;KEGG: 00760+6.3.4.21;MetaCyc: PWY-7342;KEGG: 00760+2.4.2.19	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotine biosynthesis";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Superpathway of nicotine biosynthesis";"Nicotinate and nicotinamide metabolism"
XP_050033755.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050032071.1	10	Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_050050080.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050048503.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_050024395.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_050023779.1	18	Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167287	"mRNA Capping";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery"
XP_050043121.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050037104.1	5	Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111469	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC, XIAP-regulated apoptotic response"
XP_050024499.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050049600.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050052168.1	4	MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism"
XP_050041589.1	4	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_050036769.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050044082.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050037088.1	12	Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_050030823.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050034502.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050038111.1	2	Reactome: R-HSA-74259;KEGG: 00230+3.6.1.66	"Purine catabolism";"Purine metabolism"
XP_050025512.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027445.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050042052.1	7	MetaCyc: PWY-6724;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-7238	"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation V";"Sucrose biosynthesis II"
XP_050052047.1	9	Reactome: R-HSA-5649702;Reactome: R-HSA-9657050;Reactome: R-HSA-110357;Reactome: R-HSA-9656255;Reactome: R-HSA-9656256;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110328	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Localization";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Binding";"Defective OGG1 Substrate Processing";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_050044830.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_050031039.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050044775.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050049890.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050046979.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20	"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050042802.1	5	Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-5334118	"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"DNA methylation"
XP_050023575.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050049164.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050051492.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050038125.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050049422.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050039327.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050035149.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050040340.1	15	Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-141430	"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_050035955.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050036354.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050046497.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_050049541.1	11	MetaCyc: PWY-6607;MetaCyc: PWY-7821;MetaCyc: PWY-5695;MetaCyc: PWY-6606;KEGG: 00230+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-7185;MetaCyc: PWY-6596;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5381	"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"UTP and CTP dephosphorylation I";"Adenosine nucleotides degradation I";"Pyrimidine metabolism";"Pyridine nucleotide cycling (plants)"
XP_050045396.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050043318.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050040824.1	17	Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_050029897.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_050043725.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050024131.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050038469.1	40	Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-5617472	"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050025066.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050047837.1	8	MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5740;Reactome: R-HSA-6787639;MetaCyc: PWY-5739;MetaCyc: PWY-66;KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573	"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-colitose biosynthesis";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis"
XP_050035791.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050051138.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050038826.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_050027720.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050031590.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050027158.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050028604.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050040995.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050036878.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050050072.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050023267.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050038786.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050051674.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050030445.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050049590.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_050039278.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050036485.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050052518.1	4	Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_050035835.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050039888.1	3	Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709	"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins"
XP_050039437.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050049170.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050036003.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050029683.1	7	Reactome: R-HSA-140837;Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-114608	"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (i) signalling events";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation"
XP_050027024.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
XP_050037576.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Betanidin degradation"
XP_050045441.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050029555.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050044238.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_050024453.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050029780.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050045193.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050026115.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050045247.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_050023711.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050038207.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050032731.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050024913.1	4	Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050026502.1	5	MetaCyc: PWY-7185;MetaCyc: PWY-7176;MetaCyc: PWY-7177;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2	"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_050025348.1	20	Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604	"mTORC1-mediated signalling";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"Thermogenesis";"HSF1-dependent transactivation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signalling";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Relaxin signaling pathway";"PIP3 activates AKT signaling"
XP_050050069.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050043208.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_050040428.1	29	Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-5696400	"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER"
XP_050040640.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050039212.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_050047036.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050046843.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050047182.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050045464.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050035168.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_050033446.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050048717.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-2173796;Reactome: R-HSA-176034	"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interactions of Tat with host cellular proteins"
XP_050049594.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050039772.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041	"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis"
XP_050041668.1	9	MetaCyc: PWY-8004;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042	"Entner-Doudoroff pathway I";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)"
XP_050049157.1	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation"
XP_050024198.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050037441.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050038144.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins"
XP_050029418.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050039847.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050024720.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050039424.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050023014.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050049499.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476	"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1"
XP_050036431.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050043344.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050030801.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050027577.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway"
XP_050038595.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050032510.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_050048893.1	12	Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-977225	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation"
XP_050049030.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050030935.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050040739.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050027941.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050038855.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_050035314.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050024521.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050045544.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050045188.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050045431.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050025608.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050039710.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050029972.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050025418.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050036543.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050030686.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050024179.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695	"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Neutrophil degranulation"
XP_050052020.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050023887.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050038965.1	7	Reactome: R-HSA-5693565;Reactome: R-HSA-983168;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050038462.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_050047066.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050050696.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892	"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation"
XP_050035478.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050025637.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050039393.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050046734.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport"
XP_050044529.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483	"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Macroautophagy";"Activation of AMPK downstream of NMDARs"
XP_050023621.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050039704.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_050028692.1	6	Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050025036.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050026853.1	3	Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426	"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050026011.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050034623.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050028469.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis"
XP_050028763.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050045376.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050040198.1	58	Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5689901;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780	"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Metalloprotease DUBs";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome"
XP_050039549.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_050030625.1	3	Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050029793.1	2	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_050047570.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_050038738.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050045362.1	7	KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;Reactome: R-HSA-9022692;Reactome: R-HSA-191273;MetaCyc: PWY-6074;MetaCyc: PWY-7154;MetaCyc: PWY-2541	"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Regulation of MECP2 expression and activity";"Cholesterol biosynthesis";"Zymosterol biosynthesis";"Ergosterol biosynthesis II";"Phytosterol biosynthesis (plants)"
XP_050023889.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050034093.1	4	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050047213.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050044170.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050027344.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050047992.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_050050903.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050032515.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Ub-specific processing proteases"
XP_050046963.1	3	Reactome: R-HSA-73772;Reactome: R-HSA-427389;Reactome: R-HSA-8953750	"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Transcriptional Regulation by E2F6"
XP_050033576.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050033835.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050031263.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5466	"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis"
XP_050051774.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050049146.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050045184.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050025547.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_050048825.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050025606.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050025915.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050049663.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050025302.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050037062.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_050046640.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_050028341.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050043380.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050031171.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050037264.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050034735.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_050034819.1	5	Reactome: R-HSA-196843;MetaCyc: PWY-7863;MetaCyc: PWY-5523;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26	"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism"
XP_050034809.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-166208	"HSF1-dependent transactivation";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling"
XP_050042262.1	19	Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-381426	"Chylomicron remodeling";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Chylomicron assembly";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"VLDL clearance";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"VLDL assembly";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050037282.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050024731.1	7	Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-201681	"PCP/CE pathway";"WNT mediated activation of DVL";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT"
XP_050030803.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050044467.1	7	Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_050034930.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050024076.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050031141.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_050023297.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050045032.1	22	MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-6433;MetaCyc: PWY-7606;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7592;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7035;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7728;MetaCyc: PWY-7726	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_050036212.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050029320.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_050049307.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050026954.1	11	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"mTOR signaling pathway"
XP_050046878.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050027354.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050031784.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_050026606.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050028874.1	9	KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549	"Arginine biosynthesis";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III"
XP_050028561.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050040209.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183	"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_050051735.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_050023363.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050042294.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050038798.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_050025206.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050041981.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050044402.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_050031834.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation"
XP_050022968.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050026959.1	7	Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"HCMV Early Events";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription"
XP_050036371.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050038967.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168325	"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis"
XP_050036756.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050050114.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050051992.1	8	MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation"
XP_050049824.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050047963.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050039079.1	3	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_050032128.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050036269.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050025561.1	12	MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263	"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Gluconeogenesis"
XP_050037856.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7589	"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_050038145.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050044041.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_050048187.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050025707.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050048200.1	15	Reactome: R-HSA-9665244;Reactome: R-HSA-9652282;Reactome: R-HSA-9664565;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9665246;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-1236382;Reactome: R-HSA-9665233;Reactome: R-HSA-9634285;Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986	"Resistance of ERBB2 KD mutants to sapitinib";"Drug-mediated inhibition of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to neratinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2"
XP_050039794.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050028080.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050038433.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050049363.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050049523.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_050036131.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050038622.1	9	MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2	"Ammonia assimilation cycle II";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism"
XP_050047259.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050040196.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_050036558.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_050040210.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183	"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_050045051.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_050051716.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_050028292.1	29	KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-6803207;Reactome: R-HSA-6804760;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-6803204;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-349425;Reactome: R-HSA-5693616	"Relaxin signaling pathway";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"Stabilization of p53";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Methylation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Thermogenesis";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Human cytomegalovirus infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Autodegradation of the E3 ubiquitin ligase COP1";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050047315.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050039394.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050024034.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050032009.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050046027.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_050030795.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050044436.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050051750.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050029338.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_050027469.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis"
XP_050039712.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050045758.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050029899.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050026487.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050032942.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050038858.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050022757.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050040257.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050035075.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050045274.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_050044212.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050048363.1	1	Reactome: R-HSA-8856825	"Cargo recognition for clathrin-mediated endocytosis"
XP_050027253.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050025123.1	2	Reactome: R-HSA-139853;Reactome: R-HSA-418346	"Elevation of cytosolic Ca2+ levels";"Platelet homeostasis"
XP_050041146.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050042708.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050047598.1	44	Reactome: R-HSA-5673001;Reactome: R-HSA-444257;Reactome: R-HSA-2559585;Reactome: R-HSA-5674135;Reactome: R-HSA-982772;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-170968;Reactome: R-HSA-881907;Reactome: R-HSA-6802946;Reactome: R-HSA-5654732;Reactome: R-HSA-198753;Reactome: R-HSA-6802952;Reactome: R-HSA-5654727;Reactome: R-HSA-8943724;Reactome: R-HSA-1295596;Reactome: R-HSA-9634638;Reactome: R-HSA-5654733;Reactome: R-HSA-6802948;Reactome: R-HSA-162658;Reactome: R-HSA-8939211;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5663213;Reactome: R-HSA-3371453;Reactome: R-HSA-6802955;Reactome: R-HSA-112409;Reactome: R-HSA-2871796;Reactome: R-HSA-5668599;Reactome: R-HSA-450341;Reactome: R-HSA-456926;Reactome: R-HSA-5654726;Reactome: R-HSA-6811558;Reactome: R-HSA-2559582;Reactome: R-HSA-8940973;Reactome: R-HSA-74749;Reactome: R-HSA-879415;Reactome: R-HSA-2029482;Reactome: R-HSA-9635465;Reactome: R-HSA-202670;Reactome: R-HSA-445144;Reactome: R-HSA-9627069;Reactome: R-HSA-5674499;Reactome: R-HSA-2559580;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"RSK activation";"Oncogene Induced Senescence";"MAP2K and MAPK activation";"Growth hormone receptor signaling";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Frs2-mediated activation";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR3 signaling";"ERK/MAPK targets";"Signaling by BRAF and RAF fusions";"Negative regulation of FGFR2 signaling";"Regulation of PTEN gene transcription";"Spry regulation of FGF signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of FGFR4 signaling";"Signaling by high-kinase activity BRAF mutants";"Golgi Cisternae Pericentriolar Stack Reorganization";"ESR-mediated signaling";"mTOR signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of HSF1-mediated heat shock response";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF-independent MAPK1/3 activation";"FCERI mediated MAPK activation";"RHO GTPases Activate NADPH Oxidases";"Activation of the AP-1 family of transcription factors";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR1 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX2 regulates osteoblast differentiation";"Signal attenuation";"Advanced glycosylation endproduct receptor signaling";"Regulation of actin dynamics for phagocytic cup formation";"Suppression of apoptosis";"ERKs are inactivated";"Signal transduction by L1";"Regulation of the apoptosome activity";"Negative feedback regulation of MAPK pathway";"Oxidative Stress Induced Senescence";"NCAM signaling for neurite out-growth"
XP_050025080.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050025618.1	13	KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101	"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"CS/DS degradation"
XP_050027717.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050050755.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050029180.1	10	MetaCyc: PWY-7661;KEGG: 00510+2.4.1.83;Reactome: R-HSA-913709;MetaCyc: PWY-7922;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-162699;Reactome: R-HSA-4719360	"Protein N-glycosylation (Haloferax volcanii)";"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_050039965.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050029216.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050034679.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050036247.1	6	Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1489509	"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"DAG and IP3 signaling"
XP_050051601.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050027425.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050035973.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050031050.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050042953.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050047758.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050043036.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050024735.1	4	Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_050048865.1	12	KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.2;Reactome: R-HSA-196780;KEGG: 00230+6.3.3.1;KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6277;MetaCyc: PWY-6613;MetaCyc: PWY-6122	"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Biotin transport and metabolism";"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_050022583.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050050593.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050044850.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050035447.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_050036058.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050044844.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050050237.1	6	MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_050027464.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-5651801	"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair"
XP_050049406.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_050049347.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050047231.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_050044346.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050032571.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)"
XP_050039852.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050041399.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050052584.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050044253.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050047796.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050047670.1	30	Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2894862;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-5610780;Reactome: R-HSA-1170546;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-9604323;Reactome: R-HSA-2565942;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-917937;Reactome: R-HSA-2122947;Reactome: R-HSA-180534;Reactome: R-HSA-2644606;Reactome: R-HSA-983168	"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"Degradation of GLI1 by the proteasome";"Prolactin receptor signaling";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of NOTCH4 signaling";"Regulation of PLK1 Activity at G2/M Transition";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Iron uptake and transport";"NOTCH1 Intracellular Domain Regulates Transcription";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050033611.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050025715.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764	"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"ER-Phagosome pathway";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling"
XP_050032926.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050023769.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050042302.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050047642.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050051714.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050051246.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050051502.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050030922.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050042392.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168325	"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis"
XP_050032496.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050029240.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050043037.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050051289.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050024895.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027367.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050045785.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-8941858	"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity"
XP_050038767.1	6	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-983168;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Antigen processing: Ubiquitination & Proteasome degradation";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins"
XP_050026207.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_050041237.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050023445.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050026396.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050034903.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050034929.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050025557.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050038596.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050048963.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050041797.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050044105.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050042035.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050042300.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050034083.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050030591.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214	"Betanidin degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_050050913.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050030365.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050051506.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_050038117.1	5	MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32	"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_050031163.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050043900.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_050046171.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050023531.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050038746.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050044252.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050048718.1	15	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-9018519	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression"
XP_050041911.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050035991.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050040600.1	11	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD"
XP_050025028.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050032859.1	9	Reactome: R-HSA-5628897;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"MAP2K and MAPK activation";"Neutrophil degranulation";"mTOR signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050033021.1	11	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8866654;Reactome: R-HSA-3270619;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"IRF3-mediated induction of type I IFN";"mTOR signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)"
XP_050048206.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050029898.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050033913.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050023852.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_050036613.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050031158.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050029087.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_050036357.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050046879.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050044400.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_050038949.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050028035.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050036414.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050047788.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050024488.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050037151.1	12	MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_050023461.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_050052633.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045826.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_050032801.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050045596.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050030531.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050025900.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050037410.1	12	Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-3801;MetaCyc: PWY-6527;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9	"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Sucrose biosynthesis II";"Glycogen synthesis";"Galactose metabolism"
XP_050029439.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050034280.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050052609.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050025938.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-5870;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5857	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_050026778.1	4	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_050025973.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050043905.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050024721.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050051567.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_050030611.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050050863.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050045538.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050040090.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050027441.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050039198.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_050042225.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_050041842.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050040416.1	8	MetaCyc: PWY-7717;MetaCyc: PWY-7733;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7765;MetaCyc: PWY-5651;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxyquinaldate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis"
XP_050032842.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050031194.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050046465.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050023742.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050046592.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050034948.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_050044282.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050044195.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_050034827.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_050040584.1	8	MetaCyc: PWY-6309;MetaCyc: PWY-5651;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733;MetaCyc: PWY-7717	"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_050052033.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050039128.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050049806.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050052022.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050029361.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_050038286.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism"
XP_050048261.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_050042180.1	6	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism"
XP_050045750.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_050025266.1	42	Reactome: R-HSA-427389;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-3214815;Reactome: R-HSA-5250924;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5334118;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-3214841;Reactome: R-HSA-977225;Reactome: R-HSA-5693571;Reactome: R-HSA-9616222;Reactome: R-HSA-5693565;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-3214847;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-110331;Reactome: R-HSA-9018519	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"HDACs deacetylate histones";"B-WICH complex positively regulates rRNA expression";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"DNA methylation";"Meiotic recombination";"RMTs methylate histone arginines";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"PKMTs methylate histone lysines";"Amyloid fiber formation";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation of granulopoiesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Cleavage of the damaged purine";"Estrogen-dependent gene expression"
XP_050051979.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_050048028.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050024093.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_050050679.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948	"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants"
XP_050038751.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867	"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex"
XP_050032921.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_050025756.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_050035870.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050029773.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050046311.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050036852.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_050027442.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050051764.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598	"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis"
XP_050045632.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050023491.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050051033.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_050031998.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050035484.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_050048786.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_050045597.1	14	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-1632852;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-68877	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Macroautophagy";"Separation of Sister Chromatids";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Intraflagellar transport";"COPI-mediated anterograde transport";"Mitotic Prometaphase"
XP_050032707.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050046147.1	17	Reactome: R-HSA-1538133;Reactome: R-HSA-113501;Reactome: R-HSA-111448;Reactome: R-HSA-2173796;Reactome: R-HSA-8953750;Reactome: R-HSA-139915;Reactome: R-HSA-69205;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-69231	"G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of NOXA and translocation to mitochondria";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional Regulation by E2F6";"Activation of PUMA and translocation to mitochondria";"G1/S-Specific Transcription";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1"
XP_050028967.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050039561.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050030939.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5689880	"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Ub-specific processing proteases"
XP_050023108.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_050027715.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_050025064.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-159230	"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA"
XP_050045946.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050039318.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050022623.1	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
XP_050047354.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050031783.1	10	MetaCyc: PWY-6317;MetaCyc: PWY-6397;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-7344;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2	"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Galactose metabolism";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism"
XP_050042022.1	7	MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050040189.1	6	Reactome: R-HSA-173599;MetaCyc: PWY-7346;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22	"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism"
XP_050040089.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050034984.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050040348.1	5	KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_050030021.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050032998.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis"
XP_050036353.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050029492.1	18	MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7187;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7205	"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"CMP phosphorylation"
XP_050034249.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
XP_050045531.1	6	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_050033760.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050050943.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_050052034.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050039319.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050029435.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050031906.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_050025068.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050027435.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_050045027.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050026339.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050041602.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050029078.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
XP_050044483.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050042112.1	24	Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-9634600;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-111931;Reactome: R-HSA-180024;Reactome: R-HSA-9010642;Reactome: R-HSA-5610787;Reactome: R-HSA-422356;Reactome: R-HSA-4420097;Reactome: R-HSA-163615;Reactome: R-HSA-392517;Reactome: R-HSA-164378;Reactome: R-HSA-163560;Reactome: R-HSA-432040;Reactome: R-HSA-5610785;Reactome: R-HSA-5621575;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5687128;Reactome: R-HSA-8963896;Reactome: R-HSA-8853659;Reactome: R-HSA-442720;Reactome: R-HSA-983231	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"PKA-mediated phosphorylation of CREB";"DARPP-32 events";"ROBO receptors bind AKAP5";"Hedgehog 'off' state";"Regulation of insulin secretion";"VEGFA-VEGFR2 Pathway";"PKA activation";"Rap1 signalling";"PKA activation in glucagon signalling";"Triglyceride catabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"GLI3 is processed to GLI3R by the proteasome";"CD209 (DC-SIGN) signaling";"mTOR signaling pathway";"MAPK6/MAPK4 signaling";"HDL assembly";"RET signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production"
XP_050048788.1	1	KEGG: 00760+1.4.1.21	"Nicotinate and nicotinamide metabolism"
XP_050035770.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-191859	"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly"
XP_050040116.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050032548.1	24	Reactome: R-HSA-165158;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5625740;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-202424;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5674400;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 05165+2.7.11.1	"Activation of AKT2";"PI3K-Akt signaling pathway";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"RHO GTPases activate PKNs";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Downstream TCR signaling";"Human cytomegalovirus infection";"RSK activation";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"Constitutive Signaling by AKT1 E17K in Cancer";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"CLEC7A (Dectin-1) signaling";"Human papillomavirus infection"
XP_050050345.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050045244.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050037106.1	3	Reactome: R-HSA-5083635;Reactome: R-HSA-189085;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins"
XP_050042271.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050023362.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050042367.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_050024067.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050038583.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050032647.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)"
XP_050030590.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Betanidin degradation"
XP_050025991.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_050030202.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050033958.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050048978.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050036708.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050040110.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050035467.1	4	MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22	"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism"
XP_050041995.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962	"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex"
XP_050031909.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_050045451.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00010+5.3.1.1;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+5.3.1.1	"Glycolysis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms"
XP_050024722.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-4086400;Reactome: R-HSA-201688	"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"PCP/CE pathway";"WNT mediated activation of DVL"
XP_050050090.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050032802.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050046062.1	20	Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5696400	"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER"
XP_050045111.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050044667.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_050039466.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_050049856.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050035481.1	179	Reactome: R-HSA-8856825;Reactome: R-HSA-3769402;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-9013973;Reactome: R-HSA-8866652;Reactome: R-HSA-5658442;Reactome: R-HSA-5675482;Reactome: R-HSA-5689901;Reactome: R-HSA-937039;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-6782210;Reactome: R-HSA-2672351;Reactome: R-HSA-168927;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-9637628;Reactome: R-HSA-5358346;Reactome: R-HSA-175474;Reactome: R-HSA-5205685;Reactome: R-HSA-72764;Reactome: R-HSA-532668;Reactome: R-HSA-5654726;Reactome: R-HSA-168928;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-8948747;Reactome: R-HSA-8939236;Reactome: R-HSA-1358803;Reactome: R-HSA-2979096;Reactome: R-HSA-6781827;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-9646399;Reactome: R-HSA-2408557;Reactome: R-HSA-8849469;Reactome: R-HSA-2559580;Reactome: R-HSA-5689896;Reactome: R-HSA-936964;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1236382;Reactome: R-HSA-975957;Reactome: R-HSA-5668541;Reactome: R-HSA-5656169;Reactome: R-HSA-209543;Reactome: R-HSA-983168;Reactome: R-HSA-3785653;Reactome: R-HSA-9615710;Reactome: R-HSA-975144;Reactome: R-HSA-975956;Reactome: R-HSA-5654733;Reactome: R-HSA-8941858;Reactome: R-HSA-445989;Reactome: R-HSA-209560;Reactome: R-HSA-2691232;Reactome: R-HSA-400253;Reactome: R-HSA-1253288;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-977225;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5696397;Reactome: R-HSA-9013507;Reactome: R-HSA-5687128;Reactome: R-HSA-912631;Reactome: R-HSA-9613829;Reactome: R-HSA-917729;Reactome: R-HSA-6804760;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-2559582;Reactome: R-HSA-5693565;Reactome: R-HSA-8951664;Reactome: R-HSA-69231;Reactome: R-HSA-937072;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-72706;Reactome: R-HSA-8876493;Reactome: R-HSA-5693607;Reactome: R-HSA-9645460;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-182971;Reactome: R-HSA-5675221;Reactome: R-HSA-2559585;Reactome: R-HSA-156827;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-2173795;Reactome: R-HSA-1234176;Reactome: R-HSA-5685942;Reactome: R-HSA-450302;Reactome: R-HSA-8863795;Reactome: R-HSA-937042;Reactome: R-HSA-69541;Reactome: R-HSA-9633012;Reactome: R-HSA-4641263;Reactome: R-HSA-72689;Reactome: R-HSA-4641257;Reactome: R-HSA-6791226;Reactome: R-HSA-5689603;Reactome: R-HSA-192823;Reactome: R-HSA-8875360;Reactome: R-HSA-5689877;Reactome: R-HSA-5684264;Reactome: R-HSA-5357956;Reactome: R-HSA-68827;Reactome: R-HSA-5696400;Reactome: R-HSA-2173796;Reactome: R-HSA-8948751;Reactome: R-HSA-156902;Reactome: R-HSA-6804757;Reactome: R-HSA-382556;Reactome: R-HSA-9014325;Reactome: R-HSA-205043;Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-975110;Reactome: R-HSA-9604323;Reactome: R-HSA-5696394;Reactome: R-HSA-68949;Reactome: R-HSA-2565942;Reactome: R-HSA-936440;Reactome: R-HSA-5654732;Reactome: R-HSA-174048;Reactome: R-HSA-2122947;Reactome: R-HSA-2173788;Reactome: R-HSA-5654727;Reactome: R-HSA-901032;Reactome: R-HSA-9033241;Reactome: R-HSA-6804756;Reactome: R-HSA-1295596;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-975163;Reactome: R-HSA-5610783;Reactome: R-HSA-2122948;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5357905;Reactome: R-HSA-937041;Reactome: R-HSA-110312;Reactome: R-HSA-174490;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-1799339;Reactome: R-HSA-162588;Reactome: R-HSA-2173791;Reactome: R-HSA-5696395;Reactome: R-HSA-179409;Reactome: R-HSA-3134975;Reactome: R-HSA-917937;Reactome: R-HSA-8939902;Reactome: R-HSA-168638;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-2644606;Reactome: R-HSA-6783310;Reactome: R-HSA-450408;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-2894862;Reactome: R-HSA-1169408;Reactome: R-HSA-3322077;Reactome: R-HSA-5610780;Reactome: R-HSA-8856828;Reactome: R-HSA-201681	"Cargo recognition for clathrin-mediated endocytosis";"Deactivation of the beta-catenin transactivating complex";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"TICAM1-dependent activation of IRF3/IRF7";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of RAS by GAPs";"Regulation of necroptotic cell death";"Metalloprotease DUBs";"IRAK1 recruits IKK complex";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Stimuli-sensing channels";"TICAM1, RIP1-mediated IKK complex recruitment";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Modulation by Mtb of host immune system";"Hedgehog ligand biogenesis";"Assembly Of The HIV Virion";"Pink/Parkin Mediated Mitophagy";"Eukaryotic Translation Termination";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of FGFR1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Regulation of PTEN localization";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of ERBB2:ERBB3 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Aggrephagy";"Selenocysteine synthesis";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Oxidative Stress Induced Senescence";"Ovarian tumor domain proteases";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TNFR2 non-canonical NF-kB pathway";"Termination of translesion DNA synthesis";"p75NTR recruits signalling complexes";"Antigen processing: Ubiquitination & Proteasome degradation";"Myoclonic epilepsy of Lafora";"Late endosomal microautophagy";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Negative regulation of FGFR4 signaling";"Regulation of RUNX3 expression and activity";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NF-kB is activated and signals survival";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Circadian Clock";"Downregulation of ERBB4 signaling";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Amyloid fiber formation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"MAPK6/MAPK4 signaling";"Regulation of signaling by CBL";"Chaperone Mediated Autophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of TP53 Activity through Methylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Senescence-Associated Secretory Phenotype (SASP)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Neddylation";"Cyclin D associated events in G1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"GTP hydrolysis and joining of the 60S ribosomal subunit";"InlA-mediated entry of Listeria monocytogenes into host cells";"Processing of DNA double-strand break ends";"Alpha-protein kinase 1 signaling pathway";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"EGFR downregulation";"Negative regulation of MAPK pathway";"Oncogene Induced Senescence";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HDR through Homologous Recombination (HRR)";"activated TAK1 mediates p38 MAPK activation";"Downregulation of ERBB2 signaling";"IRAK2 mediated activation of TAK1 complex";"Stabilization of p53";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of FZD by ubiquitination";"Formation of a pool of free 40S subunits";"Degradation of AXIN";"Major pathway of rRNA processing in the nucleolus and cytosol";"UCH proteinases";"Viral mRNA Translation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Josephin domain DUBs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TNFR1-induced NFkappaB signaling pathway";"CDT1 association with the CDC6:ORC:origin complex";"Dual Incision in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of PTEN stability and activity";"Peptide chain elongation";"Regulation of TP53 Degradation";"ABC-family proteins mediated transport";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NRIF signals cell death from the nucleus";"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Negative regulation of NOTCH4 signaling";"DNA Damage Recognition in GG-NER";"Orc1 removal from chromatin";"Regulation of PLK1 Activity at G2/M Transition";"Negative regulators of DDX58/IFIH1 signaling";"Negative regulation of FGFR3 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"NOTCH1 Intracellular Domain Regulates Transcription";"Downregulation of TGF-beta receptor signaling";"Negative regulation of FGFR2 signaling";"ER Quality Control Compartment (ERQC)";"Peroxisomal protein import";"Regulation of TP53 Activity through Phosphorylation";"Spry regulation of FGF signaling";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of GLI2 by the proteasome";"Activated NOTCH1 Transmits Signal to the Nucleus";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of TNFR1 signaling";"IKK complex recruitment mediated by RIP1";"Translesion synthesis by REV1";"Membrane binding and targetting of GAG proteins";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"SRP-dependent cotranslational protein targeting to membrane";"Budding and maturation of HIV virion";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Formation of Incision Complex in GG-NER";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of innate immune responses to cytosolic DNA";"Iron uptake and transport";"Regulation of RUNX2 expression and activity";"NOD1/2 Signaling Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Fanconi Anemia Pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"ISG15 antiviral mechanism";"Glycogen synthesis";"Degradation of GLI1 by the proteasome";"Clathrin-mediated endocytosis";"TCF dependent signaling in response to WNT"
XP_050038409.1	14	Reactome: R-HSA-434316;MetaCyc: PWY-7039;Reactome: R-HSA-4086398;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-399997;Reactome: R-HSA-500657;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"Ca2+ pathway";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion";"Presynaptic function of Kainate receptors";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"PLC beta mediated events";"Phosphatidylinositol signaling system"
XP_050049368.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050040792.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_050043606.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045875.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050042108.1	24	Reactome: R-HSA-5621575;KEGG: 04150+2.7.11.11;Reactome: R-HSA-8963896;Reactome: R-HSA-5687128;Reactome: R-HSA-8853659;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-9634600;Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-9010642;Reactome: R-HSA-111931;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-4420097;Reactome: R-HSA-422356;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-392517;Reactome: R-HSA-163560;Reactome: R-HSA-5610785;Reactome: R-HSA-432040	"CD209 (DC-SIGN) signaling";"mTOR signaling pathway";"HDL assembly";"MAPK6/MAPK4 signaling";"RET signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"ROBO receptors bind AKAP5";"PKA-mediated phosphorylation of CREB";"DARPP-32 events";"Hedgehog 'off' state";"VEGFA-VEGFR2 Pathway";"Regulation of insulin secretion";"PKA activation";"PKA activation in glucagon signalling";"Rap1 signalling";"Triglyceride catabolism";"GLI3 is processed to GLI3R by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_050042093.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050047047.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050050338.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050037618.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_050032773.1	31	Reactome: R-HSA-75105;MetaCyc: PWY-8012;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-7746;MetaCyc: PWY-6799;MetaCyc: PWY-7663;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-6113;MetaCyc: PWY-5147;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-6282;MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-6519;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWYG-321;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-7723;MetaCyc: PWY-4381;MetaCyc: PWY-5994;MetaCyc: PWY-8049	"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis I (plants)";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis"
XP_050033801.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050044240.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_050031701.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_050051925.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_050022742.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050027388.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050026012.1	4	KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004	"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I"
XP_050035322.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_050033672.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050023775.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050042050.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050046822.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050049952.1	14	Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696397	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Polymerase switching";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_050047993.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_050035980.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295	"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation"
XP_050032745.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045768.1	2	Reactome: R-HSA-210746;Reactome: R-HSA-210745	"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells";"Regulation of gene expression in beta cells"
XP_050039444.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050025376.1	11	Reactome: R-HSA-388841;Reactome: R-HSA-389948;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-912694;Reactome: R-HSA-909733;Reactome: R-HSA-114604;Reactome: R-HSA-877312;Reactome: R-HSA-512988;Reactome: R-HSA-432142;Reactome: R-HSA-9008059	"Costimulation by the CD28 family";"PD-1 signaling";"Signal regulatory protein family interactions";"PECAM1 interactions";"Regulation of IFNA signaling";"Interferon alpha/beta signaling";"GPVI-mediated activation cascade";"Regulation of IFNG signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Platelet sensitization by LDL";"Interleukin-37 signaling"
XP_050037521.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050044079.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_050051243.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050042219.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_050045040.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_050051440.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_050041079.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050038122.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050027257.1	3	Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_050033402.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050030755.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_050043076.1	11	MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7124;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-6549	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"L-glutamine biosynthesis III"
XP_050040962.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_050044524.1	10	Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes"
XP_050043436.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050024359.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_050034169.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050051748.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050042678.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_050029754.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_050032317.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050049918.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050027779.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050040705.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050024082.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050025248.1	42	Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-73728;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214847;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-9616222;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-5693565;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582	"Meiotic recombination";"RMTs methylate histone arginines";"DNA methylation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Opening";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"HCMV Early Events";"Oxidative Stress Induced Senescence";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"Transcriptional regulation of granulopoiesis";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"Amyloid fiber formation";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)"
XP_050047422.1	25	Reactome: R-HSA-8939247;Reactome: R-HSA-8951911;Reactome: R-HSA-8939246;Reactome: R-HSA-8939256;Reactome: R-HSA-8931987;Reactome: R-HSA-9018519;Reactome: R-HSA-8941326;Reactome: R-HSA-8941333;Reactome: R-HSA-8936459;Reactome: R-HSA-8935964;Reactome: R-HSA-8878166;Reactome: R-HSA-8941858;Reactome: R-HSA-8941284;Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-8939236;Reactome: R-HSA-8877330;Reactome: R-HSA-8940973;Reactome: R-HSA-8941332;Reactome: R-HSA-8939902;Reactome: R-HSA-8951936;Reactome: R-HSA-8949275;Reactome: R-HSA-9616222;Reactome: R-HSA-8934593;Reactome: R-HSA-8939245	"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates estrogen receptor mediated transcription";"Estrogen-dependent gene expression";"RUNX2 regulates bone development";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates expression of components of tight junctions";"Transcriptional regulation by RUNX2";"Regulation of RUNX3 expression and activity";"RUNX2 regulates chondrocyte maturation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates genes involved in cell migration";"Regulation of RUNX2 expression and activity";"RUNX3 regulates p14-ARF";"RUNX3 Regulates Immune Response and Cell Migration";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in BCR signaling"
XP_050050761.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050037431.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
XP_050036384.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050051792.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_050044866.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050048539.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050039690.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050023964.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050052227.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050040309.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050038791.1	7	Reactome: R-HSA-198323;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214	"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs"
XP_050031872.1	9	Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18	"Glutathione conjugation";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450"
XP_050040632.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050049472.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_050040671.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation"
XP_050043127.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_050038602.1	26	Reactome: R-HSA-3214847;Reactome: R-HSA-9614657;Reactome: R-HSA-400253;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-5621575;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-9617629	"HATs acetylate histones";"FOXO-mediated transcription of cell death genes";"Circadian Clock";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"PPARA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"CD209 (DC-SIGN) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation"
XP_050044749.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_050029992.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050045337.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050036138.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656	"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry"
XP_050050134.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050026181.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050043613.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050041727.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050024518.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-5619107	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_050044943.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050049681.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050036029.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050044009.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050052571.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050024263.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050046724.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050052316.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050047862.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050027752.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050040014.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050026428.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050049711.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050041248.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050042106.1	24	Reactome: R-HSA-8853659;Reactome: R-HSA-8963896;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-5621575;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163560;Reactome: R-HSA-164378;Reactome: R-HSA-392517;Reactome: R-HSA-163615;Reactome: R-HSA-5610785;Reactome: R-HSA-432040;Reactome: R-HSA-5610780;Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-4420097;Reactome: R-HSA-5610787;Reactome: R-HSA-111931;Reactome: R-HSA-180024;Reactome: R-HSA-9010642;Reactome: R-HSA-5610783	"RET signaling";"HDL assembly";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"CD209 (DC-SIGN) signaling";"mTOR signaling pathway";"Triglyceride catabolism";"PKA activation in glucagon signalling";"Rap1 signalling";"PKA activation";"GLI3 is processed to GLI3R by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins";"Degradation of GLI1 by the proteasome";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"VEGFA-VEGFR2 Pathway";"Hedgehog 'off' state";"PKA-mediated phosphorylation of CREB";"DARPP-32 events";"ROBO receptors bind AKAP5";"Degradation of GLI2 by the proteasome"
XP_050029055.1	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050041989.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_050043308.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050039235.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700	"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_050031346.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050039311.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050052091.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050037789.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050039873.1	5	MetaCyc: PWY-7282;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_050034885.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050025916.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_050030327.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050040152.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050043040.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_050044923.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050044705.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050036163.1	9	KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086;Reactome: R-HSA-3371599	"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency"
XP_050026269.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_050024165.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901	"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs"
XP_050033404.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_050025646.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050042233.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050027889.1	7	Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_050040288.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050034868.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050025366.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050031793.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_050033836.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050026797.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050023957.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050045373.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_050039550.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_050024467.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050051801.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050051840.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050033787.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050045137.1	7	MetaCyc: PWY-8088;MetaCyc: PWY-2941;MetaCyc: PWY-2942;Reactome: R-HSA-389661;KEGG: 00300+4.3.3.7;KEGG: 00261+4.3.3.7;MetaCyc: PWY-5097	"Dipicolinate biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"Glyoxylate metabolism and glycine degradation";"Lysine biosynthesis";"Monobactam biosynthesis";"L-lysine biosynthesis VI"
XP_050027249.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050046920.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050029751.1	31	MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6519;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-7664;MetaCyc: PWY-6799;MetaCyc: PWY-7663;Reactome: R-HSA-163765;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-4381;MetaCyc: PWY-7723;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5973;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-5142	"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bacterial bioluminescence";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Cis-vaccenate biosynthesis";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway"
XP_050024858.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050028236.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975	"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA"
XP_050046469.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_050039876.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050049036.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_050026053.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050049776.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs"
XP_050031595.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050037572.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation"
XP_050052544.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050027477.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050026259.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_050033857.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050042719.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-5678771;Reactome: R-HSA-382556	"PPARA activates gene expression";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"ABC-family proteins mediated transport"
XP_050040261.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-5872;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;MetaCyc: PWY-6978;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5855	"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)"
XP_050030732.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050044540.1	9	Reactome: R-HSA-418594;Reactome: R-HSA-174577;Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-6798695;Reactome: R-HSA-198933;Reactome: R-HSA-381426;Reactome: R-HSA-977606;Reactome: R-HSA-173736	"G alpha (i) signalling events";"Activation of C3 and C5";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"Neutrophil degranulation";"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of Complement cascade";"Alternative complement activation"
XP_050046807.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050051893.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050050526.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050039454.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-6782135	"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER"
XP_050052374.1	4	KEGG: 00340+4.3.1.3;MetaCyc: PWY-5030;Reactome: R-HSA-70921;MetaCyc: PWY-5028	"Histidine metabolism";"L-histidine degradation III";"Histidine catabolism";"L-histidine degradation II"
XP_050044890.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050024603.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050034675.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050040419.1	8	MetaCyc: PWY-7717;MetaCyc: PWY-7733;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-5651;MetaCyc: PWY-6309	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxyquinaldate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_050051418.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050035978.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases Activate Formins"
XP_050033321.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen degradation";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures"
XP_050034396.1	4	Reactome: R-HSA-1483191;Reactome: R-HSA-163560;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Triglyceride catabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050027594.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050045444.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9018519;Reactome: R-HSA-983231;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886	"Regulation of PTEN gene transcription";"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_050038149.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_050050096.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050026890.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050025763.1	7	Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_050034255.1	15	MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171	"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Pyruvate metabolism";"Glycolysis"
XP_050038766.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_050044574.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050040052.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_050036586.1	5	Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16	"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation"
XP_050029905.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050041114.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050025920.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_050037432.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
XP_050041163.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050030424.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes"
XP_050032011.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050026104.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050051806.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050040139.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050041734.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050051937.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050045593.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050033582.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050051136.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050023147.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050037103.1	5	Reactome: R-HSA-111464;Reactome: R-HSA-111469;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-9627069	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity"
XP_050039381.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220	"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases Activate Formins"
XP_050024175.1	9	Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955	"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Platelet degranulation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050024349.1	4	Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-3232142;Reactome: R-HSA-983168	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"SUMOylation of ubiquitinylation proteins";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050050773.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050050098.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050039607.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050023798.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050023728.1	32	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription of the HIV genome"
XP_050049087.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206302	"HS-GAG degradation";"CS/DS degradation";"MPS I - Hurler syndrome"
XP_050026519.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432722	"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis"
XP_050051509.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050024649.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050046601.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050037090.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_050039464.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_050029735.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050044096.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_050032085.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050044802.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050050651.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050045360.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050031482.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050035831.1	18	MetaCyc: PWY-6620;Reactome: R-HSA-73621;Reactome: R-HSA-73614;MetaCyc: PWY-7179;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;MetaCyc: PWY-4202;MetaCyc: PWY-6611;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-6609	"Guanine and guanosine salvage";"Pyrimidine catabolism";"Pyrimidine salvage";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III"
XP_050026164.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050029885.1	1	Reactome: R-HSA-166208	"mTORC1-mediated signalling"
XP_050032233.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050048384.1	9	Reactome: R-HSA-438066;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001	"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade"
XP_050030242.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+"
XP_050039592.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050026974.1	8	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo"
XP_050049887.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050047664.1	2	Reactome: R-HSA-69231;Reactome: R-HSA-8934593	"Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity"
XP_050034545.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050042638.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050040020.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050043785.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050048817.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050035948.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050044489.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208	"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling"
XP_050027815.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050037143.1	12	MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation"
XP_050029205.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050045461.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050042129.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050051419.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050036809.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_050023111.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050034171.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_050042140.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050045599.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050033134.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7	"Betanidin degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis"
XP_050035198.1	12	MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417	"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_050034362.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050025423.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050039624.1	6	Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_050039651.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050040045.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050030254.1	5	Reactome: R-HSA-9627069;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"Formation of apoptosome"
XP_050040346.1	5	MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6	"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism"
XP_050031170.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050052149.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050039700.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_050043402.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis"
XP_050050203.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism"
XP_050023588.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050050140.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050027470.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050033167.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050025281.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050048032.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-110362;Reactome: R-HSA-2173795	"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair";"Downregulation of SMAD2/3:SMAD4 transcriptional activity"
XP_050031140.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_050046869.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050048157.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050049366.1	9	KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52	"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_050023668.1	1	Reactome: R-HSA-5624138	"Trafficking of myristoylated proteins to the cilium"
XP_050048645.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050037187.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_050022722.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050036675.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)"
XP_050036670.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050023408.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050041409.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050044383.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050044239.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_050027589.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050036372.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050038630.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2467813	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids"
XP_050041610.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050029434.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050040013.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050050042.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050026876.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050034834.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050037455.1	14	Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4	"Synthesis of PC";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PE";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism"
XP_050022817.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050052173.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050040307.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050051417.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050029602.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050046030.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050030443.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050045541.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050048818.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_050025974.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050029438.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050035113.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050050866.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_050030834.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050047860.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050026169.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050024314.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050027499.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050039211.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050027180.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050040300.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_050045408.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050043788.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049224.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050044188.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050023203.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050042467.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_050052179.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050031204.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050051480.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050025006.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050050303.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050047045.1	3	MetaCyc: PWY-7979;KEGG: 00515+2.7.1.183;Reactome: R-HSA-5173105	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation"
XP_050050240.1	6	MetaCyc: PWY-6364;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_050044532.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050032705.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050045004.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050039130.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_050029831.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243	"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050032919.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050026887.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis"
XP_050042669.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290	"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_050034326.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050030876.1	4	Reactome: R-HSA-174577;Reactome: R-HSA-375276;Reactome: R-HSA-977606;Reactome: R-HSA-418594	"Activation of C3 and C5";"Peptide ligand-binding receptors";"Regulation of Complement cascade";"G alpha (i) signalling events"
XP_050038737.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050046955.1	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_050027560.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050043542.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050025483.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050024679.1	8	Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-191273	"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis"
XP_050041240.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050038213.1	42	Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-3214847;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-5693565;Reactome: R-HSA-9616222;Reactome: R-HSA-5693571;Reactome: R-HSA-977225;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-427389	"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"HATs acetylate histones";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation of granulopoiesis";"Nonhomologous End-Joining (NHEJ)";"Amyloid fiber formation";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"RMTs methylate histone arginines";"DNA methylation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"HDACs deacetylate histones";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050029925.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050051624.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_050044211.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045011.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050031894.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050046798.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050035977.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050041945.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_050023197.1	7	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis"
XP_050051831.1	6	MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;Reactome: R-HSA-446199;MetaCyc: PWY-922	"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I"
XP_050046970.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050033591.1	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
XP_050040207.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050049985.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_050041738.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050048801.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-141430	"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_050044355.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050029405.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_050023772.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050050657.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620912	"Hedgehog 'off' state";"Anchoring of the basal body to the plasma membrane"
XP_050041332.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050034504.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050052462.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050041439.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050026075.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050036812.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050040301.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_050025944.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050038344.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism"
XP_050044612.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050046735.1	24	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-6811436	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Kinesins";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050049167.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050037630.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050052051.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_050029917.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-180024	"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"DARPP-32 events"
XP_050029801.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_050025243.1	42	Reactome: R-HSA-201722;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-9616222;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-977225;Reactome: R-HSA-5693565;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-3214847;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-3214815;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-1221632;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-5617472;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-5334118;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-73728;Reactome: R-HSA-5625886	"Formation of the beta-catenin:TCF transactivating complex";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Transcriptional regulation of granulopoiesis";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"Amyloid fiber formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"HATs acetylate histones";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"HDACs deacetylate histones";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Meiotic synapsis";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RMTs methylate histone arginines";"Meiotic recombination";"DNA methylation";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_050040512.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050034158.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_050048361.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs"
XP_050045588.1	12	Reactome: R-HSA-1912408;Reactome: R-HSA-73762;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695	"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Transcription Initiation";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_050051990.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050038829.1	5	KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_050038468.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050051487.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050042713.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050035848.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050036207.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)"
XP_050044396.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_050037016.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050037263.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050026482.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_050052231.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8948751	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity"
XP_050046537.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050038707.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050043790.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050048425.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050025364.1	8	MetaCyc: PWY-7193;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7181;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage"
XP_050029076.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050029738.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050035933.1	34	Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-9639288	"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1"
XP_050036156.1	52	Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236	"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_050045421.1	6	KEGG: 00670+2.1.2.5;KEGG: 00340+2.1.2.5;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5030;MetaCyc: PWY-5497;Reactome: R-HSA-70921	"One carbon pool by folate";"Histidine metabolism";"One carbon pool by folate";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Histidine catabolism"
XP_050036540.1	11	KEGG: 00670+2.1.1.13;KEGG: 00450+2.1.1.13;Reactome: R-HSA-196741;MetaCyc: PWY-7977;Reactome: R-HSA-156581;Reactome: R-HSA-3359467;MetaCyc: PWY-2201;Reactome: R-HSA-3359469;Reactome: R-HSA-1614635;KEGG: 00270+2.1.1.13;MetaCyc: PWY-3841	"One carbon pool by folate";"Selenocompound metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"L-methionine biosynthesis IV (archaea)";"Methylation";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Folate transformations I";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Sulfur amino acid metabolism";"Cysteine and methionine metabolism";"Folate transformations II (plants)"
XP_050045235.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050023059.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050034678.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050034459.1	3	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695	"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Neutrophil degranulation"
XP_050031025.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_050049205.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_050024914.1	4	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_050032518.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050035066.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050040999.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050050018.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050050142.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050036750.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_050039779.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050052249.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050043180.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050052743.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_050024207.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050027722.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050044448.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050032992.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050028107.1	3	Reactome: R-HSA-5578995;KEGG: 00983+2.1.1.67;Reactome: R-HSA-156581	"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Drug metabolism - other enzymes";"Methylation"
XP_050046028.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_050036820.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050052552.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050041502.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
XP_050032509.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
YP_010283871.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050048401.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050045479.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050038736.1	4	Reactome: R-HSA-3359478;Reactome: R-HSA-196741;Reactome: R-HSA-71032;Reactome: R-HSA-3359475	"Defective MUT causes methylmalonic aciduria mut type";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Propionyl-CoA catabolism";"Defective MMAA causes methylmalonic aciduria type cblA"
XP_050034886.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050046377.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050029056.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842	"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II"
XP_050044621.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050051051.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050050734.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050040960.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275	"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation"
XP_050044552.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050047207.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050026674.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050023840.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050026793.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050030821.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050030763.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050048620.1	30	Reactome: R-HSA-8876198;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-389357;Reactome: R-HSA-9634638;Reactome: R-HSA-1358803;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804759;Reactome: R-HSA-211163;Reactome: R-HSA-198323;Reactome: R-HSA-5218920;Reactome: R-HSA-9614399;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69202;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69656;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-389513;Reactome: R-HSA-8948751;Reactome: R-HSA-199418;Reactome: R-HSA-198693;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"RAB GEFs exchange GTP for GDP on RABs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"CD28 dependent PI3K/Akt signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of ERBB2:ERBB3 signaling";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Association with Co-factors";"AKT-mediated inactivation of FOXO1A";"AKT phosphorylates targets in the cytosol";"VEGFR2 mediated vascular permeability";"Regulation of localization of FOXO transcription factors";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Cyclin E associated events during G1/S transition";"Relaxin signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"RUNX2 regulates genes involved in cell migration";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Regulation of TP53 Activity through Acetylation";"CTLA4 inhibitory signaling";"Regulation of PTEN stability and activity";"Negative regulation of the PI3K/AKT network";"AKT phosphorylates targets in the nucleus";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_050030080.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050039015.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
XP_050025370.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050046967.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050030426.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050042565.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050041376.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_050043146.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050046051.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050049310.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049144.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050025621.1	7	KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid"
XP_050048217.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050049076.1	13	MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384	"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_050044626.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050031360.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-3214815	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones"
XP_050048721.1	57	Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-532668;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978	"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_050049873.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050033946.1	6	KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1	"Pentose and glucuronate interconversions";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_050041128.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050047269.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050029770.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050048456.1	17	KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;Reactome: R-HSA-200425;Reactome: R-HSA-196780;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2	"Fatty acid biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Carnitine metabolism";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism"
XP_050034094.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050032867.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_050029387.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050043179.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050026806.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050048201.1	15	Reactome: R-HSA-9665251;Reactome: R-HSA-5637810;Reactome: R-HSA-9665233;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-9665250;Reactome: R-HSA-9664565;Reactome: R-HSA-9652282;Reactome: R-HSA-9665244;Reactome: R-HSA-9665249;Reactome: R-HSA-8863795;Reactome: R-HSA-9665246;Reactome: R-HSA-9665245	"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2 KD Mutants";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to afatinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to tesevatinib"
XP_050030513.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_050023928.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050040922.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050043833.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050046392.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_050044656.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050044712.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050045458.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Ion channel transport"
XP_050024935.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490	"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation"
XP_050040056.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050029818.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050034682.1	2	Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_050036567.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978	"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_050035320.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_050045443.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050047044.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050035983.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050030639.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_050042787.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050047839.1	8	MetaCyc: PWY-66;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-5740;KEGG: 00520+4.2.1.47	"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-colitose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050038647.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_050034452.1	4	KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.9	"Galactose metabolism";"Starch and sucrose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis"
XP_050051072.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_050038626.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050045364.1	7	MetaCyc: PWY-8026;KEGG: 00100+1.3.1.70;Reactome: R-HSA-9022692;MetaCyc: PWY-6074;Reactome: R-HSA-191273;MetaCyc: PWY-2541;MetaCyc: PWY-7154	"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Regulation of MECP2 expression and activity";"Zymosterol biosynthesis";"Cholesterol biosynthesis";"Phytosterol biosynthesis (plants)";"Ergosterol biosynthesis II"
XP_050049823.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050047864.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050047633.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-425986	"Stimuli-sensing channels";"Sodium/Proton exchangers"
XP_050025496.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050023845.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050032235.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-174430	"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation"
XP_050049708.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050024742.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050042212.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050047028.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050022889.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050048247.1	9	KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842	"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification II"
XP_050031848.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050024282.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050045363.1	7	MetaCyc: PWY-8026;KEGG: 00100+1.3.1.70;Reactome: R-HSA-9022692;MetaCyc: PWY-6074;Reactome: R-HSA-191273;MetaCyc: PWY-7154;MetaCyc: PWY-2541	"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Regulation of MECP2 expression and activity";"Zymosterol biosynthesis";"Cholesterol biosynthesis";"Ergosterol biosynthesis II";"Phytosterol biosynthesis (plants)"
XP_050038621.1	9	KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2	"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis"
XP_050049407.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050042866.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_050023140.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050042777.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050029883.1	1	Reactome: R-HSA-166208	"mTORC1-mediated signalling"
XP_050050506.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050050644.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050041250.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050052115.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050041659.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050023718.1	33	Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638	"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins"
XP_050027934.1	4	KEGG: 00232+2.3.1.5;KEGG: 00983+2.3.1.5;Reactome: R-HSA-156582;KEGG: 00633+2.3.1.5	"Caffeine metabolism";"Drug metabolism - other enzymes";"Acetylation";"Nitrotoluene degradation"
XP_050047042.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050038896.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050041676.1	4	Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;MetaCyc: PWY-7250	"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_050035990.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050039553.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050028050.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050023532.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050041695.1	10	MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10	"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Butanoate metabolism"
XP_050051749.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050028068.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050026113.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050039370.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050052827.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050051472.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050049826.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_050031300.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-977606;Reactome: R-HSA-375276;Reactome: R-HSA-174577	"G alpha (i) signalling events";"Regulation of Complement cascade";"Peptide ligand-binding receptors";"Activation of C3 and C5"
XP_050044777.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050044748.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050043177.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050040199.1	58	Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5689901;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895	"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Metalloprotease DUBs";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Neddylation";"Defective CFTR causes cystic fibrosis"
XP_050024917.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050045459.1	8	Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Ion channel transport"
XP_050030781.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050047668.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050026843.1	11	Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-205043	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus"
XP_050040511.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050037135.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050042679.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_050048141.1	13	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-2424491;Reactome: R-HSA-2871796;Reactome: R-HSA-202433;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;MetaCyc: PWY-6367;Reactome: R-HSA-9027277;Reactome: R-HSA-2029485;MetaCyc: PWY-7039;MetaCyc: PWY-8052	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling";"FCERI mediated MAPK activation";"Generation of second messenger molecules";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"D-myo-inositol-5-phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis"
XP_050049901.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050039379.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050043924.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-383280;Reactome: R-HSA-9018519;Reactome: R-HSA-400253	"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Nuclear Receptor transcription pathway";"Estrogen-dependent gene expression";"Circadian Clock"
XP_050033999.1	7	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-429947	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Deadenylation of mRNA"
XP_050029824.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944	"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2"
XP_050031027.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050052560.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050032703.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050039081.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_050044078.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050027990.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_050043133.1	4	MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922	"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_050039877.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050034722.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_050052563.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050032607.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050026289.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050024732.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050051183.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050035982.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295	"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation"
XP_050025215.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_050051835.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_050023985.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050038305.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050045471.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050049136.1	9	KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52	"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series"
XP_050030831.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050047314.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050037482.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_050046727.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050045910.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050041997.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69183	"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand"
XP_050022942.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050052309.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_050027558.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050036636.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036	"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II"
XP_050044295.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050046123.1	52	Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-5250924;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-1834949;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884;Reactome: R-HSA-674695;Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-6781823;Reactome: R-HSA-167242;Reactome: R-HSA-6782135	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"B-WICH complex positively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Formation of TC-NER Pre-Incision Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Dual incision in TC-NER"
XP_050040293.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050048220.1	9	MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18	"Glutathione-mediated detoxification II";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism"
XP_050035917.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050038668.1	4	KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050044788.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050052127.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050044865.1	3	Reactome: R-HSA-1222556;Reactome: R-HSA-1300642;Reactome: R-HSA-6798695	"ROS and RNS production in phagocytes";"Sperm Motility And Taxes";"Neutrophil degranulation"
XP_050043539.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050029781.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050045038.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_050049165.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050037114.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050029581.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_050050691.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952	"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions"
XP_050039998.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050047089.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050039324.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050051758.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_050033504.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_050026049.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_050038777.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050044171.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_050047528.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050031139.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_050044999.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050049710.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050031520.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050028519.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050033908.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050044692.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050025603.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_050052117.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050048061.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050049197.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_050042900.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050031480.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050047333.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050047041.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050041996.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69183	"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand"
XP_050030475.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_050023265.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050042290.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050046081.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050042414.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050034256.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_050035211.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050036169.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050036236.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050024400.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050047982.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050052296.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050029265.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050031911.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_050045177.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050047470.1	5	KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis"
XP_050034614.1	11	MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6118;KEGG: 00340+2.1.1.22;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;Reactome: R-HSA-70921;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385	"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Histidine metabolism";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Histidine catabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_050031697.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050039397.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050036692.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050035532.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050023664.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050051420.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050026191.1	1	MetaCyc: PWY-7883	"Anhydromuropeptides recycling II"
XP_050049819.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050035169.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_050036607.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_050026059.1	10	MetaCyc: PWY-6362;MetaCyc: PWY-6554;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;MetaCyc: PWY-6361;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_050028873.1	9	MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2	"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism"
XP_050039902.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050033002.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
XP_050040338.1	15	Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-174084	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_050035853.1	1	Reactome: R-HSA-5357905	"Regulation of TNFR1 signaling"
XP_050039377.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050030329.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050048410.1	5	MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;Reactome: R-HSA-6798695	"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"Pentose phosphate pathway";"Neutrophil degranulation"
XP_050048413.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis"
XP_050032601.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050036261.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_050034246.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_050044966.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050023028.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050035921.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050049383.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_050023597.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050027177.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050047703.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050051383.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050032823.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_050032634.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050038883.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050052372.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling"
XP_050035966.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050038814.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050034674.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050030681.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport"
XP_050049454.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050026573.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_050045009.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050030792.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050044803.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050040247.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050040214.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183	"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_050033614.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050047955.1	7	Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050024840.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148	"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050031108.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050039827.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050037396.1	11	MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268	"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_050045776.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050051673.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050038776.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050052585.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050023244.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050042169.1	13	Reactome: R-HSA-6798695;Reactome: R-HSA-2206308;MetaCyc: PWY-6807;Reactome: R-HSA-4341670;Reactome: R-HSA-2022857;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-2024096;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Neutrophil degranulation";"MPS IV - Morquio syndrome B";"Xyloglucan degradation II (exoglucanase)";"Defective NEU1 causes sialidosis";"Keratan sulfate degradation";"Galactose metabolism";"Sialic acid metabolism";"HS-GAG degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_050025644.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050042437.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_050051332.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_050044971.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050047718.1	4	KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050044888.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050038369.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050034633.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050026292.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050049098.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050030479.1	13	KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101	"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"CS/DS degradation"
XP_050023767.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050023172.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport"
XP_050047265.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050031256.1	12	MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_050045935.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050031016.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_050023625.1	11	Reactome: R-HSA-8943724;Reactome: R-HSA-8862803;Reactome: R-HSA-2871796;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-5687128;Reactome: R-HSA-450341;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580	"Regulation of PTEN gene transcription";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FCERI mediated MAPK activation";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MAPK6/MAPK4 signaling";"Activation of the AP-1 family of transcription factors";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence"
XP_050030785.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050050511.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050046071.1	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
XP_050025489.1	10	MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_050037172.1	18	MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086	"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_050044453.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_050029429.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050050898.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050047816.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050050701.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-6802955	"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050045057.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050045710.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_050050791.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050023596.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050029419.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050050865.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_050039242.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_050042079.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-1989781	"Circadian Clock";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression"
XP_050037105.1	3	Reactome: R-HSA-5173214;Reactome: R-HSA-189085;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Digestion of dietary carbohydrate";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050039310.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049086.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-390696;Reactome: R-HSA-416482	"G alpha (q) signalling events";"Adrenoceptors";"G alpha (12/13) signalling events"
XP_050026988.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050039837.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050038832.1	5	KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism"
XP_050023640.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050034503.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050050483.1	6	KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation"
XP_050025358.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050040427.1	29	Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-113418	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex"
XP_050034156.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050052037.1	8	KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-4661;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372;MetaCyc: PWY-6664	"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis"
XP_050034506.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-110314	"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050030162.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050039558.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050032293.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation"
XP_050029506.1	6	MetaCyc: PWY-5269;MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Synthesis of PA";"Synthesis of PG"
XP_050037559.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050036189.1	4	Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462	"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_050046039.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050046729.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050034737.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050050940.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_050023058.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050035570.1	13	Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52	"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation"
XP_050051507.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050044202.1	4	Reactome: R-HSA-9610379;Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-72203	"HCMV Late Events";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050038432.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050046078.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050030957.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_050047338.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-6811436	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Kinesins";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050045180.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050045647.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050037472.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050052177.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_050023802.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050031422.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050032596.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_050025591.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050044440.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050036629.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050042920.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050027888.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050038635.1	5	KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_050049375.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_050028849.1	5	Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873	"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation"
XP_050024748.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050049902.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050039332.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184	"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_050030943.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050052520.1	4	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation";"Pyrophosphate hydrolysis"
XP_050046122.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050030798.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050031414.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050046058.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050031012.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050038532.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050039223.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_050033494.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050052474.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050044292.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050042814.1	3	Reactome: R-HSA-5678520;Reactome: R-HSA-193368;Reactome: R-HSA-159418	"Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Recycling of bile acids and salts"
XP_050034325.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050025020.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050031324.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050032810.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050032730.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050044010.1	29	Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape"
XP_050033240.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097	"DSCAM interactions";"p38MAPK events";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_050027273.1	4	MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_050027511.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050032756.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050036110.1	13	KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis"
XP_050038110.1	2	KEGG: 00230+3.6.1.66;Reactome: R-HSA-74259	"Purine metabolism";"Purine catabolism"
XP_050034847.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_050047264.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_050034170.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I"
XP_050039336.1	7	Reactome: R-HSA-1483191;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7782;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82	"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism"
XP_050032512.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Ub-specific processing proteases"
XP_050029068.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050040156.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050041740.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050035019.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050050204.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism"
XP_050027708.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050026657.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050048350.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_050031395.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050046053.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050035845.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050041327.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922	"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Activation of SMO";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium"
XP_050048528.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050039589.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_050043804.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050046467.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_050038206.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050038118.1	5	KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050036580.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_050034883.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050035077.1	8	MetaCyc: PWY-6309;MetaCyc: PWY-5651;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7765;MetaCyc: PWY-7733;MetaCyc: PWY-7717	"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_050034447.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_050027443.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050027134.1	57	Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577	"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Neddylation";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21"
XP_050025689.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050034762.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050036230.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050031529.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050042972.1	14	Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Polymerase switching";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050051516.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050044407.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_050043351.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050039480.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050028210.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050044086.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050034620.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050047794.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050045331.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050034917.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050026981.1	13	KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883	"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II"
XP_050043904.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050039851.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050046710.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050039706.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis"
XP_050031013.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_050043069.1	11	MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7268;MetaCyc: PWY-7124;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42	"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Glutathione metabolism"
XP_050037949.1	3	Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144	"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_050051032.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_050045824.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_050035858.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_050048233.1	9	MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590;MetaCyc: PWY-6842	"Glutathione-mediated detoxification I";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione-mediated detoxification II"
XP_050047029.1	4	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-6811440;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Retrograde transport at the Trans-Golgi-Network";"Insulin processing"
XP_050041325.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418597	"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events"
XP_050051797.1	12	KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-5278;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4	"Sulfur metabolism";"Transport and synthesis of PAPS";"Sulfite oxidation III";"Selenate reduction";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Purine metabolism"
XP_050041080.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050030621.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050025703.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050028241.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events"
XP_050030373.1	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050046316.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049379.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050023811.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050045052.1	12	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167200	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050046692.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050024172.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050050209.1	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346	"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Hedgehog ligand biogenesis"
XP_050052093.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050031350.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050045127.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050043812.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050040029.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050043612.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050023773.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050038557.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050024489.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050027066.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050024142.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050049348.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050036449.1	5	KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_050039445.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050045646.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
XP_050029847.1	4	Reactome: R-HSA-6798695;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Neutrophil degranulation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050026711.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
XP_050027965.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050030659.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050050989.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_050042599.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050044169.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050037503.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050032793.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050044875.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050050508.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050032609.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050032757.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050049774.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050048230.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050033907.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050028637.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050024877.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050048642.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050049859.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_050045668.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050035405.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050044605.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050031020.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_050050869.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050044360.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050041330.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050034536.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_050048472.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050043303.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050043166.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050047220.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050037312.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_050033502.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050051411.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050044613.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050035434.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_050044701.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050031628.1	10	Reactome: R-HSA-4570464;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-4551638;Reactome: R-HSA-4655427;Reactome: R-HSA-3899300;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"SUMOylation of RNA binding proteins";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA methylation proteins";"SUMOylation of transcription cofactors";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_050037855.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166	"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA"
XP_050033136.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050036102.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050047064.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050027723.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050043920.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050030085.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
XP_050036266.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050041973.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050050693.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5576892	"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"RAF activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation"
XP_050036050.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_050044832.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_050038774.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050049582.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050040836.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050035165.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050048389.1	2	Reactome: R-HSA-8934593;Reactome: R-HSA-69231	"Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1"
XP_050023649.1	5	Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-901042	"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle"
XP_050044618.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050045185.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050045660.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733	"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_050040456.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050044582.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050044680.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_050046003.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050042128.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050040904.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_050027119.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050048967.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050044956.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050052545.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050045603.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050022903.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
XP_050041599.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050037743.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050050151.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_050032971.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050049761.1	24	Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"RHO GTPases Activate Formins"
XP_050031901.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050041904.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050046754.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050027845.1	5	Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-2426168	"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_050037110.1	6	Reactome: R-HSA-2408550;Reactome: R-HSA-499943;KEGG: 00480+1.8.1.7;Reactome: R-HSA-3299685;MetaCyc: PWY-4081;Reactome: R-HSA-5628897	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"Glutathione-peroxide redox reactions";"TP53 Regulates Metabolic Genes"
XP_050047740.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_050050138.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050033199.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_050026581.1	7	MetaCyc: PWY-7221;Reactome: R-HSA-6798695;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205	"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes"
XP_050045739.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_050026491.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_050040306.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050044191.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828	"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis"
XP_050051503.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050043194.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050028343.1	6	Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-8950505	"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050041544.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_050024271.1	4	MetaCyc: PWY-5704;KEGG: 00230+3.5.1.5;KEGG: 00791+3.5.1.5;KEGG: 00220+3.5.1.5	"Urea degradation II";"Purine metabolism";"Atrazine degradation";"Arginine biosynthesis"
XP_050037575.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5466	"Justicidin B biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis"
XP_050039986.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_050048914.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050046113.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050051964.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling"
XP_050027320.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_050029404.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050049335.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050052206.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_050049775.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050038993.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050048913.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050027890.1	8	Reactome: R-HSA-4641263;Reactome: R-HSA-5099900;Reactome: R-HSA-4608870;Reactome: R-HSA-8856825;Reactome: R-HSA-373080;Reactome: R-HSA-8856828;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588	"Regulation of FZD by ubiquitination";"WNT5A-dependent internalization of FZD4";"Asymmetric localization of PCP proteins";"Cargo recognition for clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"Clathrin-mediated endocytosis";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation"
XP_050026060.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7338	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_050026883.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-1632852;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Macroautophagy";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases Activate Formins"
XP_050034505.1	10	Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome"
XP_050029433.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050032330.1	17	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050049533.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050023364.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050046345.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-877300	"Interferon alpha/beta signaling";"Interferon gamma signaling"
XP_050050216.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050049293.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050033593.1	2	Reactome: R-HSA-425986;Reactome: R-HSA-2672351	"Sodium/Proton exchangers";"Stimuli-sensing channels"
XP_050048507.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-9028731;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-5673001	"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade"
XP_050049507.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050036508.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050039083.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis"
XP_050045470.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050037150.1	12	MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism"
XP_050042353.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050037560.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050039071.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_050041741.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050043896.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050029166.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050040799.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050042946.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050028628.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050049818.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050039215.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_050035761.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050023869.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050028160.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050041141.1	5	Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi"
XP_050040202.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050045336.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050036268.1	42	Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-5693565;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-3214847;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-3214815;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-73728;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-73772	"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"HATs acetylate histones";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"HDACs deacetylate histones";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Meiotic synapsis";"DNA methylation";"Meiotic recombination";"RMTs methylate histone arginines";"RNA Polymerase I Promoter Escape"
XP_050036164.1	9	Reactome: R-HSA-3371599;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1	"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism"
XP_050042306.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050049556.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050022524.1	3	Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144	"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_050029755.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050042109.1	24	Reactome: R-HSA-163560;Reactome: R-HSA-392517;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-381676;Reactome: R-HSA-9634600;Reactome: R-HSA-163358;Reactome: R-HSA-422356;Reactome: R-HSA-4420097;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-111931;Reactome: R-HSA-9010642;Reactome: R-HSA-5610783;Reactome: R-HSA-8853659;Reactome: R-HSA-5687128;Reactome: R-HSA-8963896;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-5621575;KEGG: 04150+2.7.11.11	"Triglyceride catabolism";"Rap1 signalling";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"PKA-mediated phosphorylation of key metabolic factors";"Regulation of insulin secretion";"VEGFA-VEGFR2 Pathway";"Hedgehog 'off' state";"DARPP-32 events";"PKA-mediated phosphorylation of CREB";"ROBO receptors bind AKAP5";"Degradation of GLI2 by the proteasome";"RET signaling";"MAPK6/MAPK4 signaling";"HDL assembly";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"CD209 (DC-SIGN) signaling";"mTOR signaling pathway"
XP_050034501.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050032822.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_050032256.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050049123.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_050051666.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_050022585.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050037562.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050051600.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050025359.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050034395.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-163560;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Triglyceride catabolism";"Synthesis of PC"
XP_050039213.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050038513.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050027823.1	10	MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061	"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I"
XP_050025956.1	4	MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050040109.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050046084.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050040026.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050036379.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050028344.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane"
XP_050048111.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_050029337.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128	"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling"
XP_050027174.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050034114.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050034971.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158	"Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V"
XP_050035986.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050044597.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_050026082.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_050034433.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050049443.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050024310.1	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050040406.1	12	MetaCyc: PWY-5133;MetaCyc: PWY-5132;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1	"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism"
XP_050042156.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050033751.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_050038584.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050032744.1	2	Reactome: R-HSA-156590;Reactome: R-HSA-9033241	"Glutathione conjugation";"Peroxisomal protein import"
XP_050038895.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-141444	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050025613.1	3	MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_050046966.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050049226.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050032807.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050052258.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841	"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines"
XP_050044488.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
XP_050038560.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_050052032.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_050030430.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-5689880;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_050031207.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050027959.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050039882.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_050049908.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050026888.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050044217.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050052287.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050049421.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050048525.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050028103.1	3	Reactome: R-HSA-156581;KEGG: 00983+2.1.1.67;Reactome: R-HSA-5578995	"Methylation";"Drug metabolism - other enzymes";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)"
XP_050039299.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_050035992.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_050049404.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_050031115.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050026607.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050037095.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_050037470.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050041511.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050034841.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050023674.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399	"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy"
XP_050049411.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050038612.1	9	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050023270.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050027078.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050037649.1	3	Reactome: R-HSA-156581;KEGG: 00983+2.1.1.67;Reactome: R-HSA-5578995	"Methylation";"Drug metabolism - other enzymes";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)"
XP_050050910.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050044780.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050046049.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050023841.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050050041.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050033318.1	57	Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"ER-Phagosome pathway"
XP_050046874.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050033225.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_050034259.1	6	Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52	"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Vitamin B6 metabolism";"Methane metabolism"
XP_050044087.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050042755.1	28	Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-5655862;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5696395;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-3371453;Reactome: R-HSA-3371511;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685942	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Translesion synthesis by POLK";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of Incision Complex in GG-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Regulation of HSF1-mediated heat shock response";"HSF1 activation";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Homologous Recombination (HRR)"
XP_050037646.1	3	KEGG: 00983+2.1.1.67;Reactome: R-HSA-5578995;Reactome: R-HSA-156581	"Drug metabolism - other enzymes";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Methylation"
XP_050044069.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050046065.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_050040341.1	15	Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-8853884	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX"
XP_050049261.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050036238.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050032102.1	13	Reactome: R-HSA-3928663;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"EPHA-mediated growth cone collapse";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"mTOR signaling pathway";"Thermogenesis"
XP_050037070.1	6	KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-6737	"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation III";"Sucrose biosynthesis II";"Starch degradation V"
XP_050046589.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050036416.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050028165.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050048422.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050051415.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050051712.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_050039483.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050048965.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_050048633.1	9	Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-6983	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis"
XP_050036822.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050036246.1	6	Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-2029485	"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis"
XP_050049130.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050032615.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_050048294.1	13	Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"LDL clearance";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis"
XP_050036447.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_050043461.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050049229.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050022909.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050041220.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050052587.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050025344.1	2	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
XP_050031349.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050045605.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050044194.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity"
XP_050035419.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050041726.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050023465.1	4	Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_050038800.1	13	KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7227	"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_050051599.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050036849.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_050049240.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050036395.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050050643.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050027095.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050031208.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050048012.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050049769.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050023196.1	7	MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14	"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine metabolism"
XP_050052756.1	10	MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153	"3-phosphoinositide biosynthesis";"mTOR signaling pathway";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Phosphatidylinositol signaling system"
XP_050033401.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050035554.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050035163.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_050036241.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050048029.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050024286.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050040577.1	8	MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9;MetaCyc: PWY-5651;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-7717;MetaCyc: PWY-7733	"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxyquinaldate biosynthesis"
XP_050036544.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050028231.1	11	Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"DNA replication initiation";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_050049163.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050044278.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050045365.1	7	Reactome: R-HSA-9022692;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.70;MetaCyc: PWY-2541;MetaCyc: PWY-7154;MetaCyc: PWY-6074;Reactome: R-HSA-191273	"Regulation of MECP2 expression and activity";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Phytosterol biosynthesis (plants)";"Ergosterol biosynthesis II";"Zymosterol biosynthesis";"Cholesterol biosynthesis"
XP_050051080.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-166208	"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling"
XP_050042199.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050050239.1	6	MetaCyc: PWY-6362;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_050050470.1	7	Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;MetaCyc: PWY-7039	"Role of phospholipids in phagocytosis";"Synthesis of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule"
XP_050024028.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050049078.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050029648.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050037036.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_050033720.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050046830.1	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
XP_050024092.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050049196.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050052142.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050044525.1	10	Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-163680	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity"
XP_050049198.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_050026483.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_050051504.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050038642.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_050030797.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050046766.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050031168.1	4	KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_050024203.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050047081.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050049728.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050029858.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway"
XP_050038838.1	6	MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077	"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"N-acetyl-D-galactosamine degradation"
XP_050027195.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_050040144.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050041323.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050035882.1	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
XP_050036031.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050050242.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050045218.1	11	KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7206	"Purine metabolism";"Pantothenate and CoA biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_050022747.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050050867.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_050032248.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050040050.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
XP_050027479.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050046148.1	17	Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-69205;Reactome: R-HSA-8953750;Reactome: R-HSA-139915;Reactome: R-HSA-2173796;Reactome: R-HSA-111448;Reactome: R-HSA-113501;Reactome: R-HSA-1538133	"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"G1/S-Specific Transcription";"Transcriptional Regulation by E2F6";"Activation of PUMA and translocation to mitochondria";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activation of NOXA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G0 and Early G1"
XP_050052662.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027140.1	5	Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857	"Neutrophil degranulation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation"
XP_050043586.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050036824.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050039380.1	24	Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295	"Resolution of Sister Chromatid Cohesion";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"MHC class II antigen presentation"
XP_050038764.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_050039086.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis"
XP_050030410.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_050034022.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-110362	"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair"
XP_050045914.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050050603.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050035430.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050033201.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_050033234.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050039591.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_050046821.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_050045827.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_050048257.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_050045000.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050037415.1	11	Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050035427.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050029448.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050034319.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050040143.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_050040347.1	5	KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation"
XP_050052562.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050045574.1	10	MetaCyc: PWY-5895;MetaCyc: PWY-5849;MetaCyc: PWY-5891;MetaCyc: PWY-5890;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5839;MetaCyc: PWY-5892;Reactome: R-HSA-2142789;MetaCyc: PWY-7996;MetaCyc: PWY-5844	"Menaquinol-13 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-10 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-9 biosynthesis"
XP_050045792.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_050050557.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050045970.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050027500.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050039427.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050051363.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050035535.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050040835.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050038679.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8854214	"RAB geranylgeranylation";"TBC/RABGAPs"
XP_050042704.1	13	MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5	"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism"
XP_050049453.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050049093.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050029058.1	10	MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_050025687.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050032267.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition"
XP_050045173.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050023285.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050036662.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050043116.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050033344.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050026321.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050049278.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050029160.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050048414.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050023646.1	9	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Activation of the pre-replicative complex"
XP_050040049.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
XP_050048126.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_050032586.1	9	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050050923.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050029698.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050029370.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050041707.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050024176.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-445355	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"MAP2K and MAPK activation";"Smooth Muscle Contraction"
XP_050046174.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050042316.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050030799.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050030101.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050052174.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050052351.1	8	MetaCyc: PWY-5154;Reactome: R-HSA-70635;MetaCyc: PWY-5;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-4983;KEGG: 00250+6.3.4.5;MetaCyc: PWY-7400	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Canavanine biosynthesis";"Arginine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)"
XP_050038787.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050041428.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050044392.1	6	Reactome: R-HSA-193368;Reactome: R-HSA-2046106;Reactome: R-HSA-390247;Reactome: R-HSA-9033500;Reactome: R-HSA-389887;Reactome: R-HSA-9033241	"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of very long chain fatty acids";"TYSND1 cleaves peroxisomal proteins";"Beta-oxidation of pristanoyl-CoA";"Peroxisomal protein import"
XP_050041885.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050051697.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050049767.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050039431.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050027421.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-416476;Reactome: R-HSA-420499	"Neurexins and neuroligins";"G alpha (q) signalling events";"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050049075.1	13	MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)"
XP_050034817.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050038316.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050038865.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-159227	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA"
XP_050044416.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050044711.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050049405.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_050041504.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050048382.1	9	Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Neurexins and neuroligins"
XP_050030280.1	17	Reactome: R-HSA-167287;KEGG: 04658+3.1.3.16;Reactome: R-HSA-674695;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-113418;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167243	"HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation";"RNA Polymerase II Pre-transcription Events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"T cell receptor signaling pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_050044537.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism"
XP_050022770.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050051694.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050046711.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050023456.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7858;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7340	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_050038352.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050045117.1	10	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Galactose metabolism";"Other glycan degradation"
XP_050052052.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_050040627.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050048145.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050042269.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050039040.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050045474.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050034282.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050030695.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050049102.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050050057.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_050044826.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050023504.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050028195.1	13	Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822	"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)"
XP_050044089.1	5	Reactome: R-HSA-8964616;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-446388	"G beta:gamma signalling through CDC42";"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"
XP_050050529.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050035255.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050037469.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050048976.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050032813.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050038147.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1"
XP_050037165.1	18	MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37	"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Methane metabolism"
XP_050049766.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050050945.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_050049380.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050029026.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050045545.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050051803.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050032863.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050027563.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050027094.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050052031.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050045972.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_050046048.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050051298.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829	"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050039872.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050023648.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-8957275	"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation"
XP_050025278.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050050528.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050050266.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_050050763.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050052616.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050038863.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054	"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA"
XP_050030645.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050039555.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050049111.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050029852.1	29	Reactome: R-HSA-69166;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-5696395;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-3371453;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-6783310	"Removal of the Flap Intermediate";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of Incision Complex in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"Regulation of HSF1-mediated heat shock response";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Fanconi Anemia Pathway"
XP_050025220.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_050037072.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050025434.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050039396.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050048457.1	17	MetaCyc: PWY-6679;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;Reactome: R-HSA-196780;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Jadomycin biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
XP_050040302.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050047293.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050026967.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_050022603.1	16	Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-201722;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519	"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression"
XP_050051006.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050025917.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050032636.1	14	KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-1622;MetaCyc: PWY-181	"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Folate transformations I";"Cyanoamino acid metabolism";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Metabolism of folate and pterines";"One carbon pool by folate";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I";"Formaldehyde assimilation I (serine pathway)";"Photorespiration "
XP_050030300.1	5	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-75896	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis"
XP_050032517.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050035327.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050023529.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050051211.1	4	Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050037178.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_050044530.1	10	Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354	"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy"
XP_050034746.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050047214.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050023375.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050046350.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050038732.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_050039865.1	9	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-446353;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-446343;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Cell-extracellular matrix interactions";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050039343.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050037102.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050029342.1	29	Reactome: R-HSA-3108214;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-3371453;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Regulation of HSF1-mediated heat shock response";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of Incision Complex in GG-NER"
XP_050042479.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050037419.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050049035.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_050030075.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050032704.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050039258.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050028547.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_050025026.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050048885.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_050039342.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050034723.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_050034952.1	8	KEGG: 04660+3.1.3.16;MetaCyc: PWY-5269;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-7817;KEGG: 00564+3.1.3.27	"T cell receptor signaling pathway";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Synthesis of PG";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_050051703.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050024747.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050046119.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation"
XP_050047657.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_050033563.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050025611.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050023886.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050039203.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050025556.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050046989.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050045457.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Ion channel transport"
XP_050033235.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050049459.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050050792.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050040440.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050037071.1	6	KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-6737	"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation III";"Sucrose biosynthesis II";"Starch degradation V"
XP_050051734.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-264870	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_050027281.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050028197.1	4	MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14	"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism"
XP_050031386.1	18	MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Purine metabolism"
XP_050050077.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050026495.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_050037015.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050024209.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050039467.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_050049563.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-1433559	"Neddylation";"Regulation of KIT signaling"
XP_050044254.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050039125.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050034186.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050034302.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050039547.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050046120.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050028602.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050046973.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_050027718.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050029266.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050040372.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050025231.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050038926.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050052574.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050049382.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050023500.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_050051844.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050027699.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_050042155.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050047755.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050031490.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-191859	"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"snRNP Assembly"
XP_050050265.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_050046149.1	17	Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-69205;Reactome: R-HSA-111448;Reactome: R-HSA-2173796;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-1538133;Reactome: R-HSA-113501	"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"G1/S-Specific Transcription";"Activation of NOXA and translocation to mitochondria";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_050048207.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050027484.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050034321.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050049311.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050050641.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050051161.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_050045039.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_050023418.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation"
XP_050051971.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050035530.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050034236.1	12	MetaCyc: PWY-6728;KEGG: 00640+5.1.99.1;KEGG: 00720+5.1.99.1;Reactome: R-HSA-71032;KEGG: 00280+5.1.99.1;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5741;MetaCyc: PWY-8086;MetaCyc: PWY-7854;MetaCyc: PWY-7384;KEGG: 00630+5.1.99.1	"Methylaspartate cycle";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Propionyl-CoA catabolism";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Ethylmalonyl-coa pathway";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Glyoxylate and dicarboxylate metabolism"
XP_050050855.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050035919.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050045386.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050035464.1	4	MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism"
XP_050048407.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050045628.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050051290.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050048971.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_050036224.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050049270.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050035408.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_050050507.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050049771.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050029297.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050034318.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050039285.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_050039241.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050037069.1	6	MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-5941	"Starch degradation III";"Sucrose biosynthesis II";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II"
XP_050029432.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050028600.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050027792.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050033363.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050048471.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050038681.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050025367.1	4	KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050049353.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-381038	"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes"
XP_050045259.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_050025949.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050040993.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050049612.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050029880.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_050034794.1	8	MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7187;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_050029437.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050026257.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_050042082.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114	"Circadian Clock";"Estrogen-dependent gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_050037405.1	2	Reactome: R-HSA-5619055;Reactome: R-HSA-425561	"Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI)";"Sodium/Calcium exchangers"
XP_050039386.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050034724.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_050044695.1	15	Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586	"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence"
XP_050045772.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_050051288.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050030251.1	5	Reactome: R-HSA-9627069;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"Formation of apoptosome"
XP_050031957.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-909733	"Interferon gamma signaling";"Interferon alpha/beta signaling"
XP_050045037.1	6	Reactome: R-HSA-5609978;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370	"Defective GALT can cause Galactosemia";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism"
XP_050048127.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_050041682.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050024952.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050039304.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050043899.1	11	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_050028163.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050048461.1	17	KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;Reactome: R-HSA-200425;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2	"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism"
XP_050030802.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050045508.1	3	Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import"
XP_050037458.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-8053;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4	"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Synthesis of PC";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_050027462.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050050949.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_050029327.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050038509.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050030820.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050023671.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050049552.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_050033847.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050032347.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050050553.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425	"Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_050024091.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050041928.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
YP_010283878.1	7	MetaCyc: PWY-5083;MetaCyc: PWY-3781;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.2;Reactome: R-HSA-611105;MetaCyc: PWY-4302;Reactome: R-HSA-6799198	"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis"
XP_050039031.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050050230.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050047995.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-9648025	"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation"
XP_050026762.1	14	MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;Reactome: R-HSA-499943;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Interconversion of nucleotide di- and triphosphates";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism"
XP_050033771.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050032513.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Ub-specific processing proteases"
XP_050050697.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952	"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions"
XP_050034729.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_050025426.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050036428.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_050026278.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050049259.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050022864.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050024745.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050032721.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050035479.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050031675.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050052226.1	15	Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation"
XP_050034681.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050030944.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050045971.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_050037558.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050033920.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_050037528.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050044388.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050023616.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050041972.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050023730.1	32	Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242	"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_050049777.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050042818.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050023568.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050031477.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050041958.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050044026.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-5682294	"ABC transporters in lipid homeostasis";"Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B"
XP_050029447.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050023313.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050044807.1	17	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5685938	"Human cytomegalovirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"Thermogenesis";"Fanconi Anemia Pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"HDR through Single Strand Annealing (SSA)"
XP_050024929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050052550.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050044364.1	11	MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7586;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-7456;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-3861	"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Mannitol biosynthesis";"Mannitol degradation II"
XP_050023480.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050049501.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542	"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation"
XP_050030937.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174154	"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin"
XP_050034049.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_050046034.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050047778.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-176409	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_050045558.1	7	Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)"
XP_050045409.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050047365.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050027674.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050047055.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050034901.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050032638.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050051593.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_050049747.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050030512.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050034244.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_050032018.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050035323.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050047529.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050041548.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050036805.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_050030314.1	3	MetaCyc: PWY-7369;KEGG: 00730+3.6.1.28;Reactome: R-HSA-196819	"Thiamine triphosphate metabolism";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_050023789.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_050049439.1	2	Reactome: R-HSA-210745;Reactome: R-HSA-210747	"Regulation of gene expression in beta cells";"Regulation of gene expression in early pancreatic precursor cells"
XP_050049481.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050022584.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050024865.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050044713.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_050030815.1	4	Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;Reactome: R-HSA-4719360	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_050052679.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050023380.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050035507.1	3	Reactome: R-HSA-948021;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_050030635.1	4	KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_050049557.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050023570.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050045141.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050050754.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_050049218.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
YP_010283881.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050033366.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_050031048.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050038845.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_050040006.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050041315.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050026074.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050038357.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050032825.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;Reactome: R-HSA-1474151;MetaCyc: PWY-6614;MetaCyc: PWY-3841	"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Folate biosynthesis";"One carbon pool by folate";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)"
XP_050028603.1	16	Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-190873;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-164939;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"Gap junction degradation";"LDL clearance";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis"
XP_050041909.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050041863.1	11	KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-7254;MetaCyc: PWY-7268;MetaCyc: PWY-6549;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42	"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_050040236.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_050041903.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050047048.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050036132.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050043309.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050026353.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5	"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism"
XP_050042454.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-432142	"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Chylomicron remodeling";"Chylomicron assembly";"Scavenging by Class H Receptors";"VLDL clearance";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"VLDL assembly";"Platelet sensitization by LDL"
XP_050028096.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050045190.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050039364.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050025610.1	2	KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050036227.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050034918.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050042030.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050027440.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050048063.1	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
XP_050041182.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_050043307.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050032729.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050049306.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050034468.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050047998.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716	"EML4 and NUDC in mitotic spindle formation";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"RAF activation";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_050048147.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050039335.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;MetaCyc: PWY-7782;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-7886;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Choline biosynthesis I";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC"
XP_050040994.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050022595.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050051336.1	12	Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery"
XP_050032650.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050040727.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676	"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle"
XP_050050347.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_050029936.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440	"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_050036234.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050047866.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_050044403.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_050033904.1	12	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)"
XP_050039510.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665	"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_050023316.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050023824.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
XP_050034063.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050041704.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050041998.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183	"Activation of the pre-replicative complex";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand"
XP_050032656.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050051245.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050039236.1	15	Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408	"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation"
XP_050050681.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9617324	"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_050045195.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050030520.1	4	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;Reactome: R-HSA-196843;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Thiamine metabolism"
XP_050049264.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050042899.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050052241.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400	"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_050029927.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050039425.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050036394.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050024741.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050051435.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050025352.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_050029646.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_050038124.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050039361.1	9	KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883	"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II"
XP_050025838.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050046150.1	17	Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-2559580;Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-1912408;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-113501;Reactome: R-HSA-111448;Reactome: R-HSA-2173796;Reactome: R-HSA-8953750;Reactome: R-HSA-139915;Reactome: R-HSA-9616222;Reactome: R-HSA-2559585	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Oxidative Stress Induced Senescence";"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Pre-NOTCH Transcription and Translation";"G1/S-Specific Transcription";"G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of NOXA and translocation to mitochondria";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional Regulation by E2F6";"Activation of PUMA and translocation to mitochondria";"Transcriptional regulation of granulopoiesis";"Oncogene Induced Senescence"
XP_050031152.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050035529.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050036596.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050043710.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050050829.1	3	KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217	"Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage"
XP_050029918.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-983231	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production"
XP_050037925.1	17	MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690	"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Pyruvate metabolism";"TCA cycle II (plants and fungi)"
XP_050033343.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050023744.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_050031198.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050048349.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050040417.1	8	MetaCyc: PWY-7733;MetaCyc: PWY-7717;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-6309;MetaCyc: PWY-5651;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7765	"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
XP_050037480.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_050038968.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-170822	"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_050034904.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050044385.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050039546.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050029837.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050044714.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_050046816.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050042925.1	5	KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;Reactome: R-HSA-5579006	"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_050050723.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050048921.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_050049325.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_050023727.1	32	Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167246	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript"
XP_050038650.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_050049907.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050049339.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050042702.1	13	MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)"
XP_050044127.1	5	Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_050039776.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050042319.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050029341.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050050019.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050049358.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050041845.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050027684.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050035170.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_050048387.1	2	Reactome: R-HSA-69231;Reactome: R-HSA-8934593	"Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity"
XP_050040329.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050026695.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050050527.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050042107.1	24	Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-392517;Reactome: R-HSA-163560;Reactome: R-HSA-432040;Reactome: R-HSA-5610785;Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-9634600;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-9010642;Reactome: R-HSA-111931;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-422356;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-8963896;Reactome: R-HSA-8853659;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5621575;KEGG: 04150+2.7.11.11	"PKA activation";"PKA activation in glucagon signalling";"Rap1 signalling";"Triglyceride catabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"GLI3 is processed to GLI3R by the proteasome";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"ROBO receptors bind AKAP5";"PKA-mediated phosphorylation of CREB";"DARPP-32 events";"Hedgehog 'off' state";"Regulation of insulin secretion";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"HDL assembly";"RET signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"CD209 (DC-SIGN) signaling";"mTOR signaling pathway"
XP_050026414.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-73776	"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape"
XP_050052567.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050032081.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050040289.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050025728.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050039338.1	7	MetaCyc: PWY-7886;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Synthesis of PC";"Choline biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_050050688.1	19	Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"RAF/MAP kinase cascade"
XP_050050843.1	11	Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-72163;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408	"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"mRNA Splicing - Major Pathway";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation"
XP_050052635.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050023725.1	32	Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167238	"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050024513.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050047517.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050031929.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050039699.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598	"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis"
XP_050042788.1	56	Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176	"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_050027650.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050051570.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050037313.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination"
XP_050044983.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050024744.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050031476.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050027326.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050047606.1	44	Reactome: R-HSA-982772;Reactome: R-HSA-5674135;Reactome: R-HSA-2559585;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-5673001;Reactome: R-HSA-444257;Reactome: R-HSA-6802952;Reactome: R-HSA-198753;Reactome: R-HSA-5654727;Reactome: R-HSA-5654732;Reactome: R-HSA-6802946;Reactome: R-HSA-881907;Reactome: R-HSA-170968;Reactome: R-HSA-5654733;Reactome: R-HSA-6802948;Reactome: R-HSA-1295596;Reactome: R-HSA-8943724;Reactome: R-HSA-9634638;Reactome: R-HSA-6802955;Reactome: R-HSA-3371453;Reactome: R-HSA-8939211;Reactome: R-HSA-162658;Reactome: R-HSA-5663213;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-112409;Reactome: R-HSA-5668599;Reactome: R-HSA-74749;Reactome: R-HSA-2559582;Reactome: R-HSA-8940973;Reactome: R-HSA-879415;Reactome: R-HSA-456926;Reactome: R-HSA-6811558;Reactome: R-HSA-5654726;Reactome: R-HSA-202670;Reactome: R-HSA-445144;Reactome: R-HSA-2029482;Reactome: R-HSA-9635465;Reactome: R-HSA-2559580;Reactome: R-HSA-375165;Reactome: R-HSA-9627069;Reactome: R-HSA-5674499	"Growth hormone receptor signaling";"MAP2K and MAPK activation";"Oncogene Induced Senescence";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"RAF/MAP kinase cascade";"RSK activation";"Signaling by BRAF and RAF fusions";"ERK/MAPK targets";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR3 signaling";"Signaling by moderate kinase activity BRAF mutants";"Gastrin-CREB signalling pathway via PKC and MAPK";"Frs2-mediated activation";"Negative regulation of FGFR4 signaling";"Signaling by high-kinase activity BRAF mutants";"Spry regulation of FGF signaling";"Regulation of PTEN gene transcription";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of HSF1-mediated heat shock response";"ESR-mediated signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"RHO GTPases Activate WASPs and WAVEs";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"RAF-independent MAPK1/3 activation";"RHO GTPases Activate NADPH Oxidases";"Signal attenuation";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX2 regulates osteoblast differentiation";"Advanced glycosylation endproduct receptor signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR1 signaling";"ERKs are inactivated";"Signal transduction by L1";"Regulation of actin dynamics for phagocytic cup formation";"Suppression of apoptosis";"Oxidative Stress Induced Senescence";"NCAM signaling for neurite out-growth";"Regulation of the apoptosome activity";"Negative feedback regulation of MAPK pathway"
XP_050026749.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050044955.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050051711.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_050044944.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050038148.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1"
XP_050049329.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050045564.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050041343.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050037314.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_050052569.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050039711.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_050041241.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050025345.1	2	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
XP_050031156.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_050050752.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"mTOR signalling";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_050044702.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050045705.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050027767.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050050101.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050027474.1	7	Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1	"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_050043980.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050034845.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_050046755.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050050751.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_050043175.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050036570.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050031599.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050036417.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050034967.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050040457.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050042259.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050047191.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050036726.1	7	KEGG: 00220+3.5.3.1;MetaCyc: PWY-6922;Reactome: R-HSA-70635;MetaCyc: PWY-31;MetaCyc: PWY-46;MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1	"Arginine biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Canavanine degradation";"Putrescine biosynthesis III";"Urea cycle";"Arginine and proline metabolism"
XP_050044699.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_050037623.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050032712.1	4	Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050028337.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050048018.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050037621.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050040190.1	6	KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22	"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism"
XP_050050144.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050030630.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_050032078.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050044348.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050032783.1	4	MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26	"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate"
XP_050032662.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050026675.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050046063.1	32	Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167162	"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape"
XP_050024666.1	3	Reactome: R-HSA-1300642;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556	"Sperm Motility And Taxes";"Neutrophil degranulation";"ROS and RNS production in phagocytes"
XP_050030818.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050052730.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_050034731.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_050035952.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050022883.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050025848.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity"
XP_050040875.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050034683.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_050047123.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050052189.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050042029.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-70370	"Galactose metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism"
XP_050051924.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_050049882.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050034772.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-8948751	"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity"
XP_050051838.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050049238.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050047769.1	10	Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091	"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells"
XP_050039189.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050036814.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050049362.1	4	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_050030811.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex"
XP_050052711.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_050049804.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050048293.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050027584.1	5	KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892	"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
XP_050041043.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050029938.1	2	KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6	"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism"
XP_050027798.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050025412.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050024030.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050032614.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_050030757.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413	"DNA methylation";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression"
XP_050041884.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050051304.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050041512.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050037063.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050047068.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050041902.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050049471.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_050046883.1	2	MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60	"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis"
XP_050034253.1	15	MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-6886	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycolysis";"Entner-Doudoroff pathway I";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)"
XP_050032322.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050052202.1	4	Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-156581	"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"Methylation"
XP_050029890.1	8	Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841	"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines"
XP_050046933.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation"
XP_050050560.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050051580.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_050023809.1	19	Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8964038	"Chylomicron remodeling";"Scavenging by Class F Receptors";"VLDL clearance";"Chylomicron assembly";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"VLDL assembly";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance"
XP_050040051.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
XP_050027378.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050046829.1	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
XP_050050469.1	7	KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148	"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of PG"
XP_050038581.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050033431.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_050046188.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050049232.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_050044200.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050051763.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_050029776.1	5	KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6	"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Purine metabolism"
XP_050035993.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050039456.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050026205.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis"
XP_050031227.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050050174.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050025144.1	20	Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942	"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)"
XP_050037420.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050028975.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_050033146.1	37	Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-9639288;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-983170;Reactome: R-HSA-159227;Reactome: R-HSA-204005;Reactome: R-HSA-191859;Reactome: R-HSA-68877	"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amino acids regulate mTORC1";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Transport of the SLBP independent Mature mRNA";"COPII-mediated vesicle transport";"snRNP Assembly";"Mitotic Prometaphase"
XP_050023321.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
XP_050042202.1	4	KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_050036466.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050050782.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050049673.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050045300.1	33	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-69273;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-69231;Reactome: R-HSA-6781827;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin D associated events in G1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050032648.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050040138.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_050041736.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050027933.1	4	KEGG: 00633+2.3.1.5;KEGG: 00232+2.3.1.5;KEGG: 00983+2.3.1.5;Reactome: R-HSA-156582	"Nitrotoluene degradation";"Caffeine metabolism";"Drug metabolism - other enzymes";"Acetylation"
XP_050050304.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050025609.1	2	KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050036142.1	8	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1"
XP_050044691.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050042045.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050036569.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050023604.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050043511.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050045481.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050035998.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050025777.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050023867.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050050655.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050036113.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050050224.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050049068.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050045940.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050040711.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_050044281.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050037137.1	30	Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-2564830;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-113418	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex"
XP_050050103.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050041931.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050040277.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050039345.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050026984.1	13	MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883	"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II"
XP_050039519.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050040332.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050039305.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050042268.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050028876.1	9	MetaCyc: PWY-381;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2	"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_050035850.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050025446.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-241	"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_050034277.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050049137.1	9	MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822	"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)"
XP_050044825.1	5	Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;MetaCyc: PWY-922	"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I"
XP_050025490.1	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050026737.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050029903.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050026084.1	4	MetaCyc: PWY-5651;MetaCyc: PWY-6309;KEGG: 00380+3.7.1.3;Reactome: R-HSA-71240	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Tryptophan catabolism"
XP_050027411.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050043296.1	19	MetaCyc: PWY-6545;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7187;Reactome: R-HSA-380270;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7221	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis"
XP_050044386.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050030952.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050052821.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050038645.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050050199.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050026336.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050039399.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050025373.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050023610.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050048619.1	30	KEGG: 05163+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-199418;Reactome: R-HSA-8948751;Reactome: R-HSA-8941332;Reactome: R-HSA-5674400;Reactome: R-HSA-6804758;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-8876198;Reactome: R-HSA-198323;Reactome: R-HSA-211163;Reactome: R-HSA-6804759;Reactome: R-HSA-9614399;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-9634638;Reactome: R-HSA-1358803;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69656;KEGG: 04926+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;Reactome: R-HSA-69202	"Human cytomegalovirus infection";"CTLA4 inhibitory signaling";"Negative regulation of the PI3K/AKT network";"Regulation of PTEN stability and activity";"RUNX2 regulates genes involved in cell migration";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Activity through Acetylation";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the nucleus";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RAB GEFs exchange GTP for GDP on RABs";"AKT phosphorylates targets in the cytosol";"AKT-mediated inactivation of FOXO1A";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of localization of FOXO transcription factors";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of ERBB2:ERBB3 signaling";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Relaxin signaling pathway";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"Cyclin E associated events during G1/S transition"
XP_050025092.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050028992.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_050026957.1	7	Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"HCMV Early Events";"Regulation of PTEN gene transcription"
XP_050037583.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050025301.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050028748.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050035110.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"PKMTs methylate histone lysines"
XP_050027574.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050027404.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050027048.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050044812.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_050038994.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050050319.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_050032836.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050029953.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050050552.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_050042301.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050035813.1	3	Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144	"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_050027769.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050042296.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050043064.1	13	Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822	"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)"
XP_050030182.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050041282.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_050050659.1	2	Reactome: R-HSA-5620912;Reactome: R-HSA-5610787	"Anchoring of the basal body to the plasma membrane";"Hedgehog 'off' state"
XP_050029850.1	17	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_050044236.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_050050756.1	9	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_050043304.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050047674.1	2	Reactome: R-HSA-69231;Reactome: R-HSA-8934593	"Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity"
XP_050032353.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050050233.1	5	MetaCyc: PWY-7919;Reactome: R-HSA-532668;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_050029771.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050028325.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_050023175.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050035974.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050040873.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050042463.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_050029819.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050032997.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
XP_050029441.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050051397.1	20	Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Polymerase switching";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
XP_050040023.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050033554.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050024015.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_050026976.1	8	Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_050045148.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050034973.1	7	Reactome: R-HSA-446193;KEGG: 00510+2.7.8.15;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;MetaCyc: PWY-5265;MetaCyc: PWY-6471;Reactome: R-HSA-4549356	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2"
XP_050043821.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_050039106.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
XP_050036549.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050023187.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050048527.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050030771.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050029321.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_050035094.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050049008.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050036263.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050038834.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_050035496.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050031377.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050051865.1	16	Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196	"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling"
XP_050030123.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_050023299.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050035979.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050025400.1	18	KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4	"Ether lipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Arachidonic acid metabolism";"Glycerophospholipid metabolism"
XP_050023721.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling"
XP_050025001.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050032424.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050026808.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050030786.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050044710.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050036861.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050039551.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050046068.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_050039084.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050025909.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050035483.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050049296.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_050043849.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_050047139.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052	"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion"
XP_050025193.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050029647.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050052157.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5469	"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis"
XP_050042709.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050052018.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050028166.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050023782.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050026206.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis"
XP_050033625.1	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
XP_050044543.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_050044608.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050029436.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050045014.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050051316.1	9	Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-5218920	"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"VEGFR2 mediated vascular permeability"
XP_050030759.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050029872.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050033827.1	7	Reactome: R-HSA-77111;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;Reactome: R-HSA-9033241;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4	"Synthesis of Ketone Bodies";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Peroxisomal protein import";"Mevalonate degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies"
XP_050051481.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050030715.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050043741.1	10	MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061	"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I"
XP_050040959.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-879415	"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling"
XP_050048001.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050039959.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050043181.1	25	Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport"
XP_050052207.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050051866.1	16	Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1251985;Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604	"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Nuclear signaling by ERBB4";"ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling"
XP_050035315.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050027118.1	57	Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870	"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins"
XP_050048132.1	7	Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050024819.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050034928.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050031446.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606	"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_050034835.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050027386.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050028296.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_050033232.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050052546.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050032008.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050032828.1	6	KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403	"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)"
XP_050032927.1	8	KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050042138.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050034315.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050039395.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050031905.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050043528.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050030156.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050044957.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_050047137.1	7	Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion"
XP_050036825.1	4	MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27	"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism"
XP_050030698.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050023776.1	18	Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-113418	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex"
XP_050043228.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_050050426.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2"
XP_050049216.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050044199.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_050033257.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050038686.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050035976.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase"
XP_050031698.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_050023603.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050029919.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-381676	"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"PKA activation";"DARPP-32 events";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_050046725.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050035763.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050037224.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050027410.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050049138.1	9	MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II"
XP_050042176.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_050023637.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050050241.1	6	MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_050046646.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050052159.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461	"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation"
XP_050032815.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050035489.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050039080.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050023018.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050029156.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050052141.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050052056.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_050026073.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_050042150.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_050031481.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050028756.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050042728.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050050692.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952	"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions"
XP_050049217.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050046075.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050028834.1	3	KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741	"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050034475.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670	"Glycosphingolipid metabolism";"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis"
XP_050049323.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_050036033.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050048426.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050039773.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050048468.1	17	KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2	"Fatty acid biosynthesis";"Biotin transport and metabolism";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism"
XP_050052557.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050046080.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050040551.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519	"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression"
XP_050035422.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050025614.1	3	KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_050030651.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050033726.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050040553.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_050042130.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050024361.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_050047329.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050045389.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050047937.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050037098.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex"
XP_050030610.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_050044823.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050031817.1	4	KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_050038847.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_050052023.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050025491.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism"
XP_050034533.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050025577.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050023361.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050045633.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-9627069	"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity"
XP_050036030.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050043326.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050039768.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050048805.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050051868.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-1251985;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Nuclear signaling by ERBB4";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling"
XP_050040038.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050041412.1	13	Reactome: R-HSA-389357;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-3371571	"CD28 dependent PI3K/Akt signaling";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation"
XP_050027417.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050026493.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
YP_010283875.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050037068.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050030924.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050044598.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050024724.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050052825.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050043327.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050027508.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050026318.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050052553.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050047962.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050035462.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_050022630.1	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
XP_050030178.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050042413.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050026983.1	13	MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2022857	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Keratan sulfate degradation"
XP_050045548.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050027173.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050048803.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_050051356.1	26	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly"
XP_050032269.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050052639.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050044362.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050052835.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050023598.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050027734.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_050049787.1	8	Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-167590	"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation"
XP_050032357.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667	"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I"
XP_050030649.1	4	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"MET activates PTK2 signaling"
XP_050036821.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_050022813.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050036347.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050029699.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050032840.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050037167.1	17	MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561	"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_050032708.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050023273.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050052234.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_050030138.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
XP_050043903.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050031247.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050033964.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins"
XP_050025480.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050026792.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050049592.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_050046343.1	6	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)"
XP_050031904.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050024255.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050037204.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050048381.1	9	Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662	"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling"
XP_050048205.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050023476.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464	"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins"
XP_050025112.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_050052030.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050043506.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050034198.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050030241.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_050046958.1	3	Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859	"Protein methylation";"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050043472.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_050052763.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398	"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway"
XP_050032701.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050027526.1	7	KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202	"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_050043348.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050044814.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_050026756.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_050041922.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050040886.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_050032670.1	17	Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Processive synthesis on the lagging strand";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_050032679.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050049896.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050048637.1	13	MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-2161;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841	"L-histidine degradation III";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)"
XP_050029958.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050027634.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050043803.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050038099.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_050024782.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_050030175.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050025634.1	4	KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050045234.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050044094.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_050033752.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria"
XP_050032373.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_050036546.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050029839.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050040366.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050030053.1	5	Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
XP_050023324.1	3	Reactome: R-HSA-3359473;Reactome: R-HSA-196741;Reactome: R-HSA-3359474	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC"
XP_050047208.1	6	Reactome: R-HSA-163210;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Mitochondrial protein import";"Cristae formation"
XP_050046831.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050031347.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050025560.1	12	KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13	"Methane metabolism";"Glycolysis";"Gluconeogenesis";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism"
XP_050025357.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050036380.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050044946.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050049337.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050032453.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050031221.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050045648.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_050052798.1	4	Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism"
XP_050039987.1	7	MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_050024323.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050047857.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050043321.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050042240.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-202733	"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Scavenging by Class H Receptors";"Chylomicron assembly";"Scavenging by Class F Receptors";"VLDL clearance";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Chylomicron remodeling";"VLDL assembly";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall"
XP_050049568.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050022610.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050034800.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050038418.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_050032511.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases"
XP_050048047.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050051059.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050050150.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_050040829.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050044747.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050045063.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_050025981.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050049595.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050023608.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049616.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade"
XP_050025702.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050051381.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2467813	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids"
XP_050048427.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_050022943.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050033491.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_050026121.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050022494.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050043325.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050040012.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
YP_010283877.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050047330.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050031106.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050026700.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050027478.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex"
XP_050050223.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050027667.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_050038327.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050041478.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050041314.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050048292.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050048255.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_050038921.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis"
XP_050026079.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050037573.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7	"Betanidin degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis"
XP_050050831.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050048931.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050036167.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_050044798.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050044408.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_050049687.1	7	KEGG: 00230+2.4.2.7;MetaCyc: PWY-6605;Reactome: R-HSA-74217;MetaCyc: PWY-7807;MetaCyc: PWY-6610;MetaCyc: PWY-7805;Reactome: R-HSA-6798695	"Purine metabolism";"Adenine and adenosine salvage II";"Purine salvage";"Glyphosate degradation III";"Adenine salvage";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation"
XP_050029909.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050047730.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050049886.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050040744.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_050023778.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050052655.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050045960.1	6	MetaCyc: PWY-6599;KEGG: 00230+2.4.2.8;MetaCyc: PWY-6610;MetaCyc: PWY-6609;MetaCyc: PWY-6620;KEGG: 00983+2.4.2.8	"Guanine and guanosine salvage II";"Purine metabolism";"Adenine salvage";"Adenine and adenosine salvage III";"Guanine and guanosine salvage";"Drug metabolism - other enzymes"
XP_050033833.1	57	Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-174113	"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1"
XP_050030468.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050023168.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_050027345.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050041873.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050048359.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050043783.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050040736.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050031600.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_050038974.1	9	KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52	"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_050039708.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
XP_050044509.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_050046722.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050023708.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555	"Regulation of signaling by CBL";"Downstream signal transduction";"MET receptor recycling";"MET activates RAP1 and RAC1"
XP_050045171.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050026402.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050030923.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050035166.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050050107.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050026580.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050038719.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050048723.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_050047551.1	15	Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050031478.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050024512.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050031908.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_050030375.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001	"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism"
XP_050048623.1	6	Reactome: R-HSA-71240;MetaCyc: PWY-7765;MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;MetaCyc: PWY-6309	"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_050029960.1	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050045006.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_050052273.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050038809.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_050025209.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050030608.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050043324.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050046753.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050024312.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050039798.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050027935.1	4	Reactome: R-HSA-156582;KEGG: 00232+2.3.1.5;KEGG: 00983+2.3.1.5;KEGG: 00633+2.3.1.5	"Acetylation";"Caffeine metabolism";"Drug metabolism - other enzymes";"Nitrotoluene degradation"
XP_050036032.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050043147.1	40	Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-72165	"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway"
XP_050052053.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
YP_010283873.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050033588.1	11	KEGG: 00220+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;Reactome: R-HSA-210455;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549	"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III"
XP_050049211.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_050038768.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050042966.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050046740.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_050029862.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation"
XP_050022493.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050051715.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation"
XP_050034799.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050052128.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050050901.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050036229.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050047404.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050051813.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050029445.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050034323.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050038675.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050050408.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_050037661.1	12	KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803	"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_050024090.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050033905.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050048545.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050035975.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050049248.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_050039846.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050049374.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050040902.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050032250.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050029459.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050023900.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050032484.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_050044689.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050025067.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050044610.1	4	Reactome: R-HSA-70921;MetaCyc: PWY-5030;KEGG: 00340+3.5.2.7;MetaCyc: PWY-5028	"Histidine catabolism";"L-histidine degradation III";"Histidine metabolism";"L-histidine degradation II"
XP_050032519.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050033083.1	3	Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13	"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system"
XP_050032774.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050052657.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050027475.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050041692.1	10	MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10	"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Butanoate metabolism"
XP_050045482.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050046873.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050032732.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695	"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation"
XP_050035823.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050047118.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681	"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling"
XP_050033594.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050048216.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050045174.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050035448.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_050040027.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_050036225.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050047035.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050050766.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050022527.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050048458.1	17	KEGG: 00061+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;MetaCyc: PWY-6679;Reactome: R-HSA-196780;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381	"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_050027551.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050044294.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050049540.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050022518.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761	"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_050030155.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050039429.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050039234.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_050026486.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050032516.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050037699.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_050022593.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050042303.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050040415.1	8	MetaCyc: PWY-7733;MetaCyc: PWY-7717;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-6309;MetaCyc: PWY-5651;MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9	"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism"
XP_050037417.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-7254;MetaCyc: PWY-8086	"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_050034802.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050046038.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050042681.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_050029923.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050036049.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_050028172.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050026425.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
XP_050041147.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_050035316.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050051836.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050023569.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050030111.1	2	Reactome: R-HSA-74259;KEGG: 00230+3.6.1.66	"Purine catabolism";"Purine metabolism"
XP_050035217.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050028838.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050027689.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050051471.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050027567.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-156711;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Polo-like kinase mediated events";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_050039286.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050036622.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_050035984.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295	"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation"
XP_050042181.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807	"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_050036226.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050030700.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050025138.1	2	Reactome: R-HSA-139853;Reactome: R-HSA-418346	"Elevation of cytosolic Ca2+ levels";"Platelet homeostasis"
XP_050039722.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050048399.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050049309.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050026807.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050028646.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_050037144.1	12	MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism"
XP_050052238.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050029902.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050037281.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_050043001.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050022517.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis"
XP_050029084.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_050041374.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_050025217.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_050023914.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050030213.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050025945.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050045329.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050042141.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050023816.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_050032808.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050042137.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050045424.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050047039.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050030938.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-111465	"Activation of ATR in response to replication stress";"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins"
XP_050040055.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050036844.1	7	KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-389661;Reactome: R-HSA-71064	"Lysine degradation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism"
XP_050042257.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050024457.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050034726.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_050048327.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050039769.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050022551.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050023331.1	3	Reactome: R-HSA-75102;Reactome: R-HSA-77042;Reactome: R-HSA-909733	"C6 deamination of adenosine";"Formation of editosomes by ADAR proteins";"Interferon alpha/beta signaling"
XP_050048542.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050044553.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050039068.1	11	Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-112382	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex"
XP_050022472.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050024358.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_050039387.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050035632.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050036862.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050041925.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050051310.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050044277.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050048960.1	6	Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)"
XP_050026013.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism"
XP_050025622.1	24	Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-202040;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-6814122	"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"G-protein activation";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050032639.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050025800.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050039793.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050024867.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050045689.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_050033581.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050037422.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050047121.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050050601.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex"
XP_050052248.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050024718.1	6	Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_050039709.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036	"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II"
XP_050035119.1	14	Reactome: R-HSA-428890;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5620912;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5663220	"Role of ABL in ROBO-SLIT signaling";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Anchoring of the basal body to the plasma membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins"
XP_050044271.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_050049449.1	4	Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Cristae formation"
XP_050033750.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria"
XP_050040570.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_050027743.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050039526.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050049937.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport"
XP_050035017.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050024465.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050025548.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_050026192.1	4	KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)"
XP_050048112.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_050045754.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_050027593.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050039259.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050028813.1	14	Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes"
XP_050041257.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050034126.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_050045631.1	3	KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050033708.1	7	KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;Reactome: R-HSA-77111;Reactome: R-HSA-9033241;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074	"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Synthesis of Ketone Bodies";"Peroxisomal protein import";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Mevalonate degradation"
XP_050030050.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050030506.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854	"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_050040483.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050030586.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050037169.1	18	KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6728	"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle"
XP_050030252.1	5	Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"Formation of apoptosome";"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050046242.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050046688.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050051311.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050036462.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050043306.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050049099.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050047421.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis"
XP_050033896.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_050036228.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050047126.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050027562.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050045166.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050051191.1	3	Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_050023192.1	13	Reactome: R-HSA-5689877;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-110320;Reactome: R-HSA-6798695;Reactome: R-HSA-8876725;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-8866654;Reactome: R-HSA-3371511;Reactome: R-HSA-5689896	"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Translesion Synthesis by POLH";"Neutrophil degranulation";"Protein methylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"E3 ubiquitin ligases ubiquitinate target proteins";"HSF1 activation";"Ovarian tumor domain proteases"
XP_050034653.1	14	Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-6798695	"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neutrophil degranulation"
XP_050041566.1	13	KEGG: 00230+3.6.1.66;MetaCyc: PWY-7206;MetaCyc: PWY-6545;Reactome: R-HSA-74259;MetaCyc: PWY-7187;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9	"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism"
XP_050047530.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050032811.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050043034.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050041946.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050025922.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_050047291.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050029607.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050044204.1	4	Reactome: R-HSA-4570464;Reactome: R-HSA-72163;Reactome: R-HSA-9610379;Reactome: R-HSA-72203	"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway";"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050050919.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432720	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Lysosome Vesicle Biogenesis"
XP_050038062.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050050900.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050028083.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050048790.1	1	KEGG: 00760+1.4.1.21	"Nicotinate and nicotinamide metabolism"
XP_050037111.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050027366.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050027596.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050041999.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69166	"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate"
XP_050023724.1	32	Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-9018519	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression"
XP_050038682.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050040200.1	58	Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5689901;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541	"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Metalloprotease DUBs";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway"
XP_050040162.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_050040899.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050051505.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050024459.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050049483.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-69205	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription"
XP_050038324.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050051512.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050041796.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050032848.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050044965.1	5	Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050025198.1	13	Reactome: R-HSA-74259;MetaCyc: PWY-6545;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9	"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism"
XP_050052495.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050036610.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050050583.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51	"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism"
XP_050034247.1	17	Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-8951664	"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Neddylation"
XP_050051975.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050040482.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050031026.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050029077.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_050040246.1	13	Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"LDL clearance";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis"
XP_050034361.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_050032573.1	5	Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3	"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes"
XP_050042717.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050027509.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050036560.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050048837.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050038140.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN"
XP_050028217.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis"
XP_050044947.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050024204.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050030346.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050044593.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050052019.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050048424.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_050049835.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050039134.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050041975.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050038844.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050048824.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-8941858	"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity"
XP_050050509.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050044773.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_050039358.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050040641.1	10	MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_050034730.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050027030.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050029104.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050047284.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050039606.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050022550.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_050043467.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050036400.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050038555.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050042714.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_050031619.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050032689.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050049317.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050023777.1	18	Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-77075	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050038950.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050049173.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050043448.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050034727.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050024803.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050041755.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050041948.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050042706.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050032012.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050042483.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050036729.1	7	MetaCyc: PWY-6922;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-46;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31	"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Arginine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"Arginine and proline metabolism";"Canavanine degradation"
XP_050052752.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050033239.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097	"DSCAM interactions";"NOD1/2 Signaling Pathway";"p38MAPK events";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_050039447.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050049241.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050042031.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050041344.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050042821.1	3	Reactome: R-HSA-5678520;Reactome: R-HSA-193368;Reactome: R-HSA-159418	"Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Recycling of bile acids and salts"
XP_050035967.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050038836.1	6	MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077	"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"N-acetyl-D-galactosamine degradation"
XP_050043507.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902	"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity"
XP_050038856.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_050036628.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050044193.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity"
XP_050032588.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050048919.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050024784.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050042438.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807	"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_050026811.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050029873.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050036184.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050024276.1	4	KEGG: 00220+3.5.1.5;KEGG: 00791+3.5.1.5;MetaCyc: PWY-5704;KEGG: 00230+3.5.1.5	"Arginine biosynthesis";"Atrazine degradation";"Urea degradation II";"Purine metabolism"
XP_050023729.1	32	Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription of the HIV genome"
XP_050035136.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050026697.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050040909.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050044858.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050049057.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_050027790.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050023609.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050024941.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050050762.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050035620.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050026969.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_050022605.1	16	Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-201722;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
XP_050023614.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050042597.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050050324.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-877300	"Interferon alpha/beta signaling";"Interferon gamma signaling"
XP_050039366.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_050048140.1	13	MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;Reactome: R-HSA-9027277;MetaCyc: PWY-6367;Reactome: R-HSA-2029485;Reactome: R-HSA-2424491;MetaCyc: PWY-6351;Reactome: R-HSA-202433;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796;KEGG: 04070+3.1.4.11	"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol-5-phosphate metabolism";"Role of phospholipids in phagocytosis";"DAP12 signaling";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules";"Inositol phosphate metabolism";"FCERI mediated MAPK activation";"Phosphatidylinositol signaling system"
XP_050026722.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050024885.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050029842.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_050027669.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_050034858.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis"
XP_050023814.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_050026503.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050041862.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050050873.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050051422.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050029516.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-191859	"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly"
XP_050023186.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050044799.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050026513.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_050025948.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050027420.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050024686.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050043913.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050026338.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050052813.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050033753.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_050029054.1	10	MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis"
XP_050031259.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050047311.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050052130.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050047285.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050031258.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050051318.1	9	Reactome: R-HSA-2871809;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796	"FCERI mediated Ca+2 mobilization";"Rho GTPase cycle";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation"
XP_050051577.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_050046841.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050050488.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_050034768.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050039587.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050048155.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050046832.1	6	MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism"
XP_050044338.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050022985.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050045062.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050051894.1	16	MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-7124;Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-6142	"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Glycolysis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050033967.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050025202.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050023583.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050037081.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050025615.1	13	KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52	"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_050046512.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050026521.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050040046.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050030472.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_050049599.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_050026021.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050036813.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050050513.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050029505.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-110381;Reactome: R-HSA-5649702	"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050025232.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050047698.1	9	MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061	"Glutathione-mediated detoxification II";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification I"
XP_050027585.1	5	MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7	"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism"
XP_050051460.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165181	"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Inhibition of TSC complex formation by PKB"
XP_050032784.1	4	MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050032610.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050038769.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050043317.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050036145.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_050036157.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050041281.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_050047407.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050046981.1	5	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation"
XP_050030604.1	13	MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5132;MetaCyc: PWY-5133;KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00010+6.2.1.1	"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Ethanol oxidation";"Glycolysis / Gluconeogenesis"
XP_050045238.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050039895.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050050515.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050048936.1	5	Reactome: R-HSA-392154;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis"
XP_050035407.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-416476	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events"
XP_050043649.1	12	Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_050044986.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050049526.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050041483.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050047174.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050043184.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049667.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050041424.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050031954.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050041753.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_050039385.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050050748.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050034685.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050039333.1	7	Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7886;MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782;MetaCyc: PWY-3385	"Synthesis of PC";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Choline biosynthesis I"
XP_050031510.1	18	Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7221;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_050026821.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050050837.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050031110.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050043104.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050038969.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159231	"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_050030061.1	5	Reactome: R-HSA-111458;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-9627069	"Formation of apoptosome";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity"
XP_050033968.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex"
XP_050033244.1	5	Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-376172	"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"p38MAPK events";"NOD1/2 Signaling Pathway";"DSCAM interactions"
XP_050027304.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_050048049.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050034609.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050049843.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_050031435.1	5	KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050032945.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050048423.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_050044394.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_050047714.1	9	KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-156590	"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione conjugation"
XP_050047245.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050028082.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050029168.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050039374.1	9	MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-4755583;KEGG: 00230+6.3.4.13;KEGG: 00510+2.7.1.108;Reactome: R-HSA-73817;Reactome: R-HSA-446199;MetaCyc: PWY-6121;MetaCyc: PWY-6129	"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Purine metabolism";"N-Glycan biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"5-aminoimidazole ribonucleotide biosynthesis I";"Dolichol and dolichyl phosphate biosynthesis"
XP_050031826.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050030830.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050049438.1	8	MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;KEGG: 00030+5.3.1.6;Reactome: R-HSA-71336;Reactome: R-HSA-5659996;MetaCyc: PWY-1861;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6	"Rubisco shunt";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms"
XP_050052751.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050026081.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_050034469.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050052114.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050036547.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050044337.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050044081.1	5	Reactome: R-HSA-1679131;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Trafficking and processing of endosomal TLR";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_050047037.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050038927.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050032270.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050034720.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050023173.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050049932.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050032263.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5466	"Justicidin B biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis"
XP_050043109.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050035981.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050050999.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_050043541.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050026685.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_050042039.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050031203.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050049844.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_050031202.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050032520.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050029841.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050026849.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050031820.1	4	MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_050030160.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050031831.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050043724.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050037849.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050024307.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050052373.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050046054.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050042344.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050044801.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050051244.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050033197.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_050031579.1	6	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980	"Cristae formation";"Mitochondrial protein import";"Oxidative phosphorylation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis"
XP_050046300.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050029334.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050034902.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050043548.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions"
XP_050045685.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050028145.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050049688.1	2	KEGG: 00240+3.6.1.12;Reactome: R-HSA-499943	"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050047157.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_050049624.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050034680.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050045008.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050033633.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050043493.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_050033346.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050052196.1	1	Reactome: R-HSA-9610379	"HCMV Late Events"
XP_050038179.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050023189.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050022977.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_050041013.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050026776.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050042391.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885	"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins"
XP_050029336.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408	"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation"
XP_050039214.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050051812.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050045480.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050037529.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050037277.1	8	MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_050030653.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453	"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response"
XP_050042766.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050052579.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050040708.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050052555.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050052661.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027202.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050044084.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050045158.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050024953.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050049842.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_050024595.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050034778.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050026960.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472	"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"HCMV Early Events";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050039330.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174154	"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin"
XP_050025213.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050023319.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050051602.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050024010.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_050036338.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050024326.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050027566.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-156711;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Polo-like kinase mediated events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_050033884.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050022842.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050044834.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050047732.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050028218.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813	"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Separation of Sister Chromatids"
XP_050052836.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050027498.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050038770.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050025381.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_050036827.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-191859	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly"
XP_050032598.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050046097.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050045119.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050044013.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050041702.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050034932.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050047994.1	22	Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558	"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Platelet sensitization by LDL";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_050029374.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050039185.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050026869.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-5362798;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050029921.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050043404.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050045053.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050052548.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050036491.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050045146.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050049195.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050050105.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050047215.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050039292.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050045478.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_050049222.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050048953.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_050028048.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050044576.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050038648.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050037145.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4	"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_050039894.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050042901.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050027600.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_050050274.1	4	MetaCyc: PWY-6823;MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050047797.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050043782.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050032154.1	3	Reactome: R-HSA-5578995;KEGG: 00983+2.1.1.67;Reactome: R-HSA-156581	"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Drug metabolism - other enzymes";"Methylation"
XP_050030744.1	6	KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165	"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_050046803.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050051073.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050032017.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050039306.1	8	Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050037037.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_050042989.1	10	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847	"Human cytomegalovirus infection";"Ub-specific processing proteases";"PI3K-Akt signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"HATs acetylate histones"
XP_050045665.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049876.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050039662.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050050158.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_050031206.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050025697.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors"
XP_050026015.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway"
XP_050041971.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050027176.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050031222.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050033709.1	7	MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4	"Mevalonate degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Peroxisomal protein import";"Synthesis of Ketone Bodies";"Geraniol degradation";"Valine, leucine and isoleucine degradation"
XP_050038199.1	42	Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-9616222;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-977225;Reactome: R-HSA-5693565;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-3214847;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-3214815;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-5617472;Reactome: R-HSA-5334118;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-73728;Reactome: R-HSA-5625886	"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"Transcriptional regulation of granulopoiesis";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"Amyloid fiber formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDACs deacetylate histones";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA methylation";"Meiotic recombination";"RMTs methylate histone arginines";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_050031011.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_050032728.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-6798695	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Neutrophil degranulation"
XP_050029802.1	57	Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424	"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling"
XP_050051757.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050038910.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050030782.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050042596.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050039329.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174084	"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_050035321.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050032562.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050051194.1	40	MetaCyc: PWY-6944;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7216;MetaCyc: PWY-7726;MetaCyc: PWY-5109;KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-7779;MetaCyc: PWY-7401;MetaCyc: PWY-7007;MetaCyc: PWY-1361;MetaCyc: PWY-7778;KEGG: 00410+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-5177;MetaCyc: PWY-6883;MetaCyc: PWY-6863;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-7656;MetaCyc: PWY-6946;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17+1.1.1.35	"Androstenedione degradation";"Caprolactam degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Phenylalanine metabolism";"Pyruvate fermentation to butanol I";"Methyl tert-butyl ether degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl ketone biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"2-methylpropene degradation";"beta-Alanine metabolism";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Butanoate metabolism";"Limonene and pinene degradation";"Geraniol degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid salvage";"Lysine degradation";"Fatty acid elongation";"Toluene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Aminobenzoate degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes"
XP_050039554.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_050034478.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050037617.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport"
XP_050023620.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050029444.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050037920.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050024428.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050026624.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050051832.1	6	MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;Reactome: R-HSA-446199;MetaCyc: PWY-7391;Reactome: R-HSA-191273	"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis"
XP_050030764.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050040980.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050022606.1	16	Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"HATs acetylate histones";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
XP_050051360.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050028252.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_050030853.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050027328.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050047777.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050040022.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050052586.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050040015.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes"
XP_050038590.1	14	Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6728	"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle"
XP_050050652.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050050370.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050042154.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050033903.1	12	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685942	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Homologous Recombination (HRR)"
XP_050037775.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II"
XP_050051315.1	9	Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-2871809	"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization"
XP_050029488.1	3	KEGG: 00240+3.5.4.12;Reactome: R-HSA-499943;MetaCyc: PWY-7210	"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_050033336.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050050650.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050048737.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050027591.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050035880.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050028895.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050035083.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050043832.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050040339.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-69017	"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6"
XP_050047166.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050041930.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050052640.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050032564.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050024808.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050043764.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050033519.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050033921.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_050040910.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_050049707.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050051772.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_050045468.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050040900.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050040119.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050026579.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050044042.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_050048388.1	2	Reactome: R-HSA-8934593;Reactome: R-HSA-69231	"Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1"
XP_050025274.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050043906.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050045595.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050045420.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050033006.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_050028879.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050035951.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050046815.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050027026.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_050051936.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050034981.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050032809.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050032722.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050026340.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050049521.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050041933.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050038335.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050030473.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_050038683.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050028334.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050025424.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050049319.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_050039331.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174154	"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin"
XP_050027527.1	7	Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22	"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_050049760.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050026116.1	3	Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426	"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050027728.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_050032473.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050046971.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050039391.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050048719.1	57	Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-532668;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780	"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome"
XP_050044032.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050052270.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050040648.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_050027217.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050049009.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_050031037.1	6	Reactome: R-HSA-5684045;Reactome: R-HSA-9603798;Reactome: R-HSA-2046105;Reactome: R-HSA-1369062;Reactome: R-HSA-2046106;Reactome: R-HSA-390247	"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Class I peroxisomal membrane protein import";"Linoleic acid (LA) metabolism";"ABC transporters in lipid homeostasis";"alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of very long chain fatty acids"
XP_050027693.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050044279.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050033454.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050045239.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050036585.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050038663.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050049718.1	12	KEGG: 00640+6.4.1.3;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.3;MetaCyc: PWY-7384;Reactome: R-HSA-3371599;Reactome: R-HSA-71032;KEGG: 00630+6.4.1.3;MetaCyc: PWY-6728;MetaCyc: PWYG-321;KEGG: 00280+6.4.1.3;Reactome: R-HSA-196780	"Propanoate metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Defective HLCS causes multiple carboxylase deficiency";"Propionyl-CoA catabolism";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"";"Valine, leucine and isoleucine degradation";"Biotin transport and metabolism"
XP_050042258.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050044090.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050024363.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050049134.1	8	MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11	"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism"
XP_050040418.1	8	KEGG: 00630+3.5.1.9;MetaCyc: PWY-7765;MetaCyc: PWY-5651;MetaCyc: PWY-6309;MetaCyc: PWY-7734;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-7733	"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Quinoxaline-2-carboxylate biosynthesis";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxyquinaldate biosynthesis"
XP_050044220.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050027659.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050042812.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050042152.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050026280.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050042265.1	7	MetaCyc: PWY-5653;MetaCyc: PWY-5316;MetaCyc: PWY-5381;MetaCyc: PWY-7342;KEGG: 00760+2.4.2.19;KEGG: 00760+6.3.4.21;Reactome: R-HSA-196807	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotine biosynthesis";"Pyridine nucleotide cycling (plants)";"Superpathway of nicotine biosynthesis";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_050051982.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050030824.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050050093.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050048547.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050049312.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050041684.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_050028129.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
XP_050050021.1	5	Reactome: R-HSA-4086400;Reactome: R-HSA-4608870;Reactome: R-HSA-373080;Reactome: R-HSA-4641262;Reactome: R-HSA-201681	"PCP/CE pathway";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT"
XP_050031782.1	10	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7344	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis"
XP_050037631.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050028884.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050037186.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_050023606.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050040117.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050044420.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050026400.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050042875.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050027921.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050025185.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050034836.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050031949.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050023094.1	2	MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050032013.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050047989.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_050042038.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050024925.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050044962.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050034716.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050026985.1	13	Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52	"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation"
XP_050045279.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050052132.1	13	Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814	"Extracellular matrix organization";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Integrin cell surface interactions";"Laminin interactions";"Signaling by PDGF";"Collagen chain trimerization";"Collagen degradation";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes"
XP_050050313.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_050028630.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050050229.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050026489.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_050030910.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050023899.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_050025708.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050030121.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050039340.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050049799.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050030176.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050040473.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050035210.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050039183.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis"
XP_050026914.1	11	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-3928665	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells"
XP_050025617.1	13	MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101	"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation"
XP_050025460.1	10	MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis"
XP_050042789.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050051508.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050039557.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050031946.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050023261.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050027405.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050047065.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_050026332.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050023870.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050023413.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050041431.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050026123.1	11	MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-7268	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_050026549.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050032528.1	18	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-379726;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;KEGG: 00970+6.1.1.1;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial tRNA aminoacylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Aminoacyl-tRNA biosynthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_050052119.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
YP_010283869.1	7	MetaCyc: PWY-4302;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-5083	"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis";"Respiratory electron transport";"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation"
XP_050048152.1	6	Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_050043944.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050050621.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-3214815	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones"
XP_050029303.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050034965.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050052410.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050030414.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050037481.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_050040982.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050049299.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050046086.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050031326.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050031742.1	6	Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690	"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events"
XP_050039666.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050041652.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050023148.1	5	Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_050034278.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050035918.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050030478.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050035988.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_050025587.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050026010.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050034740.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_050046922.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050041143.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050031830.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050049676.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050043897.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Nephrin family interactions";"Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_050042253.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_050049725.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050029407.1	8	Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208	"HSF1-dependent transactivation";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling"
XP_050023815.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_050042371.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050026555.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050047193.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050032637.1	14	MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1;KEGG: 00670+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1	"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"Folate transformations I";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"Glycine, serine and threonine metabolism";"Photorespiration ";"Glycine betaine degradation I";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"One carbon pool by folate";"Metabolism of folate and pterines";"Methane metabolism"
XP_050048853.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050027463.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050051864.1	16	Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-1251985;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001	"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"Nuclear signaling by ERBB4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade"
XP_050041600.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050038331.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050050207.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050026109.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050052568.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050031673.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050027031.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050037776.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050045003.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050045183.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050024114.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Sialic acid metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_050044700.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050046877.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050022560.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050039889.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_050034285.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050031735.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050047239.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050044813.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_050041249.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
XP_050045271.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050024273.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050026755.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
XP_050045055.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050039649.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050049872.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050040805.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050035815.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050049532.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050039616.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050026264.1	5	Reactome: R-HSA-209543;Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-9020702	"p75NTR recruits signalling complexes";"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"Interleukin-1 signaling"
XP_050052147.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_050043701.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050042251.1	7	MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050046898.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_050037442.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050027925.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050025923.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_050048290.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_050050026.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050030652.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-180746	"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein"
XP_050050143.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050045178.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050039075.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050051035.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_050033086.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050041651.1	40	MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6945;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5138;MetaCyc: PWY-6946;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00627+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-7401;MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6944;MetaCyc: PWY-5109;MetaCyc: PWY-7726;MetaCyc: PWY-5177;MetaCyc: PWY-5789;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6863;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-1361;MetaCyc: PWY-7778;KEGG: 00410+4.2.1.17;KEGG: 00592+4.2.1.17	"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"Limonene and pinene degradation";"Geraniol degradation";"Fatty acid salvage";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Lysine degradation";"Fatty acid elongation";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Carbon fixation pathways in prokaryotes";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Aminobenzoate degradation";"Benzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Pyruvate fermentation to butanol I";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Caprolactam degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Androstenedione degradation";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Tryptophan metabolism";"Butanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"2-methylpropene degradation";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism"
XP_050032803.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050034761.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050033089.1	5	Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16	"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation"
XP_050035033.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050052134.1	10	Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-111457	"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria"
XP_050030783.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050036811.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_050039958.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050028257.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_050045766.1	11	MetaCyc: PWY-6383;MetaCyc: PWY-6859;KEGG: 00900+5.3.3.2;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-7102;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-7560;MetaCyc: PWY-5123	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Methylerythritol phosphate pathway II";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_050050689.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946	"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants"
XP_050038859.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050027501.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050046959.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050041261.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_050040396.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050048344.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
XP_050037648.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_050043887.1	7	MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2	"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"Oxidative phosphorylation"
XP_050035816.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050027840.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050046085.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050043617.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050023765.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_050031611.1	10	MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001	"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050035326.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_050038989.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050037041.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050052175.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050036551.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050047739.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_050037563.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050045196.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050048436.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_050035847.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050024370.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_050030685.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050048275.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050049140.1	9	MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52	"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation"
XP_050022888.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050041691.1	10	KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10	"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Butanoate metabolism"
XP_050028330.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_050049340.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_050027408.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050030711.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050027512.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050026420.1	5	Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation";"Vitamin B6 metabolism"
XP_050050373.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764	"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling"
XP_050030678.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050034251.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050038731.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_050043781.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050046143.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050047861.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050047974.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050043962.1	9	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
XP_050026322.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050030474.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_050049626.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_050043425.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_050027597.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050045546.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050030677.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050050828.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_050038550.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_050038351.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949664	"Mitochondrial protein import";"Processing of SMDT1"
XP_050039240.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-191859	"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly"
XP_050035531.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050048485.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050035287.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050052561.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050044806.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050046045.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050051130.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050051929.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
XP_050028579.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_050044765.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_050047183.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_050024146.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295	"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"MHC class II antigen presentation"
XP_050044835.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050034242.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_050039850.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050052029.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050039362.1	9	MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883	"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II"
XP_050044603.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050028966.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050029490.1	18	MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Purine metabolism"
XP_050044584.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050042629.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"MASTL Facilitates Mitotic Progression";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050047402.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050045333.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050049401.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050032805.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_050036235.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050028738.1	6	MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067	"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_050044790.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050025262.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050027387.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050035932.1	34	Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531	"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus"
XP_050028556.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050043007.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050046804.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050031199.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050025647.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050047547.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050027932.1	4	KEGG: 00633+2.3.1.5;KEGG: 00983+2.3.1.5;KEGG: 00232+2.3.1.5;Reactome: R-HSA-156582	"Nitrotoluene degradation";"Drug metabolism - other enzymes";"Caffeine metabolism";"Acetylation"
XP_050043901.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68616	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication"
XP_050046173.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050023272.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050047840.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050042092.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050051406.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050045192.1	19	KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-1622;MetaCyc: PWY-561;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;Reactome: R-HSA-71403	"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citric acid cycle (TCA cycle)"
XP_050043469.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300	"DNA methylation";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA"
XP_050024348.1	4	Reactome: R-HSA-3232142;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664	"SUMOylation of ubiquitinylation proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation"
XP_050036232.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050036768.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050026018.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050030768.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050052180.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050047290.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050024651.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_050032909.1	5	KEGG: 00983+2.7.1.21;Reactome: R-HSA-73614;Reactome: R-HSA-69205;KEGG: 00240+2.7.1.21;MetaCyc: PWY-7199	"Drug metabolism - other enzymes";"Pyrimidine salvage";"G1/S-Specific Transcription";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage"
XP_050040275.1	5	KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_050033834.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050052573.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050052268.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050052559.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050032122.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-164378	"DARPP-32 events";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA activation in glucagon signalling"
XP_050030956.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050036382.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050036413.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050039191.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598	"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis"
XP_050035204.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050052131.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050048419.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045147.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_050052058.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050049531.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183	"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand"
XP_050027133.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050050702.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775	"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis"
XP_050042255.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050044464.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050051746.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050038825.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050052636.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050039290.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_050035124.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050048329.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050039971.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050051647.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050036364.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_050037097.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex"
XP_050029929.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050039246.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050047799.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050037401.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-69601	"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_050034734.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050027712.1	4	MetaCyc: PWY-5028;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5030;Reactome: R-HSA-70921	"L-histidine degradation II";"Histidine metabolism";"L-histidine degradation III";"Histidine catabolism"
XP_050038862.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690	"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Early Events"
XP_050048952.1	5	MetaCyc: PWY-4983;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"Arginine and proline metabolism"
XP_050046875.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050024005.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050036999.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050050899.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050027690.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050029335.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050037700.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_050032996.1	5	Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168	"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_050031823.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_050036605.1	3	Reactome: R-HSA-1234158;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664	"Regulation of gene expression by Hypoxia-inducible Factor";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation"
XP_050026281.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050049410.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_050023360.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050025862.1	6	KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050050544.1	12	MetaCyc: PWY-601;MetaCyc: PWY-6936;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-6842	"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Glutathione-mediated detoxification II"
XP_050049909.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050049527.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_050025879.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921	"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"Ion homeostasis";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation"
XP_050031737.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050045557.1	7	Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER"
XP_050052094.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204	"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_050039484.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167158	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex"
XP_050038561.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_050039612.1	6	KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism"
XP_050031828.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050034910.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050039132.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050038127.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_050048624.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050036026.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050038628.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176407	"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050024912.1	4	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_050028857.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050028872.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050029305.1	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050027573.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050047472.1	5	KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695	"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation"
XP_050045760.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050025094.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050040583.1	8	MetaCyc: PWY-7733;MetaCyc: PWY-7717;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-5651;MetaCyc: PWY-6309;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7765	"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
XP_050026287.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050030558.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050024301.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050029239.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050051200.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243	"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Neutrophil degranulation";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050037561.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050029368.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050029167.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_050047138.1	7	Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214	"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins"
XP_050026567.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383	"Ansatrienin biosynthesis";"Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050042923.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050045765.1	11	Reactome: R-HSA-191273;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-7560;MetaCyc: PWY-7102;MetaCyc: PWY-922;MetaCyc: PWY-6174	"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methylerythritol phosphate pathway II";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)"
XP_050045189.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-77595;Reactome: R-HSA-674695;Reactome: R-HSA-77588;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-9010553;Reactome: R-HSA-113418;Reactome: R-HSA-72203;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-975956;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-167158;Reactome: R-HSA-159227;Reactome: R-HSA-191859	"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Pre-transcription Events";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Regulation of expression of SLITs and ROBOs";"Formation of the Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly"
XP_050027738.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050025343.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050035844.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050050875.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050031902.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050052683.1	10	MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9	"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes"
XP_050044093.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_050048462.1	17	Reactome: R-HSA-200425;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
XP_050052512.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408	"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation"
XP_050031575.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_050050267.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
XP_050034521.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050036757.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050039540.1	14	KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-7767;MetaCyc: PWY-5103;MetaCyc: PWY-5057;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5101;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5078;Reactome: R-HSA-70895;KEGG: 00290+2.6.1.42	"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis III";"L-valine degradation II";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis II";"Pantothenate and CoA biosynthesis";"L-leucine degradation III";"L-isoleucine degradation II";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine biosynthesis"
XP_050025230.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050049284.1	7	MetaCyc: PWY-6351;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis"
XP_050028088.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050052554.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050042593.1	3	Reactome: R-HSA-5678520;Reactome: R-HSA-159418;Reactome: R-HSA-193368	"Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2";"Recycling of bile acids and salts";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"
XP_050035420.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050041565.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050029860.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459	"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050051438.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_050050492.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050031896.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system"
XP_050028542.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050041744.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050025550.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_050034745.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050026388.1	7	MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500	"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle"
XP_050044192.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_050030568.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050031785.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_050047891.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050037012.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050023434.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
XP_050044005.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050023764.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_050049831.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050044722.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050036676.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)"
XP_050044767.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050041757.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050034759.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_050034860.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050040054.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_050045601.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050033094.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_050041348.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_050034596.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050037624.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050040958.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_050044008.1	33	Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-168333	"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Mitotic Prometaphase";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050046574.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050027084.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins"
XP_050023492.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_050029360.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_050045301.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050023115.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045465.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050030718.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050026481.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050038754.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050034209.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862	"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050049917.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050037522.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050033894.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis"
XP_050044197.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis"
XP_050036144.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_050050545.1	14	Reactome: R-HSA-8964208;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-2821;Reactome: R-HSA-8964539;MetaCyc: PWY-6936;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;Reactome: R-HSA-71240	"Phenylalanine metabolism";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glutamate and glutamine metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Tryptophan catabolism"
XP_050041583.1	4	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_050034239.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_050040153.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050034252.1	3	KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_050037148.1	12	MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism"
XP_050050799.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050033511.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050033998.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050044106.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050033610.1	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
XP_050029163.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050031962.1	9	KEGG: 00401+2.6.1.5;KEGG: 00960+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00350+2.6.1.5	"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism"
XP_050046514.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050044411.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_050050561.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050051771.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_050042536.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050030511.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050030095.1	5	KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation"
XP_050044345.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050044541.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050037626.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_050025980.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050048094.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050038747.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_050033791.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050044358.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050026202.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050036219.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050040484.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050039552.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050052556.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050027283.1	10	KEGG: 00240+2.1.1.45;MetaCyc: PWY-7187;Reactome: R-HSA-499943;Reactome: R-HSA-69205;MetaCyc: PWY-7199;KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"One carbon pool by folate";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_050049596.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050049879.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050022906.1	9	MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-7115	"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_050026723.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050052750.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050040704.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050039156.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050048829.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050032857.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050042950.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050040160.1	6	MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183	"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050051747.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050027292.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050029428.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050042366.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_050045740.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-170670	"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway"
XP_050041934.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050030571.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050033513.1	5	KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3	"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_050030819.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050037574.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation"
XP_050044831.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_050045112.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050046475.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050041422.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050039886.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050031956.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-909733	"Interferon gamma signaling";"Interferon alpha/beta signaling"
XP_050049555.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state"
XP_050025911.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050040693.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_050025843.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050047787.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050038864.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638	"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins"
XP_050040626.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050052024.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050046988.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050029351.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050031895.1	5	MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41	"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
XP_050025184.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050048188.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_050029442.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050034477.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050047793.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050038765.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_050045258.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_050043468.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300	"DNA methylation";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA"
XP_050050372.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050028745.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis"
XP_050035433.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_050036609.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050032595.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050036850.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade"
XP_050032868.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_050023786.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050042037.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050047848.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_050045759.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_050049877.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050023774.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050042095.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050032523.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050032065.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050044482.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050045664.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050032602.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050046076.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050044446.1	8	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"mTOR signaling pathway"
XP_050047332.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050025353.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050035114.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-428890;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-8854518;Reactome: R-HSA-141444;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-2565942	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Role of ABL in ROBO-SLIT signaling";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Regulation of PLK1 Activity at G2/M Transition"
XP_050027719.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050033589.1	11	MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-210455;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2	"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Arginine biosynthesis"
XP_050052095.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_050034450.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050043059.1	1	Reactome: R-HSA-71240	"Tryptophan catabolism"
XP_050040740.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_050042205.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism"
XP_050051439.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_050047867.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_050039545.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050043603.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050024153.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_050025566.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050042817.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050043492.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_050048789.1	1	KEGG: 00760+1.4.1.21	"Nicotinate and nicotinamide metabolism"
XP_050024487.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050050833.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050028704.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050034884.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050030051.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_050050685.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775	"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF activation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis"
XP_050027721.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050047479.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050049762.1	24	Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295	"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"MHC class II antigen presentation"
XP_050050302.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050027439.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050037625.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050035527.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050041312.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050052753.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050052036.1	8	MetaCyc: PWY-6664;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-4661;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4	"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism"
XP_050043827.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050033573.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050044575.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050052701.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation"
XP_050049220.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050032585.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050025555.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050047478.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050035540.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050032706.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050049820.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050026022.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050048499.1	10	Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_050029775.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_050049308.1	2	Reactome: R-HSA-375281;Reactome: R-HSA-416476	"Hormone ligand-binding receptors";"G alpha (q) signalling events"
XP_050045385.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050041701.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050043143.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050030762.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050039148.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050044129.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050028746.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050032804.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050027657.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-1169091	"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"Activation of NF-kappaB in B cells"
XP_050040734.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050043130.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050037398.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8941858	"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity"
XP_050049860.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_050027436.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050048383.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361	"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Neurexins and neuroligins"
XP_050032850.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050052700.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_050040148.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050036655.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050037727.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050035194.1	12	MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism"
XP_050024786.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050031607.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_050022746.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050026316.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050050709.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050049822.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050052716.1	14	KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-6842;MetaCyc: PWY-601;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;Reactome: R-HSA-8964208;Reactome: R-HSA-8964539;MetaCyc: PWY-7901;MetaCyc: PWY-2821	"Cysteine and methionine metabolism";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Phenylalanine metabolism";"Glutamate and glutamine metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine"
XP_050041976.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050051286.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_050031873.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050026413.1	18	KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00350+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7383;KEGG: 00270+2.6.1.1	"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Isoquinoline alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Tyrosine metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Sulfolactate degradation III";"Arginine biosynthesis";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism"
XP_050047165.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050048793.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_050027595.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050034360.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_050048007.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050044270.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050032875.1	3	KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis"
XP_050044982.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-9010553	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs"
XP_050046156.1	37	Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-204005;Reactome: R-HSA-68877;Reactome: R-HSA-983170;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9639288;Reactome: R-HSA-180910;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-165054	"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"COPII-mediated vesicle transport";"Mitotic Prometaphase";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Amino acids regulate mTORC1";"Vpr-mediated nuclear import of PICs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA"
XP_050030714.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050043538.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050023516.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050047716.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_050042873.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_050041728.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050027203.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050038368.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050029164.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050025351.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_050030148.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_050042707.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049305.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050046029.1	9	Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_050027033.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050026008.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050038119.1	5	MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32	"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_050036875.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_050024013.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050039701.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050032575.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050031201.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050047548.1	6	Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-110362	"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair"
XP_050033241.1	5	Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-376172	"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"p38MAPK events";"NOD1/2 Signaling Pathway";"DSCAM interactions"
XP_050027590.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050033902.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050050694.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation"
XP_050047586.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050043350.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050048798.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050033723.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"Neddylation";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050028497.1	3	MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_050034537.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_050047181.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-69481	"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Activation of NF-kappaB in B cells";"G2/M Checkpoints"
XP_050044963.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050026170.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050037297.1	3	KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_050023381.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050042111.1	24	Reactome: R-HSA-5610780;Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-4420097;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-111931;Reactome: R-HSA-9010642;Reactome: R-HSA-5610783;Reactome: R-HSA-163560;Reactome: R-HSA-164378;Reactome: R-HSA-392517;Reactome: R-HSA-163615;Reactome: R-HSA-5610785;Reactome: R-HSA-432040;Reactome: R-HSA-5621575;KEGG: 04150+2.7.11.11;Reactome: R-HSA-8853659;Reactome: R-HSA-8963896;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-442720	"Degradation of GLI1 by the proteasome";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"VEGFA-VEGFR2 Pathway";"Hedgehog 'off' state";"DARPP-32 events";"PKA-mediated phosphorylation of CREB";"ROBO receptors bind AKAP5";"Degradation of GLI2 by the proteasome";"Triglyceride catabolism";"PKA activation in glucagon signalling";"Rap1 signalling";"PKA activation";"GLI3 is processed to GLI3R by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins";"CD209 (DC-SIGN) signaling";"mTOR signaling pathway";"RET signaling";"HDL assembly";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_050029409.1	8	Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_050036002.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050027825.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-211981;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211976	"Phase I - Functionalization of compounds";"Xenobiotics";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Endogenous sterols"
XP_050036710.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050031947.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050033247.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_050039796.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050041495.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050051869.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-419771	"G alpha (i) signalling events";"Opsins"
XP_050030582.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_050023898.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695	"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Interleukin-7 signaling"
XP_050044688.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050052235.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050038428.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050032145.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_050043302.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050049199.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_050038132.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_050045658.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050026417.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050046019.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050049094.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050049277.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
XP_050048776.1	22	Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025	"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"RAF activation";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation"
XP_050023300.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050035101.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050036004.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050022491.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050049350.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050022843.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050049233.1	6	Reactome: R-HSA-6811440;Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_050043439.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD"
XP_050045121.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050036881.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050043113.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050047847.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_050048823.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN"
XP_050022608.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050040549.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050039363.1	9	KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis"
XP_050048420.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050051087.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-450408	"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_050030765.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050034738.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_050035718.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050035987.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050035687.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050032853.1	83	Reactome: R-HSA-8853334;Reactome: R-HSA-354194;Reactome: R-HSA-1963640;Reactome: R-HSA-2029482;Reactome: R-HSA-9026519;Reactome: R-HSA-2424491;Reactome: R-HSA-180292;Reactome: R-HSA-8856828;Reactome: R-HSA-375165;Reactome: R-HSA-6807004;Reactome: R-HSA-1250196;Reactome: R-HSA-5654704;Reactome: R-HSA-167044;Reactome: R-HSA-912631;Reactome: R-HSA-74751;Reactome: R-HSA-5654710;Reactome: R-HSA-2871796;Reactome: R-HSA-186763;Reactome: R-HSA-74749;Reactome: R-HSA-5654699;Reactome: R-HSA-5655291;Reactome: R-HSA-9634285;Reactome: R-HSA-5637810;Reactome: R-HSA-5654693;Reactome: R-HSA-9027284;Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-5654712;Reactome: R-HSA-1963642;Reactome: R-HSA-983695;Reactome: R-HSA-8875555;Reactome: R-HSA-5655302;Reactome: R-HSA-8875656;Reactome: R-HSA-5654700;Reactome: R-HSA-8853659;Reactome: R-HSA-391160;Reactome: R-HSA-5673001;Reactome: R-HSA-388841;Reactome: R-HSA-9664565;Reactome: R-HSA-5654727;Reactome: R-HSA-179812;Reactome: R-HSA-112412;Reactome: R-HSA-8865999;Reactome: R-HSA-1236382;Reactome: R-HSA-5654695;Reactome: R-HSA-5654732;Reactome: R-HSA-180336;Reactome: R-HSA-210993;Reactome: R-HSA-8851805;Reactome: R-HSA-5655253;Reactome: R-HSA-1250347;Reactome: R-HSA-5654706;Reactome: R-HSA-9028335;Reactome: R-HSA-2179392;Reactome: R-HSA-2871809;Reactome: R-HSA-5654689;Reactome: R-HSA-1257604;Reactome: R-HSA-9034864;Reactome: R-HSA-8875360;Reactome: R-HSA-9645135;Reactome: R-HSA-9028731;Reactome: R-HSA-5654726;Reactome: R-HSA-6811558;Reactome: R-HSA-2428933;Reactome: R-HSA-5654719;Reactome: R-HSA-8851907;Reactome: R-HSA-1433557;Reactome: R-HSA-8983432;Reactome: R-HSA-1433559;Reactome: R-HSA-109704;Reactome: R-HSA-1839117;Reactome: R-HSA-2219530;Reactome: R-HSA-5663213;Reactome: R-HSA-8853338;Reactome: R-HSA-5654688;Reactome: R-HSA-182971;Reactome: R-HSA-9607240;Reactome: R-HSA-8856825;Reactome: R-HSA-389359;Reactome: R-HSA-5654720;Reactome: R-HSA-2730905;Reactome: R-HSA-912526;Reactome: R-HSA-512988	"Signaling by FGFR3 fusions in cancer";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"GRB2 events in ERBB2 signaling";"Regulation of actin dynamics for phagocytic cup formation";"Activated NTRK2 signals through RAS";"DAP12 signaling";"GAB1 signalosome";"Clathrin-mediated endocytosis";"NCAM signaling for neurite out-growth";"Negative regulation of MET activity";"SHC1 events in ERBB2 signaling";"SHC-mediated cascade:FGFR3";"Signalling to RAS";"Regulation of signaling by CBL";"Insulin receptor signalling cascade";"PI-3K cascade:FGFR3";"FCERI mediated MAPK activation";"Downstream signal transduction";"Signal attenuation";"SHC-mediated cascade:FGFR2";"Signaling by FGFR4 in disease";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by EGFRvIII";"FRS-mediated FGFR1 signaling";"Erythropoietin activates RAS";"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"FRS-mediated FGFR4 signaling";"PI3K events in ERBB2 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"MET activates RAP1 and RAC1";"Signaling by FGFR1 in disease";"MET receptor recycling";"FRS-mediated FGFR2 signaling";"RET signaling";"Signal regulatory protein family interactions";"RAF/MAP kinase cascade";"Costimulation by the CD28 family";"Signaling by ERBB2 KD Mutants";"Negative regulation of FGFR2 signaling";"GRB2 events in EGFR signaling";"SOS-mediated signalling";"MET activates PTPN11";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI-3K cascade:FGFR2";"Negative regulation of FGFR3 signaling";"SHC1 events in EGFR signaling";"Tie2 Signaling";"MET activates RAS signaling";"Signaling by FGFR2 in disease";"SHC1 events in ERBB4 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through PI3K";"EGFR Transactivation by Gastrin";"FCERI mediated Ca+2 mobilization";"PI-3K cascade:FGFR1";"PIP3 activates AKT signaling";"Activated NTRK3 signals through RAS";"InlB-mediated entry of Listeria monocytogenes into host cell";"STAT5 Activation";"Activated NTRK2 signals through FRS2 and FRS3";"Negative regulation of FGFR1 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC-related events triggered by IGF1R";"SHC-mediated cascade:FGFR4";"MET activates PI3K/AKT signaling";"Signaling by SCF-KIT";"Interleukin-15 signaling";"Regulation of KIT signaling";"PI3K Cascade";"Signaling by cytosolic FGFR1 fusion mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"RHO GTPases Activate WASPs and WAVEs";"Signaling by FGFR3 point mutants in cancer";"SHC-mediated cascade:FGFR1";"EGFR downregulation";"FLT3 Signaling";"Cargo recognition for clathrin-mediated endocytosis";"CD28 dependent Vav1 pathway";"PI-3K cascade:FGFR4";"Role of LAT2/NTAL/LAB on calcium mobilization";"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_050052424.1	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
XP_050045930.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_050031626.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670	"MHC class II antigen presentation";"Sialic acid metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis"
XP_050045332.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050049221.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050046897.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050045542.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050047287.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050034595.1	16	Reactome: R-HSA-381426;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-1474228;Reactome: R-HSA-2660826;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-8957275;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-1442490	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Amyloid fiber formation";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Post-translational protein phosphorylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Collagen degradation"
XP_050033317.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050048062.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050048564.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_050025341.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_050023810.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050050654.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050036221.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050032981.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_050048137.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050035559.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050048400.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050032111.1	5	MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_050042722.1	3	Reactome: R-HSA-382556;Reactome: R-HSA-1989781;Reactome: R-HSA-5678771	"ABC-family proteins mediated transport";"PPARA activates gene expression";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1"
XP_050044357.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050029787.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050025267.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050033233.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050044793.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050051578.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_050036085.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050051710.1	3	Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_050032514.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_050041414.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050040326.1	5	MetaCyc: PWY-6012-1;Reactome: R-HSA-199220;MetaCyc: PWY-6289;MetaCyc: PWY-6012;KEGG: 00770+2.7.8.7	"Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism";"Petrobactin biosynthesis";"Acyl carrier protein metabolism";"Pantothenate and CoA biosynthesis"
XP_050026798.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050046064.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_050030634.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-1234176;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-674695	"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events"
XP_050029423.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050052158.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation"
XP_050030507.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA"
XP_050038226.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050023195.1	7	MetaCyc: PWY-7176;MetaCyc: PWY-7219;KEGG: 00983+2.7.4.14;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14	"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine metabolism"
XP_050029059.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842	"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_050038349.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050044776.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050051294.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050049713.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050023320.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050050805.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050038429.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050034567.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050031832.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_050041874.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050047675.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050050765.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050025335.1	7	KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;MetaCyc: PWY-7625	"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_050048770.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050035463.1	4	MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22	"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism"
XP_050049096.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050030747.1	12	KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803	"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_050027415.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51	"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism"
XP_050049586.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport"
XP_050049910.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050027029.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_050049295.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050041849.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050040157.1	6	KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane"
XP_050023419.1	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050051579.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013	"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_050049627.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050024734.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049051.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_050048517.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_050050321.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050026623.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050030321.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050049345.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050042738.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050041739.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050048005.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism"
XP_050048804.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_050033319.1	8	Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-8941284	"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Activation of SMO";"RUNX2 regulates chondrocyte maturation"
XP_050033371.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050042945.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050046001.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050052816.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_050051478.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050034728.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_050048466.1	17	KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2	"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism"
XP_050024014.1	10	MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_050025942.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy"
XP_050026800.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050023719.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050039611.1	6	MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism"
XP_050026118.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050037622.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050051765.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis"
XP_050023623.1	13	MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-5122	"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Geranyl diphosphate biosynthesis"
XP_050038592.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_050040644.1	10	MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Methane metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_050050201.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050039428.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050037035.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_050044122.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050037285.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050047846.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_050045592.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050039365.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_050024580.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050028318.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation"
XP_050030467.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050031592.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_050038846.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_050028953.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027139.1	5	Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720	"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis"
XP_050034320.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050025425.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050041844.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050044786.1	11	Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558	"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_050043035.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050040278.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050052194.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050044395.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_050049880.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050023398.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842	"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II"
XP_050042924.1	5	KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403	"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling"
XP_050033843.1	14	MetaCyc: PWY-5690;MetaCyc: PWY-7279;MetaCyc: PWY-3781;Reactome: R-HSA-611105;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-561	"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_050042902.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050025590.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050047705.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050038325.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-9609523;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050032711.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_050043794.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050040901.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_050036851.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_050039093.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050046833.1	6	Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653	"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_050029085.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050029406.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"HSF1-dependent transactivation";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_050036415.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050033200.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892	"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_050032546.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050039856.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050035219.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050033627.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050024095.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_050032632.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_050035999.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050030481.1	13	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Other glycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Keratan sulfate degradation"
XP_050048632.1	9	MetaCyc: PWY-6147;MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_050026261.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050023553.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050036162.1	9	Reactome: R-HSA-70263;Reactome: R-HSA-3371599;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146	"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism"
XP_050032372.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_050033432.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_050042096.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050037869.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_050034281.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050035116.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-428890;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-68877;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-380284	"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Role of ABL in ROBO-SLIT signaling";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050052809.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_050040707.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_050048958.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050037456.1	14	Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;MetaCyc: PWY-7782;MetaCyc: PWY-8051	"Synthesis of PE";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PC";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I"
XP_050031197.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050023695.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_050045176.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050026390.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050039504.1	7	KEGG: 00620+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_050030515.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050050868.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050026323.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050025495.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050034064.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050025197.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050047054.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050043898.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-186763	"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Activation of RAC1";"Downstream signal transduction"
XP_050050757.1	9	Reactome: R-HSA-5628897;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"MAP2K and MAPK activation";"Neutrophil degranulation";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050046951.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050051414.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050029753.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050033844.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050038567.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050043907.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050030716.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050049584.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_050047905.1	9	Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18	"Glutathione conjugation";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450"
XP_050028060.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050051137.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050045958.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_050030826.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050048418.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_050051444.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050040647.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050035730.1	3	KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383	"Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism"
XP_050025801.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050029645.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_050022476.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050041923.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_050030628.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_050026317.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050043599.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050027483.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050027251.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050047999.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050049100.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050050645.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610783	"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome"
XP_050043810.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050046067.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_050026313.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-9630221	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing"
XP_050052502.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050052209.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050030249.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050027156.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050034333.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050036728.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity"
XP_050051442.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050034733.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_050038320.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050045126.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050040292.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050037317.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050024903.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050027670.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_050043884.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050041857.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050027671.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050036456.1	4	KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;KEGG: 00010+3.1.3.9;Reactome: R-HSA-70263	"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_050026054.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050041331.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050024486.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050034829.1	9	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050040643.1	10	MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis"
XP_050044614.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050040459.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050034159.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_050047366.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050029298.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050042139.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050045666.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050049497.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_050025937.1	12	MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5857	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_050051915.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884	"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX"
XP_050026547.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050028275.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050051365.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050035536.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050037628.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050023868.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050048268.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_050039323.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050047034.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050051980.1	5	Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695	"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation"
XP_050044623.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050041375.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_050023615.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050029426.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050026551.1	12	Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-982772;Reactome: R-HSA-75893;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Growth hormone receptor signaling";"TNF signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation"
XP_050049242.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050051981.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation"
XP_050042222.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050023146.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050033342.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050023797.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050041760.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050050606.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050044452.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_050031488.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050035016.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050039485.1	14	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167200	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050034458.1	3	KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383	"Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism"
XP_050045962.1	4	MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050023334.1	19	Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-381426	"Chylomicron remodeling";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Chylomicron assembly";"Scavenging by Class H Receptors";"VLDL clearance";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050038184.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168	"Neutrophil degranulation";"Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045265.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050030600.1	13	MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes"
XP_050029737.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050036853.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_050031383.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050047313.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_050049815.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_050042816.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050043117.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050042936.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050049870.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050024072.1	4	MetaCyc: PWY-6972;Reactome: R-HSA-382556;Reactome: R-HSA-5679001;Reactome: R-HSA-189483	"Oleandomycin activation/inactivation";"ABC-family proteins mediated transport";"Defective ABCC2 causes Dubin-Johnson syndrome";"Heme degradation"
XP_050044728.1	7	MetaCyc: PWY-5659;MetaCyc: PWY-7456;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;KEGG: 00051+5.4.2.8	"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_050044451.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050025277.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050051055.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050044454.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_050045998.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050044435.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050031230.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050051798.1	12	KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6932;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4	"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Selenate reduction";"Transport and synthesis of PAPS";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Selenocompound metabolism"
XP_050047002.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_050047731.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_050052839.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050023745.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050033725.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050032936.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050050719.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_050040645.1	10	MetaCyc: PWY-1861;MetaCyc: PWY-7385;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Methane metabolism"
XP_050037108.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050034933.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118	"Triglyceride catabolism";"Glycerol degradation I";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle"
XP_050023883.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050041283.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_050031824.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050029420.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050043038.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_050043474.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050051989.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050047516.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050022718.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_050037067.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050052684.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050039302.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis"
XP_050030758.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050024733.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050040327.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050032645.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050040075.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207	"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_050050106.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050031078.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_050049864.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050034959.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050028248.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050034480.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050045602.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050031249.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050022875.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050034532.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050041634.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050046136.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050044475.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603	"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases"
XP_050034615.1	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2	"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Photosynthesis"
XP_050030154.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050028159.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050029373.1	2	KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6	"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism"
XP_050040986.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050025459.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-4041	"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle"
XP_050030425.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes"
XP_050028605.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050051299.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_050046172.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050051690.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_050041423.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050025549.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_050044622.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050036270.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050047374.1	7	Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-2559580;Reactome: R-HSA-69541;Reactome: R-HSA-2559585	"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Oxidative Stress Induced Senescence";"Stabilization of p53";"Oncogene Induced Senescence"
XP_050044404.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_050052656.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050029319.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050051050.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050029052.1	10	MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001	"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050044704.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050050141.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050050758.1	21	Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-5602636;Reactome: R-HSA-1169091;Reactome: R-HSA-1810476;Reactome: R-HSA-1236974;Reactome: R-HSA-168927;Reactome: R-HSA-937041;Reactome: R-HSA-5357905;Reactome: R-HSA-933542;Reactome: R-HSA-202424;Reactome: R-HSA-933543;Reactome: R-HSA-5603027;Reactome: R-HSA-5684264;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-5603029;Reactome: R-HSA-9020702;Reactome: R-HSA-168638	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IKBKB deficiency causes SCID";"Activation of NF-kappaB in B cells";"RIP-mediated NFkB activation via ZBP1";"ER-Phagosome pathway";"TICAM1, RIP1-mediated IKK complex recruitment";"IKK complex recruitment mediated by RIP1";"Regulation of TNFR1 signaling";"TRAF6 mediated NF-kB activation";"Downstream TCR signaling";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"IkBA variant leads to EDA-ID";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway"
XP_050028105.1	3	Reactome: R-HSA-156581;Reactome: R-HSA-5578995;KEGG: 00983+2.1.1.67	"Methylation";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Drug metabolism - other enzymes"
XP_050040710.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050049662.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050049549.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050025914.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050033730.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050033316.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050035319.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050033073.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050046921.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050042683.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050042906.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050035922.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050023601.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050028237.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619	"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN"
XP_050049336.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050045224.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555	"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events"
XP_050044697.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_050022553.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_050045296.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050051386.1	7	MetaCyc: PWY-7184;MetaCyc: PWY-7185;MetaCyc: PWY-7198;KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.15	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism"
XP_050041921.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050050862.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_050031948.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050036810.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_050052420.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295	"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"MHC class II antigen presentation"
XP_050035822.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050040888.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_050037416.1	11	Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050025508.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050047167.1	3	MetaCyc: PWY-40;Reactome: R-HSA-351143;KEGG: 00330+3.5.3.11	"Putrescine biosynthesis I";"Agmatine biosynthesis";"Arginine and proline metabolism"
XP_050027250.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050051695.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050047981.1	7	Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-6134	"Phenylketonuria";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"Folate biosynthesis";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV"
XP_050027181.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050029772.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050049316.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050039349.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050041543.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_050047030.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050038336.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050045284.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050028790.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045748.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_050023843.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050045145.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050047587.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050042044.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050038897.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050023282.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050028158.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050023585.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050047289.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050050795.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_050044347.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050052129.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050039993.1	6	KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21	"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_050047838.1	8	KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;Reactome: R-HSA-6787639;MetaCyc: PWY-66;MetaCyc: PWY-5739;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-5738	"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-colitose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis"
XP_050036240.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050033673.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050040715.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050028703.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050032978.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_050026399.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050042563.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_050037457.1	14	MetaCyc: PWY-8052;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213	"2-arachidonoylglycerol biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Synthesis of PE"
XP_050049230.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050048385.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6	"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism"
XP_050052578.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050031819.1	4	MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_050042179.1	6	MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism"
XP_050032928.1	8	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_050038322.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050037414.1	16	Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-9018519;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-201722;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-2559586	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Estrogen-dependent gene expression";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Formation of the beta-catenin:TCF transactivating complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence"
XP_050023263.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050044970.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050039403.1	5	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050029825.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_050037902.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050049228.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050048357.1	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
XP_050024880.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050039430.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050050102.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050042990.1	10	Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Thermogenesis";"HATs acetylate histones";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050046968.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050049569.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050022895.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-241;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5789	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_050027638.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_050029080.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_050046185.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050045285.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050032478.1	17	Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-3270619;Reactome: R-HSA-5693565	"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"IRF3-mediated induction of type I IFN";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050023979.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050027120.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_050029827.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426486	"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis"
XP_050051155.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050047286.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050025978.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050047964.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050026488.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050046911.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050037147.1	12	MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_050047192.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050050820.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050038900.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050027801.1	11	Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050025612.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050029843.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050050589.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537	"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_050034867.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050022940.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050051482.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050025186.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050027547.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050044841.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050036644.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050044843.1	6	Reactome: R-HSA-381340;Reactome: R-HSA-3238698;Reactome: R-HSA-201681;Reactome: R-HSA-4641262;Reactome: R-HSA-4086400;Reactome: R-HSA-373080	"Transcriptional regulation of white adipocyte differentiation";"WNT ligand biogenesis and trafficking";"TCF dependent signaling in response to WNT";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PCP/CE pathway";"Class B/2 (Secretin family receptors)"
XP_050045915.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050024450.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-877300	"Interferon alpha/beta signaling";"Interferon gamma signaling"
XP_050026673.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_050032816.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050030959.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050038315.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050040401.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050044620.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050030754.1	6	MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050040996.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050049921.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050047771.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_050041236.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050036465.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_050047809.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Neddylation";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway"
XP_050031196.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050025293.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050039359.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69183	"Activation of the pre-replicative complex";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand"
XP_050052572.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050041002.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050024699.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050030331.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050026014.1	4	MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I"
XP_050036237.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_050037096.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_050023494.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050029388.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050033331.1	57	Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780	"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome"
XP_050049239.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050024466.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050051074.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_050045525.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050042042.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050028752.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050029836.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050050082.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050045825.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_050049561.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166	"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade"
XP_050029375.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_050025114.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_050025635.1	15	Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152	"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_050035272.1	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050049927.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050040154.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050026823.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050025887.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050023783.1	7	KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-7836;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_050052580.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050035446.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_050033356.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050040040.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050049294.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_050047361.1	29	Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400	"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER"
XP_050035957.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050031043.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050038531.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050038435.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351	"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_050051535.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050042195.1	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
XP_050026423.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050049399.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050051446.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050038866.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168276	"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways"
XP_050045175.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050038837.1	6	KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7395	"Galactose metabolism";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_050023219.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050042250.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_050022596.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050052685.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050045181.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050028430.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050044168.1	4	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I"
XP_050049984.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050046455.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050035199.1	12	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I"
XP_050026047.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593	"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity"
XP_050026303.1	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050033577.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050047984.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050024862.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050044437.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050047050.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050024936.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228	"Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix"
XP_050045182.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050025261.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050031398.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-909733	"Interferon gamma signaling";"Interferon alpha/beta signaling"
XP_050044905.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050035944.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050049072.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_050023844.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050051364.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050044531.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050035435.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_050052148.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_050042304.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-5674400	"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_050042954.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_050030955.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050035195.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409	"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_050025671.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050045709.1	3	Reactome: R-HSA-913709;Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"O-linked glycosylation of mucins";"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050046070.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050045150.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050045372.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_050043328.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050047067.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050022492.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050034409.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_050031262.1	11	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050044937.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050027578.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway"
XP_050024081.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050051317.1	9	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-4420097	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway"
XP_050052400.1	33	KEGG: 00626+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-5076;MetaCyc: PWY-7013;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6342;MetaCyc: PWY-5486;MetaCyc: PWY-6333;MetaCyc: PWY-5480;MetaCyc: PWY-6802;MetaCyc: PWY-5082;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7111;KEGG: 00830+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-1801;MetaCyc: PWY-6313;MetaCyc: PWY-6871;MetaCyc: PWY-7798;MetaCyc: PWY-7396;Reactome: R-HSA-71384;MetaCyc: PWY-5079;KEGG: 00982+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00071+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5078;MetaCyc: PWY-7118;MetaCyc: PWY-5057	"Naphthalene degradation";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol III";"L-leucine degradation III";"(S)-propane-1,2-diol degradation";"Methane metabolism";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol II";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol I";"Salidroside biosynthesis";"L-methionine degradation III";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to isobutanol (engineered)";"Retinol metabolism";"alpha-Linolenic acid metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Serotonin degradation";"3-methylbutanol biosynthesis (engineered)";"Protein S-nitrosylation and denitrosylation";"Butanol and isobutanol biosynthesis (engineered)";"Ethanol oxidation";"L-phenylalanine degradation III";"Drug metabolism - cytochrome P450";"L-tryptophan degradation V (side chain pathway)";"Fatty acid degradation";"Glycine, serine and threonine metabolism";"Metabolism of xenobiotics by cytochrome P450";"Phenylethanol biosynthesis";"Tyrosine metabolism";"L-isoleucine degradation II";"Chitin degradation to ethanol";"L-valine degradation II"
XP_050049522.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050038827.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050031855.1	9	KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590	"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation"
XP_050051355.1	26	Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148	"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050039202.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050029369.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050024879.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_050049114.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1	"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism"
XP_050024939.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050051949.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050050683.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"RAF activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions"
XP_050026124.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050040998.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050030444.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050037421.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050026120.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050036568.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_050044387.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050025223.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_050033980.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050042721.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-5678771;Reactome: R-HSA-382556	"PPARA activates gene expression";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"ABC-family proteins mediated transport"
XP_050038705.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_050039107.1	5	KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_050037315.1	4	Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-975144	"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_050042242.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423	"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Chylomicron assembly";"VLDL clearance";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"VLDL assembly"
XP_050034757.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050038333.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_050037316.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex"
XP_050040716.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_050035325.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050037164.1	18	MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7115;MetaCyc: PWY-561;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37	"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms"
XP_050051991.1	8	MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_050050278.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050047280.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050051141.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_050050684.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892	"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation"